OpenMed/multicare-articles huggingface dataset:
A Rare Presentation of Inflammatory Myofibroblastic Tumor in the Nasolabial Fold
Authors: Hind K Alshammari, Haya F Alzamami, Mona Ashoor, Wasan F Almarzouq, Haitham Kussaibi
Journal: Case Rep Otolaryngol (2019)
MeSH terms: Case Reports

Inflammatory myofibroblastic tumor (IMT) is a benign lesion that occurs most frequently in the soft tissues and viscera. In the head and neck region, the tumor has been reported to occur in the orbit, tongue, nasopharynx, larynx, and paranasal sinuses and the central nervous system. Despite being a benign lesion, it exhibits infiltrative and destructive behaviours, making histopathological examination necessary to confirm the diagnosis. We report the case of a 38-year-old female presented with a right nasolabial fold mass, which was confirmed histologically to be an IMT. Surgical excision of the mass was achieved through a sublabial approach with an uneventful postoperative period. To the best of our knowledge, this is the first reported case of an IMT in the nasolabial fold.
Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
Authors: Van Schloegel, Syed M Alam, Katie Dennis, Jeffrey Holzbeierlein, John A Taylor Iii
Journal: Case Rep Urol (2020)
MeSH terms: Case Reports

We report three cases of prostate adenocarcinoma appearing as bladder masses and misdiagnosed as muscle-invasive bladder cancer (MIBC). Patients were referred for consideration for radical cystectomy after initial pathological diagnosis suggested poorly differentiated bladder cancer. Pathological review of tissue samples and subsequent immunohistochemical (IHC) staining confirmed advanced prostatic adenocarcinoma. Systemic therapy for prostate cancer was then initiated. These cases highlight the importance of patient history, physical exam, and IHC staining in consideration of a bladder mass, as these patients may have been subject to undue morbidity and surgical intervention without accurate pathologic diagnosis.
Catatonia, neuroleptic malignant syndrome, and cotard syndrome in a 22-year-old woman: a case report
Authors: C Weiss, J Santander, R Torres
Journal: Case Rep Psychiatry (2013)

The following case study describes a 22-year-old woman with depression and symptoms of psychosis who developed neuroleptic malignant syndrome after using Risperidone, thus requiring life support equipment and Bromocriptine, later recovering after seven days. From a psychiatric and neurological point of view, however, the persistence of catatonic syndrome and Cotard syndrome delusions was observed, based on assertions such as "I do not have a heart," "my heart is not beating," "I can not breathe," "I am breaking apart," "I have no head" (ideas of negation) and statements about the patient being responsible for the "death of the whole world" (ideas of enormity). Brain NMR revealed leukoencephalopathy, interpreted as scar lesions caused by perinatal neurological damage, after discarding other pathologies. The patient responded well to electroconvulsive therapy after 11 sessions. Organic vulnerability to these syndromes, as well as their coexistence and clinical differentiation is discussed in the light of the data observed.
Kerion Celsi in a Nepalese Boy: An Underdiagnosed Cause of Scalp Swelling
Authors: Ranjana Parajuli, Ashish Lal Shrestha, Niranjan Nayak, Shishir Gokhale, Kundan Gautam, Shishir Subedi
Journal: Case Rep Infect Dis (2021)
MeSH terms: Case Reports

Tinea capitis (TC) is an infection of the scalp and hair caused by a dermatophyte fungus. Typically caused by the zoophilic and geophilic species of Microsporum and Trichophyton, it remains the commonest cutaneous fungal infection in children. A 9-year-old Nepalese boy was evaluated in outpatients for multiple boggy scalp lesions for two months. Suspecting a bacterial etiology, the lesions were excised and sent for cultures. While bacterial cultures failed to grow, endothrix spores were readily detected in potassium hydroxide preparation and histopathology. Trichophyton tonsurans was identiﬁed by the phenotype method and later conﬁrmed by matrix-assisted laser desorption ionization-time of ﬂight (MALDI-TOF). Systemic antifungal therapy for 6 weeks along with local wound dressings resulted in complete recovery. At 2-year follow-up, focal alopecia was seen; however, no recurrence was noted.
Ultrasound-Guided Subclavian Vein Cannulation in Neonate via Supraclavicular Approach
Authors: Onur Balaban, Tayfun Aydın
Journal: Case Rep Anesthesiol (2017)
MeSH terms: Case Reports

Central venous cannulation of infants may be challenging. Ultrasonography is recommended and has been found superior to classic landmark technique in pediatric central venous cannulation. The cannulation of the subclavian vein using supraclavicular approach under real-time ultrasound guidance is a novel technique. It may have advantages over ultrasound-guided jugular vein cannulation in specific patients. We report a case of 3200-gram 20-day-old anencephalic neonate who had a diffuse generalized edema. The neonate was cannulated successfully via subclavian vein using supraclavicular approach under ultrasound guidance.
Supraspinal and Afferent Signaling Facilitate Spinal Sensorimotor Network Excitability After Discomplete Spinal Cord Injury: A Case Report
Authors: Alena Militskova, Elvira Mukhametova, Elsa Fatykhova, Safar Sharifullin, Carlos A Cuellar, Jonathan S Calvert, Peter J Grahn, Tatiana Baltina, Igor Lavrov
Journal: Front Neurosci (2020)
Keywords: ais-a, discomplete spinal cord injury, spinal cord injury, spinal cord stimulation, sub-lesional spinal circuitry

Objective:
In this study, we evaluated the role of residual supraspinal and afferent signaling and their convergence on the sublesional spinal network in subject diagnosed with complete paralysis (AIS-A).
Methods:
A combination of electrophysiologic techniques with positional changes and subject-driven reinforcement maneuvers was implemented in this study. Electrical stimulation was applied transcutaneously at the T9-L2 vertebra levels and the spinal cord motor evoked potentials (SEMP) were recorded from leg muscles. To test the influence of positional changes, the subject was placed in (i) supine, (ii) upright with partial body weight bearing and (iii) vertically suspended without body weight bearing positions.
Results:
Increase in amplitude of SEMP was observed during transition from supine to upright position, supporting the role of sensory input in lumbosacral network excitability. Additionally, amplitudes of SEMP were facilitated during reinforcement maneuvers, indicating a supralesional influence on sub-lesional network. After initial assessment, subject underwent rehabilitation therapy with following electrophysiological testing that reviled facilitation of SEMP.
Conclusion:
These results demonstrate that combination of electrophysiological techniques with positional and reinforcement maneuvers can add to the diagnostics of discomplete SCI. These findings also support an idea that integration of supraspinal and afferent information on sub-lesional circuitry plays a critical role in facilitation of spinal sensorimotor network in discomplete SCI.
The properties of terrestrial laser system intensity for measuring leaf geometries: a case study with Conference Pear trees (Pyrus communis)
Authors: Mathilde A F Balduzzi, Dimitry Van der Zande, Jan Stuckens, Willem W Verstraeten, Pol Coppin
Journal: Sensors (Basel) (2011)
Keywords: ghost point, tls, conference pear tree, intensity return, leaf geometries, leaf inclination, mesh
MeSH terms: Lasers, Plant Leaves / anatomy & histology, Pyrus / anatomy & histology, Trees / anatomy & histology, Research Support, Non-U.S. Gov't, Least-Squares Analysis, Light, Plant Leaves / radiation effects, Pyrus / radiation effects, Reproducibility of Results, Trees / radiation effects

Light Detection and Ranging (LiDAR) technology can be a valuable tool for describing and quantifying vegetation structure. However, because of their size, extraction of leaf geometries remains complicated. In this study, the intensity data produced by the Terrestrial Laser System (TLS) FARO LS880 is corrected for the distance effect and its relationship with the angle of incidence between the laser beam and the surface of the leaf of a Conference Pear tree (Pyrus commmunis) is established. The results demonstrate that with only intensity, this relationship has a potential for determining the angle of incidence with the leaves surface with a precision of ±5° for an angle of incidence smaller than 60°, whereas it is more variable for an angle of incidence larger than 60°. It appears that TLS beam footprint, leaf curvatures and leaf wrinkles have an impact on the relationship between intensity and angle of incidence, though, this analysis shows that the intensity of scanned leaves has a potential to eliminate ghost points and to improve their meshing.
Managing Post COVID-19 Patient with Breathlessness
Authors: Yen Shen Wong, Muhammad Amin Ibrahim, Mohd Arif Mohd Zim, Mohd Fauzi Abdul Rani
Journal: Case Rep Med (2022)
MeSH terms: Case Reports

Background:
Chronic respiratory disease may be associated with severity of coronavirus disease 2019 (COVID-19) infection. We review a case of chronic obstructive pulmonary disease (COPD) patient who developed acute breathlessness post COVID-19 infection, also focusing on the diagnostic approach.
Case:
A 69-year-old gentleman with background history of COPD GOLD D and ischemic heart disease was admitted with severe COVID-19 infection. He required high-flow nasal cannula upon presentation. A computed tomography pulmonary angiography (CTPA) thorax at day 10 of illness revealed moderate organizing pneumonia (OP) with emphysematous changes, without pulmonary embolism. He received oral baricitinib and intravenous methylprednisolone for 3 days, which was then followed by tapering prednisolone starting dose of 1 mg/kg/day (60 mg/day) with reduction of 10 mg prednisolone every 3 days. COPD pharmacotherapy was optimized with early utilization of dual bronchodilators and inhaled corticosteroid was withheld. He underwent inpatient pulmonary rehabilitation and was discharged with home oxygen therapy. Unfortunately, he was re-admitted after 2 weeks with shortness of breath and fever for 3 days. Blood results revealed leucocytosis with raised C-reactive protein. A repeat CTPA showed increase reticulations and crazy paving pattern with reduction in lung volume. Multidisciplinary team discussion concluded it as interstitial pneumonia with COVID-19 OP and fibrosis progression. Prednisolone was stopped and he responded well with antibiotics. A follow-up at 3 months post COVID-19 infection showed improvement of clinical symptoms with radiological resolution of ground glass changes.
Conclusion:
Corticosteroid inhaler should be cautioned in this case, in view of recent pneumonia and non-elevated serum eosinophil count. These groups of patients should be closely followed up to unmask interstitial lung disease that may present prior to COVID-19 and worsen post-infection. Optimizing pre-existing medical conditions should be the paramount intervention.
The Impact of Hypomania on Aerobic Capacity and Cardiopulmonary Functioning-A Case Report
Authors: Aura Shoval, Hilary F Armstrong, Julia Vakhrusheva, Jacob S Ballon, Matthew N Bartels, David Kimhy
Journal: Front Psychiatry (2018)
Keywords: schizophrenia, aerobic fitness (vo2max), cardiopulmonar exercise testing, cardiopulmonary, cardiopulmonary activity, hypomania, mania and bipolar disorder
MeSH terms: Case Reports

Background: Hypomanic episodes are characterized by increased goal-directed behavior and psychomotor agitation. While the affective, cognitive, and behavioral manifestations of such episodes are well-documented, their physiological influence on aerobic capacity and cardiopulmonary functioning are unknown. Methods: We describe a case report of an individual with schizophrenia who experienced a hypomanic episode while serving as a control participant (wait list) in a single-blind, randomized clinical trial examining the impact of aerobic exercise (AE) on neurocognition in people schizophrenia. As part of the trial, participants completed two scheduled clinical assessments and cardiopulmonary exercise tests (VO2max) at baseline and 12 weeks later at end of study. All participants received standard psychiatric care during the trial. Following a baseline assessment in which he displayed no evidence of mood lability, the subject returned on Week-12 for his scheduled follow-up assessment displaying symptoms of hypomania. He was able to complete the follow-up assessment, as well as third assessment 2 weeks later (Week-14) when his hypomanic symptoms ebbed. Results: While not engaging in AE, the subject's aerobic capacity, as indexed by VO2max, increased by 33% from baseline to Week-12. In comparison, participants engaged in the aerobic exercise training increased their aerobic capacity on average by 18%. In contrast, participants in the control group displayed a small decline (-0.5%) in their VO2max scores. Moreover, the subject's aerobic capacity increased even further by Week-14 (49% increase from baseline), despite the ebbing of his hypomania symptoms at that time. These changes were accompanied by increases in markers of aerobic fitness including peak heart rate, respiratory exchange rate, peak minute ventilation, watts, and peak systolic blood pressure. Resting systolic and diastolic blood pressure, and peak diastolic blood pressure remained unchanged. Conclusions: Our findings suggest that hypomania produce substantial increase in aerobic capacity and that such elevations may remain sustained following the ebbing of hypomanic symptoms. Such elevations may be attributed to increased mobility and goal-directed behavior associated with hypomania, as individuals in hypomanic states may ambulate more frequently, for longer duration, and/or at higher intensity. Our results provide a first and unique view into the impact of hypomania on aerobic capacity and cardiopulmonary functioning.
The role of albumin in human toxicology of cobalt: contribution from a clinical case
Authors: Simona Catalani, Roberto Leone, Maria Cristina Rizzetti, Alessandro Padovani, Pietro Apostoli
Journal: ISRN Hematol (2011)

The distribution and adverse effects, especially to optic and acoustic nerves, of cobalt released from a hip arthroplasty and its association with albumin were studied. The analysis of cobalt was performed in plasma, whole blood, urine, and cerebrospinal fluid by inductively coupled plasma mass spectrometry (ICP-MS). The fraction of albumin binding the metal was determined by colorimetric assay using dithiothreitol (DTT). In all the biological matrices very high levels of cobalt were measured, but contrary to expected, a higher concentration in whole blood than in plasma was observed. The determination of altered albumin confirmed this hypothesis. This evidence might indicate an alteration in the binding of cobalt to albumin and a consequent increase in the concentration of the diffusible (free) fraction of the metal. This appears an interesting starting point for further investigations for identifying and better understanding cobalt neurotoxicity, apparently not so frequent in occupational medicine and clinical practice.
Laser therapy in the treatment of feline sporotrichosis: A case series
Authors: Daniella Souther Carvalho Ribeiro, Luana Jordão Machado, Jéssica Gomes Pereira, Andrea Regina de Souza Baptista, Elisabeth Martins da Silva da Rocha
Journal: Braz J Vet Med (2023)
Keywords: sporothrix brasiliensis, alternative therapy, laser, mycosis
MeSH terms: Case Reports

Sporotrichosis is the most prevalent subcutaneous mycosis in Latin America and is an important zoonosis in expansion throughout all the brazilian territory. Domestic cats are highly susceptible to the disease and play an important role in the spread of the agent to both other animals and humans. Sporothrix brasiliensis, the predominant species in the country, has greater virulence and some isolates also showed resistance to azoles, the class of antifungals of choice for treatment. Because it is a long-duration treatment, of high cost, and oral use, sick animals are often abandoned, which contributes to the spread and permanence of the infection as an important public health problem. Therefore, new therapeutic alternatives or adjuncts to treatment with antifungals may contribute to combating this zoonotic agent. In this work we describe the result of the treatment with laser therapy of eight Sporothrix spp infected cats. Our findings show the efficacy of the laser treatment even in different clinical forms. This technique has the potential to decrease the time length and costs of conventional treatment as well as the improvement of the treatment results.
Uterine Rupture in Pregnancy following Fall from a Motorcycle: A Horrid Accident in Pregnancy-A Case Report and Review of the Literature
Authors: Wondimagegnehu Sisay Woldeyes, Demisew Amenu, Hailemariam Segni
Journal: Case Rep Obstet Gynecol (2015)

Uterine rupture is one of the most catastrophic complications during pregnancy. It is a rare complication in developed countries but a frequent cause of maternal and perinatal morbidity and mortality in Africa. Uterine rupture occurs in 1.6% of patients suffering blunt abdominal trauma. Here we report a unique case of complete fundal rupture of the unscarred uterus following fall from motorcycle in 39-week-pregnant mother who was managed with total abdominal hysterectomy and left salpingo-oophorectomy and survived, though fetus died before intervention. We also reviewed similar cases reported from different parts of Africa. This is a preventable complication had the woman been properly instructed on transportation safety during her antenatal care visits.
Orbital Infection by Saksenaea vasiformis in an Immunocompetent Host
Authors: Mingkwan Lumyongsatien, Pimkwan Jaru-Ampornpan, Mongkol Uiprasertkul, Dinesh Selva
Journal: Case Rep Ophthalmol Med (2020)
MeSH terms: Case Reports

Orbital mucormycosis caused by Saksenaea vasiformis is extremely rare. Herein, we report an immunocompetent 22-year-old Thai female who presented with two months of progressive right upper eyelid mass, associated with swelling, redness, and ptosis. She failed to improve despite multiple courses of antibiotic and steroid treatment. Computed tomography (CT) scan showed infiltration involving the upper eyelid and lacrimal gland. Fungal hyphae were revealed by histopathological study. Polymerase chain reaction (PCR) was positive for Saksenaea vasiformis (GenBank: accession number FR687327.1). The patient was successfully treated with surgical debridement, amphotericin B, and oral posaconazole.
Histopathological Characterization of a Series of Oral Basaloid Squamous Cell Carcinoma
Authors: Neetu Jain, Toniya Raut, Shashi Keshwar, Ashish Shrestha, Mehul Rajesh Jaisani, Deepak Paudel
Journal: Case Rep Dent (2023)
MeSH terms: Case Reports

Basaloid squamous cell carcinoma (BSCC) is a rare, distinctive, and aggressive variant of squamous cell carcinoma (SCC) primarily seen in the upper aerodigestive tract with epiglottis, soft palate, and base of the tongue being site of high preference in head and neck region. It differs from conventional SCC histologically and immunologically, is most frequently found in males in their sixth and seventh decades, and is frequently linked to alcohol and tobacco use. High stage disease with distant metastases, a high recurrence rate, and a dismal prognosis is how BSCC typically manifests. In the present article, we report four cases of BSCC.
A New Way Out of the Predicament of Anaplastic Thyroid Carcinoma From Existing Data Analysis
Authors: Yikun Zhou, Yang Zhao, Xi Ding, Jing Liang, Huayang Xu, Yuxuan Lin, Hamad Haider Khan, Bingyin Shi
Journal: Front Endocrinol (Lausanne) (2022)
Keywords: anaplastic thyroid carcinoma (atc), early diagnosis, long-term survival, radical surgery, radiotherapy
MeSH terms: Thyroid Carcinoma, Anaplastic / drug therapy, Thyroid Neoplasms / pathology, Case Reports, Research Support, Non-U.S. Gov't, Aged, 80 and over, Data Analysis, Female, Humans, Incidence, Prognosis

Background:
Anaplastic thyroid carcinoma (ATC) is an endocrine tumor with a low incidence but a very poor prognosis. The vast majority of patients have a survival time of only three to six months, but a few survive for two years or more. In recent years, there have been major breakthroughs in targeted and immunotherapy in the field of oncology therapy. Although the preliminary study for ATC showed a promising prospect, more clinical trials are needed. It is the best approach to explore the measures that can improve survival time of ATC from the available clinical data, especially those with long survival.
Methods:
We report on an 82-year-old ATC patient who survived for 3 years and systematically review the clinical characteristics of 45 ATC patients with complete data from the two largest centers in northwest China. In particular, factors related to long-term survival were analyzed and summarized.
Results:
Three years prior, an 82-year-old woman was diagnosed with ATC by core needle biopsy following a physical examination. The thyroid tumor was resected within one month, and then the patient was treated with radiotherapy. The patient was still healthy after three years of follow-up. Analysis of prognostic factors for the 45 reviewed patients showed that those undergoing radical surgery (median overall survival (OS) = 472 days, p = 0.0261) and radiotherapy (median OS = 220 days, p = 0.0136) had better outcomes. In addition, patients younger than 65 years (median OS = 164.5 days, p = 0.0176) and with a lower tumor stage (IV A, median OS = 633.5 days, p = 0.0191) also had a better outcome.
Conclusion:
ATC is a highly malignant tumor, but timely early diagnosis and standardized treatment with radical surgery and radiotherapy as the core can achieve good results. Some patients can achieve long-term survival.
Utility of endometrial sampling prior to risk-reducing hysterectomy in a patient with Lynch syndrome
Authors: Melissa K Frey, Gizelka David-West, Khushbakhat R Mittal, Franco M Muggia, Bhavana Pothuri
Journal: Ecancermedicalscience (2016)
Keywords: colorectal neoplasms, endometrial neoplasms, hereditary nonpolyposis, hysterectomy, risk reduction surgery, uterine neoplasms
MeSH terms: Case Reports

Occult endometrial cancer is occasionally discovered in women with Lynch syndrome undergoing risk-reducing hysterectomy. The case presented here demonstrates that preoperative endometrial sampling can help detect these occult cancers; however, there are currently no recommendations for this preoperative intervention. A 50-year-old woman with Lynch syndrome underwent endometrial sampling prior to planned risk-reducing hysterectomy and bilateral salpingo-oophorectomy. The endometrial biopsy demonstrated a serous endometrial cancer. The patient was counselled regarding the diagnosis and revised operative plan, which now included staging, prior to surgery. Although the prevalence of occult endometrial cancer at the time of risk-reducing surgery in women with Lynch syndrome remains unknown, preoperative endometrial sampling may allow for improved patient counselling and surgical planning in this population, and can help avoid a subsequent surgery for staging.