OpenMed/multicare-articles huggingface dataset:
Successful Outcome After Intralesional Curettage for Spindle Cell Hemangioma of Fibula in an Infant: A Case Report
Authors: Tao Han, Rufa Wang, Xiaoguang Zhou
Journal: Front Pediatr (2021)
Keywords: fibula, intralesional curettage, outcome, spindle cell hemangioma, vascular lesions
MeSH terms: Case Reports

Spindle cell hemangioma (SCH), a non-neoplastic reactive vascular lesion, rarely locates in bones. We herein report a successful case of intralesional curettage for an infant with SCH of fibula. An 11-month-old boy was admitted to our center with a painless mass in the right proximal calf. Preoperative digital radiograph demonstrated a massive vascular lesion with an irregular bone destruction of proximal fibula. The lesion was removed via the intralesional curettage approach and pathologically diagnosed as SCH. The patient gained bone structure recovery of right proximal fibula. Two years after the surgery, he experienced no local recurrence. For the management of SCH of fibula with partial bone destruction, we suggest early-stage intralesional curettage as its safety and effectiveness.
Optic disc melanocytoma: a case report
Authors: Giran Mannat, Sindhu Meenakshi, Naveen Kalra Navya, Narang Subina
Journal: Rom J Ophthalmol (2021)
Keywords: benign ocular lesion, choroidal melanoma, melanocytoma
MeSH terms: Melanoma / diagnosis, Optic Disk / pathology, Optic Nerve Neoplasms / diagnosis, Case Reports, Adult, Biopsy, Fluorescein Angiography, Fundus Oculi, Humans, Male

Often misdiagnosed as melanoma, melanocytoma of the optic disc is a rare benign ocular lesion that requires minimal active intervention, but demands a life time follow-up. We present a case of a 32-year-old man who was referred to our institute for the management of choroidal melanoma of the optic disc, which was detected by chance when the patient presented to a general ophthalmologist with chief complaint of itching in both eyes. The patient had normal visual acuity and fundoscopy revealed classical optic disc melanocytoma. The ancillary tests confirmed the diagnosis. The patient was kept under follow-up for four years, which showed no increase in size of the lesion. The purpose of this presentation was to highlight the identifying features of ocular melanocytoma and differentiate it from other conditions requiring urgent intervention.
Case Report: Virtual and Interactive 3D Vascular Reconstruction Before Planned Pancreatic Head Resection and Complex Vascular Anatomy: A Bench-To-Bedside Transfer of New Visualization Techniques in Pancreatic Surgery
Authors: Robert Templin, Navid Tabriz, Martin Hoffmann, Verena Nicole Uslar, Thomas Lück, Andrea Schenk, Rainer Malaka, Gabriel Zachmann, Alexander Kluge, Dirk Weyhe
Journal: Front Surg (2020)
Keywords: 3d-printing, bühler anastomosis, augmented reality, digitization, pancreas, virtual reality
MeSH terms: Case Reports

Introduction: Bühler's anastomosis (or Bühler's arcade) is an embryonic relic and represents an arterio-arterial connection between the superior mesenteric artery and the celiac trunk. It can be found as a variety in 1-2% of patients. Case Presentation: We present a case of a patient with metatastatic squamous cell carcinoma of the lung. The patient was in stable disease for 4 years under palliative therapy (most recently second-line therapy with Nevolumab). In 2019, a locally advanced adenocarcinoma of the papilla vateri was diagnosed, additionally. The patient also underwent right hemicolectomy and patch plasty of the celiac trunk and superior mesenteric artery due to colonic ischemia and arteriosclerotic disease with 50-70% stenosis of the superior mesenteric artery several years ago. Due to a complex vascular prehistory, the standardized preoperative imaging was supplemented by two independent vascular reconstructions (a CT angiogram and a reconstruction based on the CT) for the planning of a pylorus-preserving pancreatic head resection and reconstruction according to Traverso-Longmire. In addition, a 3D print was produced. Both, the reconstruction based on the CT scan and the 3D print were created for off-label use as a part of a research project (VIVATOP: Versatile Immersive Virtual and Augmented Tangible OP). Discussion: In the standardized CT scan and in the clinical CT-angiography, there were no obvious surgically relevant anatomical variations. A Bühler anastomosis was detected in a digital, virtual and interactive 3D-reconstruction. In addition, in the 3D print of the abdominal site the anastomosis was seen as well. Intraoperatively, the presence of Bühler's anastomosis was confirmed. This information had a significant impact on the intraoperative approach. Retrospectively, the vessel variant could be surmised in the axial projection of the CT scan, if one knew what to look for. Conclusion: For the conduction of a safe surgical procedure, it is imperative that rare anatomical variations are known preoperatively. Increasing digitalization in surgical and perioperative preparation holds great potential for better planning and improved patient safety. Research and cooperation projects such as the VIVATOP project are instrumental for the development of new visualization techniques, which are able to enhance the understanding of complex anatomical relations.
Hereditary spastic paraplegia (SPG 48) with deafness and azoospermia: A case report
Authors: Ping Jin, Yu Wang, Na Nian, Gong-Qiang Wang, Xiao-Ming Fu
Journal: Front Neurol (2023)
Keywords: ap5z1 gene mutation, spg48, azoospermia, brain mri, impaired hearing
MeSH terms: Case Reports

Hereditary spastic paraplegias (HSP) are inherited neurodegenerative disorders characterized by progressive paraplegia and spasticity in the lower limbs. SPG48 represents a rare genotype characterized by mutations in AP5Z1, a gene playing a role in intracellular membrane trafficking. This study describes a case of a 53-year-old male patient with SPG48 presenting spastic paraplegia, infertility, hearing impairment, cognitive abnormalities and peripheral neuropathy. The Sanger sequencing revealed a homozygous deletion in the chr 7:4785904-4786677 region causing a premature stop codon in exon 10. The patient's brother was heterozygous for the mutation. The brain magnetic resonance imaging found a mild brain atrophy and white matter lesions. In the analysis of the auditory thresholds, we found a significant hearing decrease in both ears.
Thrombotic microangiopathy secondary to recurrent prostate cancer
Authors: Joseph Newton, Lauren Floyd, Arvind Ponnusamy, John Anderton
Journal: Clin Nephrol Case Stud (2021)
Keywords: acute kidney injury, eculizumab, hemolytic uremic syndrome, thrombotic microangiopathy
MeSH terms: Case Reports

An 86-year-old man returned to the UK from Spain with symptoms suggestive of gastrointestinal bleeding. He was found to have an acute kidney injury and thrombocytopenia. Further investigations identified the presence of a microangiopathic hemolytic anemia, supporting the diagnosis of a thrombotic microangiopathy. Differentials included atypical hemolytic uremic syndrome and secondary thrombotic microangiopathy. Thrombotic thrombocytopenic purpura (TTP) and STEC (Shiga toxin-producing E. coli) hemolytic uremic syndrome were excluded by a normal ADAMTS-13 and negative E. coli serology and stool PCR. The patient was treated with blood and platelet transfusions. He received eculizumab and hemodialysis whilst a screen for secondary causes was undertaken. Thrombotic microangiopathy was shown to be secondary to recurrence of prostate cancer, which had been treated 16 years previously. He later recovered his renal function and receives ongoing hormonal treatment for his prostate cancer.
Incorporating electrical impedance tomography to transpulmonary pressure-guided PEEP in severe ARDS with pneumothorax and multiple cavitations: a case report
Authors: Qianling Wang, Longxiang Su, Jing Jiang, Na Wang, Huaiwu He, Yun Long
Journal: Front Med (Lausanne) (2023)
Keywords: ards, eit, mrsa pneumonia, positive end-expiratory pressure, transpulmonary pressure
MeSH terms: Case Reports

Pneumothorax is a potentially fatal complication in patients with acute respiratory distress syndrome (ARDS), presenting challenges in determining the optimal positive end-expiratory pressure (PEEP) level to prevent atelectasis without exacerbating the pneumothorax. This case report describes the successful application of transpulmonary pressure and electrical impedance tomography (EIT) at the bedside to guide PEEP selection in a patient with ARDS complicated by pneumothorax due to methicillin-resistant Staphylococcus aureus infection. By using minimal PEEP to maintain positive end-expiratory transpulmonary pressure and visualizing lung reopening with EIT, the optimal PEEP level was reaffirmed, even if traditionally considered high. The patient's condition improved, and successful weaning from the ventilator was achieved, leading to a transfer out of the intensive care unit. Clinical trial registration: https://clinicaltrials.gov/show/NCT04081142, identifier NCT04081142.
Mandibular reconstruction using single piece zygomatic implant in conjunction with a reinforcing Fibular Graft Union: A case report
Authors: Vivek Gaur, Anita Gala Doshi, Lukasz R Palka
Journal: Int J Surg Case Rep (2020)
Keywords: immediate loading, mucosalization, single piece bicortical implant, zygomatic implant
MeSH terms: Case Reports

Presenting to our knowledge, for the first time in literature, a case report on the long term follow-up of an implant retained fixed prosthesis on free fibular reconstruction with a single piece zygomatic implant and single piece bicortical implant via a flapless approach and immediate functional rehabilitation. The technique involved the concept of "Remote Bone Anchorage" in conjunction with the union of grafted free fibula flap with the native mandible. It was facilitated with a single piece zygomatic implant engaged in the mandible and splinted with single piece implants on the grafted fibula as needed for prosthetic functional reconstruction. The author has reported a unique concept of immediate functional rehabilitation in the fibular graft therefore providing additional splinting of the vascularized free fibula to the mandible by splinting them with single piece zygomatic cortical implant.
Vasogenic Cerebral Edema following CT Myelogram with Nonionic Omnipaque 300
Authors: Sara Khodor, Scott Blumenthal
Journal: Case Rep Neurol Med (2018)
MeSH terms: Case Reports

Computed Tomography (CT) with myelogram is a relatively safe procedure. It requires the use of nonionic contrast agents which, unlike ionic contrast agents, have been associated with low complication rates. We report a case of a 69-year-old female who developed diffuse bilateral cerebral edema following a lumber myelogram with the use of intrathecal nonionic contrast agent Omnipaque (Iohexol) 300. We were able to find one other reported case of cerebral edema following the use of intrathecal nonionic contrast agent in the literature.
Severe COVID-19-Induced Hemophagocytic Lymphohistiocytosis
Authors: Shahkar Khan, Taqi A Rizvi, Waleed Sadiq, Saud Bin Abdul Sattar, Rabih Maroun
Journal: Cureus (2023)
Keywords: acute hypoxic respiratory failure, coronavirus disease 2019, covid 19, cytokine storm syndrome, hemophagocytic lymphohistiocytosis (hlh), multiorgan system failure
MeSH terms: Case Reports

We reported a case of secondary hemophagocytic lymphohistiocytosis (HLH), a rare and life-threatening condition, which was suspected to have been triggered by a severe case of coronavirus disease 2019 (COVID-19). A 50-year-old man with a past medical history of ulcerative colitis with recent pancolitis status post colectomy and ileostomy two weeks before presentation presented to the emergency department with one week of subjective fevers, weakness, watery diarrhea, and decreased oral intake. A CT scan showed fluid in the rectum and post-surgical changes from his recent colectomy along with diffuse reticulonodular opacities of the lungs. His COVID-19 reverse transcriptase-polymerase chain reaction (RT-PCR) test was positive. Over the subsequent days, the patient's condition worsened as he developed worsening acute hypoxic respiratory failure with diffuse lymphadenopathy, splenomegaly, worsening cytopenias, and increased ferritin of >100,000 ng/ml on hospital day six. Hematology oncology was consulted and he was started on empiric steroid therapy followed by etoposide. However, his condition continued to worsen, and eventually, the patient passed away on hospital day eight.
Procedure-Related Complication of Willis Covered Stent in the Treatment of Blood Blister-Like Aneurysm: Stent Detachment from Dilating Balloon
Authors: Yuxiang Zhang, Yupeng Zhang, Fei Liang, Chuhan Jiang
Journal: Front Neurol (2017)
Keywords: willis covered stent, blister-like aneurysm, complication, stent detachment, tortuosity of the internal carotid artery
MeSH terms: Case Reports

The use of Willis covered stent (WCS) for intracranial aneurysms has increased based on the promising results of previous studies about its safety and effectiveness. With the accumulation of cases, reports about peri-procedural complications are emerging. In our department, 25 patients were treated with WCS during December 2015 to March 2017. We here reported an unexpected technical complication occurred in the treatment with the WCS for a blood blister-like aneurysm (BBA). During the procedure, the distal end of the stents detached from the dilating balloon partially or as a whole. This was attributed to the tortuosity of the access route and the extracorporeal gas exhaust maneuver. Then we applied a half-dilating technique to retrieve the detached stent. The procedures were detailed in this report and the possible reasons and approaches to avoid it were explored.
Case report: Emapalumab for active disease control prior to hematopoietic stem cell transplantation in refractory systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome
Authors: Deepak Chellapandian, Diana Milojevic
Journal: Front Pediatr (2023)
Keywords: allogeneic hematopoietic stem cell transplantation, case report, emapalumab, macrophage activation syndrome (mas), systemic juvenile idiopathic arthritis (sjia)
MeSH terms: Case Reports

Introduction:
Macrophage activation syndrome (MAS), a secondary form of hemophagocytic lymphohistiocytosis, is a serious life-threatening complication associated with systemic juvenile idiopathic arthritis (sJIA). MAS is characterized by fever, hepatosplenomegaly, liver dysfunction, cytopenias, coagulation abnormalities, and hyperferritinemia and may progress to multiple organ failure and death. Overproduction of interferon-gamma is a major driver of hyperinflammation in murine models of MAS and primary hemophagocytic lymphohistiocytosis. A subset of patients with sJIA may develop progressive interstitial lung disease, which is often difficult to manage. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) can potentially be a curative immunomodulatory strategy for patients with sJIA refractory to conventional therapy and/or complicated by MAS. The use of emapalumab (anti-interferon gamma antibody) for the active control of MAS in refractory cases of sJIA and associated lung disease has not been reported. Herein we report a patient with refractory sJIA complicated by recurrent MAS and lung disease that was managed with emapalumab and ultimately followed by an allo-HSCT, which resulted in permanent correction of the underlying immune dysregulation and improvement of lung disease.
Case report:
We present a 4-year-old girl with sJIA complicated by recurrent MAS and progressive interstitial lung disease. She developed a progressively worsening disease that was refractory to glucocorticoids, anakinra, methotrexate, tocilizumab, and canakinumab. She had a chronic elevation of serum inflammatory markers, notably soluble interleukin-18, and CXC chemokine ligand 9 (CXCL9). Emapalumab, initiated at 6 mg/kg (1 dose) and continued at 3 mg/kg twice weekly for a total of 4 weeks, resulted in MAS remission along with normalization of inflammatory markers. The patient received a matched sibling donor allo-HSCT after a reduced-intensity conditioning regimen with fludarabine/melphalan/thiotepa and alemtuzumab, along with tacrolimus and mycophenolate mofetil for graft-vs.-host disease prophylaxis. At 20 months following her transplant, she has maintained a full donor engraftment with complete donor-derived immune reconstitution. She had complete resolution of sJIA symptoms including marked improvement in her lung disease along with normalization of serum interleukin-18 and CXCL9 levels.
Conclusion:
The use of emapalumab followed by allo-HSCT could help achieve a complete response in refractory cases of sJIA complicated by MAS who have failed standard treatment.
Ruthenium-106 plaque therapy for diffuse choroidal hemangioma in sturge-weber syndrome
Authors: Agnieszka Kubicka-Trząska, Joanna Kobylarz, Bożena Romanowska-Dixon
Journal: Case Rep Ophthalmol Med (2011)
MeSH terms: Case Reports

Diffuse choroidal hemangiomas associated with Sturge-Weber syndrome (SWS) are classically treated with external beam radiotherapy (EBR), but there are a few reports usually of single cases indicating the usefulness of plaque therapy. We present our observations on two cases of diffuse choroidal hemangiomas with exudative retinal detachment associated with SWS treated with Ruthenium-106 plaque therapy. Outcomes included best-corrected visual acuity (BCVA) and regression in tumor thickness measured by ultrasonography. The initial BCVA of the affected eyes was counting fingers at 1 meter and light projection. Pretreatment tumors thickness was 3.5 mm and 4.7 mm. In a follow-up period of 18-24 months, significant reduction in thickness of choroidal hemangiomas up to 1.2 mm and 1.4 mm with prompt resolution of exudative retinal detachment was observed. BCVA achieved 20/200 and 20/400, respectively. The findings in this paper indicate that Ruthenium-106 plaque therapy is effective in treatment of diffuse choroidal hemangiomas associated with SWS.
Combined Orthodontic and Surgical Management for Treatment of Severe Class III Malocclusion with Anterior and Posterior Crossbites
Authors: Yahya A Alogaibi, Fahad F Alsulaimani, Basem Jamal, Rania Mitwally
Journal: Case Rep Dent (2021)
MeSH terms: Case Reports

Severe class III malocclusion can be a great challenge, especially in adult patients. This case report describes an adult patient with severe skeletal class III malocclusion and with an obvious maxillary deficiency and mandibular excess causing both anterior and posterior crossbites in addition to a shift in the upper and lower midlines to the left concerning the facial midline. This was complicated by compensatory mechanisms such as the proclination of upper incisors and retroclination of lower incisors. Decompensation of the upper and lower arches was performed combined with upper arch expansion to relieve crowding in the upper arch and correct the posterior crossbite. This was followed by double jaw surgeries, including Le Fort I osteotomy in the maxilla and bilateral sagittal split osteotomy (BSSO) in the mandible. Orthodontic finishing procedures were then used to correct any other dental discrepancies. Remarkable esthetic and functional results were achieved with high patient satisfaction.
Acute oxalate nephropathy associated with orlistat: a case report with a review of the literature
Authors: Dhara Chaudhari, Conchitina Crisostomo, Charles Ganote, George Youngberg
Journal: Case Rep Nephrol (2013)

Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat. Herein we report a patient presenting with acute renal failure which improved minimal with intravenous hydration. She was found to have oxalate crystals on renal biopsy. Patient admitted orlistat use over the counter for weight reduction on further questioning. The purpose of this case review is to increase awareness among patients since they are more focused on losing weight. This case also calls for the provider attention to educate patients regarding side effects of orlistat because of easy availability of orlistat over the counter.
Case report and literature review: Giant retroperitoneal cystic lymphangioma
Authors: Tieshan Su, Chaoyuan Li, Bin Song, Defeng Song, Ye Feng
Journal: Front Surg (2023)
Keywords: case report, cystic lymphangioma, literature review, retroperitoneal tumor, surgical resection
MeSH terms: Case Reports

Background:
Cystic lymphangioma is a rare benign tumor of the lymphatic system, which is most commonly observed in the neck, head and armpit.Less than 5% of lymphangiomas occur in the abdominal cavity and even less in the retroperitoneum.
Case description:
A 65-year-old male patient was diagnosed with an "abdominal mass that had persisted for 1 year, accompanied by abdominal pain, abdominal distension and dyspnea for 7 days". After abdominal computerd tomography, a giant multilobed abdominal lymphangioma was suspected, which squeezed the intestinal canal and was closely related to the inferior vena cava. The patient underwent an exploratory laparotomy, during which, it was found that the tumor formed extensive adhesions to the transverse colon, small intestine and pelvic wall, and enveloped the abdominal aorta, superior mesenteric artery, inferior mesenteric artery and inferior vena cava to varying degrees. It was diffcult to remove the cyst completely. Postoperative pathology confirmed the diagnosis of retroperitoneal cystic lymphangioma. The patient recovered well after the operation, was eating normally by 5 days postoperatively,and was discharged 10 days postoperatively.The patient was followed up 1 month after postoperatively and no evidence of recurrence was observed.
Conclusion:
In this case, we report a patient with giant retroperitoneal cystic lymphangioma who underwent exploratory laparotomy combined with preoperative abdominal computerd tomography and acute abdominal pain, abdominal distension and dyspnea. Because of the large volume of the tumor and its close relationship with the superior mesenteric artery and other blood vessels, the surgeon used scissors to separate the tumor sharply and removed the whole tumor completely.
MR imaging findings of metastatic hepatocellular carcinoma in the nasal cavity: a rare site of spread
Authors: Dong Hyeok Kang, Sang Woo Shim, Su Jin Koh, Jung Gwon Nam, Young Min Kim, Young Cheol Weon
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

We here report an extremely rare case of metastatic hepatocellular carcinoma to the nasal cavity only with MRI scan including diffusion-weighted imaging and a brief review of previous literature case reports.
Case report: Single-operator peroral cholangioscopy system (SpyGlass) diagnosis of an extrahepatic biliary cystadenoma (video)
Authors: Xin Deng, Jingwen Wang, Tong Mou, Long Pan, Chengyou Du, Qiao Wu
Journal: Front Med (Lausanne) (2023)
Keywords: ercp, spyglass, biliary cystadenoma, cholangioscopy, indeterminate strictures
MeSH terms: Case Reports

Biliary cystadenoma is a type of rare liver cystic tumor. Intrahepatic biliary cystadenomas are the most common, while extrahepatic biliary cystadenomas are rarely seen. Biliary cystadenoma tends to occur in middle-aged to older women and there is a lack of specific preoperative diagnostic markers. Recent advancements in technology and the development of the SpyGlass system have led to an increased use of cholangioscopy. Herein, we report a patient in whom a space-occupying lesion was found in the bile duct by SpyGlass, and who later underwent radical surgery. The pathology report indicated that the final diagnosis was biliary cystadenoma. SpyGlass cholangioscopy may be a novel and effective diagnostic method for biliary cystadenoma.