OpenMed/multicare-articles huggingface dataset:
Impact of SARS-Con-V2 on the Poultry Industry in Kuwait: A Case Study
Authors: Hanan Al-Khalaifah, Afaf Al-Nasser, Noura Abdulmalek, Hamad Al-Mansour, Abdulaziz Ahmed, Gehan Ragheb
Journal: Front Vet Sci (2020)
Keywords: kuwait, sars-con-v2, crisis, curfew, poultry industry

The SARS-Con-V2 crisis influenced all aspects of life in the country including academics, economics, medical, and other fields. Poultry industry, whether locally or globally, is one of the investment fields that has been affected by the current SARS-Con-V2 crisis. As part of this global world, the local poultry companies in Kuwait have been impacted by restricting movements and transportation of the employees in between the company branches, exportation and importation of goods, bank closures, rise in the imported and local vaccination and drug prices, sales and marketing. The current case study paper sheds light on the impact of the current SARS-Con-V2 crisis on the local poultry industry, as well as the challenges and gaps in the local poultry value chain. It also propose solutions to mitigate this impact and to enhance sustainability of poultry products during other future global or local crisis.
A technique for non-deflating balloon catheter removal in female patients
Authors: Eirini Giovannopoulou, Kostas Chondros
Journal: Pan Afr Med J (2017)
Keywords: non-deflating balloon, balloon puncture, catheter removal, catheter retention
MeSH terms: Catheters, Indwelling, Device Removal / methods, Urinary Catheterization, Case Reports, Aged, Ambulatory Care / methods, Female, Humans

Removing a foley catheter can sometimes be a challenge, especially when it is related to non-deflating balloons which represent most of the cases. In female patients, due to their urethral anatomy, several techniques have been proposed for balloon puncture when other maneuvers have failed. We present a simple technique for non-deflating balloon catheter removal in an old female patient with a permanent indwelling foley catheter which required no anesthesia. The balloon was effectively punctured with minimal patient's discomfort. In addition, this technique was tested in several ex-vivo model catheters and found to be safe and effective. Our technique can be used for non-deflating balloon puncture in female patients in an outpatient setting without anesthesia.
Cardiogenic Shock: An Unusual Initial Presentation of Churg-Strauss Syndrome
Authors: M Apirami, J A Pratheepan, T Kumanan, M Guruparan, G Selvaratnam
Journal: Case Rep Rheumatol (2018)
MeSH terms: Case Reports

Churg-Strauss syndrome (CSS) is a rare autoimmune condition, characterized by necrotizing extravascular eosinophil rich granulomatous inflammation of the tissues and disseminated small-medium sized vessel vasculitis in a patient with bronchial asthma and tissue eosinophilia. Though pulmonary involvement is the predominant feature of CSS, extra pulmonary involvement, in particular, cardiac involvement, denotes an adverse outcome. Here we report a 50-year-old female who presented with cardiogenic shock due to an acute coronary event as the initial manifestation of CSS. A subsequent coronary angiogram revealed normal epicardial coronaries. She was a patient with bronchial asthma and developed vasculitic rash, bilateral sensory motor polyneuropathy, and migratory peripheral lung field shadows in the background of peripheral eosinophilia during the course of the illness. She was diagnosed as having CSS based on ACR criteria and aggressively treated with immunosuppressants according to her Five-Factor Score and has shown prompt response to therapy. This case report adds to the literature another rare initial presentation of CSS to the existing array of its clinical manifestations.
Double J stent malposition in the inferior vena cava: Two case reports and a literature review
Authors: Qihua Wang, Chen Shen, Yue Zhang, Lijie Wen, Bo Yang
Journal: Front Surg (2022)
Keywords: complication, double j stent, intravascular migration, malposition, treatment
MeSH terms: Case Reports

Double J stent (DJS) malposition in the vascular system is a rare and severe complication. We present two cases in our department who went through DJS malposition in the inferior vena cava and our experience in treatment, and we reviewed the previous case reports to further summarize its underlying reasons and prevention and treatment methods.
The great mimicker: zona zoster at the mastectomy site causing contralateral intramammary lymph node enlargement
Authors: Umit Aksoy Ozcan, Evrim Tezcanli, Yesim Yildirim, Melahat Garipagaoglu
Journal: Case Rep Oncol Med (2012)
MeSH terms: Case Reports

Zona zoster is rarely observed in patients with malignancy; when present, it follows a dermatomal fashion. Involvement of widely separated regions is very rare. Hereby, zona zoster causing enlarged intramammary lymph nodes (IMLN) in the opposite breast is reported for the first time in literature. The masses were hypoechoic on US with no hilum and hypervascular on color Doppler US. MRI showed hypointense masses with type 3 time-intensity curve and adjacent vessel sign. The complete regression of the nodes after the antiviral therapy confirmed the diagnosis. In breast cancer patients, IMLN enlargements may mimic breast cancer metastasis, and zona zoster infection of the mastectomy site may present with contralateral IMLN enlargement due to altered lymphatic drainage. When breast US is not sufficient for the differential diagnosis, breast MRI may warrant proper diagnosis, and prevent unnecessary biopsies. Antiviral treatment with followup would be sufficient for management.
Case Report: Complete Maternal Uniparental Disomy of Chromosome 2 With a Novel UNC80 Splicing Variant c.5609-4G> A in a Chinese Patient With Infantile Hypotonia With Psychomotor Retardation and Characteristic Facies 2
Authors: Yilun Tao, Dong Han, Yiju Wei, Lihong Wang, Wenxia Song, Xiaoze Li
Journal: Front Genet (2021)
Keywords: snp array, unc80 gene, chromosome 2, maternal uniparental disomy, whole exome sequencing
MeSH terms: Case Reports

Background: Infantile hypotonia with psychomotor retardation and characteristic facies 2 (IHPRF2) is a rare autosomal recessive neurodevelopmental disorder caused by mutations in the UNC80 gene. It is characterized by severe global developmental delay, poor or absent speech and absent or limited walking abilities. The current study explored a case of a Chinese patient with IHPRF2 caused by a novel splicing variant of UNC80. Case Report: The proband is a 8-year-old Chinese male manifested with global developmental delay, severe truncal hypotonia, absent speech and intellectual disability. SNP array analysis revealed a uniparental isodisomy of the entire chromosome 2 [UPD(2)] in the proband. Whole exome sequencing (WES) subsequently identified a novel mutation c.5609-4G>A in the UNC80 gene, which was inherited from his mother and was confirmed by Sanger sequencing, indicating that UPD(2) was of maternal origin. Conclusion: A novel UNC80 homozygous splicing variant c.5609-4G>A associated with maternal UPD(2) was identified. These findings indicate that UPD poses a high risk of autosomal recessive diseases, and provides information on the variant spectrum for UNC80. Our findings elucidate on understanding of the genotype-phenotype associations that occur in IHPRF2 patients.
Approach to Ankle Instability in Patients With a Negative Ankle MRI: A Case Series
Authors: Waleed K Alnejadi, Ammar Aljefri, Ziyad M Alharbi, Saif Saif, Kenan Nejaim, Mohammed Almutairi, Omar Batouk
Journal: Cureus (2023)
Keywords: ankle instability, anterior talofibular, calcaneo-fibular, normal mri, posterior talofibular ligament

Objectives Injuries to the ankle ligaments are some of the most common musculoskeletal sports injuries. Ankle magnetic resonance imaging (MRI) is the standard diagnostic procedure in today's practice, but its reliability and validity remain controversial. The aim of this study was to explore the approach for patients with negative ankle MRI who continue to have symptoms of ankle instability despite conservative therapy. Methods A total of eight patients who were 14 years or older with negative ankle MRI who continue to have symptoms of ankle instability despite conservative therapy were admitted to our institution from January 1, 2015 to December 31, 2021. Results Eight patients with a mean age of 36, and a mean body mass index (BMI) of 37.7. All patients presented with ankle pain, locking, and giving way in variable severity. All the patients had a radiograph followed by an ankle MRI, which showed normal alignment of ankle joints without abnormality. Initially, all patients were treated conservatively but did not show any improvement. After that, they underwent an operation of lateral ankle ligament reconstruction by modified Brostrom technique, followed by casting and physiotherapy. The symptoms of ankle instability resolved in all patients. The ankle pain resolved completely in six patients, improved in one patient, and did not improve in one patient. Conclusion Based on our results, we advocate reconstruction surgery by modified Brostrom technique for ligament repair in patients with clinical evidence of chronic ankle instability who have failed a trial of conservative management, even in the context of a normal ankle MRI.
Management of full-length complete ureteral avulsion
Authors: Kaifa Tang, Fa Sun, Yuan Tian, Yili Zhao
Journal: Int Braz J Urol (2016)
MeSH terms: Ureter / injuries, Ureteral Diseases / etiology, Ureteral Diseases / surgery, Ureteroscopy / adverse effects, Ureterostomy / methods, Case Reports, Adult, Anastomosis, Surgical, Disease Management, Humans, Hydronephrosis / surgery, Male, Omentum / surgery, Treatment Outcome, Urolithiasis / surgery

Introduction:
Complete ureteral avulsion is one of the most serious complications of ureteroscopy. The aim of this report was to look for a good solution to full-length complete ureteral avulsion.
Case presentation:
A 40-year-old man underwent ureteroscopic management. Full-length complete avulsion of ureter occurred during ureteroscopy. Pyeloureterostomy plus greater omentum investment outside the avulsed ureter and ureterovesical anastomosis were performed 6 hours after ureteral avulsion. The patient was followed-up during 34 months. Double-J tube was removed at 3 months after operation. Twenty three months after the first operation, the patient developed hydronephrosis because of a new ureter upside stone, then rigid ureteroscopy and holmium laser lithotripsy were used successfully.
Conclusion:
Pyeloureterostomy plus greater omentum investment outside the avulsed ureter and ureterovesical anastomosis may be a good choice for full-length complete ureteral avulsion.
Case report: 3D intracranial vessel wall MRI in Susac syndrome: potential relevance for diagnosis and therapeutic management
Authors: Antonio Lotti, Alessandro Barilaro, Alice Mariottini, Lorenzo Vannozzi, Marco Piergentili, Enrico Fainardi, Luca Massacesi
Journal: Front Neurol (2023)
Keywords: ce-flair, susac syndrome, vwi, leptomeningeal enhancement, neuroimaging, vasculitis, vessel wall imaging
MeSH terms: Case Reports

Background:
Susac syndrome (SS) is a rare immune-mediated vasculitis affecting retina, inner ear and brain. Assessment of central nervous system (CNS) involvement is currently based on standard brain magnetic resonance imaging (MRI) sequences. Accuracy of three dimensional (3D)-vessel wall imaging (VWI) was compared to standard sequences and contrast-enhanced-3D T2-fluid attenuated inversion recovery (CE-FLAIR) to assess CNS disease activity in two cases of definite SS.
Methods:
Brain MRI scan and retinal fluorescein angiogram (RFA) were performed at disease onset and at 1, 3, and 6 months after induction therapy start. CE-FLAIR and VWI based on 3D black-blood proton density weighted (PDW) with and without gadolinium were added to standard sequences on a 3 Tesla MRI scanner.
Results:
Contrast enhanced-VWI (CE-VWI) detected an abnormal diffuse leptomeningeal enhancement (LME) in both cases at onset and during follow-up. Pathological enhancement on CE-VWI persisted at 6-month brain MRI, despite absence of new lesions and disappearance of LME on CE-FLAIR. Follow-up RFA revealed new arterial wall hyperfluorescence in both cases.
Conclusions:
VWI may represent a useful tool for diagnosing and monitoring CNS disease activity in SS patients, as confirmed by concordance with RFA, leading treatment's choice and timing. Moreover, CE-VWI seemed at least as sensitive as CE-FLAIR in detecting LME, possibly being superior to the latter in posterior fossa. LME remission might be not accurate in predicting suppression of CNS inflammation in SS.
The surgical strategy of hormonally active primary cardiac paraganglioma sarcoma: A case report
Authors: Xiangyu Wang, Haiyuan Liu, Shuaipeng Zhang, Shaojun Huang, Chengxin Zhang
Journal: Front Cardiovasc Med (2022)
Keywords: cardiac paraganglioma, catecholamine, neuroendocrine tumor, primary cardiac oncology, surgical skill
MeSH terms: Case Reports

Cardiac paraganglioma is a kind of rare neuroendocrine tumor characterized by the persistent secretion of catecholamines. Under excessive exposure of catecholamines, some atypical symptoms are presented, including hypertension, arrhythmias, and headache. The case of surgical treatment of a 28-year-old woman with primary cardiac paraganglioma is presented for experience sharing and surgical skill improvements.
An Analysis of Pediatric Scar Progression Over Time
Authors: Blaire Slavin, Roberta Torres, Anne C Fischer
Journal: Eplasty (2018)
Keywords: infantile scar growth, multigenerational, pyloric stenosis, pyloromyotomy, right upper quadrant
MeSH terms: Case Reports

Objective: The advances in surgical approaches for a pyloromyotomy have all focused on creating smaller incisions from a right upper quadrant now to a laparoscopic umbilical incision. A key assumption is that the final scar retains the size of the original incision as the child matures. Our case reports on a family with several members, now adults, with the same surgery and same surgeon who had the right upper quadrant incision as infants to elucidate the extent of how infantile scars grow over time, significantly exceeding the original incision. Methods: We evaluated the various pyloromyotomy scars of our newborn patient, his maternal grandmother, and his two maternal twin aunts. One aunt (#1) was of normal stature, whereas her twin (#2) never went through a full vertical growth phase due to being stunted by Cornelia de Lange syndrome. For each member, we compared the length of the original incision with the current scar length to determine how much the scar has grown over time. Results: Significant scar growth was seen in the grandmother and aunt 1. In contrast aunt 2's scar did not grow significantly due to her stunted vertical growth from Cornelia de Lange syndrome. Conclusions: This case supports the notion that surgical incisions in infants grow more substantially than realized with age, resulting in larger scars than anticipated. Our findings suggest the reason why the laparoscopic pyloromyotomy has been popularized due to its incisions being so small that they continue to present a cosmetic advantage over time.
Relative hypocalcaemia and muscle cramps in patients receiving imatinib for gastrointestinal stromal tumour
Authors: Jamal M Zekri, Martin H Robinson, Penella J Woll
Journal: Sarcoma (2006)
MeSH terms: Case Reports

Purpose. Imatinib treatment causes muscle cramps in up to 40% of patients, but their pathogenesis is unknown. We present a case series illustrating an association between imatinib, relative hypocalcaemia, and the development of cramps. Patients. The index patient developed muscle spasms and cramps after receiving imatinib for gastrointestinal stromal tumour (GIST) for 5 months. The adjusted serum calcium had dropped to the lower limit of normal. The low serum calcium and muscle cramps improved on stopping imatinib and recurred on rechallenge. We reviewed the medical records of 16 further patients. Results. Two patients reported muscle cramps (12%). There was a rapid and sustained reduction in adjusted serum calcium in the first 6 months from 2.45 +/- 0.11 mmol/L (mean +/- SD) to 2.30 +/- 0.08 mmol/L (p = 0.025). Conclusion. Imatinib treatment of GIST is associated with reduction in serum calcium which may explain the development of neuromuscular symptoms. In patients receiving imatinib, serum electrolytes should be monitored and muscle cramps treated by correction of serum calcium, or an empirical trial of quinine sulphate.
Two Surgical Cases of Combined Hepatocellular-Cholangiocarcinoma, Intermediate-Cell Subtype: Potentially Characteristic Gross Features
Authors: Jiro Watanabe, Sohsuke Yamada, Yasuyuki Sasaguri, Masaru Inagaki, Hiromi Iwagaki
Journal: Case Rep Pathol (2018)
MeSH terms: Case Reports

We herein reported two rare surgical cases of primary combined hepatocellular-cholangiocellular carcinoma, intermediate-cell subtype (CHC-INT), showing potentially characteristic and specific gross findings on their cut surface: both CHC-INTs demonstrated poorly demarcated and expansive and/or infiltrative hepatic nodules in lobulated margins, appearing clearly whitish in color. We were finally able to accurately diagnose the current lesions after thorough analyses including an appropriate and wide panel of immunohistochemical antibodies. Despite that, all pathologists should be aware that the potentially characteristic gross features of primary CHC-INT might also be one of the powerful supplementary tools for reaching its correct, conclusive diagnosis.
Case Report: "ADHD Trainer": the mobile application that enhances cognitive skills in ADHD patients
Authors: Gonzalo Ruiz-Manrique, Kazuhiro Tajima-Pozo, Francisco Montañes-Rada
Journal: F1000Res (2014)
Keywords: adhd, mobile app, tct method, working memory

We report the case of a 10 year old patient diagnosed with attention deficit hyperactivity disorder (ADHD) and comorbid video game addiction, who was treated with medication combined with a novel cognitive training method based on video games called TCT method. A great risk of developing video game or internet addiction has been reported in children, especially in children with ADHD. Despite this risk, we hypothesize that the good use of these new technologies might be useful to develop new methods of cognitive training. The cognitive areas in which a greater improvement was observed through the use of video games were visuospatial working memory and fine motor skills. TCT method is a cognitive training method that enhances cognitive skills such as attention, working memory, processing speed, calculation ability, reasoning, and visuomotor coordination. The purpose of reviewing this case is to highlight that regular cognitive computerized training in ADHD patients may improve some of their cognitive symptoms and might be helpful for treating video game addiction.
Spontaneous Retroperitoneal Bleeding in a Patient with Primary Antiphospholipid Syndrome on Aspirin
Authors: Petros Ioannou, George Alexakis
Journal: Case Rep Emerg Med (2018)
MeSH terms: Case Reports

Retroperitoneal bleeding is a rare and difficult to diagnose condition, defined as bleeding in the retroperitoneal space without associated trauma or iatrogenic manipulation. It has been associated with hematologic diseases and malignancies and is more common in patients receiving systemic anticoagulation. A 50-year-old man on aspirin presented with abdominal pain. Physical examination revealed abdominal tenderness and a palpable mass at the left abdominal area. An abdominal CT revealed a spontaneous retroperitoneal hematoma due to bleeding of an intraparenchymal branch of the left renal artery. The patient underwent left nephrectomy in order to control the bleeding. Pathology of the kidney showed evidence of acute and chronic microangiopathy, renal artery stenosis, and renal vein thrombosis. Further work-up led to diagnosis of primary antiphospholipid syndrome. Treatment of spontaneous retroperitoneal bleeding varies from conservative in hemodynamically stable patients to invasive or even surgery in hemodynamically unstable patients. In our case, open surgery was performed due to the rapidly deteriorating patient's condition and the inability to embolize the bleeding vessel by interventional radiology. Physicians should always think of retroperitoneal bleeding in patients presenting with abdominal pain and signs of hypovolemia, especially if they have a bleeding disorder or receive anticoagulants or antiplatelets.
Case Report: A novel intergenic MIR4299/MIR8070-RET fusion with RET amplification and clinical response to pralsetinib in a lung adenocarcinoma patient
Authors: Sha-Sha Wang, Fang Wang, Zhen Zeng, Fang Gao, Huan-Huan Liu, Hui-Na Wang, Yi Hu, Hai-Feng Qin
Journal: Front Oncol (2022)
Keywords: ret intergenic fusion, lung adenocarcinoma, novel intergenic, pralsetinib, tyrosine kinase inhibitors
MeSH terms: Case Reports

The identification of receptor-tyrosine kinase gene (RET) fusions in lung cancer has become crucial owing to actionable events that predict responsiveness to tyrosine kinase inhibitors (TKIs). However, RET fusions with distinct partner genes respond differently to TKIs. In this case, a 60-year-old man was diagnosed with advanced lung adenocarcinoma. A novel RET-MIR4299/MIR8070 fusion and RET amplification were identified using next-generation sequencing (NGS). The patient was then administered with pralsetinib. After 3 weeks of therapy, the patient had a partial response. At the time of reporting, the patient was on continuous pralsetinib. These findings broaden the range of RET fusion types and provide the basis for the hypothesis that RET intergenic fusion and amplification respond to pralsetinib treatment in lung adenocarcinoma.
Case report: A 3-year follow-up study of simultaneous bilateral total hip arthroplasty for Femoral head necrosis in a patient with Kashin-Beck Disease
Authors: Xiangyu Chen, Haibin Liu, Houqing Wang, Liqiang Zheng, Jiayu Li, Lianqi Yan
Journal: Front Surg (2022)
Keywords: kashin-beck disease, femoral head necrosis, follow-up, simultaneous bilateral total hip arthroplasty, treatment
MeSH terms: Case Reports

Introduction:
Kashin-Beck Disease (KBD) is an endemic disease predominantly affecting joint and skeletal muscle, predisposing the articular cartilage to degeneration and necrosis. Currently,staged total hip arthroplasty is a common surgical method for advanced femoral head necrosis from KBD, but there are no reports in the literature on simultaneous bilateral total hip arthroplasty (SB-THA) for patients with KBD.
Case presentation:
A 42-year-old male from Shaanxi Province, an endemic area, had bilateral hip pain for 4 years, with hips inversion and a crossed gait. After preoperative preparation, a SB-THA was performed by a posterolateral approach. Postoperative medication and functional exercises were administered and the patient was followed up for at least 3 years after discharge. The patient's hip mobility, hip scores and quality of life scores were recorded in detail during the follow-up.
Result:
The patient stopped antibiotic treatment on the postoperative day-2, and all inflammatory indicators showed normal and started appropriate exercise, and the pain score decreased significantly. On the postoperative day-7, the patient had gradually adapted to various forms of rehabilitation exercises. He was discharged from the hospital on the postoperative day-10 and continued to be followed up. From the preoperative period to the last follow-up, the patient's bilateral hip mobility and functional scores improved significantly, and no adverse events such as hip pain, prosthesis loosening or dislocation were found at the last follow-up.
Conclusion:
The patient's performance was satisfactory both intraoperatively and in the early postoperative period, but the hip scores and quality of life scores began to plateau or even decline from the third year after surgery to the last follow-up, probably due to the influence of further damage to articular cartilage in other parts of the body.