OpenMed/multicare-articles huggingface dataset:
Can We Talk through a Robot As if Face-to-Face? Long-Term Fieldwork Using Teleoperated Robot for Seniors with Alzheimer's Disease
Authors: Kaiko Kuwamura, Shuichi Nishio, Shinichi Sato
Journal: Front Psychol (2016)
Keywords: alzheimer's disease, elderly care facility, elderly care robot, gerontology, teleoperated robot

This work presents a case study on fieldwork in a group home for the elderly with dementia using a teleoperated robot called Telenoid. We compared Telenoid-mediated and face-to-face conditions with three residents with Alzheimer's disease (AD). The result indicates that two of the three residents with moderate AD showed a positive reaction to Telenoid. Both became less nervous while communicating with Telenoid from the time they were first introduced to it. Moreover, they started to use more body gestures in the face-to-face condition and more physical interactions in the Telenoid-mediated condition. In this work, we present all the results and discuss the possibilities of using Telenoid as a tool to provide opportunities for seniors to communicate over the long term.
Case report: Evolution of pulmonary manifestations and virological markers in critical COVID-19 infection in Bruton's agammaglobulinemia
Authors: Nina Rise, Toke Touborg, Ditte Helene Lundsted, Michael Dalager-Pedersen, Trine H Mogensen
Journal: Front Immunol (2022)
Keywords: bruton’s agammaglobulinemia, covid-19, sars-cov-2, inborn error of immunity, vaccination, viral evolution
MeSH terms: Agammaglobulinemia / complications, Agammaglobulinemia / diagnosis, COVID-19, Genetic Diseases, X-Linked / complications, Genetic Diseases, X-Linked / diagnosis, Case Reports, Adult, Disease Progression, Humans, Male, SARS-CoV-2, Bruton type agammaglobulinemia

Despite several reports and small case series on the disease course of SARS-CoV-2 infection in patients with inborn errors of immunity (IEI), including X-linked agammaglobulinemia (XLA), this topic remains incompletely described. Here we present the case of a 38-year-old unvaccinated man with XLA, who acquired SARS-CoV-2 infection and experienced a protracted disease course with 47 days of SARS-CoV-2 positivity, critical COVID-19 with respiratory insufficiency necessitating intensive care and ventilatory support, and prompting repeated intensified treatments with remdesivir, dexamethasone, and monoclonal antibodies to eventually control infection. We describe the disease course and treatment and review the current literature on COVID-19 susceptibility and evidence for vaccine efficacy in patients with XLA.
Ibrutinib Treatment of Mantle Cell Lymphoma Relapsing at Central Nervous System: A Case Report and Literature Review
Authors: Donato Mannina, Barbara Loteta
Journal: Case Rep Hematol (2017)
MeSH terms: Case Reports

Mantle cell lymphoma (MCL) accounts for about 5% of all lymphomas. Its clinical and histological features are heterogeneous. After a frequently good initial response, the disease generally and repeatedly relapses and finally the outcome is poor. Particularly severe is the prognosis of the rare occurrence of CNSi (Central Nervous System involvement). Ibrutinib, an oral inhibitor of Bruton tyrosine kinase (BTK), has shown strong activity in relapsing patients with Chronic Lymphocytic Leukemia (CLL) and MCL. Few reports are available about treatment with ibrutinib of patients presenting CNSi by lymphoproliferative diseases (LPD). In all of them, ibrutinib, at the dosage between 420 and 560 mg/day, showed an impressive effectiveness. Here we describe a case of MCL with CNS relapse showing an excellent response to ibrutinib administered at the unusual dose of 280 mg/day because of concomitant treatment of cardiological disease.
Pachychoroid Spectrum Disorder Findings in Patients with Coronavirus Disease 2019
Authors: Mojtaba Abrishami, Ramin Daneshvar, Nasser Shoeibi, Neda Saeedian, Hamid Reza Heidarzadeh, Seyedeh Maryam Hosseini
Journal: Case Rep Ophthalmol Med (2021)
MeSH terms: Case Reports

Purpose:
To report the occurrence of acute, bilateral, central serous chorioretinopathy (CSC), and pachychoroid spectrum disorder findings in patients with coronavirus disease 2019 (COVID-19).
Methods:
In recovered cases of COVID-19 with visual disturbances, complete ocular examinations with multimodal retinal and choroidal evaluation, including enhanced depth imaging optical coherence tomography, fluorescein or indocyanine green angiography, and blue autofluorescence, were obtained.
Results:
Four COVID-19 recovered patients presented with bilateral blurred vision. Ocular examination and imaging revealed pachychoroid and pachyvessels associated with choroidal hyperpermeability without any obvious intraocular inflammation. Bilateral localized serous retinal detachment was obvious in three cases compatible with pachychoroid associated with CSC manifestation and pachychoroid pigment epitheliopathy in one patient. CSC was resolved with treatment by steroidal antimineralocorticoid (Eplerenone) in two patients and by photodynamic therapy in one patient. None of the patients reported emotional stress and history of corticosteroid consumption.
Conclusion:
Hyperpermeability of the choroid, pachychoroidopathy, or choroidal vessel congestion can be observed or exacerbated in association with COVID-19.
Bedside echocardiography for undifferentiated hypotension: diagnosis of a right heart thrombus
Authors: James F Kenny, Xun Zhong, Cara Brown, Devjani Das, Brock Royall, Monica Kapoor
Journal: West J Emerg Med (2015)
MeSH terms: Heart Diseases / diagnostic imaging, Hypotension / etiology, Thrombosis / diagnostic imaging, Case Reports, Aged, 80 and over, Female, Heart Diseases / complications, Humans, Point-of-Care Systems, Thrombosis / complications, Ultrasonography

A free-floating right heart thrombus is often a harbinger of a massive pulmonary embolism and must be diagnosed and treated rapidly in order to avoid significant adverse sequelae. We present the case of an 84-year-old female who presented with two days of dyspnea and was hypotensive on arrival. Bedside ultrasound was performed by the emergency physician and showed a large, mobile right heart thrombus leading to immediate administration of a thrombolytic. In this case, bedside ultrasound was utilized to help further delineate clinical care in a progressively worsening patient, leading to a potentially lifesaving treatment.
Clinical Features and Outcomes of Dipeptidyl Peptidase-4 Inhibitor-Associated Bullous Pemphigoid (DPP4i-Associated BP) in Thai Patients
Authors: Yotsapon Thewjitcharoen, Ekgaluck Wanothayaroj, Chattip Thammawiwat, Sriurai Porramatikul, Chuleekorn Vorayingyong, Soontaree Nakasatien, Sirinate Krittiyawong, Kumutnart Chanprapaph, Thep Himathongkam
Journal: Case Rep Endocrinol (2020)
MeSH terms: Case Reports

The use of dipeptidyl peptidase-4 inhibitors (DPP4i) appears to be associated with a small but significantly elevated risk of bullous pemphigoid (BP). Although the pathogenic mechanism of DPP4i-associated BP remains unclear, this adverse event is reported with multiple gliptins, suggesting a class effect. However, previous studies from various countries showed that vildagliptin had been implicated in most cases. The aim of this study was to illustrate a case series of DPP4i-associated BP in Thai patients. We conducted a retrospective study from consecutive cases of BP in people with type 2 diabetes mellitus (T2DM) from January 2008, the year in which the first DPP4i was introduced in Thailand, until December 2019. During the study period, 10 BP patients with T2DM were identified. A total of 5 DPP4i-associated BP (3 on vildagliptin, 1 on linagliptin, and 1 on sitagliptin) were found. All patients were male with a mean age at BP development of 80.4 years (73-86 years). All patients had a long-standing duration of diabetes (median duration 34 years), and mean A1C was 7.5 ± 1.4%. The median time to BP development after the introduction of DPP4i was 64 months (range 20-128 months). The severity of BP was classified as mild in 2 cases. In all cases, the association between the drug intake and BP onset was classified as "possible" according to the Naranjo causality scale. All of the patients continued taking DPP4i after BP diagnosis, and one patient died of lung cancer 18 months after BP diagnosis. Only 2 patients could achieve complete remission at least 2 months after stopping DPP4i. Our case series demonstrated a potential link between DPP4i and the development of BP, which mainly occurred in very elderly male patients. The latency period from an introduction of DPP-4i could be several years, and the clinical course after DPP4i discontinuation varied. Clinicians prescribing DPP4i should be aware of this association and consider stopping this medication before a refractory disease course ensues.
A Rare Cause of Abdominal Pain in Childhood: Cardiac Angiosarcoma
Authors: Elvan Caglar Citak, Murat Ozeren, M Kerem Karaca, Derya Karpuz, Feryal Karahan, Eda Bengi Yilmaz, Yuksel Balci, Pelin Ozcan Kara, Rabia Bozdogan Arpaci
Journal: Braz J Cardiovasc Surg (2018)
MeSH terms: Abdominal Pain / etiology, Heart Neoplasms / complications, Hemangiosarcoma / complications, Case Reports, Abdominal Pain / diagnostic imaging, Adolescent, Female, Heart Neoplasms / diagnostic imaging, Heart Neoplasms / surgery, Hemangiosarcoma / diagnostic imaging, Hemangiosarcoma / surgery, Humans, Rare Diseases, Tomography, X-Ray Computed

Cardiac angiosarcomas are extremely rare in childhood, they are rapidly progressive tumours that often present themselves as diagnostic dilemmas, resulting in delayed diagnosis. Also, extracardiac manifestations, including abdominal pain, are extremely rare in patients with intracardiac tumors. We herein present the case of a 15-year-old girl who presented with abdominal pain. Echocardiography and thoracic computed tomography showed right atrial mass. The patient underwent surgery, chemotherapy, and radiotherapy. Eight months after treatment, abdominal recurrence was detected. The abdominal mass was resected, and radiotherapy and new chemotherapy protocol were given. The present case illustrates a rare case of primary cardiac angiosarcoma posing a diagnostic dilemma in an adolescent girl.
Targeted Nutritional and Behavioral Feeding Intervention for a Child with Autism Spectrum Disorder
Authors: Kelly Barnhill, Amanda Tami, Claire Schutte, Laura Hewitson, Melissa L Olive
Journal: Case Rep Psychiatry (2016)

A variety of feeding issues and concerns, including food aversion, food selectivity, and complete food refusal, are not uncommon among children with autism spectrum disorder (ASD). Other underlying issues are often comorbid with the concerns for feeding and ASD. These may include food allergies, gastrointestinal issues, oral motor issues, and swallowing disorders. The refusal to consume particular foods coupled with the inability to tolerate, digest, and absorb these foods can compromise an individual's overall nutrition status. Therefore, a child's behavior toward food and feeding activities has great impact on dietary intake, nutritional status, and growth. This case report is the first to document combined medical, behavioral, and nutritional intervention for a toddler with ASD and comorbid feeding disorder.
Malignant Degeneration of a Mature Ovarian Teratoma
Authors: Mariam Mahtate, Sarah Talib, Aziz Slaoui, Najia Zeraidi, Amina Lakhdar, Brahim Rhrab, Aziz Baydada
Journal: Case Rep Obstet Gynecol (2021)
MeSH terms: Case Reports

Mature cystic teratoma is the most common type of ovarian germ cell neoplasm, but occasionally, it can undergo malignant transformations, especially in postmenopausal women. These secondary malignant neoplasms are most commonly squamous cell carcinomas. The absence of clinical and radiological specificity of this transformation means that the diagnosis remains purely histological. Data is insufficient regarding the appropriate management given their rarity. However, the treatment is multidisciplinary and is based on surgery and a platinum-based chemotherapy regimen. We report the case of a 53-year-old postmenopausal female patient with malignant transformation of the ovarian teratoma who was treated surgically and whose outcome was favorable. The diagnosis of the teratoma was evoked on imaging, while the diagnosis of squamous cell carcinoma was revealed on histology. Malignant transformation is an uncommon complication of mature ovarian teratomas. No clinical, radiological, or biological sign is specific; therefore, resection of any ovarian mass, even asymptomatic, is required.
Cardiac Arrest and Successful Extracorporeal Cardiopulmonary Resuscitation as a Result of a Refeeding Syndrome in a Young Female with Anorexia Nervosa
Authors: Daniela Waddell, Felix Meincke, Samer Hakmi, Hendrick van der Schalk, Niklas Schenker, Jonas Hahn, Anna Moschner, Mintje Bohné, Da-Un Chung, Stephan Willems, Dietmar Kivelitz, Edda Bahlmann
Journal: Case Rep Cardiol (2020)
MeSH terms: Case Reports

Anorexia nervosa is a potentially life-threatening eating disorder, characterized by an abnormally low body weight. This case report illustrates a 22-year old female with cardiac arrest due to a refeeding syndrome in a patient with anorexia nervosa. It features the successful use of extracorporeal cardiopulmonary resuscitation in a case of severe left ventricular dysfunction resulting in a favorable outcome. Conclusion. We present the first case of a cardiac arrest due to a refeeding syndrome in anorexia nervosa featuring the successful use of an extracorporeal cardiopulmonary resuscitation approach as a bridge to full recovery.
A Rare Case of Gastrointestinal Stromal Tumor with a Liver Metastasis Infiltrating the Inferior Vena Cava and Extending to the Right Atrium with an Early Recurrence after Surgical Extraction
Authors: Dimitrios Siamkouris, Marc Schloesser, Amr Yousef, Elmar Offers
Journal: Case Rep Cardiol (2019)
MeSH terms: Case Reports

Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract. The major cause of GIST is the presence of an abnormal form of tyrosine protein kinase (KIT) protein also known as CD117, which causes uncontrollable growth of the gastrointestinal cells. Most studies report incidences between 10 and 15 cases of GISTs per million. Metastases to the liver and peritoneum are the most frequent. We report a case of advanced GIST with a liver metastasis infiltrating the inferior vena cava (IVC) and extending to the right atrium in the form of a large, floating, isolated intracardiac liver metastasis with diastolic prolapsing through the tricuspid valve. This is a very rare manifestation. One week after heart surgery and removal of a 5 × 6 cm tumor mass from the right atrium and the IVC, echocardiography depicted an early recurrence.
An Unusual Case of Candida albicans Empyema in Patient With Gastric Cancer and Colon Metastasis
Authors: Bhavi Trivedi, Ilma Vahora, Jesus Guzman, Rohan Desai, Juan Cartagena, Aymara Y Chang
Journal: Cureus (2023)
Keywords: candida albicans empyema, candida empyema, fluconazole, immunocompromised hosts, pleural effusion
MeSH terms: Case Reports

Candida empyema is a rare presentation seen in immunocompromised patients, with a high mortality rate if not treated appropriately. We present a rare case of Candida albicans empyema in a patient with gastric cancer undergoing chemotherapy who recently underwent cholecystectomy, successfully treated with fluconazole and drainage. This case not only highlights an unusual presentation of a common pathogen but stresses the fact that when patients with malignancy, present with pleural effusion, candida should be in the differential. Early detection is key in such cases, as outcomes are poor if diagnosis and treatment are delayed.
Isolated renal hydatid disease: laparoscopic approach to an uncommon entity (case report)
Authors: Saket Kumar, Saurabh Singla, Ausaf Ahmad, Nishant Kurian, Venkat Rao Chidipotu
Journal: Pan Afr Med J (2021)
Keywords: renal hydatid cyst, case report, echinococcal cyst, isolated, laparoscopic
MeSH terms: Echinococcosis / diagnosis, Kidney Diseases / diagnosis, Laparoscopy, Case Reports, Adult, Echinococcosis / surgery, Humans, Kidney Diseases / parasitology, Kidney Diseases / surgery, Male

Hydatidosis is a parasitic disease, endemic in various parts of the World. It frequently involves liver and lungs and, rarely, other organs as well. Isolated renal hydatidosis is a rare entity that accounts for less than 3% of all hydatid cases. Surgery remains the mainstay of treatment. We hereby report a case of isolated renal hydatid cyst involving left kidney that was managed by laparoscopic approach.
Intrahepatic pseudoaneurysm following penetrating abdominal injury: Surgical and endovascular management of 2 complicated cases
Authors: Laila H AbuAleid, Khaled Elshaar, Almoaiad A Alhazmi, Mohammed Al Sherbini, Khalid Albohiri
Journal: Int J Surg Case Rep (2020)
Keywords: embolization, endovascular, hepatic artery, intrahepatic, pseudoaneurysm, trauma
MeSH terms: Case Reports

Introduction:
Post-traumatic pseudoaneurysm of the hepatic artery is a rare complication of abdominal injury. Prompt intervention is essential to avoid a life-threatening hemorrhage. We report two complicated cases of intrahepatic pseudoaneurysm (IHPA).
Presentation of cases:
Case 1: A victim of a bomb blast with thoracoabdominal injury presented in hypovolemic shock. Emergency laparotomy revealed actively bleeding liver lacerations, which had been successfully controlled with perihepatic packing. After 72 h, computed tomography (CT) of the abdomen showed a 3 cm × 1.8 cm IHPA of the left hepatic artery, which was treated with endovascular microcoils embolization. Postoperatively, the patient developed bile leakage and biliopleural fistula, which were managed conservatively. Case 2: A patient suffered a shotgun injury to the abdomen. In laparotomy, a grade III liver laceration was noted. The bleeding was controlled with perihepatic packing. The packs were removed 48 h later. Ten days postoperatively, the patient developed severe abdominal pain with shock, CT of the abdomen showed; 24 cm × 13 cm × 8 cm subcapsular liver hematoma. Superselective hepatic angiography showed a 1-cm IHPA of the right hepatic artery. The entry and exit points of the aneurysm were successfully embolized with two microcoils. No complications related to angioembolizaion were encountered.
Discussion:
IHPA following bomb blast and shotgun injury is rarely reported. Timely diagnosis is crucial.
Conclusion:
We advise to keep in mind the possibility of IHPA, when dealing with high-grade liver injury. CT is recommended before removal of perihepatic packs, as it may pick up a life-threatening pseudoaneurysm.
Case Report: An incidentaloma that catches your eye - adrenal myelolipoma
Authors: Rosanna D'Addosio, Joselyn Rojas, Valmore Bermúdez, Flor Ledesma, Kyle Hoedebecke
Journal: F1000Res (2017)
Keywords: myelolipoma adrenal, adrenal incidentaloma, benign adrenal tumor

Background: Adrenal incidentaloma refers to the incidental finding of a tumor in the adrenal gland, where nonfunctional forms are the most common variant. Myelolipoma is a rare (0.08-0.4%) occurrence characterized by adipose and hematopoietic tissue. The aim of this case report is to describe the diagnosis and appropriate management of a myelolipoma in an asymptomatic patient, which was originally considered an incidental hepatic hemangioma prior to being identified as a giant adrenal adenoma. Case description: The patient was a 54 year old obese female with a recent diagnosis of diabetes type II and dyslipidemia with recent ultrasound imaging suggestive of a hepatic hemangioma. An MRI was performed revealing a 7x6cm lesion in the right adrenal area indicating a giant adrenal adenoma. An adrenalectomy was performed without complications. The pathology report identified a myelolipoma. Discussion: The incidence of myelolipoma has recently increased due to advances in radiological techniques. Its etiology is unclear and the most accepted theories support a myeloid cell metaplasia in the embryonic stage as a result of stress, infections, or adrenocorticotropic hormone or erythropoietin stimulus. Contributing components may include bone morphogenetic protein 2 and β-catenin, as well as the presence of the chromosomal translocation (3, 21) (q25; p11). Despite its benign nature, the association with other adrenal lipomas must be ruled out. A biochemical evaluation is essential for detecting subclinical states, such as Cushing syndrome and pheochromocytoma. Conclusion: Adrenal myelolipomas are rare benign tumors that are generally asymptomatic. Uncertainty still exists surrounding their etiology. Surgical management depends on hormone production, tumor size, high risk features on imaging and patient consent. Additional information is needed to better understand myelolipomas, their etiology, and clinical management. Incidentalomas may confuse the physician and patient. Ensuring proper multidisciplinary management based on the clinical guidelines of endocrinology allowed a satisfactory resolution of this case.
Fibromyxoid Nephrogenic Adenoma in the Ureter
Authors: Benjamin M Dropkin, Giovanna A Giannico, Peter A Reisz, David F Penson, Ryan S Hsi
Journal: J Endourol Case Rep (2018)
Keywords: fibromyxoid, nephrogenic adenoma, ureter, ureteral neoplasm
MeSH terms: Case Reports

Background: Nephrogenic adenoma is a benign lesion found in the genitourinary tract, often at sites of prior inflammation, and is characterized by tubular, papillary, or tubulopapillary structures. It is thought to arise from distal migration and implantation of renal tubular cells into the renal pelvis, ureter, bladder, or urethra. These tumors often resemble malignant neoplasms. Morphologic variants include small tubules, signet ring-like pattern, papillary formations, flat pattern, and vessel-like structures. A fibromyxoid variant was first described in 2007. Here, we present the first known cases of fibromyxoid nephrogenic adenoma of the ureter. Case Presentations: A 79-year-old white man presented with asymptomatic right hydroureteronephrosis to the level of the mid-ureter with associated right ureteral wall thickening found on surveillance CT scan for lymphoma. A 59-year-old white man presented with a right ureteral stricture after ureteroscopic ureteral injury and underwent effective robotic ureteroureterostomy. Pathology analysis in both cases revealed fibromyxoid nephrogenic adenoma. Conclusion: Fibromyxoid nephrogenic adenoma may occur in the ureter. Knowledge of this rare tumor is important for urologists and pathologists to prevent misdiagnosis and overtreatment of a typically benign process.
Reflectance confocal microscopy as an aid to dermoscopy to improve diagnosis on equivocal lesions: evaluation of three bluish nodules
Authors: Sara Bassoli, Stefania Seidenari, Giovanni Pellacani, Caterina Longo, Anna Maria Cesinaro
Journal: Dermatol Res Pract (2010)
MeSH terms: Case Reports

Nodular lesions can be difficult to diagnose under dermoscopy alone, since they often lack specific diagnostic features. Confocal microscopy can be used as an aid to dermoscopy, to increase the diagnostic accuracy on equivocal skin lesions. We report three cases of bluish nodular lesions, difficult to diagnose under dermoscopy alone. Confocal features were very useful in these cases to lead us to the correct diagnosis, recognizing benign versus malignant entities. Histopathology is also reported, with high correspondence compared to the confocal imaging.