OpenMed/multicare-articles huggingface dataset:
Congenital Temporomandibular Joint Ankylosis: Case Report and Literature Review
Authors: Ryan Chin Taw Cheong, Karim Kassam, Simon Eccles, Robert Hensher
Journal: Case Rep Otolaryngol (2016)

Congenital temporomandibular joint (TMJ) ankylosis is an uncommon condition that presents itself at or soon after birth in the absence of acquired factors that could have contributed to the ankylosis such as infection and trauma. The experience of managing one such case is reported in light of a review of the literature on this condition. Key management principles include adequate removal of the ankylotic mass, costochondral grafting, and post-op physiotherapy. Most patients reported in the literature with the condition experienced relapse. This echoes our own experience where there was recurrence of the ankylosis. However, after removal of the ankylotic mass, the patient maintains a satisfactory maximal incisal opening (MIO) till the present day. The additional challenges faced in the congenital form in addition to the already complex management of acquired paediatric temporomandibular joint ankylosis are (1) much earlier insult to the TMJ, (2) reduced opportunity for neuromuscular development of the muscles of mastication, and (3) reduced compliance with postoperative physiotherapy programmes due to the younger age of these patients.
Is routine screening for silent pulmonary embolism justified in patients with deep vein thrombosis?
Authors: Marcela Juliano Silva, Cynthia de Almeida Mendes, Sergio Kuzniec, Mariana Krutman, Nelson Wolosker
Journal: J Vasc Bras (2021)
Keywords: anticoagulants, embolism and thrombosis, pulmonary embolism, vena cava filters, venous thrombosis

The incidence of asymptomatic pulmonary embolism (PE) exceeds 70% in patients with deep venous thrombosis (DVT), even in cases of distal deep vein thrombosis. We report the case of a patient with a diagnosis of DVT in the lower left limb associated with asymptomatic PE who presented late symptoms due to this same PE. The absence of acute symptoms and the late onset of symptoms could have provoked doubts about the most appropriate treatment, resulting in unnecessary interventions, if pulmonary embolism had not already been diagnosed with tomography. In the present case, we demonstrate that computed tomography angiography conducted at the time of DVT diagnosis accurately diagnosed PE and prevented any misinterpretation of recurrent DVT in a patient already being medicated, which could have been mistakenly interpreted as demonstrating failure of anticoagulant therapy. Such a situation could lead to unnecessary intervention to fit an inferior vena cava filter. We cannot suggest that a classic medical conduct should be reformulated simply on the basis of a case report. However, we would be remiss not to suggest that well-designed studies should be carried out in the future to assess the need for this examination in the acute phase.
A Case Report of Multiple Gastrointestinal Stromal Tumors: Imaging Findings, Surgical Approach, and Review of the Literature
Authors: Mariarita Tarallo, Cristina Carruezzo, Filippo Maria Dentice Di Accadia, Antonella Del Gaudio, Damiano Caruso, Michela Polici, Daniele Crocetti, Umberto Costi, Andrea Polistena, Francesco Panzuto, Andrea Laghi, Giuseppe Cavallaro, Enrico Fiori
Journal: Front Surg (2022)
Keywords: computed tomography, gastrointestinal stromal tumor, minimally invasive surgery, multiple gastrointestinal stromal tumors, surgical resection
MeSH terms: Case Reports

Introduction:
Multiple gastrointestinal stromal tumors (GISTs) are rare tumors. Differential diagnosis between metastatic and multiple GISTs represents a challenge for a proper workup, prediction prognosis, and therapeutic strategy.
Case presentation:
We present the case of 67-year-old man with computed tomography (CT) evidence of multiple exophytic lesions in the abdomen, reaching diameters ranging from 1 to 9 cm, without any signs of organs infiltration, and resulting positive at 18F-FDG-PET/CT. Laparoscopic biopsy revealed multiple GISTs, and surgical resection by using an open approach was performed to achieve radicality. Moreover, an extensive review of the current literature was performed.
Results:
Small GISTs (<5 cm) can be treated by the laparoscopic approach, while in the case of large GISTs (>5 cm), tumor location and size should be taken into account to reach the stage of radical surgery avoiding tumor rupture. For metastatic GISTs, Imatinib represents the first choice of treatment, and surgery should be considered only in a few selected cases when all lesions are resectable.
Conclusion:
Sporadic multiple GISTs are a rare event, imaging findings are not specific for GISTs, and biopsy requires a secure diagnosis and proper management. In the case of large lesions, with a high risk of vessels injury, laparotomy excision should be considered to achieve radicality and to avoid tumor rupture.
Case Report: A Rare Case of Right-Sided Papillary Fibroelastoma in a 1-Year-Old With Congenital Heart Disease
Authors: Ali Ahmad, Edward A El-Am, Reto D Kurmann, Donald J Hagler, Melanie C Bois, Joseph J Maleszewski, Kyle W Klarich
Journal: Front Cardiovasc Med (2021)
Keywords: cardiac tumor, case report, congenital heart disease, papillary fibroelastoma, pediatrics
MeSH terms: Case Reports

Introduction: Cardiac papillary fibroelastomas (PFEs) are the most common primary benign cardiac tumors, although they are somewhat unusual in children and typically seen on the left-sided cardiac valves. Case summary: A 10-week-old patient was found to have a partial atrioventricular canal defect, with associated tricuspid and mitral regurgitation. He was medically managed until 1 year of age, when surgical correction was done. During the procedure, a PFE was found incidentally on the TV. Conclusion: This is one of the youngest patients to be reported with PFE, thus adding to the literature of these unusual cases in children.
Interactive Learning Environments for the Educational Improvement of Students With Disabilities in Special Schools
Authors: Rocío García-Carrión, Silvia Molina Roldán, Esther Roca Campos
Journal: Front Psychol (2018)
Keywords: disabilities, inclusion, interaction, learning, special schools

Providing an inclusive and quality education for all contributes toward the Sustainable Development Goals of the United Nations. High-quality learning environments based on what works in education benefit all students and can be particularly beneficial for children with disabilities. This article contributes to advance knowledge to enhance the quality of education of students with disabilities that are educated in special schools. This research analyses in which ways, if any, interactive learning environments can be developed in special schools and create better learning opportunities for children with disabilities. A case study was conducted with students with disabilities (N = 36) and teaching staff in a special school, involving interviews and focus groups. We argue that rethinking the learning context by introducing instruction models based on interaction benefit children with disabilities and provide high-quality learning and safe and supportive relationships for these students, thereby promoting their educational and social inclusion.
The advantages of demographic change after the wave: fewer and older, but healthier, greener, and more productive?
Authors: Fanny Kluge, Emilio Zagheni, Elke Loichinger, Tobias Vogt
Journal: PLoS One (2014)
MeSH terms: Efficiency, Population Dynamics, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Germany, Humans, Life Expectancy

Population aging is an inevitable global demographic process. Most of the literature on the consequences of demographic change focuses on the economic and societal challenges that we will face as people live longer and have fewer children. In this paper, we (a) briefly describe key trends and projections of the magnitude and speed of population aging; (b) discuss the economic, social, and environmental consequences of population aging; and (c) investigate some of the opportunities that aging societies create. We use Germany as a case study. However, the general insights that we obtain can be generalized to other developed countries. We argue that there may be positive unintended side effects of population aging that can be leveraged to address pressing environmental problems and issues of gender inequality and intergenerational ties.
Osteochondral Fracture Lateral Femoral Condyle Treated with ORIF Using Z-Plasty: A Modification of Coonse and Adams Approach
Authors: Sanjay Agarwala, Ganesh S Mohrir, Brijbhushan S Mahajan
Journal: Case Rep Orthop (2011)
MeSH terms: Case Reports

Osteochondral fractures of lateral femoral condyle are common in adolescents and young adults. They are usually caused by direct trauma or twisting injuries of the knee. We present a case of large osteochondral fracture of lateral femoral condyle involving the articular surface in a fifteen-year-old male with a positive history of significant weight gain of 5 kilograms in last six months. Blood investigations reported low vitamin D and testosterone levels with elevated alkaline phosphatase. Adequate exposure was achieved by doing Z-plasty of quadriceps apparatus. The fracture was treated with open reduction and internal fixation using Herbert's screws. Medical management in the form of vitamin D and calcium along with testosterone was given. After the surgery, full weight-bearing was allowed at three months. At one year followup, patient has good quadriceps function without any weakness of the muscle.
Adrenal incidentalomas in cancer patients are not always "innocent": a case report and review of the literature
Authors: Panagiota Economopoulou, Giannis Mountzios, Ioannis Kotsantis, Marios Bakogeorgos, Vassilios Ramfidis, Ioannis Kapiris, Efstratios Patsouris, Nikolaos Kentepozidis
Journal: Case Rep Med (2013)

Herein, we report an unusual case of a 78-year-old woman with synchronous presentation of sigmoid cancer and a nonfunctioning primary adrenal cortex carcinoma, who developed superior vena cava syndrome due to metastatic lymphadenopathy from the latter malignancy. Our case suggests that adrenal incidentalomas during initial staging evaluation after cancer diagnosis are not always "innocent" and should not be "a priori" considered incidental findings attributed to hyperplasia, adenoma or even a non life-threatening metastasis from the primary tumor. It also emphasizes the importance of a continuous assessment of patients with synchronous primary malignancies, in order to timely evaluate changes in clinical or biological behavior and administrate the appropriate treatment.
Primary Cutaneous T-Cell Lymphoblastic Lymphoma: Case Report and Literature Review
Authors: Sharad Khurana, Manuel Beltran, Liuyan Jiang, Ernesto Ayala, Vivek Roy
Journal: Case Rep Hematol (2019)
MeSH terms: Case Reports

Cutaneous involvement by precursor T-cell lymphoblastic leukemia/lymphoma (T-ALL/LBL) is rare, and almost all cases are seen in association with bone marrow, blood, and/or lymph node involvement. Presentation with isolated skin involvement is very rare. Literature review revealed only one case report of primary cutaneous T-cell LBL. We discuss here another patient diagnosed with primary cutaneous T-cell LBL at our institute. This patient was initially misdiagnosed as having peripheral T-cell lymphoma NOS. Cytogenetic analysis showed the CDKN2A deletion (-9p21×2) in addition to three intact copies of ABL1 (+9q34). Although she failed multiple lines of intensive chemotherapy, her disease remained confined to the skin. We believe that this presentation of T-LBL is underreported, and many patients are likely misdiagnosed as having high-grade cutaneous T-cell lymphomas. With this case and literature review, we would like to highlight the importance of keeping lymphoblastic lymphoma on the differential diagnosis of cutaneous T-cell lymphoma-like lesions to avoid delay in diagnosis and inappropriate treatment of this aggressive disease.
Case report: 38-year-old female patient with severe legionellosis but no source of infection
Authors: Benedikt M J Lampl, Werner Strigl, Dieter Winner, Michael T Pawlik
Journal: GMS Hyg Infect Control (2019)
Keywords: ecmo, exposure, infection prevention, legionellosis, risk factors
MeSH terms: Case Reports

We report about a 38-year-old female patient with an extremely severe case of legionellosis. The patient had to be treated in the intensive care unit for more than a month. Extracorporeal membrane oxygenation (ECMO) had to be established in order to save the patient's life. The patient did not belong to any risk group (i.e., age >50, smoker, immunosuppression, chronic disease, male sex). Infection control investigations carried out by the Public Health Department could not reveal concrete exposures likely to cause the infection. The serotypes in the patient material (Legionella pneumophila serotype 2-14) and in the samples taken from the showerhead in the patient's apartment (Legionella pneumophila serotype 1) were not identical. Results of the examination performed according to the German Drinking Water Ordinance (Trinkwasserverordnung, TrinkwV) carried out in 2017 in the patient's apartment, showed that the technical measures limit (Technischer Maßnahmenwert, TMW) was not exceeded. The patient has survived through the extensive use and efforts of intensive care measures. In general, a concrete exposure to Legionella is often not ascertainable, as in the case presented. This raises the question of how and whether such cases of legionellosis are preventable.
Rothia mucilaginosa Meningitis in a Child with Myelodysplastic Syndromes
Authors: Fumihiro Ochi, Ryota Nakamura, Reiji Miyawaki, Kyoko Moritani, Shinobu Murakami, Hisamichi Tauchi
Journal: Case Rep Pediatr (2021)
MeSH terms: Case Reports

Rothia mucilaginosa is a Gram-positive coccus and an opportunistic pathogen in immunocompromised hosts. The microorganism has been implicated in serious infections, including bacteremia meningitis or endocarditis. However, there is a dearth of investigations on meningitis, especially in children. As this infection is rare and only a few cases have been recorded, evidence-based guidelines for adequate infection treatment are lacking. We herein report the case of a 12-year-old boy with myelodysplastic syndromes (MDS) presenting with a change in mental status who was diagnosed as having febrile neutropenia and bacterial meningitis caused by R. mucilaginosa at 23 days after unrelated cord blood transplant. In our case, the minimum inhibitory concentrations (MICs) of meropenem and vancomycin (VCM) were both ≤1 μg/mL, whereas the MIC of daptomycin (DAP) was 4 μg/mL. The patient was treated with intravenous antimicrobial therapy due to meropenem for 43 days because he had febrile neutropenia. During follow-up, the patient had no neurological complications. We retrospectively reviewed the antimicrobial susceptibility of all R. mucilaginosa isolates (n = 5) from blood or cerebrospinal fluid cultures at our hospital. The MIC of VCM was <0.5 μg/mL for all strains, whereas the MIC of DAP was ≥2 μg/mL for all strains. The MIC of MEPM was >1 μg/mL for one strain. We recommend choosing VCM as the primary treatment for invasive R. mucilaginosa infections until antimicrobial susceptibility results are known, especially in immunocompromised children.
Case report: Prenatal diagnosis of rare chromosome mosaicism: discordant results between chorionic villi and amniotic fluid samples
Authors: Lingping Li, Xijing Liu, Qinqin Li, Lili Zhang, Yueyue Xiong, Shanling Liu, He Wang, Hongmei Zhu, Xuemei Zhang
Journal: Front Genet (2023)
Keywords: chromosome mosaicism, genetic testing, monosomy x, nuchal cystic hygroma, prenatal diagnosis
MeSH terms: Case Reports

Objective: We described a unique case of near-negative chromosome mosaicism in chorionic villi but complete monosomy X in amniotic fluid. Methods: Chorionic villus sampling and amniocentesis were performed separately in the first and second trimesters. Chromosomal microarray (CMA) and rapid aneuploidy detection (QF-PCR and FISH) were performed on placental villi and uncultured amniotic fluid. After pregnancy termination, the placenta, umbilical cord, and fetal muscle tissues were sampled for FISH detection. Results: The CMA revealed a lower signal from chromosome X in chorionic villi, with a copy number of 1.85, implying the presence of mosaic monosomy X. However, the QF-PCR and FISH results were nearly normal. In uncultured amniotic fluid, CMA and rapid aneuploidy detection indicated complete monosomy X. Across different sampling points on the aborted fetus, the FISH results varied from normal, to mosaic, and then complete monosomy X. Conclusion: This case presents a rare and complex situation where sampling from uncultured chorionic villi indicated low-level chromosome mosaicism, while sampling from amniotic fluid revealed complete monosomy X. Although some of these discordant outcomes may be due to methodological limitations, we conclude that prenatal consultation should be combined with fetal ultrasound phenotype and genetic testing for a comprehensive evaluation of fetal genetic abnormalities.
An Exceptional Adenocarcinoma in a Girl
Authors: Bangaly Traore, Ibrahima Kalil Cisse, Malick Bah, Ahmed Monzomba Keita
Journal: Case Rep Oncol Med (2018)
MeSH terms: Case Reports

Anal adenocarcinoma is very rare and usually occurs in the elderly. We present a case of a 12-year-old girl with an anal margin painful tumor infiltrating the lower rectum, with perineal and vulvar permeation nodules and bilateral fixed inguinal and iliac lymph nodes. Histology showed anal adenocarcinoma with mucosecreting component and independent cells. She had no extra pelvic metastasis on CT scan. She underwent a colostomy and palliative care. This exceptional case challenges us on the diversity of forms of anal cancers that require a multidisciplinary approach. The precarious social context and the age of onset make it difficult to manage this rare cancer.
Liver angiosarcoma, a rare liver malignancy, presented with intraabdominal bleeding due to rupture--a case report
Authors: Chin-Ying Chien, Cheng-Cheng Hwang, Chun-Nan Yeh, Huang-Yang Chen, Jui-Teng Wu, Chan-Siu Cheung, Chih-Lang Lin, Cho-Li Yen, Wen-Yen Wang, Kun-Chun Chiang
Journal: World J Surg Oncol (2012)
MeSH terms: Abdominal Cavity / pathology, Hemangiosarcoma / complications, Hemorrhage / therapy, Hepatectomy / adverse effects, Liver Neoplasms / complications, Rupture, Spontaneous / complications, Case Reports, Abdominal Cavity / surgery, Aged, 80 and over, Embolization, Therapeutic, Female, Hemangiosarcoma / pathology, Hemangiosarcoma / surgery, Hemorrhage / etiology, Humans, Liver Neoplasms / pathology, Liver Neoplasms / surgery, Treatment Outcome

Liver angiosarcoma is a rare disease, however it still ranks as the third of most common primary liver maligancies. The prognosis of liver angiosarcoma is very poor with almost all patients with this kind of disease die within 2 years after diagnosis. No specific symptoms and signs are closely associated with this disease. Here, we report a case presenting shock status at first due to rupture of liver angiosarcoma- induced internal bleeding. After emergent transarterial embolization (TAE), she received partial hepatectomy two weeks later. 4 months after operation, she is still with a good performance status without obvious recurrence or metastasis identified.
Epidural cavernous haemangioma during pregnancy: a case report and a literature review
Authors: Anas Bennis, Reda Hafiane, Jaafar Benouhoud, Amine El Khaoudi, Khadija Ibahioin, Abdelhakim Lakhdar, Ihsane Moussaid, Smaïl El Youssoufi, Said Salmi
Journal: Pan Afr Med J (2019)
Keywords: epidural neoplasms, central nervous system cavernous haemangioma, pregnancy, vascular surgical procedures
MeSH terms: Epidural Neoplasms / diagnosis, Hemangioma, Cavernous, Central Nervous System / diagnosis, Pregnancy Complications, Neoplastic / diagnosis, Case Reports, Review, Adult, Epidural Neoplasms / pathology, Epidural Neoplasms / surgery, Female, Hemangioma, Cavernous, Central Nervous System / pathology, Hemangioma, Cavernous, Central Nervous System / surgery, Humans, Magnetic Resonance Imaging, Pregnancy, Pregnancy Complications, Neoplastic / pathology, Pregnancy Complications, Neoplastic / surgery, Prognosis, Spinal Cord Compression / etiology

Cavernous haemangiomas are benign vascular malformations that can locate in the central nervous system. The epidural spinal location remains unusual. Pregnancy is known to be a precipitating factor. The aim of this study is to review general aspects of these lesions and specific facts about their relationship to pregnancy. A 32-year-old full-term pregnant woman is managed during early labor for a progressive spinal cord compression syndrome. After delivery, exploration by a lumbar MRI found an epidural vascular dorsal mass. Surgical exploration and histopathological examination confirmed the diagnosis of epidural cavernous haemangioma. The patient achieved complete recovery after 1 month. Spinal cavernous haemangiomas are rare malformations. Specific mechanisms seems to be involved in their growth during pregnancy. Although clinical and radiological presentation are spectacular and misleading, the prognosis is generally good, and urgent surgical treatment during pregnancy is usually not indicated.
Abdominal pregnancy with a healthy newborn: a new case
Authors: Abderrahim Siati, Taher Berrada, Aziz Baidada, Aicha Kharbach
Journal: Pan Afr Med J (2019)
Keywords: abdominal pregnancy, hemorrhage, laparotomy, term
MeSH terms: Abdomen / surgery, Placenta / metabolism, Pregnancy Outcome, Pregnancy, Abdominal / diagnosis, Case Reports, Female, Gestational Age, Humans, Hysterectomy, Infant, Newborn, Laparotomy, Pregnancy, Term Birth

Abdominal pregnancy is a rare form of ectopic pregnancy with very high morbidity and mortality for both the mother and the fetus. Diagnosis and management can pose some difficulties especially in low-resource centers. We report a case of abdominal pregnancy with a healthy newborn. A 34-year-old Moroccan woman, G4P3 (3 alive children), presented with shortness of breath and progressive abdominal distension and pain at 37 weeks' gestation. An emergency laparotomy was performed with the impression of abdominal pregnancy. Intraoperatively, the fetus was seen in an intact amniotic sac in her abdomen, the placenta was strongly adhered to the fundus and enveloped the left adnexa. A total hysterectomy with a left adnexectomy was performed. The patient and neonate progressed well and were discharged. Term abdominal pregnancy is an extremely rare diagnosis. The life-threatening complication is bleeding from the detached placental site. High index of suspicion is vital in making prompt diagnosis in such situations.