OpenMed/multicare-articles huggingface dataset:
A Diagnostic Dilemma of Recurrent Disseminated Peritoneal Leiomyomatosis with Hypertrophied Omental Vessels: Imaging and Embolization of Omental Branches with Positive Outcome
Authors: Jitendra Parmar, Chander Mohan, Deepak Hans, Maulik Vora
Journal: Case Rep Obstet Gynecol (2017)
MeSH terms: Case Reports

We present a case report of recurrent disseminated peritoneal leiomyomatosis in a 30-year-old female with a past history of laparoscopic myomectomy by a technique of morcellation for a large fibroid in 2014. After one year she presented in 2015 with a well-defined oval shaped fibroid along the anterior abdominal wall, which was supplied by the 10th intercostal artery and a branch of right internal mammary artery. She was again presented after 1 year in 2016 with a large pelvic-abdominal fibroid with blood supply from the omental artery, a branch from the right gastroepiploic artery, and sigmoid branches of inferior mesenteric artery.
Pleural effusion and acute right heart failure due to a ruptured right sinus of Valsalva aneurysm and correction by surgical intervention
Authors: Jianmei Li, Qing Li, Yan Shen, Lihong Zhang, Chunmei Zhang, Tao Guo, Zihong Guo
Journal: J Cardiovasc Thorac Res (2020)
Keywords: acute right-sided heart failure, pleural effusion, sinus of valsalva aneurysm
MeSH terms: Case Reports

In the study, we present the case of a 65-year-old male with rupture of right SVA into the right atrium that caused pleural effusion and acute right-sided heart failure (ARHF), which corrected by surgical intervention.
Evidence-based guideline implementation of quality assurance and quality control procedures in the Saudi National Mental Health Survey
Authors: Sanaa Hyder, Lisa Bilal, Luma Akkad, Yu-Chieh Lin, AbdulHameed Al-Habeeb, Abdullah Al-Subaie, Mona Shahab, Abdulrahman Binmuammar, Feda Al-Tuwaijr, Noha Kattan, Yasmin Altwaijri
Journal: Int J Ment Health Syst (2017)
Keywords: epidemiology, mental health, quality control, survey, survey methodology

Background:
The World Mental Health surveys have been known to apply high standards of quality control, but few studies have been published to document this. Furthermore, the effectiveness of quality control has rarely been reported in the Middle East.
Case presentation:
The focus of this paper was to highlight the implementation of quality control procedures in the Saudi National Mental Health Survey under the World Mental Health Survey Consortium. The paper summarizes the guidelines implemented for the various phases of survey quality control-the quality assurance procedures, the quality control procedures and the quality control appraisal components-as per previously prescribed recommendations in literature.
Conclusions:
Survey quality management is a process and not reducible to a single event. Midstream corrections are warranted by detecting problems and intervening appropriately. The Saudi National Mental Health Survey implemented such procedures through continuous quality improvement.
Colonic Intramural Hematoma in a Cat: A Case Report
Authors: Ti-Chiu Hsu, Lee-Shuan Lin, Cheng-Shu Chung, Chuan Chiang, Hsien-Chieh Chiu, Ping-Hsun Huang
Journal: Front Vet Sci (2022)
Keywords: cat, colonic intramural hematoma, colonoscopy, computed tomography, ultrasonography
MeSH terms: Case Reports

Colonic intramural hematoma is a rare condition in humans and companion animals. Its clinical presentation in cats has not previously been reported. An 8-year-old male American shorthair cat presented with acute onset of constipation and anorexia for 3 days. Laboratory examination indicated mild elevation of alanine aminotransferase, globulin, and total protein levels. Complete blood count was normal. Radiographs revealed a soft tissue opacity mass located caudodorsally to the urinary bladder, causing narrowing of the descending colonic lumen. Sonography showed a heteroechogenic intraluminal mass containing liquefied content between the submucosal and muscular layers of the descending colon. On computed tomographic images, the mass contained two different attenuated contents with an interface. Colonoscopy was then performed for intestinal biopsy, and the contents observed in the intraluminal mass were drained via surgical evacuation and considered as blood clots. Supportive medical treatment, including antibiotics and fecal softener, was administered, and the clinical signs resolved uneventfully. Mild chronic proctitis without apparent malignancy was confirmed histopathologically, and no recurrence was observed after more than 14 months, and thus a colonic intramural hematoma was presumptively diagnosed. The information provided by multimodal imaging of the mass was essential for the diagnosis and determination of the treatment in this case.
Novel compound heterozygous variants of SLC12A3 gene in a Chinese patient with Gitelman syndrome: a case report
Authors: Wenqing Chen, Qin Zhou, Hongjun Chen, Heng Li, Jianghua Chen
Journal: Front Genet (2023)
Keywords: gitelman syndrome, slc12a3 gene, clinical characteristics, gene mutation, whole-exome sequencing
MeSH terms: Case Reports

Background: The Gitelman syndrome (GS) is an autosomal recessive disorder of renal tubular salt handling. Gitelman syndrome is characterized by hypokalemia, metabolic alkalosis, hypomagnesemia, hypocalciuria, and renin-angiotensin-aldosterone system (RAAS) activation, and is caused by variants in the SLC12A3 gene. Gitelman syndrome has a heterogeneous phenotype, which may or may not include a range of clinical signs, posing certain difficulties for clinical diagnosis. Case presentation: A 49-year-old man was admitted to our hospital due to muscular weakness. The patient's history revealed previous recurrent muscular weakness events associated with hypokalemia, featured by a minimum serum potassium value of 2.3 mmol/L. The reported male patient had persistent hypokalemia, hypocalciuria and normal blood pressure, without presenting obvious metabolic alkalosis, growth retardation, hypomagnesemia, hypochloremia or RAAS activation. We performed whole-exome sequencing and identified a novel compound heterozygous variant in the SLC12A3 gene, c.965-1_976delGCGGACATTTTTGinsACCGAAAATTTT in exon8 and c.1112T>C in exon9 in the proband. Conclusion: This is a study to report a heterogeneous phenotype Gitelman syndrome with a novel pathogenic compound heterozygous variant in the SLC12A3 gene. This genetic study expands the variants spectrum, and improve the diagnostic accuracy of Gitelman syndrome. Meanwhile, further functional studies are required to investigate the pathophysiological mechanisms of Gitelman syndrome.
Severe Hyponatremia in the Setting of COVID-19-Associated Syndrome of Inappropriate Antidiuretic Hormone: A Case Report
Authors: Jorge A Gutierrez, David Ritzenthaler, Angeline Sawaya, Amanda L Pensiero
Journal: Cureus (2023)
Keywords: acute hyponatremia, covid 19, covid-19 retro, hyponatremia, syndrome of inappropriate antidiuretic hormone secretion
MeSH terms: Case Reports

The COVID-19 pandemic has resulted in significant worldwide morbidity and mortality. One of the less studied clinical manifestations is Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) associated with COVID-19 pneumonia. We present a single case of COVID-19 pneumonia-associated SIADH in a 71-year-old male with a history of alcohol use disorder. This case highlights the importance of full diagnostic workup of the underlying cause of hyponatremia to avoid significant morbidity.
Main Bronchus Penetration by Thoracostomy Tube: A Rare Inadvertent Complication
Authors: Parviz Mardani, Reza Shahriarirad, Amirhossein Erfani, Keivan Ranjbar, Bizhan Ziaian, Armin Amirian, Hamed Ghoddusi Johari
Journal: Bull Emerg Trauma (2021)
Keywords: bronchial injury, chest tube, main bronchus, misplacement, thoracostomy tube
MeSH terms: Case Reports

Tube thoracostomy has been known to be a common and invasive, however not innocuous, procedure which is often life-saving. Though, numerous complications have been reported during executing this procedure. In this report, we describe a 27-year-old woman, case of multiple trauma due to car collision that was transferred to our service due to severe right side chest tube air leak and subcutaneous emphysema in which after proper evaluation, it was revealed that the chest tube crossed through the right pleural cavity and penetrated the bronchus intermedius. A literature search failed to identify a similar case. The misplacement was confirmed by fiber optic bronchoscopy and after surgical and intensive care management of the patient, she was discharged with an uneventful post-op course. This case noticeably determines that bearing in mind the extreme risks and the careful checks of the tube location are required, particularly in trauma patients, even in the absence of anatomical abnormalities.
Safety and Efficacy of Insulin and Heparin in the Management of Hypertriglyceridemia-Induced Pancreatitis in a Patient without Diabetes: A Case Report
Authors: Luis Tolento Cortes, Jessica Trinh, Mimi Le, Philip Papayanis, Leah Tudtud-Hans, Lisa Hong
Journal: Case Rep Endocrinol (2022)
MeSH terms: Case Reports

Acute pancreatitis (AP) leads to a variety of complications, such as local or systemic inflammatory responses as well as organ failure. While choledocholithiasis and alcohol abuse are two of the most common causes of AP, hypertriglyceridemia causes AP with an incidence rate between 2 and 5%. The management of hypertriglyceridemia-induced pancreatitis (HTGIP) is focused on the lowering of triglyceride (TG) levels, and the efficacy of therapies for the management of HTGIP may vary based on the hypertriglyceridemia etiology. The aim of this article is to report a case of a 43-year-old female with a history of familial hypertriglyceridemia and without diabetes who was admitted for acute pancreatitis with a TG level elevated to 4,435 mg/dL. The patient was treated with a combination of insulin, heparin, atorvastatin, and omega-3-acid ethyl esters, and her TG level was reduced to 880 mg/dL after 9 days of therapy. Despite the successful treatment of the patient, standardization of the approach for the treatment of HTGIP is needed. Future research should aim to identify the appropriateness of insulin therapy specifically in patients without diabetes presenting with hypertriglyceridemia and the dosing associated with optimal safety.
Primary osteosarcoma of the right heart ventricle and atrium; a case report
Authors: Terje Forslund, John Melin, Anders Seppä
Journal: Clin Med Oncol (2008)
Keywords: computerized tomography, primary heart osteosarcoma, ultrasound
MeSH terms: Case Reports

Most primary malignancies of the heart, among them also osteosarcoma are found in the left and very uncommonly in the right ventricle. We report a 75-year-old patient with a primary osteosarcoma sited in the right ventricle occluding the pulmonary outflow. The diagnosis was made when the patient was alive, using echocardiography and computerized scan tomography examinations. Like in previous reports on such malignancies, it was far too late for surgical or other therapeutic interventions, and the histological diagnosis was made post mortem.
Creeping attachment involving dental implants: two case reports with a two-year follow-up from an ongoing clinical study
Authors: Armando R Lopes Pereira Neto, Bernardo Born Passoni, José Moisés de Souza Jr, João Gustavo Oliveira de Souza, César Augusto Magalhães Benfatti, Ricardo de Souza Magini, Marco Aurélio Bianchini
Journal: Case Rep Dent (2014)

Introduction. This paper describes case reports where coronal growth of soft tissue on implant threads was observed after surgery for soft tissue graft. This phenomenon is known as "creeping attachment." Methods. Two patients were submitted to gingival graft procedure including subepithelial connective tissue graft and masticatory mucosal graft. A two-year follow-up appointment was performed. Results. After a two-year follow-up gingival growth over titanium surfaces characterizing the "creeping attachment" phenomenon was observed. This gingival growth happened over abutment and threads surfaces. Conclusion. The creeping attachment phenomenon is possible over titanium surfaces and has not yet been reported in the relevant literature over this kind of structure.
Carglumic Acid Contributes to a Favorable Clinical Course in a Case of Severe Propionic Acidemia
Authors: Jun Kido, Shirou Matsumoto, Kimitoshi Nakamura
Journal: Case Rep Pediatr (2020)
MeSH terms: Case Reports

Propionic acidemia (PA) is manifested as an abnormal accumulation of propionic acid and its metabolites, including methylcitrate, 3-hydroxypropionic acid, and propionylglycine, and is caused by a defect of propionyl-CoA carboxylase. PA is complicated by acute life-threatening metabolic crises, which are precipitated by a catabolic state and result in multiple organ failure or even death, if untreated. A neonate with PA recovered from the first metabolic crisis 3 days after birth but developed a second metabolic crisis during the recovery phase. This patient was considered to have severe PA and was accordingly given carglumic acid treatment in combination with carnitine supplementation and protein restriction, which was expected to prevent a recurrent metabolic attack. The patient did not develop hyperammonemia after receiving carglumic acid and was never hospitalized. Moreover, she did not present with acidosis even during viral infection. At 26 months of age, she led a stable life while receiving carglumic acid and regular rehabilitation. Carglumic acid treatment in combination with carnitine supplementation and protein restriction prevented metabolic decompensation, which would have otherwise required hospitalization, and resulted in improved quality of life and developmental outcomes.
Replacement of Congenitally Missing Maxillary Lateral Incisor with Two-Buccal-Retainer Resin-Bonded Fixed Dental Prosthesis Modified by Proximal Boxes
Authors: Lama Marmar, Safaa Bassam Shihabi, Issam Jamous
Journal: Case Rep Dent (2022)
MeSH terms: Case Reports

A 21-year-old male patient with congenitally missing maxillary right lateral incisor presented to Fixed Prosthodontics Department at the Faculty of Dentistry, Damascus University (Damascus, Syria). A two-buccal-retainer lithium disilicate glass-ceramic resin-bonded fixed dental prosthesis (RBFDP) was chosen to replace the missing tooth. This clinical report describes a novel preparation design of two-buccal-retainer lithium disilicate glass-ceramic RBFDP modified by proximal boxes. A recall appointment after 3 years showed no fracture, no de-bonding, no secondary caries, and no staining in prosthesis margins. Color matching with natural teeth was excellent, and the patient was satisfied.
Detection of patent ductus arteriosus with intraoperative transesophageal echocardiography in a patient undergoing closure of coronary artery to pulmonary artery fistula
Authors: Yuka Miyata, Yukio Hayashi
Journal: JA Clin Rep (2017)
Keywords: coronary artery fistulas, patent ductus arteriosus, shunt ratio, transesophageal echocardiography

Background:
Coronary artery to pulmonary artery fistula is an unusual vascular anomaly, and the shunt ratio of this fistula is usually small.
Case presentation:
We report anesthetic management of a 55-year-old female with annuloaortic ectasia, aortic valve regurgitation, and coronary artery to pulmonary artery fistula undergoing radical repair. We calculated the left-to-right shunt ratio after placement of a pulmonary artery catheter and found that the ratio was unexpectedly high. Thus, we explored the presence of another shunt by intraoperative transesophageal echocardiography and found patent ductus arteriosus undiagnosed before operation.
Conclusions:
A combination of a pulmonary artery catheter and transesophageal echocardiography is useful to explore the presence of another shunt, such as patent ductus arteriosus during anesthesia.
Dramatic increase in volume versus length of invasive ductal carcinoma mimicking intramammary lymph node in a small nodular lesion
Authors: Seda Aladag Kurt, Varol Celik
Journal: Bull Natl Res Cent (2022)
Keywords: 3d, breast cancer, intramammary lymph node, mammography, screening
MeSH terms: Case Reports

Background:
The tumor growth pattern in breast cancer appears to be variable and unpredictable. A minor increase in size in a pre-existing lesion, especially under 1 cm, corresponds to a more pronounced increase in volume.
Case presentation:
We report a 63-year-old woman with a nodular density mimicking intramammary lymph node, diagnosed as invasive carcinoma of luminal B subtype. The lesion increased size and density over time in following mammograms until having indistinct margins. While the tumor volume was 12.7 mm3 at the first observation on mammography, it has increased approximately 6.7 times to reach 85.7 mm3 in four years. Finally, the patient diagnosed with early-stage breast cancer (T1N0M0) was treated with breast-conserving surgery.
Conclusions:
Minor changes in size, density, and margin status of a lesion on serial mammograms are warning for breast cancer. Withal, a slight increase in lesion size in two dimensions can result in significant differences in volume. Therefore, comparative evaluation with previous mammograms and observing any difference in morphological features by screening are crucial for early diagnosis and optimal management of the disease.
Delayed Oxaliplatin-Related Severe Neurotoxicity in Metastatic Colorectal Cancer: A Case Report
Authors: Yohei Iimura, Naoki Furukawa, Seiichiro Kuroda
Journal: Cureus (2023)
Keywords: chemotherapy, coasting phenomenon, colorectal cancer, oxaliplatin, peripheral neuropathy
MeSH terms: Case Reports

In patients receiving oxaliplatin-based chemotherapy, resulting in frequent peripheral neuropathy and requiring long-term management, anticancer drug-induced platinum-based peripheral neuropathy (mixed motor, sensory, and autonomic neuropathy) can result in the coasting phenomenon in which the symptoms worsen temporarily after two to three weeks, even after the cessation of the drug. The coasting phenomenon is difficult to manage due to the unpredictable nature of the symptoms. We encountered a patient with grade 3 peripheral neuropathy that developed rapidly in the second cycle after the treatment to switch from mFOLFOX6/bevacizumab to FOLFIRI/aflibercept. Supportive care with duloxetine was unsuccessful in this patient. Herein, we report the case.
Idiopathic Spontaneous Occurrence of Heterotrophic Occurrence During Pregnancy
Authors: Christina Melian, Aadit Shah, Emaan Alvi, Brendan Boyce, Fazel Khan, James Penna
Journal: J Am Acad Orthop Surg Glob Res Rev (2023)
MeSH terms: Elbow Joint / surgery, Nervous System Diseases, Ossification, Heterotopic / diagnostic imaging, Ossification, Heterotopic / surgery, Case Reports, Female, Humans, Knee Joint, Neoplasm Recurrence, Local, Pregnancy

Heterotopic ossification (HO) typically presents in the hip, knee, and elbow joints in the setting of trauma or postsurgical intervention. Less commonly, it may occur secondary to neurologic dysfunction or underlying genetic conditions, but idiopathic HO is rare. Most cases of HO are managed nonoperatively with surgical resection remaining a controversy due to high recurrence rates. We describe a case of idiopathic HO of the shoulder that occurred in the absence of trauma, neurologic dysfunction, or underlying genetic disorder that was treated with surgical excision.
A rare case of prostate neuroendocrine tumor: A case report
Authors: Shunxing Teh, Fam Xeng Inn, Iqbal Hussain Rizuana, Wan Muhaizan Wm
Journal: Front Oncol (2022)
Keywords: chromogranin a, immunohistochemical markers, prostate neuroendocrine tumor, small cell carcinoma, synaptophysin
MeSH terms: Case Reports

Small cell prostate neuroendocrine carcinoma (SCPC) is a rare and highly aggressive malignant tumor. We present a case of a 52-year-old Iranian man, presenting with complaints of occasional gross hematuria and perineal pain for 6 months. PSA was 0.8 ng/ml. A digital rectal examination found a huge and hard prostate mass. He underwent a transrectal ultrasound-guided (TRUS) biopsy of the prostate. Histopathology showed high-grade small cell neuroendocrine carcinoma. Immunohistochemical markers were positive for synaptophysin with a Ki67 index of almost 100%. However, CD56 and chromogranin A markers were negative. Magnetic resonance imaging (MRI) of the prostate showed a prostate mass with invasion to the rectum, while contrast-enhanced computed tomography of the thorax, abdomen, and pelvis (CT TAP) ruled out metastasis. A multidisciplinary team discussion was carried out, and a decision was made for concurrent chemotherapy and radiation (cisplatin and etoposide for 4 cycles and 70 Gy, 35 fractions). There is a lack of consensus on the management of SCPC. The main modality of management in advanced (stage IV) disease is chemotherapy. It is a highly aggressive tumor with a poor prognosis and is not responsive to hormonal therapy.
Right Heart Transvalvular Embolus with High Risk Pulmonary Embolism in a Recently Hospitalized Patient: A Case Report of a Therapeutic Challenge
Authors: Gyanendra Kumar Acharya, Ajibola Monsur Adedayo, Hejmadi Prabhu, Derek R Brinster, Parvez Mir
Journal: Case Rep Pulmonol (2015)

Thrombus-in-transit is not uncommon in pulmonary embolism but Right Heart Transvalvular Embolus (RHTVE) complicating this is rare. A 54-year-old obese male with recent hospitalization presented with severe dyspnea and collapse. Initial investigations revealed elevated d-dimer and troponin. CTA showed saddle pulmonary embolus and bedside echocardiogram revealed right ventricular (RV) pressure overload and dilatation (RV > 41 mm), McConnell's sign, and mobile echodensity attached to tricuspid valve. Patient was immediately resuscitated and promptly transferred for surgical embolectomy under cardiopulmonary bypass. A long segment of embolus traversing through the tricuspid valve and extensive bilateral pulmonary artery embolus were removed. IVC filter was placed for a persistent right lower extremity DVT. Hypercoagulable work-up was negative. Patient continued to do well after discharge on Coumadin. Open embolectomy offers great promises where there is no consensus in optimal management approach in such patients. Bedside echocardiogram is vital in risk stratification and deciding choice of advanced PE treatment.
Hyperprogressive Disease in Cancers Treated With Immune Checkpoint Inhibitors
Authors: Pan Shen, Liang Han, Xin Ba, Kai Qin, Shenghao Tu
Journal: Front Pharmacol (2021)
Keywords: hyperprogressive disease, immune checkpoint inhibitors, immunotherapy, predictive biomarker, pseudoprogression
MeSH terms: Review

Immunotherapy, which takes advantage of the immune system to eliminate cancer cells, has been widely studied and applied in oncology. Immune checkpoint inhibitors (ICIs) prevent the immune system from being turned off before cancer cells are eliminated. They have proven to be among the most promising and effective immunotherapies, with significant survival benefits and durable responses in diverse tumor types. However, an increasing number of retrospective studies have found that some patients treated with ICIs experience unusual responses, including accelerated proliferation of tumor cells and rapid progression of the disease, with poor outcomes. Such unexpected adverse events are termed hyperprogressive disease (HPD), and their occurrence suggests that ICIs are detrimental to a subset of cancer patients. HPD is common, with an incidence ranging between 4 and 29% in several cancer types. However, the mechanisms of HPD remain poorly understood, and no clinical predictive factors of HPD have been identified. In this review, we summarize current findings, including retrospective studies and case reports, and focus on several key issues including the defining characteristics, predictive biomarkers, potential mechanisms of HPD, and strategies for avoiding HPD after ICI treatment.