OpenMed/multicare-articles huggingface dataset:
Mapping social movements momentum: unveiling networks in the movement for the right to abortion in Mexico
Authors: Cesángari López Martínez, Allison Sambo, Diana Medina González
Journal: Front Res Metr Anal (2024)
Keywords: mexico, abortion, intersectional feminisms, movement mapping, social movements, social network analysis, surveys

In this case study, we propose a network analysis approach to map social movements through an intersectional feminist lens. We aim to gain a more in-depth understanding of movements' network structures to examine the roles and relationships of movement actors, the flow of resources between them, and potential areas of collaboration and conflict. By incorporating Social Network Analysis (SNA) techniques and visually mapping dynamics within social movements, this approach can assess the significance of small actors in creating change and stresses the need for their perspectives to be heard. Furthermore, our methodology adopts a feminist intersectional framework that recognizes the role of different identities in shaping the movement and its actors. To demonstrate the practical application of this approach, we examined the movement for the right to abortion in Mexico between September and December 2021. Our multi-step process included (1) designing a survey tool adapted to the context of the movement, (2) collecting and analyzing survey responses on movement actors' relationships and interactions, including their priorities, activities, needs, risks, and challenges, (3) visualizing the network using SNA techniques that account for the complexity and diversity of the movement, (4) interpreting the findings through insights collected in semi-structured interviews and validation meetings with key movement actors, and (5) implementing safety and security guidelines to safeguard the identity of individuals whose activities could put them at risk of suffering institutional, emotional, and physical violence. Our case study offers valuable insights that not only encourage the integration of feminist and intersectional perspectives into data collection processes but also provide a roadmap for accompanying social movements and supporting meaningful and contextually responsive activities.
Transient Lactic Acidosis and Elevation of Transaminases after the Introduction of Remdesivir in a Patient with Acute Kidney Injury
Authors: Elise André, Florian Lemaitre, Marie-Clémence Verdier, Vincent Haufroid, João Pinto Pereira, Philippe Hantson
Journal: Case Rep Crit Care (2024)
MeSH terms: Case Reports

A 56-year-old woman was transferred to the intensive care unit (ICU) two days after an allogeneic stem cell transplantation (ASCT) when she presented acute respiratory distress due to the relapse of a SARS-CoV-2 infection. Following that, she received two intravenous doses of 100 mg remdesivir. Subsequently, the patient developed multiple instances of diarrhea, progressing to oliguria and acute kidney injury, necessitating continuous venovenous hemofiltration (CVVH). Despite the absence of signs of hypoxemia or cardiocirculatory failure requiring vasopressor intervention, a progressive lactic acidosis emerged. Two days after the onset of lactic acidosis, a significant rise in aminotransferases and lactate dehydrogenase occurred, in the absence of encephalopathy and coagulation disorders. Remdesivir therapy had been interrupted upon the initial signs of lactic acidosis. Despite an improvement in liver function tests and lactic acidosis, the patient's condition deteriorated, ultimately leading to her demise on day 29 due to newly arising hematological complications.
Case report: Endoscopic endonasal transposterior clinoid approach for resection of posterior clinoid process meningioma: technical notes and literature review
Authors: Steven Awyono, Kazuhito Takeuchi, Eiji Ito, Yuichi Nagata, Nyoman Golden, Tjokorda Gde Bagus Mahadewa, Ryuta Saito
Journal: Front Oncol (2024)
Keywords: endoscopic endonasal, posterior clinoid process meningioma, posterior clinoidectomy, technical notes, transposterior clinoid approach
MeSH terms: Case Reports

Background:
Posterior clinoid process (PCP) meningioma is an exceedingly rare entity. It remains the most challenging skull base lesion for neurosurgeons due to its treacherous location that insinuates amongst critical neurovascular structures. This article will describe the technical notes using the endoscopic endonasal approach that provide the earliest devascularization and detachment of the tumor PCP meningioma.
Methods:
We are introducing the surgical implementation of an endoscopic endonasal approach to removing PCP meningioma. Furthermore, we perform a literature review of posterior clinoid process meningioma that undergoes surgical intervention, then summarize the benefits and limitations of each approach.
Results:
We present a case of right PCP meningioma that was removed using an endoscopic endonasal approach through the transposterior clinoid corridor in a 52-year-old-woman. We describe the technical notes in performing this approach to have the earliest devascularization and detachment of the tumor by performing posterior clinoidectomy. Safe tumor removal is performed with a wide and clear view of the surrounding neurovascular structure. Based on our database search, we found nine articles reported on the surgical management of PCP meningiomas, with a total number of 15 cases. All of the reported cases performed the tumor removal using the transcranial approach.
Conclusion:
The endoscopic endonasal transposterior clinoid approach circumvents all disadvantages faced by the traditional transcranial approach, providing the earliest approach to devascularized and detaching the tumor from its attachment at PCP. This approach demonstrates safety and efficacy, making it an acceptable alternative for PCP meningioma resections.
Case Report: Taking action or standing by: managing a preterm neonate at the risk of neonatal varicella by metagenomic next-generation sequencing
Authors: Haiting Li, Xiyang Chen, Jie Li, Linlin Chen, Xixi Liu, Caie Chen, Dengpan Xie, Yunqin Chen, Junhui Yuan, Enfu Tao
Journal: Front Pediatr (2024)
Keywords: diagnosis, infection, metagenomic next-generation sequencing, neonatal varicella, prediction
MeSH terms: Case Reports

Neonatal varicella is indeed a rare condition, and most infants born to mothers with varicella have a good prognosis. However, in exceptional cases, neonatal varicella can be life-threatening, particularly for preterm infants. Therefore, it is vital to make an early diagnosis or predict the risk of neonatal varicella to ensure prompt treatment and improve prognosis. This report made an effort to early predict neonatal vericalla by using metagenomic next-generation sequencing (mNGS) in a preterm infant who was at risk for vericalla infection. A preterm infant born from a mother with varicella with symptom onset at 8 days before delivery, putting the infant at risk for varicella infection. Importantly, the patient develop pneumonia and pneumothorax, and neonatal vericella was suspected. Fortunately, the use of mNGS for testing the varicella gene in the serum promptly ruled out varicella zoster virus (VZV) infection in the patient, as indicated by a negative mNGS result. Subsequent follow-up, which included a 14-day stay in the hospital followed by an additional 7 days at home, confirmed this finding. Throughout this period, the patient did not exhibit any rash or other symptoms associated with varicella. Therefore, the novel approach of using mNGS allows neonatologists to predict and promptly address potential neonatal infections. This early detection is crucial, as delayed diagnosis or treatment could pose life-threatening risks, as exemplified by the case of neonatal varicella. In such cases, neonatologists can take proactive measures instead of standing by for at-risk neonates. Furthermore, given the severity of neonatal varicella as a life-threatening condition, the early exclusion of subsequent varicella infection by mNGS can offer reassurance to both family members and healthcare professionals.
Perceived Conjunctival Foreign Material Egress in Morgellons Disease: A Case Study
Authors: Sean Ghiam, Badal Sojitra, Collin Reiff, Connie M Sears, Justin N Karlin
Journal: Case Rep Psychiatry (2024)
MeSH terms: Case Reports

The purpose of this report is to present a case of a 63-year-old man with orbital Morgellons disease. A 63-year-old man presented reporting 15 years of daily egress of different foreign bodies apparently found in the superior fornices of both eyes, exhibiting a classic manifestation known as the matchbox sign. He described the symptoms starting after a facial trauma. The patient stated that at several points over the 15-year course of his condition, he was so distressed that he had contemplated suicide. On multiple exams by a range of ophthalmic professionals, there was no evidence of foreign body. Further investigation involving MRI and plain radiographs demonstrated similar lack of findings. A trial of gabapentin was performed without improvement in symptoms. He discontinued care 5 months later. Morgellons disease is a poorly understood condition, particularly ophthalmic presentations of the disease. Despite extensive investigation, the exact cause of Morgellons disease remains unclear, and there is no definitive treatment for the condition. We highlight the importance of empathetic listening in building trust, as a means of helping the patient to seek psychological help.
Case report: Escitalopram-associated lower limb edema
Authors: Mohamed Hassan Ahmed, Mena Al-Kubaisi, Safa Abdulmajeed Al-Rawi, Omar Hosam Salama, Hebah Mahmoud Abutayyem
Journal: Front Psychiatry (2024)
Keywords: ssris, drug-associated, edema, escitalopram, side effects
MeSH terms: Case Reports

Escitalopram is widely prescribed for the treatment of major depressive disorder and generalized anxiety disorder with a well-documented side effects profile. Peripheral edema, however, is a rarely reported adverse reaction that warrants further work up. This paper summarizes the case of a 58-year female patient who developed transient bilateral peripheral edema following the administration of low dose escitalopram. This case underscores the necessity for clinicians to be familiar with even rare potential side effects of commonly prescribed medications. It also suggests a need for patient education regarding the importance of reporting new symptoms promptly.
Case Report: Superior mesenteric artery vasculitis causing aneurysm following COVID-19 infection
Authors: Minju Kim, Jeong Hee Han, Jung Bum Choi, Byoung Chul Lee, Hyuk Jae Jung
Journal: Front Surg (2024)
Keywords: covid-19, aneurysm, arteritis, steroid, superior mesenteric artery
MeSH terms: Case Reports

Objective:
Arteritis refers to all infectious and non-infectious conditions that lead to inflammation of the arterial wall. However, little is known about its presence in patients with coronavirus disease 2019 (COVID-19). Most patients improved with steroids along with conservative treatments in a few studies. We report our experience with superior mesenteric artery (SMA) arteritis causing an aneurysm following COVID-19 infection.
Case presentation:
A 66-year-old female patient who was infected with COVID-19 1 month prior presented with abdominal pain. A computed tomography scan revealed proximal SMA arteritis. Although preliminary antibacterial treatment was initiated, the follow-up CT revealed an aggressive and fast-growing 5.7-cm SMA aneurysm. Subsequently, an open interposition bypass of the SMA aneurysm was performed successfully. As the specimens retrieved during surgery showed no bacterial colonization in the tissue or blood cultures, the patient was discharged without complications.
Conclusions:
The mechanism of arteritis in patients with COVID-19 has not been elucidated. In the absence of evidence of bacterial infection in arteritis, it is necessary to consider the possibility of viral infection caused by COVID-19 during the COVID-19 pandemic era and start with high-dose steroid therapy promptly.
Case Report: A case of Crohn's disease with right atrial thrombosis
Authors: Zehang Hu, Yi Gao, Shumin Fan
Journal: Front Pediatr (2024)
Keywords: crohn’s disease, children, contrast-enhanced ultrasound, echocardiography, right atrial thrombosis
MeSH terms: Case Reports

Crohn's disease (CD) is a chronic, non-specific inflammatory disease of the intestinal tract with an unknown etiology. It presents with clinical symptoms such as abdominal distension, abdominal pain, diarrhea, bloody stools containing mucus or pus, and other manifestations. CD has a prolonged and chronic course and can lead to various complications that significantly impact patients' quality of life. Patients with CD have hypercoagulable blood and are prone to thromboembolic diseases, which pose a serious threat to their lives. Several studies have indicated that inflammatory bowel disease is a risk factor for venous thromboembolism. The pathogenesis involves abnormalities in the coagulation-anticoagulation system, fibrinolytic system, platelets, vascular endothelial dysfunction, as well as the effects of therapeutic agents. In this case report, we present a rare case of a 15-year-old female patient with active CD complicated by the presence of a right atrial thrombus. Laboratory tests revealed abnormalities in both the coagulation-anticoagulation system and fibrinolysis system in the patient. The initial diagnosis, based on transthoracic echocardiography and contrast-enhanced echocardiography, confirmed the presence of a thrombus in the right atrium. Subsequent administration of anticoagulant and thrombolytic therapy resulted in gradual reduction in size until complete disappearance, as evidenced by dynamic monitoring. Ultrasound examination is considered as the preferred method for follow-up evaluation in patients with CD due to its ability not only to assess gastrointestinal complications but also to aid early identification of cardiovascular complications, thereby enabling timely intervention and treatment-which remains our primary focus of research and effort.
Case report: Pilomatrix carcinoma with PDL1 expression and CDKN2A aberrant
Authors: Ayinuer Abula, Sheng-Qiang Ma, Sisi Wang, Wei Peng, Xiaming Pei, Zhe-Yu Hu
Journal: Front Immunol (2024)
Keywords: cdkn2a, pd1, pdl1, chemotherapy, pilomatrix carcinoma
MeSH terms: B7-H1 Antigen / genetics, B7-H1 Antigen / metabolism, Cyclin-Dependent Kinase Inhibitor p16 / genetics, Pilomatrixoma / genetics, Pilomatrixoma / pathology, Skin Neoplasms / genetics, Skin Neoplasms / pathology, Case Reports, Hair Diseases / genetics, Hair Diseases / pathology, Humans, Male, Middle Aged, Mutation, Cyclin-Dependent Kinase Inhibitor p16, CDKN2A protein, human, B7-H1 Antigen, CD274 protein, human

Case report:
A 55-year-old male patient developed a mass in the left inguinal area with left lower limb swelling and first visited a local hospital 3 months earlier because of unrelieved pain. An MRI scan suggested left suprapubic branch and left acetabular bone destruction, abnormal soft tissue signals within the iliopsoas muscle of the anterior edge of the left iliac bone, and enlarged lymph nodes in the left iliac fossa and left inguinal region. The patient subsequently underwent left pelvic lesion open biopsy and inguinal lymph node resection biopsy. According to pathological reports, the left inguinal mass was considered to be a malignant tumor of cutaneous accessory origin (pilomatrix carcinoma) with extensive vitreous changes. The suprapupubis branch mass was considered to be a bone metastatic pilomatrix carcinoma. Immunohistochemistry (IHC) revealed a PDL1 combined positive score (CPS) of 8. DNA next-generation sequencing (NGS) showed CDKN2A L65Rfs*53 mutation. The patient received three cycles of gemcitabine and nedaplatin. However, the lesion progressed.
Conclusion:
Chemotherapy is not effective for treating pilomatrix carcinoma. PDL1 antibodies and CDK4/6 inhibitors might be treatment options for pilomatrix carcinoma.
Continuous hemodynamics monitoring during arteriovenous malformation microsurgical resection with laser speckle contrast imaging: case report
Authors: Alexis Dimanche, David R Miller, Johannes Goldberg, Andreas Raabe, Andrew K Dunn, David Bervini
Journal: Front Surg (2023)
Keywords: arteriovenous malformation, blood flow imaging, case report, cerebral blood flow, continuous imaging, hemodynamics, laser speckle contrast imaging (lsci)
MeSH terms: Case Reports

AVM surgery is challenging due to progressive and often unforeseeable flow changes during its resection which involve both the AVM and the surrounding brain tissue. Hence, accurate monitoring of blood flow is crucial to minimize complications and improve outcomes. The following case report illustrates the usefulness of complimentary non-invasive tools that can provide real time blood flow assessment. We present a case demonstrating the application of laser speckle contrast imaging (LSCI) in evaluating vessel flow dynamics during AVM surgery. A 30-year-old female presented with sudden headaches, nausea, vomiting, and vertigo. Emergency imaging revealed a ruptured cerebellar AVM necessitating surgical intervention. LSCI was integrated into the surgical workflow, providing continuous visualization of relative cerebral blood flow (rCBF) of vessels surrounding the AVM. Before AVM resection, LSCI measurements revealed the arterialized vasculature supplying the AVM nidus; measurements after AVM resection showed significant hemodynamic changes including normal flow in the initially arterialized AVM draining veins and adjacent arterial branches. LSCI also detected blood flow alterations during temporary occlusion, enabling assessment of downstream vascular regions. In conclusion, we provide an example supporting the utility of LSCI for real-time hemodynamic monitoring during AVM resection surgery. LSCI offers non-invasive, continuous, and immediate blood flow information, complementing conventional imaging methods like indocyanine green angiography. Additionally, our findings suggest that LSCI has the potential to provide a non-invasive means of identifying the specific superficial vessel branches or cortical areas that receive blood supply from a particular vessel.
Reoperation-requiring postoperative intracranial haemorrhage after posterior fossa craniotomy: Retrospective case-series
Authors: Elise K Kristensen, Kay Müller, Tor Ingebrigtsen, Haakon Lindekleiv, Roar Kloster, Jørgen G Isaksen
Journal: Brain Spine (2023)
Keywords: craniectomy, craniotomy, monitoring, posterior fossa, postoperative complications, postoperative haemorrhage

Introduction:
Studies report rates of treatment-requiring postoperative intracranial haemorrhage after craniotomy around 1-2%, but do not distinguish between supratentorial and posterior fossa operations. Reports about intracranial haemorrhages' temporal occurrence show conflicting results. Recommendations for duration of postoperative monitoring vary.
Research question:
To determine the rate, temporal pattern and clinical presentation of reoperation-requiring postoperative intracranial posterior fossa haemorrhage.
Material and methods:
This retrospective case-series identified cases operated with posterior fossa craniotomy or craniectomy between January 1, 2007 and December 31, 2021 by an electronic search in the patient administrative database, and collected data about patient- and treatment-characteristics, postoperative monitoring, and the occurrence of haemorrhagic and other serious postoperative complications.
Results:
We included 62 (n = 34, 55% women) cases with mean age 48 (interquartile range 50) years operated for tumours (n = 34, 55%), Chiari malformations (n = 18, 29%), ischemic stroke (n = 6, 10%) and other lesions (n = 3, 5%). One (2%) 66-year-old woman who was a daily smoker operated with decompressive craniectomy and infarct resection, developed a reoperation-requiring postoperative intracranial haemorrhage after 25.5 h. In four (6%) cases, other serious complications requiring reoperation or transfer from the post anaesthesia care unit or regular bed wards to the intensive care unit occurred after 0.5, 6, 9 and 54 h, respectively.
Discussion and conclusion:
Treatment-requiring postoperative intracranial haemorrhage and other serious complications after posterior fossa craniotomies occur over a wide timespan and are difficult to capture with a standardized postoperative monitoring time. This indicates that the duration of monitoring should be individualized based on assessment of risk factors.
JAK1 inhibitor abrocitinib for the treatment of steroid-induced rosacea: case series
Authors: Bingyang Xu, Zining Xu, Shuhong Ye, Hong Sun, Bin Zhao, Na Wu, Jiawen Wu
Journal: Front Med (Lausanne) (2023)
Keywords: jak1 inhibitor, abrocitinib, case series, dermatology treatment, steroid-induced rosacea
MeSH terms: Case Reports

Background:
Steroid-induced rosacea is a severe withdrawal reaction which can occur after the frequent and excessive topical use of steroids on the face. The Janus kinase (JAK)-signal transducers and activators of transcription signaling pathway is involved in many biological processes and may play a role in the development of steroid-induced rosacea.
Objective:
To observe the efficacy and safety of the JAK1 inhibitor abrocitinib in the treatment of steroid-induced rosacea.
Methods:
Four Chinese female patients were treated with orally-administered abrocitinib, a selective JAK1 inhibitor with a good safety profile, for steroid-induced rosacea.
Results:
Abrocitinib treatment resulted in improved skin condition and lowered Dermatology Life Quality Index scores in each of the four patients. No discomfort was reported and no adverse effects were observed.
Conclusion:
The JAK1 inhibitor abrocitinib is a promising potential treatment for steroid-induced rosacea.
Case Report: False aneurysm as a late unusual complication of the aortofemoral bypass graft in a patient with critical leg ischemic symptoms: interesting case
Authors: M P Belfiore, R Zeccolini, P Roccatagliata, L Gallo, A Fabozzi, S Cappabianca
Journal: Front Radiol (2024)
Keywords: computed tomography-angiography, angiography, aortofemoral bypass surgery, lower extremity ischemic symptoms, pseudoaneurysm
MeSH terms: Case Reports

Aortofemoral bypass surgery is a common procedure for treating aortoiliac occlusive disease, also known as Leriche syndrome, which can cause lower extremity ischemic symptoms. Diagnostic imaging techniques play a crucial role in managing pseudoaneurysms (PSAs), with Duplex ultrasound and Computed Tomography-angiography (CTA) being effective tools for early diagnosis. Pseudoaneurysms (PSAs) present as pulsating masses with various symptoms, and prompt intervention is essential to avoid complications. A case report is presented involving an 82-year-old male who underwent aorto-bifemoral bypass surgery and later developed a pseudoaneurysm (PSA) of the left branch. Surgical treatment involved the removal of the pseudoaneurysm (PSA) and graft replacement. Other cases from the literature are also described, emphasizing the rarity and potential severity of non-anastomotic pseudoaneurysms (PSAs) in reconstructive vascular surgery. Periodic screening of patients who undergo reconstructive vascular surgery is crucial to detect pseudoaneurysms (PSAs) early and prevent complications. Asymptomatic pseudoaneurysms (PSAs) can grow significantly and become life-threatening if not identified in a timely manner. Regular post-operative imaging, such as annual Computed Tomography-angiography (CTA) and/or Duplex ultrasound, is recommended to ensure early diagnosis and appropriate management of complications.