OpenMed/multicare-articles huggingface dataset:
The Importance of Histopathological Examination to the Final Diagnosis of Peripheral Odontogenic Tumors: A Case Report of a Peripheral Odontoma
Authors: Marcio Augusto de Oliveira, Bruna Reis, Debora Pallos, Yeon Jung Kim, Paulo Henrique Braz-Silva, Fabiana Martins
Journal: Case Rep Dent (2019)
MeSH terms: Case Reports

A 30-year-old Caucasian man presented with an 18-month history of an asymptomatic calcified mass, located on the buccal side of the alveolar ridge. Medical records did not present any underlying conditions. On intraoral examination, the lesion was located on the right side of the maxilla, showing mucosal fenestration with mineralized tissue measuring approximately 1 cm in diameter. Radiographic examination showed multiple radiopaque masses. Incisional biopsy was performed, and histological analysis revealed a presence of enamel matrix, dentin, and cementum, resembling tooth-like structures. Surgical removal was offered after the diagnostic confirmation of peripheral odontoma, but the patient refused because of the asymptomatic nature of the lesion.
Laparoscopic surgery for primary ovarian and retroperitoneal hydatid disease: A case report
Authors: Qinghua Zhao, Jin Luo, Qin Zhang, Tianyan Leng, Lihua Yang
Journal: Medicine (Baltimore) (2018)
MeSH terms: Echinococcosis / surgery, Laparoscopy, Ovarian Diseases / parasitology, Ovarian Diseases / surgery, Peritoneal Diseases / parasitology, Peritoneal Diseases / surgery, Case Reports, Adult, Female, Humans, Retroperitoneal Space

Rationale:
Cystic echinococcosis (CE) is a parasitic zoonosis caused by echinococcus larvae. Manifestations of the disease include a severe damage to the liver and lung. Damages to the mesentery, omentum, spleen, brain, heart, bone, thyroid, kidney, and uterus are rarely observed. Moreover, primary ovarian and retroperitoneal hydatid disease is extremely rare, and is easily ignored or misdiagnosed.
Patient concerns:
We present a case of CE in a 34-year-old female who presented with an adnexal mass detected by B-ultrasound. Adnexal and retroperitoneal masses were removed by laparoscopic surgery. Postoperative pathological report (retroperitoneal cyst) Echinococcus granulosus.
Diagnoses:
Primary ovarian and retroperitoneal hydatid disease.
Interventions:
The patient received intravenous injection of dexamethasone (10 mg) before cyst resection to prevent allergic reactions and oral albendazole (600 mg BID) for 14 days to prevent relapse postsurgery.
Outcomes:
The patient revealed no recurrence of disease and no reportable significant changes in 3 months.
Lessons:
We present here a case report of CE. This case described herein inhabited a nonendemic region. Gentle and careful operation, and avoiding cyst rupture is the key to insuring success of the surgery. For safety, dexamethasone may be used before cyst resection to prevent anaphylaxis, and mebendazole can be used postoperatively to prevent relapse.
Crescentic Glomerulonephritis and Membranous Nephropathy: A Rare Overlap
Authors: Mohamedanwar Ghandour, Heba Osman, Samer Alkassis, Alix Charles, Kristina Zalewski, Jarrett Weinberger, Yahya Malik-Osman, Zeenat Y Bhat
Journal: Case Rep Nephrol (2022)
MeSH terms: Case Reports

Background:
Membranous nephropathy (MN) is a disease that affects the basement membrane of the glomeruli of the kidney resulting in proteinuria. The concurrent incidence of vasculitic glomerulonephritis and MN in the same patient is unusual. Herein, we report a case with this unusual combination.
Case:
Our patient is a 53-year-old Hispanic male with a medical history of tobacco use, type 2 diabetes mellitus, and hypertension who presented with hematuria and was found to have nephrotic range proteinuria and renal impairment. Blood workup revealed positive ANCA serology, which led to a renal biopsy that showed crescentic vasculitis in addition to membranous nephropathy. The patient was started on intermittent hemodialysis (HD) and treated initially with intravenous (IV) pulse steroids; subsequently, oral prednisolone and IV cyclophosphamide were initiated. The patient remained HD dependent at the time of discharge with the resolution of hematuria. A follow-up with an outpatient nephrology clinic was arranged.
Conclusion:
Membranous nephropathy complicated by crescentic glomerulonephritis has a more aggressive clinical course and decline in renal function compared to MN alone which can lead to initiating renal replacement therapy. However, immunosuppressive drugs can result in significant improvement of renal function if started early enough.
Incorporation of the Altered Cast Technique in the Fabrication Workflow of an Implant-Assisted Removable Partial Denture (IARPD) for an Elderly Patient
Authors: Dimokritos Papalexopoulos, Theodora-Kalliopi Samartzi, Panagiotis Tsirogiannis, Ioli-Ioanna Artopoulou, Nikitas Sykaras
Journal: Case Rep Dent (2023)
MeSH terms: Case Reports

Implants are currently used to serve as abutments for implant-assisted removable partial dentures (IARPDs) to facilitate retention and support of the prosthesis. Implants are proposed in cases of posterior edentulous areas to convert Kennedy Class I or II to Class III or when the preparation of existing teeth to serve as abutments is contraindicated. The purpose of this report is to describe the protocol applied to fabricate an IARPD to restore a Kennedy Class II mandible of an elderly patient by incorporating traditional methods, such as the altered cast technique. Each step of the clinical procedure is thoroughly illustrated to document the selected appointment sequence. The patient was satisfied with the delivered prosthesis that demanded no additional implants to be placed but exploitation of an existing one. IARPDs are a viable and cost-effective solution substantiated by numerous reports with positive effects on patient satisfaction.
Management of general anesthesia in a child with Miller-Dieker syndrome: a case report
Authors: Chiaki Wakiguchi, Kohei Godai, Keika Mukaihara, Tetsuya Ohnou, Tamotsu Kuniyoshi, Mina Masuda, Yuichi Kanmura
Journal: JA Clin Rep (2015)
Keywords: bispectral index, lissencephaly, miller–dieker syndrome

Miller-Dieker syndrome (MDS) is a rare disorder characterized by type I lissencephaly and a distinctive facial appearance that may include prominent forehead, bitemporal hollowing, and micrognathia. MDS is associated with epilepsy. We here report an 18-month-old girl with MDS who required general anesthesia. The child had an extremely low Bispectral Index (BIS) value prior to undergoing general anesthesia. Her perioperative course was uneventful. This case highlights some of the important anesthetic concerns in patients with MDS, which include potentially difficult airways and extremely low BIS values.
Ectodermal dysplasia with amastia: a case of one-step reconstruction
Authors: M Klinger, F Caviggioli, B Banzatti, C Fossati, F Villani
Journal: Case Rep Med (2009)
MeSH terms: Case Reports

Background. Female patients presenting amastia associated with ectodermal dysplasia are not frequently encountered, but they are of great clinical interest and surgically demanding. Traditionally, skin alterations related to Ectodermal Dysplasia have addressed plastic surgeons to perform a two-stage approach in amastia associated with this congenital pathologic condition. This article describes an alternative method for correcting this deformity trough a mammary reconstruction in one surgical stage. Materials and Methods. We report a case of 26-year-old female patient with bilateral amastia associated with ectodermal dysplasia. Amastia in this patient was treated with implantation of subpectoral silicone gel prostheses, without previously breast tissue expansion. Results. At 18 months of follow-up after surgey, there were no complications and excellent cosmetic results were achieved. Patient and surgeon satisfaction was high and the patient underwent a bilateral areola-tattoo. Conclusions. One-stage mammary reconstruction have showed to be a reliable and effective technique also when amastia is associated with Ectodermal Dysplasia, suggesting a still satisfying biomechanical performance of the skin in this pathology.
Fixed drug eruption to sitagliptin
Authors: Mrinal Gupta, Anish Gupta
Journal: J Diabetes Metab Disord (2015)
Keywords: fixed drug eruption, oral provocation test, sitagliptin
MeSH terms: Case Reports

Fixed drug eruption is a common adverse effect seen with various drugs notably antibiotics, antiepileptics and non-steroidal anti-inflammatory drugs. Herein we report a case of Sitagliptin induced fixed drug eruption in a 46 year old female who developed circumscribed, erythematous macules all over the body within one week of initiation of Sitagliptin. The lesions resolved with residual hyperpigmentation on cessation of the drug. The diagnosis was confirmed by an oral provocation test which led to a reactivation of the lesions. To the best of our knowledge, this is the first case of fixed drug eruption to Sitagliptin reported in the literature.
Evolution into Takayasu arteritis in a patient presenting with acute pulmonary oedema due to severe aortic regurgitation; a case report
Authors: Nipun Lakshitha de Silva, Milinda Withana, Praveen Weeratunga, Prakash Priyadharshana, Inoshi Atukorala
Journal: BMC Rheumatol (2018)
Keywords: acute heart failure, aortic regurgitation, infective endocarditis, pulmonary oedema, takayasu arteritis
MeSH terms: Case Reports

Background:
Takayasu arteritis is a rare large vessel vasculitis which predominantly affects young Asian females. Aortic regurgitation and heart failure are well described manifestations which are usually preceded by constitutional symptoms, limb claudication, pulse and blood pressure discrepancies, vascular bruits and features of organ ischaemia.
Case presentation:
A 25-year- old Sri Lankan female presented with a three days history of acute shortness of breath, cough and orthopnoea. On examination she had severe aortic regurgitation resulting in high output cardiac failure. There was no evidence of acute coronary ischaemia or infective endocarditis. The only significant investigation finding was an elevated erythrocyte sedimentation rate (ESR) of 114 mm/first hour. The patient was treated for pulmonary oedema and empirically for infective endocarditis. Extensive evaluation for an underlying infection, large vessel vasculitis or malignancy did not reveal any abnormalities. Detailed periodic assessment identified reduced blood pressure in left arm (70/40 mmHg) compared to right (100/70 mmHg) and reduced pulse volume of left arm with left subclavian bruit more than one year after the initial presentation. Digital subtraction angiography revealed significant stenosis at first part of left subclavian and origin of left vertebral arteries. A diagnosis of Takayasu arteritis was made and patient was started on high dose glucocorticoids.
Conclusions:
Takayasu arteritis can present initially with isolated cardiac involvement even as acute cardiac manifestations and high degree of suspicion with close follow up would allow early detection of development of other classic features and timely diagnosis.
Chronic recurrent multifocal osteomyelitis mimicking a malignant bone tumor: a case report
Authors: Oumnia Bencharef, Tarik Salama, Elmouhtadi Aghoutane, Redouane Elfezzazi
Journal: Pan Afr Med J (2022)
Keywords: chronic recurrent multifocal osteomyelitis, case report, children, malignant bone tumor
MeSH terms: Bone Neoplasms / diagnosis, Bone Neoplasms / drug therapy, Osteomyelitis / diagnostic imaging, Osteomyelitis / drug therapy, Case Reports, Adolescent, Anti-Inflammatory Agents, Non-Steroidal / therapeutic use, Chronic Disease, Female, Humans, Radiography, Recurrence, Anti-Inflammatory Agents, Non-Steroidal, Chronic recurrent multifocal osteomyelitis

Chronic recurrent multifocal osteomyelitis (CRMO) is an unusual form of non-microbial chronic osteomyelitis. It is an exclusion diagnosis that can only be considered after ruling out infectious osteomyelitis and bone tumors. We report the case of a 13-year-old girl who was admitted for a painful swelling of the left thigh. Biological examinations did not find an inflammatory syndrome. X-rays and Magnetic Resonance Imaging were very suggestive of malignant bone tumor. But the biopsy disclosed a nonspecific osteomyelitis. Considering the strong suspicion of a malignant origin, a second biopsy was performed and confirmed the diagnosis of osteomyelitis. During the hospital stay, the patient developed a second location in the left humerus. Thus, the diagnosis of CRMO was retained. The patient was treated by NSAIDs with good clinical and radiological outcomes. This case report reminds the diagnostic challenge of this pathology that can mimic malignant tumor.
Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline
Authors: Lamia Oudrhiri, Soumiya Chiheb, Farida Marnissi, Soumaya Zamiati, Hakima Benchikhi
Journal: Pan Afr Med J (2012)
Keywords: melkersson-rosenthal syndrome, miescher's cheilitis granulomatosa, treatment
MeSH terms: Betamethasone / therapeutic use, Doxycycline / therapeutic use, Melkersson-Rosenthal Syndrome / drug therapy, Case Reports, Betamethasone / administration & dosage, Dapsone / therapeutic use, Doxycycline / administration & dosage, Drug Therapy, Combination, Female, Follow-Up Studies, Glucocorticoids / administration & dosage, Glucocorticoids / therapeutic use, Humans, Injections, Intralesional, Melkersson-Rosenthal Syndrome / diagnosis, Melkersson-Rosenthal Syndrome / pathology, Treatment Outcome, Young Adult, Glucocorticoids, Dapsone, Betamethasone, Doxycycline

We report a case of a 19-year-old girl who presented with 5-year history of swelling of upper lip and fissured tongue treated with dapsone then oral steroids without any improvement. Clinical examination found peripheral facial nerve paralysis and Labial mucosa biopsy showed non-necrotizing giganto-epithelioid granuloma. Diagnosis of Melkersson-Rosenthal syndrome was retaind because of association of cheilitis, lingua plicata and facial paralysis. Given the failure of dapsone and oral steroid we suggested an association of betamethasone injection and doxycycline. Gradual and permanent reduction of the upper lip volume was observed. One year follow up objectified no reactivation of cheilitis.
Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome-positive acute myeloid leukemia: A case report
Authors: Si-Man Huang, Tao Tao, Chao-Ling Wan, Tian-Mei Wu, Han-Yu Cao, Yan Qiu, Xiang-Dong Shen, Bin-Ru Wang, Shuai-Shuai Ge, Yan-Yan Li, Tong-Tong Zhang, Bing Wu, Sheng-Li Xue
Journal: Clin Case Rep (2023)
Keywords: philadelphia chromosome‐positive acute myeloid leukemia, flumatinib, regimen, venetoclax
MeSH terms: Case Reports

Philadelphia chromosome-positive acute myeloid leukemia (Ph + AML) is a rare type of AML with a low survival rate and poor prognosis. We first report a Ph + AML patient who remained in long-term remission after the combination of flumatinib and venetoclax, which could provide corresponding treatment ideas for clinical practice.
Oesophageal perforation following transoesophageal echocardiography: A case report on successful conservative management
Authors: Nadiah Binti Rosly, Guo Hou Loo, Mohamad Aznan Bin Shuhaili, Reynu Rajan, Nik Ritza Kosai
Journal: Int J Surg Case Rep (2019)
Keywords: cardiopulmonary bypass, cervical oesophagus, oesophageal injury, tee

Introduction:
Transoesophageal echocardiography (TOE) is a widely used intraoperative diagnostic tool in cardiac patients, and it is considered as a safe and non-invasive procedure. However, it has its known complications, which is estimated to be 0.18% with mortality reported as 0.0098%. Complications of TOE include odynophagia, upper gastrointestinal haemorrhage, endotracheal tube malpositioning and dental injury. One of the rarer complications includes oesophageal perforation, whose incidence is reported to be 0.01%.
Case presentation:
We present a case of a 61-year-old lady with mitral valve prolapse (MVP) who underwent TOE with subsequent presentation of odynophagia with left neck swelling. An upper endoscopy examination was inconclusive; however, a contrasted computed tomography of the neck showed evidence of cervical oesophageal perforation. She was managed conservatively and discharged well.
Discussion:
The trauma caused by TOE probe insertion and manipulation accounts for most of the upper gastrointestinal complications. Mortality of patients associated with oesophageal perforation can be up to 20% and doubled if the treatment is delayed for more than 24 h. Mechanism of injury from TOE probe is likely multifactorial. Predisposing factors that increase the risk of tissue disruption include the presence of unknown structural pathology. Imaging studies and an upper endoscopy examination may aid in the diagnosis of oesophageal perforation.
Conclusion:
A high index of suspicion, coupled with a tailored, multidisciplinary approach, is essential to achieve the best possible outcome. Conservative management may be worthwhile in a stable patient despite delayed presentation. Although TOE is considered a safe procedure, physicians should be made aware of such a dreaded complication.
Refractory Hypotension after Liver Allograft Reperfusion: A Case of Dynamic Left Ventricular Outflow Tract Obstruction
Authors: Michael Essandoh, Andrew Joseph Otey, Adam Dalia, Elisabeth Dewhirst, Andrew Springer, Mitchell Henry
Journal: Front Med (Lausanne) (2016)
Keywords: dynamic left ventricular outflow tract obstruction, mitral regurgitation, paradoxical hypotension, postreperfusion syndrome, systolic anterior motion of the mitral valve, transesophageal echocardiography
MeSH terms: Case Reports

Hypotension after reperfusion is a common occurrence during liver transplantation following the systemic release of cold, hyperkalemic, and acidic contents of the liver allograft. Moreover, the release of vasoactive metabolites such as inflammatory cytokines and free radicals from the liver and mesentery, compounded by the hepatic uptake of blood, may also cause a decrement in systemic perfusion pressures. Thus, the postreperfusion syndrome (PRS) can materialize if hypotension and fibrinolysis occur concomitantly within 5 min of reperfusion. Treatment of the PRS may require the administration of inotropes, vasopressors, and intravenous fluids to maintain hemodynamic stability. However, the occurrence of the PRS and its treatment with inotropes and calcium chloride may lead to dynamic left ventricular outflow tract obstruction (DLVOTO) precipitating refractory hypotension. Expedient diagnosis of DLVOTO with transesophageal echocardiography is extremely vital in order to avoid potential cardiovascular collapse during this critical period.
Case report: Visual snow as the presenting symptom in multiple evanescent white dot syndrome. Two case reports and literature review
Authors: Chenyue Hang, Yan Yan
Journal: Front Neurol (2022)
Keywords: chorioretinitis, chromatopsia, multiple evanescent white dot syndrome (mewds), visual snow, yellow-tinged vision
MeSH terms: Case Reports

Purpose:
Multiple evanescent white dot syndrome (MEWDS) usually manifests as photopsia, enlarged blind spots, scotomas, and blurred vision, which can be classified into positive and negative visual phenomena. Visual snow and chromatopsia were rarely reported in these patients. Herein, we described two Chinese female patients with MEWDS who initially presented with visual snow, and one of them also had yellow-tinged vision.
Methods:
First, we performed the chart review of two patients. Second, we reviewed the English literature for all cases of MEWDS through PubMed until December 2021, using the terms "MEWDS" or "multiple evanescent white dot syndrome." We concluded on all the reported patients' demographic features and symptoms. The visual acuity of patients with/without positive or negative visual phenomena was compared through one-way ANOVA.
Results:
Patient 1: A 27-year-old Chinese woman experienced continuous visual snow and yellow-tinged vision in the right eye for a week. She noticed tiny white and black dots involving the entire visual field and shimmering light inferiorly. Patient 2: A 22-year-old Chinese woman complained of a gray area with continuous visual snow in the temporal visual field of the left eye for 5 days. The ocular examinations, including fundus autofluorescence (FAF), optical coherence tomography (OCT), and indocyanine green angiography (ICGA), confirmed the diagnosis of MEWDS. Their symptoms resolved spontaneously without treatment. We found 60 MEWDS case reports (147 cases) in PubMed. The mean age was 31.2 years old. The mean LogMAR best-corrected visual acuity was 0.35 ± 0.39 at the first visit and 0.01 ± 0.16 at the last visit. The most common symptoms included blurred vision (72.8%), enlarged blind spot (42.2%), photopsia (37.4%), and scotoma (33.3%). We found the patients with only positive visual phenomena had significantly worse visual acuity at the first and last visit than patients with only negative visual phenomena (p = 0.008) or the patients with both positive and negative visual phenomena (p = 0.026). Four cases similar to visual snow were discovered. Compared to the MEWDS patients without visual snow, the patients with visual snow tend to have a larger proportion of females (p = 0.005) and a better visual acuity at the first visit (p = 0.007).
Conclusion:
Herein, we expand upon the clinical manifestations of MEWDS with visual snow, and the symptoms attributable to visual snow could precede the onset of MEWDS. Neurologists and ophthalmologists should carefully rule out occult chorioretinopathy before diagnosing visual snow syndrome.
Reversible Nephropathy Associated with Jet Fuel Exposure
Authors: Latif A Salam, Khabbab Amin, Regina Cheng, Noriyuki Murakami, Clinton Brown, Lawrence Kwon
Journal: Case Rep Nephrol (2020)
MeSH terms: Case Reports

Acute kidney injury (AKI) with progression to oliguric or anuric acute renal failure (ARF) is often related to use of well-known nephrotoxic agents including medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), angiotensin-converting enzyme inhibitors (ACEis)/angiotensin II receptor blockers (ARBs), and certain classes of antibiotics. Hyperosmolar IV contrast is also a well-known nephrotoxic agent. Severe sepsis with subsequent hypotension, marked hyperglycemia, and those with difficulty accessing water or with poor oral intake can also present with acute kidney injury related to kidney hypoperfusion, dehydration, and volume depletion. In this case report, we discover and discuss the possible effects of regular and daily occupational exposure of jet fuel (a mixture of hydrocarbons) on renal function. Jet fuel is an underdescribed and not well-known nephrotoxic agent; however, its direct toxicity on kidney function appears to be reversible with removal of exposure and aggressive fluid hydration.
Combining Acute Kidney Injury with Gastrointestinal Pathology: A Clue to Acute Oxalate Nephropathy
Authors: Benjamin Fox, Nishkarsh Saxena, Leah Schuppener, Laura Maursetter
Journal: Case Rep Nephrol (2018)
MeSH terms: Case Reports

Acute oxalate nephropathy (AON) is an increasingly recognized cause of acute kidney injury (AKI). Herein, we present two cases of biopsy-proven acute oxalate nephropathy in patients with gastrointestinal malabsorption, coincidentally both stemming from cholangiocarcinoma. The first is a 73-year-old male who presented with syncope and was found to have severe, oliguric AKI in the setting of newly diagnosed, nonresectable cholangiocarcinoma. The second is a 64-year-old man with remote resection of cholangiocarcinoma who presented after routine laboratory monitoring showed significant AKI. Temporary dialysis was required in both cases before renal recovery occurred. Together, these cases should increase physicians' suspicion of AON in the presence of malabsorption. By doing so, the workup of oxalate nephropathy can be expedited with prompt initiation of treatment.