OpenMed/multicare-articles huggingface dataset:
Urethral Steinstrasse following Laser Lithotripsy of Prostatic Urethral Calculi
Authors: Jennifer Den, Preston S Kerr, Tamer J Dafashy, Christopher D Kosarek, Robyn L Roberts, J Nicholas Sreshta
Journal: Case Rep Urol (2018)
MeSH terms: Case Reports

Symptomatic prostatic calculi are rare occurrences with several management options, the most popular of which is currently transurethral laser lithotripsy. This is a generally well-tolerated procedure with minimal complications. To date, no reported episodes of steinstrasse at the urethral level following prostatic calculi lithotripsy have been documented to our knowledge. We report a unique case of acute urinary retention secondary to obstructive calculi fragments following a transurethral laser lithotripsy of large prostatic calculi, further complicated by stricture at the fossa navicularis.
Multiple cystic swelling: Initial presentation of multiple myeloma
Authors: Sunil Kumar, A P Jain, Swati Waghmare
Journal: Indian J Med Paediatr Oncol (2010)
Keywords: cystic swelling, multiple myeloma, plasmacytoma
MeSH terms: Case Reports

Multiple myeloma, a disease allied to malignancy of reticuloendothelial cells, is not an uncommon condition. However, the diagnosis is often made quite late because the disease has multiple modes of presentation. We are reporting a case of multiple myeloma in a 55-year-old male who presented with multiple cystic swellings on the chest.
Two Patient Cases Illustrating the Importance of Addressing Physical and Mental Trauma as a Cause of Pain in Refugee Women
Authors: Gunilla Brodda Jansen
Journal: Front Sociol (2020)
Keywords: mental health, pain, refugee women, rehabilitation, torture
MeSH terms: Case Reports

Refugees, and more so women than men, are often seeking medical care for a wide range of health-related problems, among which persistent pain has long been recognized as a defining feature. When treating refugee women for any condition, pain and its consequences need to be addressed in the rehabilitation efforts. It is therefore essential that health professionals engaged in the care of refugee women are familiar with the physiology of pain mechanisms, including the biopsychosocial model of pain, as well as the best evidence-based practice in managing pain, acute as well as chronic. Persistent or chronic pain not only causes disability and restricted functioning but also produces psychological impairments, compounding the impact on overall personal and social functioning. Yet, the research literature on health regarding refugees is predominantly targeted at mental health problems without specific reference to pain and pain as a significant cause of distress and disability due to migration (pre-and post). Pain as a consequence of torture is also an issue that is under-assessed when refugees are seeking medical aid for pain-related problems. When aiming at treating refugee women with disabling pain, one can use the same intervention methods that are being used for other chronic pain states. Professionals need, however, to be able to work with less written information and in close co-operation with interpreters. Reviews of the rehabilitation literature have noted a lack of scientifically rigorous studies of multicomponent interventions for refugees. Only few studies have evaluated outcomes of pain management, and the quality of the evidence they provide is very low. The small number of randomized controlled trials and the resulting paucity of information means that recommendations amounting to good clinical practice for refugee women with persistent pain are lacking. The aim of this article, illustrated by two patient cases, is to point out important areas that need to be addressed within the health care system in order to improve health care for refugee women. Pain is a common reason for refugee women to seek medical aid, is a costly burden for the society, and decreases quality of life for these women.
Necrotic ulcerated and bleeding striae distensae following bevacizumab in a palliative setting for gliobastomatosis cerebri
Authors: Olivia Laugier, Laetitia Padovani, Arnauld Verschuur, Caroline Gaudy-Marqueste, Nicolas André
Journal: Ecancermedicalscience (2017)
Keywords: bevacizumab, glioblastoma, palliative care, skin lesions, steroids
MeSH terms: Case Reports

Glioblastoma cerebri is a rare paediatric malignancy with dismal prognosis [Chappé C, Riffaud L, and Tréguier C et al (2013) Primary gliomatosis cerebri involving gray matter in pediatrics: a distinct entity? A multicenter study of 14 casesChilds Nerv Syst29 565-571 https://doi.org/10.1007/s00381-012-2016-1 PMID: 23306961] and no established standard of care. Here, we report a case of ulcerated and bleeding striae distensae in a teenage girl following palliative treatment with bevacizumab and steroids.
Fatal Asphyxia Potentially Caused by COVID-19-Induced Exacerbation of Pre-existing Tracheal Stenosis
Authors: Masaatsu Kuwahara, Hiroko Otagaki, Hideaki Imanaka
Journal: Cureus (2023)
Keywords: asphyxia, covid-19, cricothyrotomy, intubation, tracheal stenosis
MeSH terms: Case Reports

We report a case of cardiac arrest due to asphyxia caused by coronavirus disease 2019 (COVID-19) in a patient with no history of tracheal intubation but with a history of subglottic stenosis. A 54-year-old man suffered a cardiac arrest at home. The patient had tracheal stenosis; therefore, it was difficult to intubate. The patient had COVID-19, which was presumed to have aggravated the existing tracheal stenosis and caused asphyxiation. The patient died seven days later. This is, to our knowledge, the first report of a patient with subglottic stenosis potentially aggravated by COVID-19, resulting in asphyxia-related cardiopulmonary arrest. The patient could not be saved, but emergency physicians should be aware that airway obstruction can be caused by viral infections, including severe acute respiratory syndrome coronavirus 2 infections. Physicians should consider the difficulty in performing oral intubation and cricothyrotomy and be aware of alternative methods to secure the airway.
Anaphylaxis following a transvaginal ultrasound
Authors: Baruch D Jakubovic, Corey Saperia, Gordon L Sussman
Journal: Allergy Asthma Clin Immunol (2016)
Keywords: anaphylaxis, iatrogenic reaction, polyethylene glycol
MeSH terms: Case Reports

Polyethylene glycol is a ubiquitous, water-soluble, organic compound found in a wide variety of commercially available products. While generally a benign substance, in rare instances, it can induce hypersensitivity reactions. Herein, we describe a case of anaphylaxis to polyethylene glycol-containing lubricating gel used for a transvaginal ultrasound. This case highlights the importance of early recognition of a rare cause of anaphylaxis that may occur in the health-care setting. It is of particular importance given the widespread use of similar lubricating materials in multiple practice settings for the use of internal examinations and ultrasonography.
Transient Complete Unilateral Oculomotor Nerve Palsy following Clipping of Ruptured Anterior Communicating Artery Aneurysm: An Abstruse Phenomenon
Authors: Joe M Das, Rashmi Sapkota, Manish Mishra
Journal: Case Rep Vasc Med (2019)
MeSH terms: Case Reports

Background:
Aneurysmal subarachnoid hemorrhage may be associated with different cranial nerve palsies, with oculomotor nerve palsy (ONP) being the most common. ONP is especially associated with posterior communicating artery aneurysms, due to the anatomical proximity of the nerve to the aneurysmal wall. Anterior communicating artery (Acom) aneurysms are very unlikely to produce ONP due to the widely separated anatomical locations of Acom and oculomotor nerve.
Case description:
Here we describe the case of a 60-year-old nondiabetic lady who presented with Acom aneurysmal subarachnoid hemorrhage having a World Federation of Neurosurgical Societies (WFNS) grade I. She underwent an uneventful right pterional craniotomy and clipping of the aneurysm, except for a short period of controlled rupture of the aneurysm. Postoperatively she developed complete ONP on the right side, though her sensorium was preserved. Computed Tomogram and Magnetic Resonance Imaging scans of the brain did not yield any useful information regarding its etiology. She was conservatively managed and kept on regular follow-up. She had a gradual recovery of ONP in the following order: pupillary reaction, ocular movements, and finally ptosis. On postoperative day 61, she had complete recovery from ONP.
Conclusion:
We describe a very unusual case of complete ONP following Acom aneurysm clipping and its management by masterly inactivity.
What role can unmanned aerial vehicles play in emergency response in the Arctic: A case study from Canada
Authors: Dylan G Clark, James D Ford, Taha Tabish
Journal: PLoS One (2018)
MeSH terms: Air Ambulances, Climate Change, Emergency Medical Services / methods, Weather, Clinical Trial, Research Support, Non-U.S. Gov't, Arctic Regions, Canada, Female, Humans, Male, Middle Aged

This paper examines search and rescue and backcountry medical response constraints in the Canadian Arctic and potential for unmanned aerial vehicles (UAV) to aid in response and preparedness. Semi-structured interviews (n = 18) were conducted with search and rescue responders, Elders, and emergency management officials to collect data on current emergency response and potential for UAV use. UAV test flights (n = 17) were undertaken with community members. We analyzed five years of weather data to examine UAV flight suitability. Numerous challenges face Arctic search and rescue and backcountry emergency response. Changing social and environmental conditions were described as increasing vulnerability to backcountry emergencies. Responders desired additional first aid and emergency training. Legal and weather restrictions were found to limit where, when and who could fly UAVs. UAVs were demonstrated to have potential benefits for hazard monitoring but not for SAR or medical response due to legal restrictions, weather margins, and local capacity. We find that communities are ill-prepared for ongoing SAR demands, let alone a larger disaster. There are numerous limitations to the use of consumer UAVs by Arctic communities. Prevention of backcountry medical emergencies, building resilience to disasters, and first responder training should be prioritized over introducing UAVs to the response system.
Near misdiagnosis of acute HIV-infection with ELISA-Western Blot scheme: Time for mindset change
Authors: Carlos Eduardo Medina-De la Garza, María de Los Ángeles Castro-Corona, Mario César Salinas-Carmona
Journal: IDCases (2021)
Keywords: acute hiv infection, elisa-western blot, hiv-diagnosis counseling, hiv-discordant results, hiv-misdiagnosis, point of care hiv-testing
MeSH terms: Case Reports

Some HIV-infection diagnostic guidelines and health care providers still rely on the ELISA-Western blot diagnostic algorithm. We present a near misdiagnosis case with discordant test results and a lack of proper counseling. We point out the need for an assertive update of health care providers on diagnostic HIV-tests.
Addressing the Horizontal Gender Division of Labor: A Case Study of Support and Obstacles in a Heavy Industry Plant in Iceland
Authors: Gudbjörg Linda Rafnsdóttir, Jill Weigt
Journal: Sex Roles (2019)
Keywords: gender equality, gender segregation, professional role, stereotyped behavior, workplace intervention, workplace policy

In the present article, we analyze a project in a heavy industry plant in Iceland in which the management aims to hire an equal number of women and men and, thereby, to work against the gender segregation of work. For their efforts, called the 50/50 strategy, the plant has received national and international awards. Observations and semi-structured interviews were conducted during five visits to the plant, including 85 interviews with 72 individuals, 49 women and 23 men. We found extensive support for the policy. The managers saw business opportunities in it, but although the employees supported the policy because it was seen as fair and modern, they doubted that achieving equal gender representation would be possible. The main emphasis so far has been on designing work organization and equipment, advertising the policy, presenting job opportunities to women outside the plant, and encouraging both genders to acquire the "right" education. Why the 50/50 target has not been reached lies partly in gender stereotypes outside the plant. Furthermore, our findings suggest that the next steps should be to challenge an alleged male working-culture within the plant. If they fail to do so, their efforts to eliminate horizontal gender segregation are unlikely to succeed and may even become counterproductive.
Serum anti-p53 antibody as a tumour marker for colorectal cancer screening
Authors: Masaya Iwamuro, Yoshinari Kawai, Tomoko Matsumoto, Masashi Uda, Hiroyuki Okada
Journal: Ecancermedicalscience (2015)
Keywords: anti-p53 antibody, cancer screening tests, colon cancers, colorectal carcinoma, early diagnosis of cancer
MeSH terms: Case Reports

A 60-year-old Japanese man presented to our hospital for further investigation of an elevated serum anti-p53 antibody level. He was diagnosed with colon cancer and the tumour was surgically resected. Histological diagnosis of advanced colon cancer without lymph node involvement or distant metastasis was made. It was noteworthy that both serum carcinoembryonic antigen (CEA) and a fecal occult blood test that were performed preoperatively were non-diagnostic. This case highlights the potential usefulness of serum anti-p53 antibody tests for detection of colorectal cancers. Moreover, sequential changes in the anti-p53 antibody levels after curative resection were observed.
Cicatricial keratoconjunctivitis associated with lichen planus
Authors: Susan Huang, Prabjot Channa
Journal: GMS Ophthalmol Cases (2015)
Keywords: cicatricial keratoconjunctivitis, cyclosporine, keratitis, lichen planus
MeSH terms: Case Reports

Purpose:
To describe a case of cicatricial keratoconjunctivitis associated with lichen planus.
Methods:
Case report.
Results:
To our knowledge, this is the sixth reported case of cicatricial keratoconjunctivitis associated with lichen planus. A 73-year-old woman had persistent cicatricial keratoconjunctivitis. Histopathologic studies of the buccal mucosa biopsy specimen revealed lichen planus.
Conclusion:
Lichen planus is a possible cause of cicatricial keratoconjunctivitis. Topical cyclosporine may stabilize the ocular surface, and additional systemic immunosuppression may be needed in severe cases. A correct diagnosis through biopsy is essential to start aggressive anti-inflammatory treatment to avoid vision loss.
Intracoronary Hydatid Cyst Resulted in Coronary Artery Disease in a Young Patient
Authors: Unsal Vural, Ahmet Arif Aglar, İlyas Kayacioglu
Journal: Braz J Cardiovasc Surg (2019)
MeSH terms: Coronary Artery Disease / parasitology, Echinococcosis / complications, Case Reports, Coronary Artery Disease / diagnostic imaging, Coronary Artery Disease / surgery, Echinococcosis / diagnostic imaging, Echinococcosis / surgery, Echocardiography, Humans, Male, Medical Illustration, Young Adult

Among all cystic echinococcosis cases, only 0.5%-2% exhibit a cardiac involvement. Only 10% of these become symptomatic. Considering the long time interval between the start of infestation and symptoms to occur, it is hard to diagnose cystic echinococcosis. When detected, even if it is asymptomatic, intramyocardial hydatid cyst requires surgical intervention due to risks of spontaneous rupture and anaphylaxis. In literature, no case of hydatid cyst located in the coronary arterial wall has been reported. Twenty-two-year-old male patient with previous history of pulmonary cystic echinococcosis was referred to us with typical symptoms of coronary artery disease. Coronary cineangiography revealed proximal left diagonal artery (LAD) occlusion. Pre-operative transthoracic echocardiography of the patient planned to undergo coronary artery bypass grafting unveiled an intracoronary calcified cystic mass. In operation, the calcified cystic mass with well-defined borders and size of 2x2 cm located within wall of proximal segment of the LAD artery was excised and double bypass with left internal thoracic artery (LITA) and great saphenous vein grafts to the LAD and first diagonal arteries, respectively, was done. Pathological analysis of the mass revealed it to be an inactive calcified hydatid cyst. Echinococcal IgG-ELISA test was positive. 12-week oral albendazole treatment (2x400 mg/day) was launched postoperatively and the patient was discharged on 7th postoperative day.
Treatment of Extensively Comminuted Mandibular Fracture with the Aid of a Condylar Positioning Device
Authors: Abd Jabar Nazimi, Tengku Ezulia, Jothi Raamahlingam Rajaran, Siti Salmiah Mohd Yunus, Syed Nabil
Journal: Case Rep Dent (2017)
MeSH terms: Case Reports

We describe a case of extensively comminuted mandibular fracture that extends bilaterally to the angle of mandible successfully treated with the use of condylar positioning device (CPD). This simple, yet effective, technique that almost exclusively described in orthognathic surgery is useful when advance surgical techniques such as pre- or intraoperative landmark identification may not be readily available. CPD technique optimizes the manual manipulations of the comminuted distal segments during fracture reduction and internal fixation. At the same time, it allows greater control of the proximal segments to avoid further surgical complication.
Pretibial Full Thickness Skin Burn following Indirect Contact from Bone-Cement Use in a Giant Cell Tumour
Authors: Buchi Rajendra Babu Arumilli, Ashok Samuel Paul
Journal: Sarcoma (2007)
MeSH terms: Case Reports

Bone cement reaches significant temperatures and is known to cause thermal and chemical damage to various tissues. All the reports of such damage occurred following a direct contact of the tissue or structure with cement. We report the case of a patient with a giant cell tumour of the proximal tibia who underwent curettage and bone cement application through a posterior approach and subsequently developed full thickness pretibial skin damage despite showing no evidence of any direct contact of the involved skin with bone cement. This is the first report of its kind and though anecdotal is a serious complication that surgeons should be aware of.
Case report: Revealing a special and rare autoimmune GFAP astrocytopathy in the spinal cord succeeding Neurobrucellosis infection
Authors: Qiang He, Junxian Liu, Zehua Zhu, Yongxiang Tang, Lili Long, Kai Hu
Journal: Front Immunol (2022)
Keywords: fdg pet, gfap astrocytopathy, case report, glial fibrillary acidic protein, neurobrucellosis
MeSH terms: Brucellosis / diagnosis, Brucellosis / drug therapy, Brucellosis / pathology, Fluorodeoxyglucose F18, Case Reports, Research Support, Non-U.S. Gov't, Astrocytes, Glial Fibrillary Acidic Protein, Humans, Spinal Cord / diagnostic imaging, Glial Fibrillary Acidic Protein, Fluorodeoxyglucose F18

Brucellosis, a zoonosis, can cause an inflammatory response in most organs and continues to be a public health problem in some endemic areas, whereas neurobrucellosis is a morbid form of brucellosis that affects the central nervous system (CNS) with poor prognosis. Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an autoimmune disease, and there have been no reports of a Brucella infection, leading to GFAP astrocytopathy. We report the case of a patient with a positive and high level of GFAP antibodies in the cerebrospinal fluid (CSF), following a Brucella infection. Although this patient did not show any responsible lesions in the diffusion sequence of the magnetic resonant imaging (MRI) scan, we found an evidence of thoracolumbar (T12) involvement on fluorodeoxyglucose (FDG) positron emission tomography (PET). The symptoms of spinal cord involvement were only partly relieved after initial treatment [doxycycline (0.1 g Bid) and rifampicin (0.6 g Qd) for 6 weeks]; however, they markedly improved after the subsequent immunosuppressive therapy [intravenous methylprednisolone (1,000 mg for 3 days)], followed by a 50% reduction from the preceding dose after 3 days, and subsequently, oral prednisone tablets (60 mg/day) was started, which was then gradually tapered [reduced to 10 mg/day every 1-2 weeks)]. The positive response to immunosuppressive therapy and treatment outcome strongly indicated the presence of an autoimmune neurological disease probably triggered by some infectious factors. Therefore, our findings reveal that a Brucella infection is one of the causes of autoimmune GFAP astrocytopathy, and when this infection is difficult to be identified by regular MRI, FDG PET can be used as a supplementary method for diagnosis and treatment.
Adult phenotype and further phenotypic variability in SRD5A3-CDG
Authors: Bülent Kara, Özgecan Ayhan, Gülden Gökçay, Nurdan Başboğaoğlu, Aslıhan Tolun
Journal: BMC Med Genet (2014)
MeSH terms: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase / genetics, Congenital Disorders of Glycosylation / enzymology, Congenital Disorders of Glycosylation / genetics, Membrane Proteins / genetics, Phenotype, Case Reports, Research Support, Non-U.S. Gov't, Adult, Congenital Disorders of Glycosylation / pathology, Congenital Disorders of Glycosylation / physiopathology, Female, Humans, Male, Mutation, Polymorphism, Single Nucleotide, Siblings, Membrane Proteins, 3-Oxo-5-alpha-Steroid 4-Dehydrogenase, SRD5A3 protein, human

Background:
SRD5A3 is responsible for SRD5A3-CDG, a type of congenital disorder of glycosylation, and mutations have been reported in 15 children. All the mutations are recessive and truncating.
Case presentation:
We present 2 brothers at the age of 38 and 40 years with an initial diagnosis of cerebellar ataxia. We found the candidate disease loci via linkage analysis using data from single nucleotide polymorphism genome scans and homozygous truncating mutation SRD5A3 p.W19X, which was previously reported in 3 unrelated children, by exome sequencing.Clinical investigations included physical and ocular examinations and blood tests. Severe ocular involvement with retinal bone spicule pigmentation and optic atrophy are the most prominent disabling clinical features of the disease. The serum transferrin isoelectric focusing (TIEF) pattern is abnormal in the patient investigated.
Conclusion:
Our patients are older, with later onset and milder clinical phenotypes than all patients with SRD5A3-CDG reported so far. They also have atypical ocular findings and variable phenotypes. Our findings widen the spectrum of phenotypes resulting from SRD5A3 mutations and the clinical variability of SRD5A3-CDG, and suggest screening for SRD5A3 mutations in new patients with at least a few of the clinical symptoms of SRD5A3-CDG.