OpenMed/multicare-articles huggingface dataset:
Inlay-retained fixed dental prosthesis: a clinical option using monolithic zirconia
Authors: Davide Augusti, Gabriele Augusti, Andrea Borgonovo, Massimo Amato, Dino Re
Journal: Case Rep Dent (2014)

DIFFERENT INDIRECT RESTORATIONS TO REPLACE A SINGLE MISSING TOOTH IN THE POSTERIOR REGION ARE AVAILABLE IN DENTISTRY: traditional full-coverage fixed dental prostheses (FDPs), implant-supported crowns (ISC), and inlay-retained FDPs (IRFDP). Resin bonded FDPs represent a minimally invasive procedure; preexisting fillings can minimize tooth structure removal and give retention to the IRFDP, transforming it into an ultraconservative option. New high strength zirconia ceramics, with their stiffness and high mechanical properties, could be considered a right choice for an IRFDP rehabilitation. The case report presented describes an IRFDP treatment using a CAD/CAM monolithic zirconia IRFDP; clinical and laboratory steps are illustrated, according to the most recent scientific protocols. Adhesive procedures are focused on the Y-TZP and tooth substrate conditioning methods. Nice esthetic and functional integration of indirect restoration at two-year follow-up confirmed the success of this conservative approach.
Short bowel syndrome as an unusual complication of strangulated congenital diaphragmatic hernia: Case report
Authors: Reema AlSadhan, Abdulaziz K Alaraifi, Magdy Abdulatif
Journal: Int J Surg Case Rep (2020)
Keywords: congenital diaphragmatic hernia, recurrent congenital diaphragmatic hernia, short bowel syndrome, strangulated congenital diaphragmatic hernia
MeSH terms: Case Reports

Introduction:
Strangulation is a rare complication of congenital diaphragmatic hernia (CDH). There are few cases in the literature describing strangulated CDH. However, none of them was a recurrence of a previously repaired defect nor resulted in short bowel syndrome.
Presentation of case:
We report an unusual case of newborn presenting with CDH that was repaired shortly after birth but developed recurrence with strangulation few months after, requiring a massive resection, resulting in short bowel syndrome (SBS). It was managed via total parenteral nutrition feeding for three months until the patient was able to tolerate orally.
Discussion:
There were one familiar case in the reported literature by Woolley of an infant developing bowel infraction as a result of CDH where he later developed short bowel syndrome.
Conclusion:
Short bowel syndrome is an unlikely outcome of strangulated CDH. Early repair of the defect should be promoted to avoid the devastating consequences of an CDH similar to the ones encountered in our case. High index of suspicion should be kept during the follow-up of patients with CDH post repair to detect early signs of recurrences.
A Rare Case of Acinar Cell Cystadenoma in a 14-Year-Old Adolescent: A Case Report
Authors: Natalie Cosgrove, Joan DiPalma, Douglas Katz, Thomas Kowalski
Journal: Case Rep Pancreat Cancer (2016)
Keywords: acinar cell cystadenoma, pancreas, pancreatic cyst
MeSH terms: Case Reports

Background: Acinar cell cystadenoma is a rare pancreatic cyst that has been described in several case reports. This lesion may be incidental or asymptomatic, occurs predominately in females, and has a mean age of onset in the fourth decade. Case Presentation: A previously healthy 14-year-old male presented with abdominal pain. He was found to have a pancreatic cystic lesion on ultrasound and cross-sectional imaging. His diagnosis remained uncertain despite additional analysis, including endoscopic ultrasound with fine-needle aspiration. The patient underwent successful laparoscopic excision for definitive diagnosis and management with an unremarkable postoperative course. He was diagnosed with a multilocular acinar cell cystadenoma. Conclusion: Acinar cell cystadenoma is a rare pancreatic cyst whose true malignant potential is unknown. Although there are no formal recommendations for post-operative monitoring and the true risk of recurrence is unknown, we recommended every other year magnetic resonance imaging/magnetic resonance cholangiopancreatography for postresection surveillance for this patient due to the theoretical risk of recurrence with malignant transformation.
Extensive pyomyositis of vastus muscles
Authors: Chong Yau Ong, Jin Lee Lim, Lourdes Ducusin Galang
Journal: Pan Afr Med J (2017)
Keywords: pyomyositis, abscess, staphylococcus aureus, thigh
MeSH terms: Pyomyositis / diagnosis, Quadriceps Muscle / pathology, Staphylococcal Infections / diagnosis, Staphylococcus aureus / isolation & purification, Case Reports, Anti-Bacterial Agents / administration & dosage, Drainage / methods, Hospitalization, Humans, Length of Stay, Male, Middle Aged, Pyomyositis / microbiology, Quadriceps Muscle / microbiology, Staphylococcal Infections / complications, Staphylococcal Infections / pathology, Thigh, Anti-Bacterial Agents

We report a case study on a patient who presented with low back and thigh pain of one month duration. He was eventually diagnosed with left thigh pyomyositis. Tissue from thigh grew Staphylococcus aureus. With commencement of antibiotics and surgical drainage, patient made recovery despite prolonged hospital stay. The underlying mechanism of the extensive abscess accompanied by lack of systemic symptoms; is related to relative immunocompromised state of having underlying diabetes mellitus.
Pediatric Multiple High-Powered Magnetic Buckyballs Ingestion-Experience From Six Tertiary Medical Centers
Authors: Guojian Ding, Hongzhen Liu, Peng Zhou, Qiong Niu, Wei Wang, Zhiqiang Feng, Shisong Zhang, Zhengmao Zhang, Lei Geng, Zhaoyun Bu, Tingliang Fu
Journal: Front Public Health (2022)
Keywords: buckyballs, acute abdomen, children, foreign body ingestion, high-powered magnet
MeSH terms: Fullerenes, Child, Eating, Hospitals, Humans, Magnetic Phenomena, Retrospective Studies, Fullerenes

Multiple high-powered magnetic Buckyball ingestions may lead to a high risk of severe complications. Great concerns have been raised by public health workers, and it remains challenging for clinicians to solve this troublesome problem. We report a large case series of children with Buckyball ingestion from six tertiary medical centers. The clinical data, including demographics, medical history, diagnosis tools, management options, intraoperative or endoscopic findings, and outcomes, were retrospectively analyzed. Seventy-one children aged 1-13 years ingested 2-41 Buckyballs. Among them, Buckyballs passed spontaneously on 2-10 days post-ingestion in seven cases; gastroscopic removal was performed in 14 cases; laparoscopic removal in 13 cases; laparoscopic-assisted surgical removal in 6 cases; and open surgical removal in 31 cases. Surgical indications included small bowel obstruction, perforation, peritonitis, acute abdominal pain, or along with ingestion of other metallic foreign bodies. Among those who underwent a surgical procedure, primary intestinal repair was performed in 44 cases, enterectomy with primary anastomosis in 6 cases. The postoperative hospital stay ranged from 5 to 28 days. No major complications occurred. In unwitnessed cases, a vague medical history and nonspecific symptoms usually make the diagnosis difficult. The treatment options should include the watch-and-wait approach, endoscopic, laparoscopic-assisted, or open surgical removal of Buckyballs, with primary intestinal repair or anastomosis. Preventive measures, including children's not having access to Buckyballs, are essential to protect children from this kind of unintentional injury.
Risperidone-Associated Neuroleptic Malignant Syndrome in an Inpatient With Schizophrenia, With Successful Rechallenge and 3 Year Follow-Up
Authors: Ting-Ren Chen, Ying-Chang Chen
Journal: Front Psychiatry (2018)
Keywords: antipsychotics, hyperthermia, neuroleptic malignant syndrome, risperidone, schizophrenia
MeSH terms: Case Reports

Neuroleptic malignant syndrome (NMS) is rare but one of the most serious adverse effects of antipsychotics. Here, we report a case of risperidone-associated NMS in which a successful rechallenge of risperidone was observed with a positive follow-up. A 47-year-old female with schizophrenia was treated with risperidone 4 mg/d for 8 months in 2009 and was admitted to our hospital in 2015 owing to violent behavior under persecutory delusions. Risperidone 2 mg/d was initiated and increased to 4 mg/d 54 days later. Further, long-acting injectable (LAI) risperidone 25 mg per 2 weeks was added on hospital day 15. On hospital day 116, NMS occurred and thus we discontinued all antipsychotics including LAI risperidone, then NMS improved. We resumed LAI risperidone 25 mg per 2 weeks on hospital day 148, thus we waited for 22 days before re-starting the drug treatment. She was discharged on hospital day 371, then switched to LAI paliperidone 150 mg per 4 weeks 2 months later. At the time of a follow-up 3 years later, NMS had not reoccurred. This case reports on an unusual presentation of NMS in which no hyperthermia was observed. Furthermore, this case indicated that NMS may occur in a dose-dependent manner. In conclusion, this case reported important information for clinicians with regard to antipsychotic drug rechallenges and proper dosing of APs to avoid or reverse NMS.
Mycosis Fungoides Involving the Dorsal Tongue
Authors: Ashley E Brown, Lindsey Schmidtberger, Kathleeen Kroger, Richard R Jahan-Tigh, Sarah S Pinney
Journal: Case Rep Dermatol Med (2018)
MeSH terms: Case Reports

Mycosis fungoides (MF) is a rare cutaneous T-cell lymphoma (CTCL) which can cause significant morbidity. During the disease course, it classically will progress through three clinical stages in the skin: patch-, plaque-, and tumor-stage. The early stages exhibit various histopathological mimics that often lead to misdiagnosis. It rarely affects the oral cavity. Oral MF is historically associated with poor prognosis. We present a rare case of MF afflicting the dorsal tongue and extremities of a 72-year-old male.
Challenging Case: Robot-Assisted Laparoscopic Prostatectomy After Prior Suprapubic Open Prostatectomy
Authors: Shirin Razdan, Sanjay Razdan
Journal: J Endourol Case Rep (2018)
Keywords: bph, ralp, open prostatectomy, prostate, prostate cancer
MeSH terms: Case Reports

Introduction: Given the ubiquity of robot-assisted laparoscopic prostatectomy (RALP) for treatment of localized prostate cancer, more surgeons are encountering challenging cases, either secondary to difficult anatomy, prior abdominal surgery, or prior radiation therapy. Our case is of RALP in a patient after prior suprapubic prostatectomy. Case Presentation: A 61-year-old otherwise healthy Hispanic gentleman presented for consultation after being found to have Gleason 4 + 4 = 8 prostate cancer on transrectal ultrasound-guided biopsy by an outside provider in July 2017. He had previously undergone suprapubic simple prostatectomy for benign prostatic hyperplasia (BPH) in Nicaragua more than a decade prior. The patient underwent RALP with bilateral nerve sparing in September 2017. The surgery was challenging in that extensive lysis of adhesions had to be performed and typical dissecting planes at the bladder neck and apex were distorted, insofar as meticulous care was taken to judiciously use thermal energy and rely on blunt dissection at these critical junctures. That being said, there were no operative or postoperative complications, the patient was discharged on postoperative day 1, and at 3-month follow-up, the patient was fully continent, maintained erections adequate for sexual intercourse, and had a prostate specific antigen <0.1. Pathology report returned Gleason 3 + 3 = 6 disease with negative surgical margins. Discussion: There is only one other example in the literature of RALP being performed after prior suprapubic prostatectomy. Our large RALP case volume (>5000 patients for a single surgeon and counting) provided us with the necessary experience required for encountering atypical anatomy, and thereby contributed to our patient's effective surgical outcome, both oncologic and functional. Conclusion: RALP for treatment of prostate cancer is a safe and appropriate option in men who have previously undergone suprapubic open prostatectomy for BPH, especially in the hands of an experienced surgeon.
CASE REPORT Use of a Hydroconductive Dressing to Treat a Traumatic Avulsive Injury of the Face
Authors: Colin Jerome Perumal, Martin Robson
Journal: Eplasty (2012)

Introduction and objective:
Traumatic avulsive injuries present complex therapeutic decisions. Radical and repeated debridement of all foreign material, necrotic tissue, bacteria, and deleterious chemicals followed by control of the bacterial bioburden and wound closure has been the gold standard. However, when such injuries occur in the face, the treatment requires modification. Specialized structures, nerves, and a maximum amount of tissue must be preserved. Topical antimicrobials may lead to dessication and further injury to tissue. Therefore, alternative treatments must be considered. Recently, a hydroconductive dressing has been demonstrated to decrease edema by removing excess exudate, to remove debris and necrotic tissue, and to decrease bacteria and deleterious cytokines in wounds.
Methods:
Regular dressings were done between 1 and 3 days by dedicated personnel, using a hydroconductive dressing. Following an initial conservative debridement and reconstruction while attempting to preserve as much of the normal structure as possible, the wounds were dressed with a hydroconductive dressing.
Results:
Using only selective conservative debridement following bony reconstruction and repeated hydroconductive dressing changes, this severe injury healed with preservation of the important facial features. No further extensive surgical procedures were required. On discharge, the patient was able to function well with a reasonably good aesthetic result. She was subsequently lost to follow-up.
Conclusion:
This case report demonstrates that a hydroconductive dressing can be useful for traumatic avulsive injuries.
A huge renal cyst mimicking ascites: a case report
Authors: Omar Riyach, Mustapha Ahsaini, Karim Tazi, Mohammed Fadl Tazi, Soufiane Mellas, Jalal Eddine El Ammari, Abdelhak Khallouk, Mohammed Jamal El Fassi, Moulay Hassan Farih
Journal: BMC Res Notes (2014)
MeSH terms: Ascites / diagnosis, Kidney Diseases, Cystic / diagnosis, Case Reports, Aged, Diagnosis, Differential, Humans, Male, Sensitivity and Specificity, Tomography, X-Ray Computed / methods

Background:
Renal cysts are common in old patients, and usually remain untreated. Giant renal cyst measuring more than 15 cm in diameter and containing more than 1500 mls of serous fluid are rarely seen. We report a case of a 75-year-old man with a giant right renal cyst.
Case presentation:
A 75-year-old man presented with a five years history of suprapubic pain, abdominal distension. He had no urological symptoms. Physical examination revealed a distended abdomen with shifting dullness. Routine hematology, biochemistry, and serum tumor markers were within normal limits. Erroneously diagnosed as ascites on ultrasonographic examination. Abdominal paracentesis of supposed ascites was performed. The diagnosis of giant renal cyst was finally made by Computed tomography (CT) and patient underwent continuous percutaneous catheter drainage with negative pressure, whereby 8 liters of fluid were removed with negative cytology. Subsequent Computed tomography after 6 months revealed disparition of the cysts, and the patient remained asymptomatic.
Conclusion:
Giant renal cysts are uncommon; we conclude that the CT remains the best exam in patients evaluated for giant renal cyst. This to the best of our knowledge is the largest renal cyst in the medical literature. Studies are needed with particular attention to the factors associated with renal cyst enlargement.
Massive Localized Lymphedema Arising from Abdominal Wall: A Case Report and Review of the Literature
Authors: Teodóra Tóth, Yi-Che Chang Chien, Sándor Kollár, Ilona Kovács
Journal: Case Rep Pathol (2015)

Massive localized lymphedema (MLL) is a rare pseudosarcomatous lesion due to localized lymphatic obstruction from variable causes. It is most common on medial aspect of thigh and inguinal region. Abdominal localization is rare and may cause clinical diagnostic confusion with other malignant tumors due to its large size. We report a case of abdominal wall MLL of a 56-year-old male patient under clinical suspicion of well differentiated liposarcoma. The literature search and differential diagnosis will be addressed. In doubt cases, immunohistochemical stain or fluorescent in situ hybridization can help to separate this entity from the other mimickers.
An Inguinal Perivascular Epithelioid Cell Tumor Metastatic to the Orbit
Authors: Zofia Tynski, Way Chiang, Albert Barrett
Journal: Case Rep Pathol (2018)
MeSH terms: Case Reports

Malignant PEComas are rare mesenchymal neoplasms. These tumors harbor distinct myomelanocytic phenotype. The PEComa family of tumors includes lymphangioleiomyomatosis, angiomyolipoma, clear cell sugar tumor of the lung, and myomelanocytic tumor of the falciparum ligament/ligamentum teres. PEComas have no known normal cell counterpart. Majority of PEComas are benign and occur predominantly in the middle-age women. These tumors are commonly encountered in the uterus. Herein, we report a 20-year-old woman with a left inguinal mass metastatic to orbit, brain, lumbar spine, and skin at presentation. To our knowledge, this is the first case of metastatic PEComa to the orbit. This is the third case of primary PEComa of the inguinal area.
Gossypiboma versus Gossip-Boma
Authors: Charanjeet Singh, Mamta Gupta
Journal: Case Rep Radiol (2011)
MeSH terms: Case Reports

Gossypiboma, or a retained surgical sponge, is a rare condition, and it can occur after any surgical intervention that requires use of internal swabs. A case of an eight-year-old girl is presented, who had right minithoracotomy for ASD closure. She was finally diagnosed to have a retained surgical sponge in the right pleural cavity.
Acute bilateral ophthalmoparesis with pupilary areflexical mydriasis in miller-fisher syndrome treated with intravenous immunoglobulin
Authors: Theocharis Papanikolaou, Cath Gray, Bernard Boothman, Gerald Naylor, George Mariatos
Journal: J Ophthalmol (2010)
MeSH terms: Case Reports

Miller-Fisher syndrome (MFS) is a rare condition characterized by the classical triad of ophthalmoplegia, ataxia, and areflexia (Fisher, 1956). It is considered a variant of Guillain-Barré syndrome (GBS) with which it may overlap, or it can occur in more limited forms. We report a case of a thirty-five-year-old male who presented with a six-day history of diplopia, following a recent chest infection. On examination, he was found to have bilateral sixth nerve palsy, bilateral fourth nerve palsy, bilateral areflexical mydriasis, ataxia and total absence of reflexes. After excluding other conditions, a diagnosis of Miller-Fisher syndrome was made. The patient was administered intravenous immunoglobulin and made an uneventful recovery.
Case Report: Theory of Mind and Figurative Language in a Child With Agenesis of the Corpus Callosum
Authors: Sergio Melogno, Maria Antonietta Pinto, Teresa Gloria Scalisi, Fausto Badolato, Pasquale Parisi
Journal: Front Psychol (2021)
Keywords: agenesis of the corpus callosum, child, cognitive profile, figurative language, theory of mind
MeSH terms: Case Reports

In this case report, we studied Theory of Mind (ToM) and figurative language comprehension in a 7.2-year-old child, conventionally named RJ, with isolated and complete agenesis of the corpus callosum (ACC), a rare malformation due to the absence of the corpus callosum, the major tract connecting the two brain hemispheres. To study ToM, which is the capability to infer the other's mental states, we used the classical false belief tasks, and to study figurative language, i.e., those linguistic usages involving non-literal meanings, we used tasks assessing metaphor and idiom comprehension. RJ's intellectual level and his phonological, lexical, and grammatical abilities were all adequate. In both the ToM false belief tasks and novel sensory metaphor comprehension, RJ showed a delay of 3 years and a significant gap compared to a typically developing control group, while in idioms, his performance was at the border of average. These outcomes suggest that RJ has a specific pragmatic difficulty in all tasks where he must interpret the other's communicative intention, as in ToM tasks and novel sensory metaphor comprehension. The outcomes also open up interesting insights into the relationships between ToM and figurative language in children with isolated and complete ACC.
PAN3- PSMA2 fusion resulting from a novel t(7;13)(p14;q12) chromosome translocation in a myelodysplastic syndrome that evolved into acute myeloid leukemia
Authors: Ioannis Panagopoulos, Ludmila Gorunova, Hege Kilen Andersen, Astrid Bergrem, Anders Dahm, Kristin Andersen, Francesca Micci, Sverre Heim
Journal: Exp Hematol Oncol (2018)
Keywords: acute myeloid leukemia, chromosome translocation, myelodysplastic syndrome, pan2/pan3 complex, pan3–psma2 fusion, proteasome, rna sequencing, t(7, 13)(p14, q12)
MeSH terms: Case Reports

Background:
Acquired primary chromosomal changes in cancer are sometimes found as sole karyotypic abnormalities. They are specifically associated with particular types of neoplasia, essential in establishing the neoplasm, and they often lead to the generation of chimeric genes of pathogenetic, diagnostic, and prognostic importance. Thus, the report of new primary cancer-specific chromosomal aberrations is not only of scientific but also potentially of clinical interest, as is the detection of their gene-level consequences.
Case presentation:
RNA-sequencing was performed on a bone marrow sample from a patient with myelodysplastic syndrome (MDS). The karyotype was 46,XX,t(7;13)(p14;q12)[2]/46,XX[23]. The MDS later evolved into acute myeloid leukemia (AML) at which point the bone marrow cells also contained additional, secondary aberrations. The 7;13-translocation resulted in fusion of the gene PAN3 from 13q12 with PSMA2 from 7p14 to generate an out-of-frame PAN3-PSMA2 fusion transcript whose presence was verified by RT-PCR together with Sanger sequencing. Interphase fluorescence in situ hybridization analysis confirmed the existence of the chimeric gene.
Conclusions:
The novel t(7;13)(p14;q12)/PAN3-PSMA2 in the neoplastic bone marrow cells could affect two key protein complex: (a) the PAN2/PAN3 complex (PAN3 rearrangement) which is responsible for deadenylation, the process of removing the poly(A) tail from RNA, and (b) the proteasome (PSMA2 rearrangement) which is responsible for degradation of intracellular proteins. The patient showed a favorable response to decitabine after treatment with 5-azacitidine and conventional intensive chemotherapy had failed. Whether this might represent a consistent feature of MDS/AML with this particular gene fusion, remains unknown.