OpenMed/multicare-articles huggingface dataset:
Ultrasound findings of diffuse metastasis of gastric signet-ring-cell carcinoma to the thyroid gland
Authors: Koji Morita, Takahiko Sakamoto, Shuji Ota, Hideo Masugi, Ikumi Chikuta, Yamato Mashimo, Naoki Edo, Takuo Tokairin, Nobuhiko Seki, Toshio Ishikawa
Journal: J Med Ultrason (2001) (2017)
Keywords: color doppler ultrasonography, neoplasm metastasis, signet-ring-cell carcinoma, stomach neoplasm, thyroid gland
MeSH terms: Carcinoma, Signet Ring Cell / diagnostic imaging, Stomach Neoplasms / diagnostic imaging, Stomach Neoplasms / pathology, Thyroid Neoplasms / diagnostic imaging, Thyroid Neoplasms / secondary, Ultrasonography, Doppler, Color, Case Reports, Aged, Biopsy, Fine-Needle, Carcinoma, Signet Ring Cell / pathology, Diagnosis, Differential, Endoscopy, Gastrointestinal, Fatal Outcome, Female, Fluorodeoxyglucose F18, Humans, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals, Thyroid Neoplasms / pathology, Radiopharmaceuticals, Fluorodeoxyglucose F18

It has been shown that metastases to the thyroid from extrathyroidal malignancies occur as solitary or multiple nodules, or may involve the whole thyroid gland diffusely. However, diffuse metastasis of gastric cancer to the thyroid is extremely rare. Here, we report a case of a 74-year-old woman with diffuse infiltration of gastric adenocarcinoma (signet-ring-cell carcinoma/poorly differentiated adenocarcinoma) cells in the thyroid. The pathological diagnosis was made based on upper gastrointestinal endoscopy with biopsy and fine-needle aspiration cytology of the thyroid. An 18F-FDG PET/CT revealed multiple lesions with increased uptake, including the bilateral thyroid gland. On thyroid ultrasound examination, diffuse enlargement with internal heterogeneity and hypoechoic reticular lines was observed. On color Doppler imaging, a blood-flow signal was not detected in these hypoechoic lines. These findings were similar to those of diffuse metastases caused by other primary cancers, such as lung cancer, as reported earlier. Therefore, the presence of hypoechoic reticular lines without blood-flow signals is probably common to diffuse thyroid metastasis from any origin and an important diagnostic finding. This is the first report to show detailed ultrasound findings of diffuse gastric cancer metastasis to the thyroid gland using color Doppler.
Variant branching pattern of axillary artery: a case report
Authors: Swamy Ravindra Shantakumar, K G Mohandas Rao
Journal: Case Rep Vasc Med (2012)

During routine dissection of an approximately 50-year-old male cadaver for the undergraduate medical students at Melaka Manipal Medical College, Manipal University, Manipal, we came across a variation in branching pattern of right axillary artery. The second part of axillary artery gave rise to a common trunk which divided into the subscapular and lateral thoracic arteries. The third part of right axillary artery gave rise to anterior and posterior circumflex humeral arteries. Variations in the branching pattern of axillary artery are important for the surgeons performing interventional or diagnostic procedures in cardiovascular diseases.
Prethymic cytoplasmic CD3 negative acute lymphoblastic leukemia or acute undifferentiated leukemia: a case report
Authors: Elisa Cannizzo, Giovanni Carulli, Luigi Del Vecchio, Antonio Azzarà, Sara Galimberti, Virginia Ottaviano, Frederic Preffer, Mario Petrini
Journal: Case Rep Hematol (2011)
MeSH terms: Case Reports

Acute undiffentiated leukemia (AUL) is an acute leukemia with no more than one membrane marker of any given lineage. Blasts often express HLA-DR, CD34, and/or CD38 and may be positive for terminal deoxynucleotidyl transferase (TdT). The expression of CD34, HLA-DR, and CD38 has been shown in pro-T-ALL, although in this case, blasts should also express CD7 and cyCD3. However, some cases of T-ALL without CD3 in the cytoplasm and all TCR chain genes in germ line configuration are reported, features that fit well with a very early hematopoietic cell. We report a case of acute leukemia CD34+/-HLADR+CD7+CD38+cyCD3- in which a diagnosis of AUL was considered. However the blasts were also positive for CD99 and TCR delta gene rearrangement which was found on molecular studies. Therefore a differential diagnosis between AUL and an early cyCD3 negative T-ALL was debated.
Case Report: Respiratory paralysis associated with polymyxin B therapy
Authors: Yachan Ning, Yanqi Chu, You Wu, Ying Huang, Chunmei Wang, Li Jiang
Journal: Front Pharmacol (2022)
Keywords: colistin, neuromuscular blockage, neurotoxicity, polymyxin b, respiratory paralysis
MeSH terms: Case Reports

Polymyxin B (PMB) and colistin are bactericidal polypeptide antibiotics discovered in 1947 and 1949 for the treatment of gram-negative bacterial infections. Polymyxin was used clinically in the 1950s, but it was gradually replaced by other antibiotics in the 1980s because of its high nephrotoxicity and neurotoxicity. In recent years, the increase of multidrug-resistant negative bacteria has led to the resurgence of polymyxin use. However, its side effects are not clear. Respiratory paralysis caused by PMB-related neuromuscular blockade is a rare but potentially fatal effect. We report a case of respiratory paralysis probably caused by polymyxin B infusion.
A rare tumour in the cerebellopontine angle: endolymphatic sac tumour
Authors: Abderrahim Elktaibi, Amal Damiri, Issam Rharrassi, Mohamed Reda Elochi, Mohamed Oukabli, Ali Akhaddar, Mohamed Boucetta, Abderrahmanne Al Bouzidi
Journal: Pan Afr Med J (2018)
Keywords: endolymphatic sac, cerebellopontine angle, papillary tumor, radiotherapy, surgery
MeSH terms: Adenocarcinoma / diagnosis, Cerebellar Neoplasms / diagnosis, Cerebellopontine Angle / pathology, Ear Neoplasms / diagnosis, Case Reports, Adenocarcinoma / etiology, Adenocarcinoma / pathology, Cerebellar Neoplasms / pathology, Dizziness, Ear Neoplasms / pathology, Endolymphatic Sac / pathology, Hearing Loss / etiology, Humans, Male, Middle Aged

We present a case of a papillary tumour at the cerebellopontine angle in a 54-year-old man. He presented with right-sided ear pain associated with dizziness and hearing loss. The radiological diagnosis was in favor of acoustic neurinoma. Surgical excision was performed and the diagnosis of the endolymphatic sac tumour was made. Endolymphatic tumour is a low grade adenocarcinoma that originates from the endolymphatic sac. The definitive diagnosis requires a combination of clinical features, radiological finding and pathological correlation.
Exploiting the advantages of a wireless seed localization system that differentiates between the seeds: Breast cancer resection following neoadjuvant chemotherapy
Authors: Elizabeth Shaughnessy, Charmi Vijapura, Chantal Reyna, Jaime Lewis, Kyle Lewis, Su-Ju Lee, Lawrence Sobel, Rifat Wahab, Lauren Rosen, Ann Brown
Journal: Cancer Rep (Hoboken) (2023)
Keywords: breast localization, tagged axillary dissection, tagged lymph node, wireless localization
MeSH terms: Breast Neoplasms / drug therapy, Breast Neoplasms / surgery, Case Reports, Research Support, Non-U.S. Gov't, Adult, Female, Humans, Lymph Node Excision / methods, Lymph Nodes / pathology, Lymph Nodes / surgery, Mastectomy, Neoadjuvant Therapy

Background:
Most wireless localization methods utilize only one means of detection for the surgeon, sufficient to localize a single small breast lesion for excision. Complex cases requiring bracketing of a larger lesion or localization of two or more close lesions can superimpose the signal from separate "seeds" with such methods. The lack of discernment between the localization "seeds" can disorient the surgeon, risking a missed lesion on excision and longer operative times. with the use of neoadjuvant chemotherapy prior to breast surgery, the necessity of localizing both a breast lesion and an axillary lymph node previously biopsied is becoming frequent.
Case:
A 44 year-old woman underwent neoadjuvant chmotherapy for a breast cancer the did not express estrogen receptor, progesterone receptor, or HER2 receptor. In establishing the extent of disease, a suspicious ipsilateral lymph node was biopsied and found to contain metastatic disease. She had an excellent response to the chemotherapy, with decreased size of the primary tumor and the previously biopsied lymph node. The patient desired breast conservation. The primary tumor and associated calcifications were bracketed using two different Smartclips™, with a third localizing the lymph node biopsied.
Conclusion:
This report illustrates how the use of three SmartClips™, within the EnVisioTM system, allowed for separate tracking of each "seed" throughout a complex surgery in a patient following neoadjuvant chemotherapy. This resulted in successful resection of both the tumor and the tagged lymph node.
Pyogenic Granuloma/Peripheral Giant-Cell Granuloma Associated with Implants
Authors: Enric Jané-Salas, Rui Albuquerque, Aura Font-Muñoz, Beatríz González-Navarro, Albert Estrugo Devesa, Jose López-López
Journal: Int J Dent (2015)
MeSH terms: Review

Introduction. Pyogenic granuloma (PG) and peripheral giant-cell granuloma (PGCG) are two of the most common inflammatory lesions associated with implants; however, there is no established pathway for treatment of these conditions. This paper aims to illustrate the successful treatment of PG and PGCG and also report a systematic review of the literature regarding the various treatments proposed. Methods. To collect relevant information about previous treatments for PG and PGCG involving implants we carried out electronic searches of publications with the key words "granuloma", "oral", and "implants" from the last 15 years on the databases Pubmed, National Library of Medicine's Medline, Scielo, Scopus, and Cochrane Library. Results. From the electronic search 16 case reports were found showing excision and curettage as the main successful treatment. As no clinical trials or observational studies were identified the authors agreed to present results from a review perspective. Conclusion. This is the largest analysis of PG and PGCG associated with implants published to date. Our review would suggest that PGCG associated with implants appears to have a more aggressive nature; however the level of evidence is very limited. Further cohort studies with representative sample sizes and standard outcome measures are necessary for better understanding of these conditions.
Cutaneous Larvae Migrans Treated with a Single Dose of Ivermectin
Authors: Iris S Harrison, Kiran Lukose, Bhagwan Dass, Nila S Radhakrishnan
Journal: Case Rep Med (2022)
MeSH terms: Case Reports

Hookworm-related cutaneous larva migrans (HrCLM) is a clinical diagnosis based on a history of exposure to contaminated soil and is associated with a characteristic red serpiginous lesion that migrates within the epidermis. Our patient presented with a red, tortuous migratory rash with localized pruritus on the left plantar foot of 1-month duration. He lacked recent travel history outside the southeastern United States. Upon admission, he presented with peripheral blood eosinophilia, an uncommon feature of HrCLM. A single dose of ivermectin was sufficient for treatment, and symptoms resolved within 3 days. This case highlights the increased incidence of domestically acquired hookworm infections, explores this epidemiological shift, and emphasizes relevant differential diagnoses.
Never Too Old? Occurrence of Medulloblastoma in the Elderly beyond the 70th Year of Life
Authors: Homajoun Maslehaty, Johannes Van de Nes, Sarah Teuber-Hanselmann, Christoph Moenninghoff, Ulrich Sure, Neriman Oezkan
Journal: Case Rep Neurol Med (2018)
MeSH terms: Case Reports

The occurrence of medulloblastoma (MB) in the elderly is an absolutely rare event. Concerning this issue we report on two MB patients beyond the 70th year of life. Two patients older than 70 years presented with a mass in the posterior fossa without evidence of a preexisting malignant tumor. After careful radiological work-up the suspected diagnosis was metastasis of an unknown primary tumor. Both patients underwent surgery and histopathological analysis revealed MB in both cases (classical MB and desmoplastic type). The two cases presented here represent also one classical MB and one additional desmoplastic MB. To our knowledge we report for the first time that there are different molecular subtypes of MB in the elderly patients that seem to be consistent with those subtypes mainly occurring in young adults. Unfortunately the patients died within one week after surgery due to respiratory insufficiency and an unclear cause. The presented cases show that MB can occur in the elderly. Although this constellation is absolutely rare, MB should be considered in the differential diagnosis, especially when a primary tumor is not known or detected.
Late pulmonary embolism in a patient with non-severe COVID-19: case report, value of antithrombotic prophylaxis and literature review
Authors: Phany Brunelle Issanga Maloumbi, Ayoub Hassouni, Junior Rocyr Ibara-Onguema, Bouchra Maatof, Franck Bienvenu Ekoba-Othende, Abdelmajid Bouzerda
Journal: Pan Afr Med J (2021)
Keywords: sars-cov-2, anthithrombotic prophylaxis, case report, late pulmonary embolism, non-severe covid-19
MeSH terms: COVID-19 / complications, Pulmonary Embolism / diagnosis, Case Reports, Review, Adult, Female, Fibrinolytic Agents / administration & dosage, Humans, Pulmonary Embolism / virology, Real-Time Polymerase Chain Reaction, Serologic Tests, Severity of Illness Index, Time Factors, Fibrinolytic Agents

Since the onset of the COVID-19 pandemic, several small cohorts have reported the recurrent occurrence of venous thromboembolic disease (VTE), particulary pulmonary embolism, in serious patients hospitalized in intensive care units. We report the case of a patient who presented a minor COVID-19 infection treated on an outpatient basis with good clinical resolution. She developed a pulmonary embolism three weeks after the onset of symptoms. When she was admitted to the emergency room, the two real time reverse transcription polymerase chain reactions (RT-PCRs) performed were negative, moreover the anti-SARS-CoV-2 Immunoglobulin Gs (IgGs) serological test was positive and the chest scanner without and with injection of contrast product showed specific images of COVID-19 with intermediate pulmonary embolism according to the classification of the European society of cardiology (ESC). This observation is interesting since there are not many studies which address the question of the occurrence of late pulmonary embolism in patients with non-severe COVID-19 and raises the discussion on the criteria for the initiation of thromboembolic prophylaxis treatment at the first diagnosis of the disease and duration of that treatment.
External Beam Radiation and Brachytherapy for Prostate Cancer: Is It a Possible Trigger of Large Cell Neuroendocrine Carcinoma of the Urinary Bladder?
Authors: Ali Zakaria, Bayan Al Share, Sri Kollepara, Cynthia Vakhariya
Journal: Case Rep Oncol Med (2017)
MeSH terms: Case Reports

Neuroendocrine tumors commonly involve the respiratory and gastrointestinal systems. Primary genitourinary neuroendocrine tumors are rare, accounting for less than 1% of all bladder carcinomas. Four histopathologic subtypes have been described. Among those, large cell neuroendocrine carcinoma (LCNEC) is the least common, is more aggressive, and generally presents in an advanced stage with poor prognosis compared to transitional cell bladder carcinoma. There is no standardized treatment regimen because of the rarity of the disease. Herein, we present a case of 72-year-old male patient with previously treated prostate cancer, who received external beam radiation therapy and high dose brachytherapy, presenting with intermittent hematuria. Cystoscopy and transurethral resection of bladder tumor (TURBT) were performed. The histopathology and immunohistochemistry were consistent with large cell neuroendocrine carcinoma (LCNEC). Further studies are required to proof the higher risk of neuroendocrine carcinoma of the bladder in patients treated with external beam radiation therapy and brachytherapy for prostate cancer.
Twiddler's syndrome in spinal cord stimulation
Authors: Rafid Al-Mahfoudh, Yuen Chan, Hsu Pheen Chong, Jibril Osman Farah
Journal: Acta Neurochir (Wien) (2016)
Keywords: failed back surgery syndrome, ipg, spinal cord stimulation, twidder’s syndrome
MeSH terms: Equipment Failure, Failed Back Surgery Syndrome / therapy, Spinal Cord Stimulation / adverse effects, Case Reports, Adult, Female, Humans, Middle Aged, Syndrome

Background:
The aims are to present a case series of Twiddler's syndrome in spinal cord stimulators with analysis of the possible mechanism of this syndrome and discuss how this phenomenon can be prevented.
Method:
Data were collected retrospectively between 2007 and 2013 for all patients presenting with failure of spinal cord stimulators. The diagnostic criterion for Twiddler's syndrome is radiological evidence of twisting of wires in the presence of failure of spinal cord stimulation.
Results:
Our unit implants on average 110 spinal cord stimulators a year. Over the 5-year study period, all consecutive cases of spinal cord stimulation failure were studied. Three patients with Twiddler's syndrome were identified. Presentation ranged from 4 to 228 weeks after implantation. Imaging revealed repeated rotations and twisting of the wires of the spinal cord stimulators leading to hardware failure.
Conclusions:
To the best of our knowledge this is the first reported series of Twiddler's syndrome with implantable pulse generators (IPGs) for spinal cord stimulation. Hardware failure is not uncommon in spinal cord stimulation. Awareness and identification of Twiddler's syndrome may help prevent its occurrence and further revisions. This may be achieved by implanting the IPG in the lumbar region subcutaneously above the belt line. Psychological intervention may have a preventative role for those who are deemed at high risk of Twiddler's syndrome from initial psychological screening.
Volvulus of the ascending colon due to failure of zygosis: A case report and review of the literature
Authors: Dennis Mazingi, Chenesa Mbanje, Godfrey I Muguti, Taurai Zimunhu, Bothwell Mbuwayesango
Journal: Int J Surg Case Rep (2019)
Keywords: intestinal fixation, mesentery, mobile right colon syndrome, peritoneal zygosis, peritoneum, volvulus

Introduction:
Volvulus of the mobile ascending colon is a serious complication of a subtle embryological abnormality that frequently goes unrecognised. There has been renewed interest in the development of the mesentery because of its relevance to the contemporary management of surgical diseases. This case is presented to illustrate the dire consequences of missing this diagnosis and to review the fascinating embryology of the condition as well as its clinical implications.
Presentation of case:
We report on a 23-year-old male who presented with signs and symptoms of distal small bowel obstruction after a long prior history of intermittent right lower quadrant pain. At laparotomy, a 360-degree counter-clockwise volvulus of the entire right colon was noted as the result of an excessively long ascending mesocolon and unattached hepatic flexure. All gangrenous bowel was resected with primary ileocolic anastomosis performed thereafter. The patient did well post-operatively and was subsequently discharged.
Discussion:
Interruption of the in-utero events of fixation known as peritoneal zygosis lead to a persistence of the mesocolon in parts of the bowel that ordinarily are retroperitoneal. The events that lead to this anomaly are poorly understood and have been subject to controversy for centuries. New insights have challenged surgical dogma and informed new surgical techniques. Its true incidence is probably underestimated because of its indolent clinical prodrome, and it requires a high index of suspicion.
Conclusion:
Failure of peritoneal zygosis is implicated in a myriad of clinical conditions. Expeditious recognition and intervention in the prodromal period can avert potentially disastrous complications.
Intranasal Ectopic Tooth in Adult and Pediatric Patients: A Report of Two Cases
Authors: Isabela Polesi Bergamaschi, Bernardo Olsson, Aline Monise Sebastiani, Guilherme Dos Santos Trento, Nelson Luis Barbosa Rebellato, Leandro Eduardo Klüppel, Delson Joao da Costa, Rafaela Scariot
Journal: Case Rep Surg (2019)
MeSH terms: Case Reports

The aim of this study was to report two rare cases of ectopic tooth into the nasal cavity. The first case reports a 32-year-old female patient with the main complaint of having a tooth inside her nose. According to her, this condition causes pain and sporadic nosebleed. The patient had a facial trauma when she was 6 years old. The second case refers to an 8-year-old girl with left incomplete unilateral cleft lip and palate. The main complaint was left-sided nasal obstruction by a white hard mass. The treatment for both cases was surgical removal of the ectopic erupted tooth under general anesthesia. In conclusion, we can state that the surgical removal of intranasal tooth is a safe procedure and improves patient's quality of life.
Tricuspid valve infective endocarditis in a patient with psoas abscess complicated by septic pulmonary emboli and severe tricuspid regurgitation in Cameroon: challenges in the diagnosis and management in a resource limited setting (a case report)
Authors: Clovis Nkoke, Jerry Brown Aseneh, Emmanuel Njang, Conrald Metuge Ekukole, Kingsly Nkongho Enoh
Journal: Pan Afr Med J (2022)
Keywords: laminectomy, case report, psoas abscess, tricuspid infective endocarditis
MeSH terms: Bacteremia / complications, Endocarditis / complications, Endocarditis, Bacterial / complications, Endocarditis, Bacterial / diagnosis, Endocarditis, Bacterial / therapy, Psoas Abscess / diagnosis, Psoas Abscess / therapy, Sepsis / complications, Tricuspid Valve Insufficiency / diagnosis, Tricuspid Valve Insufficiency / therapy, Case Reports, Cameroon, Humans, Male, Middle Aged, Tricuspid Valve / diagnostic imaging

Infective endocarditis of the tricuspid valve is rare in non-intra-venous drug abusers. Few cases of psoas abscess complicated by tricuspid infective endocarditis have been reported. A 61-year-old man underwent a laminectomy. Three weeks later he developed persistent fever, abdominal pain, back pain and hip pain, weight loss, gradually and abdominal distension. Abdomino-thoracic computed tomographic scan showed a left psoas muscle abscess and cavitary pulmonary lesions suggestive of septic pulmonary emboli. Two dimensional transthoracic echocardiography showed an oscillating mass on the anterior leaflet of the tricuspid valve compatible with a vegetation. There was severe tricuspid regurgitation with right atrial and right ventricular dilatation. Secondary psoas abscess though rare is an important cause of bacteremia and there is a potential of bacteremia progressing to serious systemic infection like tricuspid endocarditis which can be fatal without prompt and appropriate treatment.
Prosthetic valve endocarditis: a complication of spinal epidural abscess
Authors: Armando Bedoya, Bethany Gentilesco
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

Epidural injections for chronic low back pain are controversial, and their effectiveness is debated. Although epidural injections are considered a minor procedure with low morbidity, catastrophic complications may occur. We describe a case of prosthetic valve endocarditis secondary to an epidural abscess after epidural injection to alert clinicians to this unusual association.