OpenMed/multicare-articles huggingface dataset:
Tachyarrhythmia improved by management of low back pain in a patient with delayed diagnosis of infective spondylodiscitis: A case report
Authors: Koshi Ota, Naoya Onishi, Kensuke Fujii, Eriko Nakamura, Yasuo Oishi, Masahiro Oka, Kanna Ota, Yohei Sano, Hiroki Yokoyama, Akira Takasu
Journal: SAGE Open Med Case Rep (2020)
Keywords: critical care/emergency medicine, anesthesia/pain, infectious diseases
MeSH terms: Case Reports

A 77-year-old man presented to the emergency room with a 1-month history of persistent low back pain with the absence of vital sign abnormalities. On several previous orthopedic surgery clinic visits, pathological back pain had not been considered and pain killers had been prescribed because he had low back pain due to lumbar spinal canal stenosis. He was admitted to the intensive care unit for infectious spondylodiscitis and infective endocarditis with disseminated abscess caused by methicillin-resistant Staphylococcus aureus. Shock refractory tachyarrhythmia could not be managed with antiarrhythmic agent in the intensive care unit. Intractable low back pain and persistent tachyarrhythmia were adequately managed by pain control with fentanyl in the intensive care unit. Infectious spondylodiscitis and infective endocarditis were effectively managed with anti-methicillin-resistant Staphylococcus aureus drugs, initially in rotational usage, but the patient died of extended-spectrum beta-lactamase-producing Escherichia coli pneumonia on day 50 of hospitalization. Infectious spondylodiscitis should have been considered for persistent low back pain with hemodialysis, fever, and a history of device implantation. Pain management may be necessary for persistent tachycardia that proves unresponsive to usual antiarrhythmic medications.
A Fatal Case of Septic Shock Secondary to Acinetobacter Bacteremia Acquired from a Platelet Transfusion
Authors: C Nevala-Plagemann, P Powers, M Mir-Kasimov, R Rose
Journal: Case Rep Med (2019)
MeSH terms: Case Reports

Background:
Transfusion of blood products is a frequent and often necessary lifesaving intervention. While changes to blood bank practices over the past several decades have reduced the infectious complications associated with transfusions, risks still exist. Septic transfusion reactions caused by bacterial contamination of blood products, especially platelets, still occur relatively frequently. Unfortunately, clinical recognition of septic transfusion reactions is difficult due to significant symptom, exam, and laboratory abnormality overlap between different types of transfusion reactions, as well as other conditions. Novel methods have been developed to detect blood product contamination but have yet to be widely implemented in the United States.
Case report:
A 67-year-old male with chronic thrombocytopenia was transfused with platelets prior to a planned procedure. Shortly afterwards, he developed fever and hypotension. He was transferred to the intensive care unit where he was treated with aggressive fluid resuscitation and broad-spectrum antibiotics. The patient went on to develop progressively worsening shock and profound disseminated intravascular coagulation. Blood cultures from the patient and the transfused platelets grew an Acinetobacter species. Despite aggressive resuscitative efforts and appropriate antibiotics, the patient died approximately 48 hours following the transfusion reaction.
Conclusion:
We report a fatal case of septic shock associated with Acinetobacter bacteremia caused by platelet transfusion. Our review of the literature revealed only one other documented platelet transfusion associated fatality caused by Acinetobacter species. Novel pathogen reduction and contamination detection methods have been developed but have yet to be widely adopted in the United States.
Obturator Nerve Injury: An Infrequent Complication of TOT Procedure
Authors: S Aydogmus, S Kelekci, H Aydogmus, E Ekmekci, Y Secil, S Ture
Journal: Case Rep Obstet Gynecol (2014)

Transvaginal mid-urethral slings have become the most preferred surgical treatment option for female stress urinary incontinence. However, various complications have been reported for these operations occurring especially during penetration of the retropubic space. It can negatively affect patient's quality of life. Early treatment increases the chance of complete normalization of the functions. In this case report we presented a case of obturator nerve damage that was diagnosed and treated at early stage after TOT operation.
Woman with Pregnancy and Lactation-Associated Osteoporosis (PLO)
Authors: Nasrin Bazgir, Elham Shafiei, Neda Hashemi, Hassan Nourmohamadi
Journal: Case Rep Obstet Gynecol (2020)
MeSH terms: Case Reports

Osteoporosis is a disease known to reduce bone density and to damage bone microarchitecture leading to increased fracture risk. Osteoporosis is one of the most common diseases among the middle aged and elderly people that impose high costs on the community. So far, despite rare cases of pregnancy and lactation-associated osteoporosis (PLO) reported in Iran, it can be treated with accurate diagnosis. Patient Introduction. A 24-year-old woman was referred to the outpatient rheumatologic clinic after the cesarean section during the first pregnancy with severe back pain. In the thoracolumbar radiographs, a loss of vertebral height in the T11 to L5 vertebra was recognized. Other complaints were abdominal pain and anemia. In order to evaluate the gastrointestinal disease and celiac, the patient underwent gastrointestinal and hematologic workup. Ultimately, secondary causes of the osteoporosis were excluded. Based on the patient's clinical course, imaging finding, and exclusion of other causes of osteoporosis, the patient was diagnosed with PLO. Conclusion. Clinicians should be aware of PLO as rare complication of pregnancy. The situation should be particularly considered in females offering from new onset back pain in the third trimester of pregnancy or breastfeeding period.
Encephalic Schistosoma japonicum resembles brainstem neoplasm: Case report and literature review
Authors: Kang Wu, Hong Yu Zhao, Kai Shu, Ting Lei, Liang Zeng
Journal: Front Neurol (2022)
Keywords: bilharzia, blood flukes, brainstem, granuloma, neuroschistosomiasis, pseudotumor
MeSH terms: Case Reports

Encephalic schistosomiasis is a rare and severe parasitic disease which manifests as granuloma formation around ectopic eggs that migrate to the brain. We present a rare case of a pseudotumoral form of Schistosoma japonicum in the brainstem that was initially misidentified as a malignant tumor. The patient presented with intermittent headaches, diplopia, and left limb weakness. Neurological examination revealed hypoesthesia of the left lower limb, limitation of right eye abduction, and decreased muscle strength of the left upper limb. The cerebrospinal fluid tested positive for antibodies against S. japonicum. After standard treatment for schistosomiasis, the patient achieved complete remission. This case highlights that encephalic schistosomiasis can occur in the brainstem and resemble a neoplasm on magnetic resonance imaging. Once diagnosed, however, complete remission is achievable by non-invasive medical treatment.
Urethral metastasis from non-seminomatous germ cell tumor: a case report
Authors: Vijay Agarwal, Tze Wah, Sameer Chilka, Johnathan Joffe, Dan Stark
Journal: J Med Case Rep (2011)

Introduction:
We present a case of nonseminomatous germ cell tumor of the testes with acute urinary retention secondary to urethral metastasis. This presentation, and similar cases of urethral metastasis from this tumor, have not been reported previously.
Case presentation:
A 35-year-old Caucasian man presented to hospital with a history of acute urinary retention. On examination he was found to have right testicular enlargement with raised β-human chorionic gonadotrophin, serum α-fetoprotein and lactate dehydrogenase levels. He underwent radical left inguinal orchidectomy and histology confirmed a nonseminomatous germ cell tumor of the testes. Cystoscopy carried out due to urinary retention showed penile metastasis and the biopsy confirmed metastatic malignant undifferentiated teratoma. Staging computed tomography scan and magnetic resonance imaging of the pelvis showed pulmonary, pelvic nodal, ischial and penile metastasis. The diagnosis of the International Germ Cell Cancer Collaborative Group of poor prognosis metastatic nonseminomatous germ cell tumor was made, following which he received four cycles of bleomycin, etoposide and cisplatin chemotherapy with curative intent. He had a complete marker and an excellent radiological response. He is currently under follow up.
Conclusion:
The unusual presentation of lymphovascular spread in this case of nonseminomatous germ cell tumor highlights the need to include routine pelvic imaging in the assessment and follow up of testicular cancer.
A Rare Case of Recurrent Mucoepidermoid Carcinoma of the Nasal Vestibule
Authors: Vladimir Bedeković, Miro Leventić, Boris Jelavić, Robert Trotić, Mihael Ries, Mirjana Kostić, Tomislav Lauc
Journal: Case Rep Oncol Med (2017)
MeSH terms: Case Reports

We report a rare case of a large recurrent mucoepidermoid carcinoma (RMEC) in an 81-year-old female smoker, which has originated in the right nasal vestibule. The recurrent tumour was inadequately treated for 6 years. It was a slow-growing tumour for 3 years and then began to enlarge at a higher pace. In the next three years it has covered a large part of the face. The patient had refused any medical treatment. The tumour caused breathing and swallowing difficulties. Because of the profuse bleeding from the tumour, the patient underwent emergency surgery. Surgical treatment consisted of rhinectomy and resection of the central upper lip and part of the right cheek. The facial defect was reconstructed immediately. Recovery from surgery was fast with no complications. Postoperative Multislice Computed Tomography scan showed no metastases so the patient did not receive any chemotherapy or radiotherapy. During a 2.5 years' follow-up period there was no recurrence of the disease.
Gallbladder volvulus: it's a small whirl
Authors: Ben Layton, Velauthan Rudralingam, Rochelle Lamb
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

An 85-year-old female with an extensive past medical history attended our accident and emergency department with vague abdominal pain and distension. Clinical examination and initial blood tests demonstrated features of sepsis and she was commenced on broad spectrum antibiotics. Following admission, a contrast-enhanced CT scan of the abdomen and pelvis was performed, which showed an unusual configuration of the gallbladder. There was significant luminal distension of the gallbladder, which was found to lie in an unusual horizontal position anterior to the liver edge. This was a new finding compared with a recent CT pulmonary angiogram that demonstrated a normal gallbladder anatomy. In addition, there was abrupt angulation of the gallbladder neck, demonstrating a "beak" sign as well as indrawing of the vascular pedicle forming a mini "swirl" sign. The constellation of gallbladder distension, abnormal lie, "beak" and mini "swirl" sign together is a strong indicator of gallbladder torsion. Coexistent right lower lobe pneumonia was noted. The patient was too frail for surgical intervention and succumbed to underlying sepsis. Post-mortem examination demonstrated a gangrenous gallbladder secondary to volvulus. We present a rare case of gallbladder volvulus and highlight CT findings to help the radiologist make a pre-operative diagnosis.
Minimal change disease in horseshoe kidney
Authors: Yosr Chaabouni, Rahma Guesmi, Yosr Hentati, Khaoula Kammoun, Mohamed Ben Hmida, Zeineb Mnif, Tahya Boudawara, Jamil Hachicha
Journal: Pan Afr Med J (2017)
Keywords: horseshoe kidney, glomerulonephritis, minimal change disease, nephritic syndrome
MeSH terms: Fused Kidney / diagnostic imaging, Glucocorticoids / administration & dosage, Nephrosis, Lipoid / diagnosis, Case Reports, Biopsy, Fused Kidney / pathology, Humans, Male, Nephrosis, Lipoid / drug therapy, Nephrosis, Lipoid / pathology, Treatment Outcome, Young Adult, Glucocorticoids

The horseshoe kidney is a frequent urological birth defect. The most frequent complications are urinary tract infections, stones and hydronephrosis. The occurrence of glomerular disease in horseshoe kidney is rare. Therefore, we report the first case of minimal change disease occurring in a patient with horseshoe kidney in literature. A 22-year-old Caucasian man without personal or family medical history admitted to the pneumology department for a pulmonary artery embolism. In presence of a generalized oedema, a biological assessment was performed yielding intense nephrotic syndrome with urine protein excretion 22g/day. The abdominal ultrasound revealed a horseshoe kidney. Hence a scanno-guided kidney biopsy was taken yielding minimal change disease. High dose steroids were started, then gradually tapered with good response. Horseshoe kidney is the most common renal fusion anomaly, with a prevalence of 0.25% among the general population. The occurrence of glomerular nephropathy in horseshoe kidney has been reported in few cases. We report the first case of minimal change disease occurring in a patient with horseshoe kidney in literature. The mechanism of the association between the horseshoe kidney and these renal pathologies could not be explained in the previous reports. There is no literature data indicating a high rate of glomerulonephritis in horseshoe kidneys. The co-incidence of two renal diseases in this patient can be only a coincidence. The question that arises is whether this glomerulopathy is associated or not with this anatomical abnormality. Further studies are needed to answer this question.
Unusually High Levels of CA19-9 Associated with Mature Cystic Teratoma of the Ovary
Authors: Monika Madaan, Manju Puri, Ritu Sharma, Harvinder Kaur, Shubha Sagar Trivedi
Journal: Case Rep Obstet Gynecol (2014)

Introduction. Mature cystic teratoma is the benign tumor of the ovary. CA19-9 levels, although a marker of pancreatic malignancy, have been found to be raised in large ovarian mature cystic teratomas. Case Report. We report a case of a young female who had unusually high levels of CA19-9 in the blood associated with large ovarian mature cystic teratoma. The levels returned to normal 12 weeks after cystectomy was performed. Conclusion. This case highlights the fact that although raised tumor marker may be associated with a benign pathology thorough evaluation to rule out malignancy still must be done.
Persistent Hemarthrosis of the Knee after Arthroscopic Meniscal Repair
Authors: Shunichiro Kambara, Shinichi Yoshiya, Shintaro Onishi, Ryoji Yasumizu, Toshiya Tachibana
Journal: Case Rep Orthop (2023)
MeSH terms: Case Reports

Introduction:
In this case report, we report a patient with complicated with persistent hemarthrosis following arthroscopic meniscal repair. Case Presentation. A 41-year-old male patient presented with persistent swelling of the knee 6 months after arthroscopic meniscal repair and partial meniscectomy performed for lateral discoid meniscal tear. The initial surgery was performed at another hospital. Four months after the surgery, swelling of the knee was noted when he resumed running. At his initial visit to our hospital, intra-articular blood accumulation was revealed via joint aspiration. A second arthroscopic examination performed 7 months after the initial procedure showed healing of the meniscal repair site and synovial proliferation. The suture materials identified during the arthroscopy were removed. Histological examination of the resected synovial tissue showed inflammatory cell infiltration and neovascularization. In addition, a multinucleated giant cell was identified in the superficial layer. After the second arthroscopic surgery, the hemarthrosis did not recur, and the patient was able to resume running without symptom one and a half years post-surgery.
Conclusion:
Bleeding from the proliferated synovia at or near the periphery of the lateral meniscus was thought to be the cause of the hemarthrosis as a rare complication following arthroscopic meniscal repair.
Successful Use of Ertapenem for the Treatment of Enterobacter cloacae Complex Infection of the Central Nervous System (CNS)
Authors: Sunish Shah, Dayna McManus, Jeffrey E Topal
Journal: Case Rep Infect Dis (2019)
MeSH terms: Case Reports

A 55-year-old female with a past medical history of cocaine use and hypertension was admitted for intracranial hemorrhage requiring right decompressive craniotomy with duraplasty. Due to persistent fevers, a head CT scan obtained on day 28 of hospitalization identified a low-density subgaleal fluid collection overlying the duraplasty. Aspiration of this collection was sent for culture which grew 2+ Enterobacter cloacae complex susceptible to sulfamethoxazole-trimethoprim (SMX-TMP), gentamicin, ciprofloxacin, and ertapenem. Based on these results, the patient was transitioned from empiric vancomycin and ceftazidime to SMX-TMP and metronidazole. Despite treatment with SMX-TMP and metronidazole, aspirated subgaleal collection cultures remained positive for E. cloacae. Intrathecal gentamicin was therefore added; however, repeat subgaleal culture collections remained persistently positive. Given the persistently positive subgaleal culture collections, the patient was transitioned from SMX-TMP and metronidazole to ertapenem. After transition to ertapenem, subgaleal cultures were sterilized and the patient's infection was resolved. This report suggests ertapenem may be a viable option for central nervous system infections; however, further study is needed.
Temporal bone osteoblastoma involving temporomandibular joint diagnosed as simple disc disorders: A case report
Authors: Feiya Zhao, Xinyue Zhang, Qiaoting Pan, Xin Ye, Mengfei Yu, Zhiyong Li, Huiming Wang
Journal: Front Surg (2023)
Keywords: ossifying fibroma, osteoblastoma, osteoid osteoma, osteosarcoma, temporomandibular joint, temporomandibular joint disorder
MeSH terms: Case Reports

Background:
Osteoblastoma is quite rare in the oromaxillo-facial region, while the mandible is always the predilection. However, in our case, the lesion was located in the left temporal articular tubercle, involving the adjacent skull base, which is extremely rare in the literature.
Case reports:
It had been diagnosed as the most common temporomandibular joint disorder in the local hospital before the patient came to our department, mainly due to the primary symptom, that was, the patient got pain in the left temporomandibular joint area while opening the mouth. However, we found a mass of bone lesions at the left temporal articular tubercle in MRI and cone beam CT, and it turned out to be an osteoblastoma after surgery. The patient's primary symptom disappeared after recovering from the surgery, and there have been no indications of complication or recurrence up to now.
Conclusion:
Osteoblastoma is very rare in the temporomandibular joint region. It could easily miss the possibility of a benign tumor due to its unusual location and confusing chief complaint in this case. Our report provides experience in the identification of osteoblastoma in rare sites.
Case Report: Gene Heterogeneity in the Recurrent and Metastatic Lesions of a Myxoid Chondrosarcoma Patient With Aggressive Transformation
Authors: Xuanhong He, Yitian Wang, Chang Zou, Chuanxi Zheng, Yi Luo, Yong Zhou, Chongqi Tu
Journal: Front Genet (2022)
Keywords: nr4a3, extraskeletal myxoid chondrosarcoma, genetic heterogeneity, recurrent and metastatic tumor, treatment
MeSH terms: Case Reports

Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma. In view of the indolent course throughout the prolonged natural history of EMC, it was considered as a low-grade soft-tissue sarcoma. However, recent studies have revealed a high recurrence and metastatic potential in EMC, and the invasiveness of EMC may progress during the protracted clinical course. The mechanism for this aggressive transformation remains unknown. Here, we present a rare case of EMC with aggressive behavior. This case was confirmed via pathology and NR4A3 fluorescent in situ hybridization. To verify the genetic characteristics of this rare case, a total gene sequencing analyses was performed in the recurrent and metastatic lesions. Intriguingly, different gene mutations were determined in the recurrent and metastatic lesions, which implied the genetic heterogeneity among the different lesions might be related to the aggressiveness of EMC. Furthermore, we discuss a few potential agents against the mutated genes in this case, which may provide novel insights regarding the targeted therapy of EMC.
Right upper lobe pulmonary sequestration masquerading clinically and radiologically as malignancy: a case report
Authors: Ankit Gupta, Gavin Chetty, David Hopkinson, Jagan Rao, Govind Chetty
Journal: J Surg Case Rep (2023)
MeSH terms: Case Reports

Bronchopulmonary sequestration is a rare disease in which a non-functional region of pulmonary tissue receives an aberrant vascular supply and lacks normal communication with the tracheobronchial tree. We present the case of a 30-year-old female with a primary complaint of unexplained weight loss and no other additional signs or symptoms. In view of this, computed tomography imaging was ordered, showing a 33HU mass in the right upper lobe. A specialist radiologist reviewed the images and concluded that the most likely differentials were mediastinal lymphoma or thymic malignancy. Video-assisted thoracoscopic surgery was performed, when it was seen that no malignancy was present, but rather a bronchopulmonary sequestration. Histology confirmed the diagnosis; the patient fared well post-operatively. Bronchopulmonary sequestration is a rare pathology, with most cases occurring in the lower lung lobes. This case is highly atypical, due to the lack of clinical features and the lesion radiologically mimicking the appearance of malignancy.
Case Report: Durable response to immuno-chemotherapy in a case of ROS1 fusion-positive advanced lung adenocarcinoma: A case report
Authors: Ningning Yan, Siyuan Huang, Linlin Li, Qianqian Guo, Di Geng, Huixian Zhang, Sanxing Guo, Xingya Li
Journal: Front Pharmacol (2022)
Keywords: nsclc, ros1, chemo-immunotherapy, immune checkpoint inhibitor, lung adenocarcinoma
MeSH terms: Case Reports

Immune checkpoint inhibitors (ICIs) have greatly transformed the treatment and improved the prognosis for patients with non-small cell lung cancer (NSCLC) without driver gene alterations. However, the effects of ICI combination therapy in ROS1 fusion-positive NSCLC remains unclear. Herein, we present a case with ROS1 fusion-positive NSCLC treated with ICI plus chemotherapy. The patient achieved a continuous partial response (PR) to ICI plus chemotherapy and a more than 35 months progression free survival. This case demonstrates that ICI plus chemotherapy is a promising option for patients with ROS1 fusion-positive NSCLC.