OpenMed/multicare-articles huggingface dataset:
Biofilm on ventriculo-peritoneal shunt tubing as a cause of treatment failure in coccidioidal meningitis
Authors: Larry E Davis, Guy Cook, J William Costerton
Journal: Emerg Infect Dis (2002)
MeSH terms: Biofilms / growth & development, Equipment Contamination, Meningitis, Fungal / drug therapy, Meningitis, Fungal / microbiology, Ventriculoperitoneal Shunt / adverse effects, Case Reports, Research Support, U.S. Gov't, Non-P.H.S., Antifungal Agents / therapeutic use, Coccidioides / isolation & purification, Coccidioidomycosis / drug therapy, Coccidioidomycosis / microbiology, Fluconazole / therapeutic use, Humans, Male, Middle Aged, Treatment Failure, Antifungal Agents, Fluconazole

We describe a case of recurrent coccidioidal meningitis in which a fungal biofilm on the tip of ventriculo-peritoneal shunt tubing was likely responsible for a 4-year persistence of Coccidioides immitis, despite the patient's taking an adequate dosage of fluconazole. Fungal biofilms should be considered as a cause for treatment failure and fungal persistence, especially when artificial prostheses or indwelling catheters are present.
Congenital Giant Dysplastic Kidney Presenting as Respiratory Distress: A Case Report
Authors: Mahesh Kumar, Geeta Gathwala, K N Ratttan, Sandeep Lather, Poonam Dalal
Journal: J Neonatal Surg (2017)
Keywords: dysplastic kidney, giant, newborn, respiratory distress
MeSH terms: Case Reports

Multicystic dysplastic kidney (MCDK) is the most common form of renal cystic disease in children and is one of the most common causes of abdominal mass in infancy. Here in we are reporting a rare case of a large MCKD that caused respiratory compromise and the infant presented with respiratory distress.
Thrombolysis in Children: A Case Report and Review of the Literature
Authors: Gary M Woods, Dennis W Kim, Matthew L Paden, Heather K Viamonte
Journal: Front Pediatr (2022)
Keywords: covid-19, may-thurner, paget-schroetter, extracorporeal life support (ecls), pediatrics, thrombolysis, thrombosis
MeSH terms: Review

Thromboembolism (TE), including venous thromboembolism (VTE), arterial TE, arterial ischemic stroke (AIS), and myocardial infarction (MI), is considered a relatively rare complication in the pediatric population. Yet, the incidence is rising, especially in hospitalized children. The vast majority of pediatric TE occurs in the setting of at least one identifiable risk factor. Most recently, acute COVID-19 and multisystem inflammatory syndrome in children (MIS-C) have demonstrated an increased risk for TE development. The mainstay for the management pediatric TE has been anticoagulation. Thrombolytic therapy is employed more frequently in adult patients with ample data supporting its use. The data for thrombolysis in pediatric patients is more limited, but the utilization of this therapy is becoming more commonplace in tertiary care pediatric hospitals. Understanding the data on thrombolysis use in pediatric TE and the involved risks is critical before initiating one of these therapies. In this paper, we present the case of an adolescent male with acute fulminant myocarditis and cardiogenic shock likely secondary to MIS-C requiring extracorporeal life support (ECLS) who developed an extensive thrombus burden that was successfully resolved utilizing four simultaneous catheter-directed thrombolysis (CDT) infusions in addition to a review of the literature on the use of thrombolytic therapy in children.
Complete lung collapse in a young adolescent
Authors: T H Ahmed, A Esmail, G Calligaro, K Dheda
Journal: Afr J Thorac Crit Care Med (2018)
Keywords: atypical carcinoid, bronchial, carcinoid, neuroendocrine tumor, typical carcinoid
MeSH terms: Case Reports

Bronchial carcinoid tumours (BCTs) arise from the neuroendocrine cells of the bronchial epithelium known as Kulchitsky cells. They represent ~25% of all carcinoid tumours, usually have a central distribution, and present with features of bronchial obstruction. They are the most common lung malignancy in children. Here we report the case of a 14-year-old girlwith chronic respiratory symptoms and left lung collapse due to bronchial carcinoid. The differential diagnosis of segmental, lobar or total lung collapse in a young person also includes mucus plugging or foreign body aspiration.
Preservation and Tissue Handling Technique on Iatrogenic Dural Tear with Herniated Nerve Root at Cauda Equina Level
Authors: Ahmad Jabir Rahyussalim, Yoshi Pratama Djaja, Ifran Saleh, Ahmad Yanuar Safri, Tri Kurniawati
Journal: Case Rep Orthop (2016)
MeSH terms: Case Reports

Iatrogenic or incidental dural tear is a relatively common complication in lumbar decompression surgery. Although mostly there are no changes that occurred in long-term result following an incidental durotomy, the sequelae are not always benign especially when the herniated nerve root is involved. Preservation and tissue handling is paramount in order to prevent further injury. Two cases of dural tear with herniated nerve root complicating the lumbar decompression surgery are presented. Direct watertight repair was performed using the preservation and tissue handling concept. Assessing the relative size between the dural tear and the root mass is the key in determining whether enlargement of tear is needed. Whenever feasible, the tear will not be enlarged. Opening the vent by using a suture anchor and manually repositioning the nerve root with a fine instrument is the key for an atraumatic handling of the herniated nerve root. Clinical and neurophysiology examination was performed postoperatively and no further neurologic deficit occurred despite the iatrogenic injury. Although some debate on a few intraoperative and postoperative details still persists, tissue handling and preservation concept should be applied in all cases.
Acquired uterine arteriovenous malformation following dilation and curettage: a case report
Authors: Andela Manisha, Amardeep Tembhare
Journal: Pan Afr Med J (2022)
Keywords: uterine arteriovenous malformation, case report, dilatation and curettage, power doppler, uterine artery embolization
MeSH terms: Arteriovenous Malformations, Case Reports, Adult, Curettage, Dilatation, Female, Humans, Pregnancy, Uterine Hemorrhage, Uterus, Young Adult

Arteriovenous malformation of the uterus is a rare encounter with sporadic incidence. They are usually acquired following events like dilation and curettage or abortions. It should always be considered as a diagnostic possibility in women presenting with torrential vaginal bleeding. We report a case of 24-years-old woman presenting with excessive bleeding following dilation and curettage. She was diagnosed with an acquired uterine arteriovenous malformation after conducting Doppler angiography. She was meticulously managed by performing uterine artery embolization. Embolization technique for uterine arteriovenous malformation (AVM) is generally used in fewer crisis circumstances as well as in emergency situations. Management by selective arterial embolization reduces the morbidity of surgery and hospital stay.
Idiopathic Scrotal Calcinosis: A Case Report and Review of Postoperative Outcomes
Authors: Mathew Yamoah Kyei, Robert Djagbletey, Afua Darkwa Abrahams, James Edward Mensah
Journal: Case Rep Urol (2020)
MeSH terms: Case Reports

Idiopathic scrotal calcinosis is a rare condition, characterized by the idiopathic deposition of calcium in the scrotal dermis leading to the formation of a single nodule or multiple nodules of different sizes. Surgical excision of the nodules reduces symptoms and improves cosmesis. We present a case of idiopathic scrotal calcinosis that had an en bloc excision of scrotal skin nodules and primary closure of the scrotal skin. Handling each hemiscrotum as a separate entity and preserving the median raphe with its uninvolved skin improved the cosmesis. Reported outcomes of surgery were satisfactory with no postoperative complications. At 30 months of follow-up, the residual scrotal skin had regained its laxity and the scrotum its normal configuration. There is the risk of recurrence of the calcific nodules post excision, but these may be smaller in size and with regained scrotal configuration that could be amenable to excision with further preservation of the native scrotal skin.
Point-of-care ultrasound of the diaphragm in a liver transplant patient with acute respiratory failure
Authors: Federico Barbariol, Luigi Vetrugno, Livia Pompei, Adelisa De Flaviis, Giorgio Della Rocca
Journal: Crit Ultrasound J (2015)
Keywords: acute respiratory failure, anesthesia, diaphragm dysfunction, intensive care, liver transplantation, point-of-care, ultrasonography

In some intensive care, nowadays, ultrasound diagnostics have become an extension of the physical examination (like a stethoscope). In this report, we discuss the case of an acute respiratory failure which arose immediately after the end of general anesthesia. An initial bedside ultrasound evaluation applying the 'BLUE protocol' showed no pathological changes capable of explaining the clinical picture; however, by evaluating also the right and left hemidiaphragms, we made a diagnosis of diaphragmatic dysfunction, which would probably have been difficult to diagnose without the aid of the diaphragm ultrasound. We therefore decided to avoid intubation, transfer the patient to the intensive care unit, and treat him conservatively with non-invasive ventilation only. To our knowledge, this is the first case report that has shown the usefulness of ultrasonography in detecting diaphragmatic dysfunction as a cause of acute respiratory failure with a subsequent change in patient management. The use of bedside ultrasonography provides practical functional information on the diaphragmatic function in patients with acute respiratory failure and can also be easily repeated if follow-up is required. This feature is still held in little consideration, but it can affect the diagnosis and the treatment of critically ill patients.
Sonographic Features of a Tuberculous Cold Abscess: A Case Report and Literature Review
Authors: Amir Alzarrad, Salman Naeem, Serena Rovida
Journal: POCUS J (2023)
Keywords: point of care ultrasound(pocus), coldabscess, extrapulmonarytuberculosis, osteomyelitis, ultrasound
MeSH terms: Case Reports

The use of point of care ultrasound (POCUS) to aid diagnosis of tuberculosis has been investigated in countries where concomitant endemic prevalence of HIV increases the incidence of extrapulmonary tuberculosis (EPTB). In such cases, using a focused assessment with sonography for HIV-associated tuberculosis (FASH) scan has found to be immensely advantageous as a rapid diagnostic tool in low resource settings where other imaging modalities are scarce. The prevalence of EPTB in immunocompetent patients in industrialised countries is growing. Since EPTB can manifest itself in almost any part of the human body, symptomatic patients present with constitutional and non-specific symptoms. In our case, a 44-year-old male presented to the emergency department (ED) with a 3-month history of left-sided chest pain and swelling of the chest wall. Clinical examination revealed a swollen and tender lump above the left first rib. Palpation of the thoracic (T7) vertebral body demonstrated localised pain. POCUS showed a collection of heterogenous material with fluid content and specks of hyperechoic 'ring-like' structures. Further investigations led to the diagnosis of EPTB. The patient was admitted and treated for EPTB where he went on to make a full recovery. This case report highlights the role of integrating POCUS in clinical examination of patients with suspected EPTB, which can expedite its diagnosis and management.
Primary adrenal leiomyosarcoma: a case report and literature review
Authors: Mencoboni M, Bergaglio M, Truini M, Varaldo M
Journal: Clin Med Oncol (2008)
MeSH terms: Case Reports

The case presented here illustrates a 75 year old female patient who underwent surgical resection of a right adrenal mass of uncertain nature. The final histological diagnosis was consistent with leiomyosarcoma arising from the adrenal anatomic site.PRIMARY LEIOMYOSARCOMA OF THE ADRENAL GLAND IS A VERY RARE MALIGNANT MESENCHYMAL NEOPLASM: to our knowledge, this is only the twelfth case reported in literature.We describe the clinical course and a brief review of clinical and histological features, biologic behaviour, diagnostic approaches and therapeutic strategies.
Chlamydophila abortus pelvic inflammatory disease
Authors: Gernot Walder, Herwig Meusburger, Helmut Hotzel, Albrecht Oehme, Walter Neunteufel, Manfred P Dierich, Reinhard Würzner
Journal: Emerg Infect Dis (2003)
MeSH terms: Anti-Bacterial Agents / therapeutic use, Chlamydophila / growth & development, Chlamydophila Infections / microbiology, Doxycycline / therapeutic use, Pelvic Inflammatory Disease / microbiology, Case Reports, Adult, Antibodies, Bacterial / blood, Chlamydophila / genetics, Chlamydophila Infections / diet therapy, DNA, Bacterial / chemistry, DNA, Bacterial / genetics, Enzyme-Linked Immunosorbent Assay, Female, Humans, Polymerase Chain Reaction, Sequence Analysis, DNA, Anti-Bacterial Agents, Antibodies, Bacterial, DNA, Bacterial, Doxycycline

We report the first documented case of an extragestational infection with Chlamydophila abortus in humans. The pathogen was identified in a patient with severe pelvic inflammatory disease (PID) by sequence analysis of the ompA gene. Our findings raise the possibility that Chlamydiaceae other than Chlamydia trachomatis are involved in PID.
Orbital Metastasis of Breast Cancer Mimicking Invasive Fungal Rhinosinusitis
Authors: Mayara Tabai, Igor Moreira Hazboun, Emerson Taro Inoue Sakuma, Marcelo Hamilton Sampaio, Eulalia Sakano
Journal: Case Rep Otolaryngol (2016)

Introduction. A range of traumatic, vascular, inflammatory, infectious, and neoplastic processes can affect the orbit and its structures. In the area of otolaryngology, the rhino-orbital-cerebral involvement of invasive fungal rhinosinusitis can affect the orbit, which may look like initially a rhinosinusitis or even mimic malignancy. Case Presentation. Female patient, 32 years old, with headache and ocular proptosis. She was using prednisone in immunosuppressive doses for a year and had breast cancer treated three years earlier. The initial CT scan showed opacification of the sphenoid and ethmoid sinuses, left intraorbital involvement and contrast impregnation in the cavernous sinus. The biopsy resulted positive for invasive ductal carcinoma of the breast. Discussion. The initial CT scan of our patient showed both signs of early changes of invasive fungal rhinosinusitis (IFR) and possible metastatic involvement. The intracranial extension and ocular involvement are usually the most common signs of IFR (first hypothesis). Among metastases at the orbit and the eye, breast and lung carcinomas are the most frequent. Conclusion. Although several studies on the differential diagnosis of orbital lesions exist, especially when it concerns the involvement of the nasal cavity, the diagnosis by imaging is still a challenge.
Hemoperitoneum after Ovulation in Systemic Lupus Erythematosus and Autoimmune Thrombocytopenia
Authors: Cara Buskmiller, Henri Rosenberg, Sandeep Sen
Journal: Case Rep Obstet Gynecol (2019)
MeSH terms: Case Reports

Background:
Three prior cases of hemoperitoneum associated with immune thrombocytopenia (ITP) have been reported in adolescents. This reports a case of hemoperitoneum after ovulation in an adult.
Case:
A 34-year-old nulligravida presented with abdominal pain after a heavy period and rebound tenderness. Urine beta-hCG was negative, hemoglobin was 5.4, and platelet count was zero. CT revealed hemoperitoneum and contrast blush surrounding the left ovary. She was treated for newly diagnosed systemic lupus erythematosus and steroid-refractory ITP. Her platelet count and symptoms improved.
Conclusion:
Hemoperitoneum after ovulation in ITP is rare; this represents the first adult case in the literature and reviews differential diagnosis of thrombocytopenia. The obstetrician/gynecologist is part of a multidisciplinary team caring for patients with bleeding of gynecological origin and should withhold surgical intervention for hemoperitoneum when medical therapy is warranted.
Focal retrograde amnesia: voxel-based morphometry findings in a case without MRI lesions
Authors: Bernhard Sehm, Stefan Frisch, Angelika Thöne-Otto, Annette Horstmann, Arno Villringer, Hellmuth Obrig
Journal: PLoS One (2011)
MeSH terms: Amnesia, Retrograde / diagnosis, Functional Neuroimaging, Magnetic Resonance Imaging, Case Reports, Research Support, Non-U.S. Gov't, Amnesia, Retrograde / complications, Amnesia, Retrograde / physiopathology, Brain / physiopathology, Case-Control Studies, Epilepsy / complications, Humans, Male, Neuropsychological Tests, Young Adult

Focal retrograde amnesia (FRA) is a rare neurocognitive disorder presenting with an isolated loss of retrograde memory. In the absence of detectable brain lesions, a differentiation of FRA from psychogenic causes is difficult. Here we report a case study of persisting FRA after an epileptic seizure. A thorough neuropsychological assessment confirmed severe retrograde memory deficits while anterograde memory abilities were completely normal. Neurological and psychiatric examination were unremarkable and high-resolution MRI showed no neuroradiologically apparent lesion. However, voxel-based morphometry (VBM)-comparing the MRI to an education-, age-and sex-matched control group (n = 20) disclosed distinct gray matter decreases in left temporopolar cortex and a region between right posterior parahippocampal and lingual cortex. Although the results of VBM-based comparisons between a single case and a healthy control group are generally susceptible to differences unrelated to the specific symptoms of the case, we believe that our data suggest a causal role of the cortical areas detected since the retrograde memory deficit is the preeminent neuropsychological difference between patient and controls. This was paralleled by grey matter differences in central nodes of the retrograde memory network. We therefore suggest that these subtle alterations represent structural correlates of the focal retrograde amnesia in our patient. Beyond the implications for the diagnosis and etiology of FRA, our results advocate the use of VBM in conditions that do not show abnormalities in clinical radiological assessment, but show distinct neuropsychological deficits.
The use of interleukin-23 inhibitors to treat immune-related psoriasis induced by immune checkpoint inhibitors and in patients with active cancer: A case series and review of the literature
Authors: Cynthia Fournier, Marcus Otho Butler, Maxwell Benjamin Sauder
Journal: SAGE Open Med Case Rep (2023)
Keywords: cancer, dermatology, dermatoses, immune-related adverse events, immunology, immunotherapy, inflammatory, melanoma, psoriasis
MeSH terms: Case Reports

Immune checkpoint inhibitors have revolutionized cancer treatment but can induce immune-related adverse events including psoriasis. Managing immune-related psoriasis or psoriasis in a cancer setting is challenging with a lack of safety data. We describe three patients receiving interleukin-23 inhibitors to manage psoriasis in an active cancer setting, including one with immune-related psoriasis. Interleukin-23 inhibitors were effective for all patients. While being on interleukin-23 inhibitors, one patient had cancer partial response, one had deep partial response but then progressed and died from her melanoma, and one suffered melanoma progression.
Reporting a Case of Solid Pseudopapillary Neoplasm of the Pancreas in a 44-Year-Old Woman with Parallel Analysis of Literature
Authors: Sargun Singh, Qing Zhao, Teviah E Sachs, Kevan Hartshorn
Journal: Case Rep Oncol Med (2023)
MeSH terms: Case Reports

We present a distinctive case of solid pseudopapillary neoplasm as seen in a 44-year-old woman who presented with an abdominal mass but unremarkable labs with no elevation in any of the tumor markers. Her symptomatology ranged from typical symptoms suggestive of malignancy such as weight loss, lethargy, and anorexia to complaints like abdominal pain and jaundice. Prior to presenting at our center, she was given no hope or much in terms of treatment options. She was found to have a substantial mass over the body and tail of pancreas with characteristic and typical gross as well as histological features. Subsequently, she underwent a successful surgery and has found herself in remission since.
Environmental Uncertainty as a Moderator of Entrepreneurship Orientation and Innovation Capability during the Pandemic: A Case of Written Batik SMEs in Yogyakarta
Authors: Humam Santosa Utomo, Susanta Susanta
Journal: F1000Res (2021)
Keywords: entrepreneurship orientation, environmental uncertainty, innovation capability, written batik
MeSH terms: COVID-19 / epidemiology, Pandemics, Case Reports, Research Support, Non-U.S. Gov't, Commerce, Data Collection, Humans, Writing

Background: Written batik is one of Indonesia's cultural heritages that must be preserved. During the Covid-19 pandemic, written batik producers in Indonesia experienced increasing challenges due to the uncertainty of the business environment. Innovation is a solution to the problems faced by SMEs during a pandemic to survive. This study aims to examine the effect of entrepreneurship orientation on innovation capability. This study also examines the role of moderating environmental uncertainty in strengthening the effect of entrepreneurship orientation on innovation capability. Methods: The research was conducted at the centre of small and medium-sized batik companies Giriloyo, Bantul, Yogyakarta, Indonesia. Respondents of this study were 130 small and medium companies selected by random sampling. The questionnaire is used as a primary data collection tool. WarpPLS has been used to analyze the effect between variables in this study. Results: Entrepreneurship orientation is an important aspect in improving the innovation capabilities of SMEs. Environmental uncertainty during the COVID-19 pandemic has strengthened the effect of entrepreneurship orientation on innovation capabilities. Conclusions: The findings of this study indicate that entrepreneurship orientation has a significant effect on innovation capabilities. Environmental uncertainty significantly strengthens the effect of entrepreneurship orientation on innovation capability.
Case Report: Hypopituitarism Presenting With Nonconvulsive Status Epilepticus
Authors: Huimin Li, Lina Xu, Fengbing Yang, Longbin Jia, Hongjiang Cheng, Wei Liu
Journal: Front Neurol (2021)
Keywords: case report, hormone, hypopituitarism, nonconvulsive status epilepticus, seizure
MeSH terms: Case Reports

Introduction: Hypopituitarism is defined as one or more partial or complete pituitary hormone deficiencies. Nonconvulsive status epilepticus (NCSE) refers to a state of continuous or repetitive seizures without convulsions. In this paper, we review a case of an old female patient with hypopituitarism who presented with NCSE, which is rare in the clinic. Case Report: This paper describes a 67-year-old female patient with hypopituitarism who presented as NCSE. She had surgical resection of pituitary tumor half a year before the seizures and did not get regular hormone replacement therapy. She presented general convulsive status epilepsy as the initial symptom and got sedation and antiepileptic drug in the emergency room. The seizure was terminated but the patient fell in coma in the following days. The patient had magnetic resonance imaging (MRI) and other inspects, and EEG showed epileptic discharges. Combining these clinical symptoms and examinations, we made the diagnosis of NCSE. Finally, she regained consciousness after the treatment with diazepam. Conclusion: This case report and literature review investigated the possible mechanism of hypopituitarism presenting with NCSE.