OpenMed/multicare-articles huggingface dataset:
Brain Abscess Associated with Polymicrobial Infection after Intraoral Laceration: A Pediatric Case Report
Authors: Fumihiro Ochi, Hisamichi Tauchi, Toyohisa Miyata, Tomozo Moritani, Toshiyuki Chisaka, Junpei Hamada, Kozo Nagai, Minenori Eguchi-Ishimae, Mariko Eguchi
Journal: Case Rep Pediatr (2020)
MeSH terms: Case Reports

Brain abscesses, infections within the brain parenchyma, can arise as complications of various conditions including infections, trauma, and surgery. However, brain abscesses due to polymicrobial organisms have rarely been reported in children. We herein report a case of a 9-year-old girl with unresolved congenital cyanotic heart disease (CCHD) presenting with right hemiplegia who was diagnosed with brain abscess caused by Streptococcus intermedius, Parvimonas micra, and Fusobacterium nucleatum after oropharyngeal injury. She was treated with intravenous antimicrobial therapy, drainage under craniotomy, and antiedema therapy with glycerol and goreisan, which led to the improvement of right hemiplegia to baseline; she was discharged following eight weeks of intravenous antimicrobial therapy. The clinical diagnosis of the brain abscess was difficult due to the nonspecific presentation, highlighting the importance of cranial imaging without haste in patients at increased risk for brain abscesses such as those with CCHD, presenting with fever in the absence of localizing symptoms or fever, accompanied with abnormal neurological findings.
Dandy-Walker Syndrome Associated with Scoliosis: Clinical Presentation, Preoperative Assessment, and Treatment
Authors: Athanasios I Tsirikos, Sarah J Wordie
Journal: Case Rep Orthop (2020)
MeSH terms: Case Reports

Dandy-Walker syndrome (DWS) affects the posterior cranial fossa resulting in characteristic dysmorphic facial and body features. Scoliosis is not typically reported as an extracranial manifestation of this condition. We present a 12-year-old female patient who developed a right thoracic scoliosis measuring 60° with increased lumbar lordosis. Scoliosis correction was indicated to alleviate back pain, improve cosmesis, and prevent respiratory complications. A multidisciplinary preoperative assessment included cardiac, respiratory, anaesthetic, and neurology reviews. She underwent a posterior spinal fusion from T2 to L3 with pedicle hook/screw and rod instrumentation and a combination of locally harvested autologous and allograft bone. This resulted in excellent deformity correction and a balanced spine in the coronal and sagittal planes. The patient made an uneventful recovery and returned gradually to her normal level of activities. She was monitored in clinic until she completed her growth (4 years after surgery); the satisfactory surgical outcome was maintained at follow-up and was associated with high patient satisfaction. Scoliosis can occur in children with DWS with resemblance to adolescent idiopathic scoliosis in regard to type of coronal deformity, age at presentation, surgical techniques, and postoperative recovery. Early identification of scoliosis in patients with DWS can allow preoperative planning and prompt surgical management in order to reduce the risk of significant morbidity which can occur if the scoliosis is allowed to deteriorate. Excellent deformity correction can be achieved and maintained beyond skeletal maturity in order to improve physical appearance, as well as preserve level of function and quality of life.
Ramsey hunt syndrome after antimonial treatment for American Cutaneous Leishmaniasis
Authors: Melissa de Sousa Melo Cavalcante, Karina López Rodríguez, José Alejandro Lazo Diéguez, Luciana Mendes Dos Santos, Maria das Graças Vale Barbosa Guerra, Jorge Augusto de Oliveira Guerra
Journal: Rev Soc Bras Med Trop (2020)
MeSH terms: Herpes Zoster Oticus / drug therapy, Herpes Zoster, Leishmaniasis, Cutaneous / drug therapy, Case Reports, Herpesvirus 3, Human, Humans, United States

Ramsay Hunt Syndrome (RHS), also known as herpes zoster oticus, is caused by the reactivation of varicella zoster virus (VZV) in the geniculate ganglion of the facial nerve. Herein, we report a case of Ramsey Hunt Syndrome in a patient after antimonial treatment for Cutaneous Leishmaniasis. The patient presented with microvesicles grouped on an erythematous base, starting in the neck and ascending towards the scalp margin on the right side of the head. The patient also developed grade V peripheral facial palsy the day after initiating the herpes zoster treatment, this outcome corroborated the assumption of Ramsey Hunt Syndrome.
An unusual case of aplastic anemia caused by temozolomide
Authors: Gazi Comez, Alper Sevinc, Ozlem Nuray Sever, Taner Babacan, Ibrahim Sarı, Celalettin Camci
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

Radiotherapy and concomitant/adjuvant therapy with temozolomide are a common treatment regimen for children and adults with high-grade glioma. Although temozolomide is generally safe, it can rarely cause life-threatening complications. Here we report a case of a 31-year-old female patient who underwent surgical resection followed by radiotherapy plus concomitant temozolomide. She developed pancytopenia after adjuvant treatment with temozolomide. A bone marrow aspiration and biopsy showed hypocellularity with very few erythroid and myeloid cells, consistent with aplastic anemia. In the English literature, aplastic anemia due to temozolomide is extremely rare.
Surgical wound infection caused by a multi drug resistant Streptococcus pneumoniae Serotype 19A after a total coloproctectomy with ileostomy
Authors: Nzoyikorera Néhémie, Khalid Zerouali, Idrissa Diawara, Khalid Katfy, Fakhreddine Maaloum, Sylvestre Kabura, Bahija Zaki, Chehab Farid, Houria Belabbes, Naima Elmdaghri
Journal: Pan Afr Med J (2020)
Keywords: streptococcus pneumoniae, serotype 19a, surgical wound infection
MeSH terms: Pneumococcal Infections / diagnosis, Streptococcus pneumoniae / isolation & purification, Surgical Wound Infection / diagnosis, Case Reports, Adult, Colectomy, Drug Resistance, Multiple, Bacterial, Female, Humans, Ileostomy, Morocco, Pneumococcal Infections / microbiology, Serogroup, Surgical Wound Infection / microbiology

Streptococcus pneumoniae (S. pneumoniae) colonizes asymptomatically the human nasopharynx. This pathogen is responsible for sinusitis, otitis media, pneumonia, bacteremia and meningitis. We report the case of a 35-year-old female patient who developed a surgical wound infection by a multi drug resistant S. pneumoniae serotype 19A after a total coloprotectomy. This first found in Morocco shows the implication of multidrug resistant S. pneumoniae in surgical wound infections.
Presurgical Rehearsals for Patients Considering "Awake" Deep Brain Stimulation
Authors: Ramsey A Falconer, Sean L Rogers, Cristie M Brewer, Franco Piscitani, Mahesh B Shenai
Journal: Front Surg (2016)
Keywords: dbs, parkinson’s disease, awake neurosurgery, patient experience, surgical simulation
MeSH terms: Case Reports

Simulated surgical environments are rapidly gaining adoption in training students, residents, and members of specialized surgical teams. However, minimal attention has been given to the use of simulated surgical environments to educate patients on surgical processes, particularly procedures that require the active participation of the patient. "Awake" neurosurgery provides a unique situation in which patients openly participate in their operation. We describe a case report, in which a 62-year-old male was referred for "awake" deep brain stimulation implantation, in relation to medically refractory Parkinson's disease. The patient had significant concerns regarding anxiety and claustrophobia, and toleration of the "awake" procedure. Consequently, we designed a simulated OR environment and process, to recreate the physical experience of the procedure, with minimal cost or risk. This experience was crucial in determining the care plan, as after this experience, the patient opted for an "asleep" alternative. Thus, in certain settings, presurgical rehearsals may have a dramatic impact in the overall course of care.
Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART)
Authors: Virin Ramoutar, Raafat Makary, Malleswari Ravi, Leighton James, Charles Heilig
Journal: Case Rep Nephrol (2020)
MeSH terms: Case Reports

Prior to the advent of combined antiretroviral therapy (cART), human immunodeficiency virus-associated nephropathy (HIVAN) was inevitably associated with rapidly progressive renal failure and dialysis dependence. HIV-1 seropositive patients often met with untimely deaths due to complications of end-stage renal disease (ESRD), opportunistic infections, or other HIV-related end-organ failure. Although the association between cART and improved outcomes in HIVAN has been recognized for over 20 years, no randomized trials have specifically examined this effect to date. In terms of reversal of dialysis-dependent renal failure after cART initiation, only a handful of case reports exist. The authors report a case of a 44-year-old Latino male requiring thrice-weekly haemodialysis in the setting of biopsy-proven HIVAN who was able to stop dialysis in 7 months after being initiated on cART.
Case report: binaural beats music assessment experiment
Authors: Elizabeth Krasnoff, Gaétan Chevalier
Journal: Front Hum Neurosci (2023)
Keywords: audio beats, auditory illusion, binaural beats, frequency following, neural response, neural rhythms
MeSH terms: Case Reports

We recruited subjects with the focus on people who were stressed and needed a break to experience relaxation. The study used inaudible binaural beats (BB) to measure the ability of BB to induce a relaxed state. We found through measuring brain wave activity that in fact BB seem to objectively induce a state of relaxation. We were able to see this across several scores, F3/F4 Alpha Assessment and CZ Theta Beta, calculated from EEG readings, that indicated an increase in positive outlook and a relaxing brain, respectively, and scalp topography maps. Most subjects also showed an improvement in Menlascan measurements of microcirculation or cardiovascular score, although the Menlascan scores and Big Five character assessment results were less conclusive. BB seem to have profound effects on the physiology of subjects and since the beats were not audible, these effects could not be attributed to the placebo effect. These results are encouraging in terms of developing musical products incorporating BB to affect human neural rhythms and corollary states of consciousness and warrant further research with more subjects and different frequencies of BB and different music tracks.
Case report: Emergency management of spontaneous rupture of the inflammatory myofibroblastic tumor of the urinary bladder
Authors: Zhenfu Sun, Lei Qi, Zhifan Guo, Wei Yuan, Yuancheng Du, Haitao Gao, Xuekai Hong, Yunjiang Zang
Journal: Front Oncol (2022)
Keywords: imtub, bladder tumor, partial cystectomy, pathology, spontaneous rupture
MeSH terms: Case Reports

Acute abdomen caused by spontaneous rupture of the inflammatory myofibroblastic tumor of the urinary bladder (IMTUB) is a rare clinical emergency of the urinary system.It is difficult to distinguish it from spontaneous rupture of bladder caused by other causes before surgery. An emergency case of spontaneous rupture of IMTUB was reported. A 57-year-old middle-aged woman was admitted to the hospital because of "acute lower abdominal pain for 5 hours". No history of smoking and gross hematuria. The physical examination revealed visible abdominal tenderness as well as signs of shock. A pelvic CT scan shows a space-occupying lesion above the bladder with massive accumulation of blood. When the nature of the tumor could not be determined, emergency laparotomy and partial cystectomy were performed, and postoperative pathology confirmed cystitis myofibroblastic tumor. No local recurrence or distant metastasis of the tumor was observed during the regular follow-up period of 6 months. IMTUB should focus on prevention and treatment, with a combination of preoperative examination and postoperative pathology, and finally implement highly individualized treatment.
Time of Anderson-Fabry Disease Detection and Cardiovascular Presentation
Authors: K Selthofer-Relatic
Journal: Case Rep Cardiol (2018)
MeSH terms: Case Reports

Background:
Anderson-Fabry disease is an X-linked inherited disease, which manifests in a different manner depending on gender and genotype. Making a working diagnosis of Anderson-Fabry disease is difficult because of several reasons: (a) that it is a multiorgan disease with wide variety of phenotypes, (b) different timelines of presentation, (c) gender differences, and (d) possible coexistence with other comorbidities. Late-onset/cardiac type of presentation with minimal involvement of other organs can additionally make diagnosis difficult.
Aim:
To describe different cardiac manifestations at different time points in the course of the disease: (1) 72-year-old female (echocardiography detection), heterozygote, significant left and mild right ventricular hypertrophy; (2) 62-year-old male (echocardiography detection), hemizygote, left ventricular hypertrophy, implanted cardiac pacemaker, a performed percutaneous coronary intervention after myocardial infarction, degenerative medium degree aortic valve stenosis; (3) 45-year-old female (asymptomatic/family screening), heterozygote, thickened mitral papillary muscle, mild left ventricular hypertrophy, first degree diastolic dysfunction; and (4) 75-year-old female (symptomatic/family screening), heterozygote, cardiomyopathy with reduced left ventricular ejection fraction after heart surgery (mitral valve annuloplasty and plastic repair of the tricuspid valve).
Conclusion:
All patients have Anderson-Fabry disease but with different clinical presentations depending on the gender, the type of mutation, and the time of detection. All these features can make the patients' profiles unique and delay the time of detection.
Recent applications of isotope analysis to forensic anthropology
Authors: Eric J Bartelink, Lesley A Chesson
Journal: Forensic Sci Res (2019)
Keywords: forensic sciences, forensic anthropology, isoscapes, provenancing, stable isotope analysis
MeSH terms: Review

Isotope analysis has become an increasingly valuable tool in forensic anthropology casework over the past decade. Modern-day isotopic investigations on human remains have integrated the use of multi-isotope profiles (e.g. C, N, O, H, S, Sr, and Pb) as well as isotopic landscapes ("isoscapes") from multiple body tissues (e.g. teeth, bone, hair, and nails) to predict possible region-of-origin of unidentified human remains. Together, data from various isotope analyses provide additional lines of evidence for human identification, including a decedent's possible region-of-birth, long-term adult residence, recent travel history, and dietary choices. Here, we present the basic principles of isotope analysis and provide a brief overview of instrumentation, analytical standards, sample selection, and sample quality measures. Finally, we present case studies that reflect the diverse applications of isotope analysis to the medicolegal system before describing some future research directions. As shown herein, isotope analysis is a flexible and powerful geolocation tool that can provide new investigative leads for unidentified human remains cases.
Screening for Q Fever during Other Bacterial Endocarditis in Endemic Areas: Our Experience with Three Patients
Authors: Said Younis, Michal Stein, Sharon Reisfeld
Journal: Case Rep Infect Dis (2019)
MeSH terms: Case Reports

Endocarditis is not a usual manifestation of acute Q fever. There is an ongoing debate about the need to screen patients for valvular diseases after acute Q fever. We present, for the first time, three patients with bacterial endocarditis from different aetiologies and a simultaneous diagnosis of acute Q fever. All were treated with prolonged antimicrobial treatment, and none of them developed a persistent Q infection. We suggest screening patients with endocarditis from other aetiologies to Q fever.
Imaging of auriculotemporal nerve perineural spread
Authors: Michael Chan, Adam A Dmytriw, Eric Bartlett, Eugene Yu
Journal: Ecancermedicalscience (2013)
Keywords: ct, mri, head and neck malignancy, perineural spread
MeSH terms: Case Reports

Importance:
Adenoid cystic carcinomas (ACCs) are relatively rare tumours, notorious for wide local infiltration and perineural spread. Perineural extension commonly occurs along branches of the trigeminal and facial nerves, and its presence represents a poor prognostic factor with implications for treatment approach.
Observations:
We report the case of a 61-year-old female presenting with worsening left facial numbness and weakness. On magnetic resonance imaging, the patient was found to have perineural spread of a left parotid tumour along the auriculotemporal nerve. There was involvement of the V2 and V3 branches of the trigeminal nerve. An ultrasound-guided biopsy of the mass demonstrated ACC.
Conclusions and relevance:
The auriculotemporal nerve may serve as a route for tumour spread, particularly in the setting of head and neck malignancy. Moreover, this particular suspicion should be raised when patients with known malignancy experience concomitant trigeminal (V) and facial (VII) nerve dysfunctions.
Wolff-Parkinson-white syndrome mimics a conduction disease
Authors: S Marrakchi, I Kammoun, S Kachboura
Journal: Case Rep Med (2014)

Background. It is important to recognise Wolff-Parkinson-White (WPW) syndrome in electrocardiograms (ECG), as it may mimic ischaemic heart disease, ventricular hypertrophy, and bundle branch block. Recognising WPW syndrome allows for risk stratification, the identification of associated conditions, and the institution of appropriate management. Objective. The present case showed that electrophysiological study is indicated in patients with abnormal ECG and syncope. Case Report. A 40-year-old man with Wolff-Parkinson-White syndrome was presented to emergency with syncope. A baseline ECG was a complete right branch block and posterior left hemiblock. He was admitted to the cardiac care unit for pacemaker implantation. The atypical figure of complete right branch block and posterior left hemiblock was thought to be a "false positive" of conduction abnormality. But the long anterograde refractory period of the both accessory pathway and atrioventricular conduction may cause difficulty in diagnosing Wolff-Parkinson-White syndrome, Conclusion. A Wolff-Parkinson-White Syndrome may mimic a conduction disease. No reliable algorithm exists for making an ECG diagnosis of a preexcitation syndrome with conduction disorders. This can lead to diagnostic and therapeutic dilemmas in the context of syncope.
Chronic Infection with Hidden Malignancy Mimicking the Clinical Presentation of an Autoimmune Disease
Authors: Ammar Bakhsh, Khalil Miyajan, Abdulghani Sadaqa, Amer Eisa, Ghali Faidah, Hani Almoallim
Journal: Case Rep Rheumatol (2022)
MeSH terms: Case Reports

Infections of the paranasal sinuses are common and usually occur in patients who are immunocompromised. Many atypical clinical presentations have been reported but rarely in the elderly population. We report a 71-year-old female patient with a 20-year history of an autoimmune disease who had recently become resistant to treatment. Her autoimmune symptoms significantly improved following resection of deeply seated bacterial infection in her paranasal sinuses. She was also diagnosed with cervical cancer. Clinicians should look carefully for hidden infections and/or malignancies in patients lacking response while on immunosuppressive therapy for autoimmune disease.
Adrenal crisis during pregnancy: Case report and obstetric perspective
Authors: Barbara Gardella, Andrea Gritti, Annachiara Licia Scatigno, Anna Maria Clelia Gallotti, Francesca Perotti, Mattia Dominoni
Journal: Front Med (Lausanne) (2022)
Keywords: adrenal crisis, adrenal gland, adrenal insufficiency, obstetric, pregnancy
MeSH terms: Case Reports

Adrenal dysfunction (AD) and, in particular, adrenal crisis are uncommon events in pregnant women, but associated with significant maternal and fetal morbidity and mortality if untreated or undiagnosed. Adrenal crisis may be confused with the common symptoms of pregnancy: the obstetricians should be able to promptly diagnose and treat it in order to avoid the adverse outcomes regarding the mother and the fetus. For this reason, AD must be treated by an expert multidisciplinary team. We presented a case report of a young pregnant woman with adrenal crisis due to tuberculosis, cocaine abuse, and massive bilateral hemorrhage with symptoms of emesis, hypotension, sudden abdominal pain, and leukocytosis. The most common issues of diagnosis and treatment are discussed and analyzed. Finally, we performed a review of the literature regarding adrenal crisis and adrenal insufficiency (AI) in pregnancy in order to clarify the management of these diseases in obstetrics setting.
Medial Migration of a Broken Trochanteric Cable
Authors: Bedri Karaismailoglu, Turgut Nedim Karaismailoglu
Journal: Case Rep Orthop (2018)
MeSH terms: Case Reports

Background:
Cerclage wires or cables are commonly being used in hip reconstruction procedures like primary (especially in patients with developmental hip dysplasia) or revision arthroplasty. Local or distant migration of a broken cable or wire is a complication that might lead to devastating situations depending on the route of migration.
Case presentation:
We report a case of a 40-year-old female who underwent bilateral total hip arthroplasty surgery due to bilateral developmental hip dysplasia. Trochanteric osteotomy was needed in her right hip to advance trochanter major distally. Trochanteric fixation was achieved by a cerclage cable system. Four years after the surgery, the patient referred to the hospital with a prominence and pain in her right inguinal area. Radiographies revealed medial migration of a broken trochanteric cable part. The possible route of the cable was through medial adductor muscles, posterior to the femoral neurovascular bundle and anterior to the sciatic nerve. Both migrated and remaining parts of the cable were extracted under general anesthesia.
Conclusion:
Broken cables should be followed carefully due to their sharpness and possible serious complications secondary to distant migration. Extraction might be inevitable in case of a close relation with neurovascular structures.
Neuromyelitis optica spectrum disease with positive autoimmune indices: a case report and review of the literature
Authors: M E Evangelopoulos, G Koutsis, E Andreadou, C Potagas, A Dimirakopoulos, C Sfagos
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

A 45-year-old female suffering from severe thoracic pain was admitted to the emergency department of our hospital. Thorough clinical examination revealed paresis of the left lower limb and sensory deficit at the level of the Th4 vertebra. MRI of the thoracic spine demonstrated a lesion at the level of Th1-Th7. Despite initial improvement following i.v. corticosteroid administration, the patient's clinical status deteriorated, with recurrence of myelitis and extension of the lesion to Th12. She developed paraparesis, hyperreflexia and spasticity of both legs, symmetrical sensory deficit below Th4, and sphincter dysfunction. Differential diagnosis included infectious, metabolic, neoplastic/paraneoplastic, and ischemic causes as well as multiple sclerosis. NMO IgG was found positive and led to the diagnosis of longitudinal extensive transverse myelitis (LETM) in the NMO spectrum disorders. Administration of immunosuppressive therapy resulted in gradual improvement of the patient's clinical status and stabilization for five years. In the setting of LETM, patients with antiaquaporin 4 IgGs can present features of coexisting systemic involvement. A thorough differential diagnosis is required to guide appropriate therapy.