OpenMed/multicare-articles huggingface dataset:
Urolithiasis-related ureteric intussusception: A rare case report
Authors: Hashim Homaida, Ibrahim A Khalil, Ahmed Haroon, Jamil Ahmad, Khalid Mahmoud, Hosam Tawfik, Abdelfattah Omran, Abdulqadir Alobaidy, Abdullah A Al-Ansari
Journal: Urol Case Rep (2023)
MeSH terms: Case Reports

Ureteral intussusception is a rare condition that historically occurs as a complication of ureteral neoplasms or iatrogenic endoscopic procedures. Although the exact mechanism of ureteral intussusception is unclear, most reported cases are due to leading points as malignant or benign masses. Urolithiasis related is rarely reported and can be challenging in stone management as it might decrease the spontaneous stone passage rate. In addition, it will increase the complexity of the endoscopic stone management. We present the second reported case of urolithiasis-related ureteric intussusception presented with urosepsis due to obstructive uropathy, successfully managed by an endourological approach.
Single dominant right coronary artery with hypoplastic left coronary branch: a rare congenital anomaly: a case report
Authors: Fadhel Hamidani, Blerim Berisha
Journal: Eur Heart J Case Rep (2024)
Keywords: case report, hypoplastic coronary artery, single coronary artery, sudden cardiac death
MeSH terms: Case Reports

Background:
A right single coronary artery (SCA) and hypoplastic coronary disease represent a rare coronary artery anomaly, which is associated with sudden cardiac death. The clinical manifestations of these anomalies depend on the distribution of collateral vessels.
Case summary:
A 55-year-old female presented with dyspnoea, mild chest pain during physical activity, and palpitations. Selective coronary angiography revealed a prominent SCA originating from the right coronary sinus. Approximately 2 mm from the ostium, this artery branched into two: a dominant right coronary artery (RCA) and a smaller artery for the anterior wall perfusion. The dominant RCA then moved posteriorly, bifurcating into a posterior descending artery and a posterolateral artery. The latter occupied the expected location of the left circumflex artery and supplied the majority of the coronary circulation, including the left ventricle. Notably, there were no significant atherosclerotic calcifications or stenoses observed.
Discussion:
We describe a unique case of a SCA that doesn't conform to any category within the modified Lipton's classification. Symptoms are speculated to arise from the compression of the SCA between the aorta and pulmonary artery during physical exertion. Additionally, hypoperfusion from the hypoplastic left coronary branch in the anterior wall warrants consideration. It's paramount to meticulously evaluate the risk of sudden cardiac death when treating patients with a SCA. For high-risk patients, coronary artery bypass grafting should be contemplated.For our patient, given the clinical context, pharmacological treatment optimization was chosen.
Inflammatory fibroid polyp of the small intestine presenting as small bowel obstruction with intussusception: a case report
Authors: Cian Hehir, Gavin Calpin, Gavin Dowling, Chloe Spillane, Clive Kilgallen, Arnold D K Hill
Journal: J Surg Case Rep (2024)
Keywords: adult intussusception, bowel obstruction, inflammatory fibroid polyp, spindle-cell
MeSH terms: Case Reports

Inflammatory fibroid polyps (IFP) are rare benign neoplasms most commonly occurring within the respiratory tract but are rarely also observed in the gastro-intestinal tract. Herein we present the case of a 73-year-old female presenting with ileo-ileal intussusception secondary to IFP. The patient was treated with emergency laparotomy with segmental bowel resection and primary anastomosis. Histopathological analysis of the excised bowel segment initially revealed a low-grade, mural based spindle cell neoplasm with surrounding benign, reactive lymphadenopathy. Immunohistochemical analysis demonstrated that the lesional cells stained positive for Vimentin, Smooth Muscle Actin (SMA), and CD34. On secondary analysis of the specimen, the morphology and immunohistochemical profile of the mass was in keeping with IFP. No invasive malignancy was identified. Such cases have been previously reported under the pseudonym 'the great mimicker', due to their striking similarity to malignant processes. This case report aims to add to the small body of research reporting such atypical presentations.
Renal venous sampling assisted the diagnosis of juxtaglomerular cell tumor: a case report and literature review
Authors: Di-En Yan, Hong-Bing He, Jian-Ping Guo, Yu-Lan Wang, Dan-Ping Peng, Huan-Huan Zheng, Xiao-Zi Zhou, Jin-Xiang Fu, Mei-Li Wang, Xian Luo, Yun-Feng Shen
Journal: Front Oncol (2024)
Keywords: hypokalemia, juxtaglomerular cell tumor, renal venous sampling, renin, resistant hypertension
MeSH terms: Case Reports

Juxtaglomerular cell tumor (JCT) is an endocrine tumor marked by elevated renin levels and high blood pressure. This case report presents the clinical findings of a 47-year-old woman with a history of recurrent hypokalemia, headaches, hypertension, and increased plasma renin activity (PRA). Dynamic enhanced magnetic resonance imaging (MRI) revealed a small nodule on the upper part of the right kidney. Selective renal venous sampling indicated a higher PRA only in the right upper pole renal vein. The patient underwent surgical removal of the right kidney mass, and the pathology results confirmed the diagnosis of JCT. This case underscores the importance of conducting selective renal venous sampling for accurate JCT diagnosis.
The epileptic blip syndrome
Authors: Edgar Matringe, Juan R Vidal, Marcela Perrone-Bertolotti, Laurent Vercueil
Journal: Epilepsy Behav Rep (2024)
Keywords: blip syndrome, consciousness stream, epilepsy, generalized spike-wave bursts
MeSH terms: Case Reports

We report on the case of an adolescent with juvenile myoclonic epilepsy exhibiting compulsory sporadic voluntary movement. These movements entailed the deliberate act of touching her forehead with her hand and were triggered by a short and indefinable cephalic sensation. Upon inquiry regarding the nature of this movement, the patient reported a sudden perception of a peculiar event localized "inside her head". In the course of a prolonged video-electroencephalographic recording, it appeared that the movements consistently followed the occurrence of diffuse Generalized Spike-and-Wave Bursts (GSWBs), lasting one to three seconds. This observation suggests that the impact of the GSWBs on the patient's stream of consciousness could be detected by the patient herself, who attributed it to an internal sensation, like a "blip on a screen". This clinical observation echoes the "blip syndrome", as described by the neurologist James W. Lance thirty years ago. These findings give some support that "blips" could be of an epileptic origin and lend weight to the notion that some patients could perceive their own EEG discharges. Moreover, this observation should be added to the perennial debate on the cognitive impact of intercritical discharges.
Case Report: A testicular torsion as an initial presentation of a patient with metastatic cecum signet-ring cell cancer
Authors: Bo Yu, Mi Meng, Rui Qin, Qiang Xu, Neng Zhang, Ni Fu
Journal: Front Oncol (2023)
Keywords: case report, colon cancer, pathological features, signet ring cell carcinoma, testicular metastases
MeSH terms: Case Reports

Secondary neoplasms of the testes from solid tumors are rare and usually present as a painless mass. Metastatic cecum signet-ring cell cancer of the testis is extremely rare. The orchioncus usually shows hypervascularity on color Doppler ultrasound. The present study reports an unusual case of testicular secondary signet-ring cell carcinoma mimicking missed testicular torsion in a 55-year-old male patient with right scrotal swelling and intermittent pain for 10 days. As color Doppler ultrasound showed an avascular distribution of the enlarged right testis, missed testicular torsion was initially diagnosed. Right-sided orchiectomy was performed, and pathology of the resected testis revealed an intestinal-type adenocarcinoma with mucinous and signet-ring cell features. This pathological feature led to further endoscopic colorectal biopsy of the digestive tract, which revealed poorly differentiated adenocarcinoma of the cecum with signet ring cell features similar to those of testicular specimens. In conclusion, differential diagnosis should be considered for rare testicular neoplasms, as was seen in this rare occurrence of testicular torsion in a patient who initially presented with metastatic colorectal cancer. A correct preoperative diagnosis can change the management and outcome. This report shares our reasons for misdiagnosis and opinions on diagnosing and treating this kind of case.
Think Outside the Heart: An Unusual Cause of Large Hemopericardium
Authors: Nabel Rajab Basha, Priscilla Wessly, Mohammed A Chamsi-Pasha
Journal: Methodist Debakey Cardiovasc J (2023)
Keywords: hemorrhagic pericardial effusion, invasive thymoma, mediastinal mass, pericardial effusion
MeSH terms: Cardiac Tamponade / diagnostic imaging, Cardiac Tamponade / etiology, Cardiac Tamponade / surgery, Pericardial Effusion / diagnostic imaging, Pericardial Effusion / etiology, Pericardial Effusion / surgery, Case Reports, Aged, Heart, Humans, Male, Medical Oncology, Multimodal Imaging

Pericardial effusions secondary to tumors are commonly metastatic, originating primarily from the lung, breast, and lymphomas. Pericardial tamponade is a rare oncological emergency warranting early identification and treatment. We describe a 66-year-old male found to have a large bloody pericardial effusion causing tamponade physiology, and multimodality imaging was consistent with intrapericardial malignancy with no identifiable primary source. He was subsequently diagnosed with type B3 thymoma after mediastinal resection.
The First Case of Huntington's Disease like 2 in Mali, West Africa
Authors: Abdoulaye Bocoum, Madani Ouologuem, Lassana Cissé, Fahmida Essop, Souleymane Dit Papa Coulibaly, Nadine Botha, Cheick A K Cissé, Alassane Dit Baneye Maiga, Amanda Krause, Guida Landouré, H3Africa consortium
Journal: Tremor Other Hyperkinet Mov (N Y) (2024)
Keywords: hdl2, jph3, mali, west africa
MeSH terms: Huntington Disease / genetics, Case Reports, Adult, Child, Family, Genetic Testing, Heterozygote, Humans, Mali, Middle Aged

Background:
Huntington's disease like 2 (HDL2) has been reported exclusively in patients with African ancestry, mostly originating from South Africa.
Case report:
We report three patients in Mali including a proband and his two children who have been examined by neurologists and psychiatrists after giving consent. They were aged between 28 and 56 years old. Psychiatric symptoms were predominant in the two younger patients while the father presented mainly with motor symptoms. Genetic testing identified a heterozygous 40 CTG repeat expansion in the Junctophilin-3 (JPH3) gene in all three patients.
Discussion:
This study supports the hypothesis that HDL2 may be widely spread across Africa.
Highlights:
We report here the first case of HDL2 in West Africa, suggesting that HDL2 is widely spread across African continent, and increasing access to genetic testing could uncover other cases.
Holography-guided procedural planning for modifying Venus P-valve implantation technique in patients with left pulmonary artery stents: a case-series
Authors: Angelo Fabio d'Aiello, Laura Schianchi, Francesca Bevilacqua, Paolo Ferrero, Angelo Micheletti, Diana Gabriela Negura, Giulia Pasqualin, Massimo Chessa
Journal: Front Cardiovasc Med (2024)
Keywords: venus p-valve, holographic models, left pulmonary artery stents, mixed reality, procedural planning, pulmonary valve, self-expandable valves
MeSH terms: Case Reports

Background:
Venus P-valve™ (Venus Medtech, Hangzhou, China) is a self-expandable bioprosthetic valve that can be transcatheter-implanted in native right ventricular outflow tract (RVOT) patients. Valve implantation is technically challenging. Due to the implantation technique, left pulmonary artery (LPA) stents represent a relative contraindication to Venus P-valve. In this case series, we describe our experience in implanting Venus P-valve in patients with previous LPA stents and the use of holographic models to facilitate procedural planning.
Methods and results:
From January to October 2023, 17 patients were scheduled for Venus P-Valve implantation. 16/17 (94%) patients were successfully implanted. 3/16 (18.7%) patients underwent Venus P-valve implantation with LPA stents. All patients underwent pre-operative CT scan. CT data set were employed to create three-dimensional (3D) holographic models (Artiness, Milan, Italy) of the entire heart, which were useful to plan valve implantation with a modified technique. Procedural success rate was 100%. No procedural complications occurred. All three patients presented good haemodynamic and angiographic results at discharge and follow-up visits.
Conclusion:
This case-series underscores the feasibility of Venus P-valve implantation in patients with previous LPA stents. The use of holographic models facilitated procedural planning in these challenging anatomical scenarios.
Factors associated with COVID-19 in children aged 0 to 15 in Niger, 2020
Authors: Habibatou Idé Amadou, Herman Yoda, Dieudonné Tialla, Pauline Kiswendsida Yanogo, Djibril Barry, Maman Laminou Ibrahim, Samaila Aboubacar, Abdoul Salam Youssoufou Souley, Abdoulaye Ousmane, Nicolas Meda
Journal: Pan Afr Med J (2024)
Keywords: covid-19, factors, niger, children, database
MeSH terms: COVID-19 / epidemiology, Case Reports, Adolescent, Child, Child, Preschool, Cross-Sectional Studies, Databases, Factual, Female, Humans, Infant, Infant, Newborn, Male, Niger / epidemiology, Risk Factors

On January 30, 2020, the WHO declared COVID-19 a global health emergency. Children were affected in less severe forms. Niger had implemented measures in a context where children were a source of contamination. The aim was to determine the factors associated with COVID-19 in children in Niger from February to August 2020 through an analysis of the national database. We conducted an analytical cross-sectional study including all COVID-19 suspects in the database. We used Excel and Epi Info 7.2.4. software for data extraction and analysis. Frequencies and proportions were calculated, and in a logistic regression, we estimated the ORs of association with their 95% confidence intervals, the factors associated with COVID-19 at the threshold of p<0.05. Of 572 notified cases of suspected COVID-19 in children aged 0-15, 11.36% were positive. The median age of infected children was 10 years [IQR: 5- 13 years]. The male/female sex ratio was 2.1. Children aged 11 to 15 accounted for 49.2%, 61.5% lived in Niamey, 4.6% had comorbidities. The notion of travel was 12.3% and 40% had a notion of contact, 24.4% had a fever, 23.2% had a cough, 18% were hospitalized, and a case-fatality rate of 1.5%. In etiological analysis, the factors associated with COVID-19 were sex ORa=0.51 [0.28-0.93] p=0.028, presence of symptoms ORa=2.29 [1.23-4.25] p=0.008 and notion of contact ORa=0.32 [0.13-0.77] p=0.011. Exposed children were sensitive to COVID-19, and all age groups were affected, with a predominance of males. We recommend barrier measures adapted to young people, and early detection and management of infected children.
Use of Tumguide® in the Insertion of a Nasogastric Tube Into the Stomach of a Patient With Creutzfeldt-Jakob Disease in a Nursing Home: A Case Report
Authors: Tomoya Iida, Yumi Kodama, Kazue Kogina
Journal: Cureus (2024)
Keywords: biologically transparent illumination, creutzfeldt-jakob disease, home care, nasogastric tube, tumguide®
MeSH terms: Case Reports

A 77-year-old woman exhibited a rapid progression of dementia and declining physical function and, over a period of about four months, reached a state of akinetic mutism. A final diagnosis of Creutzfeldt-Jakob disease (CJD) was made. A nasogastric tube was inserted into the stomach, and then it was confirmed on X-ray that the end of the tube was in the correct position. She was discharged to a nursing home, where she received home medical care after discharge. One month after the nasogastric tube insertion, Tumguide® was used to assist in replacing the tube at this home. In home care settings where an X-ray machine may not be available, Tumguide® may assist with nasogastric tube insertion.
An endoscopic-assisted contralateral paramedian supracerebellar infratentorial approach in the treatment of thalamic hemorrhage with hematoma extension into the brainstem: a case report
Authors: Eryi Sun, Siyuan Lu, Bo Chen, Qi Wu
Journal: Front Surg (2023)
Keywords: case report, contralateral paramedian supracerebellar infratentorial, endoscopic technology, paramedian supracerebellar infratentorial approach, thalamic hemorrhage with hematoma extension into the brainstem
MeSH terms: Case Reports

Objective:
Thalamic hemorrhage (TH) with hematoma extension into the brainstem can lead to poor outcomes. In this study, we discuss the feasibility of the endoscopic-assisted contralateral paramedian supracerebellar infratentorial (SCIT) approach as a therapeutic method for treating such patients.
Case presentation:
A patient suffered from a sudden loss of consciousness and right limb weakness, and a CT scan indicated TH with hematoma extension into the brainstem. She consented to undergo surgery by the endoscopic-assisted contralateral paramedian SCIT approach.
Results:
Now, the patient can open her eyes on her own and move her left arm in response to commands.
Conclusion:
The endoscopic-assisted contralateral paramedian SCIT approach may be a viable therapeutic method for treating TH patients with hematoma extension into the brainstem.
Huge Leiomyomas Arising from Bilateral Uterine Remnants in a Mayer-Rokitansky-Küster-Hauser Syndrome Patient with Coexisting Myotonic Dystrophy Type 1: A Case Report and Literature Review
Authors: Yukihiro Azuma, Koji Yamamoto, Mei Matsumoto, Hiroki Nagata, Ikumi Wada, Keisuke Miyamoto, Fuminori Taniguchi
Journal: Case Rep Obstet Gynecol (2023)
MeSH terms: Case Reports

Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is a rare congenital anomaly of the genital tract. Since the secretion of sex hormones from the ovaries is preserved, leiomyomas and adenomyomas, which are estrogen-dependent diseases, may develop from the uterine remnant. In contrast, patients with myotonic dystrophy type 1 (DM1), the most common dystrophy in adults, are considered to be at high risk for benign tumors of the female reproductive system, such as uterine leiomyomas and ovarian cysts. A rare case of huge leiomyomas arising from bilateral uterine remnants in a woman with MRKHS with coexisting DM1 is presented. Her chief complaint was abdominal distension. On pelvic magnetic resonance imaging (MRI), two solid pelvic masses showing low signal intensity on T2-weighted imaging were seen. Both the uterine corpus and cervix were unclear, but bilateral ovaries were observed normally on MRI. Two uterine leiomyoma-like masses connected by a band of fibrous tissue were found by laparotomy. As with the MRI findings, the uterine cervix and vagina could not be detected macroscopically. Normal bilateral adnexa and round ligaments were identified. All of her symptoms improved after hysterectomy.
A homozygous missense variant in the YG box domain in an individual with severe spinal muscular atrophy: a case report and variant characterization
Authors: Leping Li, Lalith Perera, Sonia A Varghese, Yael Shiloh-Malawsky, Senyene E Hunter, Tam P Sneddon, Cynthia M Powell, A Gregory Matera, Zheng Fan
Journal: Front Cell Neurosci (2023)
Keywords: african american, yg box, c796t>c variant, g27134t>g polymorphism, modeling, non-deletion, spinal muscular atrophy (sma)
MeSH terms: Case Reports

The vast majority of severe (Type 0) spinal muscular atrophy (SMA) cases are caused by homozygous deletions of survival motor neuron 1 (SMN1). We report a case in which the patient has two copies of SMN1 but clinically presents as Type 0 SMA. The patient is an African American male carrying a homozygous maternally inherited missense variant (c.796T>C) in a cis-oriented SMN1 duplication on one chromosome and an SMN1 deletion on the other chromosome (genotype: 2*+0). Initial extensive genetic workups including exome sequencing were negative. Deletion analysis used in the initial testing for SMA also failed to detect SMA as the patient has two copies of SMN1. Because of high clinical suspicion, SMA diagnosis was finally confirmed based on full-length SMN1 sequencing. The patient was initially treated with risdiplam and later gene therapy with onasemnogene abeparvovec at 5 months without complications. The patient's muscular weakness has stabilized with mild improvement. The patient is now 28 months old and remains stable and diffusely weak, with stable respiratory ventilatory support. This case highlights challenges in the diagnosis of SMA with a non-deletion genotype and provides a clinical example demonstrating that disruption of functional SMN protein polymerization through an amino acid change in the YG-box domain represents a little known but important pathogenic mechanism for SMA. Clinicians need to be mindful about the limitations of the current diagnostic approach for SMA in detecting non-deletion genotypes.
Welcoming new neighbors: Minnesota's rapid response model to address the urgent health needs of Afghan newcomers, 2021-2022
Authors: Mateo Frumholtz, William C Carlson, Patricia J Shannon, Sophia Iaquinta, Maggie Eckerstorfer, Brett Hendel-Paterson, Nasreen Quadri, Rashika Shetty, Hadia Mohammadzadah, William Stauffer, Opeyemi Adesida, Cindy Howard, Kailey Urban, Jonathan Kirsch, Mehria Sayad, Blain Mamo
Journal: Front Public Health (2024)
Keywords: afghanistan, operation allies welcome, immigration, public health response, refugees, trauma-informed care
MeSH terms: COVID-19 / epidemiology, Adult, Afghanistan, Female, Humans, Male, Minnesota, Primary Health Care, Refugees

As a result of the United States withdrawal from Afghanistan in fall 2021, 1,260 Afghan evacuees arrived in Minnesota between October 2021 and February 2022. Several contextual factors including an overtaxed health system under duress from COVID-19 and uncertain benefit eligibility prompted a coordinated public health response to appropriately address the acute and pressing medical concerns of our new neighbors. This community case study describes the State of Minnesota's cross-sectoral response that created a welcoming environment, identified public health concerns, and addressed acute medical needs. Medical volunteers provided an initial health and safety check for Afghan families upon arrival. Volunteers also offered onsite culturally and linguistically appropriate mental health assessments, group therapy, women's clinics, vaccine clinics, medication refills, and ongoing walk-in primary care. Care coordinators facilitated primary care and specialty care referrals. The majority (96%) of eligible arrivals were screened as part of this response and the median time between arrival to Minnesota and initial health screening was 2 days. Half of all arrivals screened reported at least one health concern and 56% were referred to a specialty for further evaluation. Almost one in four adults (24%) reported mental health concerns. Existing partnerships across local sectors can be leveraged to provide comprehensive physical and mental health services to newcomers in an emergency response.