OpenMed/multicare-articles huggingface dataset:
Detection of V. vulnificus septic shock with ARDS using mNGS
Authors: Tangjun Dan, Haidong Qin, CaiZhi Sun, Hua Shen, Lei Guo
Journal: Open Life Sci (2023)
Keywords: vibrio vulnificus, early diagnosis, metagenomic sequencing technology, septic shock
MeSH terms: Case Reports

The latest surveillance from the Centers for Disease Control and Prevention shows that the annual incidence of V. vulnificus infection is increasing. Unfortunately, in less well-known high-risk groups, this infection is usually excluded from differential diagnosis. Transmitted through wound exposure or ingestion, the mortality rate of foodborne diseases of V. vulnificus is the highest of all V. vulnificus. V. vulnificus is as lethal early diagnosis as Ebola and bubonic plague, so timely treatment is imperative. Sepsis caused by V. vulnificus infection mainly exists in the United States and is rarely reported in Southeast Asia. We report a 78-year-old man who went to the local hospital and complained of swelling in his right hand with severe pain. He ate raw salmon 2 days ago and denied other recognized seafood stab or trauma history and other seafood contact history. He was in septic shock at the time of treatment, so we immediately transferred to the emergency intensive care unit and tested for metagenomic next-generation sequencing (mNGS). The diagnosis was confirmed the second day after admission, and eventually he was cured and discharged from the hospital only after medical treatment, thus avoiding the risk of surgical debridement or even amputation. mNGS is helpful for early clinical diagnosis and effective early intervention for etiology, so that patients can get a good prognosis.
Acute Iatrogenic Agranulocytosis: A Rare and Dire Case of an Adverse Drug Reaction to Be Aware
Authors: Diogo André, Mónica Caldeira, Fabiana Gouveia, Rafael Nascimento, António Chaves, Maria Braza O
Journal: Case Rep Hematol (2020)
MeSH terms: Case Reports

Background:
Iatrogenic agranulocytosis (IA), by nonchemotherapeutic drugs, is a rare adverse event, resulting in a neutrophil count under 0.5 × 109 cells/L with fever or other suggestive signs of infection.
Methods:
This paper discusses the possible mechanisms responsible for agranulocytosis induced by nonchemotherapeutic drugs. It also describes three cases as well as potential ways to handle such iatrogenic situations.
Conclusion:
Neutropenia under 0.1 × 109 cells/L predispose patients to potentially fatal infections. Empiric broad-spectrum antibiotic and hematopoietic growth factors may be helpful in shortening hospitalization and prevent further infectious complications. Not all drugs associated with IA require frequent hematological monitoring, except medications such as clozapine, ticlopidine, and antithyroids.
Atypical Electrophysiological Findings in a Patient with Acute Motor and Sensory Axonal Neuropathy
Authors: Viviana Versace, Stefania Campostrini, Frediano Tezzon, Sara Martignago, Markus Kofler, Leopold Saltuari, Luca Sebastianelli, Raffaele Nardone
Journal: Front Neurol (2017)
Keywords: guillain–barré syndrome, acute motor and sensory axonal neuropathy, anti-ganglioside antibodies, axonal conduction failure, nodo-paranodopathy
MeSH terms: Case Reports

Guillain-Barré syndrome (GBS) is an immune-mediated polyradiculoneuropathy with acute onset and rapid clinical worsening; early diagnosis and immunomodulating therapy can ameliorate the course of disease. During the first days, however, nerve conduction studies (NCSs) are not always conclusive. Here, we describe a 73-year-old man presenting with progressive muscular weakness of the lower limbs, ascending to the upper limbs, accompanied by distal sensory disturbances. Neuroimaging of brain and spine and NCSs were unremarkable; cerebrospinal fluid analysis revealed no albuminocytologic dissociation. Based on typical clinical features, and on positivity for serum GD1b-IgM antibodies, GBS with proximal conduction failure at multiple radicular levels was postulated, and a standard regime of intravenous immunoglobulin was administered. Four weeks later, the patient presented with flaccid tetraparesis, areflexia, and reduction of position sense, tingling paresthesias, and initial respiratory distress. Repeat NCS still revealed almost normal findings, except for the disappearance of right ulnar nerve F-waves. A few days thereafter, the patient developed severe respiratory insufficiency requiring mechanical ventilation for 2 weeks. On day 50, NCS revealed for the first time markedly reduced compound muscle action potentials and sensory nerve action potentials in all tested nerves, without signs of demyelination; needle electromyography documented widespread denervation. The diagnosis of acute motor and sensory axonal neuropathy was made. After 3 months of intensive rehabilitation, the patient regained the ability to walk with little assistance and was discharged home. In conclusion, normal NCS findings up to several weeks do not exclude the diagnosis of GBS. Very proximal axonal conduction failure with late distal axonal degeneration should be taken into consideration, and electrodiagnostic follow-up examinations, even employing unusual techniques, are recommended over several weeks after disease onset.
Brucellosis presenting with pericarditis: case report and literature review
Authors: Fábio Lopes Pedro, Fernanda Paula Franchini, Leonardo Muraro Wildner
Journal: Case Rep Infect Dis (2013)

Pericarditis is a rare manifestation during the course of brucellosis. This paper describes a case of pericarditis associated with brucellosis in a 31-year-old veterinary physician with a past medical history of testicular tumor and reviews the cases of pericarditis associated with brucellosis in medical English literature.
Pulmonary sarcoidosis masquerading as metastatic breast cancer: a case report
Authors: Amol Dongre, Trupti Dongre, Mahesh Deshmukh, Suraj Agrawal, Niraj Kanchankar
Journal: Pan Afr Med J (2021)
Keywords: sarcoidosis, breast cancer, case report, intraductal carcinoma, non-caseating granuloma
MeSH terms: Breast Neoplasms / diagnosis, Lung Neoplasms / diagnosis, Sarcoidosis, Pulmonary / diagnosis, Case Reports, Breast Neoplasms / pathology, Female, Fluorodeoxyglucose F18, Humans, Lung Neoplasms / pathology, Lymph Nodes / pathology, Middle Aged, Positron-Emission Tomography, Sarcoidosis, Pulmonary / pathology, Fluorodeoxyglucose F18

Pulmonary lesions on imaging are presumed to be metastatic lesions in patients with breast cancer. Here, we report an interesting case of a 63-year-old lady with breast carcinoma showing pulmonary lesions on imaging suggestive of pulmonary metastases. Detailed evaluation of pulmonary lesions confirmed the presence of co-existing pulmonary sarcoidosis. Modern diagnostic methods like 18-flurodeoxyglucose positron emission tomography (18-FDG PET) are unable to clearly differentiate metastatic disease from granulomatous diseases like sarcoidosis. Thus, histological confirmation is needed for accurate staging and determining response to treatment and rarely, in non-responders, detecting any co-existing disease. This case emphasizes the need for detailed histopathological examination of lymph nodes in patients with non-responsive disease or recurrent disease despite adequate chemotherapy.
A Devasting Course of an Iliopsoas Muscle Abscess Subsequently Leading to Septic Shock, Septic Hip Arthritis, and Extended Gluteal Soft Tissue Necroses in an Elderly Immunocompromised Patient with Multiple Carcinomas: A Case Report and Brief Review of Literature
Authors: Ingo Schmidt
Journal: Open Orthop J (2018)
Keywords: biceps femoris muscle turnover flap, coverage, girdlestone resection-arthroplasty, iliopsoas muscle abscess, septic hip arthritis, septic shock, soft tissue defect
MeSH terms: Review

Background:
A devasting course of Iliopsoas Muscle (IPM) abscess remains a challenging therapeutic problem.
Methods:
A 69-year-old polymorbid male had a history of multiple carcinomas and presented with advanced stage of septic shock due to a right IPM abscess which communicated with the right hip joint and subsequently led to septic hip arthritis accompanied with post-infectious right gluteal deep soft tissue necroses. Management of surgical treatment included abscess revision, coverage with the use of Long Head Biceps Femoris Muscle (LHBFM) 180° turnover flap, and creating a Girdlestone resection-arthroplasty.
Results:
After a duration of patient's hospitalization of six months that included the necessity of artificial respiration over two months accompanied with in summary 18 required surgical procedures, the patient could be recovered successfully regarding his polymorbidity and his low-demand claims in activities of daily living with his Girdlestone resection-arthroplasty.
Conclusion:
Recovery of immunocompromised patients with those life-threatening situations can only be achieved by an interdisciplinary management. The LHBFM 180° turnover flap can be useful for filling off post-infectious deep soft tissue cavities communicating with the hip joint. The definitive Girdlestone resection-arthroplasty for treatment of septic hip arthritis is the method of choice for mobilization of elderly polymorbid patients with low demand claims in their activities of daily living.
Pancreatic transection due to blunt trauma
Authors: Amal Ankouz, Hicham Elbouhadouti, Jihane Lamrani, Khalid Ait Taleb, Abdelatif Louchi
Journal: J Emerg Trauma Shock (2010)
Keywords: pancreas, pseudocyst, transection, trauma
MeSH terms: Case Reports

Blunt fractures of the pancreas are rare and serious lesions. An isolated injury to the pancreas is uncommon. Physical signs and laboratory parameters are often inaccurate, and missing the diagnosis can cause serious clinical problems. We report a case of a 28-year-old woman with blunt pancreatic trauma in whom computed tomography revealed a fracture through the tail of the pancreas. It was complicated by pseudocyst formation. She was treated surgically with good outcome. This case is a reminder that pancreatic injuries should be considered in the differential diagnosis in cases of blunt abdominal trauma. Also, the clinician should be aware that when pancreatic injuries are managed conservatively, the clinical, radiological, and laboratory parameters need to be monitored till resolution.
Case Report of a Fatal Antifreeze Ingestion with a Record High Level and Impressive Renal Crystal Deposition
Authors: Heidi L Erickson
Journal: Case Rep Crit Care (2016)

Ethylene glycol, methanol, and diethylene glycol are readily available in many household and commercially available products. While these alcohols are relatively nontoxic themselves, their acidic metabolites are toxic and can result in significant morbidity and mortality. Herein we report a lethal case of massive ethylene glycol ingestion in a suicide with a record high level (1254 mg/dL) and images of the histologic examination of the kidneys revealing impressive calcium oxalate crystal deposition. Autopsy findings also showed evidence of mild cerebral edema.
"Is a picture really worth a thousand words?": A case study on classifying user attributes on Instagram
Authors: Junho Song, Kyungsik Han, Dongwon Lee, Sang-Wook Kim
Journal: PLoS One (2018)
MeSH terms: Social Media / statistics & numerical data, Research Support, Non-U.S. Gov't, Adolescent, Age Factors, Female, Humans, Machine Learning, Male, Models, Theoretical, Sex Factors, Surveys and Questionnaires

Because using social media has become a major part of people's daily lives, many of their personal characteristics are often implicitly or explicitly reflected in the content they share. We present a study of two personal characteristics-age and gender-related to user engagement on Instagram that can be determined through the characterization of images and tags. We demonstrate the strong influence of age and gender on Instagram use in terms of topical and content differences. We then build age and gender classification models that yield F1 scores of up to 88% and 74% in the detection of age and gender, respectively, and that better characterize users by images than by tags. We further demonstrate the robustness of our models using a new set of test data, with which the models exhibit greater overall performance than human raters. Our study highlights that future research should look to exploit images to a greater degree because they complement text and there are many unexamined images with no embedded text available.
Case report: Takotsubo syndrome induced by severe hypoglycemia
Authors: Panpan Xia, Yan Zhang, Yumin Sun, Jun Wang
Journal: Front Cardiovasc Med (2022)
Keywords: case report, heart failure, hypoglycemia, stress, takotsubo syndrome
MeSH terms: Case Reports

Background:
Takotsubo syndrome (TTS) is a disorder frequently characterized by transient dysfunction of the apical portion of the left ventricle with hyperkinesis in other parts of the heart walls. TTS is also called stress cardiomyopathy because it is known to be triggered by emotional or physical stress. We report a case of TTS associated with severe hypoglycemia.
Case summary:
An 85-year-old female patient with a history of non-insulin-dependent diabetes mellitus and hypertension presented to the emergency department with hypoglycemia-induced unconsciousness. The patient regained consciousness after an intravenous glucose injection. The patient complained of chest discomfort after the correction of hypoglycemia. Electrocardiography (ECG) revealed ST-segment elevation in leads V2-V5, therefore, ST-segment elevation myocardial infarction was highly suspected. Echocardiography showed impaired left ventricular systolic function with an ejection fraction of 40% accompanied by hypokinesis of the apex. Percutaneous coronary angiography showed 30% stenosis of the left anterior descending coronary artery. Left ventricular angiography revealed apical dyskinesia, which is typical of the classic apical ballooning shape of takotsubo. The patient was diagnosed with TTS and managed with pharmacological therapy, including antiplatelet (i.e., aspirin), lipid-lowering, anti-heart failure, and hypoglycemic drugs. The patient was successfully discharged in a stable condition.
Conclusion:
This is a representative case of TTS caused by hypoglycemia. Due to the self-limiting nature of TTS, diagnoses can be missed among hypoglycemic patients. Thus, echocardiography is required for patients with hypoglycemia to ensure an accurate TTS diagnosis in the emergency department.
Retiform Sertoli-Leydig Cell Tumor in a 38-Year-Old Woman: A Case Report, Retrospective Review, and Review of Current Literature
Authors: Laura C Nwogu, Josh A Showalter, Suvra Roy, Michael T Deavers, Bihong Zhao
Journal: Case Rep Pathol (2017)
MeSH terms: Case Reports

Ovarian sex cord-stromal tumors arise from the stromal cells that surround and support the oocytes. Sertoli-Leydig cell tumors belong to this category of ovarian neoplasms. We present the case of a 38-year-old woman who was found to have a right ovarian mass. The mass was resected and diagnosed as Stage I Sertoli-Leydig cell tumor, retiform variant, following histopathologic and immunohistochemical examination. This case is unusual given the rarity of the retiform variant of Sertoli-Leydig cell tumor and the atypically older age of 38 years at presentation.
Utility of a partially covered metal stent for salvage sealing therapy for bleeding caused by duodenal invasion of pancreatobiliary cancers: Case series
Authors: Yasunobu Yamashita, Hirofumi Yamazaki, Yuki Kawaji, Takashi Tamura, Keiichi Hatamaru, Masahiro Itonaga, Reiko Ashida, Masayuki Kitano
Journal: DEN Open (2023)
Keywords: advanced pancreatobiliary cancer, case series, covered self‐expandable metal stent, gastrointestinal bleeding, novel technique
MeSH terms: Case Reports

Pancreatobiliary cancer-related gastrointestinal bleeding caused by duodenal invasion can be a life-threatening condition that is hard to control. It is unclear whether a covered self-expandable metal stent (CSEMS) is useful for hemostasis of bleeding related to advanced pancreatobiliary cancer. The aim of this study was to evaluate the utility of a CSEMS for hemostasis of bleeding caused by duodenal invasion of pancreatobiliary cancer. Between January 2020 and January 2022, seven patients in whom a duodenal CSEMS was inserted to control pancreatobiliary cancer-related bleeding were enrolled. The technical and clinical success rates with respect to hemostasis, procedure time, and adverse events were assessed. All patients were inoperable cases (six with pancreatic cancer [five, stage IV; one, stage III]; and one with gallbladder cancer [stage IV]) in whom CSEMs were inserted to treat refractory bleeding caused by cancer invasion. Hemostasis was achieved in all cases (100% [7/7]). The mean procedure time was 17 ± 7.9 min. There were no adverse events, including migration and rebleeding. No rebleeding occurred up until the time of death in any of the cases (mean follow-up period, 73 ± 27 days). Deployment of duodenal CSEMS is a useful salvage therapy for bleeding caused by advanced pancreatobiliary cancer invasion.
Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
Authors: Michael Gilbertson, Annabel Tuckfield, Surender Juneja
Journal: Case Rep Hematol (2012)
MeSH terms: Case Reports

We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion.
Oral manifestations of sporotrichosis: A neglected disease
Authors: Aline-Corrêa Abrahão, Michelle Agostini, Tamires-Rocha de Oliveira, Cesar-Werneck Noce, Arley-Silva Júnior, Márcia-Grillo Cabral, Mário-José Romañach, Sandra-Regina Torres
Journal: J Clin Exp Dent (2023)
MeSH terms: Case Reports

Sporotrichosis is an uncommon subacute or chronic infection caused by Sporothrix spp. In some urban areas of Latin America, sporotrichosis has been considered an emergent cosmopolitan disease of zoonotic transmission by domestic cats. There are four different clinical forms of the disease: fixed cutaneous, lymphocutaneous, multifocal or disseminated cutaneous, and extracutaneous. The oral mucosa is rarely involved, usually as unspecified chronic ulcers in the context of multifocal or disseminated cutaneous form of systemic sporotrichosis. Microscopical features include chronic granulomatous inflammation containing microabscesses and fungal hyphae positive for Periodic acid Schiff and silver-based stains. The diagnosis of sporotrichosis is usually based on culture detection and strict correlation of clinical, microscopical and laboratorial data. We herein contribute with two additional illustrative cases of oral manifestation of sporotrichosis in immunocompromised patients from an endemic urban area from Rio de Janeiro-Brazil. Key words:Sporotrichosis, ulcer, oral cavity, immunosuppression.
Extra-Anatomic Jump Graft from the Right Colic Vein: A Novel Technique to Manage Portal Vein Thrombosis in Liver Transplantation
Authors: Paolo Magistri, Giuseppe Tarantino, Tiziana Olivieri, Annarita Pecchi, Roberto Ballarin, Fabrizio Di Benedetto
Journal: Case Rep Surg (2018)
MeSH terms: Case Reports

Background:
In the context of cirrhosis, portal vein thrombosis (PVT) is present in 2.1% to 26% of patients. PVT is no longer considered an absolute contraindication for liver transplantation, and nowadays, surgical strategies depend on the extent of PVT. Complete PVT is associated with higher morbidity rates and poor prognosis, while comparable long-term outcomes can be achieved as long as physiological portal inflow is restored.
Materials and methods:
We report our experience with a 45-year-old patient undergoing liver transplant with a PVT (stage III-b). To restore portal vein inflow to the liver, an extra-anatomic jump graft from the right colic vein with donor iliac vein interposition was constructed.
Results:
The patient recovered well, with a progressive improvement of the general conditions, and was finally discharged on p.o.d. 14. No anastomotic defects were found at the postoperative CT scan 10 months after the surgery.
Conclusion:
Our technical innovation represents a valid and safe alternative to the cavoportal hemitransposition, providing a proper flow restoration and reproducing a physiological setting, while avoiding the complications related to the cavoportal shunt. We believe that the reconstitution of liver portal inflow should be obtained with the most physiological approach possible and considering long-term liver function.
The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
Authors: Sucong Lyu, Guoqiang Zhong, Hui Chen, Jin Li, Mingsong Li
Journal: Case Rep Gastrointest Med (2023)
MeSH terms: Case Reports

The cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is now designated as morular cribriform thyroid carcinoma (CMTC) according to the 5th edition of the World Health Organization (WHO) Classification of Thyroid Tumors. CMTC can appear within a familial adenomatous polyposis (FAP) or be sporadic. We report the first case of a young female patient in China who was diagnosed with FAP and CMTC with a mutation in exon 16 of the APC gene underlying the disease. The main purpose of this case report is to provide a special pathological type of thyroid tumors, which is expected to be helpful for clinical work in the future.
Caecal Epiploic Appendagitis Masquerading Clinically as an Acute Appendicitis: A Case Report and Brief Literature Review
Authors: Tallat Ejaz, Eltaib Saad, Andik Nabil, James Slattery
Journal: Case Rep Surg (2019)
MeSH terms: Case Reports

A 46-year-old female presented to our emergency department (ED) with a 2-day history of right lower abdominal pain which was associated with nausea and anorexia. Abdominal examination revealed tenderness in the right iliac fossa (RIF) with rebound tenderness and a localized guarding. Urine dipstick was normal, and the pregnancy test was negative. Her laboratory investigations were significant only for a CRP of 16.6. A presumptive clinical diagnosis of acute appendicitis was suggested based on the given history and relevant physical signs. However, an abdominal computed tomography (CT) scan revealed an epiploic appendagitis of the caecum with a normal-looking appendix. She was managed conservatively and responded well and was discharged after 2 days in good health. Though being a relatively rare case of acute localized right-sided lower abdominal pain, caecal epiploic appendagitis should be considered as one of the differential diagnoses with the final diagnosis reached usually by the radiological findings due to the nonspecific nature of clinical and laboratory features.