OpenMed/multicare-articles huggingface dataset:
Diffuse Large B-Cell Lymphoma - Rare Presentation
Authors: Rodrigo Cordeiro, Mariana Chaves
Journal: J Belg Soc Radiol (2022)
Keywords: b-cell lymphoma, ct, diffuse large b-cell lymphoma, subcutaneous tissue, ultrasound
MeSH terms: Case Reports

Teaching Point: Subcutaneous nodules sparing the dermis and without extracutaneous involvement is a rare presentation of the diffuse large B-cell lymphoma.
Giant intrapulmonary teratoma: a rare case
Authors: Rayees Ahmad Dar, Majid Mushtaque, Sabiya Hamid Wani, Rayees Ahmed Malik
Journal: Case Rep Pulmonol (2011)
MeSH terms: Case Reports

Teratomas are tumors composed of tissues derived from more than one germ cell line. Pulmonary teratomas are rare and commonly involve the upper lobe of the left lung. Criteria for pulmonary origin are the exclusion of a gonadal or other extragonadal primary site and origin entirely within the lung. We report a case of a giant pulmonary teratoma in a 2-year-old male child and review the relevant literature.
Surgical Management of a Large Chronic Prepatellar Bursitis: 2-Stage Technique
Authors: Sriskandarasa Senthilkumaran, Steven W Hamilton
Journal: Case Rep Orthop (2020)
MeSH terms: Case Reports

Treatment of a large chronic prepatellar bursitis can be difficult to manage surgically because of a high rate of local complications and a significant chance of recurrence. We present a 2-stage technique using negative pressure dressings which produced a good outcome with no recurrence at one year after surgery.
Case Report: Rapid renal response to venetoclax monotherapy in a CLL patient with secondary membranous glomerulonephritis
Authors: Ester Lovato, Concetta Gangemi, Mauro Krampera, Carlo Visco, Isacco Ferrarini
Journal: Front Oncol (2023)
Keywords: autoimmune complications, chronic lymphocytic leukemia, membranous glomerulonephritis, nephrotic syndrome, venetoclax
MeSH terms: Case Reports

Membranous glomerulonephritis (MGN) is a rare extra-hematological autoimmune complication of chronic lymphocytic leukemia (CLL), clinically characterized by nephrotic-range proteinuria and, less frequently, renal failure. Because of the rarity of this condition, there is no standardized treatment. Chlorambucil and fludarabine-based regimens, possibly combined with rituximab, have been historically the most frequent therapeutic approaches, with renal response obtained in about two-third of the patients. However, responses are often transient and partial. Here we describe the first patient with rituximab-refractory, CLL-related MGN successfully treated with the Bcl-2 antagonist venetoclax. Nephrotic syndrome resolved as soon as three months after venetoclax initiation, with no unexpected toxicities. At the last follow-up, 17 months after venetoclax start, renal response persists, with proteinuria below 0.5 g/24 hours. This case suggests that targeted agents, particularly Bcl-2 antagonists, might be suitable options for patients with renal autoimmune disorders arising in the context of CLL.
A Pregnancy with Severe Hypertrophic Obstructive Cardiomyopathy after Surgery for an Implantable Cardioverter Defibrillator: A Case Report and Literature Review
Authors: Takashi Mitsui, Hisashi Masuyama, Kentaro Ejiri, Kei Hayata, Hiroshi Ito, Yuji Hiramatsu
Journal: Case Rep Obstet Gynecol (2016)

Hypertrophic obstructive cardiomyopathy (HOCM) is cardiac hypertrophy of ventricular myocardium with left ventricular outflow tract obstruction. We report a pregnancy with HOCM after defibrillator implantation surgery. The patient was a 33-year-old nulligravida and was categorized as New York Heart Association class II. Her brain natriuretic peptide (BNP) level was 724.6 pg/dL at preconception. She received careful pregnancy management. However, because frequent uterine contractions were observed at 25 weeks and 6 days of pregnancy, she was hospitalized, and magnesium sulfate was started as a tocolytic agent. At 27 weeks and 5 days of pregnancy, she had respiratory discomfort and orthopnea with a sudden decrease in peripheral oxygen saturation. Cardiac ultrasonography showed a worsened condition of HOCM and her BNP level was 1418.0 pg/mL. We performed an emergent cesarean section and she delivered a boy weighing 999 g. The Apgar score was 8 and 9 points at 1 and 5 minutes, respectively. The mother's heart failure quickly improved after birth and she was discharged at 10 days postoperatively. Fluctuations in circulatory dynamics during pregnancy may sometimes exacerbate heart disease. Therefore, the risks should be fully explained and careful assessment of cardiac function should be performed during pregnancy in patients with severe HOCM.
Post-traumatic massive hand lymphedema fully cured by vascularized lymph node flap transfer
Authors: Corinne Becker, Lionel Arrivé, Giuseppe Mangiameli, Ciprian Pricopi, Fanomezantsoa Randrianambinina, Francoise Le Pimpec-Barthes
Journal: SICOT J (2018)

Post-traumatic localized hand lymphedema is a rare situation and its diagnosis may be difficult, causing lack of care leading to failure of care. Our case study is of two young women with massive post-traumatic hand lymphedema who were treated for algodystrophy for 2 years, and whose bandages and physiotherapy were unsuccessful. Major social and psychological consequences due to difficulty with diagnosis and management resulting in inappropriate tests and therapeutic treatment were prescribed due to these issues. Noncontrast magnetic resonance lymphography revealed complete lymphatic vessel blockage in the hand and wrist. A vascularized lymph node flap harvested at the groin level was transferred to the elbow level 1 month after local dermolipectomy. These procedures resulted in the restoration of lymphatic flow. Both patients were definitely cured, and they returned to normal life within 6 months after surgery. Lymph node flap transfer associated with dermolipectomy may cure massive localized lymphedema in selected cases.
False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma-A Caution for Reporting Physicians
Authors: Paul Boré, Renaud Descourt, Luc Ollivier, Pierre-Yves Le Roux, Ronan Abgral
Journal: Front Med (Lausanne) (2018)
Keywords: mediastinal neoplasms, neoplasm staging, ovarian neoplasms, positron-emission tomography, schwannoma
MeSH terms: Case Reports

Schwannoma is a rare source of false-positive 18F-fluorodeoxyglucose (18F-FDG) uptake in Positron-emission tomography (PET/CT), inducing potential errors in staging of several solid cancer, with implications for patient management. This clinical case reports the situation of a patient undergoing an 18F-FDG-PET/CT for initial staging of an ovarian adenocarcinoma. We found a high paramediastinal hypermetabolic mass suspicious of remote extension or secondary synchronous primitive tumor. The biopsy finally reveals a histopathology of Schwannoma, allowing the patient to be eligible for a surgical procedure of her ovarian adenocarcinoma by rejecting the hypothesis of malignancy.
Pseudogout Associated Hip Pain in a Patient with HIV Infection
Authors: Benan M Dala-Ali, Matthew Welck, Mary Anne Lloyd, Henry D Atkinson
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

HIV infection is a global pandemic, currently affecting approximately 77,000 people in the UK and 33 million people around the world. The infection has widespread effects on the body and can involve the musculoskeletal system. It is therefore important that orthopaedic surgeons are aware of the condition and its sequelae. We present the case of a 46-year-old man with a 10-year history of HIV who presented with acute hip pain, difficulty weight-bearing, and constitutional symptoms. Following radiological, microbiological, and serological tests a diagnosis of pseudogout was established following microscopic analysis of the hip joint aspirate. The patient's symptoms resolved completely following the joint aspiration and NSAID therapy. Studies have shown a relationship between HIV infection and gout. The virus has also been linked to osteonecrosis, osteopenia, bone and joint tuberculosis, and septic arthritis from rare pathogens. However, it is difficult to fully ascertain whether these conditions are related to the HIV infection itself or the HAART (highly active antiretroviral therapy). There are no previously reported cases of HIV-infected patients with pseudogout. The case is discussed with reference to the literature.
Painless destructive thyroiditis in a patient with resistance to thyroid hormone: a case report
Authors: Tomoko Nagamine, Jaeduk Yoshimura Noh, Naoya Emoto, Takahito Kogai, Akira Hishinuma, Fumitaka Okajima, Hitoshi Sugihara
Journal: Thyroid Res (2019)
Keywords: painless thyroiditis, resistance to thyroid hormone, scintigraphy, thyroid
MeSH terms: Case Reports

Background:
Resistance to thyroid hormone (RTH) usually features a syndrome of inappropriate secretion of thyroid-stimulating hormone (SITSH) without suppression of the typical high thyroid hormone levels. However, some patients with RTH show thyroid-stimulating hormone (TSH) suppression due to thyrotoxicosis. We report a case of painless thyroiditis in a patient with RTH that was misdiagnosed as Graves' disease because of TSH-suppressed thyrotoxicosis.
Case presentation:
A sixteen-year-old boy consulted a local general physician for fatigue. He had a goiter, and biochemical analysis showed TSH < 0.1 μIU/mL, free triiodothyronine (FT3) of 2.70 pg/mL, and free thyroxine (FT4) of 3.6 ng/dL. He was diagnosed with Graves' disease and was treated with 20 mg thiamazole. One year later, he was referred to the department of endocrinology because of SITSH. He was finally diagnosed with RTH due to the finding of a heterozygous missense mutation (methionine 334 threonine) in the thyroid hormone receptor β gene. Three years after cessation of thiamazole, his hyperthyroxinemia showed marked exacerbation with TSH suppression. We diagnosed him with painless destructive thyroiditis because of low technetium-99 m (Tc-99 m) uptake in the thyroid. Extreme hyperthyroxinemia was ameliorated, with a return to the usual SITSH levels, within 1 month without any treatment.
Conclusion:
The present case demonstrates that diagnosing RTH is difficult when patients show hyperthyroxinemia with complete suppression of TSH to undetectable levels, and the data lead to misdiagnosis of RTH as Graves' disease. The initial diagnosis is important, and Tc-99 m scintigraphy is useful for the differential diagnosis of thyrotoxicosis accompanying RTH.
Intraparenchymatous adenomatoid tumor dependent on the rete testis: A case report and review of literature
Authors: A Jiménez Pacheco, J L Martínez Torres, F Valle Díaz de la Guardia, M A Arrabal Polo, A Zuluaga Gómez
Journal: Indian J Urol (2009)
Keywords: adenomatoid tumor, diagnosis and ultrasound
MeSH terms: Case Reports

The adenomatoid tumor is the most frequent paratesticular tumor. It is a benign tumor, which in women is mainly found in the uterus and the fallopian tubes, while in men it is most frequently found in the epididymis. These lesions may also affect the testicular albuginea, the spermatic cord and, in exceptional cases, the testicular parenchyma, of which there are only 4 published cases, the ejaculatory ducts, prostate, etc. The clinical signs and imaging studies are, on many occasions, difficult to differentiate from malign intratesticular solid tumor, which can result in unnecessary orchidectomies. We present a new case of intraparenchymatous adenomatoid tumor dependent on the rete testis.
Inflammatory myoglandular polyp of the cecum: case report and review of literature
Authors: Roberto L Meniconi, Roberto Caronna, Michele Benedetti, Gianfranco Fanello, Antonio Ciardi, Monica Schiratti, Federica Papini, Francesco Farelli, Giuseppe Dinatale, Piero Chirletti
Journal: BMC Gastroenterol (2010)
MeSH terms: Cecum / pathology, Cecum / surgery, Colonic Polyps / diagnosis, Colonic Polyps / surgery, Case Reports, Review, Colonic Polyps / pathology, Colonoscopy, Humans, Inflammation / pathology, Male, Middle Aged

Background:
Inflammatory myoglandular polyp (IMGP) is a rare non-neoplastic polyp of the large bowel, commonly with a distal localization (rectosigmoid), obscure in its pathogenesis. Up till now, 60 cases of IMGP have been described in the literature, but none located in the cecum.
Case presentation:
We report a case of a 53-year-old man who was admitted to our hospital for further evaluation of positive fecal occult blood test associated to anemia. A colonoscopy identified a red, sessile, lobulated polyp of the cecum, 4.2 cm in diameter, partially ulcerated. The histological examination of the biopsy revealed the presence of inflammatory granulation tissue with lymphocytic and eosinophil infiltration associated to a fibrous stroma: it was diagnosed as inflammatory fibroid polyp. Considering the polyp's features (absence of a peduncle and size) that could increase the risk of a polypectomy, a surgical resection was performed. Histological examination of the specimen revealed inflammatory granulation tissue in the lamina propria, hyperplastic glands with cystic dilatations, proliferation of smooth muscle and multiple erosions on the polyp surface: this polyp was finally diagnosed as IMGP. There was also another little polyp next to the ileocecal valve, not revealed at the colonoscopy, 0.8 cm in diameter, diagnosed as tubulovillous adenoma with low grade dysplasia.
Conclusions:
This is the first case of IMGP of the cecum. It is a benign lesion of unknown pathogenesis and must be considered different from other non-neoplastic polyps of the large bowel such as inflammatory cap polyps (ICP), inflammatory cloacogenic polyps, juvenile polyps (JP), inflammatory fibroid polyps (IFP), polyps secondary to mucosal prolapse syndrome (MPS), polypoid prolapsing mucosal folds of diverticular disease. When symptomatic, IMGP should be removed endoscopically, whereas surgical resection is reserved only in selected patients as in our case.
Bilateral Lipoadenoma of the Adrenal Glands and Humeral Brown Tumor: An Unusual Association
Authors: N Messaoudi, N Bouichrat, M Karrou, I Assarrar, S Malki, S Elmahjoubi, S Rouf, N Karich, A Lachkar, S Sefiani, M Bouziane, I Kamaoui, H Latrech
Journal: Case Rep Endocrinol (2021)
MeSH terms: Case Reports

Adrenal adenolipomas are rare lipomatous adrenal tumors that can be either functional or not. Only 7 cases have been reported in the English literature so far. However, brown tumors are benign, rare, historical lesions, with histological similarity to giant tumors that can be encountered in 1% of all primary hyperparathyroidism cases. We report the case of an unusual association of bilateral lipoadenoma of the adrenal glands and humeral brown tumor in a 35-year-old patient. He presented to the emergency department with a pathological fracture of the left humerus secondary to a brown tumor. The medical investigations have concluded to primary hyperparathyroidism. The screening for multiple endocrine neoplasia type 1 revealed the presence of bilateral nonsecreting adrenal masses whose anatomopathological study concluded adenolipomas. Adrenal tumors may constitute a part of multiple endocrine neoplasia type 1 in 20 to 40% of cases. In this view, it is necessary to check for the presence of other endocrine gland tumor locations such as primary hyperparathyroidism, neuroendocrine tumors of the duodenum and pancreas, or pituitary adenomas.
A novel SEMA6B variant causes adult-onset progressive myoclonic epilepsy-11 in a Chinese family: A case report and literature review
Authors: Yirao Chen, Xingyan Yang, Xinxiang Yan, Lu Shen, Jifeng Guo, Qian Xu
Journal: Front Genet (2023)
Keywords: sema6b, adult onset, case report, missense variant, progressive myoclonic epilepsy
MeSH terms: Case Reports

This study describes a patient with progressive myoclonic epilepsy-11 (EPM-11), which follows autosomal dominant inheritance caused by a novel SEMA6B variant. Most patients develop this disease during infancy or adolescence with action myoclonus, generalized tonic-clonic seizures (GTCS), and progressive neurological deterioration. No cases of adult-onset EPM-11 have been reported yet. Here, we present one case of adult-onset EPM-11 who experienced gait instability, seizures, and cognitive impairment, and harbored a novel missense variant, c.432C>G (p.C144W). Our findings provide a foundation for a better understanding of the phenotypic and genotypic profiles of EPM-11. Further functional studies are recommended to elucidate the pathogenesis of this disease.
A Rare Case of Burkholderia cepacia Complex Septic Arthritis
Authors: John Koo, Gregory D Deans
Journal: Case Rep Infect Dis (2018)
MeSH terms: Case Reports

Bacteria of the Burkholderia cepacia complex have rarely been reported to cause septic arthritis. Cases have been reported in patients who were immunocompromised, at extremes of age or who had history of steroid injection or penetrating trauma. A 67-year-old man with a history of opioid use disorder, osteoarthritis, and gout but no known immunocompromise was admitted to hospital with pain and swelling of his right knee. Cultures of synovial fluid and urine grew Burkholderia cepacia complex. Microscopy of synovial fluid also identified intracellular calcium pyrophosphate crystals. The patient's symptoms improved with joint irrigation and debridement and prolonged antimicrobial therapy. This case highlights the importance of diagnostic aspiration of an acutely inflamed joint to obtain a specific etiological diagnosis.
Primary hepatic non-Hodgkin's lymphoma with rectal cancer: A case report
Authors: Guo-Bin Wu, Chao-Yuan Huang, Shan Huang, Hai-Ming Ru, Bang-DE Xiang, Wei-Ping Yuan, Fei-Xiang Wu, Jian-Yong Liu, Zhi-Ming Zhang, Liang Ma, Zu-Shun Chen, Yin-Nong Zhao, LE-Qun Li
Journal: Oncol Lett (2015)
Keywords: liver, non-hodgkin’s lymphoma, primary liver lymphoma, rectal cancer

Primary hepatic non-Hodgkin's lymphoma (NHL) is an extremely rare disease that is commonly neglected as a possible diagnosis. The present study reports the case of a middle-aged male with chronic hepatitis B in which primary hepatic NHL and rectal cancer occurred simultaneously. A large solitary tumor in the left lobe of the liver was incidentally detected on routine examination prior to the laparoscopic resection of the rectal cancer. Laparoscopic resection of the rectal cancer and a liver biopsy were performed simultaneously. The pathology revealed that the hepatic tumor was NHL and that the rectal cancer was adenocarcinoma. Systemic staging revealed no evidence of nodal or bone marrow involvement, therefore, primary hepatic lymphoma (PHL) was diagnosed. PHL associated with rectal adenocarcinoma is extremely rare and to the best of our knowledge, has never been reported. At present, the cause and most effective therapy for the condition remain unclear.
Urinary schistosomiasis: report of case diagnosed in bladder biopsy
Authors: Hafsa Chahdi, Amal Damiri, Mohamed Reda El Ochi, Mohamed Allaoui, Abderrahmane Al Bouzidi, Mohamed Oukabli
Journal: BMC Clin Pathol (2018)
Keywords: bladder diseases, hematuria, schistosomia haematobium
MeSH terms: Case Reports

Background:
Urinary schistosomiasis is a common parasitic disease in endemic countries.
Case presentation:
We report the case of a patient who was on a working trip to Mauritania. This parasitosis, suspected in the presence of hematuria and the notion of stay in an endemic zone, was confirmed by the presence of Schistosoma heamatobium eggs during the histological examination of the bladder biopsy performed after cystoscopy, highlighting a bilharzial granuloma and of course, the diagnosis was confirmed by the presence of eggs during the direct examination of the freshly collected urine.
Conclusions:
It should be pointed out that the diagnosis of schistosomiasis must be evoked with the association of hematuria and the particular inflammatory aspect of the vesical mucosa and, of course, the notion of stay in an endemic zone.
Decoronation: An Alternative Treatment for Replacement Root Resorption
Authors: Marianne Sala, Asunción Mendoza-Mendoza, Rosa-María Yañez-Vico
Journal: Case Rep Dent (2017)
MeSH terms: Case Reports

Introduction:
Ankylosis and disrupted or altered root development are frequent complications associated with intrusive luxation and tooth avulsion lesions. Various forms of treatment have been described according to the severity of the trauma and root development. The literature shows that decoronation is an ideal treatment in cases where replacement resorption occurs.
Methods:
Two clinical cases are presented: involving intrusive luxation [15-year-old female patient with an affected maxillary left lateral incisor (2.2)] and a replanted avulsed tooth [8-year-old male patient with avulsion of the right maxillary central incisor (1.1)]; both cases presented advanced root resorption so that decoronation with a prosthetic tooth replacement was decided as the final treatment option.
Results:
In the short-term follow-up, patients were asymptomatic and had no functional problems. Radiographs showed that crestal bone height had been preserved.
Conclusions:
Preserving the decoronated root in the alveolar process not only helps to maintain bone volume but also enables vertical bone growth and facilitates the future insertion of an implant.
Fungal brain abscesses caused by Acremonium species
Authors: Hamdy Ibrahim, Mostafa ALfishawy, Attaa Ali, Safwat Abdel Maksod, Magdy Khorshed, Hanan Rady, Ahmed Alsisi, Adel Mohamed, Omar Alkassas, Marwa Haron, Suzan Saied
Journal: Egypt J Intern Med (2023)
Keywords: acremonium, covid-19, fungal abscesses
MeSH terms: Case Reports

Unusual fungal agents that exist environmentally as saprophytes can often lead to opportunistic infections, hyalohyphomycosis is a group of fungal infections caused by fungi characterized by hyaline septate hyphae and can infect both immunocompetent as well as immunocompromised patients, and Acremonium has drawn the attention of clinicians and microbiologists, as a potential pathogen in patients with and without underlying risk factors. It has also been increasingly implicated in systemic fungal diseases. Herein, we describe a case presentation of an immunocompromised patient with fungal brain abscesses due to Acremonium species.
Paraneoplastic pemphigus presenting as mild cutaneous features of pemphigus foliaceus and lichenoid stomatitis with antidesmoglein 1 antibodies
Authors: Yayoi Niimi, Bungo Ohyama, Giovanni Di Zenzo, Valentina Calabresi, Takashi Hashimoto, Seiji Kawana
Journal: Dermatol Res Pract (2010)
MeSH terms: Case Reports

Herein, we report a case of paraneoplastic pemphigus with mild skin features of pemphigus foliaceus and lichenoid stomatitis associated with B-cell lymphoma. A 49-year-old man presented with scattered blisters and erosions on the trunk along with mucosal blisters and erosions. Skin biopsy showed subcorneal acantholytic bulla and oral mucosal biopsy demonstrated lichenoid dermatitis. Direct immunofluorescence showed cell surface deposits of IgG and C3. Indirect immunofluorescence identified circulating IgG autoantibodies to the cell surfaces of normal human skin and also on the transitional epithelium of rat bladder. Enzyme-linked immunosorbent assay using recombinant baculoproteins showed positive antidesmoglein 1 autoantibodies (index 46) but negative antidesmoglein 3 autoantibodies (index 8). Immunoblot analysis using normal human epidermal extract detected BP230 and the 190 kDa periplakin, while immunoprecipitation using radiolabeled cultured keratinocyte immunoprecipitated BP230 and the 210 kDa envoplakin. We consider that the skin lesion was produced by humoral immunity whereas the oral lesion was produced by cellular immunity.