OpenMed/multicare-articles huggingface dataset:
Imported case of acute respiratory tract infection associated with a member of species nelson bay orthoreovirus
Authors: Atsushi Yamanaka, Akira Iwakiri, Tomoki Yoshikawa, Kouji Sakai, Harpal Singh, Daisuke Himeji, Ikuo Kikuchi, Akira Ueda, Seigo Yamamoto, Miho Miura, Yoko Shioyama, Kimiko Kawano, Tokiko Nagaishi, Minako Saito, Masumi Minomo, Naoyasu Iwamoto, Yoshio Hidaka, Hirotoshi Sohma, Takeshi Kobayashi, Yuta Kanai, Takehiro Kawagishi, Noriyo Nagata, Shuetsu Fukushi, Tetsuya Mizutani, Hideki Tani, Satoshi Taniguchi, Aiko Fukuma, Masayuki Shimojima, Ichiro Kurane, Tsutomu Kageyama, Takato Odagiri, Masayuki Saijo, Shigeru Morikawa
Journal: PLoS One (2014)
MeSH terms: Orthoreovirus, Reoviridae Infections / virology, Respiratory Tract Infections / virology, Case Reports, Research Support, Non-U.S. Gov't, Acute Disease, Adult, Humans, Japan, Male, Reoviridae Infections / transmission, Respiratory Tract Infections / transmission

A Japanese man suffered from acute respiratory tract infection after returning to Japan from Bali, Indonesia in 2007. Miyazaki-Bali/2007, a strain of the species of Nelson Bay orthoreovirus, was isolated from the patient's throat swab using Vero cells, in which syncytium formation was observed. This is the sixth report describing a patient with respiratory tract infection caused by an orthoreovirus classified to the species of Nelson Bay orthoreovirus. Given the possibility that all of the patients were infected in Malaysia and Indonesia, prospective surveillance on orthoreovirus infections should be carried out in Southeast Asia. Furthermore, contact surveillance study suggests that the risk of human-to-human infection of the species of Nelson Bay orthoreovirus would seem to be low.
Therapeutic hypothermia as a neuroprotective strategy in newborns with perinatal asphyxia-case report
Authors: Nayara Rodrigues Gomes de Oliveira, Gustavo Gonçalves Teixeira, Kathlen Terezinha Montes Soares Fernandes, Marla Moreira Avelar, Maja Medeiros, Cibelle Kayenne Martins Roberto Formiga
Journal: Front Rehabil Sci (2023)
Keywords: case report, child development, hypothermia, hypoxic-ischemic encephalopathy, perinatal asphyxia
MeSH terms: Case Reports

Background:
Perinatal asphyxia is a public health problem and the third major cause of death among children under 5 years.
Objective:
Two clinical cases of newborns with perinatal asphyxia submitted to therapeutic hypothermia and the follow-up of their motor development after hospital discharge have been reported.
Methods:
This retrospective case report study included two newborns with hypoxic-ischemic encephalopathy due to perinatal asphyxia who received a hypothermia protocol at the neonatal intensive care unit (NICU). The two newborns and their families were followed up at the outpatient clinic and assessed using the Hammersmith Child Neurological Examination, Alberta Child Motor Scale, and Denver Developmental Screening Test-II.
Results:
The newborns were submitted to a 72-hour hypothermia protocol. One newborn remained for 13 days in the NICU, while the other remained for 22 days. According to the multidisciplinary team, both cases presented with typical motor development with no cerebral palsy during the follow-up.
Conclusion:
Both cases showed positive results and a good prognostic for motor development. Therapeutic hypothermia may be a strategy to prevent neurologic sequelae in newborns with perinatal asphyxia, including cerebral palsy.
Detection of an MN1::ETV6 Gene Fusion in a Case of Acute Myeloid Leukemia with Erythroid Differentiation: A Case Report and Review of the Literature
Authors: Lauren A Choate, Liuyan Jiang, Mariam I Stein, Wei Shen, Linda B Baughn, Jess F Peterson
Journal: Case Rep Hematol (2023)
MeSH terms: Case Reports

The MN1::ETV6 gene fusion resulting from t(12;22)(p13;q12) has been rarely reported in myeloid neoplasms. We describe a 69-year-old male with newly diagnosed acute myeloid leukemia (AML) with erythroid differentiation and t(12;22)(p13;q12) demonstrated by conventional chromosome studies. Subsequent fluorescence in situ hybridization studies demonstrated a balanced ETV6 gene rearrangement (at 12p13). To further characterize this translocation, whole-genome sequencing was performed which confirmed t(12;22) with breakpoints involving the MN1 and ETV6 genes. Herein, we describe our case and review the literature to summarize the clinical and laboratory findings in patients with this rare but recurrent MN1::ETV6 gene fusion observed in myeloid neoplasms. Importantly, this case expands the clinical spectrum associated with the MN1::ETV6 gene fusion to include AML with erythroid differentiation. Lastly, this case demonstrates the importance of moving toward more comprehensive molecular testing to fully characterize the driver events in neoplastic genomes.
Primary Osteosarcoma of the Breast: A Rare Case Report and Literature Review
Authors: Shike Li, Qingfeng Xue, Wenyu Shi
Journal: Front Oncol (2022)
Keywords: extraskeletal osteosarcoma, extraskeletal osteosarcoma of the breast, osteosarcoma, primary osteosarcoma of the breast, thoracic oncology
MeSH terms: Case Reports

Background:
Primary osteosarcoma of the breast (POB) is an extremely aggressive and heterogeneous neoplasm that originates from nonepithelial elements of the mammary gland and accounts for fewer than 1% of breast cancers and fewer than 5% of all sarcomas.
Case presentation:
An 83-year-old Chinese woman went to our hospital because of a palpable mass she had had for 8 months in the left breast accompanied by persistent dull pain for 10 days. This mass was initially misdiagnosed as a degenerating fibroadenoma and was graded as probably benign (BI-RADS category 3) by ultrasonography (US) and computed tomography (CT) plain scan and contrast enhancement of chest. Eight months later, it was presumed to be highly malignant and graded as BI-RADS category 4C because of its rapid growth and more calcifications by US and CT. 99mTc-MDP whole-body bone imaging showed that there was a mass-like abnormal radioactive concentration of Tc-99m outside the bone of the left chest. The lumpectomy of the left breast was indicated, and the pathological findings were POB. She succumbed to respiratory failure caused by multiple lung metastases 4 months after the operation.
Conclusion:
POB is rare, and US and CT cannot reliably distinguish the causes of calcified breast masses between benign and malignant tumors. It can be diagnosed by pathology when metaplastic carcinoma, malignant phyllodes tumor, or carcinosarcoma containing osteoid and bone is excluded. This case could help clinicians to improve the prognosis and treatment of this disease.
Small intestinal angiosarcoma masquerading as an appendiceal abscess
Authors: D S H Liu, H Smith, M M W Lee, M Djeric
Journal: Ann R Coll Surg Engl (2013)
MeSH terms: Abscess / diagnosis, Appendix, Cecal Diseases / diagnosis, Hemangiosarcoma / diagnosis, Ileal Neoplasms / diagnosis, Case Reports, Abdomen, Acute / etiology, Adult, Diagnosis, Differential, Female, Humans, Intestinal Obstruction / etiology, Tomography, X-Ray Computed

Angiosarcomas of the small intestine are rare and present non-specifically. They usually manifest with abdominal discomfort, altered bowel habits, anaemia and gastrointestinal bleeding. Diagnosis is often challenging and occurs at an advanced tumour stage. We describe a case of a terminal ileum angiosarcoma masquerading as an appendiceal abscess, and discuss salient clinicopathological features in diagnosing and managing this disease.
Acute Liver Failure in a Pediatric Patient with Tetralogy of Fallot following Cardiac Catheterization
Authors: Irim Salik, Jasmeet Easwar, Michael Jacoby
Journal: Case Rep Anesthesiol (2020)
MeSH terms: Case Reports

A 4-month-old female with Tetralogy of Fallot (TOF) developed acute liver failure (ALF) following a cardiac catheterization procedure to correct severe stenosis of her right ventricular outflow tract (RVOT) conduit via balloon angioplasty. Cardiac history included TOF, heterotaxy syndrome, ipsilateral pulmonary veins, interrupted inferior vena cava (IVC) with azygos continuation, patent ductus arteriosus (PDA), and pulmonary atresia that was repaired with a right ventricle (RV) to pulmonary artery (PA) conduit. This is the first case described of its kind to our knowledge. Consent was obtained from the patient's family to publish this case report.
Considerations in Neuromuscular Blockade in the ICU: A Case Report and Review of the Literature
Authors: Jessica D Workum, Stephanie H V Janssen, Hugo R W Touw
Journal: Case Rep Crit Care (2020)
MeSH terms: Case Reports

Neuromuscular blocking agents are regularly used in the intensive care unit (ICU) to facilitate mechanical ventilation in patients with acute respiratory distress syndrome and patient-ventilator dyssynchronies. However, prolonged neuromuscular blockade is associated with adverse effects like ICU-acquired weakness. Residual neuromuscular blockade is, however, not routinely monitored in the intensive care unit, and as such, this phenomenon might be unrecognized and underreported. We report a case in which an unusual prolonged effect of neuromuscular blockade was seen after cessation of the drug, which illustrates the complexity of neuromuscular blockade in the ICU. We advocate for the use of train-of-four measurements in the ICU, recommend to choose cisatracurium over rocuronium in critically ill patients due to their pharmacokinetics when continuous neuromuscular blockade is considered, and propose a subsequent strategy once the choice has been made to start neuromuscular blockade.
The Impact of Scientific and Technical Training on Improving Routine Collection of Antenatal Care Data for Maternal and Foetal Risk Assessment: A Case Study in the Province of South Kalimantan, Indonesia
Authors: Dewi Anggraini, Mali Abdollahian, Kaye Marion, Supri Nuryani, Fadly Ramadhan, Rezky Putri Rahayu, Irfan Rizki Rachman, Widya Wurianto
Journal: J Pregnancy (2018)
MeSH terms: Attitude of Health Personnel, Data Collection / standards, Electronic Health Records / statistics & numerical data, Midwifery / education, Prenatal Care / methods, Adult, Female, Humans, Indonesia, Middle Aged, Midwifery / standards, Pregnancy, Pregnancy Complications / diagnosis, Prospective Studies, Qualitative Research, Retrospective Studies, Risk Assessment, Surveys and Questionnaires

Objectives:
First, to assess the impact of scientific and technical training on midwives' abilities in collecting and recording the results of routine antenatal care examinations. Second, to explore midwives' views with regard to factors affecting their abilities to successfully complete the data documentation tasks.
Methods:
The study was conducted in South Kalimantan, Indonesia (April 2016-October 2017). Nineteen urban and rural midwives were selected. Access to antenatal care information on 4,946 women (retrospective cohort study) and 381 women (prospective cohort study) was granted. A descriptive and exploratory design was used to describe midwives' abilities and challenges pertaining to timely collection and recording of results concerning antenatal care examinations.
Results:
Scientific and technical training has significantly improved the average amount of recorded antenatal care data (from 17.5% to 62.1%, p-value < 0.0005). Lack of awareness, high workload, and insufficient skills and facilities are the main reasons for the database gaps.
Conclusions:
The training has equipped midwives with scientific knowledge and technical abilities to allow routine collection of antenatal care data. Provision and adequate use of this information during different stages of pregnancy is crucial as an evidence-based guideline to assess maternal and foetal risk factors to ending preventable mortality.
Benign Mucosal Membrane Pemphigoid as a Differential Diagnosis of Necrotizing Periodontal Disease
Authors: Carmen Lucia Mueller Storrer, Darlan Rigo Junior, Lucimari Teixeira, Eugênio Esteves Costa, Brayan Ruppenthal Endres, Diogo Vinícius Ferreira Dos Santos, Aline Monise Sebastiani
Journal: Case Rep Dent (2020)
MeSH terms: Case Reports

Desquamative gingivitis is an oral sign of systemic changes that may be symptomatic or asymptomatic. It is generally related to immunological changes. This report is aimed at describing the case of a 51-year-old female patient, who presented with clinical desquamative gingivitis and was initially diagnosed and treated as necrotizing periodontal disease, but no improvement. The cause was hypothesized to be an autoimmune disease. Drug therapy was initiated as a combination of prednisone and topical clobetasol propionate 0.5% cream twice a day. After this treatment, there was an improvement in pain and the blistering of the gingiva. However, the gingiva remained erythematous. A biopsy led to the diagnosis of benign mucous membrane pemphigoid (BMMP). The BMMP case reported in this article has been successfully treated with systemic and topical immunosuppressive therapy. The efficacy of systemic corticosteroids with dapsone and multidisciplinary follow-up has been highlighted and can lead to the stabilization and adequate control of the disease.
New-Onset Cervical Lymphadenopathy in a Patient Undergoing Treatment of Pulmonary Mycobacterium avium Complex Infection: Toxoplasmosis Lymphadenitis
Authors: Chia-Yu Chiu, Amara Sarwal, Peter Yangga, Dasol Kang, Addi Feinstein
Journal: Case Rep Infect Dis (2020)
MeSH terms: Case Reports

Immunocompetent hosts with toxoplasmosis are usually asymptomatic. However, T. gondii can present as an acute systemic infection. Symptomatic patients usually have a benign, self-limited course that typically lasts from a few weeks to months. Herein, we present a 66-year-old immunocompetent female who developed dysphagia and new-onset cervical lymphadenopathy during pulmonary Mycobacterium avium complex treatment.
Chronic Idiopathic Thrombocytopenia Purpura and Helicobacter pylori Eradication: A case study
Authors: Santosh K Tiwari, Manoj G, Aleem A Khan, Aejaz Habeeb, Chittoor M Habibullah
Journal: Gastroenterology Res (2009)
Keywords: helicobacter pylori, eradication, idiopathic thrombocytopenic purpura, platelet
MeSH terms: Case Reports

Idiopathic thrombocytopenic purpura (ITP) is an immune-mediated thrombocytopenia. ITP is the result of accelerated platelet destruction by the reticuloendothelial system, primarily the spleen. The prevalence of Helicobacter pylori infection and the effect of its eradication were monitored in an ITP patient over a period of 12 months. Eradication of Helicobacter pylori led to the increased platelet count and provides a new insight for a non-immunosuppressive treatment in selective ITP patients.
Endovascular Treatment of Congenital Internal Carotid-Jugular Fistula
Authors: Ming Wang, Weijian Fan, Rajneesh Mungur, Jun Gu, Shu Wan
Journal: Front Neurol (2018)
Keywords: endovascular treatment, internal carotid artery, internal carotid-jugular fistula, jugular vein, stent
MeSH terms: Case Reports

A carotid-jugular fistula is a direct communication between the carotid artery and the jugular vein. Both congenital and spontaneous internal carotid-jugular fistulas are extremely rare. We describe the first case of successful endovascular treatment for a congenital internal carotid-jugular fistula. We report a 64-year-old woman who presented with a pulsatile mass swelling over the left cervical region and right hemiparesis after cough. Digital subtraction angiography confirmed the diagnosis of left high-flow internal carotid-jugular fistula. The fistula was successfully treated by fractional stent-assisted embolization.
Fatal fulminant hepatitis in a patient taking abiraterone acetate: a case report
Authors: Dela Akpokavie, Capucine Gubert, Imene Abdelli, Alix O'Meara Stern, Hervé Zender
Journal: Front Med (Lausanne) (2023)
Keywords: abiraterone, case report, fulminant hepatitis, hepatotoxicity, prostate cancer
MeSH terms: Case Reports

Abiraterone acetate is a steroidal inhibitor of cytochrome P450 17A1 indicated in the treatment of metastatic prostate cancer. This report examines the case of a 66-year-old patient diagnosed with prostate adenocarcinoma that had metastasized to the bones and lymph nodes. Treatment with abiraterone acetate and corticosteroid co-administration as well as LH-RH analog hormone therapy was initiated. Four and a half months later, the patient consulted for deterioration of general condition. Biologically, he developed a fulminant hepatitis of which he eventually died. An infectious or metabolic origin was ruled out. Oncological cause by either disease progression or second neoplastic process was eliminated by means of imaging. Hepatic toxicity was imputed to the treatment with abiraterone acetate. This case suggests that fulminant hepatitis on abiraterone acetate may be underestimated, and underscores the importance of regular monitoring of liver tests on this therapy.
Autologous Platelet-Rich Fibrin in the Treatment of Refractory Macular Holes
Authors: Arif Koytak, Fadime Nuhoglu, Havvanur Bayraktar, Rukiye Ercan, Hakan Ozdemir
Journal: Case Rep Ophthalmol Med (2019)
MeSH terms: Case Reports

Purpose:
To describe a novel method for the treatment of refractory macular holes.
Methods:
Two case reports on the use of autologous platelet rich fibrin (PRF), followed by sulfur hexafluoride gas tamponade to facilitate closure of refractory macular holes.
Results:
Macular holes were succesfully closed within a week in both cases. Best corrected Snellen visual acuities improved from counting fingers to 0.16 in the first case, and from 0.05 to 0.2 in the second case. No complication occurred during or after the procedures.
Conclusion:
The use of autologous PRF seems to be a safe and effective alternative method for the treatment of refractory macular holes. Further experience and studies are required to assess the value of autologous PRF in the management of challenging macular hole cases of different etiologies. To the best of our knowledge, this is the first use of autologous PRF in the treatment of macular holes.
Adenoid cystic carcinoma of the palate: case report and review of literature
Authors: Uday Shankar Yaga, Nishanth Gollamudi, Ashwini Kumar Mengji, Radhika Besta, Prashanth Panta, Bhanu Prakash, Edunuri Rajashekar
Journal: Pan Afr Med J (2016)
Keywords: cribriform variant, palate, perineural invasion, salivary gland
MeSH terms: Carcinoma, Adenoid Cystic / diagnosis, Palatal Neoplasms / diagnosis, Salivary Gland Neoplasms / diagnosis, Case Reports, Review, Adult, Carcinoma, Adenoid Cystic / pathology, Female, Head and Neck Neoplasms / diagnosis, Head and Neck Neoplasms / pathology, Humans, Palatal Neoplasms / pathology, Salivary Gland Neoplasms / pathology

Adenoid Cystic Carcinoma (ACC) is a rare tumor constitutes for less than 1% of head and neck malignancies and 10% of all salivary gland tumors. Palate is the most common site to be involved in the oral cavity followed by parotid gland and submandibular gland. They are usually asymptomatic, slow growing, characteristically shows infiltrative growth and perineural invasion. This paper reports a case of Adenoid Cystic Carcinoma in a 35 year old female man reported with a swelling on the left side of palate involving the hard and soft palate since 8 months which was diagnosed histopathologically and review of literature of the peculiar clinical, and histopathological features.
Management of Retrograde Peri-Implantitis Using an Air-Abrasive Device, Er,Cr:YSGG Laser, and Guided Bone Regeneration
Authors: Nikolaos Soldatos, Georgios E Romanos, Michelle Michaiel, Ali Sajadi, Nikola Angelov, Robin Weltman
Journal: Case Rep Dent (2018)
MeSH terms: Case Reports

Background:
The placement of an implant in a previously infected site is an important etiologic factor contributing to implant failure. The aim of this case report is to present the management of retrograde peri-implantitis (RPI) in a first maxillary molar site, 2 years after the implant placement. The RPI was treated using an air-abrasive device, Er,Cr:YSGG laser, and guided bone regeneration (GBR).
Case description:
A 65-year-old Caucasian male presented with a draining fistula associated with an implant at tooth #3. Tooth #3 revealed periapical radiolucency two years before the implant placement. Tooth #3 was extracted, and a ridge preservation procedure was performed followed by implant rehabilitation. A periapical radiograph (PA) showed lack of bone density around the implant apex. The site was decontaminated with an air-abrasive device and Er,Cr:YSGG laser, and GBR was performed. The patient was seen every two weeks until suture removal, followed by monthly visits for 12 months. The periapical X-rays, from 6 to 13 months postoperatively, showed increased bone density around the implant apex, with no signs of residual clinical or radiographic pathology and probing depths ≤4 mm.
Conclusions:
The etiology of RPI in this case was the placement of an implant in a previously infected site. The use of an air-abrasive device, Er,Cr:YSGG, and GBR was utilized to treat this case of RPI. The site was monitored for 13 months, and increased radiographic bone density was noted.
Clinical case: Differential diagnosis of idiopathic pulmonary fibrosis
Authors: Carlos Robalo Cordeiro, Tiago M Alfaro, Sara Freitas
Journal: BMC Res Notes (2013)
MeSH terms: Alveolitis, Extrinsic Allergic / pathology, Disease Management, Hypertension, Pulmonary / pathology, Idiopathic Pulmonary Fibrosis / pathology, Lung / pathology, Pulmonary Emphysema / pathology, Research Support, Non-U.S. Gov't, Acetylcysteine / therapeutic use, Alveolitis, Extrinsic Allergic / diagnosis, Alveolitis, Extrinsic Allergic / drug therapy, Azathioprine / therapeutic use, Diagnosis, Differential, Humans, Hypertension, Pulmonary / complications, Hypertension, Pulmonary / diagnosis, Hypertension, Pulmonary / drug therapy, Idiopathic Pulmonary Fibrosis / complications, Idiopathic Pulmonary Fibrosis / diagnosis, Idiopathic Pulmonary Fibrosis / drug therapy, Lung / diagnostic imaging, Male, Middle Aged, Prednisolone / therapeutic use, Pulmonary Emphysema / complications, Pulmonary Emphysema / diagnosis, Pulmonary Emphysema / drug therapy, Radiography, Smoking, Prednisolone, Azathioprine, Acetylcysteine

Background:
The diagnosis of idiopathic pulmonary fibrosis can be quite challenging, even after careful clinical evaluation, imaging and pathological tests. This case report intends to demonstrate and discuss these difficulties, especially those concerning the differential diagnosis with chronic hypersensitivity pneumonitis.
Case presentation:
A 58-year-old white male presented with shortness of breath, dry cough, fatigue and weight loss for two months. He was a former smoker and had regular exposure to a parakeet and poultry. Physical examination revealed bilateral basal crackles and chest imaging showed subpleural cystic lesions and traction bronchiectasis with a right side and upper level predominance. Auto-antibodies and IgG immunoglobulins to parakeet and fungal proteins were negative. Lung function tests displayed moderate restriction, low diffusion capacity and resting hypoxaemia. Bronchoalveolar lavage showed increased lymphocytes (28%) and neutrophils (12%) and surgical lung biopsy was compatible with a pattern of usual interstitial pneumonia. According to the possibility of either idiopathic pulmonary fibrosis or chronic hypersensitivity pneumonitis, treatment included prednisolone, azathioprine, acetylcysteine and avoidance of contact with the parakeet, but there was an unfavorable response and the patient was subsequently referred for lung transplant.
Conclusion:
Chronic hypersensitivity pneumonitis and idiopathic pulmonary fibrosis can present with the same clinical and radiological manifestations In this case, despite careful evaluation, no definite diagnosis could be achieved.