OpenMed/multicare-articles huggingface dataset:
Management of Spinal Bone Metastases With Radiofrequency Ablation, Vertebral Reinforcement and Transpedicular Fixation: A Retrospective Single-Center Case Series
Authors: Giuseppe Roberto Giammalva, Roberta Costanzo, Federica Paolini, Umberto Emanuele Benigno, Massimiliano Porzio, Lara Brunasso, Luigi Basile, Carlo Gulì, Maria Angela Pino, Rosa Maria Gerardi, Domenico Messina, Giuseppe Emmanuele Umana, Paolo Palmisciano, Gianluca Scalia, Francesca Graziano, Massimiliano Visocchi, Domenico Gerardo Iacopino, Rosario Maugeri
Journal: Front Oncol (2022)
Keywords: pmma, rfa, spinal fixation, spinal metastases, vertebral reinforcement

Spine is a frequent site of bone metastases, with a 8.5 months median survival time after diagnosis. In most cases treatment is only palliative. Several advanced techniques can ensure a better Quality of Life (QoL) and increase life expectancy. Radiofrequency ablation (RFA) uses alternating current to produce local heating and necrosis of the spinal lesion, preserving the healthy bone. RFA is supported by vertebral reinforcement through kyphoplasty and vertebroplasty in order to stabilize the fracture with polymethylmethacrylate (PMMA) injection, restoring vertebral body height and reducing the weakness of healthy bone. The aim of this study is to demonstrate the efficacy and advantages of RFA plus vertebral reinforcement through PMMA vertebroplasty and fixation in patients affected by bone spinal metastases. We retrospectively analyzed 54 patients with thoraco-lumbar metastatic vertebral fractures admitted to our Unit between January 2014 and June 2020. Each patient underwent RFA followed by PMMA vertebroplasty and transpedicle fixation. We evaluated pain relief through the Visual Analogue Scale (VAS) Score and PMMA vertebral filling based on the mean Saliou filling score. Analysis of variance (ANOVA) was used to test pain relief with statistical significance for p<0.05. A total of 54 patients (median age 63,44 years; range 34-86 years), with a total of 63 infiltrated vertebrae, were treated with RFA, PMMA vertebroplasty and transpedicular screw fixation; average operative time was 60.4 min (range 51-72). The preoperative average VAS score decreased significantly from 7.81 to 2.50 (p < 0.05) after 12 months. Based on Saliou filling score, filling was satisfactory (12-18) in 20 vertebrae (31,7%), mediocre (6-11) in 33 vertebrae (52,4%), inadequate (0-5) in 10 vertebrae (15,9%). A consistent PMMA filling of vertebral bodies was successfully achieved with significant pain relief. Concomitant RFA, PMMA vertebroplasty and pedicle screw fixation represent a safe and effective technique for the management of spinal metastases, improving clinical outcome and pain control.
Personal barriers to participation in chosen instrumental activities of daily living among community-dwelling persons with schizophrenia in Rwanda
Authors: Pierre D Turikumana, Lizahn G Cloete, Jerome P Fredericks
Journal: Afr J Disabil (2023)
Keywords: community participation, decreased motivation, individual hindrances, instrumental activities of daily living, medication side effect isolation, personal barriers, schizophrenia

Background:
Mental disorders are a major health concern across the globe. Schizophrenia, one of the mental disorders, affects approximately 20 million people globally and 5 million people within the African continent. Schizophrenia can affect all areas of life, including participation in instrumental activities of daily living (IADLs).
Objectives:
The study aimed to explore personal barriers affecting participation in chosen IADLs among community-dwelling persons with schizophrenia in Kigali city, Rwanda.
Method:
A qualitative, embedded case study design and constructivist epistemology paradigm were used. Purposive sampling and semi-structured interviews were conducted with 20 participants that included 10 persons diagnosed with schizophrenia (case 1) and 10 of their caregivers (case 2). Data were analysed according to the seven steps of Ziebland and Mcpherson.
Findings:
The two themes identified were community negative attitudes and individual hindrances to participation in IADLs. Theme 1 demonstrated the community's poor support towards persons with schizophrenia due to the stigma attached to mental health illness, which is reported elsewhere. This paper reports on individual hindrances to participation, which revealed limited knowledge and skills, decreased motivation and interest, financial problems, maladaptive behaviours, medication side effects, loss of social interaction and isolation, and disorganised in performing activities to negatively affect persons with schizophrenia's full participation in their chosen IADLs.
Conclusion:
Community-dwelling persons with schizophrenia are experiencing various hindrances to participating in their chosen IADLs, which shows a need for support from different stakeholders to improve access and participation of persons with schizophrenia in their daily activities based on their abilities.
Contribution:
Different barriers affecting participation of the persons with schizophrenia in their chosen IADLs were highlighted together with the common affected IADLs. It is recommended that when right support is provided, persons with schizophrenia may function at their maximum abilities in their activities of choice and may live at their highest independence level.
A Rare Case of Intracardiac Extension of Hepatocellular Carcinoma in a Child
Authors: Abdulrahman Al Jassmi, Hani Humad, Said Abou Eida
Journal: Case Rep Oncol Med (2019)
MeSH terms: Case Reports

Hepatocellular carcinoma (HCC) is the fifth most common malignancy found in men and ninth most common in women, out of which 72.5% reported cases are from Asia. In children, it accounts for <2% cases worldwide with even rarer incidence of 1.2% involving intracardial extension. However, it presents with a high mortality rate with mean survival ranging from 1 to 4 months. The present case is an extremely rare case of intracardiac extension of HCC in a 3.5-year-old Asian girl with no history of hepatitis B infection presented at an advanced stage of HCC who succumbed within one month of presentation to the hospital.
Malignant nerve sheath tumour of omentum and the "omental vascular pedicle sign"
Authors: Udit Chauhan, Alok Kumar Udiya, Shailesh M Prabhu, Gurucharan S Shetty
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

Primary malignant peripheral nerve sheath tumour (MPNST) is an uncommon malignant tumour that arises from the peripheral nerves. Most of these tumours arise in the regions of the trunk, head and neck, or extremities and are rarely seen in the abdomen. In this report, we describe a case of MPNST of the greater omentum, which, to the best of our knowledge, is only the second case reported in the literature. MPNST is an uncommon tumour that can show local invasion and has a high risk of recurrence. We also discuss the utility of "omental vascular pedicle sign" to help establish the omental origin of intra-abdominal masses.
Combined Surgical and Restorative Procedures to Treat Maxillary Canine with Gingival Recession and Cervical Wear
Authors: Dler Ali Khursheed, Faraedon Mostafa Zardawi
Journal: Case Rep Dent (2022)
MeSH terms: Case Reports

Introduction:
Gingival recession (GR) with cervical tooth wear is a major concern for patients on the prominent maxillary canines, from both esthetic and dentine hypersensitivity points of view. Hypersensitivity could be treated nonsurgically; however, esthetics remain the major patients' concern that mostly requires surgical intervention for covering the denuded root surface. Several surgical procedures are applied successfully for covering single and multiple gingival recession; however, these procedures are sensitive procedures and not always predictable. Semilunar coronally repositioned flap (SCRF) is a very simple procedure that found to be very predictable for covering a single recession in presence of sufficient keratinized gingiva apical to the recession. The procedure provides better clinical outcome by involving less adjacent papillary tissue that maintains greater blood supply and achieves maximum flap stability with mattress sutures with minimal postoperative complications. Therefore, this case report is aimed at explaining the simplicity of this surgical procedure in the presence of wide keratinized tissue around the recession and starting the restorative procedure after a sufficient soft tissue healing period. Case Presentation. 42-year-old systemically healthy female patient referred with a single wide gingival type 1 (RT1) and cervical wear around tooth #43. A semilunar coronally repositioned flap was released and advanced coronally to cover the denuded root totally; then, the flap stabilized by three mattress sutures, and complete root coverage was achieved. Six months later, the cervical lesion was restored with composite filling material. Sixteen-month and 32-month postoperative follow-up revealed full coverage of the denuded root surface with firm stable gingiva; later, the gingiva in the area looked stable and healthy.
Conclusion:
Using SCRF in treating RT1 recession in the presence of wide keratinized gingiva is very promising surgical intervention for receded root coverage that requires less technical skill.
Coronary thrombosis in a young male with COVID-19
Authors: Abdullah Shams, Fateen Ata, Kamran Mushtaq, Waqar Munir, Zohaib Yousaf
Journal: IDCases (2020)
Keywords: covid-19, myocardial infarction, sars-cov-2, thrombosis
MeSH terms: Case Reports

COVID-19 predominantly presents with respiratory symptoms, but other presentations are reported, including cardiac manifestations and thromboembolism. We present a healthy young gentleman with COVID-19 pneumonia, who developed acute ST-segment elevation myocardial infarction (STEMI) due to coronary thrombosis. He was managed successfully by primary percutaneous coronary intervention (PPCI).
High N Storage but Low N Recovery After Long-Term N-Fertilization in a Subtropical Cunninghamia lanceolata Plantation Ecosystem: A 14-Year Case Study
Authors: Fangfang Shen, Wenfei Liu, Honglang Duan, Jianping Wu, Chunsheng Wu, Yingchun Liao, Yinghong Yuan, Houbao Fan
Journal: Front Plant Sci (2022)
Keywords: cunninghamia lanceolata plantation, n storage, ecosystem components, long-term n fertilization, plant organs

Forests are among the most important N pools of all terrestrial ecosystems. Elevated atmospheric N deposition in recent decades has led to increased interest in the influences of N application on forest N cycles. However, accurate assessments of N storage in forest ecosystems remain elusive. We used a 14-year experiment of a Chinese fir [Cunninghamia lanceolata (Lamb.) Hook] plantation to explore how long-term N fertilization affected N storage and recovery rates. Our study plots were located in a field that had been continuously fertilized over 14 years (2004-2017) with urea at rates of 0 (N0, control), 60 (N60, low-N), 120 (N120, medium-N), and 240 (N240, high-N) kg N hm-2a-1. Data were collected that included N content and biomass in the understory, litter, and various plant organs (i.e., leaves, branches, stems, roots, and bark), as well as soil N content and density at different depths. Results showed that the total ecosystem N storage in the N-fertilized plots was 1.1-1.4 times higher than that in the control plots. About 12.36% of the total ecosystem N was stored in vegetation (plant organs, litter, and understory) and 87.64% was stored in soil (0-60 cm). Plant organs, litter, and soil had higher N storage than the understory layer. Significantly higher plant N uptake was found in the medium-N (1.2 times) and high-N (1.4 times) treatments relative to the control. The N recovery rate of the understory layer in the N-fertilized treatments was negative and less than that in the control. Application of long-term N fertilizer to this stand led to a low N recovery rate (average 11.39%) and high loss of N (average 91.86%), which indicate low N use efficiency in the Chinese fir plantation ecosystem. Our findings further clarify the distribution of N in an important terrestrial ecosystem and improve our understanding of regional N cycles.
The Possible Role of IVIG in the Treatment of Atrial Fibrillation Accompanied by Fulminant Myocarditis in a 12-Year-Old Pediatric Patient
Authors: Can Yilmaz Yozgat, Osman Yesilbas, Selcuk Uzuner, Nigar Bayramova, Gokce Ergun, Lala Nurmammadova, Eser Tekin, Hafize Otcu Temur, Yilmaz Yozgat
Journal: Case Rep Pediatr (2021)
MeSH terms: Case Reports

Background:
Fulminant myocarditis (FM) is a potentially lethal condition in children due to rapid progressive hemodynamic instability and cardiogenic shock. Patients with FM might show different clinical manifestations on emergency department admission.
Case:
Herein, we describe the case of a 12-year-old girl who was admitted to our institution's emergency department due to complaints of abdominal pain and incessant vomiting. However, we detected an early onset of atrial fibrillation (AF) accompanied by FM. The patient's condition of AF and severe hemodynamic disorder was successfully treated in our institution's pediatric intensive care unit.
Conclusion:
To the best of our knowledge, this is the first report of the co-occurrence of FM and AF successfully treated in childhood. This case report will serve as a guide for the treatment of cases with FM accompanied by AF.
Value-based requirements engineering: method and experience
Authors: Sarah Thew, Alistair Sutcliffe
Journal: Requir Eng (2018)
Keywords: emotions, motivations, requirements elicitation, values

'Socio-political' issues, such as emotions, values and people's feelings, are often cited as problems in the RE process. A method is described for analysing such issues. The method consists of a taxonomy of stakeholders' values, motivations and emotions (VME), with process guidance for eliciting and analysing these issues for the RE process and design implications. Values are personal attitudes or long-term beliefs which may influence stakeholder functional and non-functional requirements. Motivations are psychological constructs related to personality traits which may be viewed as stakeholders' long-term goals in RE. Emotions are cues to stakeholders' reactions arising from value/motivation conflicts. The method is supported by a website which illustrates the taxonomy with explanations and scenarios describing problems arising from value conflicts, and from poor understanding of stakeholder values. Two method validation studies were undertaken: first, an evaluation of the website and method by novices and RE experts; and second, case study applications of RE value analysis in real-world industrial practice. The method was used by all practitioners, although in different ways, some used it to create an agenda of issues for analysis while others employed the VMEs to interpret stakeholders' views and manage stakeholder negotiations. The validation studies provide evidence for the acceptability of the method for industrial practitioners, illustrating how value-related problems are identified and analysed effectively by the method. The utility of analysing VMEs is compared to other 'socio-political issues'-oriented methods in RE and methods which focus on monetized values in product requirements.
Gastric Outlet Obstruction and Sigmoid Volvulus in a Patient with Pneumatosis intestinalis: An Etiology or a Complication
Authors: Osama Shaheen, Wassim Ahmad, Najm Aldin Mhammad
Journal: Case Rep Surg (2019)
MeSH terms: Case Reports

Pneumatosis intestinalis (PI) is a radiographic finding which refers to the presence of gas within the wall of any part of the gastrointestinal tract. While in some cases it is an incidental finding which usually represent its benign nonischemic etiology, it may indicate a catastrophic intra-abdominal condition and distinctly characteristic of ischemic enterocolitis. Herein, we discuss the clinical signs and symptoms, the radiological features, the surgical management and outcome of an extremely rare concurrent triad of PI, gastric outlet obstruction, and the sigmoid volvulus based on a case of a patient who underwent surgery in our hospital, which, we think, can emphasize the mysterious concept of PI's mechanical etiology.
An Atypical Case of Oral Squamous Cell Carcinoma of Mandibular Alveolus
Authors: Seba Abraham, Bhagyalekshmi Mallika, Arunima Reshma, ReejaMol Mohammed Kassim
Journal: Case Rep Dent (2019)
MeSH terms: Case Reports

Oral squamous cell carcinoma is the most common type of oral malignant neoplasm. As per literature, squamous cell carcinomas of the alveolar ridge account for 9% of all the oral carcinomas. The oral squamous cell carcinoma shares clinical similarity with various forms of inflammatory gingival lesions and is often misdiagnosed in our routine dental practice. The dentist should have precise knowledge regarding the clinical manifestation of this deadly disease as early diagnosis and prompt treatment can reduce morbidity and mortality of the disease.
Osteosarcomatous Divergence in Dedifferentiated Liposarcoma Presenting as a Colonic Mass
Authors: Jeenal Gordhandas, Grace Lin, Ann M P Tipps, Somaye Y Zare
Journal: Case Rep Pathol (2019)
MeSH terms: Case Reports

Dedifferentiated liposarcomas most commonly arise in the retroperitoneum, accounting for 10% of liposarcomas. Heterologous differentiation occurs in 5-10% of dedifferentiated liposarcomas; however, divergent osteosarcomatous differentiation is rare. We report a rare case of initial presentation of dedifferentiated liposarcoma with osteosarcomatous component as a colonic mass in a 72-year-old man. The tumor is mainly composed of bony trabeculae with intervening highly atypical cells and adjacent high-grade mesenchymal nonlipogenic tumor, as well as areas of well-differentiated liposarcoma. Immunohistochemical studies showed diffuse positivity for SATB2 in the atypical cells and fluorescence in situ hybridization revealed high-level amplification of MDM2 gene, supporting the diagnosis of well-differentiated and dedifferentiated liposarcoma with heterologous osteosarcomatous differentiation.
Case Report: Improved surgical treatment for breast capsular contracture by the punctiform-incision approach through the nipple
Authors: Yan Zheng, Yan-Yan Hu, Wan-Yi Zhao, Xiao-Feng Wang, Qing-Qing Fang, Xiong Lv, Chun Xiang, Jian-Min Yao, Wei-Qiang Tan
Journal: Front Surg (2022)
Keywords: breast implants, capsular contraction release, innovative double-headed separator, nipple entry, punctiform incision
MeSH terms: Case Reports

Capsular contracture is one of the most common complications of breast implants, which often leads to secondary surgery. Patients with unconspicuous breast contracture do not need treatment, while for those with severe symptoms, a capsule revision surgery is of great necessity, including a total periprosthetic capsulectomy and replacement with a new implant. However, if the capsular contracture happens in the submuscular space, it will be very difficult to release it completely, and it may lead to more complications such as damage to surrounding tissue. The new method of pouch can create a new subpectoral plane for the insertion of a new implant instead of a total capsulectomy, but this method is unsuitable for patients who have little breast tissue or thin skin. To solve this thorny clinical problem, we invented a double-headed separating instrument and came up with a novel operation method to release the capsular contracture, which opened from the nipple by the punctiform-incision approach and caused only a mild and undetectable trauma. This operation went off without a hitch, and the postoperative breast shape was good, and the breast felt and moved naturally. In addition, there were no significant complications throughout the one-year follow-up period. This case was an excellent demonstration of the novel breast capsular contracture release surgery using our optimized double-headed capsule contracture separator.
A regimen of taxol, Ifosfamide, and platinum for recurrent advanced squamous cell cancer of the anal canal
Authors: Diana V Golub, A Cahid Civelek, Vivek R Sharma
Journal: Chemother Res Pract (2011)
MeSH terms: Case Reports

The typically recommended chemotherapy options in metastatic anal cancer generally yield partial remissions with limited benefit for the majority of patients. TIP is a regimen containing paclitaxel (Taxol), ifosfamide, and cisplatin that is known to have significant activity in patients with squamous cell cancers of the head and neck as well as in cervical cancer, both of which are malignancies strongly associated with oncogenic strains of human papilloma virus (HPV). Interestingly, squamous cell cancer of the anal canal shares an almost identical pathophysiology including causal association with HPV. Due to this, we chose to use the TIP regimen to treat patients with advanced anal cancer at our institution and report our findings on three such consecutive patients. All the patients tolerated the regimen well with manageable side effects and had excellent responses with complete resolution of PET activity after treatment. Our observations suggest that TIP is highly active for squamous cell cancer of the anal canal and warrants further study in the treatment of this disease.
A Logic-Based Psychotherapy Approach to Treating Patients Which Focuses on Faultless Logical Functioning: A Case Study Method
Authors: Fernando Almeida, Diana Moreira
Journal: Front Psychol (2017)
Keywords: behavior modification, case study, cognitive bias, interpersonal relationship, logic-based psychotherapy, logical reasoning/functioning

Many clinical patients present to mental health clinics with depressive symptoms, anxiety, psychosomatic complaints, and sleeping problems. These symptoms which originated may originate from marital problems, conflictual interpersonal relationships, problems in securing work, and housing issues, among many others. These issues might interfere which underlie the difficulties that with the ability of the patients face in maintaining faultless logical reasoning (FLR) and faultless logical functioning (FLF). FLR implies to assess correctly premises, rules, and conclusions. And FLF implies assessing not only FLR, but also the circumstances, life experience, personality, events that validate a conclusion. Almost always, the symptomatology is accompanied by intense emotional changes. Clinical experience shows that a logic-based psychotherapy (LBP) approach is not practiced, and that therapists' resort to psychopharmacotherapy or other types of psychotherapeutic approaches that are not focused on logical reasoning and, especially, logical functioning. Because of this, patients do not learn to overcome their reasoning and functioning errors. The aim of this work was to investigate how LBP works to improve the patients' ability to think and function in a faultless logical way. This work describes the case studies of three patients. For this purpose we described the treatment of three patients. With this psychotherapeutic approach, patients gain knowledge that can then be applied not only to the issues that led them to the consultation, but also to other problems they have experienced, thus creating a learning experience and helping to prevent such patients from becoming involved in similar problematic situations. This highlights that LBP is a way of treating symptoms that interfere on some level with daily functioning. This psychotherapeutic approach is relevant for improving patients' quality of life, and it fills a gap in the literature by describing original case analyses.