OpenMed/multicare-articles huggingface dataset:
Occipitocervical Hemolymphangioma in an Adult with Neck Pain and Stiffness: Case Report and Literature Review
Authors: Yongchao Li, Xing Zhang, Xiaodong Pang, Liang Yang, Baogan Peng
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

Introduction:
Hemolymphangioma is an extremely rare malformation of the lymphatic and blood vessels. A limited number of hemolymphangioma cases occurring in the pancreas, extremities, spleen, and other organs have been reported until September 2017. To the best of our knowledge, no cases of hemolymphangioma in the occipitocervical region have been reported in the literature.
Case presentation:
We reported the case of a 23-year-old male patient with an occipitocervical lesion presenting atypically as neck pain and stiffness over a period of five months. Although hemolymphangioma has historically demonstrated a female predilection (2.25 : 1 female to male) and presentation in the third to fourth decades of life, this case is an atypical manifestation occurring in a young male patient. The clinical characteristics and management choices of this uncommon case of hemolymphangioma in the occipitocervical region are discussed, and a review based on the available literature is also presented.
Conclusion:
Hemolymphangioma of the occipitocervical region is an uncommon presentation of a rare lesion. Although rare, hemolymphangioma should be considered a differential diagnosis for masses occurring in the occipitocervical region. Complete surgical resection is the treatment of choice and affords a good prognosis.
Tetrodotoxin Poisoning Due to Pufferfish Ingestion in the United Arab Emirates
Authors: Zahra K Al Dhuhaibat, Talal Zarzour
Journal: Cureus (2023)
Keywords: emergency medicine, neurotoxic, poisoning of pufferfish, swellfish, tetrodotoxin, toxicology
MeSH terms: Case Reports

Tetrodotoxin is a potent neurotoxin that is found in the ovaries and liver of pufferfish. This lethal toxin is heat stable and does not destroy by cooking that is why precaution should be taken when eating pufferfish. A 60-year-old male presented to the ED after eating pufferfish complaining of perioral and hand numbness, gait disturbance, and generalized body weakness. This presentation is due to a tetrodotoxin found in and not limited to the pufferfish he ingested. Despite having pufferfish with his family, he was the sole person to have symptoms because, unlike the other family members, he ate from the liver part of the fish. The patient was admitted for observation, received supportive care, and underwent multiple investigations that most came to be normal. He improved gradually and was discharged after staying for three nights in the hospital. Symptoms after eating the toxic parts of a pufferfish may progress to paralysis, and respiratory failure, and may lead to death. It is not common to have such fish eaten in the United Arab Emirates due to its limited availability.
Postvaccination Influenza 2009 H1N1 Respiratory Failure Requiring Extracorporeal Membrane Oxygenation
Authors: Michael S Firstenberg, Erik Abel, Danielle Blais, Juan Crestanello, Julie E Mangino
Journal: Case Rep Infect Dis (2011)
MeSH terms: Case Reports

The spread of pandemic Influenza A (H1N1-2009) was believed to have been attenuated by the effectiveness of worldwide vaccination initiatives. Despite the immunogenicity of a safe vaccine, we report a case of vaccine failure resulting in catastrophic influenza-associated respiratory failure.
Exacerbating Guillain-Barré Syndrome Eight Days after Vector-Based COVID-19 Vaccination
Authors: Josef Finsterer
Journal: Case Rep Infect Dis (2021)
MeSH terms: Case Reports

Since the introduction of mRNA technology-based and vector-based COVID-19 vaccines, adverse reactions to these agents have been occasionally reported. Exacerbation of Guillain-Barré syndrome (GBS) shortly after COVID-19 vaccination has not been communicated. The patient is a 32-year-old male who developed progressive sensory disturbances and muscle weakness 8 days after the first dosage of a vector-based vaccine. Cerebrospinal fluid investigations revealed a dissociation cyto-albuminque, and nerve conduction studies revealed demyelination. Intravenous immunoglobulin (IVIG) exhibited only a marginal effect for both sensory and motor deficits. The patient's history was moreover positive for previous GBS with marked motor deficits 14 years earlier, which responded favourably to IVIG leading to almost complete recovery within 9 months of rehabilitation. Although apparently extremely rare, neurologists should remain vigilant for a potential recurrence of GBS after vaccination with a vector-based COVID-19 vaccine.
Unilateral heliotrope rash in juvenile dermatomyositis: an unusual presentation of an underlying serious disease
Authors: Ghada Al-Janobi, Hisham Alkhalidi, Mohammed A Omair
Journal: Case Rep Rheumatol (2014)

Background. Heliotrope rash is one of the characteristic skin manifestations of juvenile dermatomyositis. It is a reddish-purple rash on the upper eyelids that is usually bilateral. Case Presentation. We report a boy who presented with unilateral heliotrope rash, Gottron's papules, and muscle weakness. Muscle biopsy was consistent with inflammatory myositis. Patient was started on prednisolone and methotrexate with an excellent response in both the skin and muscles. Conclusion. Unilateral heliotrope rash can occur in patients with juvenile dermatomyositis. Being a paraneoplastic condition caution should be taken not to miss any underlying malignancy.
Hypervascular nodule in a fibrotic liver overloaded with iron: identification of a premalignant area with preserved liver architecture
Authors: António Sá Cunha, Jean-Frédéric Blanc, Hervé Trillaud, Victor De Ledinghen, Charles Balabaud, Paulette Bioulac-Sage
Journal: Comp Hepatol (2005)

BACKGROUND: The presence of a hypervascular nodule in a patient with cirrhosis is highly suggestive of a hepatocellular carcinoma. CASE PRESENTATION: A 55 year old man with idiopathic refractory anaemia was addressed for the cure of a recently appeared 3.3 cm hypervascular liver nodule. The nodule was not visible on the resected fresh specimen, but a paler zone was seen after formalin fixation. The surrounding liver was fibrotic (METAVIR score F3) and overloaded with iron. However, the paler zone, thought to be the nodule, had in fact a normal architecture, was less fibrotic, and contained some "portal tract-like structures" (but with arteries only); moreover, this paler area was devoid of iron, contained less glycogen and was characterized by foci of clear hepatocytes. CONCLUSION: In spite of the absence of architectural distortion, and a normal proliferative index, the possibility of premalignancy or malignancy should be considered in this type of hypervascular and hyposiderotic nodule, occurring in the context of an iron overloaded liver.
Pulmonary Sarcoidosis following Etanercept Treatment for Ankylosing Spondylitis: A Case Report and Review of the Literature
Authors: A Majjad, A Bezza, A Biyi, M R El Ochi, A El Maghraoui
Journal: Case Rep Rheumatol (2018)
MeSH terms: Case Reports

Antitumor necrosis factor therapies have revolutionized the treatment of some inflammatory diseases. However, the use of these agents is associated with the development of many paradoxical autoimmune diseases. Less well-recognized is the association with sarcoidosis. We report a 55-year-old female with long-standing ankylosing spondylitis who developed persistent dry cough and dyspnea while receiving etanercept therapy. High-resolution computed tomography scanning showed mediastinal lymphadenopathy and multiple nodules in both lung fields developed two months after the administration of etanercept. Lymph node biopsy was not practicable. Histopathological examination of minor salivary gland biopsy revealed noncaseating granulomata, and the serum angiotensin-converting enzyme was very elevated. All infectious studies were negative. Etanercept was discontinued plus a course of corticosteroids with a clinical improvement, and a follow-up high-resolution computed tomography scanning 4 months later showed evident regression of mediastinal lymph nodes and pulmonary nodules. Potential pathogenic mechanisms of this paradoxical effect of tumor necrosis factor-alpha blocking agents are discussed.
Imaging appearance of a post-intubation cricoid chondronecrosis
Authors: Kavitha Palled, Venkatraman Bhat, Suhel Hassan, Maneesh Ganamukhi
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

Chondronecrosis is a known complication of external beam radiation therapy and endotracheal intubation. Radiation therapy is the most common cause of chondronecrosis owing to local cartilage ischaemia following treatment. Prolonged endotracheal intubation can lead to chondronecrosis as it is associated with excessive pressure on the cartilage by the endotracheal tube or its cuff. The cricoid ring is the most commonly affected cartilage. CT imaging is an integral part of the workup, although reports on imaging appearances are scant. We report the imaging and clinical presentation of a case of chondronecrosis secondary to the use of endotracheal tube ventilation. The patient was managed conservatively with good clinical outcome.
Endovascular treatment of an aneurysm associated with fenestration of the supraclinoid internal carotid artery: Case report and review of the literature
Authors: Rareṣ Cristian Filep, Cristian Constantin, Emil Marian Arbǎnaṣi, Adrian Vasile Mureṣan, Eliza Russu, Lucian Mǎrginean
Journal: Front Neurol (2022)
Keywords: endovascular, fenestration, internal carotid artery, intracranial aneurysms, neuroradiology
MeSH terms: Case Reports

Background:
Fenestrations or divisions of the vascular lumen into separate channels appear to be common anatomical variations in patients with intracranial aneurysms. The most frequent sites of occurrence are the anterior communicating artery (ACom), followed by vertebrobasilar and middle cerebral artery (MCA) locations.
Case presentation:
A 61-year-old female was brought to the emergency department after experiencing severe headache with abrupt onset, nausea, and vomiting. Clinical examination on arrival showed a drowsy patient (GCS 14), with neck stiffness, but no cranial nerve palsies or other neurological deficits (Hunt-Hess 2). Non-contrast head CT and CT angiography revealed subarachnoid and intraventricular hemorrhage (modified Fisher 4) and two saccular aneurysms, one located on the right supraclinoid ICA with peripheral calcifications, measuring 20 × 12 mm, the second on the left MCA bifurcation, 6 × 4 mm. 3D rotational angiography revealed a right ICA fenestration located between the ophthalmic (OA) and posterior communicating artery (PCom). The proximal part of the fenestration harbored a large saccular aneurysm projecting superiorly with the neck engulfing the origin of the fenestration; due to the favorable neck and geometry of the aneurysm, endovascular coil occlusion was chosen as a treatment option without balloon or stent assistance. The decision was taken to clip the MCA aneurysm.
Conclusion:
Supraclinoid ICA fenestrations are rare anatomical variations. Endovascular treatment of supraclinoid ICA fenestration-related aneurysms is feasible and safe, with the notable concern of perforators originating from the limbs.
Acute abdomen caused by ingested chicken wishbone: a case report
Authors: Faton T Hoxha, Shemsedin I Hashani, Driton S Komoni, Lumturije H Gashi-Luci, Fisnik I Kurshumliu, Medita Sh Hashimi, Avdyl S Krasniqi
Journal: Cases J (2009)

Introduction:
An ingested foreign body often passes the gastrointestinal tract without any complications. Foreign bodies, such as dentures, fish bones, chicken bones, and toothpicks, have been known to cause perforation of the GI tract.
Case presentation:
We are presenting a case of a fifty-year-old male with acute abdomen; diffuse fibro purulent peritonitis, i.e. ileum perforation, caused by accidentally ingesting a chicken wishbone. He was treated surgically with ileum resection, and temporary ileostomy. After four months, intestinal continuity was established in the second operation.
Conclusion:
Intestinal perforation by a chicken bone is rare and affects the left colon or distal ileum. The lack of information of ingestion and detection of chicken bones preoperatively are of interest to be considered in the differential diagnosis of acute abdomen, which in this case was treated surgically.
Nivolumab-Induced Encephalitis in Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome
Authors: Benjamin Chaucer, Abriella Stone, Augustus Demanes, Shawn M Seibert
Journal: Case Rep Oncol Med (2018)
MeSH terms: Case Reports

The treatment of cancer is a rapidly evolving field. As more chemotherapeutic agents become available, reporting the side effects of these agents in clinical practice becomes increasingly important. Nivolumab is one of the chemotherapeutic agents commonly used for treatment of renal cell carcinoma, metastatic melanoma, and metastatic non-small cell lung cancer. While common side effects are known and well documented, encephalitis is documented as an extremely rare side effect. We present the case of an extremely rare side effect to a common chemotherapeutic agent.
Rectal metastases from squamous cell carcinoma: a case report and review of the literature
Authors: S Cedrés, N Mulet-Margalef, M A Montero, P Martinez, A Martínez, E Felip
Journal: Case Rep Med (2012)
MeSH terms: Case Reports

Non-small-cell lung cancer (NSCLC) represents 85% of lung cancer. The most frequent sites of distant metastasis are the liver, adrenal glands, bones and brain. Gastrointestinal metastases are uncommon and rectal metastases are extremely rare. Here we report a case of squamous cell carcinoma of the lung with rectal metastases.
Assessment of Musculoskeletal Injuries from Domestic Violence in the Emergency Department
Authors: Georgios F Giannakopoulos, Udo J L Reijnders
Journal: Case Rep Emerg Med (2015)

Domestic violence is one of the most common causes of nonfatal injury in women, with musculoskeletal injuries representing the second most prevalent manifestation of this form of violence. It is therefore of great importance that healthcare providers such as emergency department (ED) physicians and surgeons are able to recognize and assess these kinds of injuries. In this case report, a woman is described visiting an ED with injuries caused by a fall. Thanks to the knowledge and attention of the ED physician, the real cause of the injury was discovered. What appeared to be an unsuspicious accident was actually the result of intimate partner violence.
Collagenofibrotic glomerulopathy - Case report with review of literature
Authors: K C Patro, R Jha, M Sahay, G Swarnalatha
Journal: Indian J Nephrol (2011)
Keywords: collagenofibrotic glomerulopathy, asymptomatic proteinuria, fibrillary material, fibrils
MeSH terms: Case Reports

Collagenofibrotic glomerulopathy is a rare, idiopathic glomerular disease characterized by abnormal accumulation of type III collagen fibrils within the mesangial matrix and subendothelial space and a marked increase in serum type III procollagen peptide levels. Proteinuria (commonest feature), edema, hypertension, and occasional progression to end-stage renal disease are the various features of this disease. The etiology and pathogenesis remain elusive. There have been reports of the disease running in the family, suggesting the possibility of genetic transmission. We report two cases of this rare entity.
Case Report: Cariprazine Efficacy in Young Patients Diagnosed With Schizophrenia With Predominantly Negative Symptoms
Authors: Octavian Vasiliu
Journal: Front Psychiatry (2021)
Keywords: cariprazine, negative symptoms, novel atypical antipsychotics, quality of life, schizophrenia, social reintegration, tolerability
MeSH terms: Case Reports

Negative symptoms of schizophrenia are among the most invalidating clinical manifestations of this disorder, and they are correlated with poorer prognosis, lower quality of life, and fewer chances for successful social reintegration and professional rehabilitation. Although atypical antipsychotics have been associated with higher efficacy on negative symptoms than typical agents, not all of them are equally effective. Cariprazine is a new D3 and D2 receptor partial agonist, and its high D3 affinity may be useful for decreasing several adverse events (e.g., extrapyramidal symptoms or hyperprolactinemia), and also for increasing this drug's efficacy over negative symptoms. This case series presents three young adults with predominantly negative symptoms during treatment with an atypical antipsychotic, administered in stable dose within the therapeutic range, and for at least 4 weeks prior to the cariprazine switch. These patients (two male and one female, mean age 35.7 years) were diagnosed with schizophrenia, according to the DSM-5 criteria. They were evaluated using Positive and Negative Syndrome Scale (PANSS), Clinical Global Impression-Severity (CGI-S), and Global Assessment of Functioning (GAF). Their mean initial values were 80.3 on PANSS, 4.3 on CGI-S, and 48 on GAF. All these patients were already on a treatment with stable doses of atypical antipsychotics (olanzapine 10 mg/day, n = 1, risperidone 6 mg/day, n = 1, and quetiapine 600 mg/day, n = 1). Cross-titration to cariprazine was initiated, from 1.5 mg qd up to 6 mg qd, during a mean period of 2.7 weeks. After 12 weeks of cariprazine 6 mg/day, the positive scale of PANSS was relatively stable compared to baseline, while the negative mean score decreased by 22%. Also, the mean CGI-S improvement was 15.4% and the GAF mean score increased by 17%. The overall tolerability was good, without severe adverse events being reported. Conclusions: Cariprazine is well tolerated and efficient for patients diagnosed with schizophrenia who have significant negative symptoms that impair daily functioning. After 12 weeks cariprazine succeeded in improving negative symptoms, global functioning, and clinical global impression.
Postoperative visual loss following cerebral arteriovenous malformation surgery: a case report
Authors: Nicolai Goettel, Jayati Ghosh, Michael Tymianski, Pirjo H Manninen
Journal: F1000Res (2014)

We report the case of a 46 year-old woman presenting with unilateral postoperative visual loss after right frontal craniotomy for resection of an arteriovenous malformation in the supine position. The intraoperative course was uneventful with maintenance of hemodynamic stability. Blood loss was 300 ml; postoperative hemoglobin was 12.4 g/dl. In the recovery room, the patient reported loss of vision in her right eye. Ophthalmologic examination revealed decreased visual acuity, color vision, and visual field. Assessment of the retina was normal, but the patient showed a relative afferent pupillary defect consistent with the clinical diagnosis of ischemic optic neuropathy. Postoperative computer tomogram showed normal perfusion of ophthalmic artery and vein, no hemorrhage or signs of cerebral ischemia or edema. The patient recovered most of her vision 3 months after surgery. Anesthesiologists should be aware that this condition may follow uncomplicated intracranial surgeries in the supine position, and should obtain prompt ophthalmologic consultation when a patient develops postoperative visual loss.
Pulsatile Proptosis due to Intraorbital Meningocele
Authors: Anouke van Rumund, Aad Verrips, Wim I M Verhagen
Journal: Front Neurol (2017)
Keywords: mri imaging, meningocele, orbital roof fracture, proptosis, pulsations
MeSH terms: Case Reports

We present a case of a 79-year-old man with a non-symptomatic pulsatile proptosis of the left eye. Magnetic resonance imaging revealed a meningocele into the left orbit due to an osseous defect in the orbital roof.
Malignant Hypertension Causing a Pulmonary-Renal Syndrome
Authors: Bryan Yong, David A Power
Journal: Case Rep Nephrol (2018)
MeSH terms: Case Reports

Background:
Pulmonary-renal syndrome is characterised by acute kidney injury, haematuria, and haemoptysis and is a well-recognised presentation of diseases such as ANCA vasculitis that require urgent immunosuppression.
Case presentation:
A patient presented with a brief history of haemoptysis, acute renal failure, microscopic haematuria, and severe hypertension. The diagnosis was initially not clear so he was treated with antihypertensives, renal replacement therapy, and immunosuppression. Renal biopsy subsequently showed evidence of malignant hypertension. Autoantibodies were uniformly negative.
Conclusions:
This case demonstrates that malignant hypertension can present as pulmonary-renal syndrome.
Pigmented nodular Basal cell carcinomas in differential diagnosis with nodular melanomas: confocal microscopy as a reliable tool for in vivo histologic diagnosis
Authors: Alice Casari, Giovanni Pellacani, Stefania Seidenari, Anna Maria Cesinaro, Francesca Beretti, Patrizia Pepe, Caterina Longo
Journal: J Skin Cancer (2011)
MeSH terms: Case Reports

Nodular basal cell carcinoma, especially when pigmented, can be in differential diagnosis with nodular melanomas, clinically and dermoscopically. Reflectance confocal microscopy is a relatively new imaging technique that permits to evaluate in vivo skin tumors with a nearly histological resolution. Here, we present four cases of challenging nodular lesions where confocal microscopy was able to clarify the diagnosis.
Right Transverse Testicular Ectopia: A Nonclassified Variant Confirmed on Laparoscopy
Authors: Landry Mbouché, E Njuma Tamufor, K G Fossi, A S Salihou, D E C Dikongue, Salihou Fadi, Bienvenu Binwe, F F Mouafo Tambo
Journal: Case Rep Urol (2021)
MeSH terms: Case Reports

Transverse testicular ectopia is a rare anomaly characterized by testicular descent into the scrotum through the same inguinal canal. Here, we report the case of a 15-year-old boy diagnosed with transverse testicular ectopia wherein both testes descended through separate inguinal canals. He underwent a diagnostic laparoscopy which helped to identify both spermatic cords entering both inguinal canals separately. During scrotal exploration, both testes were found in the same side. Transseptal orchidopexy was performed. The short-term follow-up is uneventful.
Primary hepaticobiliary tuberculosis mimicking gall bladder carcinoma with liver invasion: a case report
Authors: Muhammad Manzoor Ul Haque, Rajesh Kumar Whadva, Nasir Hassan Luck, Muhammed Mubarak
Journal: Pan Afr Med J (2019)
Keywords: carcinoma, frozen section, gall bladder, liver biopsy, tuberculosis
MeSH terms: Antitubercular Agents / therapeutic use, Liver Neoplasms / diagnosis, Tuberculosis, Hepatic / diagnosis, Case Reports, Abdominal Pain / etiology, Diagnosis, Differential, Gallbladder Neoplasms / diagnosis, Humans, Male, Middle Aged, Tuberculosis, Hepatic / drug therapy, Weight Loss, Antitubercular Agents

Primary hepatic tuberculosis is a rare presentation and sporadically reported in the literature, mostly from our part of the world. Sometimes the presentation can be atypical and mimics hepatic tumor and poses diagnostic challenge. We, herein, present a case of a 58-year-old man who presented to us with abdominal pain and weight loss. Raised serum alkaline phosphatase (ALP) and imaging raised a suspicion of gall bladder carcinoma with hepatic invasion. Peroperative frozen section revealed hepatic chronic granulomatous inflammation with caseous necrosis consistent with the diagnosis of hepatic tuberculosis. Surgery was postponed and he was put on antituberculous treatment. It is important to consider tuberculosis in the differential diagnosis of the space occupying lesion of liver in a patient with vague symptoms and abnormal findings on imaging.