OpenMed/multicare-articles huggingface dataset:
Pulsed Electromagnetic Field Therapy as a Complementary Alternative for Chronic Pelvic Pain Management in an Interstitial Cystitis/Bladder Pain Syndrome Patient
Authors: Tyler L Overholt, Christina Ross, Robert J Evans, Stephen J Walker
Journal: Case Rep Urol (2019)
MeSH terms: Case Reports

Interstitial cystitis/bladder pain syndrome is a chronic pelvic pain condition with no known etiology that affects millions of women and men in the United States. Current management can be aggressive for individuals who are refractory to less invasive options, often resulting in the use of opioid narcotics and/or surgical procedures under general anesthesia, with higher risks and side effects to patients. Pulsed electromagnetic field therapy is a noninvasive therapeutic strategy that is thought to reduce inflammation and pain via alteration of cellular function and microcirculation. This therapy has demonstrated efficacy in management of other chronic pain syndromes including fibromyalgia and chronic low back pain. Herein, we describe a case of pulsed electromagnetic field therapy for management of interstitial cystitis/bladder pain syndrome that resulted in decreases in pelvic pain, burning with bladder filling, and other nonpelvic pain symptoms. This case provides support for a formal clinical trial to evaluate the efficacy of pulsed electromagnetic field therapy for the management of chronic pelvic pain in interstitial cystitis/bladder pain syndrome.
Report on influenza A and B viruses: their coinfection in a Saudi leukemia patient
Authors: Fahad N Almajhdi, Ghazanfar Ali
Journal: Biomed Res Int (2013)
MeSH terms: Coinfection / complications, Coinfection / virology, Influenza, Human / complications, Influenzavirus A / physiology, Influenzavirus B / physiology, Leukemia / complications, Leukemia / virology, Case Reports, Research Support, Non-U.S. Gov't, Ethidium / metabolism, Female, Humans, Infant, Influenza, Human / virology, Saudi Arabia, Ethidium

Purpose:
Influenza A and B viruses are the leading cause of respiratory infections in children worldwide, particularly in developing countries. There is a lack of data on coinfection of influenza A and B viruses circulating in Saudi Arabia. In this study, we aimed to identify the circulation of influenza viruses that contribute to respiratory tract infections in Saudi children.
Methods:
We collected 80 nasopharyngeal aspirates (NPAs) from hospitalized children with acute respiratory illness (ARI) at Riyadh during the period extended from October 2010 till April 2011. Samples were tested for the common respiratory viruses including influenza viruses by RT-PCR.
Results:
Overall, 6 samples were found positive for influenza A and/or B viruses. Among these positive clinical samples, only one collected sample from a female one-year-old immunocompromised child with leukemia showed a coinfection with influenza A and B viruses. In present study coinfection was confirmed by inoculation of the clinical specimen in specific pathogenfree embryonating chicken eggs and identification of the virus isolates by hemagglutination and one-step RT-PCR.
Conclusion:
This study opens the scene for studying the role of influenza virus's coinfection in disease severity and virus evolution. Further studies are required to better understand the clinical importance of viral coinfection.
Comprehensive assessment of intelligent unmanned vehicle techniques in pesticide application: A case study in pear orchard
Authors: Yulin Jiang, Xiongkui He, Jianli Song, Yajia Liu, Changling Wang, Tian Li, Peng Qi, Congwei Yu, Fu Chen
Journal: Front Plant Sci (2022)
Keywords: uav, ugv, application performance, ecological assessment, orchard, plant protection

The intelligent pesticide application techniques in orchards have grown rapidly worldwide due to the decrease in agricultural populations and the increase in labor costs. However, whether and how intelligent pesticide application techniques are better than conventional pesticide application remains unclear. Here, we evaluated the performance of the unmanned aircraft vehicle (UAV) and unmanned ground vehicle (UGV) on pesticide application, ecological environment protection, and human's health protection compared to conventional manual methods. We quantified characteristics from the aspects of working effectiveness, efficiency, environmental pollution, water saving and carbon dioxide reduction. The results showed that the UAV application has the advantages of a higher working efficiency and less environmental pollution and natural resource consumption compared to the UGV and conventional manual methods despite of its worse spray performance The UGV application techniques could improve spray performance at the cost of high environmental pollution. The conventional spray gun technique was unfriendly to environmental and resource protection although it showed a better spray performance. Thus, the balance of improving spray performance and controlling environmental pollution is the key to improve the performance of UAV and UGV technology in the future. The study could be useful in the development of intelligent pesticide application techniques and provide scientific support for the transition of intelligent management in orchards.
A rare gas-containing lumbar synovial cyst treated by percutaneous transforaminal endoscopic cystectomy: A case report and literature review
Authors: Ziran Wei, Qian Lin, Hao Zhang, Haoyun Zhang, Xuexiao Ma, Chao Wang
Journal: Front Surg (2023)
Keywords: cystectomy, endoscopic surgery, gas, synovial cyst, vacuum cleft
MeSH terms: Case Reports

Spinal synovial cysts are rare entities for which standard surgical strategies are inconsistent. Here, we present an uncommon intraspinal gas-containing synovial cyst treated by percutaneous transforaminal endoscopic cystectomy. A 52-year-old man presented with radicular pain and intermittent claudication that had persisted for one month. Computed tomography revealed an intraspinal cystic lesion anteromedial to the left L4-L5 articular joint and the center of the lesion manifested gas contents. A transforaminal endoscopic procedure was performed and confirmed as a safe and minimally invasive technique for gas-containing lumbar synovial cysts. It provides a valuable substitution and supplementation to open surgery.
A New Method of Treatment of Temporomandibular Joint Ankylosis with Osteodistraction Using the Sh-Device: A Case Report
Authors: Gholamreza Shirani, Mahnaz Arshad, Xaniar Mahmoudi
Journal: J Dent (Tehran) (2018)
Keywords: bone lengthening, distraction osteogenesis, temporomandibular ankylosis, tissue expansion, treatment outcome
MeSH terms: Case Reports

This case report presents a 16-year-old boy with bilateral temporomandibular joint (TMJ) bony ankylosis due to trauma. The patient had undergone several unsuccessful therapeutic surgeries and was experiencing reduced mouth opening, difficulty in eating and speaking, poor oral hygiene, snoring, and depression. Bilateral gap arthroplasty and distraction osteogenesis (DO) were performed. After the surgery, we were able to move the osteodistractors forward and prevent the upward and backward movement of the proximal mandibular segment with the use of our custom-made Sh-device, which allowed bone growth and soft-tissue matching. The mandibular deficiency was treated, and the patient's sleep quality significantly improved after three months. The physical, orthodontic and speech therapies were continued. The facial asymmetry, difficulty in sleeping, eating and speaking, and low self-esteem were completely resolved. At the 8-year follow-up, the patient's condition was satisfactory. The Sh-device can be used as a contemporary treatment modality for TMJ ankylosis.
Pseudomonas aeruginosa Scleritis following Pterygium Surgery with Mitomycin C or Beta Irradiation: Three-Case Report
Authors: Winai Chaidaroon, Somsanguan Ausayakhun, Napaporn Tananuvat, Phit Upaphong, Kittipong Thabsuwan
Journal: Case Rep Ophthalmol Med (2022)
MeSH terms: Case Reports

Purpose:
To report three cases of culture-positive Pseudomonas aeruginosa scleritis following pterygium surgery. Patients and Methods. A retrospective study of all patients of Pseudomonas aeruginosa scleritis after pterygium surgery presented from May 2017 to May 2020 was performed. Patient demographics and clinical characteristics included age, gender, time between prior surgery and onset, adjunctive therapy, risk factors, initial visual acuity, final visual acuity, clinical features, medical treatment, and surgical intervention were analyzed.
Results:
Three eyes of three patients with clinical characteristics and laboratory-confirmed Pseudomonas aeruginosa scleritis were identified. Two patients were related with mitomycin C application after pterygium surgery, and only one had beta irradiation. Antibiotic administration and scleral debridement were required in 3 patients. One eye was enucleated. Final visual outcomes of two patients were improved.
Conclusions:

Pseudomonas aeruginosa scleritis after pterygium surgery is a crucial ophthalmic disease. An early diagnosis with a prompt intensive antibiotic treatment in combination with surgical interventions may improve visual outcome.
Gastric Antral Diverticula: A Rare Diverticula with a Unique Presentation
Authors: Pratishtha Singh, Kathleen Raynor, Chadley Froes
Journal: Case Rep Gastrointest Med (2021)
MeSH terms: Case Reports

Gastric diverticula are the least common gastrointestinal diverticula. Patients can be diagnosed incidentally on EGD or present with variable symptoms such as abdominal fullness, anorexia, and perforation. Gastric diverticula can be acquired from malignancy, peptic ulcer disease, or prior surgery or be congenital. Treatment varies based on symptomatology ranging from conservative medical management with proton pump inhibitors to surgical treatment with open or laparoscopic resection. We present a case of a 73-year-old female with acquired gastric diverticulum presenting as a gastric outlet obstruction who was successfully treated with conservative medical therapy.
A minor modification of direct browplasty technique in a patient with brow ptosis secondary to facial paralysis: copy-paste-excise and stitch
Authors: Arzu Taskiran Comez, Baran Gencer, Selcuk Kara, Hasan Ali Tufan
Journal: Case Rep Ophthalmol Med (2013)

Purpose. This report aimed to describe a minor modification of the traditional direct browplasty technique that aids in surgical planning for patients with brow ptosis secondary to facial paralysis without changing the shape of the brow. Case Report. A 74-year-old male patient with left facial paralysis secondary to chronic otitis media was referred with a complaint of low vision due to brow ptosis. We performed direct browplasty with a minor modification in order to aid a treatment customized to the patient. In this technique, a transparent film paper is used to copy the brow shape. A brow-shaped excision is facilitated just superior to the ptotic brow. Conclusion. The authors found that the copy-paste-excise and stitch technique was effective and successful for deciding the shape and the amount of excision that should be performed in patients with brow ptosis without resulting in asymmetrical, arched, and feminized brows.
Chronic Neuropsychological Sequelae in a Patient with Nontumorous Anti-NMDA-Receptor Encephalitis
Authors: Dong Y Han, Lisa M Koehl, Aarti Patel, Zhengqiu Zhou, Sarah Phillips, Siddharth Kapoor
Journal: Case Rep Neurol Med (2017)
MeSH terms: Case Reports

Anti-N-methyl-D-aspartate receptor encephalitis is a neurological, autoimmune disorder tightly conceptualized only as recently as the mid-2000s. It presents itself in a combination of psychiatric, neurological, and autonomic features. We observe a unique case with probable earlier episode (prior to the mid-2000s conceptualization of the disease) and a later relapse, accompanying a comprehensive neuropsychological profile tracked after the relapse and subsequent improvement. Neurocognitive findings revealed residual frontal deficits with mood changes even in the state after plasmapheresis. This case is the first to describe posttreatment cognition in anti-NMDAR encephalitis after probable serial autoimmune episodes.
Identification of novel mutation in cathepsin C gene causing Papillon-Lefèvre Syndrome in Mexican patients
Authors: José G Romero-Quintana, Luis O Frías-Castro, Eliakym Arámbula-Meraz, Maribel Aguilar-Medina, Jesús E Dueñas-Arias, Jesús D Melchor-Soto, José G Romero-Navarro, Rosalío Ramos-Payán
Journal: BMC Med Genet (2013)
MeSH terms: Cathepsin C / genetics, Mutation, Papillon-Lefevre Disease / genetics, Case Reports, Research Support, Non-U.S. Gov't, Adolescent, Adult, Cathepsin C / metabolism, Child, Child, Preschool, Female, Gene Expression, Gene Frequency, HLA-DRB1 Chains / genetics, Humans, Infant, Male, Mexico, Middle Aged, Polymorphism, Single-Stranded Conformational, Young Adult, HLA-DRB1 Chains, CTSC protein, human, Cathepsin C

Background:
Papillon-Lefèvre Syndrome (PLS) is a type IV genodermatosis caused by mutations in cathepsin C (CTSC), with a worldwide prevalence of 1-4 cases per million in the general population. In México, the prevalence of this syndrome is unknown, and there are few case reports. The diagnosis of twenty patients in the state of Sinaloa highlights the need to characterize this syndrome in Mexicans.
Methods:
To understand the basis of PLS in Mexicans, the gene expression, enzymatic activity and mutational analysis of CTSC were assayed in nine PLS patients and their relatives. Frequencies of CTSC gene polymorphisms and HLA alleles were determined in these patients, their relatives, and the population.
Results:
Patients showed normal CTSC gene expression, but a deep reduction (up to 85%) in enzymatic activity in comparison to unrelated healthy individuals. A novel loss-of-function mutation, c.203 T > G (p.Leu68Arg), was found in all patients, and some carried the polymorphism c.458C > T (p.Thr153Ile). Allelic frequencies in patients, relatives and controls were 88.89%, 38.24% and 0.25% for G (c.203 T > G); and 11.11%, 8.82% and 9.00% for T (c.458C > T). HLA-DRB1*11 was found significantly more frequent (P = 0.0071) in patients than controls (33.33% vs. 7.32%), with an estimated relative risk of 6.33.
Conclusions:
The novel loss-of function mutation of CTSC gene (c.203 T > G) found in patients correlated with their diminished enzymatic activity, and HLA-DRB1*11 was found to be associated with PLS. The study of more PLS patients may give more insights into the etiology of the disease as well as its prevalence in México.
A Japanese Patient with Genitopatellar Syndrome Transiently Presenting with Cardiac Intramural Cavity during the Neonatal Period
Authors: Kiichi Takahashi, Hiroyuki Adachi, Manatomo Toyono, Masato Ito, Akie Kato, Atsuko Noguchi, Tsutomu Takahashi
Journal: Case Rep Genet (2020)
MeSH terms: Case Reports

Genitopatellar syndrome (GPS) is a rare autosomal dominant disorder caused by de novo pathogenic variants in the KAT6B gene. It is characterized by genital abnormalities, patellar hypoplasia/agenesis, flexion contractures of the hips and knees, corpus callosum agenesis with microcephaly, and hydronephrosis and/or multiple renal cysts. More than half of patients with GPS have congenital heart defects, mostly atrial and/or ventricular septal defects, patent foramen ovale, and patent ductus arteriosus. We report a case of a Japanese neonate with a de novo heterozygous c.3769_3772delTCTA pathogenic variant in the KAT6B gene who presented with a cardiac intramural cavity of the ventricular septum at birth. The cavity unexpectedly disappeared at 1 month of age, but trabecular septal thinning and flash remained. The features of the cavity were not consistent with those of congenital ventricular diverticulum or aneurysm, and its identity and prognosis are still unclear. Because patients with GPS may exhibit various forms of cardiac malformation, careful cardiac examination and follow-up are required from birth in cases of suspected GPS.
Pulmonary artery sling in a symptomatic newborn
Authors: İlker Mercan, Muhammet Akyuz, Onur Işık
Journal: J Cardiovasc Thorac Res (2021)
Keywords: airway obstruction, pulmonary arterial sling, surgery
MeSH terms: Case Reports

Pulmonary arterial sling (PAS) is a relatively rare congenital anomaly in which left pulmonary artery branch originates abnormally from the right pulmonary artery, eventually resulting with respiratory symptoms, due to airway obstruction. In this report, we present a PAS in a neonate who showed progressive respiratory distress in the second week following delivery. At 25 days of age, the patient underwent total surgical correction of the anomaly, during which left pulmonary artery reimplantation to main pulmonary artery without the use of cardiopulmonary bypass was employed. Following an uneventful recovery, the patient was discharged eighteen days after surgery.
Rare Cases of Pediatric Vasoactive Intestinal Peptide Secreting Tumor With Literature Review: A Challenging Etiology of Chronic Diarrhea
Authors: Pai-Jui Yeh, Shih-Hsiang Chen, Jin-Yao Lai, Ming-Wei Lai, Cheng-Hsun Chiu, Hsun-Chin Chao, Shih-Hsin Chen, Ren-Chin Wu, Chao-Jan Wang, Chien-Chang Chen
Journal: Front Pediatr (2020)
Keywords: wdha syndrome, case report, children, diarrhea, tumor, vasoactive intestinal peptide
MeSH terms: Case Reports

Vasoactive intestinal peptide (VIP) secreting tumor (VIPoma) is a rare disease, presenting with profuse diarrhea, electrolyte imbalance, and possibly fatal outcome. The diagnosis and treatment are challenging, and no consensus guideline of management is available. The pediatric incidence remains unclear. This study comprises two pediatric case reports from a tertiary center and a literature-based case series investigating the characteristics among children. The two reported cases both presented with severe diarrhea and laboratory abnormalities, including electrolyte imbalance and elevated plasma VIP level. Case 1 received several imaging investigations, partial pancreatectomy, octreotide, and everolimus, reflecting her complicated and refractory course. Case 2 underwent total excision of suprarenal ganglioneuroblastoma, and the clinical response was significant. In both cases, varied degrees of symptomatic control, reduced plasma VIP level, and correction of electrolyte imbalance were achieved. A literature review-based case series analyzed 45 pediatric cases retrieved from the PubMed database until December 31, 2019. Demographics, clinical features, diagnostic modalities, treatments, and outcomes were presented.
Malignant transformation of abdominal wall endometriosis to clear cell carcinoma: case report
Authors: João Kleber de Almeida Gentile, Renato Migliore, Fábio Jorge Neubaner Kistenmacker, Marcio Menezes de Oliveira, Rodrigo Biscuola Garcia, Fang Chia Bin, Pedro Marcos Santinho Bueno de Souza, José César Assef
Journal: Sao Paulo Med J (2018)
MeSH terms: Abdominal Neoplasms / etiology, Adenocarcinoma, Clear Cell / etiology, Cell Transformation, Neoplastic / pathology, Endometriosis / complications, Lymphatic Metastasis / pathology, Case Reports, Abdominal Neoplasms / pathology, Abdominal Neoplasms / surgery, Abdominal Wall / surgery, Adenocarcinoma, Clear Cell / pathology, Adenocarcinoma, Clear Cell / surgery, Adult, Female, Humans, Lymph Node Excision, Neoadjuvant Therapy, Tomography, X-Ray Computed

Background:
Malignant transformation of endometriosis in the abdominal wall is a rare and still poorly understood event. Less than 30 cases have been reported in the worldwide literature. Most cases of solid tumors are report in a previous abdominal scar with malignant transformation of a focus of endometriosis. Presence of lymph node metastases in nearby chains is frequent and is associated with poor prognosis.
Case report:
We report a case of a 42-year-old woman with a history of abdominal surgery (Pfannenstiel) to resect abdominal wall endometriosis. Physical examination revealed a solid mass of approximately 10 cm x 6 cm in the anterior wall of the abdomen. Computed tomography (CT) of the abdomen and pelvis showed a heterogeneous, predominantly hypoattenuating expansive formation measuring 10.6 cm x 4.7 cm x 8.3 cm. The patient underwent exploratory incisional laparotomy, block resection of the abdominal mass and lymphadenectomy of the external and inguinal iliac chains. The abdominal wall was reconstructed using a semi-absorbable tissue-separating screen to reconstitute the defect caused by resection of the tumor. Histological evaluation revealed infiltration by malignant epithelioid neoplasia, thus confirming the immunohistochemical profile of adenocarcinoma with clear cell components. Lymphadenectomy showed metastatic involvement of an external iliac chain lymph node.
Conclusion:
Resection of the mass along with the abdominal wall, with wall margins, is the most effective treatment. Reconstruction is a challenge for surgeons. The patient has been followed up postoperatively for eight months, without any evidence of disease to date.
The Diagnosis and Treatment of Multiple Factitious Oral Ulcers in a 6-Year-Old Boy
Authors: Priscilla Santana Pinto Gonçalves, Daniela Alejandra Cusicanqui Mendez, Paulo Sérgio da Silva Santos, José Humberto Damante, Daniela Rios, Thiago Cruvinel
Journal: Case Rep Dent (2017)
MeSH terms: Case Reports

Factitious ulcers are characterized by self-inflicted lesions with multifactorial origin. These lesions are frequently found in head, neck, and hands. This report shows a 6-year-old boy diagnosed with factitious oral ulcers that occurred after the self-biting of buccal vestibule and nail-scratching of gingival tissue. Clinically, a significant swelling was observed, hard on palpation, located at the right lower third of the face, next to the posterior area of the mandible. In the intraoral examination, ulcers at different healing stages were noted on the swelling area. During the anamnesis, the father reported a change in his familial structure that triggers psychological stress, providing the clues to the presumptive diagnosis of factitious oral ulcers. We prescribed the topical use of Gingilone® three times a day to control the local pain and inflammation. At 7-day follow-up, we noticed the reduction of extraoral swelling and the initial healing of the ulcers. The presumptive diagnosis was confirmed at 30-day follow-up, with the lasting remission of oral lesions. The treatments of factitious oral ulcers should be individually tailored for each patient, focused on a multidisciplinary approach, including psychotherapy and periodic clinical control. To the best of our knowledge, gaps of evidence lead to the lack of standardized clinical protocols on this issue.