OpenMed/multicare-articles huggingface dataset:
Drug-induced eosinophilic pneumonia: A review of 196 case reports
Authors: Carmi Bartal, Iftach Sagy, Leonid Barski
Journal: Medicine (Baltimore) (2018)
MeSH terms: Anti-Bacterial Agents / adverse effects, Anti-Inflammatory Agents, Non-Steroidal / adverse effects, Pulmonary Eosinophilia / chemically induced, Review, Acute Disease, Adult, Chronic Disease, Daptomycin / adverse effects, Eosinophils, Female, Humans, Male, Mesalamine / adverse effects, Middle Aged, Minocycline / adverse effects, Pulmonary Eosinophilia / blood, Sulfasalazine / adverse effects, Anti-Bacterial Agents, Anti-Inflammatory Agents, Non-Steroidal, Sulfasalazine, Mesalamine, Minocycline, Daptomycin

Background and objective:
Eosinophilic pneumonia (EP) is an important subset of patients who present with pulmonary infiltrates and eosinophilia (PIE). EP is classified by chronicity and etiology and drug-induced EP is the main cause of secondary EP. The primary goal of this review was to examine all the case reports published since the syndrome was defined in 1990. It remains unclear whether acute or chronic EP (AEP or CEP) represent different diseases, and the secondary goal of this review is to determine if there are factors that may help distinguish these 2 entities.
Methods:
PubMed (MEDLINE and Medical Subject Headings) was searched for case reports of drug-induced EP or PIE syndrome published between 1990 and 2017. Case reports were only included if the diagnostic criteria for AEP or CEP were fulfilled. For each case, data were extracted pertaining to age, sex, type of medication associated with the disease, time from the onset of symptoms to diagnosis, eosinophil counts in the blood, eosinophil fractions in bronchoalveolar lavage (BAL) fluid, initial chest radiograph and computed tomography results, use of mechanical ventilation, and use of steroid treatment and recurrence.
Results:
We found 196 case reports describing drug-induced EP. The leading cause was daptomycin. From our review, we found that AEP is more common in younger patients with no gender preference. Eosinophilia in the blood at the time of diagnosis characterized only the CEP patients (80% in CEP vs. 20% in AEP). Abnormal findings on radiographic imagine was similar in both syndromes. A significant portion of AEP patients (20%) presented with acute respiratory failure requiring mechanical ventilation. Most patients with EP were treated with steroids with a higher rate of relapse observed in patients with CEP.
Conclusion:
AEP is a much more fulminant and severe disease than the gradual onset and slowly progressive nature of CEP. The pathogenesis of AEP and CEP remains unclear. However, there is significant clinical overlap among AEP and CEP that are associated with drug toxicity, suggesting the possibility that AEP and CEP are distinct clinical presentations that share a common pathogenic pathway.
Flare-Up Diverticulitis in the Terminal Ileum in Short Interval after Conservative Therapy: Report of a Case
Authors: Kensuke Nakatani, Takaharu Kato, Shinichiro Okada, Risa Matsumoto, Kazuhiro Nishida, Hiroyasu Komuro, Maki Iida, Shiro Tsujimoto, Toshiyuki Suganuma
Journal: Case Rep Surg (2016)
MeSH terms: Case Reports

Diverticulitis in the terminal ileum is uncommon. Past reports suggested that conservative therapy may be feasible to treat terminal ileum diverticulitis without perforation; however, there is no consensus on the therapeutic strategy for small bowel diverticulitis. We present a 37-year-old man who was referred to our hospital for sudden onset of abdominal pain and nausea. He was diagnosed with diverticulitis in the terminal ileum by computed tomography (CT). Tazobactam/piperacillin hydrate (18 g/day) was administered. The antibiotic treatment was maintained for 7 days, and the symptoms disappeared after the treatment. Thirty-eight days after antibiotic therapy, he noticed severe abdominal pain again. He was diagnosed with diverticulitis in terminal ileum which was flare-up of inflammation. He was given antibiotic therapy again. Nine days after antibiotic therapy, laparoscopy assisted right hemicolectomy and resection of 20 cm of terminal ileum were performed. Histopathology report confirmed multiple ileal diverticulitis. He was discharged from our hospital 12 days after the surgery. Colonoscopy was performed two months after the surgery and it revealed no finding suggesting inflammatory bowel disease. Surgical treatment should be taken into account as a potential treatment option to manage the diverticulitis in the terminal ileum even though it is not perforated.
Long-Term Outcome of Autotransplantation of a Complete Root Formed a Mandibular Third Molar
Authors: Hiroyuki Kimura, Yusuke Hamada, Taro Eida, Tsuyoshi Kumano, Kazutoshi Okamura, Makoto Yokota
Journal: Case Rep Dent (2021)
MeSH terms: Case Reports

Autogenous tooth transplantation is a procedure to reposition an autogenous tooth to another extraction area or surgically created recipient site. The autotransplantation procedures have been documented well in the literature, and the survival rate of the transplanted teeth was reported to be more than 90% after ten years. Therefore, autotransplantation might have been overlooked as a treatment option. The purpose of this case report is to evaluate the long-term (29-year) success and periodontal stability of the tooth autotransplantation from the mandibular third molar to the second molar. A 24-year old female presented to a clinic with a large caries lesion with periapical radiolucnecy on to tooth #18. The tooth was extracted with the site and treated with autogenous tooth transplantation from #17 with a complete root form. Endodontic treatment was completed 3 months post autotransplantation; the final prosthesis was placed 6 months postoperatively. The patient has shown excellent oral hygiene care and high compliance with the regular maintenance recall program. The transplanted tooth has been still functioning without any symptoms. Radiographic and clinical examinations revealed stable periodontal and endodontic conditions over the 29 years after the procedure. This case report showed the long-term success of autotransplantation of the mandibular third molar with a closed root apex to the second molar site. Autotransplantation can be an option when an adequate donor site is available to reconstruct the occlusion after the tooth extraction.
Transcatheter Closure of Postinfarction Ventricular Septal Defect: A Case Report and Review of Literature
Authors: Mahmood M Shabestari, Fereshteh Ghaderi, Ali Hamedanchi
Journal: J Cardiovasc Thorac Res (2015)
Keywords: amplatzer occluder device, interventional closure, myocardial infarction, ventricular septal rupture
MeSH terms: Case Reports

Ventricular septal rupture (VSR) is an uncommon but serious complication of acute myocardial infarction (MI), associated with a high mortality rate. Although early surgical treatment improves the prognosis, hospital mortality after emergency surgery remains high. Transcatheter closure of postmyocardial infarction ventricular septal defect (PIVSD) has emerged as a potential strategy in selected cases. Current interventional reports are mainly restricted to PIVSD closure in the chronic and subacute setting, which only give a short term result. Herein, we report a case of acute post-MI VSR that was successfully closed using an Amplatzer postinfarction muscular ventricular septal defect (PIMVSD) occluder device with good immediate and long-term outcomes. The patient had undergone urgent coronary artery bypass surgery 3 days earlier in the setting of acute MI.
Chronic relapsing inflammatory optic neuropathy
Authors: Monica Saini, Dheraj Khurana
Journal: Ann Indian Acad Neurol (2010)
Keywords: recurrent optic neuritis, steroid responsive
MeSH terms: Case Reports

Chronic relapsing inflammatory optic neuropathy (CRION) is a recently described recurrent optic neuropathy which is steroid responsive. Several features distinguish this entity from optic neuritis associated with demyelinating disorders and connective tissue diseases. The severe degree of visual loss, persistence of pain after onset of visual loss, and recurrent episodes are unique to this disorder. We describe here a patient who presented with recurrent episodes of painful visual loss, followed by resolution of deficits, over a period of ten years. He was diagnosed as isolated optic neuritis conforming to features of CRION.
Contralateral approach to a carotid bifurcation aneurysm in a case of multiple intracranial aneurysms: a case report
Authors: Seyed Ali F Tabatabai, Ali Tayebi Meybodi, Mohammad Hashemi, Zohreh Habibi
Journal: Cases J (2009)

Background:
Traditionally, surgery of the anterior circulation aneurysms of the cerebral vasculature is dictated by the site of the lesion, excluding such midline lesions as anterior communication artery aneurysms. Few reports address the issue of using a single craniotomy to obliterate multiple aneurysms located in both hemispheres.
Case presentation:
A 51 year-old Caucasian right handed housewife lady (weight 61 kg, height 159 cm) presented with a headache of acute onset which proved to be caused by acute subarachnoid hemorrhage. Cerebral computed tomographic angiography revealed multiple aneurysms. The patient underwent a right pterional craniotomy to obliterate right middle cerebral, distal basilar and left carotid bifurcation aneurysms. The post-operative course was uneventful.
Conclusion:
Despite technical difficulties of approaching cerebral vasculature through a contralateral craniotomy, this policy is advised in selected cases in which the benefits of unilateral craniotomy outweigh the risks of brain retraction.
Brown Bowel Syndrome in a Middle-Aged Woman with Chronic Idiopathic Malabsorption
Authors: Renato Parente, Maurizio Pinamonti, Stefania Martina
Journal: Case Rep Surg (2019)
MeSH terms: Case Reports

Brown bowel syndrome (BBS) is an extremely unusual condition characterized by an orange-brown discoloration of the bowel and intestinal motility disorders secondary to fat-soluble vitamin deficiency and malabsorption from many different causes. We present the case of a middle-aged woman suffering for years of chronic constipation with recurrent intestinal subocclusion, who was diagnosed BBS on surgical biopsy material. Nutritional supplementary treatment was tried, but her symptoms did not improve, and a decision was finally made in favor of a surgical approach. After subtotal colectomy and continual vitamin nutritional supplementation, she has now regular transit without the use of laxatives. BBS is a rare complication of long-term malabsorption manifesting as intestinal motility disorders, which can lead to severe complications. This condition is only partially responsive to vitamin supplementation, and most cases require surgery.
Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation
Authors: Silje Johansen, Jostein Kråkenes, C A Vedeler, Anette Margrethe Storstein, Håkon Reikvam
Journal: Case Reports Immunol (2022)
MeSH terms: Case Reports

A woman with myelodysplastic syndrome (MDS) was treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). 65 days after the transplantation, she developed fatigue and central neurological symptoms. Clinical workup including magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) examination revealed findings suspicious for limbic encephalitis (LE), successfully treated with intravenous immunoglobulins and intravenous corticosteroids. Although a rare complication after allo-HSCT, physicians should be aware of neurological symptoms that develop throughout the transplantation course.
Technical Innovation Case Report: Ultrasound-Guided Prolotherapy Injection for Insertional Achilles Calcific Tendinosis
Authors: Benjamin K Buchanan, Jesse P DeLuca, Kyle P Lammlein
Journal: Case Rep Orthop (2016)

We describe the use of ultrasound guidance for hyperosmolar dextrose (prolotherapy) injection of the distal calcaneal tendon specifically just anterior to identified enthesophytes in patients with insertional Achilles calcific tendinosis refractory to conservative treatment. This specific technique has not to our knowledge been described or used in literature previously.
Sense of place and experimentation in urban sustainability transitions: the Resilience Lab in Carnisse, Rotterdam, The Netherlands
Authors: Niki Frantzeskaki, Frank van Steenbergen, Richard C Stedman
Journal: Sustain Sci (2018)
Keywords: cities, experimentation, sense of place, sustainability, urban transitions, vision

Experimentation as a means of governance for sustainability transitions has been advocated for years by transition scholars and geography scholars. We propose that examining the impact of experimentation requires an understanding of its embeddedness in place as a socio-spatial context. This notion of embeddedness, which conceptually aligns well with the understanding of sense of place, is under-examined in sustainability transitions literature. By conjoining the sense of place and sustainability transition literatures, we conceptualize that sense of place can be one outcome of experimentation fostering sustainability transitions. We examine urban living labs as an open format of urban experimentation, where multiple actors interact with the aim to co-design, test, and implement governance innovations. From the literature, we have distilled three phenomena that relate to a sense of place as mechanisms for transformation: a symbolic understanding or meaning of place; a narrative of place that connects to a transformative vision; and new types of relations between people and place. With this conceptual lens, we analyze our case study, an urban living lab called The Resilience Lab in a neighborhood of the city of Rotterdam, The Netherlands. Drawing from a longitudinal case study research, we contend that urban living labs can connect a sense of change (transformation) with a sense of place by co-creating new narratives of place, by co-producing knowledge on new practices and new relations between people and place, and by allowing the co-design or (re)establishment of places with symbolic meaning. As such, urban living labs facilitate urban sustainability transitions.
Necrotizing pneumonia caused by Panton-Valentine leucocidin-producing Staphylococcus aureus originating from a Bartholin's abscess
Authors: N Jung, C Lehmann, M Hellmann, H Seifert, M M Valter, M Hallek, G Fätkenheuer, M Kochanek
Journal: Infect Dis Obstet Gynecol (2008)
MeSH terms: Abdominal Abscess / complications, Anti-Bacterial Agents / therapeutic use, Bacterial Toxins / biosynthesis, Exotoxins / biosynthesis, Leukocidins / biosynthesis, Pneumonia, Staphylococcal / complications, Staphylococcus aureus / metabolism, Case Reports, Abdominal Abscess / drug therapy, Abdominal Abscess / microbiology, Abdominal Abscess / pathology, Bartholin's Glands, Combined Modality Therapy, Drug Therapy, Combination, Female, Humans, Immunocompetence, Lung Abscess / complications, Lung Abscess / drug therapy, Lung Abscess / microbiology, Lung Abscess / pathology, Pneumonia, Staphylococcal / drug therapy, Pneumonia, Staphylococcal / microbiology, Pneumonia, Staphylococcal / pathology, Staphylococcus aureus / drug effects, Staphylococcus aureus / isolation & purification, Treatment Outcome, Young Adult, Anti-Bacterial Agents, Bacterial Toxins, Exotoxins, Leukocidins, Panton-Valentine leukocidin

Background:
Panton-Valentine leukocidin (PVL-)producing Staphylococcus aureus is emerging as a serious problem worldwide. There has been an increase in the incidence of necrotizing lung infections in otherwise healthy young people with a very high mortality associated with these strains. Sporadic severe infectious complications after incision of Bartholin's abcesses have been described but involvement of S. aureus is rare.
Case report:
We present a 23-year-old apparently healthy female patient without any typical predisposing findings who developed severe sepsis with necrotizing pneumonia and multiple abscesses following incision of a Bartholin's abscess. Methicillin-sensitive S. aureus harbouring Panton-Valentine leucocidin genes were cultured from the abscess fluid, multiple blood cultures and a postoperative wound swab. Aggressive antibiotic therapy with flucloxacillin, rifampicin and clindamycin, drainage and intensive supportive care lead finally to recovery.
Conclusions:
S. aureus, in particular PVL-positive strains, should be considered when a young, immunocompetent person develops a fulminant necrotizing pneumonia. Minor infections--such as Bartholin's abscess--can precede this life-threating syndrome. Bactericidal antistaphylococcal antibiotics are recommended for treatment, and surgical procedures may become necessary.
Case report: Umbilical vessel aneurysm thrombosis and factor V Leiden mutation leading to fetal demise
Authors: Camélia Oualiken, Olivia Martz, Nadia Idrissi, Fara Tanjona Harizay, Laurent Martin, Emmanuel De Maistre, Lou Ricaud, Georges Tarris
Journal: Front Med (Lausanne) (2023)
Keywords: fetal demise, stillbirth, thrombophilia, thrombosis, umbilical artery aneurysm, umbilical vessel aneurysm
MeSH terms: Case Reports

Complicated pregnancies are nowadays a major public health concern, with possible lethality or sequelae both for the mother and the fetus. Blood coagulation disorders (including antiphospholipid syndrome, factor V Leiden mutation and antithrombin deficiency) and hypertensive gestational disorders are very well-known contributors of complicated pregnancies with poor fetal outcome, such as intrauterine growth retardation (IUGR) and fetal demise. Less commonly, vascular malformations of the placenta can also potentially lead to serious complications such as IUGR and fetal death. These malformations include hypercoiled umbilical cord, umbilical cord knot, umbilical cord varix, umbilical cord arterial or venous aneurysm, and velamentous insertion of the umbilical cord potentially leading to Benckiser's hemorrhage. Here, we report the case of a 29-year-old Gravida 2 Para 0 mother with previous history of stillbirth and smoking, admitted to the obstetrics department for the absence of fetal movement at 38 weeks of amenorrhea (WA). First-trimester and second-trimester routine ultrasounds were otherwise normal. Ultrasound performed at 38 WA revealed a 83 × 66 × 54 mm cystic heterogenous mass at the umbilical cord insertion. After delivery, fetal and placental pathology as well as maternal blood testing were performed. Fetal pathology was otherwise normal, except for diffuse congestion and meconial overload suggesting acute fetal distress. Fetal karyotype was normal (46 XX). Placental pathology revealed an umbilical artery aneurysm (UAA) at the base of the insertion of the umbilical cord, lined with a CD34+ CD31+ endothelium. After dissection, the aneurysm was filled with hemorrhagic debris, indicating aneurysm thrombosis. Histopathology revealed associated maternal vascular malperfusion (MVM) and increased peri-villous fibrin (IPF). Maternal blood tests revealed heterozygous factor V Leiden mutation, without other associated auto-immune conditions (such as antiphospholipid syndrome). Umbilical artery aneurysms remain extremely rare findings in the placenta, with <20 reported cases. Umbilical artery aneurysms have tendency to be located at the base of the insertion of the placenta, and lead to fetal demise in more than 60% of cases, mainly due to aneurysmal thrombosis, hematoma, possible vascular compression and/or rupture. Umbilical vessel aneurysms can be associated with trisomy 18 or 13. In our case, the association of factor V Leiden mutation, a hypercoagulable state, with UAA could explain massive thrombosis of the aneurysmal lumen and sudden fetal demise. Further consideration of current guidelines for surveillance and management of UAA would allow appropriate planned delivery in maternal care settings.
Hybrid endovascular repair of aneurysmal right-sided aortic arch and Kommerell's diverticulum using a two-vessel branched stent graft: Case report and review of literature
Authors: Mo Hamady, Paritosh M Sharma, Radhika Patel, Anthony D Godfrey, Colin D Bicknell
Journal: SAGE Open Med Case Rep (2017)
Keywords: kommerell’s diverticulum, thoracic aorta, aneurysm, branch stent graft, right-sided arch, thoracic endovascular aortic repair
MeSH terms: Case Reports

Right-sided aortic arches are rare, affecting approximately 0.1% of the population. They are a result of abnormal development of the primitive aortic arches and may present later in life with later life with aneurysmal expansion of the aberrant left subclavian artery 'Kommerell's diverticulum'. These can be challenging to treat effectively. We report a rare case presenting with mild dysphagia and right-sided aneurysmal aortic arch with aneurysmal aberrant left-sided. The patient underwent hybrid endovascular repair incorporating bilateral carotid-subclavian bypasses and dual-arch-branch endograft placement to the left and right common carotid arteries. Although endovascular approaches have been described, there are no reports of branched endografts in this scenario. Right-sided aneurysmal aortic arch and the aneurysmal aberrant left subclavian artery are rare and represent a significant therapeutic challenge. Endovascular repair in conjunction with extra-anatomical bypass utilising a custom-made branched thoracic endograft is feasible.
Aetiology of femoral hernias revisited: bilateral femoral hernia in a young male (two cases)
Authors: R T Kochupapy, G Ranganathan, S Dias, D Shanahan
Journal: Ann R Coll Surg Engl (2013)
MeSH terms: Hernia, Femoral / etiology, Case Reports, Adult, Hernia, Femoral / diagnosis, Hernia, Femoral / surgery, Humans, Male, Physical Examination, Recurrence, Reoperation, Sex Factors, Young Adult

Bilateral femoral hernias are less common in men than in women and rare in young adults. Only one case of a bilateral femoral hernia in a young man has been reported in the literature before. Three main theories have been postulated for femoral hernias. The theory that they are an acquired disease is the most accepted due to the common occurrence of such hernias in multiparous women but the theory lacks enough evidence. We report two cases in young men. Anatomical variations in the femoral canal could be the primary aetiological factor in these patients. A unilateral femoral hernia in young men with acquired aetiological factors requires a clinical examination of the opposite side.