OpenMed/multicare-articles huggingface dataset:
Fixation of metatarsal fracture with bone plate in a dromedary heifer
Authors: S A Siddiqui, M I Siddiqui, M N Telfah, S Hashmi
Journal: Open Vet J (2013)
Keywords: bone plating, camel, fracture, interfragmental compression, metatarsus
MeSH terms: Case Reports

An oblique fracture of the distal third of the right metatarsus in a three-year-old dromedary heifer weighing about 300 kilograms was immobilized with a 4.5 mm broad-webbed 12-hole dynamic compression bone plate and two interfragmental compression screws. The animal showed slight lameness after 16 weeks of surgery that disappeared after removal of the plate. The result was quite encouraging and the fracture healed in 16 weeks without major complications. It is concluded that the fracture of this bone can be successfully handled with bone plating at least in young, light weight animals.
A Case of Gastric Intramural Hematoma Caused by Anisakis Infection
Authors: Sang Jin Lee
Journal: Case Rep Gastrointest Med (2020)
MeSH terms: Case Reports

A sixty-year-old lady admitted complaining of epigastric pain and hematemesis. On admission, esophagogastroduodenoscopic examination revealed ruptured intramural hematoma on the antrum of stomach. Eight days later, follow-up EGD showed improving ruptured intramural hematoma and one anisakis larva. Therefore, the gastric intramural hematoma was considered to be caused by anisakis infection. She recovered after ten days of conservative treatment.
Ischemic stroke related to HIV and SARS-COV-2 co-infection: a case report
Authors: Paula Bonates Bessa, Andreza Karoline Barros Brito, Flávio Ribeiro Pereira, Sildomar Queiroz E Silva, Taynná Vernalha Rocha Almeida, André Patrício de Almeida
Journal: Rev Soc Bras Med Trop (2020)
MeSH terms: Brain Ischemia / virology, COVID-19 / complications, HIV Infections / complications, Ischemic Stroke / virology, Case Reports, Antibodies, Viral, Brain Ischemia / diagnostic imaging, Coinfection / virology, Humans, Immunoglobulin G, Immunoglobulin M, Ischemic Stroke / diagnostic imaging, Magnetic Resonance Imaging, Male, Middle Aged, SARS-CoV-2, Antibodies, Viral, Immunoglobulin G, Immunoglobulin M

A 56-year-old male with human immunodeficiency virus required hospitalization due to the onset of both dyspnea and asthenia. A computed tomography of the chest exam showed the radiological pattern of coronavirus SARS-CoV-2 pulmonary involvement. Based on immunochromatographic analysis, the patient evolved as a reagent for immunoglobulin M (IgM) and immunoglobulin G (IgG) anti-SARS-CoV-2 antibodies. The individual developed complete hemiparesis with a predominance in the right arm and conduction aphasia. T1-weighted magnetic resonance sequence of the brain showed an area of hypointensity with a high intrinsic cortical signal and hyperintensity in the T2-sequence. A Doppler velocimetric examination showed total/critical sub occlusion, suggesting an ischemic stroke.
Auditory hallucinations in a deaf patient: a case report
Authors: Natalia Pedersen, René Ernst Nielsen
Journal: Case Rep Psychiatry (2013)

This case report describes the progression of symptoms in a young deaf female. Her initial psychotic symptoms occur at the age of 16, but she did not come into contact with a psychiatric treatment facility before the age of 27, where she felt symptoms were distressing. The case report describes the difficulties in evaluating psychotic symptoms in a deaf patient, as well as the use of specialized scales in combination with the standard psychiatric evaluation. The current evidence, concerning the prevalence of psychotic symptoms, as well as the influence of deafness on the understanding of psychosis, is described.
An intra-abdominal abscess or "rind" as a consequence of peritoneal dialysis-associated pseudomonas peritonitis
Authors: R Michael Culpepper, Sarah Gore, Gregory W Rutecki
Journal: Clin Nephrol Case Stud (2013)
Keywords: pseudomonas aeruginosa, peritoneal dialysis, peritonitis, rind formation
MeSH terms: Case Reports

Background:
Abdominal CT imaging has defined characteristics of two pathological entities specific to peritoneal dialysis patients. Both are associated with serious peritoneal complications. One is comprised of ascites accompanied by septation and loculated fluid pockets as a complication of bacterial peritonitis. The other is the syndrome of encapsulating peritoneal sclerosis. We present the evolution of a single, thick-walled fluid collection as a consequence of relapsing Pseudomonas aeruginosa peritonitis. The entity had distinctive features differing from either of the two previously described entities, and to our knowledge, has not been described previously. Our patient's radiological evolution resembled the formation of a pleural or peritoneal "rind."
Conclusion:
Peritonitis, as a result of Pseudomonas aeruginosa, may lead to "rind" formation as described with empyemas and is distinct from previously described intra-abdominal pathologies in peritoneal dialysis patients.
Use of Aripiprazole Long Acting Injection in Negative Symptoms of Schizophrenia
Authors: Suneeta James, Chaya Kapugama, Mohammed Al-Uzri
Journal: Case Rep Psychiatry (2016)

Background. Evidence for the efficacious use of second-generation antipsychotics for the treatment of negative symptoms in schizophrenia is scant. Case Presentation. We report the case of a 34-year-old female of Afro-Caribbean origin, who presented with prominent negative symptoms of schizophrenia and was successfully treated with aripiprazole long acting injection. Within a period of six to nine months, the patient returned to her premorbid level of functioning. Conclusion. Aripiprazole long acting injection promises benefits in the treatment of negative symptoms of schizophrenia. Further research needs to be conducted on the use of this drug.
Case Report: Chimeric Antigen Receptor T Cells Induced Late Severe Cytokine Release Syndrome
Authors: Jinping He, Na Xu, Hongsheng Zhou, Ya Zhou, Di Wu, Ruochong Zhao, Tong Lin, Ju Xu, Rui Cao, Peng Li, Qifa Liu
Journal: Front Oncol (2022)
Keywords: chimeric antigen receptor t cell (cart), cutaneous toxic effect, haemophagocytic lymphohistiocytosis (hlh), late period, re-expansion, severe cytokine release syndrome (scrs)
MeSH terms: Case Reports

Background:
Severe cytokine release syndrome (sCRS) has emerged as an adverse complication in the early period of chimeric antigen receptor T cell (CART) therapy, while whether sCRS occurs in the late period remains unknown. Here, we reported two patients with late sCRS.
Case presentation:
Case 1 was a 34-year-old female with refractory Philadelphia chromosome-positive B cell acute lymphoblastic leukemia. She achieved complete remission (CR) but experienced grade III CRS and hemophagocytic lymphohistiocytosis (HLH) 41 days after CD19-targeted CART (CART19) cells and CD22-targeted CART (CART22) cells infusion. Ineffective to tocilizumab and HLH-94 protocol (dexamethasone and etoposide), she died of a cerebral hemorrhage on day 55 after CART therapy. Case 2 was a 38-year-old male with IgG kappa multiple myeloma. He received autologous BCMA-targeted CART (BCMA-CART) therapy 4 months after HLA-matched sibling (sister) donor transplantation and developed grade III CRS 163 days after CART administration, characterized by fever, hypotension, and skin lesions. Effective to methylprednisolone and tocilizumab, his clinical response persisted for over 6.0 months.
Conclusion:
Severe CRS could occur in the late period after CART therapy as re-expansion of CART cells possessed the potential risk for late sCRS.
The development of T-cell malignancies in patients with pre-existing myeloproliferative neoplasms: a report of three cases
Authors: Ethan A Burns, Kartik Anand, Betty Chung, Shilpan Shah, Jasleen K Randhawa, Sai Ravi Pingali
Journal: Ecancermedicalscience (2020)
Keywords: philadelphia negative myeloproliferative neoplasm, t-cell acute lymphoblastic leukaemia, angioimmunoblastic t-cell lymphoma, essential thrombocythemia, polycythemia vera, primary myelofibrosis
MeSH terms: Case Reports

Secondary acute myeloid leukaemia complicating the natural disease course of pre-existing Philadelphia chromosome-negative myeloproliferative neoplasms (PN-MPN) is well documented and associated with treatment challenges and significant morbidity. The incidence of a T-cell malignancy developing in patients with pre-existing PN-MPN is uncommon, with one case documented in the literature. We present two cases of angioimmunoblastic T-cell lymphoma (AITL) and one case of T-cell acute lymphoblastic leukaemia (T-ALL) that developed in patients with essential thrombocythemia (ET) and primary myelofibrosis (PMF), respectively. All malignancies were advanced at diagnosis and exhibited disease progression, regardless of the mutational status of the underlying ET/PMF, presence of cytogenetic abnormalities, type of T-cell neoplasm or systemic chemotherapy utilised. The median time to diagnosis of AITL or T-ALL from the onset of MPN was 4.5 years (range: 6 months-10 years). This single institutional case series demonstrates the possibility of an association between T-cell neoplasms and PN-MPNs.
A Rare Cause of Pulmonary Nodules Diagnosed as Angiosarcoma Was Misdiagnosed as Vasculitis and Wegener's Granuloma in an Elderly Man: A Case Report
Authors: Peixia Wang, Liqian Xu, Yunmei Yang
Journal: Front Oncol (2021)
Keywords: angiosarcoma, wegener’s granuloma, diagnostic errors, pulmonary nodule, vasculitis
MeSH terms: Case Reports

Background:
Angiosarcoma is a rare, highly malignant tumor prone to recurrence and metastasis. Angiosarcoma is insidious in the initial stage, and its clinical manifestation lacks specificity. The diagnosis is based on histopathology and immunohistochemistry findings.
Case presentation:
A 73-year-old man was hospitalized following complaints of persistent cough 6 months and hemoptysis for 2 months. Anti-infective treatment was ineffective. A CT-guided percutaneous core needle biopsy of pulmonary lesions revealed organized pneumonia, and the removed skin of purpuric rash area on the left calf revealed vasculitis. Chest CT was used during the patient follow-up. Hormonal therapy combined with immunoglobulins did not lead to improvement, and there was rapid progression of the lung lesions. Subsequently, the patient underwent a surgery, the diseased tissue was separated and removed completely beside the left submandibular gland under local anaesthesia. The immunohistochemical staining indicated CD31 (+) and CD34 (+) confirming a diagnosis of metastatic angiosarcoma. The expression of PD-L1 was 70%, therefore, anlotinib and pembrolizumab treatments were initiated. The patient eventually died.
Conclusion:
Angiosarcoma is a malignant tumor in the clinic that lacks typical and specific signs and symptoms. The diagnosis depends on immunohistochemistry, which requires repeated biopsies of multiple sites in highly suspected cases.
Occipitocervical Dislocation in Low-Energy Trauma
Authors: Celeste Tavolaro, Richard Bransford, Aditya Yerrapragada, Carlo Bellabarba, Haitao Zhou
Journal: Case Rep Orthop (2018)
MeSH terms: Case Reports

Traumatic occipitocervical dislocation (OCD) is described in the literature as a potentially fatal injury secondary to high-energy trauma. We describe a case of OCD occurring in a patient who sustained a ground-level fall whose only clinical symptom was posterior neck pain without neurologic compromise. Computed tomography (CT) and magnetic resonance imaging (MRI) were used to diagnose severe injury to the structurally important ligamentous complex that stabilizes the base of the skull to the spine, along with unstable fractures of the occipital condyle and C1. Emergent surgical instrumentation and fusion of occiput-C2 was performed. Postoperatively, neurologic integrity was maintained. This case illustrates that traumatic OCD is not exclusively secondary to high-energy mechanisms. It also demonstrates that severe neck pain as the only clinical manifestation in a patient with head or neck low-energy trauma is suggestive of a possible OCD. We highlight the importance of the use of head and neck CT as the first imaging-based diagnostic tool to aid in identifying this injury. Finally, surgical stabilization should be performed as soon as possible to minimize neurologic sequelae.
Foreign body in root canals of two adjacent deciduous molars: a case report
Authors: Kanika Singh Dhull, Sonu Acharya, Prayas Ray, Rachita Singh Dhull
Journal: Int J Clin Pediatr Dent (2013)
Keywords: deciduous molars, foreign body, root canals
MeSH terms: Case Reports

Children often tend to have the habit of inserting foreign objects in the oral cavity unknowingly for relief of dental pain. Sometimes, children do not reveal to their parents due to fear. These foreign objects may act as a potent source of infection and painful condition. The discovery of foreign bodies in the teeth is a special situation, which is often diagnosed accidentally. Detailed case history, clinical and radiographic examinations are necessary to come to a conclusion about the nature, size, location of the foreign body and the difficulty involved in its retrieval. Here is a case report, where foreign object was accidentally lodged in the carious deciduous molars by a child. How to cite this article: Dhull KS, Acharya S, Ray P, Dhull RS. Foreign Body in Root Canals of Two Adjacent Deciduous Molars: A Case Report. Int J Clin Pediatr Dent 2013;6(1):38-39.
Case Report: Rapid Treatment of Uridine-Responsive Epileptic Encephalopathy Caused by CAD Deficiency
Authors: Ling Zhou, Jie Deng, Sarah L Stenton, Ji Zhou, Hua Li, Chunhong Chen, Holger Prokisch, Fang Fang
Journal: Front Pharmacol (2020)
Keywords: cad deficiency, anaemia with anisopoikilocytosis, developmental delay, epilepsy, uridine
MeSH terms: Case Reports

We present two unrelated Chinese patients with CAD deficiency manifesting with a triad of infantile-onset psychomotor developmental delay with regression, drug-refractory epilepsy, and anaemia with anisopoikilocytosis. Timely translation into uridine supplementation, within 2-months of disease onset, allowed us to stop conventional anti-epileptic drugs and led to dramatic improvement in the clinical symptoms, with prompt cessation of seizures, resolution of anaemia, developmental progress, and prevention of development of severe and non-reversible manifestations. The remarkable recovery and prevention of advanced disease with prompt treatment, highlights the need to act immediately upon genetic diagnosis of a treatable disease. This further reinforces CAD deficiency as a treatable neurometabolic disorder and emphasises the need for a biomarker or genetic new born screening for early identification.
A Case of Recurrent Skin Abscesses: A Conundrum Solved after Obtaining a Thorough Sexual History
Authors: Diego P Peralta, Aymara Y Chang, Enrique Soto-Ruiz
Journal: Case Rep Infect Dis (2017)
MeSH terms: Case Reports

Background. Despite the improvement in patient-physician communication techniques, sexuality and sexual health continue to be challenging areas for discussion during a clinical encounter. Most people are not prepared to discuss sexual matters openly as it can be perceived as negative or inappropriate. Consequently, an incomplete health assessment can result in delayed diagnosis or misdiagnosis. Case Report. We present a 33-year-old woman who developed recurrent left breast abscesses. She required multiple incision and drainage procedures in the operating room followed by antimicrobial therapy. Although she always had an initial improvement with this approach, she continued to have recurrences and development of new abscesses in other body areas. The polymicrobial nature of her recurrences prompted an extensive and costly workup to determine the nature of her condition. The cause was finally elucidated when a thorough sexual history was obtained. Poor hygiene practices during her sexual encounters were considered the cause of her recurrent abscesses. After medical therapy and modification of her sexual practices, she has not developed new recurrences for more than two years. Conclusion. Discussions on sexuality and sexual health are important parts of any clinical encounter, yet frequently forgotten or avoided. Becoming aware of their importance would avoid delayed diagnosis or misdiagnosis.
Pregnancy after in vitro fertilization in an elderly primigravida with Shereshevsky-Turner Syndrome: A case report
Authors: Perizat Saparbaevna Sadykova, Sholpan Kuanyshbekovna Sarmuldayeva, Galina Kalievna Kausova, Elvira Shukenova, Linas Rovas
Journal: Int J Reprod Biomed (2023)
Keywords: hypogonadism, infertility, progesterone, pregnancy, turner syndrome
MeSH terms: Case Reports

Background:
Shereshevsky-Turner Syndrome is a chromosomal condition that affects females owing to full or partial missing of X-monosomy in all or part of the body's cells. Shereshevsky-Turner Syndrome is characterized by severe hormonal disorders and defects of the cardiovascular and urinary systems. With the advent of assisted reproductive technology (ART), pregnancy has become more accessible for this group of cases, often with donor eggs. In the available literature, it was not possible to find exact information during the time of selection of progestogen support, the duration of the appointment, and the term of withdrawal.
Case presentation:
This is the case of a 36-yr-old primigravid woman suffering from STs, mosaic karyotype comprising of 3 clones: 45X (69), 46XX (23), 47XXX (8), and 1000 interphase nuclei. In this case, we left high-maintenance doses of progesterone due to the application of ART and concomitant extragenital pathology, leading to a decrease in all functions of the placenta, including the endocrine. The woman was monitored before, during, and after the pregnancy. She was delivered at 37 wk and 6 days of gestation.
Conclusion:
ART increases the possibility of having a pregnancy and gestation in cases with a wide variety of genital and extragenital pathologies.
Acute Appendicitis: An Extracolonic Manifestation of Clostridium difficile Colitis
Authors: Ali Ridha, Shoaib M Safiullah, Sarah Al-Abayechi, Amin Ur Rehman Nadeem
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

The current report is the case of a 30-year-old male patient who presented with symptomatology suggestive of appendicitis. However, careful history-taking and laboratory tests led to the diagnosis of Clostridium difficile colitis, resulting in successful nonsurgical management of this patient. Although both appendicitis and C. difficile colitis are common conditions, they are rarely diagnosed concurrently. This is reflected by paucity of literature describing this manifestation. Given this current presentation, the authors contend that the manifestation of extracolonic colitis within the appendix is possibly underdiagnosed or misdiagnosed as an acute appendicitis and thus potentially results in unnecessary surgical intervention. This report reminds physicians to consider the medical approach to managing acute appendicitis given the possibility of underlying C. difficile colitis as the causative factor.
Left Bundle Pacing for Left Bundle Branch Block and Intermittent Third-Degree Atrioventricular Block in a MYH7 Mutation-Related Hypertrophic Cardiomyopathy With Restrictive Phenotype in a Child
Authors: Luyan Zhang, Xueying Cheng, Jinlong Chen, Ming Zhou, Tianwei Qian, Zhongman Zhang, Jie Yin, Han Zhang, Genyin Dai, Yuming Qin, Shiwei Yang
Journal: Front Pediatr (2020)
Keywords: myh7, conduction block, genetics, hypertrophic cardiomyopathy, left bundle pacing, restrictive phenotype
MeSH terms: Case Reports

Hypertrophic cardiomyopathy (HCM) is a group of myocardial diseases defined by cardiac hypertrophy which cannot be explained by secondary causes with a non-dilated left ventricle and preserved or increased ejection fraction. Sometimes it can be combined with restrictive cardiomyopathy. Here we describe a very rare case of a 12-year-old girl with non-obstructive hypertrophic cardiomyopathy accompanied by restrictive phenotype, complete left bundle branch block and intermittent third-degree atrioventricular block, who presented with recurrent syncope. Her father was also found to have hypertrophic cardiomyopathy and treated with implantable cardioverter defibrillator for ventricular tachycardia. Her younger brother is currently asymptomatic but echocardiogram showed hypertrophic cardiomyopathy. Genetic analysis identified a heterozygous missense mutation (c.2155C>T, p.R719W) of MYH7 in the proband girl, her father and her brother. The girl was treated with left bundle pacing and recovered well. The case we present further demonstrates the feasibility of left bundle pacing in children.
Persistent Left Superior Vena Cava: Implications of Surgical Management
Authors: Robin Boyer, Ramanjeet Sidhu, Aslan Ghandforoush, Theingi Win, Arash Heidari
Journal: J Investig Med High Impact Case Rep (2019)
Keywords: coronary, superior vena cava, surgical management, transplant
MeSH terms: Heart Defects, Congenital / diagnosis, Heart Defects, Congenital / surgery, Heart Failure / etiology, Vena Cava, Superior / abnormalities, Case Reports, Adult, Defibrillators, Implantable, Heart Transplantation, Humans, Incidental Findings, Male

Persistent left superior vena cava is the most common congenital anomaly of thoracic venous return, which results when the left anterior cardinal vein fails to regress. A 41-year-old African American male with a history of an unspecified childhood cardiac murmur presented to the emergency department with congestive heart failure exacerbation revealing an incidental finding of a persistent left superior vena cava. Ultimately, he required implantable cardioverter defibrillator placement and cardiac transplantation assessment. In the setting of advanced device placement or cardiac transplantation, a persistent left superior vena cava warrants several important clinical considerations at a center capable of addressing the possibility of a right-sided approach and transplantation irregularities.
Tuberculosis of the parotid gland: histology surprise
Authors: Noureddine Errami, Amine Benjelloun, Nessrine Tahtah, Bouchaib Hemmaoui, Ali Jahidi, Ismail Nakkabi, Mohamed Zalagh, Fouad Benariba
Journal: Pan Afr Med J (2015)
Keywords: tuberculosis, endemic countries, parotid gland
MeSH terms: Antitubercular Agents / therapeutic use, Parotid Diseases / diagnosis, Tuberculosis, Oral / diagnosis, Case Reports, Adult, Female, Humans, Parotid Diseases / drug therapy, Parotid Diseases / microbiology, Parotid Gland / microbiology, Parotid Gland / pathology, Treatment Outcome, Tuberculosis, Oral / drug therapy, Tuberculosis, Oral / pathology, Antitubercular Agents

The Parotid gland is rarely involved in tuberculosis, even in endemic countries. We report a case of a 26 year-old woman with no medical history, who presented with a swelling of the parotid lodge. Pathology performed after surgery found a tuberculous parotitis, and the patient received anti-tuberculous regimen with a satisfactory evolution. We discuss both diagnostic and therapeutic modalities for this infection.
Lipomatous Hypertrophy of the Atrial Septum in a Patient Undergoing Coronary Artery Bypass Surgery
Authors: Thomas Strecker, Michael Weyand, Abbas Agaimy
Journal: Case Rep Pathol (2016)

Background. Lipomatous hypertrophy of the atrial septum (LHAS) is a rare entity characterized by mass-forming deposition of fatty tissue within the atrial septum. To date, <300 cases have been reported; many of them were autopsy findings. The clinical presentation of LHAS varies from incidental asymptomatic mass (most frequent form) to severe life-threatening cardiovascular complications necessitating emergency cardiac surgery. Case Presentation. Here, we present the successful surgical resection of such a massive LHAS which was found incidentally on preoperative investigation of a 71-year-old patient with progressive coronary heart disease. Histology confirmed the diagnosis of lipomatous hypertrophy of the atrial septum. Conclusions. The described case report illustrates an unusual example of LHAS in a patient undergoing a planned coronary artery bypass surgery. In this case, surgical intervention was justified to avoid later outflow obstructions.