OpenMed/multicare-articles huggingface dataset:
Primary breast lymphoma: A mimic of inflammatory breast cancer
Authors: Ana Melo, Sílvia Silva, Cátia Ferreira, Ricardo Pereira, Ana Esteves, Rita Abreu Marques, Herculano Moreira, Paulo Avelar
Journal: Int J Surg Case Rep (2018)
Keywords: breast malignancy, case report, combined therapy, primary breast lymphoma

Introduction:
Primary breast lymphoma (PBL) is a rare disease accounting for 0.04-0.5% of all breast malignancies.
Presentation of case:
This article reports a clinical case of a 81-year-old woman with a history of right breast erythema and edema associated to breast pain, with over two weeks duration. Physical examination demonstrated mammary asymmetry and inflammatory signs with orange peel skin. She had the right upper limb swollen and palpable axillar and supraclavicular lymph nodes. The principal suspicion was an inflammatory breast cancer. Imaging was unspecific. Core needle biopsy of an axillary lymph node and of the breast mass identified morphological and immunophenotypic features consistent with diagnosis of primary non-Hodgkin DLBCL. Patient was guided by Hematology.
Discussion:
The clinical and imaging ﬁndings in breast lymphoma can mimic those of breast carcinoma. Sometimes, PBL presentation is suggestive of Inflammatory breast cancer. Diagnosis depends on adequate tissue sampling for histology examination and immunophenotyping. The therapeutic management of PBL is controversial and is not clearly established, but many studies support that it is not a surgical disease and can be treated successfully with combined chemotherapy and radiotherapy.
Conclusion:
Breast lymphoma must be considered in the differential diagnosis of a breast lump, even in the presence of cutaneous inflammatory changes. PBL can be treated successfully with combined therapy.
Giant squamous cell carcinomas of the shoulder
Authors: Mounir Yahyaoui, Najib Abbassi, Abdelhafid Derfoufi, Abdelkarim Daoudi, Omar Agoumi, Hicham Yacoubi, Abdeljaouad Najib, Badr Serji, Tijjani Elharroudi, Nabil Mouzouri, Siham Dikhaye, Nada Zizi, Hanane Hadjkacem
Journal: Pan Afr Med J (2020)
Keywords: squamous cell carcinomas, giant, reconstruction, resection, shoulder
MeSH terms: Carcinoma, Squamous Cell / diagnosis, Plastic Surgery Procedures / methods, Shoulder / pathology, Case Reports, Carcinoma, Squamous Cell / pathology, Carcinoma, Squamous Cell / therapy, Combined Modality Therapy, Female, Humans, Middle Aged, Surgical Flaps

Giant squamous cell carcinomas (SCC) larger than 5 cm in diameter are uncommon; there is no guideline on the size of an SCC that is considered giant. Treatment may be difficult with the need for large tissue resections and complex surgical reconstruction. We report a rare case of giant squamous cell carcinoma of the shoulder attached to deep anatomic planes. The entire mass was removed, resulting in a large defect that was repaired with myocutaneous flap rotation of the latissimus dorsi. Three courses of radiotherapy were performed after surgery. Fifteen months after the operation, the patient is well and working without any local recurrence and metastasis.
Not All Orbitopathy Is Graves': Discussion of Cases and Review of Literature
Authors: Neeraja Boddu, Maliha Jumani, Vibhor Wadhwa, Gitanjali Bajaj, Fred Faas
Journal: Front Endocrinol (Lausanne) (2017)
Keywords: graves’ orbitopathy, differential of thyroid-associated orbitopathy, orbital lymphoma, orbitopathy, sarcoid orbitopathy
MeSH terms: Case Reports

Introduction:
Graves' orbitopathy is the extra thyroidal manifestation of Graves' disease and the most common cause of exophthalmos. It is also known as thyroid-associated orbitopathy (TAO) as it occasionally occurs in euthyroid or hypothyroid patients with chronic thyroiditis. 5% of patients with Graves' orbitopathy can be euthyroid or hypothyroid as they have low titers of anti-thyrotropin-receptor antibodies, which are difficult to detect in some assays. Orbitopathy has also been seen in a small percentage of patients with Hashimotos thyroiditis. The eye involvement in Graves' is frequently bilateral and symmetric. These patients pose few diagnostic difficulties when the ocular findings occur concomitantly with the thyroid disease. However, when unilateral and asymmetric ocular findings occur with normal or mildly abnormal thyroid function tests, alternate etiologies should also be pursued. We aim to discuss some conditions like sarcoidosis, lymphoma, orbital pseudotumor, and orbital malignancy that mimic TAO.
Cases:
Three patients were referred to us with concern for Graves' orbitopathy. After further work-up, we diagnosed the first patient with specific orbital myositis from sarcoidosis. Our second patient had CD10-positive B-cell lymphoma. Our third patient had orbitopathy likely secondary to Hashimotos or orbital pseudotumor.
Conclusion:
Our cases and discussion describe some other conditions that clinically mimic TAO and the importance of pursuing further work-up for accurate diagnosis when presentation of orbitopathy is atypical.
Unilateral simultaneous optic nerve and choroidal infiltration - unusual presentation of metastatic disease in breast carcinoma
Authors: Poninder Kumar, Ashok Kumar, Srujana Dubakka, Jaya Kaushik, Mohini Agrawal
Journal: GMS Ophthalmol Cases (2021)
MeSH terms: Case Reports

Breast carcinoma metastasis can involve any ocular structures, but involvement of the optic nerve is extremely rare. Choroidal metastasis is usually multifocal as well as bilateral and occurs late. We report an unusual initial presentation of metastasis from breast cancer; unilateral infiltrative optic neuropathy with concurrent choroid metastatic deposits in an adequately treated middle-aged female. Our present case, wherein for the first time in the literature, we illustrated unilateral infiltrative optic neuropathy and choroidal metastatic deposits secondary to breast carcinoma, will increase our knowledge about the various potential ocular presentations of this relatively common malignant disease.
Isolated Cranial Nerve-III Palsy Secondary to Perimesencephalic Subarachnoid Hemorrhage
Authors: Justin R Abbatemarco, Hussam A Yacoub
Journal: Case Rep Neurol Med (2016)

We describe isolated cranial nerve-III palsy as a rare clinical finding in a patient with perimesencephalic subarachnoid hemorrhage. In this unusual case, the patient presented with complete cranial nerve-III palsy including ptosis and pupillary involvement. Initial studies revealed subarachnoid hemorrhage in the perimesencephalic, prepontine, and interpeduncular cisterns. Angiographic studies were negative for an intracranial aneurysm. The patient's neurological deficits improved with no residual deficits on follow-up several months after initial presentation. Our case report supports the notion that patients with perimesencephalic subarachnoid hemorrhage have an excellent prognosis. Our report further adds a case of isolated cranial nerve-III palsy as a rare initial presentation of this type of bleeding, adding to the limited body of the literature.
Restoration of fertility after removal of extrauterine mirena coil: a case report and review of the literature
Authors: Smriti R C Bhatta, Radwan Faraj
Journal: Case Rep Obstet Gynecol (2011)
MeSH terms: Case Reports

We present the case of a 27-year-old lady who was seen in the infertility clinic with a history of secondary infertility of a one-year duration. She had a hysteroscopy and Mirena insertion for heavy periods. Coil strings were not found by the GP during first coil check six weeks after insertion. A pelvic ultrasound scan did not show any coil, and it was not investigated further with a possible diagnosis of coil expulsion made. One year following that, she was seen in the infertility clinic. Initial investigations revealed anovulation, and HSG located the coil to be extrauterine. Mirena was removed laparoscopically, and a month following the removal she conceived. She is currently pregnant. This case highlights the effect of extrauterine mirena coils on fertility by possibly causing higher plasma levels of levonorgesterol and resulting suppression of ovulation. Laparoscopic removal of mirena coil can help in restoration of fertility.
Case report: Acute ischemic stroke caused by intracranial artery dissection in a patient with skull fractures
Authors: Bo Zheng, XiaoLan Luo, JiangHao Zhou, XueQiong Huang, MaoXia Li, Hui Zheng, YiPing Yuan, Jian Wang
Journal: Front Neurol (2022)
Keywords: acute ischemic stroke, blunt cerebrovascular injuries, intracranial artery dissection, middle cerebral artery dissection, skull fractures
MeSH terms: Case Reports

The intracranial artery dissection (IAD) is an uncommon but life-threatening disease. The IAD would develop a significant cerebral infarction due to unrecognized contrecoup brain injury. We report a 53-year-old man fell to develop blunt cerebrovascular injuries (BCVIs) more than 2 months ago. During his rehabilitation, he often had a transient left headache and underwent short-term right limb weakness twice, but he did not care. He was hospitalized again because of suffering right limb weakness for more than 4 h. The brain computed tomography angiography (CTA) showed subtotal occlusion of the left middle cerebral artery M1 segment, and the vascular morphology displayed the IAD. The patient was then treated with balloon dilation and a self-expanding stent. This case highlights that IAD may show delayed onset with no initial typical symptom. By early detecting of abnormal signs and symptoms, serious traumatic brain injury may be avoided.
Candida albicans Osteomyelitis Pubis: The Possible Pathogenic Role of Pelvic Irradiation
Authors: Cristiana Iacuzzo, Jacopo Monticelli
Journal: Case Rep Orthop (2017)
MeSH terms: Case Reports

Radiation to the pelvis, mainly directed against either prostatic or gynecologic cancers, is burdened by a lot of complications. The genitourinary tract is most frequently involved, presenting with bladder irritation, incontinence, and fertility disorders. However, side effects of radiation can also affect the bone, usually causing an osteolytic process which deteriorates the bone structure and leads to fractures, avascular necrosis, and other pathological insults. Here, we describe a case of Candida albicans osteomyelitis of the pubic symphysis as late complication of pelvic radiotherapy performed against prostate cancer.
Two rare cases of acute myeloid leukemia with t(8;16)(p11.2;p13.3) and 1q duplication: case presentation and literature review
Authors: Meng Liu, Yuan Ren, Xianfu Wang, Xianglan Lu, Ming Li, Young Mi Kim, Shibo Li, Lijun Zhang
Journal: Mol Cytogenet (2020)
Keywords: 1q duplication, acute myeloid leukemia, prognostic factor, t(8, 16)(p112, p133)

Background:
Acute myeloid leukemia (AML) is a complex hematological disease characterized by genetic and clinical heterogeneity. The identification and understanding of chromosomal abnormalities are important for the diagnosis and management of AML patients. Compared with recurrent chromosomal translocations in AML, t(8;16)(p11.2;p13.3) can be found in any age group but is very rare and typically associated with poor prognosis.
Methods:
Conventional cytogenetic studies were performed among 1,824 AML patients recorded in our oncology database over the last 20 years. Fluorescence in situ hybridization (FISH) was carried out to detect the translocation fusion. Array comparative genome hybridization (aCGH) was carried out to further characterize the duplication of chromosomes.
Results:
We identified three AML patients with t(8;16)(p11.2;p13.3) by chromosome analysis. Two of the three patients, who harbored an additional 1q duplication, were detected by FISH and aCGH. aCGH characterized a 46.7 Mb and 49.9 Mb gain in chromosome 1 at band q32.1q44 separately in these two patients. One patient achieved complete remission (CR) but relapsed 3 months later. The other patient never experienced CR and died 2 years after diagnosis.
Conclusion:
A 1q duplication was detected in two of three AML patients with t(8;16)(p11.2;p13.3), suggesting that 1q duplication can be a recurrent event in AML patients with t(8;16). In concert with the findings of previous studies on similar patients, our work suggests that 1q duplication may also be an unfavorable prognostic factor of the disease.
A Case of a Spinal Extradural Arachnoid Cyst
Authors: Yousuke Kojimahara, Shintaro Tsuge, Keiji Hasegawa, Katsunori Fukutake, Kazumasa Nakamura, Akihito Wada, Hiroshi Takahashi
Journal: Case Rep Orthop (2019)
MeSH terms: Case Reports

The patient was a 49-year-old woman with a chief complaint of hip and buttock pain that had persisted for 3 years. She visited our hospital for aggravation of the pain. Percussion tenderness of the spinous process was observed and a T1-low, T2-high cystic lesion was detected on the dorsal side of the dural canal at the 12th thoracic vertebral level on MRI performed by a previous physician. Plane CT showed severe scalloping at the same level. During laminectomy for the 11th and 12th thoracic vertebrae, a cystic lesion of about 60 × 25 mm was noted on the dorsal side of the dural canal, with a communication pathway with the cyst present near the left 12th nerve root bifurcation. This pathway was ligated and the cyst was excised. The histopathological diagnosis was an arachnoid cyst. Pain improved after surgery, and as of 10 months after surgery, the cystic lesion has not recurred. A spinal extradural arachnoid cyst (SEAC) is a relatively rare disease. This case shows that surgical ligation of a communicating tract and cystectomy are necessary and contrast-enhanced CT was useful for the identification of the position of the communication pathway before surgery.
On the self-regulation of sport practice: Moving the narrative from theory and assessment toward practice
Authors: Bradley W Young, Stuart G Wilson, Sharleen Hoar, Lisa Bain, Malgorzata Siekańska, Joseph Baker
Journal: Front Psychol (2023)
Keywords: applied survey use, deliberate practice, psychology of practice, self-regulated learning, translating theory-to-practice

This paper reviews theoretical developments specific to applied research around the "psychology of practice" in skill acquisition settings, which we argue is under-considered in applied sport psychology. Centered upon the Self-Regulation of Sport Practice Survey (SRSP), we explain how self-regulated learning conceptually underpins this survey and review recent data supporting its empirical validation for gauging athletes' psychological processes in relation to sport practice. This paper alternates between a review of applied research on self-regulated sport practice and new data analyses to: (a) show how scores on the SRSP combine to determine an expert practice advantage and (b) illustrate the large scope of self-organized or athlete-led time to which SRSP processes may apply. At this stage, the SRSP has been established as a reliable and valid tool in the empirical, theoretical domain. In order to move the narrative from theory and assessment toward applied practice, we present evidence to propose that it has relevance as a dialogue tool for fostering meaningful discussions between athletes and sport psychology consultants. We review initial case study insights on how the SRSP could be located in consultation in professional practice, propose initial considerations for its practical use and invite practitioners to examine its utility in applied settings.
Severe ocular sequelae of congenital toxoplasmosis: huge macular scar
Authors: Fadoua Zahir, Meriem Abdellaoui, Samar Younes, Idriss A Benatiya, Hicham Tahri
Journal: Pan Afr Med J (2015)
Keywords: congenital toxoplasmosis, retinochoroiditis, sequelae
MeSH terms: Chorioretinitis / parasitology, Cicatrix / parasitology, Toxoplasmosis, Congenital / complications, Toxoplasmosis, Ocular / complications, Case Reports, Child, Preschool, Chorioretinitis / diagnosis, Cicatrix / etiology, Humans, Male, Toxoplasmosis, Congenital / diagnosis, Toxoplasmosis, Ocular / congenital, Toxoplasmosis, Ocular / diagnosis

Retinochoroiditis is the most common ocular manifestation of congenital toxoplasmosis, but other associated ophthalmological pathologies can also occur. Ophthalmologists are rarely able to distinguish between toxoplasmic retinochoroiditis due to infection acquired before or after birth, unless other clinical or serological indications are present. This article reports a case of a 3-year-old boy with abnormalities suggestive of congenital toxoplasmosis. The clinical and complementary examinations are discussed. The education of pregnant women is crucial for the prevention of congenital toxoplasmosis. Awareness of antenatal and postnatal presenting signs and symptoms is important for clinicians, because early diagnosis and treatment may minimize sequelae. Untreated, the majority of affected infants will develop chorioretinitis, deafness and/or neurological symptoms.
Single Sitting Surgical Treatment of Generalized Aggressive Periodontitis Using GTR Technique and Immediate Implant Placement with 10-Year Follow-Up
Authors: Fatme Mouchref Hamasni, Fady El Hajj, Rima Abdallah
Journal: Case Rep Dent (2018)
MeSH terms: Case Reports

This case report exhibits a patient with generalized aggressive periodontitis who has been under maintenance for the past 12 years after being surgically treated in a single sitting and restored with dental implants. A 41-year-old systemically healthy male patient presented complaining of lower anterior teeth mobility and pain in the upper right quadrant. After clinical and radiographic examination, the upper right molars and lower anterior incisors were deemed unrestorable. Covered by doxycycline, the patient received a nonsurgical periodontal treatment. Three weeks later, teeth extraction, immediate implant placement, immediate nonloading provisional prosthesis, and a guided tissue regeneration were performed at indicated areas in a single sitting. The clinical decisions were based on patient compliance, the status of the existing periodontal tissues, and the prognosis of the remaining teeth. During the 12-year follow-up period, no residual pockets were observed and there was no exacerbation of the inflammatory condition. Marginal bone stability is present on all implants. For aggressive periodontal disease, a high risk of relapse as well as limited success and survival of dental implants should be considered. This case shows proper containment of the disease based on appropriate treatment planning and a strict maintenance program.
Cryoablation for Ventricular Tachycardia Originating from Anterior Papillary Muscle of Left Ventricle Guided by Intracardiac Echocardiography
Authors: Ibrahim Marai, Nizar Andria, Osnat Gurevitz
Journal: Case Rep Cardiol (2017)
MeSH terms: Case Reports

Papillary muscles (PMs) were reported to be origin of ventricular arrhythmia (VA). Radiofrequency (RF) ablation was reported to be acutely effective in eliminating VA. However, the recurrence rate is high. Recently, cryoablation guided by intracardiac echocardiography, 3-dimensional mapping system, and image integration was introduced as alternative strategy for this challenging ablation. We present a case of ventricular tachycardia originating from anterior PM of left ventricle treated by cryoablation guided only by intracardiac echocardiography.
Maxillary tuberosity reconstruction with transport distraction osteogenesis
Authors: F Ugurlu, B Basel, B Cem Sener, A Sertgöz
Journal: Case Rep Dent (2012)
MeSH terms: Case Reports

Severe bone loss due to pathology in the maxillary tuberosity region is a challenging problem both surgically and prosthetically. Large bone grafts have a poor survival rate due to the delicate bony architecture in this area and presence of the maxillary sinus. Our case presentation describes a new technique for reconstructing severe bony defect in the maxillary tuberosity with horizontal distraction osteogenesis in a 45-year-old man. A 4 × 6 × 3 cm cyst was discovered in the left maxillary molar region and enucleated. Three months postoperatively, the area had a severe bone defect extending to the zygomatic buttress superiorly and hamular notch posteriorly. Three months later, a bone segment including the right upper second premolar was osteotomised and distracted horizontally. The bone segment was distracted 15 mm distally. After consolidation, implants were placed when the distractor was removed. A fixed denture was loaded over the implants after 3 months. Complete alveolar bone loss extending to the cranial base can be reconstructed with transport distraction osteogenesis. Distalisation of the alveolar bone segment adjacent to the bony defect is an easy method for reconstructing such severe defects.
Pseudohypoparathyroidism during pregnancy and the postpartum period: A case series of five patients
Authors: Jia-Jia Wang, Yi Yang, Ya-Bing Wang, An Song, Yan Jiang, Mei Li, Wei-Bo Xia, Yan-Ping Liu, Ou Wang, Xiao-Ping Xing
Journal: Front Endocrinol (Lausanne) (2022)
Keywords: lactation, pregnancy, pseudohypoparathyroidism, serum pth, serum calcium, treatment
MeSH terms: Bone Density Conservation Agents, Pseudohypoparathyroidism / complications, Pseudohypoparathyroidism / drug therapy, Research Support, Non-U.S. Gov't, Calcium, Cesarean Section, Female, Humans, Infant, Newborn, Postpartum Period, Pregnancy, Retrospective Studies, Calcium, Bone Density Conservation Agents

Objectives:
Pseudohypoparathyroidism (PHP) is a rare disease, especially when combined with pregnancy. We aimed to explore the changes in serum calcium/parathyroid hormone (PTH) level and medical treatment in a case series of PHP during pregnancy and the postpartum period.
Methods:
A total of five PHP patients with six pregnancies were enrolled. The classification of PHP was based on (epi)genetic analysis. Clinical characteristics, biochemical indices, and treatment strategies before, during, and after pregnancy were retrospectively collected.
Results:
All patients received calcium and vitamin D agents with nearly normal serum calcium before pregnancy except patient 2 who was found hypocalcemic during gestation. All patients chose Cesarean section, and one suffered preterm delivery due to oligoamnios. The neonatal birth weight ranged from 2,250 to 4,300 g, and all neonates were free of hypocalcemia-related symptoms. The change in calcium metabolism was inconsistent including stable, improved, or worsened during pregnancy. Serum PTH level remained low in the first two trimesters in patients with stable and improved conditions while increased in the last two trimesters in patients with a worsened condition. Serum calcium changed inconsistently while PTH increased consistently during lactation. For patients who did not breastfeed, calcium homeostasis improved after delivery.
Conclusion:
Calcium homeostasis and medicine dosage changed differently in PHP patients during pregnancy and lactation. However, most patients had good pregnancy outcomes. Serum PTH levels might predict changes in calcium metabolism during pregnancy.