OpenMed/multicare-articles huggingface dataset:
Factors in healthcare violence in care of pregnancy termination cases: A case study
Authors: Chunxiang Qin, Wei-Ti Chen, Yunlong Deng, Xinchun Liu, Xiaoxia Wu, Mei Sun, Ni Gong, Siyuan Tang
Journal: PLoS One (2018)
MeSH terms: Health Personnel / psychology, Quality of Health Care / statistics & numerical data, Workplace Violence / psychology, Research Support, Non-U.S. Gov't, Aborted Fetus, Abortion, Induced / psychology, China / epidemiology, Female, Humans, Interview, Psychological, Pregnancy, Pregnant Women / psychology

Background:
Workplace violence is a widely-reported phenomenon among healthcare providers and negatively affects quality of care and treatment. This study aims to understand the potential factors related to HCV through the experiences of women who have undergone a pregnancy termination due to fetal anomaly.
Methods:
Qualitative interview was used to collect data in this case study. Forty-one pregnant women who decided to terminate their pregnancy due to fetal anomaly were recruited from four Chinese hospital facilities, including three general hospitals and one specialty hospital in Changsha, Hunan, China. In-depth interviews were conducted from May to September 2017. Content analysis was used to analyze the data.
Results:
Several potential factors related to violence in healthcare facilities were identified, including preventive factors, which possibly relieve healthcare violence; and negative experiences, which potentially related to healthcare violence. Preventive factors include healthcare providers gaining patient trust with detailed observation, expressing patient-centered care through discreet behavior, and showing patience and professionalism. Factors related to violence include busy work schedules, hurried visits, mechanized process, patients' scant medical knowledge and mental distress.
Conclusions:
This study highlights potential factors related to healthcare violence. The results will be submitted to the Chinese government's policy making department in order to improve the healthcare system. We also suggest several important strategies to prevent HCV in a healthcare setting, both in China and globally.
Successful management of pregnancy in an African woman with Klippel Trenaunay syndrome
Authors: Jean Dupont Ngowa Kemfang, Walter Pisoh Dobgima, Regine Mbouopda Motzebo, Anny Ngassam, Marcus Fokou, Jean-Marie Kasia
Journal: Pan Afr Med J (2013)
Keywords: klippel trenaunay syndrome, yaounde, pregnancy
MeSH terms: Klippel-Trenaunay-Weber Syndrome / therapy, Pregnancy Complications, Cardiovascular / therapy, Case Reports, Adult, Cameroon, Female, Humans, Klippel-Trenaunay-Weber Syndrome / complications, Pregnancy, Treatment Outcome, Varicose Veins / complications, Varicose Veins / therapy

Klippel Trenaunay syndrome (KTS) is a rare congenital disease characterized by a triad of cutaneous hemangioma, varicose veins and bone or soft tissue hypertrophy. Cases of pregnancy complicated by KTS are rare. There is an increased risk of thrombo-embolic disease and hemorrhage during pregnancy. Both obstetric and anesthetic management of KTS in pregnancy can be rather complicated. We present a successful management of pregnancy in an African woman with KTS at Yaounde General Hospital, Cameroon.
Repair of Posterior Vaginal Wall Defect Using Biologic Graft for Stage III-POP-Q Pelvic Organ Prolapse in a Patient with History of a J-Pouch
Authors: Ali Azadi, Stephanie Casey, Paravasthu Ramanujam, Darya Tehranchi, Donald Ostergard
Journal: Case Rep Obstet Gynecol (2020)
MeSH terms: Case Reports

Surgical correction is considered in women with symptomatic pelvic organ prolapse (POP). There is an expected increase in the prevalence of surgical correction due to an aging population within the United States. Individuals with previous colorectal surgery present a unique challenge considering the changes in pelvic anatomy. This case discusses the challenges of posterior colporrhaphy in a patient with previous, remote J-pouch surgery. In traditional posterior colporrhaphy, randomized controlled trials have not shown any benefit of graft augmentation (Maher, 2016). However, the utilization of a biologic graft to improve anatomical correction is discussed in this unique case. Short term anatomical success was obtained without immediate complications in the postoperative period. In a patient with a history of ulcerative colitis with colorectal resection and a J-pouch, surgery can be challenging due to alterations of pelvic anatomy. Modification of the standard surgical approach may be required to achieve success.
Cause Analysis of an Infection in Facelift Surgery Due to Mycobacterium chelonae
Authors: Marie Decalonne, Emmanuel Lecorche, Estelle Hau, Agnès Petiteau, Célia Moreau, Odile Milan, Philipe Lanotte, Laurent Mereghetti, Emmanuelle Cambau, Nathalie van der Mee-Marquet
Journal: Front Med (Lausanne) (2019)
Keywords: mycobacterium chelonae, wgs, post-surgical infection, showering, tap water
MeSH terms: Case Reports

We report a post-facelift infection due to Mycobacterium chelonae. An environmental strain recovered from the water supply network of the surgical clinic and the clinical strains were considered non-differentiable using whole genome sequencing. After the unhealed wound's exposure to M. chelonae while showering early at the clinic after surgery, a lasting exposure of the colonized wound to the warm and moist working conditions of a bakery may have been favorable to the infection's development.
Primary mature adrenal teratoma in infant
Authors: Siham El Haddad, Laila Hessissen, Maria El Kababri, Najat Lamalmi, Mounir Kisra, Nazik Allali, Latifa Chat
Journal: Pan Afr Med J (2020)
Keywords: primary mature, retroperitoneum, teratoma
MeSH terms: Adrenal Gland Neoplasms / diagnostic imaging, Liver Neoplasms / diagnostic imaging, Retroperitoneal Neoplasms / diagnostic imaging, Teratoma / diagnostic imaging, Case Reports, Adrenal Gland Neoplasms / pathology, Adrenal Gland Neoplasms / surgery, Female, Humans, Infant, Liver Neoplasms / secondary, Magnetic Resonance Imaging, Retroperitoneal Neoplasms / pathology, Retroperitoneal Neoplasms / surgery, Teratoma / pathology, Teratoma / surgery, Tomography, X-Ray Computed

Teratomas are neoplasms of the embryonic tissues that typically arise in the gonadal and sacrococcygeal regions. Primary adrenal teratoma are extremely rare and only few cases were published in literature. Teratomas contain more than one embryonic germ cell layer, mostly elements derived from ectoderm and least frequently from endoderm. Though these tumors are mostly benign, malignant transformation may occur. Treatment includes surgical removal. We report a rare case of a primary mature retroperitoneal teratoma in an infant with liver metastasis. Imaging modality CT and MRI were useful in diagnosis. The diagnostic and therapeutic challenges of dealing with such a case have been discussed and the literature reviewed.
Development of Focal Nodular Hyperplasia after Cyclophosphamide-Based Chemotherapy in a Patient with Breast Cancer
Authors: Dan-Qing Xue, Lan Yang
Journal: Case Reports Hepatol (2018)
MeSH terms: Case Reports

Focal nodular hyperplasia (FNH) is the second most common liver cell-derived benign tumor. It is postulated that chemotherapy-induced hepatic circulatory abnormalities, like sinusoidal obstruction syndrome (SOS), could lead to the development of FNH. Cyclophosphamide was also reported to induce SOS in a synergistic effect with total body irradiation. However, none of cyclophosphamide-related FNH had ever been reported before. In this case report, we present a female patient who was treated with neoadjuvant chemotherapy of cyclophosphamide (500mg/m2)-docetaxel (75mg/m2)-pharmorubicin (90mg/m2) regimen every 3 weeks for breast cancer developed FNH after 4 courses of treatment. The patient had no chronic liver disease, no history of smoking, drinking, or medication use. The chronological correlation between the chemotherapy and the appearance of the FNH suggested a cause-effect association. Therefore, this is the first case report about development of FNH after cyclophosphamide-based chemotherapy. Taking into account the frequency of breast cancer, it is instructive to recognize such observation of FNH in the context to make the differential diagnosis with hepatic metastasis.
A Case of Pulmonary Infarction Resembling Pneumonia during Immunosuppressive Treatment for Rheumatoid Arthritis
Authors: Toshiki Kido, Koichiro Shinoda, Kazuyuki Tobe
Journal: Case Rep Rheumatol (2021)
MeSH terms: Case Reports

A 67-year-old woman with rheumatoid arthritis (RA) presented with fever and dyspnea. Chest radiography and computed tomography (CT) revealed pulmonary infiltrates with ground-glass opacities. We considered bacterial or pneumocystis pneumonia because she was immunocompromised due to RA treatment. However, she had tachycardia and elevated D-dimer levels. We performed contrast-enhanced CT and subsequently diagnosed her with pulmonary embolism (PE). Though PE is not usually accompanied by parenchymal pulmonary shadows, pulmonary infarction may cause pulmonary infiltrates that can be mistaken for pneumonia. As RA is a thrombophilic disease, clinicians should be aware of PE and pneumonia as differential diagnoses in such patients.
Uterine cervix metastasis from a sigmoid adenocarcinoma: a rare presentation of an uncommon tumor
Authors: Soufiane Berhili, Basma El Khannoussi, Selma Kadiri, Imane Mezouri, Amine Bazine, Asmae Touil, Imane El Khiyat, Tayeb Kebdani, Noureddine Benjaafar
Journal: Gynecol Oncol Res Pract (2014)
Keywords: adenocarcinoma, immunohistochemistry, metastasis, sigmoid cancer, uterine cervix
MeSH terms: Case Reports

Metastatic carcinoma to the uterine cervix from colorectal cancer, through haematogenous or lymphatic spread, is extremely rare. We report the case of a 59 year old woman in whom cervical metastasis was diagnosed after 13 months of follow-up for a sigmoid adenocarcinoma, confirmed by immunohistochemical study, with a review of the literature. This case illustrates that abnormal gynecologic symptoms can reveal a disease progression on patients who suffer colorectal cancer.
Symptomatic Bochdalek Hernia in Pregnancy: A Rare Case Report
Authors: Selçuk Yetkinel, Çağhan Pekşen, Remzi Kızıltan
Journal: Case Rep Surg (2017)
MeSH terms: Case Reports

Introduction:
Symptomatic Bochdalek hernia in pregnancy is quite rare. To the best of our knowledge, there are a total of 44 cases reported in the literature between 1959 and 2016 (Hernández-Aragon et al., 2015; Koca et al., 2016). Difficulty and delay in diagnosis may lead to life-threatening complications.
Case report:
We report a case of Bochdalek hernia during the 30 gestational weeks' pregnancy in whom pregnancy continued after surgical repair which resulted in term birth.
Discussion:
Bochdalek hernia is diagnosed with an incidence of 1 in 2200-12500 live births, while symptomatic diaphragm hernia is much less in adults. The actual incidence of diaphragmatic hernias during pregnancy is still unknown. Symptoms may include abdominal distension, recurrent abdominal pain, nausea, vomiting, inability to defecate, dyspnea, and chest pain. The patient with diaphragmatic hernia may be asymptomatic until the late weeks of gestation, as in our case, or herniation may occur during advanced gestational weeks with increased intraabdominal pressure.
Conclusion:
In conclusion, diagnosis of the diaphragm hernia during pregnancy is very rare. Diagnosis is rarer in symptomatic patients due to its rarity and the duration of diagnosis may, therefore, be delayed. Diaphragm hernia should be kept in mind in symptomatic patients due to its high maternal and fetal mortality rates.
Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion
Authors: Ashley Griswold, Briana Tully, Kenneth Katz, Gillian Beauchamp, Matthew Cook, Robert Cannon
Journal: Case Rep Emerg Med (2019)
MeSH terms: Case Reports

Lamotrigine is a new generation antiepileptic which blocks sodium channels and can cause significant toxicity in overdose. A case of a three-year-old child who suffered a seizure and required endotracheal intubation after accidental lamotrigine ingestion is presented. The lamotrigine concentration measured 23.2 mcg/mL which is the highest reported after accidental pediatric exposure. A review of the literature regarding pediatric lamotrigine poisoning is also included.
Unusual Urologic Metastasis From Gastrointestinal Cancers: A Compilation of Case Reports and Literature Review
Authors: Ana Barbosa, Vânia Grenha, Ilda Faustino, Camila Coutinho
Journal: Cureus (2023)
Keywords: bladder metastasis, clinical case, gastrointestinal cancer, haematuria, penile metastasis
MeSH terms: Case Reports

Gastrointestinal cancers are highly prevalent around the world. In the metastatic setting, the most usual sites for metastases are the liver, lymph nodes, peritoneum, and lung. Urologic metastases are very rare. We report a case series of three patients with gastrointestinal tumours in different topographies (stomach, colon, and rectum) with urological metastases. In all cases, the patients were initially treated with curative intent. Two of the patients presented with bladder metastases, and the third had penile metastases in addition to pulmonary metastases. Haematuria was the most common symptom at presentation. One of the patients had a good overall survival and is still undergoing palliative intent chemotherapy. In the literature, there are few reported cases of urological metastases from gastrointestinal cancers, and that is the aim of this publication.
Pathological complete response after neoadjuvant immunotherapy combined with chemotherapy in pediatric rectal carcinoma: A case report
Authors: Xiaomeng Cao, Jianwei Luo, Baoyin Zhao, Hongjiang Fu, Wendi Kang
Journal: Front Immunol (2022)
Keywords: immune checkpoint inhibitors, microsatellite instability-high, neoadjuvant immunotherapy, pathological complete response, pediatric colorectal cancer
MeSH terms: Carcinoma, Colorectal Neoplasms / genetics, Rectal Neoplasms / therapy, Case Reports, Adult, Child, Humans, Immunotherapy, Male, Neoadjuvant Therapy / methods

Background:
Pediatric colorectal carcinoma (PCRC) is a rare non-embryonal tumor with an incidence of 0.1% to 1% of adults. Immune checkpoint inhibitors (ICIs) targeting programmed death-1 (PD-1) have shown significant efficacy in defective mismatch repair/Microsatellite instability-high (dMMR/MSI-H) metastatic CRC (mCRC). Although several studies have reported neoadjuvant immunotherapy (NIT) in MSI-H/dMMR non-mCRC patients, not all patients achieved pathological complete remission (pCR). There are differences between PCRC and adult colorectal carcinoma (CRC), and the role of NIT in PCRC remains to be further defined.
Case presentation:
We report the case of a 12-year-old child who was admitted to the hospital with abdominal pain and vomiting for more than 3 months. The child's diagnosis was difficult and complex. He was initially diagnosed with intestinal obstruction, eventually diagnosed with a rare PCRC and identified as locally advanced colorectal cancer (LACRC) with genetic sequencing results showing MSI-H. After a thorough evaluation by clinicians, he received 4 cycles of Camrelizumab (anti-PD-1 antibody) + CapeOx (capecitabine and oxaliplatin) NIT combination chemotherapy. Repeat imaging and all tumor markers were unremarkable, and R0 resection was achieved. Postoperative pathology showed a tumor regression grade (TRG) of 0 grade determined as pCR. Postoperative review has not shown any recurrence or metastasis to date and the prognosis is good.
Conclusion:
PCRC should improve the diagnostic efficiency to prevent misdiagnosis and miss the best time for treatment. NIT and or chemotherapy can be a reasonable and effective treatment option for dMMR/MSI-H locally advanced PCRC. Our report provides some support and evidence for neoadjuvant immunotherapy for locally advanced PCRC, while highlighting the importance of preoperative detection of microsatellite status for locally advanced PCRC.
Intrahepatic Type II Gall Bladder Perforation Secondary to Acute Acalculous Cholecystitis
Authors: Vimaleswaran Koculen, Umesh Jayarajah, Anil P Ambawatte
Journal: Case Rep Surg (2020)
MeSH terms: Case Reports

Gall bladder perforation is a rare but serious complication of acute cholecystitis. Gall bladder perforations commonly occur in patients with comorbidities and in association with gall stones. We report a rare occurrence of intrahepatic type II perforation of the gall bladder in a previously healthy elderly male with acalculous cholecystitis. Lack of early positive findings related to clinical assessment, laboratory workup, and imaging resulted in a challenging diagnosis. High degree of clinical suspicion and close monitoring in such patients is necessary to detect early deterioration and improve outcomes.
Successful Treatment of Relapsed/Refractory Extramedullary Multiple Myeloma With Anti-BCMA CAR-T Cell Therapy Followed by Haploidentical Hematopoietic Stem Cell Transplantation: A Case Report and a Review of the Contemporary Literature
Authors: Ying Qian, Zijun Qian, Xiujie Zhao, Wenjue Pan, Xinzheng Wei, Huimin Meng, Lin Yang, Haowen Xiao
Journal: Front Med (Lausanne) (2021)
Keywords: chimeric antigen receptor t-cell, extramedullary multiple myeloma, haploidentical allogeneic hematopoietic stem cell transplantation, multiple myeloma, refractory
MeSH terms: Case Reports

Extramedullary multiple myeloma (EMM) is an aggressive sub-entity of multiple myeloma (MM). Despite an excellent improvement in survival for most patients with MM over recent decades, the overall survival (OS) of patients with EMM was usually not longer than 3 years. Standard treatment for patients with EMM has not been established, and their management is particularly challenging. We presented a heavily pretreated young patient with relapsed EMM and refractoriness to a proteasome inhibitor (PI; bortezomib), a next-generation PI (ixazomib), immunomodulatory drugs (IMiDs; lenalidomide), autologous hematopoietic stem cell transplantation (ASCT), and monoclonal antibody (directed against CD38: daratumumab) and indicated that myeloablative haploidentical hematopoietic stem cell transplantation (haploidentical-HSCT) as a salvage treatment of relapse after a chimeric antigen receptor (CAR)-T cell therapy that targeted B-cell maturation antigen (BCMA) (NCT04650724) is feasible. Taken together of the contemporary literature, the promising results on the effect of anti-BCMA CAR-T cell therapy and allogeneic HSCT might present a proof-of-principle for patients with EMM, and therefore, patients with the disease need to be included in future studies.
Incidental finding of a hidden central polydactyly: A case report
Authors: Mahir Bhoora, Dallan Dargan, Chris Milner
Journal: Clin Case Rep (2023)
Keywords: bifid distal phalanx, central polydactyly, congenital hand anomaly, hand trauma
MeSH terms: Case Reports

Congenital hand anomalies are common, and must always be considered as a differential diagnosis in patients with hand pathology. We report the case of a child who sustained a fingertip injury to highlight an unusual presentation of central polydactyly.
Severe Hypothyroidism due to the Loss of Therapeutic Efficacy of l-Thyroxine in a Patient with Esophageal Complication Associated with Systemic Sclerosis
Authors: Antonio Lobasso, Liliana Nappi, Letizia Barbieri, Carmela Peirce, Serena Ippolito, Debora Arpaia, Francesca Wanda Rossi, Amato de Paulis, Bernadette Biondi
Journal: Front Endocrinol (Lausanne) (2017)
Keywords: autoimmunity, hashomoto thyroiditis, hypothyrodism, l-thyroxine liquid formulation, sclerosis systemic, systemic sclerosis
MeSH terms: Case Reports

Background:
Thyroid function abnormalities and thyroid autoantibodies have been frequently described in patients with systemic autoimmune diseases as systemic sclerosis (SSc). Serum TSH levels are higher in SSc patients with more severe skin diseases and a worse modified Rodnan skin score. Asymptomatic esophageal involvement due to SSc has never been described as a cause of severe hypothyroidism due to l-thyroxine (l-T4) malabsorption in patients with Hashimoto's thyroiditis (HT) and SSc.
Case report:
Here, we report a case of a 56-year-old female affected by both SSc and HT who developed severe hypothyroidism due to the loss of therapeutic efficacy of l-T4. Therapeutic failure resulted from the altered l-T4 absorption because of SSc esophageal complications. Clinical findings improved after the administration of oral liquid l-T4. Thyroid function completely normalized with a full clinical recovery, the disappearance of the pericardial effusion and the improvement of the pulmonary pressure.
Conclusion:
A recognition of a poor absorption is crucial in patients with hypothyroidism and SSc to reduce the risk of the subsequent adverse events. This case suggests the importance of clinical and laboratory surveillance in patients with SSc and HT because the systemic complications of these dysfunctions may worsen the prognosis of hypothyroid SSc/HT patients.
Severe Anaphylactic Reaction to Diclofenac during Intravenous Anesthesia for In Vitro Fertilization
Authors: Nebojsa Videnovic, Nebojsa Markovic, Jovan Mladenovic, Marija Jovic, Rasa Mladenovic, Ranko Zdravkovic
Journal: Case Rep Emerg Med (2019)
MeSH terms: Case Reports

We present a case of a severe anaphylactic reaction to diclofenac, administered as an intravenous infusion in a 45-year-old patient, during intravenous anesthesia for in vitro fertilization. During the preoperative clinical examination and obtaining of anamnestic data, the patient denied symptoms of allergies to medicines and other substances. The dominant clinical manifestations of anaphylactic reaction were: hypotension, tachycardia, angioedema, bronchospasm, and delayed awakening following anesthesia. No visible changes in the appearance of the skin, such as erythema or urticaria have been observed. Proper clinical observation and adequate intraoperative monitoring led to rapid diagnosis and significantly reduced the time interval from the onset of anaphylaxis to the beginning of treatment and reanimation procedures.
Left anterior descending artery dissection with retrograde aortic dissection during percutaneous coronary intervention: a case report
Authors: Seha Ahn, Heejin Lee, Jung Suk Choi, Youngkyu Moon, In-Sub Kim, Si Young Choi, Joon Kyu Kang
Journal: Front Surg (2023)
Keywords: lad dissection, catheter-induced coronary artery dissection, off-pump coronary artery bypass graft, percutaneous coronary intervention, retrograde aortic dissection
MeSH terms: Case Reports

Retrograde catheter-induced coronary artery dissection during percutaneous coronary intervention is an exceedingly rare occurrence, and the likelihood of it extending into the aorta is even more uncommon. Typically, surgical treatment involves aortic root replacement combined with coronary artery bypass grafting. However, in this particular case, a meticulous approach was employed. By carefully guiding wires into the true lumens and placing stents in the proximal left main and left anterior descending arteries, the immediate complications were averted by obstructing the retrograde flow in the false lumen. Subsequently, an off-pump coronary artery bypass was performed using the left internal mammary artery to the left anterior descending artery, without the need to manipulate the aorta. This approach resulted in a short operation time and the absence of any other complications.