OpenMed/multicare-articles huggingface dataset:
Increased Anxiety, Akathisia, and Suicidal Thoughts in Patients with Mood Disorder on Aripiprazole and Lamotrigine
Authors: Milena Pereira Pondé, Antonio Carlos Cruz Freire
Journal: Case Rep Psychiatry (2015)

Introduction. Akathisia affects around 18% of patients with bipolar disorder treated with aripiprazole and may worsen when aripiprazole is combined with lamotrigine and antidepressants. Case. This paper reports on two clinical cases involving patients with a diagnosis of mood disorder who developed severe akathisia, anxiety, and suicidal ideation while using a combination of aripiprazole, antidepressants, and lamotrigine. Discussion. We recommend that patients with a mood disorder taking multiple drugs should begin aripiprazole therapy with low doses and be monitored for the development of akathisia, increased anxiety, or suicidal thoughts. The appearance of these limiting side effects requires discontinuation of the drug.
Extra hepatic biliary atresia associated with choledochal cyst: a diagnostic dilemma in neonatal obstructive jaundice
Authors: Shalini Sinha, Yogesh Kumar Sarin
Journal: J Neonatal Surg (2013)
Keywords: choledochal cyst, extra hepatic biliary atresia, neonatal obstructive jaundice
MeSH terms: Case Reports

The presentation of extra hepatic biliary-atresia (EHBA) as well as choledochal cyst (CDC) in the neonate may be similar. Since the surgical management and prognosis are entirely different, it is important to differentiate between the two entities. We present a case with co-existing EHBA and CDC which led to a diagnostic dilemma.
Anterior Palatal Fistula Formation after Le Fort I Osteotomy in Conventional Orthognathic Surgery
Authors: Saeed Nezafati, Tannaz Pourlak
Journal: Case Rep Dent (2023)
MeSH terms: Case Reports

The prevalence rate of maxillary ischemic complications following Le Fort I osteotomy was estimated to be about 1%. Understanding the local and systemic factors affecting maxillary perfusion before, during, and after the surgery can prevent the development of these complications. The present study investigated a case of anterior palatal fistula following the classic Le Fort I osteotomy.
Leflunomide-induced pulmonary arterial hypertension in a young man with nephrotic syndrome: A case report
Authors: Xiaoqin Luo, Jiang Li, Sisi Chen, Jun Luo
Journal: Front Pharmacol (2022)
Keywords: leflunomide, macitentan, nephrotic syndrome, pulmonary arterial hypertension, tadalafil
MeSH terms: Case Reports

Drug-induced pulmonary arterial hypertension (PAH) has been widely reported but PAH caused by leflunomide is very rare. Here we report the case of a young man with nephrotic syndrome treated with leflunomide for 5 years before being admitted to our hospital for dyspnea. After discontinuing leflunomide treatment for 4 months, both the dyspnea and pulmonary artery systolic pressure improved. Right heart catheterization showed in a significant decrease in pulmonary vascular resistance and pulmonary artery pressure 4 months later. Because persistent PAH can lead to right heart failure and even death, identifying and excluding the risk factors is critical; discontinuing leflunomide until a definite cause is identified is highly recommended.
Intramedullary schwannoma of the upper cervical spinal cord: a case study of identification in pathologic autopsy
Authors: Xianxian Li, Guangtao Xu, Ruibing Su, Junyao Lv, Xiaoping Lai, Xiaojun Yu
Journal: Forensic Sci Res (2017)
Keywords: forensic science, asphyxia, forensic pathology, intramedullary schwannoma, spinal cord
MeSH terms: Case Reports

Intramedullary schwannoma of the upper cervical spinal cord is rarely reported in forensic medicine. We herein report a case involving a patient who died of compression from an intramedullary schwannoma in the upper cervical spinal cord. A 30-year-old man initially presented with a five-day history of pain in the left chest that progressed to weakening in the left arm. Although the patient was treated with analgesic poultices, he developed inspiratory dyspnoea and died while working the next day without having undergone any medical imaging examination or surgical treatment. Anatomical and histopathological examinations revealed an intramedullary schwannoma in the left cervical spinal cord (C3-C5) underneath the spinal nerve root. The cause of death might have been asphyxia secondary to the tumour, which interfered with the nerve function in the respiratory muscles. This finding suggests that an autopsy is essential for pathologists and medicolegists to comprehensively undertake their due obligation to obtain "the first evidence", especially when there is a lack of directly related evidence. As part of the central nervous system, the spinal cord could be systematically included in a routine pathological autopsy in some cases.
Simultaneous presentation of giant aneurysms of the coronary sinus and superior vena cava
Authors: Yan Cheng, Huanhuan Gao, Zhelan Zheng, Yun Mou
Journal: Cardiovasc J Afr (2016)
MeSH terms: Aneurysm / etiology, Coronary Aneurysm / etiology, Heart Failure / complications, Vena Cava, Superior / diagnostic imaging, Vena Cava, Superior / physiopathology, Case Reports, Aneurysm / diagnostic imaging, Aneurysm / physiopathology, Aneurysm / therapy, Cardiovascular Agents / therapeutic use, Computed Tomography Angiography, Coronary Aneurysm / diagnostic imaging, Coronary Aneurysm / physiopathology, Coronary Aneurysm / therapy, Coronary Angiography / methods, Diastole, Dilatation, Pathologic, Disease Progression, Echocardiography, Doppler, Color, Echocardiography, Transesophageal, Female, Heart Failure / diagnostic imaging, Heart Failure / physiopathology, Heart Failure / therapy, Heart Transplantation, Humans, Multimodal Imaging / methods, Predictive Value of Tests, Risk Factors, Ventricular Function, Right, Waiting Lists, Young Adult, Cardiovascular Agents

Aneurysms of the coronary sinus and superior vena cava are rare and their aetiologies remain controversial. Some studies have shown that these acquired venous aneurysms are caused by an increase in right atrial pressure, which may be related to right heart failure. However, few reports have provided direct evidence to support this hypothesis. We present a rare case of combined giant aneurysms of the coronary sinus and vena cava, diagnosed using multiple imaging modalities. This case strongly supports the hypothesis that right heart diastolic failure may be an important mechanism underlying the pathogenesis of combined giant aneurysms.
Unusual complication of seroma after ventral hernia mesh repair: Digestive perforation by tacks. A case report
Authors: Mohamed Amine Elghali, Salsabil Nasri, Asma Seghaier, Khaireddine Dhouioui, Fehmi Hamila, Sabri Youssef, Rached Letaief
Journal: Int J Surg Case Rep (2018)
Keywords: digestive perforation, laparoscopy, mesh, seroma, tacker

Intraperitoneal meshes are actually widely used in ventral hernia repair. They can reduce operative time, parietal prejudice and postoperative pain. One of the most well-known complications of intraperitoneal mesh is seroma, but it usually subsides without any therapeutic problems. These meshes can be fixed by tackers, suture or glue. Few complications related to the fixation technique are known. We report the case of a patient who underwent a laparoscopic mesh repair for incisional hernia. He developed an infected bulky seroma for which he had to undergo medical treatment and percutanous drainage in order to avoid the mesh removal. The evolution seemed to be favorable until the occurrence of an unusual and unexpected complication: a digestive fistula of the small bowel in the seroma cavity via a tack adhering to the intestines. The possibility of digestive lesions by a tack is reported by some cases reports. It seems most often to be related to a technical problem. In our case, this adhesion seems to be secondary to the pressure exerted by the seroma. The complicated seroma can be conservatively treated to save the mesh. However the delay before deciding to remove the mesh when using tackers for its fixation may be shortened.
A Novel Variant of X-Linked Moesin Gene in a Boy With Inflammatory Bowel Disease Like Disease-A Case Report
Authors: Youhong Fang, Youyou Luo, Yang Liu, Jie Chen
Journal: Front Genet (2022)
Keywords: colitis, intestinal ulcer, moesin gene, primary immunodeficiency disease, very early-onset inflammatory bowel disease
MeSH terms: Case Reports

Variants in the MSN gene were recently reported as the cause of a primary immunodeficiency disease called X-linked moesin-associated immunodeficiency (X-MAID). Hitherto, only 10 patients were reported worldwide. Here, we report a boy who presented with recurrent high fever, oral ulcers, abdominal pain, and hematochezia for over 2 weeks. His serum inflammatory markers were elevated, and colonoscopy showed multiple colon ulcers and terminal ileum ulcers which resemble colitis caused by inflammatory bowel disease. A novel heterozygous variant c.934G>T(p.Glu312Ter) in the MSN gene was identified using whole exome sequencing (WES) and trio analysis. Intestinal ulcers were almost healed after inducing therapy with steroids and maintenance treatment of anti-TNFα therapy. We summarized the genotype and phenotype of reported X-MAID patients and presented the patient's unique phenotype in this study. This study also expanded the spectrum of MSN mutation-caused immunodeficiency.
Infantile fibrosarcoma in a child: a case report
Authors: A Hashemi, S Tefagh, A Seifadini, M Moghimi
Journal: Iran J Ped Hematol Oncol (2013)
Keywords: fibrosarcoma, infant, report
MeSH terms: Case Reports

Background:
Infantile Fibrosarcoma is a rare soft tissue tumor in infants and children mostly located in extremities. An infantile and adult form has similar histopathological patterns but survival prognosis is much better in infantile form. Recurrence of infantile fibrosarcoma is common but the rates of metastasis are less than 10 percent in children younger than five Years and 50 percent in children more than 10 years old.
Case presentation:
In this case report, we presented a nine years girl with a relapsing mass in her left hand. The pathologic findings showed sheets of spindle-shaped cells with suggested diagnose of infantile fibrosarcoma. She was successfully treated with combination of surgery and chemotherapy with a good outcome.
Conclusion:
Infantile fibrosarcoma is a differential diagnose of soft tissue mass in infants and children. It has a good prognosis and distant metastasis is uncommon. Choice of treatment is surgery but chemotherapy and radiotherapy were useful in decrease metastasis.
Case Report: J-Shaped External Fixator for Treatment of Mayo Type II Olecranon Fractures - A Novel Surgical Technique and Report of Clinical Applications
Authors: Yue Tian, Xin Ge, Jiyang Zou, Fenglei Song, John Chun Tien Chui Wan Cheong, Changqing Ge, Weiguo Zhang, Jie Li, Kang Tian
Journal: Front Surg (2022)
Keywords: case series, elbow, external fixation, fracture, olecranon fractures
MeSH terms: Case Reports

Purpose:
We designed a J-shaped external fixator (J-EF) to provide a minimally invasive, one-step surgical method for olecranon fractures. The aim of this study is to retrospectively review the method and the outcomes in 14 patients treated with J-EF fixation.
Methods:
Biomechanical comparative study was performed to test the tensile properties of the J-EF using a universal testing machine. Between January 2002 and December 2005, 14 patients (age range: 25-67 years) with Mayo type II olecranon fractures were treated using the external fixation technique. Follow-up was done by standard measures (radiography, range of motion, and complications monitoring) and patient-reported outcomes (Mayo Elbow Performance Score [MEPS] and Disabilities of the Arm, Shoulder, and Hand [DASH] scores) 6 months after surgery. Eight of the patients were reviewed 15 years after the surgery.
Results:
Results from biomechanical studies indicate the non-inferiority of J-EF to tension-band wiring (TBW) in tensile properties. At the time of release, the mean elbow flexion arc was 132.5° and the mean forearm rotation arc was 173.6°. The mean DASH score was 14.1 points, and the mean MEPS was 93.9 points. Operative time and intraoperative blood loss were decreased by 41.3% and 64.6%, respectively, in J-EF patients than those in a comparable group treated by TBW. All eight patients are still alive after the surgery and maintaining the original outcome.
Conclusions:
External fixation using the J-EF could be considered as an alternative treatment for Mayo type II olecranon fractures as it appears to be a reliable, minimally invasive, and time-saving.
Level of evidence:
Therapeutic Level IV.
Symptomatic IgG4-Related Prostatitis Simultaneously Diagnosed with Aggressive Prostate Cancer
Authors: Taisuke Ezaki, Seiya Akatsuka, Tansei Sanjo, Takeshi Masuda
Journal: Case Rep Urol (2020)
MeSH terms: Case Reports

IgG4-related disease is a systemic fibroinflammatory disorder that occasionally affects the prostate. It is usually considered that patients with IgG4-related disease are at high risk of developing malignancies. A 71-year-old man presented to our hospital with a chief complaint of urinary retention. Prostate biopsy revealed concomitant IgG4-related prostatitis and prostate cancer. IgG4-related prostatitis was a possible cause of urinary retention, and the aggressive nature of prostate cancer was the cause of the patient's death 2 years after diagnosis. This is the fourth case report of prostate cancer accompanied by IgG4-related prostatitis; however, there have been no reports of the two diseases coexisting with high clinical significance. Our case report indicates that patients diagnosed with IgG4-related prostatitis should be carefully followed up considering the risk of prostate cancer.
Laparoscopic sleeve gastrectomy in polysplenia syndrome/left isomerism: A case report
Authors: Fatemah Jeragh, Ismaiel Aljazzaf, Haitham Al Khayyat
Journal: Int J Surg Case Rep (2020)
Keywords: bariatric surgery, laparoscopic sleeve gastrectomy, left isomerism, morbid obesity, polysplenia syndrome
MeSH terms: Case Reports

Introduction:
This is a case report that presents an unusual case of Polysplenia Syndrome (PSP) undergoing laparoscopic sleeve gastrectomy (LSG). This kind of presentation would be of interest to general surgeons who perform bariatric surgery.
Presentation of case:
The case presented is a 28-year-old female patient who was not a known case of Polysplenia Syndrome. During the patients' pre-operative assessment, physical examination was done and a type of heterotaxy syndrome was suspected upon palpation of the stomach. Therefore, Computed Tomography (CT) imaging was performed which confirmed PSP. She underwent laparoscopic sleeve gastrectomy due to her morbid obesity, as her Body Mass Index (BMI) was 40.8 kg/m2. Post-operatively, water soluble contrast study was performed to rule out leak and the patient had uneventful follow-up.
Discussion and conclusion:
The surgical approach of such patients is somewhat similar to those with situs solitus; however, the performing surgeon must take into consideration the anatomical orientation. Proper assessment of such patients prior to surgery with history, full physical examination, and fitting imaging modalities is essential.
Frontotemporal dementia and neurocysticercosis: A case report
Authors: Corina Satler, Elza Santos Maestro, Carlos Tomaz
Journal: Dement Neuropsychol (2012)
Keywords: frontotemporal lobar degeneration, neurocysticercosis, neuropsychological assessment, progressive nonfluent aphasia
MeSH terms: Case Reports

We report a case of a 67-year-old woman with frontotemporal dementia (FTD) and a history of neurocysticercosis. After her retirement she showed progressive behavioral changes and neuropsychiatric symptoms with relative preservation of cognitive functioning. During the next three years, the patient manifested progressive deterioration of verbal communication gradually evolving to mutism, a hallmark of cases of progressive nonfluent aphasia.
Imaging and clinical findings in a case of linear scleroderma en coup de sabre
Authors: Conal M Corbally, Andrew Breckenridge, Ravi Jampana
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

We present the case of a 58-year-old female presenting with acute onset headache and decrease in left-sided facial sensation. The patient's background included diabetes Type 2, hypertension, migraine, anxiety with depression and scleroderma in her childhood. Imaging revealed foci of right frontal calcification and confluent white matter changes, reported as sequelae of a previous ischaemic episode. Following a second presentation with the same symptoms, further imaging showed a linear soft tissue scar overlying these changes, which suggested a diagnosis of linear scleroderma (en coup de sabre). On questioning, it was found that this had developed during the patient's late teens but had not progressed since that time. Coup de sabre type linear scleroderma is often associated with intracranial imaging findings, even in the absence of symptoms. The pathogenesis of neurological symptoms is poorly understood but does seem to respond to immunosuppression.
Case Report of Atlantoaxial Rotatory Fixation after Cochlear Implantation
Authors: Takahiro Nakashima, Keiji Matsuda, Takumi Okuda, Tetsuya Tono, Minoru Takaki, Tamon Hayashi, Yutaka Hanamure
Journal: Case Rep Otolaryngol (2016)

Atlantoaxial rotatory fixation (AARF) is a relatively rare condition and is mainly seen in children. We report of a 7-year-old girl suffering from AARF after cochlear implantation (CI). Fortunately, early diagnosis based on three-dimensional computed tomography (3DCT) was made, and the patient was cured with conservative therapy. Nontraumatic AARF, which is also known as Grisel's syndrome and occurs subsequent to neck infections or ear, nose, and throat (ENT) surgery, represents only a small fraction of AARF cases. Two factors are mainly thought to contribute to the pathogenesis of the condition estimated, namely, (i) neck immaturity in children and (ii) infiltration by inflammatory mediators around the upper neck joint, easily permitted by the neck vasculature. AARF should be suspected in case of torticollis developing after ENT surgery.
Infective Spondylitis with Epidural Abscess Formation Caused by Roseomonas mucosa: A Case Report and Literature Review
Authors: Zong-Han Lin, Yu-Chang Lu, Kuan-Sheng Wu
Journal: Case Rep Infect Dis (2023)
MeSH terms: Case Reports

Roseomonas mucosa (R. mucosa) is a pink-pigmented, aerobic, nonfermentative, slow-growing Gram-negative coccus typically isolated from the natural environment, human skin, and hospital environment. This pathogen, in most circumstances, leads to infections in immunocompromised hosts, but it may sometimes invade immunocompetent individuals. Bacteraemia is the most common form of infection caused by R. mucosa. In contrast, only two case reports have described R. mucosa-related epidural abscess formation and infective spondylitis. In this case report, we shared the history and treatment experience of a 76-year-old female who was diagnosed with infective spondylitis and epidural abscess caused by R. mucosa. She received a local transdermal injection into the lower back to relieve her back pain two months before symptom onset, which was considered to be associated with this infection episode. After admission to the hospital, neurosurgeons performed emergent decompression and debridement. She was treated with intravenous ceftriaxone for four weeks, followed by oral ciprofloxacin for another eight weeks. The patient recovered well without any sequelae and had no relapse of infection at least six months after the end of treatment. In addition to the case report, we reviewed the literature for reported cases caused by R. mucosa. Our experience suggests that clinicians should include R. mucosa as one of the possible healthcare-associated pathogens among individuals who have undergone transdermal procedures. We believe that this article will help clinicians better recognize R. mucosa infection.
Progress, but at the Expense of Male Power? Institutional Resistance to Gender Equality in an Irish University
Authors: M Hodgins, P O'Connor
Journal: Front Sociol (2021)
Keywords: associate professor, gender equality, institutional resistance, internal promotion, male power, university, irish

Gender equality is a whole-organization endeavor. Building on Agócs (Journal of Business Ethics, 1997, 16 (9), 917-931) concept of institutionalized resistance this article undertakes a feminist critique of policy and practice around internal promotions to the equivalent of Associate Professor level in one Irish university (called the Case Study University). This university was selected because of its low proportion of women in senior academic positions. The methodology is a single case study design, employing documentary analysis, including secondary data. Since 2013 the proportion of women at Associate Professor in the Case Study University increased significantly (bringing them close to the national average): this being associated with increased transparency, with the cascade model in the background. However, men's "chances" have varied little over time and at 1:4 are the highest in Irish universities. This article uses Agócs (Journal of Business Ethics, 1997, 16 (9), 917-931) stages of institutional resistance to show that while some changes have been made, ongoing institutionalized resistance is reflected in its failure to accept responsibility for change as reflected in its refusal to challenge the "core mission" and restricting the focus to "fixing the women"; and its failure to implement change by focusing on "busy-ness" which does not challenge power and colluding with foot-dragging and slippage in key areas. It is suggested that such institutional resistance reflects the enactment of hidden or stealth power. The article implicitly raises questions about the intractability and the covertness of men's power and privilege and the conditions under which women's "chances" are allowed to improve, thus providing insights into the extent and nature of institutional resistance.
Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature
Authors: Deepti Kantamani, Sai S Bandaru, Jennifer L Miatech, M Patrick Stagg
Journal: Case Rep Oncol Med (2021)
MeSH terms: Case Reports

Salivary duct carcinoma (SDC) is an uncommon and highly aggressive tumor associated with high morbidity and mortality. According to the World Health Organization, it is an extremely rare malignancy with an estimated incidence of 1-1.2 in 1,000,000 patients. Standard treatment for SDC is wide surgical resection along with lymph node dissection followed by adjuvant radiation therapy. The role of adjuvant chemotherapy is not known. In this report, we present three cases of SDC. A 71-year-old female with T1N0M0 disease was treated with total parotidectomy, ipsilateral neck dissection, and adjuvant radiotherapy without evidence of disease recurrence at 5 months. The second is a 59-year-old female with TXN1M0 disease who was treated with total parotidectomy with ipsilateral level I-IV neck dissection and adjuvant radiotherapy without evidence of disease occurrence at 21 months. The third case is a 79-year-old male with widely metastatic disease, including brain metastases, treated with cranial irradiation, leuprolide, and lapatinib who remains under home hospice care.