OpenMed/multicare-articles huggingface dataset:
A Rare Presentation of Coinfection: Dengue Virus and Hepatitis A Virus
Authors: I Ranathunga, L S Kannangara, K A S Bandara, S B Gunatilake
Journal: Case Rep Infect Dis (2019)
MeSH terms: Case Reports

Dengue fever caused by dengue virus is a common tropical infection transmitted by the mosquitos Aedes aegypti and Aedes albopictus. Four strains of the genus flavivirus is responsible for the epidemics of varying severity. Hepatitis A caused by hepatitis A virus is spread by faecal-oral route. The culprit virus is a hepatovirus. Coinfection with dengue virus and hepatitis A virus is rare and is a diagnostic as well as management challenge to the medical professional. We report a patient who presented to us with dengue virus and hepatitis A virus coinfection.
Management of primary cardiac leiomyosarcoma
Authors: Lucrecia Aline Cabral Formigosa, Luciana Ferreira Dos Santos, Jaqueline Dantas Neres Martins, Bianca Silva de Brito, Hemilly Vasconcelos de Miranda Silva, Ricardo Luiz Saldanha da Silva, Josinete da Conceição Barros do Carmo, Samara Machado Castilho
Journal: Ecancermedicalscience (2023)
Keywords: case report, heart atria, heart neoplasms, leiomyosarcoma
MeSH terms: Case Reports

Background:
Primary cardiac cancer is a rare event with various clinical presentations and often causes unexpected symptoms or sudden death. Case reports with this diagnosis are scarce.
Case presentation:
We present an unusual manifestation of leiomyosarcoma of the left atrium in a female patient, 33 years old. Presenting difficulty to walk, dyspnoea at rest, skin pallor, cough with hemoptoics and syncope. A transthoracic echocardiogram showed cavitary enlargement of the left atrium, moderate to significant mitral stenosis with an adherent mass in the anterior leaflet, left ventricular systolic function preserved at rest, and mild aortic and tricuspid insufficiency. The procedure was complete resection of the tumour or negative microscopic margins (R0 resection), 25 sessions of radiotherapy, 5 cycles of adjuvant chemotherapy using gemcitabine (900 mg/m2 on days 1 and 8) and docetaxel (75 mg/m2 on day 8), with a resolution of the clinical picture. After 5 years of follow-up, the patient had no metastases or recurrence of the initial tumour.
Conclusion:
The nonspecific symptoms presented in the reported case demonstrate that the cardiac tumour can mimic other cardiac disorders, such as coronary artery disease or pericarditis, rarely representing the first manifestation of a previously unknown malignancy.
Fetal Valproate Syndrome with Limb Defects: An Indian Case Report
Authors: Manisha Goyal, Ashok Gupta, Manish Sharma, Priyanshu Mathur, Naresh Bansal
Journal: Case Rep Pediatr (2016)

Epilepsy is a common disorder and exposure to antiepileptic drugs during pregnancy increases the risk of teratogenicity. Older AEDs such as valproate and phenobarbital are associated with a higher risk of major malformations in the fetus than newer AEDs like lamotrigine and levetiracetam. Exposure to valproic acid during first trimester can result in fetal valproate syndrome (FVS), comprising typical facial features, developmental delay, and a variety of malformations such as neural tube defects, cardiac and genitourinary malformations, and limb defects. We are presenting an Indian case of FVS with major limb defects.
"Crack, Reduce, and Implant": A Safe Phaco Technique in a Case with Hard Brown Cataract
Authors: Ibrahim Toprak, Volkan Yaylali
Journal: Case Rep Med (2019)
MeSH terms: Case Reports

This report describes two maneuvers in different steps of phaco surgery in a case with hard cataract, which provide debulking of the central dense nucleus and prevents posterior capsule rupture (PCR). In the current case, clear corneal incisions were created, and anterior chamber was filled with ophthalmic viscosurgical device (OVD). Anterior capsule was punctured, and capsulorhexis was completed. Nucleus was cracked into two halves following vertical groove formation. Core nucleus was hollowed sideward bilaterally in the capsular bag. Nuclear halves were removed from capsular bag, and each one was pushed to one side on the iris plane. Capsular bag was inflated with OVD, and intraocular lens (IOL) was implanted. Nuclear halves were removed in confidence. The presented maneuvers initially reduce dense nucleus load in the safe zone and allow surgeon to use IOL as a barrier to protect floppy posterior capsule from early steps of the surgery.
Ectopic adrenal gland tissue in the left ovary of an elderly woman: a case report
Authors: Seon Mi Lee, Jong Chul Baek, Ji Eun Park, Hyen Chul Jo, Hyun Min Koh
Journal: Pan Afr Med J (2021)
Keywords: ectopic adrenal gland, case report, elderly woman, pelvic ovary
MeSH terms: Leiomyoma, Ovary, Case Reports, Adrenal Glands, Aged, Female, Humans, Hysterectomy, Salpingo-oophorectomy

Ectopic adrenal gland in the ovary is very rare case, and even more rarer in older women. We reported a case of ectopic adrenal tissue as an incidental finding in left ovary from a 68-year-old woman. She presented with bearing down sensation due to uterine prolapse for 5 years. Upon physical examination, uterine prolapse grade III, cystocele, and rectocele were observed. Ultrasonography findings showed 0.69 cm intramural myoma, and no specific findings were found in the bilateral adnexae. She underwent a total laparoscopic hysterectomy, bilateral salpingo-oophorectomy, and anterior-posterior repair. The final pathologic diagnosis of the case was ectopic adrenal gland tissue in the left ovary and uterine leiomyoma. No eventful reactions were observed during hospitalization and after discharge. Although ectopic adrenal gland rarely occurs in elderly women and in the pelvic ovaries, it has a risk of neoplastic transformation and accompanying germ cell tumor and sex cord tumor. Hence, if the ectopic adrenal gland tissue is suspected during surgery, the tissue should be removed. Additionally, by closely examining the contralateral ovary, determining whether other lesions are suspected is necessary. If the other lesions including germ cell tumor or sex cord tumor are suspected, a biopsy of the contralateral ovarian tissue should be performed. Thus, gynecologists must have knowledge about ectopic adrenal gland tissues.
Natural Infection by SARS-CoV-2 in Companion Animals: A Review of Case Reports and Current Evidence of Their Role in the Epidemiology of COVID-19
Authors: Helio Autran de Morais, Andrea Pires Dos Santos, Naila Cannes do Nascimento, Louise Bach Kmetiuk, David Soeiro Barbosa, Paulo Eduardo Brandão, Ana Marcia Sá Guimarães, Christina Pettan-Brewer, Alexander Welker Biondo
Journal: Front Vet Sci (2020)
Keywords: cats, coronavirus, dogs, pets, transmission
MeSH terms: Review

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), is the causative infectious agent of the current pandemic. As researchers and health professionals are still learning the capabilities of this virus, public health concerns arise regarding the zoonotic potential of SARS-CoV-2. With millions of people detected with SARS-CoV-2 worldwide, reports of companion animals possibly infected with the virus started to emerge. Therefore, our aim is to review reported cases of animals naturally infected with SARS-CoV-2, particularly companion pets, shedding light on the role of these animals in the epidemiology of COVID-19.
Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain
Authors: Jason R Andrews, Yoon Andrew Cho-Park, Judith Ferry, Jeremy S Abramson, Gregory K Robbins
Journal: AIDS Res Treat (2011)
MeSH terms: Case Reports

Since its discovery in 1994, Kaposi's sarcoma-associated herpesvirus (KSHV) has been associated with lymphoproliferative disorders, particularly in patients infected with human immunodeficiency virus (HIV). The disorders most strongly linked to KSHV are multicentric Castleman's Disease (MCD), primary effusion lymphoma, and diffuse large B-cell lymphomas. We report an unusual case of KSHV-associated lymphoma in an HIV-infected patient manifesting with myocardial and central nervous system involvement. We discuss this case in the context of increasing array of KSHV-associated lymphomas. In the HIV-infected patient with a mass lesion, a history of cutaneous Kaposi's sarcoma and prolonged immunosuppression should alert clinicians as to the possibility of KSHV-associated lymphoproliferative disorders, in order to establish a timely diagnosis.
Familial Essential Thrombocythemia Associated with MPL W515L Mutation in Father and JAK2 V617F Mutation in Daughter
Authors: Adrian P Trifa, Andrei Cucuianu, Radu A Popp
Journal: Case Rep Hematol (2014)

Familial essential thrombocythemia features the acquisition of somatic mutations and an evolution similar to the sporadic form of the disease. Here we report two patients-father and daughter-with essential thrombocythemia who displayed a heterogeneous pattern of somatic mutations. The JAK2 V617F mutation was found in the daughter, while the father harbored the MPL W515L mutation. This case report may constitute further proof that in familial essential thrombocythemia there are other, still undefined, constitutional, inherited genetic factors predisposing to the acquisition of various somatic mutations (e.g., JAK2 V617F and MPL).
Communicating Bronchopulmonary Foregut Malformation Type IB: Diagnostic and Surgical Challenges
Authors: Bhushanrao Jadhav, Ranjithatharsini Vaseeharan, Prabhu Sekaran, Semiu Eniola Folaranmi, Karim Awad
Journal: European J Pediatr Surg Rep (2021)
Keywords: communicating bronchopulmonary foregut malformations, esophageal atresia and tracheoesophageal fistula, esophageal lung
MeSH terms: Case Reports

Communicating bronchopulmonary foregut malformations (CBPFM) are extremely rare. We present a complex case of type IB CBPFM with esophageal atresia and distal tracheoesophageal fistula (EA/TOF), duodenal atresia/annular pancreas (DA/AP), and intestinal malrotation who underwent primary repair for EA/TOF on day 3. Bilious aspirates on day 8 prompted an upper gastrointestinal (GI) contrast revealing a duodenal obstruction and communication between the right lung lower lobe and the esophagus (T8-T9 level). DA/AP and malrotation were repaired by a gastrojejunostomy and Ladd's procedure. A repeat contrast swallow identified a 2nd communication from the esophagus into the right lower lobe (T5-T6 level) raising the suspicion of a recurrent TOF. Computed tomography (CT) thorax confirmed above findings with an anomalous blood supply to right lung. An exploratory thoracotomy identified a three-lobed lung. However, the lower lobe was enlarged and connected in two separate locations to the esophagus. The child recovered after the disconnection of the esophageal connections and partial right lower lobectomy. CBPFM are extremely rare anomalies requiring a high index of suspicion, use of an upper GI contrast series, and CT scans for diagnosis. The treatment of choice is resection of the affected lung and disconnection of the esophageal communications.
A favorable outcome of dengue hemorrhagic fever despite poor prognostic indices: a case report with a mix of classic and unusual clinical and laboratory features
Authors: Olukemi Adekanmbi, Sulaiman Lakoh
Journal: Pan Afr Med J (2019)
Keywords: dengue, fever, viral hemorrhagic fever
MeSH terms: Intensive Care Units, Severe Dengue / therapy, Case Reports, Adult, Humans, Male, Prognosis, Severe Dengue / physiopathology, Treatment Outcome

The report describes a 32-year-old man with dengue hemorrhagic fever presenting with acute onset high-grade intermittent fever with chills and rigors, headache, myalgia, abdominal pain, and vomiting. His laboratory results revealed neutrophilia, thrombocytopenia, microscopic hematuria, and a markedly elevated D-dimer. While on admission, he developed diarrhea, hypertension, and respiratory symptoms which evolved into respiratory distress with low oxygen saturation, eventually warranting his admission to the Intensive Care Unit (ICU). Despite his adverse prognostic indices, the patient made an uneventful recovery with conservative management after 16 days of admission. Thus illustrating how aggressive management could influence the outcome of dengue illness.
Buddhism, Christianity, and psychotherapy: A three-way conversation in the mid-twentieth century
Authors: Christopher Harding
Journal: Eur J Psychother Couns (2018)
Keywords: carl rogers, kosawa heisaku, kosawa heisaku, paul illich, paul tillich, dialogo religione-psi, dialogue religion-psy, disciplinas psicológicas, discipline psicologiche, disciplines psy, diálogo entre la psicoterapia y la religión, psy disciplines, religion-psy dialogue, διάλογος ανάμεσα στη θρησκεία και στην ψυχολογία, σχολές

This article explores the scope of 'religion-psy dialogue' in the mid-twentieth century, via a case study from Japan: Kosawa Heisaku, a Buddhist psychoanalyst based in Tokyo. By putting this case study in brief comparative perspective, with the conversation that took place in 1965 between Paul Tillich and Carl Rogers, the article discusses both the promise and the pitfalls of the modern and contemporary world of 'religion-psy dialogue', alongside the means by which specialists in a variety of fields might investigate and hold it to account.
Oculodentodigital Dysplasia: A Case Report and Major Review of the Eye and Ocular Adnexa Features of 295 Reported Cases
Authors: Virang Kumar, Natario L Couser, Arti Pandya
Journal: Case Rep Ophthalmol Med (2020)
MeSH terms: Case Reports

Oculodentodigital dysplasia (ODDD) is a rare genetic disorder associated with a characteristic craniofacial profile with variable dental, limb, eye, and ocular adnexa abnormalities. We performed an extensive literature review to highlight key eye features in patients with ODDD and report a new case of a female patient with a heterozygous missense GJA1 mutation (c.65G>A, p.G22E) and clinical features consistent with the condition. Our patient presented with multiple congenital anomalies including syndactyly, microphthalmia, microcornea, retrognathia, and a small nose with hypoplastic alae and prominent columella; in addition, an omphalocele defect was present, which has not been reported in previous cases. A systematic review of the published cases to date revealed 91 literature reports of 295 individuals with ODDD. There were 73 different GJA1 mutations associated with these cases, of which the most common were the following missense mutations: c.605G>A (p.R202H) (11%), c.389T>C (p.I130T) (10%), and c.119C>T (p.A40V) (10%). Mutations most commonly affect the extracellular-1 and cytoplasmic-1 domains of connexin-43 (gene product of GJA1), predominately manifesting in microphthalmia and microcornea. The syndrome appears with an approximately equal sex ratio. The most common eye features reported among all mutations were microcornea, microphthalmia, short palpebral fissures, and glaucoma.
Intraoperative rupture of popliteal artery pseudoaneurysm secondary to distal femur osteochondroma: case report and review of the literature
Authors: Rita Hajji, Hamid Jiber, Youssef Zrihni, Othman Zizi, Abdellatif Bouarroum
Journal: Pan Afr Med J (2013)
Keywords: exostoses, osteochondroma, popliteal artery pseudoaneurysme
MeSH terms: Aneurysm, False / etiology, Aneurysm, Ruptured / etiology, Bone Neoplasms / complications, Osteochondroma / complications, Case Reports, Review, Aneurysm, False / pathology, Bone Neoplasms / surgery, Femur, Humans, Intraoperative Complications, Male, Osteochondroma / surgery, Popliteal Artery, Young Adult

Vascular complications from osteochondroma are rare and include essentially stenosis, occlusion, and pseudoaneurysms. The authors report an original case of intraoperative rupture of undiagnosed popliteal artery pseudoaneurysm during resection surgery for a distal femur osteochondroma.
Ruptured hepatic metastases of cutaneous melanoma during treatment with vemurafenib: an autopsy case report
Authors: Takuto Nosaka, Katsushi Hiramatsu, Tomoyuki Nemoto, Yasushi Saito, Yoshihiko Ozaki, Kazuto Takahashi, Tatsushi Naito, Kazuya Ofuji, Hidetaka Matsuda, Masahiro Ohtani, Hiroyuki Suto, Yoshiaki Imamura, Yasunari Nakamoto
Journal: BMC Clin Pathol (2015)
MeSH terms: Case Reports

Background:
The spontaneous rupture of hepatic metastases is rare compared to that of primary hepatic tumors. In addition, vemurafenib, a selective inhibitor of the mutant BRAF protein or gene product, has been reported to be extremely effective in patients with metastatic melanoma who harbor a BRAF V600E mutation.
Case presentation:
A 44-year-old female had previously undergone surgery for resection of a malignant melanoma in the lower right leg. Four years later, hepatic metastases became apparent, and transcatheter arterial embolization (TAE) was performed. Then she underwent treatment with vemurafenib. The size of the hepatic metastases markedly decreased. Two months later, they enlarged rapidly and ruptured, requiring emergency TAE. However, the patient developed hemorrhagic shock and died of renewed intra-abdominal bleeding on the 26th postoperative day.
Conclusions:
This is a rare case of ruptured hepatic metastases of malignant melanoma during treatment with vemurafenib. Postmortem examination and immunohistochemical analysis indicated reactivation of the mitogen-activated protein kinase pathway in the metastatic tumor, suggesting secondary resistance to vemurafenib as the possible underlying mechanism.
Acrofacial necrotic ulcers in an infant: An undiagnosed presentation
Authors: Georgina-Maria Sarika, Rony Shreberk-Hassidim, Alexander Maly, Vered Molho-Pessach
Journal: Front Pediatr (2022)
Keywords: acrofacial necrotic ulcers, lipodystrophy, perniosis, type 1 interferonopathies, undiagnosed cases
MeSH terms: Case Reports

Acral necrotic ulcers in infancy are rare but have been described in type I interferonopathies. Herein, we present a case of an 8-year-old child who presented at the age of one month with severe ulceronecrotic lesions on the face and limbs with exacerbations following exposure to cold weather. Despite extensive investigation the case remains undiagnosed to this day. We hypothesize that this case represents a novel and yet unknown autoinflammatory disease.
Reconstruction of the Peroneus Brevis Tendon Tears with Semitendinosus Tendon Autograft
Authors: Danilo Ryuko Cândido Nishikawa, Fernando Aires Duarte, Guilherme Honda Saito, Cesar de Cesar Netto, Augusto César Monteiro, Marcelo Pires Prado, Ivan Furlan Grava de Sousa
Journal: Case Rep Orthop (2019)
MeSH terms: Case Reports

Peroneal tendon disorders are common causes of lateral and retromalleolar ankle pain. For irreparable tears of the tendon, a salvage procedure is indicated with segmental resection followed by reconstruction with tenodesis, tendon transfer, or bridging the defect using allograft or autograft. Although there is insufficient evidence to guide which of these treatment options provides the best outcomes, reconstruction with tendon allograft has provided satisfactory clinical results and is effective for pain relief and restoration of tendon function. However, there are concerns about the use of tendon allografts which include its cost and availability, disease transmission, delayed incorporation, and stretching of the graft. The aim of this study is to present the surgical technique for the reconstruction of the peroneus brevis tendon tears using semitendinosus tendon autograft as an alternative to the allograft and report the short-term results of three cases.
Leiomyosarcoma of the portal vein: a case report and review of the literature
Authors: Wan Hang Keith Chiu, Anthony Wi Lo, Joseph Kt Lee
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

Leiomyosarcomas (LMS) are rare malignant tumours of smooth muscle origin predominately affecting females in their sixth decade. Only 2% of LMS arise from blood vessels and most are in the inferior vena cava. We present the first reported case of LMS of the portal vein in a male patient. Multidetector CT showed a large mass in the main portal vein, which was initially misinterpreted as a pancreatic cancer. Careful examination of the multidetector CT images showed radiological features of an intraluminal mass, and a preoperative diagnosis of primary LMS of the main portal vein was made. The patient underwent curative surgery and made an uneventful recovery. Awareness of this entity and recognition of the salient CT features may facilitate radiologists in making the correct preoperative diagnosis.
Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection
Authors: Shi-Mei Huang, Yu-Rong Tang, Ji-Liang Wang, Xiao-Zhen Wang, Yuan-Yuan Zhang, Su-Fei Pan
Journal: Front Cell Infect Microbiol (2023)
Keywords: mycoplasma hominis, pseudomonas aeruginosa, case report, infection, infectious diseases
MeSH terms: Anti-Infective Agents, Coinfection / drug therapy, Mycoplasma Infections / diagnosis, Mycoplasma Infections / drug therapy, Pseudomonas Infections / diagnosis, Pseudomonas Infections / drug therapy, Case Reports, Adult, Anti-Bacterial Agents / therapeutic use, Humans, Male, Mycoplasma hominis / genetics, Pseudomonas aeruginosa / genetics, RNA, Ribosomal, 16S, RNA, Ribosomal, 16S, Anti-Infective Agents, Anti-Bacterial Agents

Background:
Extra-urogenital infections due to Mycoplasma hominis (M. hominis) are rare, particularly co-infection with Pseudomonas aeruginosa (P. aeruginosa). Herein, we report on a patient who was co-infected and successfully treated despite delayed treatment.
Case presentation:
We reported the case of a 43-year-old man with M. hominis and P. aeruginosa co-infection after a traffic accident. The patient developed a fever and severe infection despite postoperative antimicrobial therapies. The blood culture of wound tissues was positive for P. aeruginosa. Meanwhile, culturing of blood and wound samples showed pinpoint-sized colonies on blood agar plates and fried-egg-type colonies on mycoplasma medium, which were identified as M. hominis by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA sequencing. Based on antibiotic susceptibility and symptoms, ceftazidime-avibactam and moxifloxacin were administered for P. aeruginosa infection. Meanwhile, after the failure of a series of anti-infective agents, M. hominis and P. aeruginosa co-infection was successfully treated with a minocycline-based regimen and polymyxin B.
Conclusion:
The co-infection with M. hominis and P. aeruginosa was successfully treated with anti-infective agents despite delayed treatment, providing information for the management of double infection.