OpenMed/multicare-articles huggingface dataset:
Accidental cutaneous burns secondary to salbutamol metered dose inhaler
Authors: Ashutosh Kale, Fiona Shackley
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

We report a case of accidental cutaneous burns caused by salbutamol metered dose inhaler. A 9-year-old boy underwent dental extraction at a children's hospital and was incidentally noted to have burn injuries on dorsum of both hands. On questioning, the boy revealed that a few days ago his 14-year-old brother, who is an asthmatic, playfully sprayed his salbutamol metered dose inhaler on the back of both his hands with the inhaler's mouth piece being in direct contact with the patient's skin. On examination, there was a rectangular area of erythema with superficial peeling on the dorsum of both hands, the dimensions of which exactly matched those of the inhaler's mouthpiece. It is possible that the injury could have been a chemical burn from the pharmaceutical/preservative/propellant aerosol or due to the physical effect of severe cooling of the skin or mechanical abrasive effect of the aerosol blasts or a combination of some or all the above mechanisms. This case highlights the importance of informing children and parents of the potentially hazardous consequences of misusing a metered dose inhaler.
Unmasking dermatofibrosarcoma protuberans: Case report of an atypical presentation complicated by post-surgical excision
Authors: YaQun Zhou Arlene, Justin Chin, Millard D Strutin, Christine M Lomiguen
Journal: Int J Surg Case Rep (2020)
Keywords: cd34, case report, dfsp, dermatofibrosarcoma protuberans, lipoma, soft tissue tumor
MeSH terms: Case Reports

Introduction:
Dermatofibrosarcoma Protuberans (DFSP) is a rare type of malignant tumor of the cutaneous soft tissue that typically involves the dermis and surrounding structures. The typical clinical presentation involves an asymptomatic, slowly enlarging, indurated plaque, usually found on the trunk.
Presentation of case:
Here we present an atypical presentation of DFSP in a patient with a recurrent mass that was initially diagnosed as a lipoma, with supporting literature and clinical considerations for post-surgical management DISCUSSION: In its earlier stages, DFSP can mimic other benign or malignant dermatological pathologies, which can complicate diagnosis purely via history and physical exam. Atypical features such as prior surgical management, morphology, and location can complicate the clinical diagnosis of DFSP. Immunohistochemistry is often required for definitive diagnosis as DFSP is CD34+ and is histologically described as spindle-cells in whorled or storiform pattern, with uniform, small elongated cells.
Conclusion:
DFSP is a rare tumor of the skin and subcutaneous tissue. Though it commonly presents with induration, skin discoloration, and telangiectasias, it is important to keep DFSP as a differential in new masses found on previous surgical sites, especially if the previous mass had a possibility of recurrence.
Pure red cell aplasia after 13 years of sodium valproate, and bone marrow suppression after 17 years of carbamazepine
Authors: Tiong The, Ratnavalli Kolla, Fitzroy Dawkins, Annapurni Jayam Trouth
Journal: PLoS Med (2004)
MeSH terms: Anticonvulsants / adverse effects, Carbamazepine / adverse effects, Red-Cell Aplasia, Pure / chemically induced, Valproic Acid / adverse effects, Case Reports, Adult, Anticonvulsants / administration & dosage, Anticonvulsants / therapeutic use, Bone Marrow / drug effects, Bone Marrow / physiology, Carbamazepine / administration & dosage, Carbamazepine / therapeutic use, Down Syndrome, Drug Administration Schedule, Female, Humans, Time Factors, Valproic Acid / administration & dosage, Valproic Acid / therapeutic use, Anticonvulsants, Carbamazepine, Valproic Acid

A 38-year-old woman presented with acute hematological toxicity from her anticonvulsants, even though she had been taking them for many years
Giant mixed Sertoli-Leydig-Granulosa sex cord tumor of the testis; clinical, histopathological, and radiological features: a case report
Authors: Sakher Tahaineh, Rawan Abu Mughli, Moayid Fallatah
Journal: Pan Afr Med J (2017)
Keywords: orchiectomy, sex cord-gonadal stromal tumors, testicular neoplasms
MeSH terms: Orchiectomy / methods, Sertoli-Leydig Cell Tumor / diagnosis, Sex Cord-Gonadal Stromal Tumors / diagnosis, Testicular Neoplasms / diagnosis, Case Reports, Adult, Humans, Male, Sertoli-Leydig Cell Tumor / pathology, Sertoli-Leydig Cell Tumor / surgery, Sex Cord-Gonadal Stromal Tumors / pathology, Sex Cord-Gonadal Stromal Tumors / surgery, Testicular Neoplasms / pathology, Testicular Neoplasms / surgery

Sex cord tumors of the testis in post pubertal men are rare. Mixed leydig-Sertoli-Granulosa sex cord tumors are exceptionally rare. To the best of our knowledge there are only three reported similar cases in the literature. We reported a case of a 27-year-old male who presented with huge left scrotal mass of 6-years duration. The gross tumor specimen after resection measured 11 cm in diameter. Histological examination revealed mixed sex cord stromal tumor. This case demonstrates the limited ability of accurate diagnostic determination preoperatively, with pathologic examination and immune-histochemical staining post-orchiectomy representing the only definitive means of diagnosis. It also highlights the unique radiological appearances of this tumor, which were not previously reported in literature.
A case series and literature review of infections due to Myroides spp.: identification of contributing factors and emerging antibiotic susceptibility trends
Authors: Uzair Khan, Ellora Pandey, Nageswari Gandham, Nikunja Das, Sahjid Mukhida, Sriram Kannuri, Shalini Bhaumik, Shahzad Mirza
Journal: Access Microbiol (2023)
Keywords: flavobacteriaceae infections, myroides, case report, catheter-related infections, multiple drug resistance
MeSH terms: Case Reports

Introduction:
Infections forby Myroides spp. can lead to significant morbidity and mortality, particularly in immunocompromised patients with underlying co-morbidities. Recent reports have highlighted its intrinsic and acquired drug resistance, making it a particularly challenging infectious agent to combat.
Methods:

Myroides spp. isolated and reported in clinically significant urine samples were considered for the study. Identification of the organism was done via the VITEK 2C system. Antibiotic susceptibility testing was done using both manual and automated methods following Clinical and Laboratory Standards Institute (CLSI) guidelines. Existing literature was searched on MEDLINE using PubMed.
Results:
We present a series of five catheter-associated urinary tract infections due to Myroides odoratimimus , with sensitivity to only minocycline. This is the first case from Western India, and the third case in the existing literature that shows Myroides sensitivity only to minocycline. Our literature review is the first to systematically describe contributory factors to infection, allowing us to devise a clinically relevant tool that delineates contributory factors and efficacious drugs in Myroides spp. infection.
Conclusion:

Myroides spp. infections, previously considered rare and opportunistic, need cognizance and diagnostic suspicion especially in particular associated conditions.
A Case of Hypersexuality in a Patient Receiving Aripiprazole for Schizophrenia
Authors: Lakshmi Priya, Bini Moorthy
Journal: Case Rep Psychiatry (2021)
MeSH terms: Case Reports

Aripiprazole is an antipsychotic with partial agonist activity at the dopamine D2 receptor which may lead to compulsive behaviors including hypersexuality. The case presented is of a 24-year-old male with schizophrenia who developed hypersexuality symptoms after initiation of aripiprazole. Cessation of the aripiprazole led to a reduction in hypersexual behaviors. Clinicians should be aware of compulsive behaviors including hypersexuality with aripiprazole use and consider discontinuation of aripiprazole treatment in patients suffering from hypersexuality.
Acetabular liner dissociation: A case report and review of the literature
Authors: Asif A H Parkar, Mohamed Sukeik, Ahmed El-Bakoury, James Powell
Journal: SICOT J (2019)

Dissociation of the polyethylene liner from the acetabular shell is a rare but catastrophic complication of total hip arthroplasty (THA). There have been reports of polyethylene liner dissociation (PLD) as well as ceramic liner dissociation (CLD) in the literature. Amongst the commonly used implants, liner dissociation has been reported with the Pinnacle (DePuy), Harris-Galante (Zimmer) and Trident (Stryker) acetabular components. To the best of our knowledge, this is the first case report of PLD in an R3 (Smith & Nephew) acetabular component. This case report highlights the implant choice for treatment of the liner dissociation and the role of constrained implants in such cases.
Mckusick-kaufman syndrome presenting as acute intestinal obstruction
Authors: Ramesh B Hatti, Ashok V Badakali, R N Vanaki, Mahantesh S Samalad
Journal: J Neonatal Surg (2013)
Keywords: hydrometrocolpos, mckusick-kaufman syndrome, neonatal intestinal obstruction
MeSH terms: Case Reports

Hydrometrocolpos and polydactyly have been associated with many syndromes and can present at any age. Rarely does hydrometrocolpos present as neonatal intestinal obstruction. We report two cases of McKusick-Kaufman syndrome presenting with intestinal obstruction. In both cases, intestinal obstruction got relieved after a cutaneous vaginostomy.
Large mobile thrombus in non-atherosclerotic thoracic aorta as the source of peripheral arterial embolism
Authors: Nasser M Malyar, Rolf A Janosi, Zoran Brkovic, Raimund Erbel
Journal: Thromb J (2005)

The presence of thrombi in the atherosclerotic and/or aneurysmatic aorta with peripheral arterial embolism is a common scenario. Thrombus formation in a morphologically normal aorta, however, is a rare event. A 50 years old woman was admitted to the mergency department for pain, coldness, and anesthesia in the the left foot. She had a 25 years history of cigarette smoking, a history of postmenopausal hormone replacement therapy (HRT), hypercholesterolemia and hyperfibrinogenemia. An extensive serologic survey for hypercoagulability, including antiphospholipid antibodies, and vasculitis disorders was negative. Transesophageal echocardiography revealed a large, pedunculated and hypermobile thrombus attached to the aortic wall 5 cm distal of the left subclavian artery. The patient was admitted to the surgery department, where a 15 cm long fresh, parietal thrombus could be removed from the aorta showing no macroscopic wall lesions or any other morphologic abnormalities. This case report demonstrates the possibility of evolving a large, pedunculated thrombus in a morphologically intact aorta in a postmenopausal woman with thrombogenic conditions such as hyperfibrinogenemia, hypercholesterolemia, smoking and HRT. For these patients, profiling the individual risk and weighing the benefits against the potential risks is warranted before prescribing HRT.
The specific sagittal magnetic resonance imaging of intradural extra-arachnoid lumbar disc herniation
Authors: Tatsuro Sasaji, Kiyoshi Horaguchi, Noboru Yamada, Kazuo Iwai
Journal: Case Rep Med (2012)
MeSH terms: Case Reports

Intradural extra-arachnoid lumbar disc herniation is a rare disease. Few MRI findings have been reported. We experienced an intradural extra-arachnoid lumbar disc herniation. We reviewed the preoperative MRI findings. Lumbar spine T2-weighted sagittal MRI showed that one line of the ventral dura was divided into two by a disc herniation. We speculated that the two lines comprised the dura and arachnoid and that a disc herniation existed between them. We believe that division of the ventral dural line on T2-weighted sagittal images is a characteristic finding of intradural extra-arachnoid lumbar disc herniation. The division of ventral dural line seemed to be a "Y," and, thus, we called it the "Y sign." The "Y sign" may be useful for diagnosing intradural extra-arachnoid lumbar disc herniation.
De novo microduplication of CHL1 in a patient with non-syndromic developmental phenotypes
Authors: Orazio Palumbo, Rita Fischetto, Pietro Palumbo, Francesco Nicastro, Francesco Papadia, Leopoldo Zelante, Massimo Carella
Journal: Mol Cytogenet (2015)
MeSH terms: Case Reports

Background:
The CHL1 gene codes for a member of the L1 family of neural cell adhesion molecules. It is highly expressed in the central and peripheral nervous system playing an important role in the building and functioning on the brain. CHL1 proteins are also involved in axonal migration, synaptic formation and plasticity. In mice, functional studies showed that the haploinsufficiency of Chl1 gene in the developing brain results in cognitive deficits suggesting that the CHL1 gene at 3p26.3 is a candidate for an autosomal form of intellectual disability. Furthermore, in humans deletions of CHL1 have been described in patients with neurodevelopmental delay characterized by learning and language difficulties, seizures. Less is known about the potential effect of CHL1 overexpression, and microduplications of CHL1 have been rarely identified.
Case presentation:
In this report, we describe a male patient with a phenotype characterized by developmental delay, symptoms of hyperactivity, short attention span and speech delay. In addition, minor facial dysmorphic features have been observed. Chromosomal microarray analysis revealed a rare de novo 0.85 Mb microduplication on the short arm (p26.3) of chromosome 3, encompassing a single gene, CHL1. To the best of our knowledge, duplication of chromosome 3p26.3, including only the CHL1 gene, has been described in only one intellectually disabled girl with epilepsy. The duplication described here is the smallest reported so far. In addition, this is the first report describing a patient in which the CHL1 duplication is a de novo event.
Conclusions:
The clinical and molecular findings reported here are useful to provide further evidence that CHL1 is a dosage sensitive gene suggesting that not only the deletion but also its duplication can cause non-syndromic neurodevelopmental phenotypes.
Hepatorenal syndrome with cirrhotic cardiomyopathy: case report and literature review
Authors: Luis Mocarzel, Pedro Lanzieri, Juliana Nascimento, Clara Peixoto, Mário Ribeiro, Evandro Mesquita
Journal: Case Reports Hepatol (2015)

The hepatorenal syndrome (HRS) is defined as a potentially reversible kidney failure in patients with cirrhosis and ascites. An association of HRS and cirrhotic cardiomyopathy has been reported recently, but there are no result studies about the use of positive inotropes as part of the acute phase treatment. We report the case of a patient diagnosed with HRS, with high levels of NT pro-BNP, but with normal ejection fraction of the left ventricle, which showed abnormalities in systolic function through speckle tracking in echocardiography, reversible after the infusion of dobutamine. The patient showed clinical and laboratory improvement of his renal function after the infusion of dobutamine. Clinical studies are needed on HRS therapeutic approach taking into account the myocardial dysfunction as a major contributing factor to renal dysfunction.
Acromion fracture and lateral angle of the scapula spine: Case report and literature review
Authors: Sara Ribeiro Nunes, Marcos Rassi Fernandes Filho, Marcos Rassi Fernandes
Journal: Int J Surg Case Rep (2019)
Keywords: acromion, diagnosis by image, fracture fixation, shoulder blade, shoulder injuries

Introduction:
Scapular fractures are uncommon and correspond to 0.5-1% of all body fractures. The study objective was to present a rare case report of a fracture (lateral acromion and angle of the scapula spine) and review of the literature on which will greatly contribute to diagnosis and treatment.
Presentation of case:
A 74-year-old female patient with comminuted fracture of the acromial process and lateral angle of the spine of the scapula with subacromial space. The patient underwent surgical treatment with open reduction and use of blocked plaque, two plain Steinmann wires 2.0 and local bone graft.
Discussion:
Segmental fracture of acromion and spine of the scapula needs early diagnosis for the proper treatment. In our case report, the patient presented fracture of the acromion and lateral angle of the spine of the scapula, classified as Ogawa 1 and 3; Kunt 3; and AO A1, respectively.
Conclusion:
Segmental fracture of the acromion and lateral angle of the spine of the scapula with subacromial space reduction requires surgical intervention in order to avoid secondary complications. Early diagnosis favors better prognosis.
Atypical Presentation of Lemierre's Syndrome Causing Septic Shock and Acute Respiratory Distress Syndrome
Authors: Divyesh Reddy Nemakayala, Manoj P Rai, Shilpa Kavuturu, Supratik Rayamajhi
Journal: Case Rep Infect Dis (2018)
MeSH terms: Case Reports

Lemierre's disease is a rare but life-threatening condition characterized by an oropharyngeal infection complicating with thrombophlebitis of the internal jugular vein and disseminated abscesses. We are presenting a case of a young female who initially presented with fevers, chills, sore throat, and swollen neck later developed progressively worsening shortness of breath along with sudden onset pleuritic chest pain. She then developed progressively worsening acute hypoxic respiratory failure requiring intubation and mechanical ventilation. Interval chest X-ray showed worsening bilateral effusions. She also developed septic shock requiring pressors. Blood culture showed Fusobacterium, and antibiotics were changed accordingly following which there was a clinical improvement. The diagnosis of Lemierre's syndrome was then established based on her presenting age and bilateral pulmonary empyema in the setting of septicemia with Fusobacterium.
Hypokalemia-Induced Rhabdomyolysis as a result of Distal Renal Tubular Acidosis in a Pregnant Woman: A Case Report and Literature Review
Authors: Manasawee Srisuttayasathien
Journal: Case Rep Obstet Gynecol (2015)

Rhabdomyolysis in pregnancy is a rare occurrence. The manifestation of distal renal tubular acidosis (RTA) for the first time during adulthood is uncommon. According to a review of the literature, pregnancy may predispose individuals to rhabdomyolysis due to hypokalemia. A reduction in interstitial potassium ions could decrease muscular blood flow and lead to muscle injury. This report describes the case of a pregnant woman with rhabdomyolysis induced by hypokalemia resulting from distal RTA. The patient subsequently delivered a healthy newborn.
Small cell ovarian cancer in adolescents: report of two cases and review of the literature
Authors: M Rovithi, A G Pallis, A Kalykaki, E Lagoudaki, L Giannikaki, E N Stathopoulos, K Relakis, V Georgoulias
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

Ovarian small cell carcinoma is a rare and highly malignant neoplasm carrying a poor prognosis. Although combination chemotherapy remains the cornerstone of treatment due to the rarity of these tumors, no regimen can be recommended as standard of care although in the majority of cases platinum-based regimens are used. Herein, we report two cases of small cell carcinoma of the ovaries along with a review of the relevant literature.
Case Report: Bow Hunter Syndrome-One Reason to Add Non-gravity Dependent Positional Nystagmus Testing to Your Clinical Neuro-Otologic Exam
Authors: Michael C Schubert, Nathaniel Carter, Sheng-Fu Larry Lo
Journal: Front Neurol (2021)
Keywords: bow hunter's syndrome, downbeat nystagmus, neurological examination, positional nystagmus, positional vertigo
MeSH terms: Case Reports

This case study describes transient downbeat nystagmus with vertigo due to a bilateral Bow Hunters Syndrome that was initially treated for 7 months as a peripheral benign paroxysmal positional vertigo. Normal static angiography and imaging studies (magnetic resonance, computed tomography) contributed to the mis-diagnosis. However, not until positional testing with the patient in upright (non-gravity dependent) was a transient downbeat nystagmus revealed with vertigo. The patient was referred for neurosurgical consult. Unfortunately, surgery was delayed due to suicidal ideation and hospitalization. Eventually, vertigo symptoms resolved following a C4-5 anterior cervical dissection and fusion. This case highlights the critical inclusion of non-gravity dependent position testing as an augment to the positional testing component of the clinical examination as well as the extreme duress that prolonged positional vertigo can cause.
Xylitol toxicosis and serotonin-like syndrome occurring simultaneously in a dog secondary to ingestion of Natrol 5-HTP Fast Dissolve Tablets
Authors: Jennifer M Ortolani, Tara J Bellis, Michelle D Griego
Journal: Clin Case Rep (2018)
Keywords: natrol 5‐htp, canine, serotonin‐like syndrome, veterinary, xylitol toxicosis
MeSH terms: Case Reports

Xylitol and serotonergic compounds are included in the manufacture of numerous over-the-counter products. Both compounds have been documented to cause toxicosis in dogs. This report details the first case of simultaneous xylitol toxicosis and serotonin-like syndrome in a dog, secondary to ingestion of a single over-the-counter product.
Incidental Finding of Dextrocardia with Situs Inversus in a 59-Year-Old Man
Authors: Emmanuel Kobina Mesi Edzie, Klenam Dzefi-Tettey, Obed Cudjoe, Philip Narteh Gorleku, Patrick Adu
Journal: Case Rep Radiol (2019)
MeSH terms: Case Reports

Dextrocardia with situs inversus is a rare congenital anomaly, which is characterized by right-sided heart apex and inversely rotated visceral organs of the abdomen. We report an unusual case of dextrocardia with situs inversus in a 59-year-old man, referred for a pelvic ultrasound scan because of symptoms of lower urinary tract obstruction and after a fairly normal prostate specific antigen (PSA) value. A diagnosis of enlarged prostate gland with a prominent median lobe and significant residual urine volume was made, which necessitated the examination of the kidneys for hydronephrosis, resulting in the incidental finding of situs inversus. On further investigation, the diagnosis of dextrocardia with situs inversus was made. Physicians should look out for this anomaly primarily because it may be associated with other conditions like primary ciliary dyskinesia so appropriate interventions are offered to reduce morbidities and mortality.
A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma ("the Bad Kind" of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report
Authors: A Santoro, G Pannone, M Contaldo, F Sanguedolce, V Esposito, R Serpico, L Lo Muzio, S Papagerakis, P Bufo
Journal: J Skin Cancer (2011)
MeSH terms: Case Reports

Verrucous carcinoma (also known as Ackerman tumor) is an uncommon exophytic low-grade well-differentiated variant of squamous cell carcinoma. This neoplasm typically involves the oral cavity, larynx, genitalia, skin, and esophagus. It is well known for its locally aggressiveness and for its clinically slow-growing behaviour with minimal metastatic potential. Verrucous carcinoma of oral cavity is so closely aligned with the use of snuff and chewing tobacco that it has been called the "snuff dipper's cancer". Recent studies have proved the role of HPV. The typical clinical presentation of oral verrucous carcinoma has long been known, as its remarkably innocuous appearance and biological behaviour. In this work, we report a review of the scientific literature and describe a troublesome case of oral verrucous cancer.