OpenMed/multicare-articles huggingface dataset:
Systemic Lupus Erythematosus Presenting as Myopericarditis with Acute Heart Failure: A Case Report and Literature Review
Authors: Richard Jesse Durrance, Malahat Movahedian, Worku Haile, Katerina Teller, Richard Pinsker
Journal: Case Rep Rheumatol (2019)
MeSH terms: Case Reports

Acutely decompensated dilated cardiomyopathy in a middle-aged patient without the typical risk factor profile presents a clinical dilemma. While cardiomyopathy is a known aspect of systemic lupus erythematosus (SLE), initial clinical presentation as decompensated dilated cardiomyopathy (DCM) is exceedingly rare in the literature. We share the case of a 49-year-old African-American female with no past medical history who presented with overt heart failure of 4 weeks evolution. Workup showed acute onset decompensated dilated cardiomyopathy, with a serologic profile compatible with SLE. She responded well to immunosuppressive steroid therapy. Literature review for SLE presenting as dilated cardiomyopathy with acute heart failure revealed a paucity of clinical evidence and consensus. Therefore, a comprehensive review of case reports was undertaken. A total of 10 cases were identified. Patients were 90% female and averaged 31 years of age. Dyspnea was the most common clinical presentation, and dilated cardiomyopathy with severely compromised left ventricular function was universally appreciated. Clinical presentation to diagnosis averaged 2 weeks. Immunosuppressive therapy regimens were universally employed; however, the regimens varied significantly. High-dose steroid therapy was most commonly used, and clinical and functional recovery was reported in 90% of individual case reports. Within the limited evidence and experience of therapeutic approaches, the efficacy of different singular or combined therapy is based solely on anecdotal case reports. Given the near-complete response to a short course of high-dose steroid therapy as much in the clinical recovery as in the resolution of DCM, the limited evidence based on review of these observational case studies and series supports the initial use of high-dose steroid therapy in acute lupus myocarditis.
Thoracoscopic enucleation of esophageal leiomyoma in patient with MEN I syndrome
Authors: Waleed N Saleh, Ahmed Bamosa, Hadi Al-Mutairi, Khaled M Al-Kattan
Journal: Ann Thorac Med (2010)
Keywords: enucleation, leiomyoma, thoracosocpy
MeSH terms: Case Reports

Minimal invasive thoracic surgery is growing rapidly and may become the standard of care for certain diseases. Its benefits over traditional surgery, including reduced morbidities and hospital stay, have been well established in several reports. We herein report a case of midesophageal leiomyoma in a patient with MEN I syndrome successfully enucleated by thoracoscopy highlighting the technical details of the procedure.
Muscle weakness and myalgia as the initial presentation of serous ovarian carcinoma: a case report
Authors: Kyung-Jin Min, Yung-Taek Ouh, Hye-Ri Hong, Kyeong-A So, Jin Hwa Hong, Jae-Kwan Lee
Journal: J Ovarian Res (2014)
Keywords: ovarian carcinoma, paraneoplastic necrotizing myopathy
MeSH terms: Muscle Weakness / diagnosis, Myalgia / diagnosis, Neoplasms, Cystic, Mucinous, and Serous / diagnosis, Ovarian Neoplasms / diagnosis, Rectal Neoplasms / diagnostic imaging, Case Reports, Female, Humans, Lymphatic Metastasis, Middle Aged, Muscle Weakness / etiology, Muscular Diseases / diagnosis, Muscular Diseases / etiology, Myalgia / etiology, Necrosis / diagnosis, Necrosis / etiology, Neoplasm Invasiveness, Neoplasms, Cystic, Mucinous, and Serous / complications, Neoplasms, Cystic, Mucinous, and Serous / secondary, Ovarian Neoplasms / complications, Ovarian Neoplasms / pathology, Radiography, Rectal Neoplasms / complications, Rectal Neoplasms / secondary

Introduction:
Epithelial ovarian cancer (EOC) has one of the worst prognoses among gynecologic cancers. An appropriate screening method is not available for EOC, and the initial symptoms such as abdominal pain or bloating, anorexia, and urinary urgency are vague. As a result, most cases of EOC are diagnosed at an advanced stage.
Case presentation:
We report novel insights gained from the case of a 45-year-old, gravida 0, para 0 woman who presented to the emergency department with complaints of general weakness, fatigue, and myalgia over the previous two months. She reported progressive muscle weakness of the upper and lower extremities leading to difficulty walking. Serum muscle enzymes, such as creatine phosphokinase, were markedly elevated. No evidence of malignancy was detected upon imaging. A biopsy of the left vastus medialis muscle was performed, and the results were consistent with primary myopathy with myofibrillar disarray, suggesting paraneoplastic necrotizing myopathy. Explorative laparotomy was performed to evaluate these results, and histopathological analysis of the full specimen revealed a grade 3 ovarian serous adenocarcinoma with direct invasion to the rectum.
Conclusions:
Because of the lack of screening tools for EOC, any clinical findings suggesting its presence are valuable, and the possibility of EOC should be considered in unknown primary malignancies with initial complaints of muscle weakness or myalgia.
Adult active transport in the Netherlands: an analysis of its contribution to physical activity requirements
Authors: Elliot Fishman, Lars Böcker, Marco Helbich
Journal: PLoS One (2015)
MeSH terms: Bicycling / statistics & numerical data, Exercise / physiology, Transportation / statistics & numerical data, Travel / statistics & numerical data, Walking / statistics & numerical data, Adolescent, Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Motor Activity, Netherlands, Sedentary Behavior, Young Adult

Introduction:
Modern, urban lifestyles have engineered physical activity out of everyday life and this presents a major threat to human health. The Netherlands is a world leader in active travel, particularly cycling, but little research has sought to quantify the cumulative amount of physical activity through everyday walking and cycling.
Methods:
Using data collected as part of the Dutch National Travel Survey (2010 - 2012), this paper determines the degree to which Dutch walking and cycling contributes to meeting minimum level of physical activity of 150 minutes of moderate intensity aerobic activity throughout the week. The sample includes 74,465 individuals who recorded at least some travel on the day surveyed. As physical activity benefits are cumulative, all walking and cycling trips are analysed, including those to and from public transport. These trips are then converted into an established measure of physical activity intensity, known as metabolic equivalents of tasks. Multivariate Tobit regression models were performed on a range of socio-demographic, transport resources, urban form and meteorological characteristics.
Results:
The results reveal that Dutch men and women participate in 24 and 28 minutes of daily physical activity through walking and cycling, which is 41% and 55% more than the minimum recommended level. It should be noted however that some 57% of the entire sample failed to record any walking or cycling, and an investigation of this particular group serves as an important topic of future research. Active transport was positively related with age, income, bicycle ownership, urban density and air temperature. Car ownership had a strong negative relationship with physically active travel.
Conclusion:
The results of this analysis demonstrate the significance of active transport to counter the emerging issue of sedentary lifestyle disease. The Dutch experience provides other countries with a highly relevant case study in the creation of environments and cultures that support healthy, active living.
Metal-on-Metal Hip Retrieval Analysis: A Case Report
Authors: Thomas B Pace, Kara A Rusaw, Lawrence J Minette, Brayton R Shirley, Rebecca G Snider, John D Desjardins
Journal: Case Rep Orthop (2013)

This is a case report involving a single case with severe bone and soft tissue destruction in a young male patient with a 10-year-metal on-metal total hip arthroplasty. Following complete aseptic erosion of the affected hip greater trochanter and abductor muscles, the hip was revised for recurrent instability. Histological examination of the patient's periprosthetic tissues, serological studies, and review of recent medical reports of similar cases were used to support an explanation of the destructive process and better contribute to our understanding of human reaction to metal debris in some patients following metal-on-metal hip arthroplasty.
The rhinolith-a possible differential diagnosis of a unilateral nasal obstruction
Authors: Detlef Brehmer, Randolf Riemann
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

Rhinoliths are mineralised foreign bodies in the nasal cavity that are a chance finding at anterior rhinoscopy. Undiscovered, they grow appreciably in size and can cause a foul-smelling nasal discharge and breathing problems. Giant nasal stones are now a very rare occurrence, since improved diagnostic techniques, such as endoscopic/microscopic rhinoscopy, now make it possible to identify foreign bodies at an early stage of development. We report the case of a 37-year-old patient who, at the age of 5-6 years, introduced a foreign body, probably a stone, into his right nasal cavity. On presentation, he complained of difficulty in breathing through the right nostril that had persisted for the last 10 years. For the past four years a strong fetid smell from the nose had been apparent to those in his vicinity. Under general anaesthesia, the stone was removed in toto from the right nasal cavity. The possible genesis of the rhinolith is discussed, our case compared with those described in the literature, and possible differential diagnoses are considered.
Symptomatic Mixed Cryoglobulinemia during HIV Primary Infection: A Case Report
Authors: Philippe Genet, Laurence Courdavault, Bouchra Wifaq, Juliette Gerbe
Journal: Case Rep Infect Dis (2011)
MeSH terms: Case Reports

We report a patient who developed during HIV primary infection a symptomatic mixed cryoglobulinemia. The patient suffered from arthralgias, vascular purpura of the legs, and proteinuria. Cryoglobulinemia progressively disappeared in several months after HAART.
A case of spontaneous pneumothorax due to paragonimiasis in North America with literature review
Authors: Seung Ah Kang, Parag Kumar Patel, Sachin Patil, Andres Bran-Acevedo, Lester Layfield, Sebastian Wiesemann, William Roland
Journal: IDCases (2023)
Keywords: lung fluke, north america, paragonimiasis, paragonimus kellicotti, parasitic lung infection
MeSH terms: Case Reports

The species, Paragonimus kellicotti , causes human paragonimiasis in North America. As a foodborne disease, human infection with P. kellicotti occurs after eating raw or undercooked crayfish containing metacercariae. Many risk factors have been described in the literature, including young adult age, male, alcohol consumption, outdoor activities involving rivers within Missouri, and ingesting raw or partially cooked crayfish. Here, we report a case of a 41-year-old male with a 5-year history of cough who presented with acute shortness of breath. Further workup showed mild eosinophilia and spontaneous pneumothorax. A definitive diagnosis was made with a lung biopsy, which showed P. kellicotti eggs. Further questioning revealed that the patient took a hunting and river rafting trip on a river in Missouri 5 years ago, though the history was negative for any crayfish consumption. Paragonimiasis should be considered in those with associated clinical features, including cough and eosinophilia, with a history of a river raft float trip in Missouri, even if the history is negative for crayfish ingestion or travel.
Adhesion Ileus after Fecal Microbiota Transplantation in Long-Standing Radiation Colitis
Authors: Igor Alexander Harsch, Peter Christopher Konturek
Journal: Case Rep Gastrointest Med (2019)
MeSH terms: Case Reports

Fecal microbiota transplantation (FMT) is a novel strategy for the therapy of dysbiosis-associated disorders via modulation of the gut microbiota. Intestinal dysbiosis is associated not only with digestive disorders, but also with a variety of extra-digestive disorders. A worldwide increasing number of FMT can be expected in the future as well as an increase in adverse events. We describe the case of a patient with chronic radiation colitis that developed adhesion ileus 2 days after FMT. Since these problems never occured before and the short time interval favours a causality, we speculate about FMT-induced alterations in gut motility causing a "trapping" of the small intestine in an adhesion and other mechanisms beyond "pure" coincidence.
Postauricular leiomyosarcoma: a case report and literature review
Authors: Dillip Samal, Rajeev Kumar, Saumyaranjan Mallick, Alok Thakar
Journal: Case Rep Otolaryngol (2013)

Leiomyosarcoma arising in the head and neck region is a rare entity. Auricular involvement by the disease is further rarer with few cases reported in the literature. Usually auricular leiomyosarcoma is a disease of middle-old age. We report a case of leiomyosarcoma of the postauricular region in a young adolescent female. Surgery along with adjuvant radiotherapy was used for complete cure. Patient is disease-free for the last eight years and is on regular yearly followup. The aim of reporting this case is to add to the scarce existing literature regarding auricular leiomyosarcoma and its long-term outcome. Also, this is the first case report in young adolescent and second only of the post auricular region.
Prophylactic platelets in dengue: survey responses highlight lack of an evidence base
Authors: James Whitehorn, Rosmari Rodriguez Roche, Maria G Guzman, Eric Martinez, Wilmar Villamil Gomez, Leonard Nainggolan, Ida Safitri Laksono, Ajay Mishra, Lucy Lum, Abul Faiz, Amadou Sall, Joshua Dawurung, Alvaro Borges, Yee-Sin Leo, Lucille Blumberg, Daniel G Bausch, Axel Kroeger, Olaf Horstick, Guy Thwaites, Heiman Wertheim, Mattias Larsson, Tran Tinh Hien, Rosanna Peeling, Bridget Wills, Cameron Simmons, Jeremy Farrar
Journal: PLoS Negl Trop Dis (2012)
MeSH terms: Dengue / complications, Dengue / therapy, Platelet Transfusion / methods, Thrombocytopenia / therapy, Case Reports, Research Support, Non-U.S. Gov't, Adolescent, Adult, Blood Platelets, Female, Humans, Male, Surveys and Questionnaires, Treatment Outcome, Young Adult

Dengue is the most important arboviral infection of humans. Thrombocytopenia is frequently observed in the course of infection and haemorrhage may occur in severe disease. The degree of thrombocytopenia correlates with the severity of infection, and may contribute to the risk of haemorrhage. As a result of this prophylactic platelet transfusions are sometimes advocated for the prevention of haemorrhage. There is currently no evidence to support this practice, and platelet transfusions are costly and sometimes harmful. We conducted a global survey to assess the different approaches to the use of platelets in dengue. Respondents were all physicians involved with the treatment of patients with dengue. Respondents were asked that their answers reflected what they would do if they were the treating physician. We received responses from 306 physicians from 20 different countries. The heterogeneity of the responses highlights the variation in clinical practice and lack of an evidence base in this area and underscores the importance of prospective clinical trials to address this key question in the clinical management of patients with dengue.
The use of tissue plasminogen activator as continuous infusion into an arteriovenous hemodialysis access in the hemodialysis unit: a case series
Authors: Elene van der Merwe, Rick Luscombe, Mercedeh Kiaii
Journal: Can J Kidney Health Dis (2015)
Keywords: arteriovenous dialysis fistula, continuous infusion, dialysis unit, tissue plasminogen activator

Background:
Thrombolytics such as tissue plasminogen activator are often used by interventional radiologists in the radiology suite to salvage thrombosed hemodialysis arteriovenous fistulae. Thrombolytics are also commonly used in dialysis facilities as a dialysis catheter lock solution or as an infusion into a dialysis catheter when dysfunctional. However, the use of tissue plasminogen activator as a continuous infusion into an arteriovenous fistula in the dialysis facility to treat clot burden is not commonly done.
Objective:
The aim of our case series is to demonstrate the successful use of tissue plasminogen activator to decrease clot burden in an arteriovenous fistula in the dialysis unit.
Design:
Observational case series.
Setting:
An outpatient dialysis facility in a tertiary care hospital.
Patients:
Three non- consecutive patients were diagnosed with an acute thrombosed arteriovenous fistula either on physical exam or by imaging.
Measurements:
A thrombosed fistula as well as successful resolution of clot was illustrated by either physical exam, fistulogram or ultrasound. A functioning fistula demonstrated successful continuation of dialysis and adequate access flow measurements in follow up.
Method:
This is a case series that describes the technique of using an infusion of tissue plasminogen activator into an arteriovenous fistula on the dialysis unit by vascular access nurses to treat or diminish clot burden.
Results:
We have described three separate cases where treatments with tissue plasminogen activator infusions on the dialysis unit resulted in objective evidence of decrease in clot burden on ultrasound or fistulogram.
Limitations:
The small numbers of our case series requires that the results need to be verified in a larger study. Inclusion and exclusion criteria need to be defined before widespread application of this technique.
Conclusions:
To our knowledge this small case series is the first to describe the procedure whereby low dose tissue plasminogen activator is directly infused into the fistula by the vascular access nurse in the dialysis unit during dialysis and not in the interventional suite. This provides additional information to the existing literature that there is an alternative option for dialysis units to diminish clot burden until a more permanent solution is established through angioplasty.
A Giant-Cell Lesion with Cellular Cannibalism in the Mandible: Case Report and Review of Brown Tumors in Hyperparathyroidism
Authors: Lorenzo Azzi, Laura Cimetti, Matteo Annoni, Diego Anselmi, Lucia Tettamanti, Angelo Tagliabue
Journal: Case Rep Dent (2017)
MeSH terms: Case Reports

A small radiolucent area in the mandible was discovered in a 58-year-old woman with no oral complaints. The patient's history included only hypertension. The lesion was considered as an inflammatory cyst and was enucleated. Three months later, a CT revealed the presence of a cyst-like lesion in the mandible with thin expanded buccal cortical plate, localized erosion, and a polylobate appearance on the lingual aspect of the cortical plate. The histological diagnosis of the lesion was central giant-cell granuloma (CGCG). The lesion was thoroughly enucleated. Nevertheless, another X-ray carried out six months later revealed multiple bilateral osteolytic areas throughout the jaw. In addition, widespread cortical plate erosion was observed, as well as signs of root resorption and periodontal enlargement. There was no sign of neurological involvement, although the nerves appeared to be dislocated. After full blood chemistry analysis and detailed collection of radiographs, the final diagnosis was brown tumors in primary hyperparathyroidism. This case report demonstrates how dental clinicians may be the first-line specialists who identify a complex systemic disease before other clinicians. Finally, it highlights the role of cellular cannibalism in predicting the clinical aggressiveness of brown tumors as well as in other giant-cell lesions.
Envenomation by the Green Bush Viper Atheris squamigera
Authors: Sam T Ontiveros, Priya Srihari, Garret A Winkler, Jake Del Rosso, Julia Sobel, Richard F Clark, Alicia B Minns
Journal: Toxicol Rep (2022)
Keywords: antivenin, antivenom, bush viper, venom
MeSH terms: Case Reports

The Green Bush Viper, Atheris squamigera, is native to West and Central Africa and has few well reported envenomations. Bite victims experience dizziness, nausea, headache, regional lymphadenopathy, and localized edema. Most reports also detail severe effects including thrombocytopenia, coagulopathy, hemolysis, hemorrhage, or renal failure. Fatalities are reported, but poorly described. There is no specific antivenom for A. squamigera, but non-species specific antivenom has been reported helpful in several cases. We report the case of a 36-year-old woman who was bitten by a green bush viper and was treated with several non-species specific antivenoms. There were no complications to antivenom administration and the patient experienced a milder envenomation than detailed in previous reports.
Primary squamous cell carcinoma of endometrium: case report and literature review
Authors: Fatima Zahra Farhane, Zineb Alami, Touria Bouhafa, Abderrahmane Elmazghi, Khalid Hassouni
Journal: Pan Afr Med J (2018)
Keywords: squamous cell carcinoma, endometrium, postmenopausal bleeding
MeSH terms: Carcinoma, Squamous Cell / diagnosis, Endometrial Neoplasms / diagnosis, Hysterectomy / methods, Case Reports, Review, Carcinoma, Squamous Cell / pathology, Carcinoma, Squamous Cell / therapy, Disease Progression, Endometrial Neoplasms / pathology, Endometrial Neoplasms / therapy, Female, Humans, Hysteroscopy / methods, Magnetic Resonance Imaging, Middle Aged, Neoplasm Staging, Prognosis

In this paper, we report a case of primary squamous cell carcinoma of the endometrium (PSCCE) with a literature review. A 64-year-old woman, was admitted because postmenopausal bleeding. The gynecological exam found bleeding from the endocervix. The pelvic ultrasound objectified uterine regular contours, endometrial thickened was 10 mm, the presence of an intra cavitary lesion mesuring 56/70 mm. The diagnostic hysteroscopy revealed a whitish appearance taking all the uterine cavity making evoke a tumor of the endometrium. Pelvic MRI showed a tumor limited to the uterine corpus endometrium (invasion by more than 50% of the myometrium) without invasion of the cervix. Radical hysterectomy, bilateral salpingo-oophorectomy, and lymph nodes dissection were performed. Grossly, the endometrial carcinoma was polypoid tumor occupying the entire uterine cavity. Histologically, the diagnosis of SCC was retained. No adenocarcinoma element was recognized. Neither squamous metaplasia nor dysplasia was recognized. No ectopic cervical tissue was found. The SCC was found to invade into deeper one half of the myometrium. No tumor cells were seen in other sites including the cervix, ovaries, parametres, and lymph nodes. The patients was FIGO 2009 stage IB (pT1B, N0), and was treated with adjuvant radiation. The patient had a disease progression in the pelvis 3 months after the irradiation. We reported a case of PSCCE which can help to enrich the literature for the treatment and prognosis of this disease.