OpenMed/multicare-articles huggingface dataset:
Quantitative effects of repeated muscle vibrations on gait pattern in a 5-year-old child with cerebral palsy
Authors: Filippo Camerota, Manuela Galli, Claudia Celletti, Sara Vimercati, Veronica Cimolin, Nunzio Tenore, Guido M Filippi, Giorgio Albertini
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

Objective. To investigate quantitatively and objectively the effects of repeated muscle vibration (rMV) of triceps surae on the gait pattern in a 5-year-old patient with Cerebral Palsy with equinus foot deformity due to calf spasticity. Methods. The patient was assessed before and one month after the rMV treatment using Gait Analysis. Results. rMV had positive effects on the patient's gait pattern, as for spatio-temporal parameters (the stance duration and the step length increased their values after the treatment) and kinematics. The pelvic tilt reduced its anteversion and the hip reduced the high flexion evidenced at baseline; the knee and the ankle gained a more physiological pattern bilaterally. The Gillette Gait Index showed a significant reduction of its value bilaterally, representing a global improvement of the child's gait pattern. Conclusions. The rMV technique seems to be an effective option for the gait pattern improvement in CP, which can be used also in very young patient. Significant improvements were displayed in terms of kinematics at all lower limb joints, not only at the joint directly involved by the treatment (i.e., ankle and knee joints) but also at proximal joints (i.e., pelvis and hip joint).
Pilomatrixoma in the cheek: a clinical case report
Authors: Mario Vitor Carcassola, Wladimir Gushiken de Campos, Celso Augusto Lemos, Basilio de Almeida Milani, Ricardo Luiz Psciolaro, Marcelo Minharro Ceccheti
Journal: Autops Case Rep (2022)
Keywords: neoplasms, oral surgery, pathology, pilomatrixoma, skin neoplasms
MeSH terms: Case Reports

Pilomatrixoma is a follicular benign tumor of unknown etiology that originates in the matrix of a hair follicle. It develops more frequently in children and young adults, with a slight predominance in female patients. It is a slow-growing tumor that presents as a mobile nodule, firm, and with well-defined borders. The present study aimed to report the clinical, histopathologic, and radiographic aspects of pilomatrixoma in the cheek area of a 20-year-old female patient as the established treatment at an oral maxillofacial department. Pilomatrixoma is rarely included in the differential diagnosis of masses and nodules in the skin, and it is often confused with other nodular lesions, such as epidermoid cysts. The diagnostic method to identify this entity is an incisional biopsy. Because of its high incidence in the head and neck region, oral surgeons should be well-acquainted with this type of tumor so that it can be included as a diagnostic hypothesis of masses and nodules of the head and neck.
X-Linked retinoschisis associated to a novel intragenic microdeletion: case report
Authors: Clara Vazquez-Alfageme, Roberto Reinoso, Alberto Acedo, Rosa M Coco
Journal: BMC Med Genet (2016)
MeSH terms: Retinoschisis / diagnosis, Retinoschisis / genetics, Case Reports, Adolescent, Eye Proteins / genetics, Genotype, Humans, Male, Mutation, Missense, Sequence Deletion, White People, Eye Proteins, RS1 protein, human

Background:
X-linked retinoschisis is a recessively inherited retinal degeneration. Clinical diagnosis can be challenging due to the highly variable phenotypic presentation. Also, clinical diagnostic tests may be normal at early stages of this condition. Therefore, genetic diagnosis has become a priceless tool in the management of this disease.
Case presentation:
We present a case of a 17-year-old caucasian male with foveal and peripheral schisis, along with Mizuo-Nakamura phenomenon. RS1 sequencing led to the discovery of an in-frame deletion not previously described in the literature.
Conclusions:
Genetic deletions causative of X-linked retinoschisis are quite rare, since more than 80 % are caused by misssense mutations. In this particular case, its pathological effect comes from affecting a key element of the retinoschisin, the discoidin domain.
Corticopuncture Facilitated Microimplant-Assisted Rapid Palatal Expansion
Authors: Selly Sayuri Suzuki, Laila Fernanda Souza Braga, Denise Nami Fujii, Won Moon, Hideo Suzuki
Journal: Case Rep Dent (2018)
MeSH terms: Case Reports

Introduction:
Microimplant-assisted rapid palatal expansion (MARPE) has been considered an alternative to avoid extensive surgical procedures. In order to obtain skeletal results of MARPE, force should be enough to overcome areas of resistance and the first one that is required to be disrupted is the midpalatal suture, which becomes increasingly interdigitated after adolescence.
Objective:
The present study aimed at providing a novel approach using a minimally invasive method called corticopuncture (CP) in association with MARPE illustrated by a case report of a 35-year-old Brazilian female Caucasian patient presenting maxillary transverse deficiency.
Method:
Treatment plan started with an orthopedic correction of the transverse problem using a MARPE device. After many unsuccessful attempts to activate MARPE, corticopunctures were performed along the midpalatal suture. CP procedure at the midpalatal suture included 8 perforations (2 mm apart), performed after previous predrilling followed by miniscrew insertion (5 mm thread length and 1.8 mm diameter).
Results:
After CP and new activation protocol, the opening of the midpalatal suture was observed by CBCT images, showing skeletal results, suture split of 3.14 mm (premolar area) and 2.06 (molar area), an increase of 4.3 mm (premolar) and 3.03 mm (molar) in basal bone width, 4.43 mm (premolar) and 3.1 mm (molar) in cortical bone width, and minimal dental effects (mean of 1.2° of tooth tipping).
Conclusion:
The combination of MARPE and corticopuncture method was proved to be a nonsurgical treatment option to correct maxillary transverse deficiency in an adult patient. CP was able to weaken suture interdigitation thus facilitating the split.
Emergence of Huntington Disease in a Man With a Premorbid Criminal Lifestyle
Authors: Jonatan Hedlund, Thomas Masterman
Journal: Front Psychiatry (2019)
Keywords: huntington disease, dementia, forensic psychiatry, psychosis, violence
MeSH terms: Case Reports

We present here a case in which Huntington disease (HD) was diagnosed upon forensic-psychiatric evaluation of a 34-year-old male repeat offender. Despite a family history of HD, as well as overt delusions and motor pathology, the disease had not been recognized at an earlier stage, and the patient was serving a prison sentence at the time of diagnosis. The case highlights difficulties court officials may face with regard to identifying severe psychiatric and neurological disorders in repeat offenders. Such offenders' gradually deteriorating status could be overlooked by the court, even in cases in which a tailored judicial process is warranted. Also, the present case highlights the risk of using antipsychotic medication to treat HD, since it may worsen sufferers' capacity to recognize emotions in others, thereby increasing the risk of altercations and criminal activity.
Chondroma of the Bladder: An Atypical Localization
Authors: M Tamayo-Jover, A Nazco-Deroy, R González-Álvarez, H Álvarez-Argüelles Cabrera, B Padilla-Fernández, T Concepción-Masip
Journal: Case Rep Urol (2017)
MeSH terms: Case Reports

Chondroma is a benign tumour of mesenchymal origin that is composed of cartilage and rarely located in soft tissues, being described so far only in four cases, as located in the bladder, according to our knowledge. We describe the fifth case of a 67-year-old woman who consulted for microscopic haematuria, with an endoscopic finding of submucosal nodular image in the anterior wall of the bladder, which after resection and the histologic study shows cartilage and fibroconnective tissue, in part hyalinised, and positive immunohistochemical staining of cells with vimentin and S-100; this fact can support the diagnosis of bladder chondroma.
Intradural Disk Herniation Mimicking a Spinal Tumor: Radiologic Imaging, Pathogenesis, and Operative Management
Authors: Daisuke Tateiwa, Ryoji Yamasaki, Rinsei Tei, Yasushi Shin, Kenta Ariga, Kenji Hayashida, Eiji Wada
Journal: Case Rep Orthop (2018)
MeSH terms: Case Reports

Intradural disk herniation (IDH) is a rare condition, occurring more often at the L4-5 level. We examined a case of an IDH at the L1-2 level mimicking an intradural spinal tumor. A 71-year-old woman with a long history of backache and pain radiating down the left leg was admitted to our hospital with the worsening of these symptoms. Magnetic resonance imaging and computed tomographic myelography demonstrated an intradural mass at the L1-2 level. Given the radiologic findings and the location of the mass, the preoperative differential diagnosis centered on intradural spinal tumors. Dural incision was performed using a surgical microscope to resect the mass. Contrary to our expectation, the diagnosis made during the surgery was IDH. Despite advances in imaging techniques, IDH could not be definitively diagnosed preoperatively. The pathogenesis of IDH remains unclear. In our patient, the ventral dural defect was smooth and round, and the dural tissue around the defect was thickened. These intraoperative findings suggested that the patient's IDH resulted not from an acute new event but from a chronic process. We recommend dural incision using a surgical microscope for treating IDH because it provides a clear visual field.
A wakeboarding injury presented as acute carpal syndrome and median nerve contusion after wrist strangulation: a case report
Authors: Karsten Knobloch, Andreas Gohritz, Mehmed A Altintas, Marcus Spies, Peter M Vogt
Journal: Cases J (2009)

Background:
We present a case of combined median nerve contusion with immediate loss of sensation after the strangulation with a wakeboarding rope and prolonged referral to our department 72 hours after the injury accompanied by an acute carpal tunnel syndrome with immediate relief of numbness of a significant proportion of the median nerve following surgical decompression.
Case presentation:
The palmar branch of the median nerve was surrounded by a significant haematoma in addition to the strangulation damage caused by its more superficial location in contrast to the median nerve.
Conclusion:
In case of acute median neuropathy, urgent surgical intervention with exploration, decompression of both, the median nerve and the superficial branch of the median nerve, accompanied by compartment measurements of the forearm should be performed to regain or re-establish neurological integrity.
Comparative performance of the BGISEQ-500 and Illumina HiSeq4000 sequencing platforms for transcriptome analysis in plants
Authors: Fu-Yuan Zhu, Mo-Xian Chen, Neng-Hui Ye, Wang-Min Qiao, Bei Gao, Wai-Ki Law, Yuan Tian, Dong Zhang, Di Zhang, Tie-Yuan Liu, Qi-Juan Hu, Yun-Ying Cao, Ze-Zhuo Su, Jianhua Zhang, Ying-Gao Liu
Journal: Plant Methods (2018)
Keywords: alternative splicing, bgiseq-500, differential expressed genes, illumina hiseq4000, next-generation sequencing, transcriptome

Background:
The next-generation sequencing (NGS) technology has greatly facilitated genomic and transcriptomic studies, contributing significantly in expanding the current knowledge on genome and transcriptome. However, the continually evolving variety of sequencing platforms, protocols and analytical pipelines has led the research community to focus on cross-platform evaluation and standardization. As a NGS pioneer in China, the Beijing Genomics Institute (BGI) has announced its own NGS platform designated as BGISEQ-500, since 2016. The capability of this platform in large-scale DNA sequencing and small RNA analysis has been already evaluated. However, the comparative performance of BGISEQ-500 platform in transcriptome analysis remains yet to be elucidated. The Illumina series, a leading sequencing platform in China's sequencing market, would be a preferable reference to evaluate new platforms.
Methods:
To this end, we describe a cross-platform comparative study between BGISEQ-500 and Illumina HiSeq4000 for analysis of Arabidopsis thaliana WT (Col 0) transcriptome. The key parameters in RNA sequencing and transcriptomic data processing were assessed in biological replicate experiments, using aforesaid platforms.
Results:
The results from the two platforms BGISEQ-500 and Illumina HiSeq4000 shared high concordance in both inter- (correlation, 0.88-0.93) and intra-platform (correlation, 0.95-0.98) comparison for gene quantification, identification of differentially expressed genes and alternative splicing events. However, the two platforms yielded highly variable interpretation results for single nucleotide polymorphism and insertion-deletion analysis.
Conclusion:
The present case study provides a comprehensive reference dataset to validate the capability of BGISEQ-500 enabling it to be established as a competitive and reliable platform in plant transcriptome analysis.
Oral verrucous carcinoma mimicking a chronic candidiasis: a case report
Authors: Natália Galvão Garcia, Denise Tostes Oliveira, João Adolfo Costa Hanemann, Alessandro Antônio Costa Pereira
Journal: Case Rep Oncol Med (2012)
MeSH terms: Case Reports

Verrucous carcinoma has a special propensity to mimic benign lesions of the oral cavity. A case of the oral verrucous carcinoma in maxillary alveolar ridge, extending to buccal vestibule, cheek, and labial mucosa, which was diagnosed and initially treated as chronic candidiasis, is presented. Clinical, histopathological, and therapeutic considerations related to diagnosis of the verrucous carcinoma in the oral cavity are discussed.
Sleep state misperception: is there a CNS structural source?
Authors: Giselle de Martin Truzzi, Igor de Lima Teixeira, Lucila Bizari Fernandes do Prado, Gilmar Fernandes do Prado, Sergio Tufik, Fernando Morgadinho Coelho
Journal: Sleep Sci (2021)
Keywords: acquired immunodeficiency syndrome, sleep, sleep initiation and maintenance disorders, toxoplasmosis, cerebral
MeSH terms: Case Reports

Introduction:
We describe a case of sleep state misperception in a patient with a neurotoxoplasmosis lesion in the left nucleocapsular region.
Case report:
A 40-year-old female patient presented relating sleeplessness over the past 2 years, concurrent with progressive headaches, dizziness and motor and sensory deficits in the right upper and lower limbs. She had a history of AIDS, on irregular antiretroviral therapy and neurotoxoplasmosis. A polysomnography confirmed the hypothesis of sleep state misperception, and magnetic resonance imaging revealed a residual lesion in the left nucleocapsular region.
Conclusion:
Different models consider that the sleep state misperception could be correlated to structural abnormalities of the central nervous system. A recent study showed that the medial prefrontal cortex had a lower activation in patients with unrefreshing sleep due to chronic fatigue syndrome. This case report highlights the possibility of sleep state misperception having - at least partially - an anatomical substrate in the left nucleocapsular region.
Liver resection after downstaging hepatocellular carcinoma with sorafenib
Authors: L Barbier, F Muscari, S Le Guellec, A Pariente, P Otal, B Suc
Journal: Int J Hepatol (2011)
MeSH terms: Case Reports

Background. Sorafenib is a molecular-targeted therapy used in palliative treatment of advanced hepatocellular carcinoma in Child A patients. Aims. To address the question of sorafenib as neoadjuvant treatment. Methods. We describe the cases of 2 patients who had surgery after sorafenib. Results. The patients had a large hepatocellular carcinoma in the right liver with venous neoplastic thrombi (1 in the right portal branch, 1 in the right hepatic vein). After 9 months of sorafenib, reassessment showed that tumours had decreased in size with a necrotic component. A right hepatectomy with thrombectomy was performed, and histopathology showed 35% to 60% necrosis. One patient had a recurrence after 6 months and had another liver resection; they are both recurrence-free since then. Conclusion. Sorafenib can downstage hepatocellular carcinoma and thus could represent a bridge to surgery. It may be possible to select patients in good general condition with partial regression of the tumour with sorafenib for a treatment in a curative intent.
Peroneal Nerve Palsy Caused by Proximal Fibular Solitary Osteochondroma: Case Report and Literature Review
Authors: Takashi Kozu, Masayoshi Machida, Katsuaki Taira, Noboru Oikawa, Naho Nemoto, Kazuyoshi Nakanishi
Journal: Case Rep Orthop (2022)
MeSH terms: Case Reports

Osteochondroma is a relatively common benign tumor of the bone, and compressive neuropathies due to osteochondroma are comparatively rare. Here, we present a rare case of osteochondroma of the fibular head that caused peroneal nerve palsy in an 8-year-old girl. Physical examination revealed 0/5 tibialis anterior, 1/5 extensor hallucis longus, and 1/5 peroneal brevis muscle power-according to the manual muscle testing grading system, as well as numbness on the lateral side of the right leg and the back of the foot. Radiological examination and ultrasound revealed a bone tumor in the head of the right fibula. Magnetic resonance imaging ruled out spinal nerve root compression. It was discovered that the bone tumor in the fibular head had compressed and displaced the common peroneal nerve. The patient underwent surgical decompression of the right peroneal nerve. A bone region measuring 22 × 14 × 8 mm was removed. Three months postoperatively, the preoperative neurological deficits were found to be nearly resolved. The patient presented with a foot drop for 1 year, but symptoms resolved 3 months after surgery. Conventional wisdom states that surgery should be performed within 3 months, but we recommend that surgery be performed as soon as diagnosis is made even in cases with a long history, as it may improve patient symptoms and outcomes.
Incidental Finding of Persistent Hydatidiform Mole in an Adolescent on Depo-Provera
Authors: Olukayode Akinlaja, Rebecca McKendrick, Zineb Mashak, May Nokkaew
Journal: Case Rep Obstet Gynecol (2016)
MeSH terms: Case Reports

Molar pregnancies represent an uncommon yet important obstetric problem with potentially fatal outcomes. Patients typically present with signs and symptoms of early pregnancy, and physicians most often suspect nonmolar pregnancy complications initially; however a hydatidiform mole should be included in the differential diagnosis of a woman with a positive pregnancy test and abnormal vaginal bleeding irrespective of the use of contraception. Our case is that of an adolescent female on Depo-Provera injectable contraceptive with increased vaginal bleeding, abdominal pain, nausea, and vomiting who was incidentally found to be pregnant and subsequently diagnosed with a molar pregnancy despite persistent denial of having initiated sexual intercourse. Though gestational trophoblastic disease is uncommon with an incidence of about 1-2 cases per 1,000 pregnancies, a clinician has to display a high index of suspicion when dealing with patients at extremes of age in order to avoid potentially life-threatening outcomes.
Blunt Trauma Associated With Bilateral Diaphragmatic Rupture: A Case Report
Authors: Marco Pace, Damiano Vallati, Elena Belloni, Marco Cavallini, Mohsen Ibrahim, Erino Angelo Rendina, Giuseppe Nigri
Journal: Front Surg (2021)
Keywords: covid-19, bilateral diaphragmatic rupture, blunt trauma, case report, emergency surgery, repair of diaphragm
MeSH terms: Case Reports

Background: A bilateral diaphragmatic rupture is a rare event that occurs in cases of blunt thoracic-abdominal trauma. Case Presentation: We report the case of a 56-year-old female patient with pelvic fracture and second-stage bilateral rupture of the diaphragm due to a car accident. After a chest and abdominal contrast-enhanced computed tomography (CT) scan, the patient underwent emergency suturing of the left hemidiaphragm. On postoperative day (POD) 4, a CT scan performed due to the sudden onset of dyspnea revealed rupture of the right hemidiaphragm, which was not detected on the preoperative CT scan. On POD 9, the right hemidiaphragm was repaired with mesh during a right thoracotomy. The patient recovered 14 days after surgery. However, the postoperative course was complicated by an asymptomatic COVID-19 infection that significantly delayed her discharge from the hospital. Conclusions: Difficulties in preoperative diagnosis and treatment, together with the lack of data in the literature, make this type of trauma a challenge for all acute care and general surgeons.
Eosinophilic pneumonia associated with daptomycin: a case report and a review of the literature
Authors: Andreas S Kalogeropoulos, Sotirios Tsiodras, Dionysios Loverdos, Panagiotis Fanourgiakis, Athanasios Skoutelis
Journal: J Med Case Rep (2011)

Introduction:
Although several studies did not demonstrate that daptomycin may cause significantly higher rates of pulmonary adverse effects when compared with vancomycin or penicillinase-resistant penicillins, there have been a few case reports of severe pulmonary complications associated with daptomycin administration.
Case presentation:
A rare case of eosinophilic pneumonia occurring 10 days after daptomycin administration in a 78-year-old Caucasian man with possible infectious endocarditis is described. He developed new onset fever, up to 38.5°C, with bilateral pulmonary crackles on physical examination and with no signs of severe respiratory failure. A chest computed tomography-scan showed bilateral nodular consolidations with air bronchograms and pleural effusions. Immediate discontinuation of daptomycin was followed by vigorous improvement of clinical signs and symptoms with progressive resolution of pulmonary consolidations a month later.
Conclusion:
Physicians should be aware of this rare but serious complication during daptomycin treatment, and prompt discontinuation of the offending agent, with or without additional supportive treatment, must occur immediately.
Giant Liver Hemangiomas: A Plea for Early Surgical Referral and Resection
Authors: Alvin Chang, Brianna Ruch, Aamir Khan, Marlon Levy, Amit Sharma
Journal: Case Rep Surg (2020)
MeSH terms: Case Reports

Hepatic hemangiomas are the most common benign hepatic tumor. Current guidelines recommend surveillance imaging and reserving surgical intervention for symptomatic patients with giant liver hemangiomas (>5 cm). We present the case of a patient with a rapidly enlarging giant hepatic hemangioma initially managed by surveillance. During her observation period, she developed weight loss, constipation, and pancytopenia concerning for Kasabach-Merritt Syndrome. Resection of the hemangioma was complicated by its large size (28.0 × 18.0 × 11.4 cm). Patients with rapidly growing giant liver hemangiomas, even when asymptomatic, should be promptly referred to specialized surgical centers for evaluation and management.