OpenMed/multicare-articles huggingface dataset:
Case report: Case series of isolated acute pericarditis after SARS-CoV-2 vaccinations
Authors: Marco M Ochs, Markus Haass, Saskia Hagstotz, Sorin Giusca, Grigorios Korosoglou
Journal: Front Cardiovasc Med (2022)
Keywords: sars-cov-2 vaccination, t1 and t2 mapping, acute isolated pericarditis, cardiac troponins, isolated pericarditis after sars-cov-2 vaccination, late gadolinium enhancement
MeSH terms: Case Reports

During the worldwide ongoing immunization campaign against SARS-CoV-2, growing data on very rare but potentially harmful side effects of such vaccines arise since approval trials have not been adequately powered to detect those events. Besides the already reported vaccine-related myocarditis, which primarily occurs in young male individuals, our attention was recently drawn to a series of older male and female patients, who were referred to our institutions with isolated acute pericarditis without myocardial damage, shortly after SARS-CoV-2 vaccination. We describe a series of five adult patients presenting with chest pain, shortness of breath and isolated pericarditis with and without pericardial effusion after SARS-CoV-2 vaccination. All patients underwent echocardiography and cardiac magnetic resonance, and the corresponding findings, including late gadolinium enhancement (LGE) and T1 and T2 mapping are reported herein. To our knowledge, such cases have not been systematically reported in the current literature so far.
COVID-19 and Skin Manifestations: An Overview of Case Reports/Case Series and Meta-Analysis of Prevalence Studies
Authors: Fatemeh Sameni, Bahareh Hajikhani, Somayeh Yaslianifard, Mehdi Goudarzi, Parviz Owlia, Mohammad Javad Nasiri, Shervin Shokouhi, Mahmood Bakhtiyari, Masoud Dadashi
Journal: Front Med (Lausanne) (2020)
Keywords: 2019-ncov, covid-19, coronavirus, meta-analysis, skin manifestations
MeSH terms: Systematic Review

Background and Aim: Since the onset of the 2019-nCoV disease (COVID-19), many skin manifestations have been reported in COVID-19 patients. This study aims to provide a systematic review and meta-analysis of various skin manifestations among patients with COVID-19 through case reports/case series and prevalence studies. Methods: A systematic literature search strategy was conducted by reviewing original research articles published in Medline, Web of Science, and Embase databases in 2020. Statistical analysis was performed using STATA software, version 14.0 (Stata Corporation, College Station, Texas, USA) to report the global prevalence of skin manifestations among patients with COVID-19. Results: Forty-three studies (35 articles were case reports/case series, and 8 articles were prevalence studies) were included in our study. A meta-analysis of prevalence studies showed that skin manifestations among patients with COVID-19 were reported in four countries (China, Thailand, France, and Italy), with an overall prevalence of 1.0% [(95% CI) 0.1-1.9] among 2,621 patients. Evaluation of the results of the case reports/case series revealed that, out of 54 patients with COVID-19, 48 patients (88.8%) showed skin manifestations. Erythematous rash (59.1%) and urticaria (14.8%) were the most common skin manifestation reported in studied patients. Conclusion: Infection with 2019-nCoV may lead to skin manifestations with various clinical symptoms. These clinical features combined with clinical symptoms of COVID-19 may aid in the timely diagnosis of patients with COVID-19.
Surgical Treatment of a Patient with a Solitary Thyroid Metastasis from Primary Sigmoid Adenocarcinoma: A Case Report and Literature Review
Authors: Kohei Yamahara, Toshiaki Moriki, Yuki Katsura, Kana Lee, Satoshi Ikegami
Journal: Case Rep Otolaryngol (2019)
MeSH terms: Case Reports

Malignant metastases to the thyroid are rare and even rarer from colorectal cancer (CRC). Most cases of CRC metastasis to the thyroid involve metastases to other organs as well, particularly the liver and/or lung. There are only three reports of CRC metastasizing to the thyroid without involvement of another site. Patients with solitary thyroid metastasis from CRC have a poor prognosis after surgery, whereas resection is beneficial in their counterparts with a solitary liver or lung metastasis. This difference could be the result of delayed diagnosis of thyroid metastasis in patients with CRC, given that postoperative follow-up examination of the thyroid is not routinely performed. Here we describe a patient who was found to have a solitary metastasis of sigmoid cancer to the thyroid on postoperative imaging and has had prolonged disease-free survival after thyroidectomy. Our experience suggests that a low threshold of suspicion is crucial for timely diagnosis of thyroid metastasis from CRC and that resection can improve disease-free survival.
The Role of Heart Team Approach in Penetrating Cardiac Trauma: Case Report and Review of the Literature
Authors: Marzia Cottini, Amedeo Pergolini, Federico Ranocchi, Francesco Musumeci
Journal: Braz J Cardiovasc Surg (2018)
MeSH terms: Cardiac Tamponade / etiology, Heart Injuries / etiology, Wounds, Penetrating / complications, Case Reports, Review, Adult, Cardiac Tamponade / surgery, Coronary Angiography, Echocardiography, Heart Injuries / surgery, Humans, Male, Patient Care Team, Self-Injurious Behavior / complications, Wounds, Penetrating / surgery

Penetrating cardiac trauma has been increasing in clinical experience and is joined to important morbidity and mortality. A case of a 38-year-old female with history of postpartum depression was reported, admitted to our department for cardiac tamponade due to penetrating self-inflicted multiple stab wound of the chest complicated by rupture of anterior left ventricular wall and traumatic ventricular septal defect. Following the unstable hemodynamic instability, a combined therapeutic strategy was chosen: surgery and transcatheter implantation to correct free wall ventricle damage and traumatic ventricular septal defect, respectively.
Unstimulated Serum Thyroglobulin Levels after Thyroidectomy and Radioiodine Therapy for Intermediate-Risk Thyroid Cancer Are Not Always a Reliable Marker of Lymph Node Recurrence: Case Report and a Lesson for Clinicians
Authors: Luca Foppiani, Simona Sola, Manlio Cabria, Gianluca Bottoni, Arnoldo Piccardo
Journal: Case Rep Endocrinol (2020)
MeSH terms: Case Reports

Over 50% of patients with papillary thyroid carcinoma (PTC) have cervical lymph-node metastasis on diagnosis, and up to 30% show nodal recurrence after surgery plus radioactive iodine (131I) (RAI) therapy. The combination of ultrasonography (US) and fine-needle aspiration cytology (FNAC) and the measurement of thyroglobulin (Tg) in washout fluid are cornerstones in the diagnosis of nodal metastasis. In the absence of anti-Tg antibodies, unstimulated serum thyroglobulin (Tg) levels are generally a reliable marker of recurrent disease, and 18F-FDG positron emission tomography (PET)/computed tomography (CT) plays an important role in the imaging work-up. We report the case of a 65-year-old man evaluated for a large multinodular goitre which caused compressive symptoms; the dominant nodule in the left lobe presented suspicious features on US. Thyroid function showed subclinical hypothyroidism, calcitonin was normal, serum thyroglobulin levels were low, and anti-thyroid antibodies were absent. The prevalent left nodule showed an intense uptake on 18F-FDG PET/CT but proved benign at FNAC. On the basis of the suspicious clinical and imaging features, total thyroidectomy was performed. Histology revealed a tall-cell variant of PTC with scattered expression of Tg and diffuse high expression of cytokeratin (CK) 19; RAI therapy was performed. Within 6 years of surgery, left laterocervical lymph-node recurrence was twice detected (first at levels II and III, then at levels IV and VI) by US and 18F-FDG-PET/CT and was confirmed by FNAC. Tg levels in the washout fluid proved clearly diagnostic of metastasis only in the second, larger, recurrence, whereas serum Tg levels (in the absence of anti-Tg antibodies) always remained undetectable on L-thyroxine therapy. Surgery was performed on both recurrences, and histology confirmed lymph-node metastasis of PTC. Immunohistochemical expression of Tg and CK 19 was similar to that of the primary tumour. No further relapses have occurred to date. Posttherapy (surgery and RAI) unstimulated serum Tg levels may not be a reliable marker of nodal recurrence in patients with differentiated thyroid cancer (DTC) that produces low amounts of Tg.
A pediatric case developing critical abdominal distension caused by a combination of humidified high-flow nasal cannula oxygen therapy and nasal airway
Authors: Satoki Inoue, Yumiko Tamaki, Shota Sonobe, Junji Egawa, Masahiko Kawaguchi
Journal: JA Clin Rep (2018)
Keywords: abdominal distention, complication, high-flow nasal cannula, humidified, nasal airway, pediatric patient

Background:
We describe a pediatric patient who suffered from critical abdominal distention caused by a combination of humidified, high-flow nasal cannula (HHFNC) oxygen therapy and nasal airway.
Case presentation:
A 21-month-old boy with a history of chronic lung disease was admitted to the intensive care unit (ICU). Immediately after admission, his airway was established using a tracheal tube and mechanical ventilation was started. Five days after the commencement of mechanical ventilation, finally, his trachea was extubated. Immediately after extubation, HHFNC therapy at 20 L/min with an FiO2 of 0.35 was applied. However, severe stridor was observed, then a nasal airway was placed in the left nostril. However, he became restless. Critical abdominal distention was observed. A subsequent chest X-ray revealed that the nasal airway was placed too deeply, and the gastrointestinal air was severely accumulated. Immediately, the nasal airway was removed, and HHFNC flow was reduced to 10 L/min. Frequent suctioning and continuous gastric drainage were required, which achieved gradual improvement of respiratory condition.
Conclusions:
We need to recognize that HHFNC therapy is one of the positive pressure ventilation system. Therefore, HHFNC therapy might cause the similar adverse events to noninvasive pressure ventilation.
Fire acupuncture for anti-LGI1 antibody autoimmune encephalitis: a case report
Authors: Yu Liu, Yu Gong, Xiao-Li Wu, Xiao-Min Hao, Ji-Peng Liu, Yin-Yin Li, Ke-Zhen Yang, Xin-Yu Gao, Jing Zhang, Lin Zhang, Xu-Dong Zhang, Jun Wang, Qing-Guo Liu
Journal: Front Neurosci (2023)
Keywords: autoimmune diseases, cognitive dysfunction, fire acupuncture, glucocorticoids, inflammation
MeSH terms: Case Reports

Autoimmune encephalitis, a class of encephalitis, is clinically characterized by multifocal or diffuse brain injury, including aberrant mental behavior, convulsions, and near-event memory impairment. In this article, we describe a female patient with autoimmune encephalitis who tested positive for leucine-rich glioma inactivated 1 (LGI1) antibodies and had hippocampal inflammatory edema in the lesion area. During the first 3 months of her illness, the patient primarily experienced memory loss, the onset of rigid twitching in her extremities that lasted for 1 min while in remission, and incontinence. After gamma globulin administration, methylprednisolone shock, and other symptomatic therapies during hospitalization, the patient's psychiatric symptoms and seizures improved considerably; however, she did not fully recover her memory. After receiving fire acupuncture for 6 months, the patient's understanding, orientation, and calculation skills improved considerably. Her memory and mental state were also improved at the follow-up visit. In this case, the use of fire acupuncture for the treatment of autoimmune encephalitis resulted in favorable outcomes with important benefits for conditions affecting the central nervous system; however, more convincing data are required to support the effectiveness of this treatment method.
Oral haemangioma
Authors: Jaspreet Singh Gill, Sharanjeet Gill, Amit Bhardwaj, Harpreet Singh Grover
Journal: Case Rep Med (2012)
MeSH terms: Case Reports, Retracted Publication

Vascular anomalies comprise a widely heterogeneous group of tumours and malformations. Haemangioma is the most common benign tumour of vascular origin of the head and neck region. The possible sites of occurrence in oral cavity are lips, tongue, buccal mucosa, and palate. Despite its benign origin and behaviour, it is always of clinical importance to the dental profession and requires appropriate management. This case study reports a rare case of capillary haemangioma on the palatal gingiva in a 14-year-old female.
Transmigration of a retained surgical sponge: a case report
Authors: Tushar Patial, Namit Rathore, Angesh Thakur, Digvijay Thakur, Kanika Sharma
Journal: Patient Saf Surg (2018)
Keywords: case report, gossypiboma, retained surgical items, retained surgical sponge, textiloma
MeSH terms: Case Reports

Background:
A retained surgical sponge remains a dreaded complication of modern surgery. Despite the increasing focus on patient safety instances of "a sponge being left in the abdomen", are all too common in popular media. In this article we report the rare phenomenon of transmigration of a retained surgical sponge in a patient who underwent laparoscopic sterilization.
Case presentation:
A 30-year-old female presented with progressive abdominal pain for about one month and vomiting with obstipation for 2 days. The patient had undergone laparoscopic sterilization 7 years back and then underwent re-canalization one year back. She underwent an exploratory laparotomy for suspected adhesive small bowel obstruction. During surgery, an intra-luminal surgical sponge was recovered from the distal small bowel. The patient recovered and was discharged in good health.
Conclusion:
Despite numerous advances in terms of technology and the ever-growing emphasis on patient safety, the problem of a retained surgical sponge remains a dreaded potential complication. All clinicians and health care professionals should be aware of this entity and its various presentations.
Case report: Reproductive organ preservation and subsequent pregnancy for an infertility patient with lynch syndrome-associated synchronous endometrial cancer and colon cancer after treatment with a PD-1 checkpoint inhibitor
Authors: Di Cao, Yu Gao, Rong-Xin Zhang, Fu-Long Wang, Cong Li, Miao-Qing Wu, Yi-Fan Liu, Dan-Dan Li, Gong Chen
Journal: Front Immunol (2022)
Keywords: pd-1 inhibitor, case report, lynch syndrome, organ preservation, pregnancy
MeSH terms: Colonic Neoplasms / complications, Colorectal Neoplasms, Hereditary Nonpolyposis / complications, Endometrial Neoplasms / complications, Endometrial Neoplasms / pathology, Infertility, Case Reports, Adult, Female, Genitalia, Humans, Infant, Newborn, Male, Organ Preservation, Pregnancy, Programmed Cell Death 1 Receptor, Programmed Cell Death 1 Receptor

Currently, immune checkpoint inhibitors (ICIs) are the mainstay of treatment for Lynch syndrome patients. However, the tumor regression features in radiology and pathology are inconsistent for patients who are treated with ICIs, which sometimes confuses surgical decision-making. Here, we report a case in which a 36-year-old patient suffering from infertility was diagnosed with Lynch syndrome-associated synchronous endometrial cancer and colon cancer, and persistently enlarged left iliac paravascular lymph nodes were detected after receiving sintilimab treatment, a programmed cell death 1 (PD-1) receptor inhibitor. Fortunately, when she was about to undergo hysterectomy and bilateral salpingo-oophorectomy, intraoperative pathology examination did not reveal any cancer cells in these lymph nodes, and therefore, her reproductive organs were preserved. Later, the patient successfully conceived and gave birth to a healthy male neonate with no immune-related adverse events (irAEs) during an 11-month follow-up. This case indicates that surgeons should carefully inspect the imaging characteristics after immunotherapy and that organ preservation is possible even for patients who fail to achieve complete clinical regression, which is especially important for female patients of childbearing age.
Coronary artery to left ventricle fistula
Authors: Angel López-Candales, Vivek Kumar
Journal: Cardiovasc Ultrasound (2005)
MeSH terms: Coronary Artery Disease / diagnostic imaging, Coronary Artery Disease / etiology, Fistula / diagnostic imaging, Fistula / etiology, Heart Valve Prosthesis Implantation / adverse effects, Ventricular Dysfunction, Left / diagnostic imaging, Ventricular Dysfunction, Left / etiology, Case Reports, Aged, Female, Humans, Ultrasonography

Background:
Coronary cameral fistulas are an uncommon entity, the etiology of which may be congenital or traumatic. They involve abnormal termination of a coronary artery, usually the right coronary, into a cardiac chamber, usually the right ventricle.
Case presentation:
We describe a case of female patient with severe aortic stenosis and interventricular septal hypertrophy that underwent bioprosthetic aortic valve replacement with concomitant septal myectomy. On subsequent follow-up an abnormal flow traversing the septum into the left ventricle was identified and Doppler interrogation demonstrated a continuous flow, with a predominantly diastolic component, consistent with coronary arterial flow.
Conclusion:
The literature on coronary cameral fistulas is reviewed and the etiology of the diagnostic findings discussed. In our patient, a coronary artery to left ventricle fistula was the most likely explanation secondary to trauma to the septal perforator artery during myectomy. Since the patient was asymptomatic at the time of diagnosis no intervention was recommended and has done well on follow-up.
IgG4-Related Ophthalmic Disease Presenting as Meningitis and Panuveitis
Authors: Maria A Mavrommatis, Sarah A Avila, Richard France
Journal: Case Rep Ophthalmol Med (2019)
MeSH terms: Case Reports

Purpose:
We report an uncommon case of immunoglobulin gamma 4-related ophthalmic disease (IgG4-ROD) presenting as meningitis and panuveitis.
Observations:
A 35-year-old male with no prior ophthalmic history presented with headaches, altered mental status, and fever of unknown origin. A lumbar puncture (LP) revealed an elevated white count with lymphocytic predominance, confirming a suspected meningitis. After an extensive work-up, he was discharged on oral acyclovir to cover for presumed aseptic meningitis. The patient initially improved, however, bilateral eye pain, redness, and photophobia 2 weeks after discharge prompted his first visit to the ophthalmology clinic. Exam at that time was consistent with bilateral anterior uveitis for which he was given topical prednisolone and cyclopentolate. In addition to the preceding work-up, quantitative immunoglobulin serology including IgG4 levels was added. At follow-up, he was found to have increased ocular inflammation with vitreitis, nerve head edema, and subclinical macular thickening. Visual acuity (VA) had decreased in both eyes. Serology titers for IgG had resulted in a significant elevation in IgG subclass 4 (IgG4). Optical coherence tomography (OCT) and fundus fluorescein angiography (FFA) confirmed posterior retinal involvement. The patient was diagnosed with presumed bilateral panuveitis secondary to IgG4-ROD.
Conclusions and importance:
IgG4-RD can be a serious condition that requires careful consideration and intuition to diagnose. This report serves to encourage ophthalmologists to consider IgG4-ROD in cases of idiopathic systemic inflammation with ophthalmic involvement.
Variations in the origin and course of the suprascapular artery: case report and literature review
Authors: Rajani Singh
Journal: J Vasc Bras (2018)
Keywords: axillary artery, suprascapular artery, suprascapular notch, transverse scapular ligament
MeSH terms: Case Reports

The suprascapular artery is normally a branch of the thyrocervical trunk of the subclavian artery. During dissection of the left upper limb of a female cadaver, aged 70 years and fixed in 10% formalin solution, the suprascapular artery was observed aberrantly arising from the first part of the axillary artery. Later, it coursed obliquely behind the clavicle bone and brachial plexus to reach the suprascapular notch, where it was accompanied by the suprascapular nerve. Then, both suprascapular nerve and artery anomalously traversed beneath the transverse scapular ligament. It then irrigated the supraspinatus muscles and took part in the anastomosis around the scapula. On the contralateral side there was no abnormality. Variations in the origin and course of suprascapular artery are of immense value to orthopedic and vascular surgeons, angiographists, and anatomists.
Tuberculosis of the Thyroid Gland Presented as a Rapid Enlargement of a Preexisting Goiter
Authors: Ibtissem Oueslati, Imen Sakka, Olfa Ismail, Ines Akrout, Adel Marghli, Melika Chihaoui
Journal: Case Rep Endocrinol (2018)
MeSH terms: Case Reports

Thyroid involvement with tuberculosis is an uncommon condition even in endemic countries. As its clinical presentation is not specific, diagnosis is often difficult and requires histopathological confirmation. Herein we report an observation of secondary tuberculosis of the thyroid gland in a woman with a type 2 diabetes mellitus and a primary hypothyroidism. She presented with a rapid enlargement of a preexisting goiter without compressive symptoms. The imaging exams showed a voluminous plunging multinodular thyroid gland and multiple bilateral lung nodules. Malignancy was suspected and the patient underwent a total thyroidectomy and a lung biopsy. Histopathological examination revealed multiple tuberculous foci involving both the thyroid gland and the lungs.
Successful treatment in a case of Propionibacterium acnes-associated sarcoidosis with clarithromycin administration: a case report
Authors: Nobuo Takemori, Masaya Nakamura, Masaru Kojima, Yoshinobu Eishi
Journal: J Med Case Rep (2014)

Introduction:
Sarcoidosis is recognized as a multiorgan disorder characterized by the presence of non-caseating granulomas in the involved tissues. It has been suggested that sarcoidosis might be due to the exposure to infectious or non-infectious agents in genetically susceptible individuals. In particular, Propionibacterium acnes and Mycobacterium tuberculosis have been considered causative microorganisms. We report a case of P. acnes-associated sarcoidosis in which a drastic improvement was achieved with clarithromycin administration. A possible mechanism of clarithromycin action is discussed.
Case presentation:
A 78-year-old Japanese-Mongoloid woman with P. acnes-associated sarcoidosis presented with a persisting fever, joint pains and generalized lymph node swelling. The diagnosis of sarcoidosis was confirmed by pathological and immunohistochemical studies of a biopsied lymph node. In this case, an oral administration of clarithromycin was applied. Soon after the initiation of this treatment her symptoms as well as lymph node swelling disappeared. The clarithromycin treatment was discontinued 3.5 months after its initiation. She is currently in good condition. The pathological analysis of her lymph node, which was obtained during the clarithromycin treatment, suggested an apoptosis-inducing effect of clarithromycin on the sarcoid granulomas.
Conclusions:
Clarithromycin was found to be effective for treating sarcoidosis and seems to have important pharmacological effects such as immunosuppression, immunomodulation and induction of apoptosis in addition to its antimicrobial role. In this case, apoptosis in the sarcoid granulomas induced by clarithromycin administration might have resulted in satisfactory improvement.