OpenMed/multicare-articles huggingface dataset:
Odontogenic Myxoma in Children: A Case Report and Literature Review
Authors: Mariana Dalbo Contrera Toro, Icléia Siqueira Barreto, Eliane Maria Ingrid Amstalden, Carlos Takahiro Chone, Leopoldo Nizam Pfeilsticker
Journal: Case Rep Oncol Med (2016)

Benign odontogenic lesions are rare entities but are very important due to their locally aggressive nature. Odontogenic myxoma is even rarer in children than in adults. There is no evidence in the literature in regard to the best treatment approach, in terms of conservative or aggressive surgery, for this type of tumor. This paper reports a case of odontogenic myxoma in a child treated with a compromised approach through bone osteotomies and a review of the literature about this disease, especially in pediatric patients.
Evaluation and Management of Symptomatic Vasospasm following Endoscopic Endonasal Resection of Pediatric Adamantinomatous Craniopharyngioma
Authors: Dustin Hansen, Joaquin Hidalgo, Alan Cohen, Debraj Mukherjee, Susanna Scafidi
Journal: Case Rep Pediatr (2020)
MeSH terms: Case Reports

Background:
Cerebral vasospasm is a well-described pathology following subarachnoid hemorrhage and trauma in children; however, very few cases have been published following craniopharyngioma resection in children. Those that were published were associated with significant morbidity or mortality at hospital discharge. Case Summary. Here, we report the challenging clinical course of a pediatric patient who developed delayed cerebral vasospasm following craniopharyngioma resection. It was first noted on postoperative day 13. The patient was managed with induced hypertension, hypervolemia, and intra-arterial vasodilator therapy (nicardipine). This patient made a full recovery without new focal deficits at hospital discharge.
Conclusion:
In contrast to previously reported similar pediatric cases, this patient with cerebral vasospasm after craniopharyngioma resection made a full recovery without new focal neurologic deficits. To our knowledge, this is the first occurrence of a patient with this clinical course.
A Case Study of Multiple Maintenance Efficacy in Gynaecological Surgery Assessed by Deep Learning
Authors: Yanmei Zheng, Qi Yuan
Journal: Comput Math Methods Med (2022)
MeSH terms: Deep Learning, Anxiety / prevention & control, Female, Gynecologic Surgical Procedures, Humans

Deep learning is a new learning concept and a highly effective way of learning, which is still being explored in the field of nursing education. This paper analyses the effectiveness of interventions in perioperative gynaecological care using humanised care in the operating theatre and the impact of this model of care on patients' psychological well-being and sleep quality. A deep learning-based vision robot was designed to provide higher quality of care for our human care and simplify our approach to gynaecological surgery. The anxiety and depression scores of the two groups were significantly improved after and before care, and the scores of the observation group were lower than those of the control group, with a statistically significant difference (P < 0.05). The humanised care for gynaecological surgery patients in the perioperative period is more conducive to the improvement of their negative emotions and at the same time can improve the sleep quality of patients, so it can be further promoted.
Large hemorrhagic pericardial effusion with cardiac tamponade in a 16-year-old adolescent in an endemic area of tuberculosis: a case report
Authors: Clovis Nkoke, Christelle Makoge, Denis Tewafeu, Cyrille Nkouonlack, Charifa Njoya, Ines Nepetsoun, Engelbert Bain Luchuo, Ahmadou Musa Jingi
Journal: Pan Afr Med J (2021)
Keywords: pericardial effusion, cardiac tamponade, case report, tuberculosis
MeSH terms: Cardiac Tamponade / diagnosis, Cardiac Tamponade / epidemiology, Cardiac Tamponade / etiology, Pericardial Effusion / epidemiology, Pericardial Effusion / etiology, Tuberculosis / complications, Tuberculosis / diagnosis, Tuberculosis / drug therapy, Case Reports, Adolescent, Cameroon / epidemiology, Humans, Male, Pericardiocentesis

Pericardial effusion complicated by cardiac tamponade is a medical emergency. Large pericardial effusion and tamponade are rare in childhood. Tuberculosis remains a major cause of pericardial effusion in endemic areas. A 16-year-old adolescent with no significant past history was admitted to the medical unit of the Buea Regional hospital in the South West region of Cameroon for heart failure after presenting with abdominal distension, shortness of breath and fever of two weeks duration. Echocardiographic study during admission revealed a large pericardial effusion (27mm in thickness) with echocardiographic signs of tamponade. Echocardiographic guided pericardiocentesis was performed through a sub-xiphoid route and about 500 cc of heavily stained blood fluid that was not coagulating was drained. Pericardial fluid analysis for acid fast bacilli was negative. There was no evidence of malignancy. A strong suspicion of tuberculosis was made and he was started on anti-tuberculosis medications for presumptive hemorrhagic tuberculous pericarditis. Patient was asymptomatic during follow up and repeat echocardiographic examinations showed no re-accumulation of pericardial fluid. Tuberculosis should be considered as the etiology of pericardial effusion in endemic areas although the identification of mycobacterium is challenging in these settings.
Case report: Successful allogeneic stem cell transplantation in a child with novel GATA2 defect associated B-cell acute lymphoblastic leukemia
Authors: Edyta Heropolitańska-Pliszka, Barbara Piątosa, Anna Szmydki-Baran, Karolina Kuczborska, Karolina Miarka-Walczyk, Agata Pastorczak, Wojciech Młynarski, Łukasz Sędek, Tomasz Szczepański, Marek Ussowicz
Journal: Front Immunol (2022)
Keywords: gata2, acute lymphoblastic leukemia, hematopoietic stem cell transplantation, immunodeficiency, treosulfan
MeSH terms: Graft vs Host Disease / etiology, Hematopoietic Stem Cell Transplantation / adverse effects, Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy, Case Reports, Research Support, Non-U.S. Gov't, Adult, Child, Child, Preschool, Female, GATA2 Transcription Factor / genetics, Humans, Transplantation Conditioning / methods, Young Adult, GATA2 Transcription Factor, GATA2 protein, human

GATA-binding protein 2 (GATA2) is a transcription factor responsible for the regulation of blood cell proliferation, differentiation, and maintenance in hematopoietic stem cells. Here, we describe successful bone marrow transplantation in a carrier of a novel GATA2 pathogenic variant who was diagnosed with immunodeficiency a few years after completion of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) treatment. At the age of 4 years, the patient was diagnosed with and treated for BCP-ALL. Antileukemic therapy was complicated by pulmonary cryptococcosis. Two years after completion of the maintenance therapy, the child was consulted by an immunologist because of recurrent respiratory tract infections and an episode of sepsis. Flow cytometry revealed deep monocytopenia, lymphopenia, absence of B lymphocytes, considerably reduced NK cells, poor thymic T lymphocyte production, minor defects in T cell maturation, and absence of TCRγδ+ T cells. The presence of the likely pathogenic, heterozygous missense variant within exon 5 of GATA2 (NM_032638.5: c.1047T>G, Cys349Trp) was identified in the proband and confirmed in the father of the patient, who underwent allogeneic hematopoietic stem cell transplantation (HSCT) from a matched unrelated donor due to myelodysplastic syndrome with excess blasts at the age of 22 years. An allogeneic hematopoietic stem cell transplantation with a reduced toxicity conditioning protocol was performed using a matched sibling donor. Pre-transplant conditioning included fludarabine (5 × 30 mg/m2), treosulfan (3 × 14 g/m2), and thiotepa (10 mg/kg). Complete donor chimerism was achieved on post-transplant day 17. During the 12 months of the posttransplant observation period, she remained free from symptoms of acute or chronic graft-versus-host disease, and immunosuppressive treatment was therefore stopped. This is the second reported case of BCP-ALL in a patient with GATA2 deficiency, and the first successfully treated with a reduced-toxicity conditioning HSCT protocol. The co-occurrence of lymphoid malignancies and primary immunodeficiencies points to the role of genetic counseling and family screening for possible cancer predisposition syndromes prior to the selection of related HSCT donors.
Successful propranolol treatment of a large size infantile hemangioma of the face causing recurrent bleeding and visual field disruption
Authors: Muhammad Saaiq, Bushra Ashraf, Saad Siddiqui, Shehzad Ahmad, Muhammad Salman Zaib
Journal: World J Plast Surg (2015)
Keywords: bleeding, infantile hemangioma, propranolol, visual field
MeSH terms: Case Reports

A 29 days old Pakistani female infant was presented to our outpatient department with two weeks history of a rapidly progressing large size facial hemangioma involving most of the right cheek and right eyelids. The infant was unable to open the right eye. There was also a small hemangioma on the right second toe. Additionally, three similar lesions were found on the right side of the palate and adjoining buccogingival surfaces. The parents were particularly concerned about the explosive progression of the lesions, recurrent bleeding episodes from ulcerated areas of the cheek lesion and complete occlusion of the right eye. Following four weeks therapy with propranolol in a dose of 2 mg/kg/day, the hemangiomas rapidly regressed, the bleeding episodes ceased and the infant started opening the eye.
Characterization of Fungal Colonization of Indwelling Esophagostomy Tubes
Authors: Shelly J Olin, David A Bemis, John R Dunlap, Jacqueline C Whittemore
Journal: Case Rep Vet Med (2019)
MeSH terms: Case Reports

Fungal colonization of feeding tubes occurs rapidly in people, resulting in decreased structural integrity and complications such as luminal obstruction and tube failure. Esophagostomy tubes (E-tubes) are commonly used in dogs and cats for enteral support, but data are lacking regarding colonizing fungi and the impact of colonization on tube integrity. In this study, esophagostomy tubes were collected in lieu of disposal from dogs and cats undergoing feeding tube exchange. Fungi were isolated with culture and identified using morphological characteristics. Scanning electron microscopy was used to evaluate the surface characteristics of the tubes. Two silicone and one polyurethane E-tube were evaluated. Fungi associated with the normal microbiota, including Candida sp. and Penicillium sp., as well as environmental fungi were identified. This case series represents the first documentation of fungal colonization of silicone and polyurethane E-tubes in dogs and cats. Additionally, this is the first report to document degenerative changes in a silicone E-tube.
Cutaneous absorption of Oleander: Fact or fiction
Authors: S Senthilkumaran, S Saravanakumar, P Thirumalaikolundusubramanian
Journal: J Emerg Trauma Shock (2009)
Keywords: oleander leaf extract, reversible cardiac conduction disorder, transcutaneous absorption
MeSH terms: Case Reports

Cardiac conduction disorders following oral ingestion of Oleander plant materials were documented earlier. Transcutaneous absorption of yellow oleander (Thevetia peruviana) leaf extract applied over non intact skin (raw wound) resulting in reversible cardiac conduction disorder observed in four healthy males who were free from any other systemic or electrolyte or metabolic disorders or exposure to pesticide or toxins is reported for the first time. Their hematological, biochemical, clinical, and echocardiogram status were within normal limits and free of any abnormalities. One among the four, presented for weakness and breathlessness (class II). He had bradycardia with Mobitz II block and hypotension without any other demonstrable localizing signs. The other three were identified in the community and without any symptoms. However, their ECG revealed bradycardia with Mobitz I block in two and complete heart block in the other. All of the four recovered well without any untoward events. Hence, it is suggested that physicians and practitioners have to elicit history and route of administration of unconventional therapy, whenever they are confronted with clinical challenges and during medical emergencies before embarking final decision.
Case Report: Anal canal duplication associated with anorectal stenosis-A rare presentation
Authors: Zhen Zheng, Dong Xiao, Junxiang Wang, Haozhong Xu, Jianxiong Mao, Xiuliang Wang
Journal: Front Pediatr (2022)
Keywords: alimentary tract duplication, anal canal duplication, case reports, congenital malformations, constipation, megacolon
MeSH terms: Case Reports

Anal canal duplication is a rare gastrointestinal malformation characterized by extra anal orifices at 6 o'clock in the lithotomy position. To date, there have been only 110 reported cases. The purpose of this study is to contribute two infant cases, one of which is associated with anorectal stenosis, which has never been described.
Lupus and NMOSD: The Blending of Humoral Autoimmunity
Authors: Maria Goretti S Ochi, Samantha C Shapiro, Esther Melamed
Journal: Case Rep Rheumatol (2020)
MeSH terms: Case Reports

Systemic lupus erythematous (SLE) is a chronic autoimmune disease that can target any organ of the body. It may coexist with other autoimmune neurologic conditions such as neuromyelitis optica spectrum disorder (NMOSD). NMOSD, previously known as Devic's disease, is an autoimmune inflammatory disorder of the central nervous system (CNS) that targets the spinal cord, optic nerves, and certain brain regions. Most current evidence suggests that NMOSD is best described as a CNS astrocytopathy. While these diseases share several immunosuppressive treatment options, timely diagnosis of NMOSD is critical as patients may benefit from treatment tailored specifically to NMOSD as opposed to SLE. Steroids, plasmapheresis, intravenous immunoglobulin, cyclophosphamide, azathioprine, mycophenolate mofetil, and rituximab are used to treat both SLE and NMOSD. However, there are several new therapies (inebilizumab, eculizumab, and satralizumab) recently approved specifically for use in NMOSD. In this case series, we report on three patients with coexisting SLE and NMOSD. We describe a 31-year-old woman who suffered an NMOSD flare after 11 years of clinical remission in the context of receiving an influenza vaccination; her SLE remained quiescent on hydroxychloroquine. Next, we describe a 52-year-old woman with emergence of neurologically devastating seropositive NMOSD in the setting of active treatment for SLE with intravenous cyclophosphamide, oral steroids, and hydroxychloroquine. Last, we describe a 48-year-old woman with emergence of seronegative NMOSD in the setting of SLE that was well-controlled on azathioprine and hydroxychloroquine. These cases illustrate the importance of accurate diagnosis and targeted treatment of NMOSD when coexisting with SLE.
Epidural Anesthesia for Cesarean Section in a Pregnant Woman with Marfan Syndrome and Dural Ectasia
Authors: Franco Pepe, Mariagrazia Stracquadanio, Francesco De Luca, Agata Privitera, Elisabetta Sanalitro, Puccio Scarpinati
Journal: Case Rep Obstet Gynecol (2017)
MeSH terms: Case Reports

Marfan syndrome (MFS) is a genetic disorder of connective tissue, characterized by variable clinical features and multisystem complications. The anesthetic management during delivery is debated. Regional anesthesia has been used with success during cesarean delivery, but in some MFS patients there is a probability of erratic and inadequate spread of intrathecal local anesthetics as a result of dural ectasia. In these cases, epidural anesthesia may be a particularly useful technique during cesarean delivery because it allows an adequate spread and action of local anesthetic with a controlled onset of anesthesia, analgesia, and sympathetic block and a low risk of perioperative complications. We report the perioperative management of a patient with MFS and dural ectasia who successfully underwent cesarean section using epidural technique anesthesia. The previous pregnancy of this woman ended with cesarean section with a failed spinal anesthesia that was converted to general anesthesia due to unknown dural ectasia at that time.
Antiretroviral Drug-Associated Oral Lichenoid Reaction in HIV Patient: A Case Report
Authors: Pratanporn Arirachakaran, Mattana Hanvanich, Piyanad Kuysakorn, Kobkan Thongprasom
Journal: Int J Dent (2010)
MeSH terms: Case Reports

Antiretroviral therapy has changed the course of HIV disease and improved quality of life in HIV patients. Incidence of an oral lichenoid drug reaction induced by zidovudine is not common. Once it occurs, it affects a patient's well being, in particular their oral functions. Here we report the first case of a 34-year-old Thai man with painful erosive lesions involving the lip and buccal mucosa. Treatment with topical fluocinolone acetonide 0.1% alleviated the patient's oral pain, but it was not until the subsequent withdrawal of zidovudine that the patient showed improvement and resolution of the lesions. Long-term follow-up was useful in the management of this patient, and no recurrence of the lesion was found during 21-month follow-up in this patient.
Pneumothorax and Atelectasis Appearing as a Non-Specific Opacity on a Supine Infant's Chest X-Ray
Authors: Thomas Saliba, Grammatina Boitisios
Journal: J Belg Soc Radiol (2023)
Keywords: pneumothorax, complication, esophageal atresia, neonatal, pediatric
MeSH terms: Case Reports

Teaching Point: Thoracic postoperative complications are difficult to diagnose on supine chest X-rays, with pneumothoraxes accompanied by underlying atelectasis presenting as non-specific opacities due to the superposition of the two entities having opposed radiographic characteristics, with one causing lucency and the other opacity.
De Novo Autoimmune Hepatitis after COVID-19 Infection in an Unvaccinated Patient
Authors: Francisco A Durazo, Kelly Kristbaum, James Miller, Kia Saeian, Motaz Selim, Johnny C Hong
Journal: Case Reports Hepatol (2022)
MeSH terms: Case Reports

Liver test abnormalities have been described during severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection causing coronavirus disease 2019. Most of them consist of elevation of the aminotransferases that resolve once the infection subsides. There are several reports of autoimmune hepatitis developing after vaccination against COVID-19 and one case of autoimmune hepatitis following COVID-19 infection. We present a patient that was not vaccinated against COVID-19 and developed resistant de novo autoimmune hepatitis following COVID-19 infection requiring aggressive immunosuppression.
Human infection caused by Leptospira fainei
Authors: Jean-Pierre Arzouni, Philippe Parola, Bernard La Scola, Danièle Postic, Philippe Brouqui, Didier Raoult
Journal: Emerg Infect Dis (2002)
MeSH terms: Leptospira / classification, Leptospira / isolation & purification, Leptospirosis / microbiology, Case Reports, Adult, Amoxicillin / therapeutic use, Antibodies, Bacterial / immunology, Blotting, Western, Electrophoresis, Gel, Pulsed-Field, Humans, Immunoglobulin G / immunology, Immunoglobulin M / immunology, Leptospira / genetics, Leptospirosis / drug therapy, Leptospirosis / immunology, Male, Penicillins / therapeutic use, Phylogeny, Polymerase Chain Reaction, Species Specificity, Antibodies, Bacterial, Immunoglobulin G, Immunoglobulin M, Penicillins, Amoxicillin

We report a human case of leptospirosis in which the spirochete was detected by dark-field microscopy examination of cerebrospinal fluid (CSF) and isolated from both CSF and blood. Leptospira fainei was identified by sequencing the 16S rDNA gene, which had been amplified by polymerase chain reaction. This case confirms the role of L. fainei as a human pathogen and extends its distribution to southern Europe.
Uterine artery pseudoaneurysm in the setting of delayed postpartum hemorrhage: successful treatment with emergency arterial embolization
Authors: Ankur M Sharma, Brent E Burbridge
Journal: Case Rep Radiol (2011)
MeSH terms: Case Reports

Postpartum hemorrhage is a major cause of maternal mortality. Though uncommon, uterine artery pseudoaneurysm can follow uterine dilatation and curettage (D + C) and needs to be considered in the differential diagnosis. This 30-year-old G1P1 woman presented with right upper quadrant pain and vaginal bleeding. She was afebrile but her white blood count was significantly increased (22.2 × 10(9) /L). One week prior, she had undergone a Cesarean delivery which was complicated by hemolysis, elevated liver enzymes, and low platelet count syndrome (HELLP), fetal dystocia, and chorioamnionitis. Uterine dilatation and curettage (D & C) and placement of a Bakri intrauterine balloon, performed for suspected retained products of conception, failed to control her postpartum bleeding. The patient wished to have a hysterectomy only as a last resort in order to preserve fertility. Emergency uterine artery angiography revealed a left uterine artery pseudoaneurysm and contrast extravasation. The patient was successfully treated with selective embolization. Computed tomography (CT) later revealed dehiscence of her uterine Cesarean section incision with an intra-abdominal fluid collection. This collection was drained. She also developed disseminated intravascular coagulopathy (DIC) syndrome as well as multiple pulmonary emboli which were both successfully treated. We discuss this unique case of uterine artery pseudoaneurysm with associated uterine dehiscence.
Wickerhamomyces anomalous: A Rare Cause of Fungemia Causing Febrile Neutropenia in Acute Lymphoblastic Leukemia
Authors: Vibha Mehta, Aroop Mohanty, Suneeta Meena, J S Rahul, Nath Uttam Kumar, Debranjani Chattopadhyay, Anamika Bakliwal, Ranjana Choudhary, Pratima Gupta
Journal: Case Rep Infect Dis (2020)
MeSH terms: Case Reports

Candida bloodstream infection is the major cause of increased morbidity and mortality (20-49%) in hospitalized patients in both paediatric and adult age groups. Due to the increase in the number of immunocompromised patients, other important species such as Trichosporon asahii and Debaryomyces hansenii are emerging. One such organism, Wickerhamomyces anomalous, previously known as Pichia anomala (teleomorph stages of several Candida species), is increasingly being reported as a cause of fungemia in neonatal intensive care units and is now increasingly being reported in a lot of immunosuppressive conditions such as interstitial lung disease, endocarditis, enteritis, corticosteroids, and chemotherapy uptake. Though this yeast is ubiquitous in nature, systemic infections from isolated cases and sporadic outbreaks with high mortality have been reported in ICUs, which emphasize the importance to consider this fungus within the diagnostic possibilities. Here, we report a case of catheter-related bloodstream infection (CRBSI) caused by W. anomalus in a leukemic immunosuppressed patient who was successfully treated by early detection and treatment of this emerging fungus.
Identification of Dietzia spp. from Cardiac Tissue by 16S rRNA PCR in a Patient with Culture-Negative Device-Associated Endocarditis: A Case Report and Review of the Literature
Authors: Praveen Sudhindra, Guiqing Wang, Robert B Nadelman
Journal: Case Rep Infect Dis (2016)
MeSH terms: Case Reports

The genus Dietzia was recently distinguished from other actinomycetes such as Rhodococcus. While these organisms are known to be distributed widely in the environment, over the past decade several novel species have been described and isolated from human clinical specimens. Here we describe the identification of Dietzia natronolimnaea/D. cercidiphylli by PCR amplification and sequencing of the 16S rRNA encoding gene from cardiac tissue in a patient with culture-negative device-associated endocarditis.