OpenMed/multicare-articles huggingface dataset:
Restoring Balance-A Woman's Expressions of Lived Experience of Everyday Life During a Period of Aging: A Case Study
Authors: Margaretha Norell Pejner, Staffan Karlsson
Journal: Inquiry (2023)
Keywords: aging, case study, everyday life, experience, loss of spouse
MeSH terms: Aging / psychology, Bereavement, Social Support / psychology, Case Reports, Research Support, Non-U.S. Gov't, Aged, Aged, 80 and over, Female, Hermeneutics, Humans, Narration, Widowhood / psychology

Bereaved older people face stressors from the changes in roles associated with the death of a spouse. To illustrate the lived experience of everyday life during a period of aging after a woman's loss of her spouse. One woman born in 1918 was followed between 74 and 80 years of age after her husband died. Data consisted of daily diary. The text from the diaries were analyzed with a phenomenological hermeneutical approach. Everyday life after becoming a widow is characterized by balancing between personal resources to manage everyday life and vulnerability. In health and social care, it is important to identify experiences of vulnerability because these are associated with poor health.
A Case of Progressive Ossifying Fibrodysplasia of Tracheobronchial Respiratory Muscles
Authors: Nouraly Habib, Anhum Konan, Tra Bi Zamble Olivier Didier
Journal: Case Rep Radiol (2019)
MeSH terms: Case Reports

The authors report a case of progressive ossifying myositis (POM) in a 13-year-old boy, revealed by dry cough and dyspnea. Conventional chest x-rays and whole-body CT showed extraskeletal ossification that seems to affect the left bronchial strain and trachea. This lesional topography, if established, not yet described to our knowledge, contrasts with the observations of all the authors, including Munchmeyer, for whom smooth muscles and muscles attached to the skeleton by a single end are spared by the heterotopic ossifications characteristic of the disease. Therefore, this observation raises the question of the ubiquity of muscle ossifications during POM.
Presentation of massive orbital hidrocystoma at birth: case report and review of the literature
Authors: Bahram Eshraghi, Mohammad-Ali Abtahi, Seyed Ali Sonbolastan, Zahra Kasaie, Seyed-Hossein Abtahi
Journal: Eye Vis (Lond) (2017)
Keywords: orbital hidrocystoma, pediatric orbital tumor, sudoriferous cyst
MeSH terms: Case Reports

Background:
Hidrocystoma, or sudoriferous cyst, is an eyelid tumor originating from apocrine or eccrine sweat glands. Its presence in the orbit is relatively rare.
Case presentation:
A full-term female child with severe right eye extrusion was referred to our department two hours after birth. We performed cyst aspiration under ultrasonic guidance; 15 cc straw-colored fluid was obtained and proptosis resolved significantly. Orbital magnetic resonance imaging (MRI) showed a large unilocular retrobulbar mass with hypo-intensity in T1 and hyper-intensity in T2. The case underwent further daily ocular assessment until day 5; when proptosis began to worsen again. On day 6, under general anesthesia, we performed aspiration and then the cyst was completely removed with an intact wall through a trans-conjunctival incision. The diameter of the aspirated cyst was about 4 cm. In pathologic consultation, a cystic cavity lined by a layer of sweat duct like epithelium with apical snouts consistent with the diagnosis of apocrine hidrocystoma was reported.
Conclusion:
To date, in the literature, six other cases of orbital hidrocystoma have been reported in childhood with protean clinical pictures; none of which presented at birth. Herein, we introduce the first case report at birth and also provide a review on the literature. Our report strongly argues against the well reputed theory of traumatic origin for orbital hidrocystoma; it has been postulated that this tumor may be the result of sweat gland cells implantation through the orbit. We thereby suggest the possible presence of choristomatous ectopic sweat gland cells in the orbit during embryogenesis.
Ankylosis of the hips and knees due to sickle cell disease
Authors: Saad Saleh Abdullah Al Elayan, Abdullah Al Hamdan
Journal: F1000Res (2012)

This is a case report of a 29-year-old Saudi male with sickle cell disease (SCD) with severe stiffness of his joints, mainly both knees and hips, secondary to complications of SCD. He was severely crippled: unable to sit, stand or walk, and was bedridden for 8 years when he was presented to us. Radiographs showed fusion of both knees and hips. There was no evidence of active osteomyelitis by Gallium scan. The patient's hemoglobin S decreased to levels below 30% by exchange transfusion. Bilateral total hip replacement, as well as unilateral total knee replacement, was carried out to improve his level of function. There is only one reported case of such severe and multiple joint complications in a single patient suffering from SCD. The increased life expectancy that medical advances have offered to the sickle-cell patients has led to the appearance of sickle-cell-related complications, which were previously only seen rarely. These complications were successfully managed and the patient was able to move and transfer using a wheel chair.
Pedicle internal limiting membrane flap technique for very large macular holes: a preliminary report
Authors: José Edísio da Silva Tavares Neto, Igor Neves Coelho, Rodrigo Jorge, David Leonardo Cruvinel Isaac, Marcos Pereira de Ávila
Journal: Int J Retina Vitreous (2020)
Keywords: inner limiting membrane, macula lutea, macular hole, retina, vitrectomy, vitreous

Background:
Conventional vitrectomy technique for macular hole surgery has a good outcome in small and medium macular holes, but for very large macular holes (minimum linear diameter higher than 700 μm) other techniques were developed aiming to achieve greater rates of closure and visual acuity gain. The purpose of this article is to report the anatomical and functional outcomes of four very large macular hole (MH) cases which have undergone vitrectomy with the pedicle internal limiting membrane (ILM) flap technique.
Methods:
This is a retrospective series of four patients with large MH who were treated with vitrectomy and the pedicle ILM flap technique. Comprehensive ophthalmologic evaluation was performed before surgery and included ETDRS best-corrected visual acuity (BCVA) and spectral domain optical coherence tomography (SD-OCT) for MH measures: height, minimum linear diameter (MLD) and external base diameter. The particular detail of this technique is related to ILM flap creation. During the peeling, the ILM was not removed completely from the retina but was left attached to the edges of the macular hole and subsequently trimmed with the vitrectomy probe using the scissors mode.
Results:
Four patients with very large MH underwent PPV and the pedicle ILM flap technique was used to pursue macular closure. Median preoperative BCVA was 20/400 (range: 20/320 to 20/400) and median postoperative BCVA was 20/200 (range: 20/320 to 20/200). Of the 4 cases reported, 3 obtained anatomical closure (75%), and also presented BCVA improvement after surgery, considering the last follow-up visit of each case. No additional procedures were performed in either case. One patient demonstrated no anatomic and functional improvement.
Conclusion:
The present study describes the first Brazilian case series of very large MH treated by the inverted pedicle ILM flap technique. This technique was associated with anatomic and visual improvement in most cases, and represents an alternative therapeutic approach for large macular holes.Trial Registration Project registered in Plataforma Brasil with CAAE number 30163520.0.0000.5440 and approved in ethics committee from Ribeirão Preto Medical School Clinics Hospital, University of São Paulo-Ribeirão Preto, São Paulo, Brazil (appreciation number 3.948.426 gave the approval).
Congenital Granular Cell Tumor: Case Report and Review
Authors: Preston Gardner, Arlene Rozzelle
Journal: Case Rep Pediatr (2018)
MeSH terms: Case Reports

Congenital granular cell tumors are infrequently occurring masses occurring on a neonate's gingiva/alveolus. These lesions are benign with no noted malignant transformation, and treatment of excision is based on its effect on the neonate's respiratory ability and/or nutritional intake. The purpose of this review is to discuss a case of a congenital granular cell tumor and its treatment and review of the literature including demographics, histopathology, and operative treatment.
Skin manifestations associated with mantle cell lymphoma: a case report
Authors: Avinash Kumar Singh, Gaurav Dixit, Sanjeev Sharma, Suman Kumar, Rajni Yadav, Narendra Agrawal, Pravas Mishra, Tulika Seth, C Sarkar, M Mahapatra, Renu Saxena
Journal: Mediterr J Hematol Infect Dis (2013)
MeSH terms: Case Reports

Mantle cell lymphoma (MCL) is a distinct non-Hodgkin's lymphoma type that commonly affects extra nodal sites. The most often affected sites are bone marrow, gastrointestinal tract and Waldeyer's ring, being the skin rarely involved. We report a case of 56 year-old man with MCL, exhibiting multiple large maculopapular skin rashes and skin ulcers. Histopathological examination had not shown direct infiltration by any atypical cells. He had significant improvement of skin lesions with combination chemotherapy and debridement. Awareness of skin manifestations of MCL is crucial for dermatologists and haematologists to establish the early diagnosis and timely administration of appropriate treatment.
The first case of benign multicystic mesothelioma presenting as a splenic mass
Authors: Antonio D'Antonio, Carlo Baldi, Maria Addesso, Carmine Napolitano
Journal: Ecancermedicalscience (2016)
Keywords: immunohistochemistry, multicystic mesothelioma, peritoneum, prognosis, spleen
MeSH terms: Case Reports

Multicystic mesothelioma (MM) is a relatively rare tumour arising in the pelvic peritoneum of the tuboovarian region of young woman. Exceptionally, MM occurs on the serosal surfaces of various organs including kidney, bladder, lymph nodes, and liver. We report here the first case of MM wherein a 58-year-old woman with a previous history of endometriosis of the right ovary presented with a large multicystic mass of the spleen. The diagnosis of MM was made on a surgical specimen after splenectomy. A histopathologic examination is always necessary for the diagnosis of MM which should be differentiated from other lesions particularly from cystic lymphangioma. At one year follow-up, the patient had no evidence of recurrence. Despite the high frequency of local recurrences, MM is a benign lesion and 'en bloc' surgical excision with prolonged follow-ups is the treatment of choice.
Asymptomatic primary fallopian tube cancer: an unusual cause of axillary lymphadenopathy
Authors: N A Healy, S O Hynes, J Bruzzi, S Curran, M O'Leary, K J Sweeney
Journal: Case Rep Obstet Gynecol (2011)
MeSH terms: Case Reports

Primary Fallopian tube malignancy is considered a rare disease and is often mistaken histologically and clinically for ovarian cancer. The etiology is poorly understood, and it typically presents at an advanced disease stage, as symptoms are often absent in the initial period. As a result, primary fallopian tube cancer is generally associated with a poor prognosis. We present the case of a 45-year-old female who presents with a 5-day history of left axillary swelling and a normal breast examination. Mammogram and biopsy of a lesion in the left breast revealed a fibroadenoma but no other abnormalities. Initial sampling of the axillary node was suspicious for a primary breast malignancy, but histology of the excised node refuted this. PET-CT showed an area of high uptake in the right pelvis, and a laparoscopy identified a tumor of the left fallopian tube which was subsequently excised and confirmed as a serous adenocarcinoma.
Abdominal Flap Necrosis and Wound Dehiscence following a Medical Tourist Tummy Tuck
Authors: Vladislav Pavlovich Zhitny, Noama Iftekhar, Peter Caravella, Jake Patrick Young, Barry Zide, Frank Stile
Journal: Case Rep Surg (2020)
MeSH terms: Case Reports

Abdominoplasty is a major surgical procedure met with high rates of patient satisfaction and improved self-image. While many patients are lured abroad due to discounted prices for such highly requested procedures, unfortunately, there are also associated complications. A 47-year-old woman presented due to abdominal scar dehiscence due to skin necrosis secondary to a discounted abdominoplasty in Mexico. The patient had been turned away by several local surgical centers for treatment of the necrosis. The patient underwent incision, drainage, and two debridements before her abdominal wound was eventually closed. Patient recovered well postoperatively with improved aesthetic result. With the rise of social media advertisements, more patients elect to receive plastic surgery abroad. Unfortunately, many of these practices are not accurately vetted and this can complicate the postoperative care especially upon return to the United States.
Computed tomographic colonography in the evaluation of a case of giant colonic diverticulum
Authors: Aldo Carnevale, Matteo Bassi, Zairo Ferrante, Roberto Rizzati, Giorgio Benea, Melchiore Giganti
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

The aim of this article was to present our experience with CT-colonography evaluation of a case of giant colonic diverticulum. Despite the high prevalence of diverticular disease in the Western world, giant colonic diverticula are rare entities, with fewer than 200 cases reported in literature.
Acute Psychosis as Main Manifestation of Central Pontine Myelinolysis
Authors: Mangala Gopal, Melvin Parasram, Harsh Patel, Chike Ilorah, Hrachya Nersesyan
Journal: Case Rep Neurol Med (2017)
MeSH terms: Case Reports

Central pontine myelinolysis (CPM) is an acute demyelinating neurological disorder affecting primarily the central pons and is frequently associated with rapid correction of hyponatremia. Common clinical manifestations of CPM include spastic quadriparesis, dysarthria, pseudobulbar palsy, and encephalopathy of various degrees; however, coma, "locked-in" syndrome, or death can occur in most severe cases. Rarely, CPM presents with neuropsychiatric manifestations, such as personality changes, acute psychosis, paranoia, hallucinations, or catatonia, typically associated with additional injury to the brain, described as extrapontine myelinolysis (EPM). We present a patient with primarily neuropsychiatric manifestations of CPM, in the absence of focal neurologic deficits or radiographic extrapontine involvement. A 51-year-old female without significant medical history presented with dizziness, frequent falls, diarrhea, generalized weakness, and weight loss. Physical examination showed no focal neurological deficits. Laboratory data showed severe hyponatremia, which was corrected rather rapidly. Subsequently, the patient developed symptoms of an acute psychotic illness. Initial brain magnetic resonance imaging (MRI) was unremarkable, although a repeat MRI two weeks later revealed changes compatible with CPM. This case demonstrates that acute psychosis might represent the main manifestation of CPM, especially in early stages of the disease, which should be taken into consideration when assessing patients with acute abnormalities of sodium metabolism.
Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease
Authors: Feng Li, Xiaomei Zhang, Yanting Guo, Yuandong Zhu, Yicun Wu, Yun Ling
Journal: Case Rep Hematol (2018)
MeSH terms: Case Reports

Multicentric Castleman disease (MCD) is a rare nonmalignant lymphoproliferative disorder presenting systemic symptoms such as fever, night sweats, fatigue, anemia, effusions, and multifocal lymphadenopathy. The etiology of MCD has not been clarified to date. The coexistence of MCD with chronic myelomonocytic leukemia (CMML) has been rarely reported. Although the pathogenesis remains unclear, this association probably reflects an incidental and fortuitous finding rather than the alteration of a common pluripotent stem cell precursor. Herein, we report on one case of MCD coexisting with CMML and elucidate the underlying mechanism of pathology in some aspects.
Metatarsal Shaft Fracture with Associated Metatarsophalangeal Joint Dislocation
Authors: Taranjit Singh Tung
Journal: Case Rep Orthop (2016)

Metatarsophalangeal joint dislocations of lesser toes are often seen in the setting of severe claw toes. Traumatic irreducible dislocations have been reported in rare cases following both low-energy and high-energy injuries to the forefoot. In this case report, I present a previously unreported association of a metatarsal shaft fracture with metatarsophalangeal joint dislocation of a lesser toe.
A Rodential Reckoning: A Case Report and Systematic Review of Streptobacillary Endocarditis
Authors: Ashwin Mahesh, Eduardo Messias Hirano Padrao, Ravneet Randhawa, Christi Oommen, Johanna Romo, Ramachandra Illindala, Henry Anyimadu
Journal: Autops Case Rep (2023)
Keywords: endocarditis, rat bite fever, spirillum minus, streptobacillus moniliformis
MeSH terms: Case Reports

Introduction:
Endocarditis is a rare, often fatal complication of rat bite fever caused by Streptobacillus moniliformis. Only 39 cases have been reported (including this case) as of 2022. We describe a case and aim to perform this entit's first systematic literature review.
Methods:
We performed a systematic review in CENTRAL, EMBASE, MEDLINE, SciELO, and LILACS. The terms used were terms used were (but not limited to) rat bite fever, Streptobacillus moniliformis, Spirillum minus, and endocarditis. We included all abstracts and articles with patients with echocardiographic or histologic-proven endocarditis. In case of discordance, a third reviewer was involved. Our protocol was submitted to PROSPERO (CRD42022334092). We also performed searches for studies on the reference list of included articles.
Results:
We retrieved 108 and included 36 abstracts and articles. A total of 39 patients (including our report) were identified. The mean age was 41.27, and 61.5% were males. The most common findings were fever, murmur, arthralgias, fatigue, splenomegaly, and rash. Underlying heart disease was present in 33%. Exposure to rats was noted in 71.8% of patients, with 56.4% recalling a rat bite. Anemia was seen in 57%, leukocytosis in 52%, and elevated inflammatory markers in 58% that had lab work performed. The mitral valve was most affected, followed by the aortic, tricuspid, and pulmonary valves. Surgical intervention was required in 14 (36%) cases. Of those, 10 required valve replacement. Death was reported in 36% of cases. Unfortunately, the literature available is limited to case series and reports.
Conclusion:
Our review allows clinicians to suspect better, diagnose, and manage Streptobacillary endocarditis.
Case report: Bilateral panuveitis resembling Vogt-Koyanagi-Harada disease after second dose of BNT162b2 mRNA COVID-19 vaccine
Authors: Tomohito Sato, Ryotaro Nihei, Daisuke Sora, Yoshiaki Nishio, Masaru Takeuchi
Journal: Front Immunol (2022)
Keywords: bnt162b2 vaccine, vogt-koyanagi-harada disease, covid-19 mrna vaccines, cytof, heat map, multiplex bead analysis, uveitis
MeSH terms: COVID-19, Panuveitis / diagnosis, Panuveitis / drug therapy, Panuveitis / etiology, Uveomeningoencephalitic Syndrome / diagnosis, Uveomeningoencephalitic Syndrome / drug therapy, Uveomeningoencephalitic Syndrome / etiology, Case Reports, Research Support, Non-U.S. Gov't, BNT162 Vaccine, CD8-Positive T-Lymphocytes, COVID-19 Vaccines / adverse effects, Cyclosporine / therapeutic use, Epitopes, HLA-DR4 Antigen, Humans, Male, Middle Aged, RNA, Messenger / therapeutic use, SARS-CoV-2, COVID-19 Vaccines, Epitopes, HLA-DR4 Antigen, RNA, Messenger, Cyclosporine, BNT162 Vaccine

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a serious pandemic. COVID-19 vaccination is urgent needed for limiting SARS-CoV-2 outbreaks by herd immunity. Simultaneously, post-marketing surveillance to assess vaccine safety is important, and collection of vaccine-related adverse events has been in progress. Vision-threatening ophthalmic adverse events of COVID-19 vaccines are rare but are a matter of concern. We report a 45-year-old Japanese male with positive for HLA-DR4/HLA-DRB1*0405, who developed bilateral panuveitis resembling Vogt-Koyanagi-Harada (VKH) disease after the second dose of Pfizer-BioNTech COVID-19 mRNA (BNT162b2) vaccine. Glucocorticosteroid (GC) therapy combined with cyclosporine A (CsA) readily improved the panuveitis. The immune profile at the time of onset was analyzed using CyTOF technology, which revealed activations of innate immunity mainly consisting of natural killer cells, and acquired immunity predominantly composed of B cells and CD8+ T cells. On the other hand, the immune profile in the remission phase was altered by GC therapy with CsA to a profile composed primarily of CD4+ cells, which was considerably similar to that of the healthy control before the vaccination. Our results indicate that BNT162b2 vaccine may trigger an accidental immune cross-reactivity to melanocyte epitopes in the choroid, resulting in the onset of panuveitis resembling VKH disease.
Postoperative keratitis due to Paecilomyces: a rare pediatric case
Authors: Ebru Toker, Nihan Ziyade, Serkan Atici, Kepenekli Kadayifçi Eda, Özden Türel, Demet Toprak, Merih Oray, Nilgün Cerikcioglu, Ahmet Soysal, Mustafa Bakir
Journal: Pan Afr Med J (2016)
Keywords: fungal infection, paecilomyces, voriconazole
MeSH terms: Antifungal Agents / therapeutic use, Eye Infections, Fungal / diagnosis, Keratitis / diagnosis, Paecilomyces / isolation & purification, Case Reports, Adolescent, Amphotericin B / therapeutic use, Cornea / microbiology, Eye Infections, Fungal / drug therapy, Eye Infections, Fungal / microbiology, Humans, Keratitis / drug therapy, Keratitis / microbiology, Male, Ophthalmologic Surgical Procedures / adverse effects, Postoperative Complications / diagnosis, Postoperative Complications / drug therapy, Postoperative Complications / microbiology, Antifungal Agents, Amphotericin B

Fungal infections like Paecilomyces keratitis have emerged in childhood recently. The diagnosis and treatment of Paecilomyces keratitis is difficult and the outcome is usually poor. Corneal culture should be performed on fungal media such as Sabouraud glucose neopeptone agar (SDA) as soon as possible for diagnosis. We report a rare case of Paecilomyces keratitis in an immunocompetent child, which was unresponsive to amphotericin B. The case was managed by a multidisciplinary approach involving the departments of ophthalmology, microbiology and pediatric infectious diseases. We want to draw attention once again that fungal keratitis caused by unusual agents are increasing. Physicians should consider fungal causes of keratitis, in patients with some predisposing factors like ocular surgery and prolonged use of topical corticosteroids.