OpenMed/multicare-articles huggingface dataset:
CO2 Laser Division of Neo-Vallecula Improves Dysphagia in the Postlaryngectomy Patient: A Case Series and Review of the Literature
Authors: Mohamad Z Saltagi, Chelsey A Wallace, Avinash V Mantravadi, Michael W Sim
Journal: Case Rep Otolaryngol (2020)
MeSH terms: Case Reports

Objectives:
To review the literature on neo-vallecula diagnosis and management and to report our findings regarding 3 patients who developed neo-vallecula in the context of free-flap pharyngeal reconstruction following total laryngectomy.
Methods:
This case series reports three patients who developed a neo-vallecula following a laryngectomy and free-flap pharyngeal reconstruction. All three patients were treated with a CO2 laser endoscopic procedure.
Results:
Neo-vallecula formation is thought to be related to tension on the neopharyngeal closure or closure technique following total laryngectomy. Diagnosis may be obtained with swallow studies, videofluoroscopy, or endoscopy. Treatment has included external excision and endoscopic procedures such as stapling, harmonic scalpel excision, and laser removal. We utilized an endoscopic approach entailing the use of a CO2 laser to divide the neo-vallecula, and all our patients reported improvement in their dysphagia.
Conclusions:
Treatment of an anterior neo-vallecula endoscopically using a CO2 laser is an effective way to treat dysphagia in patients following total laryngectomy with free-flap pharyngeal reconstruction.
BK Virus Encephalitis in HIV-Infected Patients: Case Report and Review
Authors: Luciana Antoniolli, Rafael Borges, Luciano Z Goldani
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

Encephalitis and meningitis due to BKPyV are unusual and emerging condition. Only a few cases of BKPyV encephalitis have been reported in hematopoietic stem cell transplant recipients, with the majority of cases presenting with concurrent hemorrhagic cystitis and HIV-infected patients. The authors report two HIV-infected patients with the diagnosis of BKPyV encephalitis and discuss the main clinical, diagnostic, and therapeutic aspects of this infection in patients with AIDS. Physicians should be aware to recognize the main clinical features and diagnose BKPyV central nervous infection in the setting of AIDS.
PRE AND POST-OPERATIVE OTORHINOLARYNGOLOGY SURGERY CARE IN PATIENTS WITH GLYCOGEN STORAGE DISEASE TYPE 1
Authors: Adriana Maria Alves de Tommaso, Gabriel Hessel, Adriana Gut Riccetto, Graziela de Oliveira Semenzati, Reinaldo Jordão Gusmão
Journal: Rev Paul Pediatr (2019)
MeSH terms: Adenoidectomy, Glycogen Storage Disease Type I / surgery, Middle Ear Ventilation, Perioperative Care / methods, Tonsillectomy, Case Reports, Child, Female, Humans, Glycogen Storage Disease IB

Objective:
To discuss aspects of pre and post-operative otorhinolaryngology surgery in patients with glycogen storage disease type 1b.
Case description:
Description of three clinical cases with probable glycogen storage disease type 1b who underwent otorhinolaryngology surgery, showing the importance of multidisciplinary interaction to avoid episodes of hypoglycemia.
Comments:
Patients with glycogen storage disease type 1b present recurrent infections, including the otorhinolaryngology affections. When there is an indication for surgical treatment, the caloric intake should be carefully followed in order to prevent hypoglycemia. The way to ensure this is to perform the pre and postoperative period in the hospital ward. In the postoperative period, it is important to make a slow transition between the intravenous and oral routes and not suspend the infusion of glucose during the surgical procedure. The cases illustrate the need for the interaction of the otorhinolaryngologic surgeon with the anesthesiologist, the pediatrician and the gastro-pediatrician in the management of these patients, avoiding hypoglycemic episodes.
Right posterior diaphragmatic hernia (Bochdalek) with liver involvement and alteration of hepatic outflow in adult: a case report
Authors: Filippo Banchini, Roberta Santoni, Antonio Banchini, Flavio Cesare Bodini, Patrizio Capelli
Journal: Springerplus (2016)
Keywords: bochdalek, hepatic vein, liver herniation, right diaphragmatic hernia

Introduction:
Posterior right diaphragmatic hernia is rare in newborn patients but when present, is accompanied by high mortality. Pulmonary hypoplasia seems to be the main cause of death but the presence of liver involvement remains one of the reasons for poor prognosis even when intrauterine surgery is performed.
Case description:
In this article, we will present a rare case that was diagnosed by chance in a 65-year old adult presenting with an adenocarcinoma of the rectosigmoid junction and a right Bochdalek hernia with liver herniation and modification of the hepatic vein outflow with a natural right to left shunt.
Discussion:
Diaphragmatic repair was performed on the patient with a mash and simultaneous colorectal resection. Intraoperatively, the exceptional natural modification of the hepatic outflow and alteration of the caval system was evident.
Conclusion:
This case report represent an extremely rare anatomic variation and could be useful to give new important information on the evolution that occur in foetal life.
Delayed surgical treatment for a traumatic bilateral cervical facet joint dislocation using a posterior-anterior approach: a case report
Authors: Takashi Shimada, Seiji Ohtori, Gen Inoue, Junichi Nakamura, Izumi Nakada, Hiroshi Saiki, Song Ho Chang, Koui Kawamura, Kazuhisa Takahashi, Hiroshi Sugiyama
Journal: J Med Case Rep (2013)

Introduction:
There have been few reports of patients with bilateral cervical facet dislocations that remain untreated for eight weeks or more. We report the case of a 76-year-old man with an old bilateral cervical facet joint dislocation fracture that was treated by posterior-anterior reduction and fixation.
Case presentation:
A 76-year-old Asian man was involved in a road traffic accident. He presented with neck pain and arm pain on his right side, but motor weakness and paralysis were not observed. He was treated conservatively; however, instability and spondylolisthesis at the C5 to C6 joint increased eight weeks after the injury. We performed a posterior-anterior reduction and fixation. After surgery, bony union was achieved, and his neck pain and arm pain disappeared.
Conclusion:
We recommend reduction and fixation surgery if a patient has an old bilateral facet joint dislocation fracture in the cervical spine.
Robot-Assisted Perineal Radical Prostatectomy in a Post-Kidney Transplant Recipient
Authors: Volkan Tugcu, Abdulmuttalip Simsek, Ismail Yigitbasi, Mustafa Gurkan Yenice, Selcuk Sahin, Ali Ihsan Tasci
Journal: J Endourol Case Rep (2018)
Keywords: perineal, prostate cancer, prostatectomy, radical, robotics, transplantation
MeSH terms: Case Reports

Background: After almost two decades, transabdominal robotic radical prostatectomy techniques have been fully developed and are widely practiced by many robotic urologists. Recently, a transperineal robotic radical prostatectomy, a technique not yet popular to many, was introduced as an alternative approach in patients with previous abdominal surgery. Here, we present our unique experience with robotic perineal radical prostatectomy (r-PRP) on a kidney transplant recipient. Case Presentation: A 71-year-old man who had a kidney transplant 4 months previously was diagnosed with prostate cancer (PCa) and underwent r-PRP using the da Vinci Xi robotic system. The operative time was 110 minutes and blood loss was minimal. After the perineal drain was removed on postoperative day 3, the patient was discharged. The urethral catheter was subsequently removed on postoperative day 8. Pathologic analysis revealed localized PCa with negative surgical margins. Conclusion: The r-PRP offers all the advantages of minimally invasive surgery. Moreover, in a kidney transplant recipient, it provides additional benefits, such as avoidance of allograft vascular and ureteral injuries, while maintaining an equivalent oncologic efficacy and surgical safety compared with its transabdominal counterpart.
Gastric Necrosis due to Acute Massive Gastric Dilatation
Authors: Ibrahim Aydin, Ahmet Pergel, Ahmet Fikret Yucel, Dursun Ali Sahin, Ender Ozer
Journal: Case Rep Med (2013)

Gastric necrosis due to acute massive gastric dilatation is relatively rare. Vascular reasons, herniation, volvulus, acute gastric dilatation, anorexia, and bulimia nervosa play a role in the etiology of the disease. Early diagnosis and treatment are highly important as the associated morbidity and mortality rates are high. In this case report, we present a case of gastric necrosis due to acute gastric dilatation accompanied with the relevant literature.
Improvement of eosinophilic chronic rhinosinusitis after infection with severe acute respiratory syndrome corona virus 2 during dupilumab therapy: A case report
Authors: Mariko Koike-Ieki, Ryoji Kagoya, Makiko Toma-Hirano, Yuko Sasajima, Ken Ito
Journal: Front Allergy (2023)
Keywords: cytokine balance, dupilumab, dysosmia, eosinophilic chronic rhinosinusitis, severe acute respiratory syndrome corona virus 2
MeSH terms: Case Reports

Eosinophilic chronic rhinosinusitis (ECRS) is an intractable type 2 inflammatory disease of the paranasal sinuses that persists even after endoscopic sinus surgery (ESS) and systemic corticosteroid therapy. Dupilumab, a monoclonal antibody against the shared receptor components of interleukin (IL)-4 and IL-13, is a novel and effective treatment option for ECRS. Herein, an atypical case of ECRS that improved after infection with severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) during dupilumab therapy is reported. A 40-year-old man with a history of ESS for ECRS visited our hospital with complaints of nasal congestion and dysosmia. Nasal endoscopy revealed bilateral nasal polyps occupying the nasal cavity. Computed tomography (CT) revealed a soft tissue density lesion filling all sinuses on both sides. Based on these findings, ECRS recurrence was confirmed; however, 3 years of subsequent corticosteroid therapy did not improve disease activity. Accordingly, dupilumab therapy was initiated, although 6 months of therapy resulted in only slight improvement in ECRS. Eight months after the initiation of dupilumab therapy, the patient was infected with SARS-CoV-2; thereafter, he noticed an improvement in smell. Nasal endoscopy and sinus CT revealed a marked reduction in nasal polyps and soft tissue density lesions of the sinuses, respectively. With continued dupilumab therapy, no re-exacerbation of ECRS was confirmed at the 6-month follow-up from SARS-CoV-2 infection. Currently, there are no reports describing the impact of SARS-CoV-2 infection on ECRS. As such, careful follow-up and accumulation of cases are necessary.
The coincidence of IgA nephropathy and Fabry disease
Authors: Dita Maixnerová, Vladimír Tesař, Romana Ryšavá, Jana Reiterová, Helena Poupětová, Lenka Dvořáková, Lubor Goláň, Michaela Neprašová, Jana Kidorová, Miroslav Merta, Eva Honsová
Journal: BMC Nephrol (2013)
MeSH terms: Fabry Disease / complications, Fabry Disease / diagnosis, Glomerulonephritis, IGA / complications, Glomerulonephritis, IGA / diagnosis, Case Reports, Research Support, Non-U.S. Gov't, Adult, Diagnosis, Differential, Female, Humans, Male

Background:
IgA nephropathy (IgAN) is the most common glomerulonephritis, which may also coexist with other diseases. We present two patients with an unusual coincidence of IgAN and Fabry disease (FD).
Case presentation:
A 26 year-old man underwent a renal biopsy in February 2001. Histopathology showed very advanced IgAN and vascular changes as a result of hypertension. Because of his progressive renal insufficiency the patient began hemodialysis in August 2001. By means of the blood spot test screening method the diagnosis of FD was suspected. Low activity of alpha-galactosidase A in the patient's plasma and leukocytes and DNA analysis confirmed the diagnosis of FD. Enzyme replacement therapy started in July 2004. Then the patient underwent kidney transplantation in November 2005. Currently, his actual serum creatinine level is 250 μmol/l. Other organ damages included hypertrophic cardiomyopathy, neuropathic pain and febrile crisis. After enzyme replacement therapy, myocardial hypertrophy has stabilized and other symptoms have disappeared. No further progression of the disease has been noted.The other patient, a 30 year-old woman, suffered from long-term hematuria with a good renal function. Recently, proteinuria (2.6 g/day) appeared and a renal biopsy was performed. Histopathology showed IgAN with remarkably enlarged podocytes. A combination of IgAN and a high suspicion of FD was diagnosed. Electron microscopy revealed dense deposits in paramesangial areas typical for IgAN and podocytes with inclusive zebra bodies and myelin figures characteristic of FD. FD was confirmed by the decreased alpha-galactosidase A activity in plasma and leukocytes and by DNA and RNA analysis. Enzyme replacement therapy and family screening were initiated.
Conclusions:
Our results emphasize the role of complexity in the process of diagnostic evaluation of kidney biopsy samples. Electron microscopy represents an integral part of histopathology, and genetic analysis plays a more and more important role in the final diagnosis, which is followed by causal treatment.
First case of bioterrorism-related inhalational anthrax, Florida, 2001: North Carolina investigation
Authors: Jean-Marie Maillard, Marc Fischer, Kelly T McKee Jr, Lou F Turner, J Steven Cline
Journal: Emerg Infect Dis (2002)
MeSH terms: Anthrax / epidemiology, Bioterrorism / statistics & numerical data, Environmental Monitoring, Population Surveillance, Case Reports, Anthrax / diagnosis, Decision Trees, Epidemiological Monitoring, Florida / epidemiology, Humans, Inhalation Exposure, Male, Middle Aged, North Carolina / epidemiology, Syndrome

The index case of inhalational anthrax in October 2001 was in a man who lived and worked in Florida. However, during the 3 days before illness onset, the patient had traveled through North Carolina, raising the possibility that exposure to Bacillus anthracis spores could have occurred there. The rapid response in North Carolina included surveillance among hospital intensive-care units, microbiology laboratories, medical examiners, and veterinarians, and site investigations at locations visited by the index patient to identify the naturally occurring or bioterrorism-related source of his exposure.
Psychiatric side effects of chloroquine in COVID-19 patients: two case reports
Authors: Roukaya Benjelloun, Yassine Otheman, Chafik El Kettani
Journal: Pan Afr Med J (2020)
Keywords: covid-19, chloroquine, anxiety, hallucination, psychiatry, side effect
MeSH terms: COVID-19 Drug Treatment, Chloroquine / adverse effects, Case Reports, Adult, Antimalarials / administration & dosage, Antimalarials / adverse effects, Anxiety / chemically induced, Chloroquine / administration & dosage, Female, Humans, Male, Middle Aged, Morocco, Psychoses, Substance-Induced / etiology, Antimalarials, Chloroquine

Chloroquine and hydroxy chloroquine are widely use in Africa and all over the world as anti-malarial drugs but also in the treatment of chronic inflammatory diseases. Since the outbreak of COVID-19 pandemic, Morocco have included this medication in the COVID-19 treatment guidelines in association with azithromycine. Besides dermatologic problems, ocular impairments and gastro-intestinal effects, quinolines may also cause rarely described psychiatric adverse effects. To our knowledge, there has been no reports of psychiatric side effects of chloroquine or hydroxy chloroquine in the actual context of COVID-19 pandemic. Here, we present the description of two COVID-19 patients who showed psychiatric side effects after chloroquine treatment. One patient expressed psychotic symptoms and the other one experienced acute and intense anxiety. In both cases, and according to Naranjo score, the association between chloroquine and psychiatric side effects was probable.
Case report: A hybrid open and endovascular approach for repairing a life-threatening innominate artery dissection using the simultaneous kissing stent technique
Authors: Chu-Hsuan Kuo, Shun-Tai Yang, Yueh-Hsun Lu, Yu-Chun Lu, I-Chang Su
Journal: Front Neurol (2023)
Keywords: arterial dissection, hybrid approach, innominate artery, kissing stent, stenosis
MeSH terms: Case Reports

Managing acute innominate artery (IA) dissection associated with severe stenosis is challenging due to its rarity, possible complex dissection patterns, and compromised blood flow to the brain and upper extremities. This report describes our treatment strategy for this challenging disease using the kissing stent technique. A 61-year-old man had worsening of an acute IA dissection secondary to an extension of a treated aortic dissection. Four possible treatment strategies for kissing stent placement were proposed based on different approaches (open surgical or endovascular) and accesses (trans-femoral, trans-brachial, or trans-carotid access). We chose to place two stents simultaneously via a percutaneous retrograde endovascular approach through the right brachial artery and a combined open surgical distal clamping of the common carotid artery with a retrograde endovascular approach through the carotid artery. This hybrid approach strategy highlights the three key points for maintaining safety and efficacy: (1) good guiding catheter support is obtainable through retrograde, rather than antegrade, access to the lesion, (2) concomitant cerebral and upper extremity reperfusion is guaranteed by placing kissing stents into the IA, and (3) peri-procedural cerebral emboli are prevented by surgical exposure of the common carotid artery with distal clamping.
Successful treatment of methimazole-induced severe aplastic anemia by granulocyte colony-stimulating factor, methylprednisolone, and cyclosporin
Authors: Munehiro Honda
Journal: ISRN Endocrinol (2011)
MeSH terms: Case Reports

A 52-year-old Japanese woman was examined because of general malaise, weight loss and a lump in her left breast. She was diagnosed with cancer of the left breast and Graves' disease, and was administered methimazole (MMI). A left mastectomy was performed for the breast cancer. She presented with a high fever and peripheral blood examination revealed a severe pancytopenia. She was diagnosed with severe aplastic anemia, and administered G-CSF, however, the treatment was unsuccessful. Thus, oral methyprednisolone and cyclosporin were added. There was a remarkable improvement in the peripheral blood count.
Low-Grade Endometrial Stromal Sarcoma in a 22-Year-Old Maiden Female: A Rare Case Report from Syria
Authors: Lana Nseir, Georget Mansour, Junior Makhoul, Luna Skaf, Mohammad Ziad Dahhan, Zuheir AlShehabi
Journal: Case Rep Obstet Gynecol (2021)
MeSH terms: Case Reports

Endometrial stromal sarcoma (ESS) is a rare and challenging type of endometrial tumor, constituting only about 0.2% of all uterine malignancies and occurring in women 42-58 years of age. ESS is usually misdiagnosed as leiomyoma. They both have nonspecific symptoms, which makes the diagnosis of ESS difficult to achieve. As the ESS is infrequently encountered, optimal management is quite debatable. Here, we report a rare case of a 22-year-old Syrian female who presented with abnormal uterine bleeding; the preoperative diagnosis suggested leiomyoma while histopathological and immunohistochemical studies confirmed the diagnosis of LG-ESS stage IIA. Therefore, the treatment plan was shifted from a conservative myomectomy to a total hysterectomy with both adnexa. The aim of this case report is to draw attention to this uncommon tumor at young age of patients as well as to have awareness of the necessity to suspect this diagnosis especially with the presentation of rapid enlargement of uterine leiomyoma.
Juvenile Breast Hypertrophy: A Successful Breast Reduction of 14.9% Body Weight without Recurrence in a 5-Year Follow-Up
Authors: Akmal Hisham, Marzida Abd Latib, Normala Basiron
Journal: Case Rep Surg (2017)
MeSH terms: Case Reports

Juvenile hypertrophy of the breast (JHB) is a rare and relentless disease affecting women in the peripubertal period. We present a 13-year-old girl with massive bilateral JHB, successfully treated with a breast reduction and free nipple graft technique. A total of 7300 grams of breast tissue had been removed, accounting for 14.9% of the patient's total body weight. Prophylactic hormonal therapy was not commenced. During the 5-year follow-up period, there was no recurrence and the patient remains satisfied with the aesthetic outcome. A recent meta-analysis study indicates that subcutaneous mastectomy is associated with reduced risk of recurrence, but it is more deforming and the aesthetic result is inferior to a reduction mammaplasty. In patients treated with the latter technique, some evidence exists suggesting that the use of a free nipple graft is associated with a less frequent risk of recurrence than a pedicle technique. This present case is unique as it demonstrates the clinical course of this patient at a considerably longer follow-up period than most reported studies. We adhered to the limited available evidence and highlight the long-term reliability of breast reduction with free nipple grafting as the first line surgical option in JHB, eliminating the need for repeated surgeries.
Topical vitamin A treatment of recalcitrant common warts
Authors: Anca Gaston, Robert F Garry
Journal: Virol J (2012)
MeSH terms: Skin Diseases, Viral / drug therapy, Vitamin A / administration & dosage, Warts / drug therapy, Case Reports, Administration, Topical, Adult, Female, Hand / pathology, Humans, Skin Diseases, Viral / pathology, Treatment Outcome, Warts / pathology, Vitamin A

Background:
Common warts (verruca vulgaris) are benign epithelial proliferations associated with human papillomavirus (HPV) infection. Salicylic acid and cryotherapy are the most frequent treatments for common warts, but can be painful and cause scarring, and have high failure and recrudescence rates. Topical vitamin A has been shown to be a successful treatment of common warts in prior informal studies.
Case:
The subject is a healthy, physically-active 30 old female with a 9 year history of common warts on the back of the right hand. The warts resisted treatment with salicylic acid, apple cider vinegar and an over-the-counter blend of essential oils marketed for the treatment of warts. Daily topical application of natural vitamin A derived from fish liver oil (25,000 IU) led to replacement of all the warts with normal skin. Most of the smaller warts had been replaced by 70 days. A large wart on the middle knuckle required 6 months of vitamin A treatment to resolve completely.
Conclusion:
Retinoids should be further investigated in controlled studies to determine their effectiveness in treating common warts and the broad range of other benign and cancerous lesions induced by HPVs.
Augmented Total Elbow Arthroplasty with Femoral Strut Allograft for Revision of Prosthetic Joint Infection with Distal Humerus Bone Loss and Incomplete Union of Periprosthetic Humeral Shaft Fracture
Authors: William R Monahan, Elizabeth Alaimo, Jared M Mahylis
Journal: Case Rep Orthop (2021)
MeSH terms: Case Reports

Total elbow arthroplasty (TEA) prosthetic joint infection (PJI) in the setting of distal humerus bone loss poses a challenge for restoration of function. This can be complicated by a periprosthetic humeral fracture. Revision surgery in the setting of these pathologies possesses a significant challenge, especially when two or, in this case, all three problems are treated simultaneously. We present the clinical course, operative findings, and definitive treatment with the use of an augmented total elbow arthroplasty and femoral strut allograft reinforcement in detail. A review of the literature regarding the identification and management of infected TEA with augmented prosthesis and bone allograft augmentation of humerus fractures will be outlined in this case report.