OpenMed/multicare-articles huggingface dataset:
Dynamic CT perfusion imaging of the myocardium: a technical note on improvement of image quality
Authors: Daniela Muenzel, Sven Kabus, Bettina Gramer, Vivian Leber, Mani Vembar, Holger Schmitt, Moritz Wildgruber, Alexander A Fingerle, Ernst J Rummeny, Armin Huber, Peter B Noël
Journal: PLoS One (2013)
MeSH terms: Heart / diagnostic imaging, Myocardial Perfusion Imaging / methods, Myocardium / pathology, Tomography, X-Ray Computed / methods, Case Reports, Research Support, Non-U.S. Gov't, Aged, 80 and over, Humans, Male, Middle Aged

Objective:
To improve image and diagnostic quality in dynamic CT myocardial perfusion imaging (MPI) by using motion compensation and a spatio-temporal filter.
Methods:
Dynamic CT MPI was performed using a 256-slice multidetector computed tomography scanner (MDCT). Data from two different patients-with and without myocardial perfusion defects-were evaluated to illustrate potential improvements for MPI (institutional review board approved). Three datasets for each patient were generated: (i) original data (ii) motion compensated data and (iii) motion compensated data with spatio-temporal filtering performed. In addition to the visual assessment of the tomographic slices, noise and contrast-to-noise-ratio (CNR) were measured for all data. Perfusion analysis was performed using time-density curves with regions-of-interest (ROI) placed in normal and hypoperfused myocardium. Precision in definition of normal and hypoperfused areas was determined in corresponding coloured perfusion maps.
Results:
The use of motion compensation followed by spatio-temporal filtering resulted in better alignment of the cardiac volumes over time leading to a more consistent perfusion quantification and improved detection of the extend of perfusion defects. Additionally image noise was reduced by 78.5%, with CNR improvements by a factor of 4.7. The average effective radiation dose estimate was 7.1±1.1 mSv.
Conclusion:
The use of motion compensation and spatio-temporal smoothing will result in improved quantification of dynamic CT MPI using a latest generation CT scanner.
Encrusted Ureteral Stent Retrieval Using Flexible Ureteroscopy with a Ho: YAG Laser
Authors: Takashi Kawahara, Hiroki Ito, Hideyuki Terao, Takehiko Ogawa, Hiroji Uemura, Yoshinobu Kubota, Junichi Matsuzaki
Journal: Case Rep Med (2012)
MeSH terms: Case Reports

A 23-year-old female had bilateral ureteral stents placed due to bilateral renal stones and hydronephrosis. The bilateral ureteral stents were changed every 3 months. A kidney ureter bladder (KUB) film showed left encrustation along the ureteral stent thus necessitating removal; however, the ureteral stent could not be removed cystoscopically. The ureteral stent was, therefore, extracted using flexible ureteroscopy (URS) with a holmium (Ho): yttrium aluminum garnet (YAG) laser.
Role of Confocal Laser Endomicroscopy in Detection of Residual Barrett's Esophagus after Radiofrequency Ablation
Authors: Giorgio Diamantis, Paolo Bocus, Stefano Realdon, Giorgio Battaglia
Journal: Case Rep Gastrointest Med (2011)
MeSH terms: Case Reports

Endoscopic endoluminal radiofrequency ablation (RFA) is a novel and promising modality for Barrett's esophagus (BE) treatment. Actually the only surveillance method after the ablation treatment is random biopsies throughout the whole treated area. Confocal laser endomicroscopy (CLE) is a new endoscopic imaging tool that permits high-resolution microscopic examination of the gastrointestinal tract. The technology has garnered increasing attention because of its ability to provide real-time "optical" biopsy specimens, with a very high sensitivity and specificity. This paper summarize the potential application of CLE in the surveillance of the reepithelialization of BE, after endoscopic RFA.
Extracorporeal Membrane Oxygenation in Severe Acute Eosinophilic Pneumonia
Authors: Sean C Dougherty, Sophia Ghaus, Orlando Debesa
Journal: Front Med (Lausanne) (2019)
Keywords: ards, ecmo, acute eosinophilic pneumonia, bronchoalveolar lavage, pulmonary eosinophilia
MeSH terms: Case Reports

Acute Eosinophilic Pneumonia (AEP) is a potentially fatal cause of hypoxemic respiratory failure characterized by fever, diffuse bilateral pulmonary infiltrates, and pulmonary eosinophilia. Shown to be associated with a number of environmental exposures and lifestyle choices, AEP has a good prognosis when diagnosed early and treated with corticosteroids. In this clinical case report, we detail the presentation, evaluation, diagnosis, and management of a 40-year old male who presented to the emergency department with dyspnea, chills, and diaphoresis. He had a history of pulmonary embolism 8 years prior but was otherwise healthy, though he had re-started smoking cigarettes a week prior to presentation. Initial chest CT scan revealed widespread mixed groundglass and solid airspace opacities; over the next 12 hours, he rapidly decompensated and after not responding to other invasive mechanical ventilation, was emergently cannulated for veno-venous extracorporeal membrane oxygenation (V-V ECMO). Bronchoalveolar lavage later revealed pulmonary eosinophilia, and after an infectious workup was negative, a diagnosis of AEP was reached and the patient was started on corticosteroids. To our knowledge, this is one of few published cases of AEP requiring V-V ECMO for clinical stabilization, highlighting the utility of this treatment modality in severe disease.
Undifferentiated carcinoma of the pituitary gland: A case report and review of the literature
Authors: Hsun-Hwa Lee, Shih-Han Hung, Te-Ming Tseng, Yun-Ho Lin, Ju-Chuan Cheng
Journal: Oncol Lett (2014)
Keywords: cancer, irradiation, pituitary gland, radiotherapy, undifferentiated carcinoma

Primary pituitary gland cancer is extremely rare. The current study presents the case of a patient diagnosed with pituitary cancer three months after completing surgery and post-operative chemoradiotherapy for hypopharyngeal cancer. In this report we discuss 57-year-old patient who presented with diplopia and ptosis four months following the completion of treatment for hypopharyngeal cancer. A poorly-differentiated pituitary carcinoma was located. Despite aggressive treatment and surgical excision with postoperative chemoradiotherapy, the disease progressed rapidly and the patient succumbed due to multiple metastases and organ failure. This case report indicates a possible correlation between irradiation and the development of pituitary cancer.
Undiagnosed apical hypertrophic cardiomyopathy in an old amateur soccer player: a case report
Authors: Mahassine El Harras, Ilham Bensahi, Salma Abdeladim, Fatimazahra Merzouk, Amal Elouarradi, Sara Oualim, Mohamed Sabry
Journal: Pan Afr Med J (2021)
Keywords: hypertrophic cardiomyopathy, apical hypertrophic cardiomyopathy, case report, sport cardiology
MeSH terms: Cardiomyopathy, Hypertrophic / diagnosis, Soccer, Case Reports, Chest Pain / etiology, Echocardiography, Electrocardiography, Heart Ventricles, Humans, Male

Hypertrophic cardiomyopathy is a primary muscle disorder characterized by an abnormal thickness of the left ventricular wall. It is often going undiagnosed because many patients have few symptoms and can lead normal lives. This is a case report about an apical cardiomyopathy diagnosed at a very late stage in an old amateur soccer player. He was hospitalized due to acute chest pain; neurologic disorder related to a hypertensive emergency, he underwent successful percutaneous coronary intervention, echocardiography and CMR revealed Apical hypertrophic cardiomyopathy. The development of sports cardiology has major importance in the detection of cardiac disease which may have poor prognosis. Our patient had the chance to achieve his entire career without rhythmic complications.
The Root Membrane Technique: Human Histologic Evidence after Five Years of Function
Authors: Miltiadis E Mitsias, Konstantinos D Siormpas, Georgios A Kotsakis, Scott D Ganz, Carlo Mangano, Giovanna Iezzi
Journal: Biomed Res Int (2017)
MeSH terms: Dental Implantation, Endosseous / methods, Dental Implants, Maxilla / surgery, Tooth Root / surgery, Case Reports, Dental Prosthesis Design / methods, Humans, Male, Middle Aged, Osseointegration / physiology, Periodontal Ligament / physiopathology, Periodontal Ligament / surgery, Dental Implants

Background:
The "root membrane" (RM) is a technique that has become popular among implantologists for placement of immediate implants in the anterior maxilla.
Purpose:
To present histologic evidence of an immediate implant placed in the human anterior maxilla, according to the RM technique, and retrieved after five years.
Methods:
A fixture, along with the surrounding tissues, was retrieved from the anterior maxilla of a 68-year-old patient, who had been treated five years earlier with immediate implant placement and RM technique. The specimen was processed for histologic/histomorphometric evaluation.
Results:
The buccal bone plate was maintained without any resorption; a healthy periodontal ligament was evidenced. The implant showed osseointegration, with a high percentage of bone-to-implant contact (BIC = 76.2%). With regard to the space between the RM and the implant, the apical and medial thirds were filled with compact, mature bone; the coronal third was colonized by noninfiltrated connective tissue.
Conclusions:
The RM technique appears to be effective in preventing bone resorption of the buccal bone plate of the human anterior maxilla, five years after the placement of an immediate implant.
Prevalence and clinical characteristics of Crooke's cell adenomas in 101 patients with T-PIT-positive pituitary adenomas: Case series and literature review
Authors: Dimin Zhu, Zongming Wang, Tian Tian, Xinyi Wu, Dongsheng He, Yonghong Zhu, Dawei Liu, Haijun Wang
Journal: Front Endocrinol (Lausanne) (2022)
Keywords: acth, crooke’s cell, cushing disease, hyalinization, pituitary adenoma
MeSH terms: Adenoma / pathology, Cushing Syndrome / pathology, Pituitary Neoplasms / pathology, Review, Research Support, Non-U.S. Gov't, Female, Humans, Male, Neoplasm Recurrence, Local, Prevalence, Retrospective Studies

Purpose:
We aimed to perform a retrospective analysis of a rare subtype of corticotroph adenoma, Crooke's cell adenoma, to better understand its clinical features.
Methods:
We collected T-PIT-positive pituitary adenomas and screened Crooke's cell adenomas from January 2020 to December 2021 in our center. Case reports of such tumors were also collected through a literature search. Clinical data such as biochemical tests, imaging examinations, and pathological data of the above cases were analyzed.
Results:
A total of 101 T-PIT-positive patients were treated in our center in the last 2 years, and 4 were finally pathologically diagnosed with Crooke's cell adenomas. All of these patients were male with elevated adrenocorticotropic hormone levels, and 50.0% presented with hypercortisolemia, Cushing's syndrome, visual impairment, and headache. The tumor diameter was significantly larger in these 4 patients (37.0 mm) than in the other patients (26.0 mm), and their tumor invasive behavior was more pronounced. Cases reported in the literature were mainly female (72.8%), and the clinical presentation was also dominated by Cushing's syndrome (65.1%) and hormonal dysfunction. Tumors were more common as macroadenomas (33.2 mm) and suprasellar growths (63.8%). The tumor recurrence rate was as high as 55.6%, with 6 cases progressing to pituitary carcinomas and 7.7% of tumor-related deaths. Our further integrated analysis of our center and reported cases revealed that gender, Cushing's syndrome, visual dysfunction, hormonal disorders, and tumor growth characteristics were statistically different in different tumor categories.
Conclusion:
Crooke's cell adenoma is a tumor subtype with obvious clinical aggressive behavior, and an in-depth analysis of its clinical characteristics may assist in developing a comprehensive treatment plan.
Conservative Treatment for Right Ventricular Free Wall Rupture in a Patient with Acute Myocardial Infarction
Authors: Mohd Al-Baqlish Mohd Firdaus, Nur Syahirah Abdul Rahim, Nurtasneem Rusdi, Nor Saadah Idris, Mohd Ridzuan Mohd Said, Imran Zainal Abidin
Journal: Case Rep Cardiol (2020)
MeSH terms: Case Reports

Ventricular wall rupture possesses a high mortality rate in patients with acute myocardial infarction. We presented a case of a ninety-year-old gentleman who presented with acute inferolateral myocardial infarction in cardiogenic shock and right ventricular free wall rupture. He was treated conservatively and survived.
Angelman Syndrome due to familial translocation: unexpected additional results characterized by Microarray-based Comparative Genomic Hybridization
Authors: Emiy Yokoyama-Rebollar, Adriana Ruiz-Herrera, Esther Lieberman-Hernández, Victoria Del Castillo-Ruiz, Silvia Sánchez-Sandoval, Silvia M Ávila-Flores, José Luis Castrillo
Journal: Mol Cytogenet (2015)
Keywords: 15q112, angelman syndrome, translocation, array cgh
MeSH terms: Case Reports

Background:
The 15q11q13 region is subject to imprinting and is involved in various structural rearrangements. Less than 1% of Angelman Syndrome patients are due to translocations involving 15q11q13. These translocations can arise de novo or result from the segregation of chromosomes involved in a familial balanced translocation.
Results:
A 5-year-old Mexican girl presented with developmental delay, minor dysmorphic features and history of exotropia. G-banding chromosome analysis established the diagnosis of Angelman Syndrome resulting from a familial translocation t(10;15) involving the 15q11.2 region. The available family members were studied using banding and molecular cytogenetic techniques, including Microarray-based Comparative Genomic Hybridization, which revealed additional unexpected results: a coincidental and smaller 15q deletion, asymptomatic duplications in 15q11.2 and Xp22.31 regions.
Conclusions:
This report demonstrates the usefulness of array CGH for a detailed characterization of familial translocations, including the detection of submicroscopic copy number variations, which would otherwise be missed by karyotype analysis alone. Our report also expands two molecularly characterized rare patient cohorts: Angelman Syndrome patients due to familial translocations and patients with 15q11.2 duplications of paternal origin.
Papillary Thyroid Cancer in a Child with Progressive Transformation of Germinal Centers
Authors: Suresh Mohan, Bradley DeNardo, Dariusz Stachurski, Jennifer Greene Welch, Jan C Groblewski
Journal: Case Rep Otolaryngol (2016)

Objectives. To describe the presentation and management of a child with Progressive Transformation of Germinal Centers (PTGC), an uncommon condition characterized by significant persistent lymphadenopathy, who developed papillary thyroid carcinoma and to explore and review potential links between PTGC and neoplastic processes in the head and neck. Methods. Case presentation and literature review are used. Results. A 10-year-old female presented with a right parotid mass and cervical lymphadenopathy. Multiple biopsies revealed PTGC without malignancy. Two years later, she developed fatigue and weight gain, and a thyroid nodule was found. Fine needle aspiration was strongly suggestive of papillary thyroid carcinoma. The patient underwent total thyroidectomy and central neck dissection without surgical management of the longstanding right lateral neck lymphadenopathy. Final pathology confirmed papillary thyroid carcinoma. She was treated with radioactive iodine therapy postoperatively and remains free of disease at three years of follow-up. Conclusions. PTGC is considered a benign condition but has previously been associated with Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL). This is the first reported case of papillary thyroid cancer in a child with preexisting cervical PTGC and no defined risk factors for thyroid malignancy. No link has been established with thyroid carcinoma, but patients with PTGC may have a defect in immune surveillance that predisposes them to malignancy.
Clinical Application of the PES/WES Index on Natural Teeth: Case Report and Literature Review
Authors: Alessandro Lanza, Fabrizio Di Francesco, Gennaro De Marco, Felice Femiano, Angelo Itro
Journal: Case Rep Dent (2017)
MeSH terms: Case Reports

The use of reliable indices to evaluate the aesthetic outcomes in the aesthetic area is an important and objective clinical aid to monitor the results over time. According to the literature various indices were proposed to evaluate aesthetic outcomes of implant-prosthetic rehabilitation of the anterior area like Peri-Implant and Crown Index [PICI], Implant Crown Aesthetic Index [ICAI], Pink Esthetic Score/White Esthetic Score [PES/WES], and Pink Esthetic Score [PES] but none of them was related to prosthetic rehabilitation on natural teeth. The aim of this study is to verify the validity of PES/WES index for natural tooth-prosthetic rehabilitation of the anterior area. As secondary objective, we proposed to evaluate the long-term predictability of this clinical application, one of which is presented below, following the analysis of the most currently accepted literature.
Fatal Postpartum Hemorrhage in a Patient with Niemann-Pick Disease Type B
Authors: Atakan Tanacan, Abdullah Yalcin, Canan Unal, Seda Banu Akinci, Mehmet Sinan Beksac
Journal: Case Rep Obstet Gynecol (2018)
MeSH terms: Case Reports

Background:
Niemann-Pick Disease Type B (NPD B) is a rare lysosomal storage disorder resulting from an inherited deficiency of acid sphingomyelinase activity. Here, we report the case of a splenectomized patient with NPD B who died because of severe postpartum hemorrhage (PPH).
Case presentation:
A 23-year-old nulliparous woman was admitted to intensive care unit (ICU) after cardiopulmonary arrest during urgent hysterectomy because of severe postpartum bleeding. The patient concealed her disease from her family and obstetricians during her pregnancy, and her NPD B diagnosis was revealed during her stay in ICU while searching for the cause of the splenectomy and severe bleeding. Unfortunately, she had a detrimental course with hypoxic brain injury leading to brain death.
Conclusions:
In conclusion, physicians should keep in mind that patients with a history of splenectomy and/or uncontrollable hemorrhage must be carefully evaluated for rare diseases like lysosomal storage diseases and that NPD B can cause mortality because of postpartum bleeding. Adult intensivists should be familiar with adult presentations of rare metabolic or genetic diseases as more and more children with metabolic or genetic diseases will survive to adulthood and will be admitted to and unfortunately will even die in the adult ICU.
A metastasizing squamous cell carcinoma arising in a solitary epidermal nevus
Authors: Masami Toya, Yuichiro Endo, Akihiro Fujisawa, Miki Tanioka, Yoshiaki Yoshikawa, Takao Tachibana, Yoshiki Miyachi
Journal: Case Rep Dermatol Med (2012)

Aim. Secondary tumor rarely develops from epidermal nevus. We present a case of a metastasizing squamous cell carcinoma that developed in a solitary epidermal nevus. Case Report. An 82-years old Japanese female was presented with a red tumor on the left axilla. She reported that the tumor developed in a congenital epidermal nevus. A biopsy of the tumor showed that a well-differentiated squamous cell carcinoma (SCC) arose from the epidermal nevus. As a lymph node metastasis was found by sentinel lymph node biopsy, the patient received surgical excision of the lesion, axillary lymph node dissection, and postoperative radiation. Discussion. Secondary tumors developing in epidermal nevus are rare. To the best of our knowledge, only in two cases including the present case, SCC developed in a solitary epidermal nevus. There is no established clinical guideline for prophylactic removal of epidermal nevus. However, a biopsy should be done if a secondary malignancy is suspected in an epidermal nevus.
Spindle cell hemangioendothelioma of the temporal muscle resected with zygomatic osteotomy: a case report of an unusual intramuscular lesion mimicking sarcoma
Authors: Tomohiro Minagawa, Takeshi Yamao, Ryuta Shioya
Journal: Case Rep Surg (2011)
MeSH terms: Case Reports

Spindle cell hemangioendothelioma (SCH) was originally described by Weiss and Enzinger (1986) as a low-grade angiosarcoma resembling both cavernous hemangioma and Kaposi's sarcoma. Recent studies suggest that SCH is a benign neoplasm or reactive lesion accompanying a congenital or acquired vascular malformation. Most SCHs present as one or more nodules affecting the dermis or subcutis of the distal extremities. Few reports describe SCH of the head and neck region; even fewer note intramuscular SCH. Here, we describe a case of SCH involving the temporal muscle mimicking soft tissue sarcoma, who had a successful surgical treatment with a coronal approach and zygomatic osteotomy.
Recurrence of Primary Vascular Leiomyosarcoma Five Years after Initial Diagnosis in the Lower Extremity
Authors: Hilal Erinanc, Mehmet Ozulku, Aysen Terzi
Journal: Case Rep Oncol Med (2018)
MeSH terms: Case Reports

Primary leiomyosarcomas of vascular origin are rare tumors. They frequently arise within the inferior vena cava; however, the peripheral vein was also affected. To date, only a few hundred cases have been reported in the world literature. Although it is an extremely aggressive tumor, the symptoms may be unspecific, especially in the lower extremities. In this report, we present a case of primary vascular leiomyosarcoma, arising from the short saphenous vein, with symptoms mimicking thrombus in the initial diagnosis. The diagnosis of leiomyosarcomas was confirmed by standard H&E staining and immunohistochemical staining. Recurrence of the tumor has been observed five years after surgical treatment. Due to its rarity, experience in the management of this type of tumor is limited. The mainstay of treatment for these tumors is complete surgical resection. The purpose of the presented case is to discuss the clinicopathological features and management options of this tumor, under the light of the most recent literatures.
A severed IP ligament as a cause for trans-vaginal uterine bleeding post termination of pregnancy: a case report
Authors: Madeeha Dean, Nicole Stamatopoulos, Thierry Vancaillie
Journal: Pan Afr Med J (2017)
Keywords: gynaecology, curettage, dilatation, pregnancy, surgery
MeSH terms: Abortion, Induced / adverse effects, Ligaments / injuries, Uterine Hemorrhage / etiology, Uterine Perforation / etiology, Case Reports, Abortion, Induced / methods, Adult, Australia, Fallopian Tubes / pathology, Female, Humans, Ovary / pathology, Pregnancy, Pregnancy Trimester, Second

Uterine perforation is an uncommon yet serious complication of surgical management of first and second trimester termination of pregnancies. The rate of uterine perforation is under reported, as patients are usually asymptomatic. Although uncommon, uterine perforation can cause life-threatening complications for some patients. This case report discusses a second trimester surgical termination resulting in uterine perforation and haemorrhage secondary to an avulsion of the infundibulopelvic ligament and prolapse of the left fallopian tube and ovary into the uterine cavity. A literature search was undertaken to compare this case report to those previously published. To the best of our knowledge, this is the first case report in Australia that discusses a unique case of a severed infundibulo-pelvic ligament as a cause for trans-vaginal uterine bleeding post second trimester termination of pregnancy.