OpenMed/multicare-articles huggingface dataset:
Case Report: Usefulness of Biomarkers for Alzheimer's Disease in Two Cases With Very-Late-Onset Schizophrenia-Like Psychosis
Authors: Yuto Satake, Hideki Kanemoto, Kenji Yoshiyama, Ryoko Nakahama, Keiko Matsunaga, Eku Shimosegawa, Takashi Morihara, Mamoru Hashimoto, Manabu Ikeda
Journal: Front Psychiatry (2021)
Keywords: amyloid pet, case report, cerebrospinal fluid, prodromal alzheimer's disease, very-late-onset schizophrenia-like psychosis
MeSH terms: Case Reports

The association between primary psychotic disorders emerging in later life and neurodegenerative diseases, including Alzheimer's disease (AD), is controversial. We present two female non-demented cases of psychosis with onset above the age of 60 years. Cases 1 and 2 were aged was 68 and 81 years, respectively. They suffered from persecutory delusions and scored 28 on the Mini-Mental State Examination (MMSE) at the first examination. Although detailed neuropsychological tests detected amnesia, they had preserved daily life function. Brain magnetic resonance imaging, N-isopropyl-p-[123I] iodoamphetamine (123I-IMP) single-photon emission computed tomography, and cardiac [123I]-metaiodobenzylguanidine (123I-MIBG) scintigraphy showed no specific abnormalities in either case. We diagnosed them with very-late-onset schizophrenia-like psychosis (VLOSLP) because there was no evidence that their psychoses were derived from organic diseases or affective disorders. Upon close inspection, the AD biomarkers, cerebrospinal fluid (CSF) testing and Florbetapir F 18 positron emission tomography (PET), were positive in Case 1 and negative in Case 2. Case 1 scored 25 1 year later and 23 2 years later on the MMSE and was finally diagnosed as AD dementia. These two cases suggest that some clinically diagnosed VLOSLPs may be a prodromal AD. Although VLOSLP is a disease entity supposed to be a primary psychotic disorder, some are probably secondary psychosis with insidious neurodegeneration. Advanced biomarkers such as amyloid PET and CSF may contribute to the detection of secondary psychosis from clinically diagnosed VLOSLP.
Health Informatics on Adolescents Smoking Based on the Miryoku Engineering Analysis Framework
Authors: Jia-Xuan Han, Kun Wang
Journal: J Healthc Eng (2021)
MeSH terms: Medical Informatics, Smoking Cessation / methods, Retracted Publication, Adolescent, Humans, Smoking

Smoking among young people has aroused widespread concern in society. The number of young people who smoke has increased year by year, which has largely affected their health. Therefore, how to improve the prevention and control rate of tobacco harm, thereby reducing the smoking rate of young people has become an important issue. Based on the glamour engineering research method that can specifically solve the problem of attractiveness between users and products, the user preference of young people's smoking behavior is studied through the evaluation structure method and quantitative type I analysis, and the potential attractive factors are analyzed. Among them, there are 7 important attractive characteristics that affect the first attempt to smoke. These seven factors are divided into two aspects, namely, personal preference factors and environmental factors. The statistical data obtained through data analysis will be tested in the KMO field. The KMO values are 0.827 and 0.687, respectively, and the statistical results have obvious scores, so this study is effective. By quantifying one category, the partial correlation coefficients of different categories can be found, that is, specific solutions. This method provides a reference for ways and means to curb smoking behavior and also provides a case study for studying user perception. According to the research results, we seek ways to influence the smoking preferences of young people and then adopt some artificial methods to intervene in the generation of these factors, so as to achieve the purpose of reducing smoking among young people.
Coexistence of p190 BCR/ABL Transcript and CALR 52-bp Deletion in Chronic Myeloid Leukemia Blast Crisis: A Case Report
Authors: Mohammad Seghatoleslami, Neda Ketabchi, Alireza Ordo, Javad Mohammadi Asl, Neda Golchin, Najmaldin Saki
Journal: Mediterr J Hematol Infect Dis (2016)
MeSH terms: Case Reports

We introduce a 78-year-old woman presented with thrombocytosis and high blast count who had a history of splenectomy. Her cytogenetic analysis revealed aberrant chromosomal rearrangements in different clonal populations harboring 46XX karyotype with t(9;22) (q34;q11). RT-PCR assay detected the e1a2 BCR-ABL translocation resulting from rearrangement of the minor breakpoint cluster region (m-bcr) in BCR gene. Subsequent evaluation of the disease showed calreticulin (CALR) 52-bp deletion as well as the absence of JAK2 (V617F) heterozygous mutation in granulocyte population of peripheral blood using allele-specific PCR and bi-directional DNA sequencing. To our knowledge, this is the first case of a patient initially diagnosed as p190 BCR-ABL transcript positive CML in blast crisis characterized by a 52-bp deletion in CALR gene.
Intramuscular Myxoma of the Intrinsic Muscles of the Tongue: A Case Report with Literature Review
Authors: Naoko Tsunoda, Kei Onodera, Yu Ohashi, Tadashi Kawai, Ikuya Miyamoto, Yasunori Takeda, Hiroyuki Yamada
Journal: Case Rep Dent (2022)
MeSH terms: Case Reports

Myxoma is a benign tumor of mesenchymal origin. It frequently occurs in the muscles of the hip and extremities; however, it rarely occurs in the head and neck region. This report describes the second case of an intramuscular myxoma of the tongue. A 23-year-old woman was referred to our institution for the diagnosis and treatment of a left tongue lesion. T2-weighted magnetic resonance imaging revealed an 8 × 6-mm mass in the tongue. Based on a clinical diagnosis of a tongue tumor, excisional biopsy was performed under general anesthesia. The histopathological diagnosis was an intramuscular myxoma. The postoperative course was uneventful, and there was no evidence of tumor recurrence 3 years after surgery.
Rare location of head and neck adenoid cystic carcinoma
Authors: Asmaa Naim, Amal Hajjij, Faycal Abbad, Amal Rami, Mustapha Essaadi
Journal: Pan Afr Med J (2019)
Keywords: adenoid cystic carcinoma, laryngeal tumor, minor salivary gland cancer
MeSH terms: Carcinoma, Adenoid Cystic / diagnosis, Head and Neck Neoplasms / diagnosis, Laryngeal Neoplasms / diagnosis, Thyroid Neoplasms / diagnosis, Case Reports, Review, Adult, Carcinoma, Adenoid Cystic / pathology, Carcinoma, Adenoid Cystic / therapy, Female, Head and Neck Neoplasms / pathology, Head and Neck Neoplasms / therapy, Humans, Laryngeal Neoplasms / therapy, Laryngectomy, Patient Care Team / organization & administration, Thyroid Neoplasms / therapy, Thyroidectomy

Adenoid Cystic Carcinoma of larynx is extremely rare location. We herein describe an unusual clinical and radiological presentation of ACCL and review recent literature. We report a case of a 38-year-old woman with history of asthma, presented to our department with acute inspiratory dyspnea that required an emergency tracheotomy. Physical examination revealed a large anterior cervical mass without any lymphadenopathy suspecting thyroid origin. Cervical Computed Scan showed a tumor process between the thyroid lobe, the left edge of the subglottic area and first tracheal rings filling all the lumen, discussing either a laryngo-tracheal or thyroid origin. The patient underwent a panendoscopy under general anesthesia that confirmed a subglottic extension of the tumor and multiples biopsies showed a malignant salivary origin of the mass. After multidisciplinary discussion, the patient underwent total laryngectomy and thyroidectomy with bilateral selective neck dissections (levels II- IV). Anatomopathological examination confirmed the laryngeal location of Adenoid Cystic Carcinoma classified pT4aN0R0. Adjuvant radiation therapy was indicated. In our knowledge, only 10 cases were reported in the literature with this unusual presentation. Moreover, the case we report is in the subglottic floor without invasion of neither vocal cords nor trachea. Total laryngectomy with neck dissection remains the recommended therapeutic procedure for locally advanced ACCL. Adverse features such as close or positive margins, T3-4, intermediate or high grade neural and perineural spread, lymphatic or vascular invasion or lymph node metastases should indicate adjuvant treatment to improve the outcome. The lack of randomized multicentric study, implies the management of ACCL by skilled multidisciplinary team, to suggest adequate personalized treatment.
Ventilator-associated pneumonia caused by Chryseobacterium indologenes: a rare infant case and review of the literature
Authors: Serkan Atıcı, Zeynep Alp Ünkar, Kübra Erdem, Eda Kepenekli Kadayifci, Ayşe Karaaslan, Aslı Çınar Memişoğlu, Ahmet Soysal, Nurver Ülger Toprak, Güner Söyletir, Eren Özek, Mustafa Bakır
Journal: Springerplus (2016)
Keywords: chryseobacterium indologenes, infant case, ventilator-associated pneumonia

Background:

Chryseobacterium indologenes is an uncommon organism that has been documented to cause a variety of invasive infections mostly in hospitalized patients with severe underlying diseases.
Case presentation:
A three-month-old female infant born at term by caesarean section with meningomyelocele and congenital diaphragmatic hernia had two surgeries for the repair of meningomyelocele and diaphragmatic hernia on her 3rd and 14th day, respectively. On the 3rd month of her life, she deteriorated clinically with fever, leukocytosis and increase of acute-phase reactants. Gas exchange condition became worse than it was before. Respiratory secretions, oxygen requirements and ventilator demand increased. Chest X-ray showed bilateral pulmonary infiltrates. Bacteriological blood, urine and cerebrospinal fluid culture test results were negative. C. indologenes was isolated from tracheobronchial secretion sample obtained by endotracheal aspiration. Although susceptible to ciprofloxacin (MIC:0.5 gr/L), levofloxacin and piperacillin-tazobactam, the isolate was resistant to meropenem, imipenem and colistin. She was treated with ciprofloxacin successfully. Her fever resolved and gas exchange condition improved after 72 h of the treatment. The antibiotic treatment was given for a course of 14 days.
Conclusion:

Chryseobacterium indologenes may emerge as a potential pathogen in infants with the factors such as invasive equipment, having underlying diseases and prolonged hospitalization.
Non-surgical management for air injection injury to the hand, a case report
Authors: William Pipkin, Alex Frangenberg, Michael Wade, Weston Peine, William F Pientka 2nd
Journal: Case Reports Plast Surg Hand Surg (2022)
Keywords: hand injection injuries, air injection injury
MeSH terms: Case Reports

We present a case a high pressure air injection injury to the index finger with air extension proximal to the elbow. This patient was treated non-surgically with close observation. At 3 year follow-up, no lasting deficits or complications were noted and radiographs revealed complete resolution of the air tissue dissection.
Successful Treatment of Recalcitrant Granuloma Gluteale Infantum with Topical Tacrolimus 0.03% Ointment
Authors: Alexander K C Leung, Kin Fon Leong, Joseph M Lam
Journal: Case Rep Pediatr (2021)
MeSH terms: Case Reports

Granuloma gluteale infantum is a rare complication of irritant contact dermatitis. For the treatment of granuloma gluteale infantum, the diaper area should be kept clean and dry and the source of skin irritation should be removed or mitigated. For those infants who fail to respond to the conservative management, the use of topical calcineurin inhibitors should be considered. We report the successful treatment of a 12-month-old infant with recalcitrant granuloma gluteale infantum with the use of topical tacrolimus 0.03% ointment. To our knowledge, this is the second case reporting the use of topical calcineurin inhibitors in the treatment of recalcitrant granuloma gluteale infantum.
Long-Term Follow-Up of SAPHO Syndrome for 15 Years Led to a Diagnosis of Temporomandibular Joint Pain and Trismus
Authors: Koki Takamatsu, Hitoshi Sato, Takashi Moriya, Arisa Yasuda, Takaaki Kamatani, Tatsuo Shirota
Journal: Case Rep Dent (2021)
MeSH terms: Case Reports

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a systemic disease with symptoms of pustular skin disease and sterile osteoarticular lesions. This disease rarely involves the temporomandibular joint (TMJ). Although it is a disease with a good long-term prognosis, its treatment remains challenging. We describe a case with long-term follow-up of SAPHO syndrome for 15 years in which TMJ pain and trismus led to the diagnosis. A 30-year-old woman with TMJ pain and trismus was referred to our department. Her medical history included palmoplantar pustulosis. Sterile inflammation in the left TMJ and diffuse sclerosing osteomyelitis of the mandible were observed. Thus, she was diagnosed with SAPHO syndrome. The symptoms of severe TMJ pain, trismus, and left cheek swelling presented three times in the 15 years. Symptomatic treatment with nonsteroidal anti-inflammatory drugs, antibiotics, corticosteroids, and bisphosphonates was administered several times. There has been no relapse of symptoms over the past nine years. The patient must be continuously kept under observation to look for the relapse of symptoms.
Abnormal Congenital Location of Stapes' Superstructure: Clinical and Embryological Implications
Authors: Vânia Henriques, Rafaela Teles, Ana Sousa, Roberto Estevão, Jorge Rodrigues, Alexandra Gomes, Francisco Silva, Ângelo Fernandes, Fausto Fernandes
Journal: Case Rep Otolaryngol (2016)

Congenital middle ear malformations are rare. Most part of them are usually associated with other malformations, such as aural atresia, microtia, and dysmorphic craniofacial features. A clinical case of a 24-year-old male with a right-sided conductive hearing loss since his childhood, without craniofacial malformation, is presented. He was proposed for exploratory tympanotomy under the suspicious diagnosis of otosclerosis. The surgery revealed an abnormal location of stapes' superstructure, which was attached to the promontory and had an isolated and mobile osseous footplate in the oval window. A stapes prosthesis was inserted and resulted in closure of the air-bone gap by 25 dB. A review of the literature was also performed using MEDLINE. Two theories diverge on the embryologic origin of the stapes. Our findings seem to be in favour of the theory that defines two different embryologic origins to the stapes.
Solitary, adult-onset, intraosseous myofibroma of the rib: a case report and literature review
Authors: Anne Weidlich, Jessica Pablik, Klaus-Dieter Schaser, Doreen Winkler, Elisabeth Mehnert, Hagen Fritzsche
Journal: SAGE Open Med Case Rep (2023)
Keywords: myofibroma, adult-onset, chest, intraosseous, rib, solitary
MeSH terms: Case Reports

Myofibromas are rare benign tumors with myofibroblastic origin. They occur especially in cutis and subcutaneous tissue of the head and the neck, less frequently on the extremities. Myofibromas grow very slowly and are often painless, which is why patients often present relatively late. In the literature, there were many reports about intraosseous myofibromas of the craniofascial bones but reports of the trunk and extremities in adults are very rare. The authors present a very rare case of an intraosseous myofibroma of the ribs resulting in pathological fracture, including a research of literature from other cases of intraosseous myofibromas of the trunk or extremities.
It Is Always Early with Point-of-Care Ultrasound
Authors: Zouheir Ibrahim Bitar, Tamer Mohamed Zaalouk, Ossama Sajeh Maadarani, Ragab Desouky Elshabasy
Journal: Case Rep Crit Care (2020)
MeSH terms: Case Reports

A 56-year-old male was admitted to the emergency department for acute pulmonary edema and septic shock, yet no clear source of infection was noted upon physical examination. Due to his unstable condition, bedside ultrasound was performed. A heterogeneous mass in the liver was noted; hence, a tentative diagnosis of liver abscess was made. The abscess was confirmed by abdominal magnetic resonance imaging. Drainage of the abscess was attempted and guided by early ultrasound. This case highlights that point-of-care ultrasound, when performed by an ultrasound-capable critical care physician, can significantly decrease the time to diagnosis for septic patients.
Analysis of a Cementless Femoral Stem Neck Fracture Using Scanning Electron Microscopy and the Finite Element Method
Authors: Hirokazu Takai, Daisuke Nakayama, Masatoshi Murayama, Tomoki Takahashi
Journal: Case Rep Orthop (2019)
MeSH terms: Case Reports

Implant fracture is one of the rarest complications of total hip arthroplasty (THA). A 57-year-old woman experienced a fracture of the femoral stem (AHFIX Q, KYOCERA, Japan) about five years after THA. We examined the broken stem by digital microscopy, scanning electron microscopy, and finite element method. The anterolateral corner of the stem's neck was found to be the origin point of the fracture. Finite element method analysis revealed that the stress concentration was highest in the corner of the hollow for apparatus attachment. The stem's design has been considered one of the risk factors for stem fracture. In this patient, multiple risk factors, including thin stem (the smallest size, NAR #1), use of the long neck (+3 mm), obesity (body mass index: 27.3), and adjacent osteoarthritis (contralateral THA loosening and knee osteoarthritis), were present. To our knowledge, this is the first reported case of an AHFIX Q stem fracture. Surgeons must keep in mind that fracture of the femoral stem in patients with several risk factors is possible even several years after THA.
A Case Series of Psychological Stress Evaluation as a Risk Factor for Oral Lichen Planus
Authors: Irna Sufiawati, Ani Megawati, Muhammad Al Farisyi, I Nyoman Gede Juwita Putra
Journal: Case Rep Dent (2022)
MeSH terms: Case Reports

Introduction:
Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa with unknown etiology. Suggested predisposing factors for the development of OLP include genetic factors, viral infections, psychological stress, trauma, drug intake, and some systemic diseases. This serial case aimed to evaluate the psychological stress in triggering various types of OLP and its management. Case Report. Six patients, four females and two males with an age range from 23 to 57 years, came to an oral medicine clinic with chief complaints of chronic pain and burning sensations in the oral cavity. All cases showed typical clinical features of OLP on the oral mucosa, including reticular, plaque-like, erosive, and ulcerative lesions. An incisional biopsy was performed in some cases and the histopathology features confirmed the diagnosis of OLP with no signs of dysplasia/malignancy. According to the Depression, Anxiety, Stress Scale (DASS)-21, the patients had different levels of depression ranging from mild to severe; 3 patients were considered to have moderate anxiety and others had severe anxiety; and 5 patients experienced mild stress and 1 patient had moderate stress. The patients were given corticosteroids, supportive therapy, and psychological counseling. All patients experienced significant improvement of the lesions after treatment.
Conclusion:
Psychological stressors play an essential role as a risk factor in the development of OLP. Therefore, management of OLP encompasses not only an appropriate treatment of the lesions but also psychological intervention.
Management of pneumothorax in the setting of chronic non-invasive positive pressure ventilation: A case series
Authors: Avnee J Kumar, Alexander Hjelmaas, Benjamin H Singer
Journal: Respir Med Case Rep (2022)
Keywords: muscular dystrophy, non-invasive ventilation, pneumothorax
MeSH terms: Case Reports

There is a growing population of patients who require chronic noninvasive ventilation. While these patients often have no parenchymal lung disease, the use of positive pressure ventilation itself predisposes to both initial and recurrent pneumothoraces. Furthermore, generally accepted pneumothorax management strategies, such as removing a chest tube after liberation from positive pressure ventilation, are not possible in this population. Despite this, there is a lack of clear guidance on management of pneumothorax in the chronically ventilated patient. In this case series, we discuss the management of pneumothoraces in patients requiring chronic noninvasive mechanical ventilation in our Assisted Ventilation Clinic (AVC). Our experience suggests a potential role of definitive treatment of the initial pneumothorax to prevent reoccurrence.
The Elusive SLIPPERS Syndrome (Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids): A Case Report and Literature Review
Authors: Adnan Khan, Muhammad Mohsin Khan, Issam A Al-Bozom, Younis Baregzai, Wanis Ibrahim, Firas Hammadi
Journal: Int Med Case Rep J (2023)
Keywords: clippers, slippers, corticosteroids, neuroinflammation, perivascular infiltration
MeSH terms: Case Reports

Background:
In 2015, the term "SLIPPERS" was created to refer to a rare type of encephalomyelitis called CLIPPERS syndrome that affects the pons and sometimes other nearby structures, but in this case, it primarily affects the supratentorial region. This variation of the condition is responsive to treatment with steroids.
Case description:
We report the case of a patient who presented with seizures and visual field deficit and had typical radiological and histopathological characteristics of SLIPPERS syndrome.
Conclusion:
Although the literature is inundated with CLIPPERS syndrome, its supratentorial variant is extremely rare. To our knowledge, this is fourth case of SLIPPERS syndrome to be reported in literature and serves to enhance clinicopathological understanding of this elusive entity.
Spontaneous subserosal venous rupture overlying a uterine leiomyoma in a young woman
Authors: Amel Achour Jenayah, Sarah Saoudi, Nour Sferi, Rim Skander, Sofiène Ben Marzouk, Abdallah Cherni, Ezzeddine Sfar, Dalenda Chelli, Fethia Boudaya
Journal: Pan Afr Med J (2017)
Keywords: hemoperitoneum, gynaecological emergency, leiomyoma
MeSH terms: Hemoperitoneum / etiology, Leiomyoma / diagnosis, Uterine Neoplasms / diagnosis, Case Reports, Adult, Diagnosis, Differential, Female, Humans, Leiomyoma / complications, Leiomyoma / pathology, Rupture, Spontaneous, Uterine Neoplasms / complications, Uterine Neoplasms / pathology

Uterine leiomyomas are very common tumors found in women. Rupture of veins on the surface of uterine leiomyoma is an unusual source of hemoperitoneum. It is an extremely uncommon gynaecological cause of hemoperitoneum. It is a life threatening emergency. We report a case of massive intraperitoneal hemorrhage due to rupture of vessels on the surface of subserous leiomyoma. A differential diagnosis of rupture of leiomyoma'ssurface vessel should be considered, while dealing with a case of hemoperitoneum with pelvic mass.
Stonefish envenomation of hand with impending compartment syndrome
Authors: Terence Khai Wei Tay, Han Zhe Chan, Tunku Sara Tunku Ahmad, Kok Kheng Teh, Tze Hau Low, Nuraliza Ab Wahab
Journal: J Occup Med Toxicol (2016)
Keywords: bites and stings, impending compartment syndrome, marine toxins, stonefish, synanceia
MeSH terms: Case Reports

Background:
Marine stings and envenomation are fairly common in Malaysia. Possible contact to various marine life occurs during diving, fishing and food handling. Even though majority of fish stings are benign, there are several venomous species such as puffer fish, scorpion fish, lionfish, stingray and stonefish that require urgent medical treatment. Stonefish is one of the most venomous fish in the world with potential fatal local and systemic toxicity effects to human.
Case presentation:
We reported a case of stonefish sting complicated with impending compartment syndrome.
Conclusions:
Medical staff should be alert about the possibility of this potential emergency in standard management of stonefish stings.