OpenMed/multicare-articles huggingface dataset:
Retrograde intrarenal surgery with intelligent control of renal pelvic pressure for staghorn calculi: a case report
Authors: Xiaolong He, Xin Huang, Qiliang Zhai, Leming Song, Xiaolin Deng
Journal: Front Med (Lausanne) (2024)
Keywords: case report, intelligent control, renal pelvic pressure, retrograde intrarenal surgery, staghorn calculi
MeSH terms: Case Reports

Percutaneous nephrolithotomy is the gold standard treatment for staghorn calculi. However, this study reviews a case of an almost complete removal of staghorn calculi following one session of retrograde intrarenal surgery with intelligent control of renal pelvic pressure (RIRS-ICP). A 45 years-old female patient with an 8.3 × 4.5 cm complete staghorn stone was infected with Proteus mirabilis. Two sensitive antibiotics, piperacillin tazobactam and etimicin, were administered for 3 days. Semirigid 7/8.4 Fr ureteroscope was used to treat the renal pelvis and upper calyceal calculi for 57 min. A 550 μm holmium laser fiber with 2.0 J × 30 Hz was set. Next, a disposable flexible ureteroscope of 8.4 Fr was used to address residual middle and lower calyx stones for 94 min. A 200 μm holmium laser fiber with 1.0 J × 30 Hz was set. The renal pelvis pressure was controlled within 15 mmHg. A 2 mm CT scan on the first postoperative day showed inferior caliceal residue of approximately 1.0 × 0.6 cm. No complications occurred. This suggests that RIRS-ICP is a safe and effective treatment for staghorn calculi.
Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary Planning
Authors: Brenna Cook, Caroline Shadowen, Lorna Clark, Alena Hoover, Stephanie Lee, Whitney Bender
Journal: Case Rep Infect Dis (2024)
MeSH terms: Case Reports

Introduction:
Herpes simplex (HSV) and varicella zoster (VZV) viruses are harmful infectious agents in pregnancy due to their ability to impact maternal-fetal dyads through various modalities including vertical transmission, neonatal infection, and maternal morbidity. As a result, accurate diagnosis and prompt treatment of these infections in pregnancy is critical.
Case:
A 19-year-old primigravida presented to our tertiary care center at 30 weeks' gestation with vulvar swelling, burning, and pain. Workup included direct PCR testing of a particularly erythematous area of the vulva which returned positive for VZV. The patient was treated with a 10-day course of acyclovir with resolution of her symptoms. She later had a full-term spontaneous vaginal delivery outside of the infectious window with no significant morbidity for either her or her neonate.
Conclusion:
Although a rare presentation, the presence of a genital lesion or labial swelling during pregnancy warrants workup for VZV, particularly among patients known to be varicella nonimmune. If genital VZV is diagnosed during pregnancy, the development of contingency plans through interdisciplinary collaboration should be pursued to ensure a safe delivery and postpartum course for both the maternal-fetal dyad as well as other patients on the unit and the provider care team.
Case Report: The application of amplatzer vascular plug to repair aortic dissection intimal tears and false lumen
Authors: Ruihua Li, Yang Liu, Jianjun Jiang
Journal: Front Cardiovasc Med (2024)
Keywords: amplatzer vascular plug, aortic dissection, coils, embolization technique, endovascular treatment
MeSH terms: Case Reports

In recent years, significant advancements have been made in endovascular therapy for aortic dissection, resulting in the development of various treatment methods. Nevertheless, there is a contentious discussion regarding the suitability of different treatment methods for addressing the unique features of individual lesions. Specifically, the matter of whether the presence of small intimal tears or multiple distal tears requires extensive aortic coverage with graft stents, which may block the blood supply to important organs, intercostal arteries, or lumbar arteries, remains unresolved. Further research is necessary to determine the need for complex fenestrated or branched endovascular aortic repair (F/B-EVAR) in the management of chronic post-dissection aneurysms involving visceral arteries. Our report highlights the successful endovascular repair of three patients with aortic dissection, encompassing one Stanford A type and two Stanford B types. Utilizing the Amplatzer Vascular Plug (AVP) alone or in combination with the coil embolization technique, we achieved favorable clinical outcomes. This article aims to provide valuable insights and new perspectives on the tailored management of aortic dissection by conducting a comprehensive examination of the subtle differences in the treatment processes and techniques applied to these three patients.
Case Report: Persistent left superior vena cava: an incidental finding during peripherally inserted central catheter placement
Authors: Shi-Xiang Pan, Ye-Ling Zhang, Fang Fang
Journal: Front Surg (2024)
Keywords: ecg, chemotherapy, enhanced ct, peripherally inserted central catheter, persistent left superior vena cava
MeSH terms: Case Reports

Background:
A peripherally inserted central catheter (PICC) is a specialized type of long-term intravenous catheter commonly employed for administering chemotherapy. The operation and management of PICC should exclusively be carried out by trained healthcare professionals equipped with the requisite knowledge of anatomy, procedural technique and patient care. Persistent left superior vena cava (PLSVC) is a vascular malformation which is typically asymptomatic in clinical presentation, almost always identified during invasive surgery or imaging examinations.
Case presentation:
Herein, we detailed a case involving a breast cancer patient whose PLSVC was identified during the placement of PICC because of the negative P-wave in electrocardiogram (ECG). Subsequent examination, including chest x-ray imaging, postoperative enhanced CT of the chest, ECG, and consultation with an experienced imaging physician confirmed that the patient's variant type was PLSVC type I. 2160. Removal of the catheter was deemed unnecessary, as the catheter tip was appropriately positioned and no other concomitant cardiovascular malformations were detected.
Conclusion:
The PLSVC is a vascular anomaly and is relatively uncommon within the general population. The operator should possess a thorough familiarity with the potential anatomical variations of left superior vena cava, and specialized case profile should be established for patients diagnosed with PLSVC.
Oro-Pharyngeal Candidiasis in Two Dengue Patients
Authors: Drupad Das, Shiv N Sahu, Prasan K Panda, Madhusmita Panda
Journal: Cureus (2024)
Keywords: dengue hemorrhagic fever (dhf), hyperglycemia, mutant era, oral candidiasis, oral thrush
MeSH terms: Case Reports

Dengue, a prevalent arboviral disease, has witnessed a resurgence in India, with outbreaks frequently reported. However, dengue-associated oral (oro-pharyngeal) candidiasis (DAOC) was never reported. We present two severe dengue cases with oral/oro-pharyngeal pseudomembranous candidiasis. Case 1 of a young man without any comorbidities or abuse or immunosuppression presented with fever, headache, altered sensorium, throat pain on recovery, and laboratory reports confirmed dengue with leukopenia, thrombocytopenia, and severe hepatic involvement with oro-pharyngeal candidiasis. Similarly, case 2 of a middle-aged man with a history of smoking and diabetes presented with fever, gum bleeding, and throat pain, later confirmed to be dengue NS1 positive with thrombocytopenia, and mild-moderate hepatic involvement along with oral-oro-pharyngeal candidiasis. Both cases showed improvement with conservative management and oral nystatin suspension. These cases prompt consideration of superadded candida infections in dengue patients, emphasizing the need for further study and clinical vigilance.
Medial Patellofemoral Ligament Reconstruction: A Case Report for an Integrated Rehabilitation Approach
Authors: Abhishek Gujar, Pratik R Jaiswal, Swapnil U Ramteke
Journal: Cureus (2024)
Keywords: arthroscopic repair, excercise and weight training, medial patellofemoral ligament, physical therapy rehabilitation, sports physiotherapy
MeSH terms: Case Reports

Medial patellofemoral ligament (MPFL) reconstruction is a surgical treatment, primarily indicated for patients grappling with recurrent patellar instability stemming from traumatic injury or underlying anatomical anomalies. This abstract aims to elucidate the indispensable role of physiotherapy in the post-operative rehabilitation trajectory for individuals subjected to MPFL reconstruction. Physiotherapy emerges as a linchpin in securing a triumphant outcome, fostering the healing of patellar stability, augmentation of range of motion (ROM), and bolstering muscular strength while concurrently mitigating potential complications. The abstract accentuates salient facets of a physiotherapeutic regimen, encompassing prompt post-operative mobilization, meticulously tailored exercise paradigms, adept utilization of manual therapy modalities, and comprehensive patient education. Notably, this collaborative endeavor between orthopedic surgeons and physiotherapists is pivotal in optimizing patient convalescence, restoring them to their pre-injury functional acumen. A paramount emphasis is placed on individualized rehabilitation strategies, gradual and systematic exercise protocols, and patient adherence, thereby underscoring how the harmonious synergy between surgical and physiotherapeutic interventions augments the prospects of achieving a successful MPFL reconstruction outcome.
Intrahepatic cholangiocarcinoma detected on 18F-PSMA-1007 PET/MR imaging in a prostate cancer patient: a case report and literature review
Authors: Yu Sun, Haiyan Wang, Yihong Yang, Zhiwen You, Jun Zhao
Journal: Front Oncol (2024)
Keywords: hepatocellular carcinoma, intrahepatic cholangiocarcinoma, positron emission topography, prostate cancer, prostate-specific membrane antigen
MeSH terms: Case Reports

Radionuclide probes-targeted prostate-specific membrane antigen (PSMA) is used in diagnosis and treatment of prostate cancer (PCa). Recent studies have shown that PSMA is expressed in the tumor neovascular endothelium, such as in malignant liver tumors. We report a case of PCa with incidental intrahepatic cholangiocarcinoma (ICC) detection using 18F-PSMA-1007 and 18F-fluorodeoxyglucose (FDG) positron emission topography (PET)/MRI.18F-PSMA-1007 PET/MRI of our patient with PCa showed that one liver lesion had high PSMA uptake. 18F-FDG PET/MRI revealed minimal FDG uptake in the liver lesion. Histopathological examination revealed that the liver lesion was moderately to poorly differentiated cholangiocarcinoma. Our studies, along with others, demonstrated that malignant liver tumors, such as ICC, hepatocellular carcinoma (HCC), and combined hepatocellular-cholangiocarcinoma (CHC), and benign lesions, such as benign liver hemangioma, focal nodular hyperplasia, focal inflammation and steatosis, vascular malformation, and fatty sparing, exhibited elevated PSMA uptake. Moreover, PSMA-PET was superior to FDG-PET in detecting ICC and HCC, indicating that PSMA-PET may be used as alternative staging and to identify patients for PSMA-targeted therapy.
Infective Endocarditis Due to Serratia odorifera: A Case Report and Literature Review
Authors: Muhammad Hussain, Bereket Tewoldemedhin, Muhammad Waqas, Fnu Marium, Nardos Tewoldemedhin, Siham Hussien, Miriam Michael, Jihad Slim
Journal: Cureus (2024)
Keywords: av graft, hemodialysis, infective endocarditis, odorifera, serratia, transesophageal echocardiography (tee)
MeSH terms: Case Reports

Serratia odorifera from the time of its discovery in the 1970's had been considered a common colonizer of the skin with little pathogenic potential. Cases of human infections caused by S. odorifera are relatively rare. To date, very few cases have been reported describing primarily bloodstream and urinary tract infections. We describe a patient who developed endocarditis due to S. odorifera confirmed with a transesophageal echocardiogram. The patient was treated with six weeks of antibiotics with uneventful recovery. After a thorough review of published literature, we concluded that this is the first case of endocarditis caused by S. odorifera reported in English literature.
Reintroduction of Clozapine following Neuroleptic Malignant Syndrome in a Young Patient with Resistant Schizophrenia
Authors: Miriam Chandad, Rajae Chlihfane, Safae Kodad, Bouchra Oneib, Fatima Elghazouani
Journal: Case Rep Psychiatry (2024)
MeSH terms: Case Reports

The incidence of neuroleptic malignant syndrome justifies the immediate discontinuation of the drug in question and the reinstitution of therapy with another drug. In the case of resistant schizophrenia treated with clozapine, there are insufficient therapeutic options. We report the case of a young patient followed up for resistant schizophrenia who developed neuroleptic malignant syndrome after 5 years of therapy with clozapine. Clozapine therapy was successfully reinitiated, and the dosage was increased to 300 mg/day over 62 days. In light of this clinical case and a review of the literature, we report the possibility of reintroducing clozapine following an incidence of malignant syndrome in patients with resistant schizophrenia with respect to certain rules; in particular, a slow increase in dose after a reasonable period of time and close monitoring.
Pemphigus Foliaceus after COVID-19 Vaccination: A Report of Two Cases
Authors: Nguyen Nhat Pham, Thuy Thi Phan Nguyen, Thao Thi Phuong Vu, Hao Trong Nguyen
Journal: Case Rep Dermatol Med (2023)
MeSH terms: Case Reports

Autoimmune bullous diseases (AIBDs) following coronavirus disease (COVID-19) vaccination have been previously documented in medical literature, given the comparable nature of the RNA antigen in these vaccines to that of the cellular nuclear matter. However, pemphigus foliaceus has been reported less frequently than other postimmunization AIBDs worldwide. Two women were admitted to our hospital with skin erosion over their faces, trunks, and extremities after receiving COVID-19 vaccination. Upon examination and consultation with pathologists, the diagnosis of pemphigus foliaceus was confirmed for both patients. In an effort to contribute to the knowledge on this intriguing topic, we present these two aforementioned cases of pemphigus foliaceus following COVID-19 vaccination, which may initially appear as a typical occurrence but exhibit some noteworthy characteristics.
The Noble Suicide: The Case of a Self-Contained Dagger in the Heart and a Literal Raw
Authors: Maricla Marrone, Benedetta Pia De Luca, Marco Papalino, Fortunato Pititto, Carlo Angeletti, Roberto Bellacicco, Michela Raino, Giuseppe Pulin, Francesca Tarantino
Journal: Case Rep Psychiatry (2024)
MeSH terms: Case Reports

According to WHO estimates, more than 700,000 people die each year due to suicide and suicides performed with a bladed weapon account for approximately 1.6%-3% of all suicides. It is statistically more common to find injuries to the heart, lungs, and thoracic vessels in homicides, whereas in suicides there is a higher frequency of vascular injuries to the extremities of the limbs. Also in suicides, the presence of "hesitation marks," related to the attempts the victim makes before having the courage to kill himself, can often be found. In the case presented by the authors, these parameters are subverted: There was only one injury and it was the fatal one, it was located on the chest and reached the heart. But it was suicide. The circumstantial data, the psychological explanation, and the previous similar suicide attempt left no doubt about it. The man decided to commit suicide because he could no longer find meaning in his life after losing hope for a career as a pianist, having been diagnosed with a degenerative disease in his hands. The man hated himself and his existence: The future appeared extremely negative and the only escape was self-suppression. This case report makes an essential contribution to the already existing Literature as it shows a suicide that occurred in an unusual manner.
Open Capsular Repair with Dermal allograft and tarsal tunnel release in the treatment of Tarsal Tunnel Syndrome in a Young Collegiate Athlete: A Case Report
Authors: Bryan N Ubanwa, Chimobi C Emukah, David M Heath, Marie T Chapentier, Robert O Cone, Kenneth Kenneth-Nwosa, Katherine C Bartush
Journal: SAGE Open Med Case Rep (2024)
Keywords: ankle, foot, orthopedics/rehabilitation/occupational therapy, sports medicine, tarsal tunnel
MeSH terms: Case Reports

Tarsal tunnel syndrome is an entrapment neuropathy of the posterior tibial nerve beneath the flexor retinaculum that can be precipitated by either intrinsic or extrinsic factors. We report a unique case of a posterior medial ankle joint capsular defect with localized fluid extravasation between the flexor digitorum longus and flexor hallucis longus leading to symptoms consistent with tarsal tunnel syndrome in a collegiate tennis player. This patient is a 19-year-old female with no past medical history who presented with symptoms consistent with tarsal tunnel syndrome. After confirmation with magnetic resonance imaging, the patient underwent capsular reconstruction with dermal allograft in combination with a tarsal tunnel release. The patient had improvement in pain and recovery of paresthesia 3 months postoperatively. At the latest follow-up of 1 year postoperatively, the patient has not had a recurrence of symptoms and has returned to the same level of competitive play. Many different causes of tarsal tunnel syndrome are described in the literature, but to our knowledge, there is no current literature that describes a defect in the tibiotalar joint capsule as a cause of tarsal tunnel syndrome.
Haemophilus influenzae blood-stream infection and third-generation cephalosporin susceptibility testing: a comparative case study using EUCAST and CLSI guidelines
Authors: John Merlino, Sophia Rizzo, Suzanne English, Sai Rupa Baskar, Steven Siarakas, Genevieve Mckew, Shelanah Fernanado, Timothy Gray
Journal: Access Microbiol (2023)
Keywords: blnar, clsi, eucast, haemophilus influenzae, cefotaxime, ceftriaxone, resistance, susceptibility
MeSH terms: Case Reports

Introduction:
In this comparative case study, we discuss clinically relevant discrepancies of antimicrobial susceptibility testing (AST) interpretation for ceftriaxone against a non-typable, beta-lactamase negative, ampicillin-resistant (BLNAR) Haemophilus influenzae isolated from a blood culture.
Case report:
A 74-year-old man presented with a 3 day illness characterized by shortness of breath and dry cough, and was noted to be febrile and hypoxic on admission. A blood culture bottle flagged positive with Gram-negative coccobacilli, later identified as Haemophilus influenzae with the patient commenced on ceftriaxone. The isolate was beta-lactamase negative and antibiotic susceptibility testing (AST) using disc diffusion revealed the isolate resistant to ceftriaxone and ampicillin by EUCAST methodology, with the patient subsequently changed to amoxicillin/clavulanate. Further AST using the CLSI methodology in parallel demonstrated discrepant results between the two susceptibility methods. The patient recovered without complications.
Conclusion:
This discrepancy could lead to inconsistent reporting of susceptibilities between laboratories, and consequently antibiotic prescribing, especially for invasive isolates. As more laboratories adopt EUCAST methodologies for AST interpretation in Australia and globally, it is important for clinicians to consider the clinical implications of these methodological discrepancies.
Transitioning from junior to senior: a case study on elite judokas in South Korea
Authors: Hee Jung Hong, Seung Han Hong
Journal: Front Psychol (2023)
Keywords: athletes’ career development, athletes’ career transition, judo, junior-to-senior transition, student-athletes

Introduction:
This study explores the experiences of Korean elite judokas during their junior to senior transition (JST), including both male and female participants, to provide empirical evidence for the development of tailored support services or programs for this target population.
Methods:
We recruited 12 elite judokas for our study, comprising eight males and four females, all in their first year of university. Given their preferences and availability at the time of data collection, participants were divided into three focus groups: Focus Group 1 (FG1; four male participants), Focus Group 2 (FG2; four female participants), and Focus Group 3 (FG3; four male participants). Thematic analysis was applied to analyze the data from the focus group interviews.
Results:
Five main themes were identified: (a) COVID-19-Induced Frustration, (b) From Big Fish in a Small Pond to Small Fish in a Big Pond, (c) Challenges in Academic Commitment, (d) Adapting to Transitions in Living Arrangements, and (e) Recognizing Support Needs for the JST.
Discussion:
The findings of this study provide both theoretical and practical implications that could improve judokas' experiences during the challenging physical and mental phase of JST, as well as inform the establishment of tailored support programs and schemes for successful and smooth JSTs for athletes.
Case report: Improvement of gait with adaptive deep brain stimulation in a patient with Parkinson's disease
Authors: Ioannis U Isaias, Laura Caffi, Linda Borellini, Antonella M Ampollini, Marco Locatelli, Gianni Pezzoli, Alberto Mazzoni, Chiara Palmisano
Journal: Front Bioeng Biotechnol (2024)
Keywords: parkinson’s disease, adaptive deep brain stimulation, gait, local field potentials, subthalamic nucleus
MeSH terms: Case Reports

Gait disturbance is a common and severe symptom of Parkinson's disease that severely impairs quality of life. Current treatments provide only partial benefits with wide variability in outcomes. Also, deep brain stimulation of the subthalamic nucleus (STN-DBS), a mainstay treatment for bradykinetic-rigid symptoms and parkinsonian tremor, is poorly effective on gait. We applied a novel DBS paradigm, adjusting the current amplitude linearly with respect to subthalamic beta power (adaptive DBS), in one parkinsonian patient with gait impairment and chronically stimulated with conventional DBS. We studied the kinematics of gait and gait initiation (anticipatory postural adjustments) as well as subthalamic beta oscillations with both conventional and adaptive DBS. With adaptive DBS, the patient showed a consistent and long-lasting improvement in walking while retaining benefits on other disease-related symptoms. We suggest that adaptive DBS can benefit gait in Parkinson's disease possibly by avoiding overstimulation and dysfunctional entrainment of the supraspinal locomotor network.
Nothing Great Comes Without Its Risks: A Rare Case of Pembrolizumab-Induced Hypophysitis
Authors: Ashen Fernando, Aastha Mittal, Rashid Cheema
Journal: JCEM Case Rep (2023)
Keywords: hypophysitis, immune check point inhibitors, immune-related adverse effects, pembrolizumab
MeSH terms: Case Reports

Pembrolizumab is an immune checkpoint inhibitor that targets the programmed cell death protein 1 and enhances immune activity against cancer cells. This has emerged as a powerful tool in the treatment of cancer in patients with severe metastatic disease. Despite this, immune checkpoint inhibitors are associated with many immune-related adverse effects. Reported endocrinopathies include thyroid dysfunction, insulin-deficient diabetes mellitus, primary adrenal insufficiency, and hypophysitis. Hypophysitis is more commonly associated with cytotoxic T-lymphocyte associated antigen 4 inhibitors like ipilimumab and rarely with pembrolizumab. A high clinical suspicion is needed to pursue a diagnosis of immune checkpoint inhibitorinduced hypophysitis, and prompt diagnosis is of immense importance due to the potentially life-threatening nature of endocrinopathies. We present a case of a 64-year-old Caucasian male individual undergoing treatment with pembrolizumab for undifferentiated lung carcinoma who subsequently developed hypophysitis.