OpenMed/multicare-articles huggingface dataset:
A 17-year-old female with systemic lupus presents with complex movement disorder: possible relationship with antiribosomal p antibodies
Authors: Muhammed Emin Ozcan, Meriç Adil Altınöz, Hasan Hüseyin Karadeli, Talip Asil, Abdulkadir Koçer
Journal: Case Rep Neurol Med (2013)

Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation with movement disorder was not previously established. Our case report involves a 17-year-old Caucasian female patient positive for only antiribosomal P antibody and lupus anticoagulant who presented with a sudden onset of complex movement disorder. After complete cessation of physical signs with olanzapine, anticardiolipin and anti- β 2 glycoprotein I antibodies became positive which indicates a likely discordance between movement disorder and antiphospholipid antibodies. This also indicates a potential causal role of antiribosomal P antibodies in inducing movement disorder.
Congenital lobar emphysema: a case report
Authors: Asok Kumar Datta, Syamali Mandal, Jadab Kumar Jana
Journal: Cases J (2009)

Congenital lobar emphysema is a rare variety of congenital malformation of lung characterized by over distension of a lobe of a lung due to partial obstruction of the bronchus. We are reporting a neonate admitted in the pediatric emergency ward with the respiratory distress since 16th day of life.Investigation revealed the overexpansion of the left upper lobe with mediastinal herniation, shifting of the mediastinum to the opposite side and collapse of the ipsilateral lower lobe. The baby was treated with conservative treatment and the condition of the baby was improved.
Dietary protein sources and tumoral overexpression of RhoA, VEGF-A and VEGFR2 genes among breast cancer patients
Authors: Ali Shokri, Saeed Pirouzpanah, Mitra Foroutan-Ghaznavi, Vahid Montazeri, Ashraf Fakhrjou, Hojjatollah Nozad-Charoudeh, Gholamreza Tavoosidana
Journal: Genes Nutr (2019)
Keywords: angiogenesis, breast cancer, metastasis, protein, rhoa, vegf-a, vegfr-2

Background:
High protein intake may promote angiogenesis giving support to the development of metastasis according to the experimental data. However, nutritional epidemiologic evidence is inconsistent with metastasis. Therefore, we aimed to study the association between dietary intake of protein and tumoral expression levels of Ras homologous gene family member A (RhoA), vascular endothelial growth factor-A (VEGF-A), and VEGF receptor-2 (VEGFR2) in primary breast cancer (BC) patients.
Methods:
Over this consecutive case series, 177 women primary diagnosed with histopathologically confirmed BC in Tabriz (Iran) were enrolled between May 2011 and November 2016. A validated food frequency questionnaire was completed for eligible participants. Fold change in gene expression was measured using quantitative real-time PCR. Principal component factor analysis (PCA) was used to express dietary groups of proteins.
Results:
Total protein intake was associated with the expression level of VEGF-A in progesterone receptor-positive (PR+: β = 0.296, p < 0.01) and VEGFR2 in patients with involvement of axillary lymph node metastasis (ALNM+: β = 0.295, p < 0.01) when covariates were adjusted. High animal protein intake was correlated with overexpression of RhoA in tumors with estrogen receptor-positive (ER+: β = 0.230, p < 0.05), ALNM+ (β = 0.238, p < 0.05), and vascular invasion (VI+: β = 0.313, p < 0.01). Animal protein intake was correlated with the overexpression of VEGFR2 when tumors were positive for hormonal receptors (ER+: β = 0.299, p < 0.01; PR+: β = 0.296, p < 0.01). Based on the PCA outputs, protein provided by whole meat (white and red meat) was associated inversely with RhoA expression in ALNM+ (β = - 0.253, p < 0.05) and premenopausal women (β = - 0.285, p < 0.01) in adjusted models. Whole meat was correlated with VEGFR2 overexpression in VI+ (β = 0.288, p < 0.05) and premenopausal status (β = 0.300, p < 0.05) in adjusted models. A group composed of dairy products and legumes was correlated with the overexpression of RhoA (β = 0.249, p < 0.05) and VEGF-A (β = 0.297, p < 0.05) in VI+.
Conclusions:
Based on the multivariate findings, the dietary protein could associate with the overexpression of RhoA and VEGF-VEGFR2 in favor of lymphatic and vascular metastasis in BC patients.
Traumatic Radius Pseudoarthrosis in Neurofibromatosis Type 1: All Treatment Options in One Patient
Authors: Çağdaş Pamuk, Ülker Moralar
Journal: Cureus (2023)
Keywords: bone transplantation, microsurgery, neurofibromatosis 1, pseudarthrosis, radius fractures
MeSH terms: Case Reports

Although congenital pseudoarthrosis of the radius is a rare case, it has been reported many times in the literature in the past and it has been shown that it can be associated with neurofibromatosis type 1. However, traumatic radius pseudoarthrosis has never been reported before. In this case report, all treatment options were applied to the same patient over a four-year period and the results were reported. A two-year-old boy had a left radius diaphysis fracture after a simple fall, and bone union could not be achieved despite the application of cast immobilization, internal fixation grafting, and electrical stimulation in an external center. He was admitted to our hospital when he was six years old. A plain X-ray image and computed tomography scan showed that he had radius pseudoarthrosis and also he was diagnosed with neurofibromatosis type 1 on genetic analysis. The patient underwent wide resection of the segment with pseudoarthrosis and free vascularized fibula grafting. Bone union was achieved in the third postoperative month.
Necrotizing Bacterial Myositis as the Initial Presentation of Severe Aplastic Anaemia
Authors: Synne Dragesund Rørvik, Kristoffer Stange Larsen, Lars Helgeland, Håvard Dale, Birgitta Ivarsen, Øystein Bruserud, Tor Henrik Anderson Tvedt
Journal: Case Rep Hematol (2021)
MeSH terms: Case Reports

Introduction:
Necrotizing soft tissue infections are rapidly progressing infections associated with severe inflammation and cytokine release. Early recognition and surgical intervention are key factors to secure survival. The current case presents a patient with multifocal necrotizing soft tissue infection as the initial presentation of severe aplastic anaemia. Case Presentation. A man in his fifties was admitted with septic shock with multiorgan failure and severe pancytopenia, after two days of malaise with high fever and right flank pain. The diagnosis streptococcal necrotizing myositis was significantly delayed due to atypical clinical findings. After initial surgical exploration, the decision was made to defer from surgical debridement due to extensive involvement of several muscle groups, grave pancytopenia, and suspected dismal prognosis. Surprisingly, the patient stabilized after antibiotics and intensive care treatment. Based on severe pancytopenia and hypocellular bone marrow, with no evidence of other bone marrow disorders, the patient was diagnosed with aplastic anaemia. Treatment for aplastic anaemia with antithymocyte globulin, cyclosporine, and eltrombopaq was started, and 2 months later, a partial haematological recovery was observed. The patient could be discharged from hospital without antibiotic treatment.
Conclusions:
This case illustrates the crucial role of a multidisciplinary approach on admission and further during the clinical course. Clinical improvement despite severe neutropenia and stabilization during immunosuppressive therapy suggest that immunological factors modulate clinical course in necrotizing soft tissue infections.
Sinus Floor Elevation with Modified Crestal Approach and Single Loaded Short Implants: A Case Report with 4 Years of Follow-Up
Authors: Michele Perelli, Roberto Abundo, Giuseppe Corrente, Carlo Saccone, Paolo G Arduino
Journal: Case Rep Dent (2017)
MeSH terms: Case Reports

Tooth extraction is usually followed by bone reduction. In the maxillary posterior region, this remodelling combined with sinus pneumatisation and periodontal defects may lead to a reduced basal bone height available for implant placement. Sinus floor elevation can be performed with different surgical techniques. Crestal approach has demonstrated to be effective, less invasive, and associated with a reduced morbidity. This article reports a modified sinus floor elevation by means of rotary, noncutting instruments, addition of xenograft, and 2 short-threaded implant placements. The aim of the study was to evaluate the implant's success and intrasinus radiographical bone gain after 4 years of functional loading. The premolar implant site presented a starting basal bone height of 6 mm, while the molar site was of 2 mm. In the first surgical step, sinus floor elevation was performed mesially and the implant was inserted, and distally only sinus floor elevation was performed. After 6 months, the mesial implant was uncovered and the second implant was inserted; 4 months later, the second fixture was uncovered, and both fixtures were loaded with single provisional screw-retained crowns and later with single screw-retained porcelain fused to metal crowns. Implants integrated successfully, and crestal bone remodelling did not exceed the smooth collar. Bone gain was 3 mm for the mesial implant and more than 5 mm for the distal one.
Intussusception caused by an inverted Meckel's diverticulum: a rare cause of small bowel obstruction in adults
Authors: Mahdi Bouassida, Bilel Feidi, Mechaal Ben Ali, Mohamed Fadhel Chtourou, Marouene Krifa, Selim Sassi, Fathi Chebbi, Mohamed Mongi Mighri, Hassen Touinsi, Sadok Sassi
Journal: Pan Afr Med J (2011)
Keywords: meckel diverticulum, emergency surgery, intestinal obstruction, intussusception, inverted diverticulum
MeSH terms: Intussusception / etiology, Meckel Diverticulum / complications, Case Reports, Abdominal Pain / etiology, Anastomosis, Surgical / methods, Humans, Intestine, Small, Intussusception / pathology, Intussusception / surgery, Male, Vomiting / etiology, Young Adult

Adult intussusception due to Meckel's diverticulum is an uncommon cause of intestinal obstruction. However, the surgeon should still be suspicious of this condition since the non specific symptoms and the rarity of it make a preoperative diagnosis uncertain. Considering the secondary nature of adult intussusception and the necessity of early surgical intervention to avoid morbidity and mortality, we report one case of intussusception due to Meckel's diverticulum in an adult. A 22-year-old patient was admitted to our hospital with vomiting and abdominal pain. The abdomen was hard with tenderness. We diagnosed an acute small bowel obstruction and performed emergency surgery. The intra operative findings were distention of the small bowel and intussusception of ileus due to an inverted Meckel's diverticulum located 70 cm from the ileocecal valve. 30 cm ischemic loop was identified. A segmental small bowel resection and hand-sewn anastomosis was performed. Histopathology distinguished Meckel's diverticulum measuring 5 cm x 3.5 cm x 1 cm and no signs of malignancy.
Bilateral proptosis and bitemporal swelling: A rare manifestation of acute myeloid leukemia
Authors: Dinesh Rajput, Ram Naval, Kamlesh Yadav, Arun Tungaria, Sanjay Behari
Journal: J Pediatr Neurosci (2010)
Keywords: acute myeloid leukemia, bitemporal swelling, chemotherapy, proptosis
MeSH terms: Case Reports

Background:
In Acute Myeloid Leukemia (AML), malignant clones of immature myeloid cells (primarily blasts) proliferate, replace bone marrow, circulate in blood and invade other tissues. The unique presentation of bilateral proptosis and bilateral temporal swelling in AML is being reported.
Case report:
A 6-year-old girl presented with low-grade fever, progressively increasing bitemporal swelling and bilateral proptosis. Contrast Enhanced Computed Tomographic (CECT) images revealed enhancing infiltrates occupying the lateral orbital wall, causing proptosis. The infiltrate extended toward the bilateral temporal fossae beneath the temporalis muscle and extradurally beneath the frontal and temporal bones. A high total leucocytic count with immature and deformed cells and, Fine Needle Aspiration Cytology (FNAC) from the temporal swelling, the bone marrow aspirate and biopsy showing leukemic blast cells confirmed the diagnosis of AML. Chemotherapy brought about remission of the disease.
Conclusions:
To the best of the authors' knowledge, simultaneous presence of both bilateral proptosis and bitemporal swellings have not been previously reported in AML. A peripheral blood smear with bone marrow aspirate and biopsy help in the early detection of AML. Institution of early intervention in this potentially fatal disease is often associated with gratifying survival rates.
Mask-Related Glasses Fogging: A Predisposing Mechanism of Falls during the COVID-19 Pandemic
Authors: John F Dankert, Mandeep S Virk
Journal: Case Rep Orthop (2021)
MeSH terms: Case Reports

Fogging is a relatively infrequent, yet annoying, issue encountered by individuals who wear glasses. With the arrival of COVID-19, glasses fogging is more common due to the ubiquitous use of face masks. Individuals are stuck wrestling between leaving their mask off or trying to navigate their day-to-day lives with fogged glasses and risk falling. We report a case of an olecranon fracture sustained due to reduced visibility secondary to mask-related fogging during the COVID-19 pandemic. The recommendations included here will provide health care providers with the necessary information to educate patients regarding prevention of mask-related glass fogging.
A rare cause of acute urinary retention in women: meatal condyloma accuminata, a case report
Authors: Onder Cinar, Mustafa Suat Bolat, Ekrem Akdeniz, Necmettin Sahinkaya
Journal: Pan Afr Med J (2016)
Keywords: acute urinary retention, condyloma acuminata, female urethra
MeSH terms: Condylomata Acuminata / complications, Urethral Diseases / complications, Urinary Retention / etiology, Case Reports, Acute Disease, Condylomata Acuminata / diagnosis, Female, Humans, Middle Aged, Papillomaviridae / isolation & purification, Urethral Diseases / diagnosis, Urethral Diseases / virology, Urinary Retention / virology

Acute urinary retention in women is a rarely seen phenomenon due to pharmacological, neuromuscular, anatomical, functional and infectious causes. Human papillomaviruses causing condyloma acuminata is one of the rarely reported viral infectious cause of acute urinary retention in case reports. A 45-year-old woman with acute urinary retention was found to have a round solid lesion on external urethral meatus. Histopathological examination revealed as condyloma acuminata. Urethral condyloma can be treated by local excision as an effective method for early improvement of voiding function. Even if the genital condyloma can be locally excised, patients should be referred to the gynecologists for cervical cancer screening.
A case series of therapy-related leukemias: A deadly ricochet
Authors: Ronit Juthani, Ashish Ranjan Singh, Debdatta Basu
Journal: Leuk Res Rep (2023)
Keywords: chemotherapy, myeloid, therapy-leukemia
MeSH terms: Case Reports

Therapy-related leukemias(t-leukemia) are late complications arising from chemotherapy and radiotherapy. t-leukemia have a poor prognosis and are more difficult to treat compared to de novo leukemias. The authors present three cases of t-leukemia seen in our hospital in a three year period and discuss new updates concerning the treatment of t-leukemia.
Multimodality imaging in a late septic infection of aortic graft
Authors: Monika Arzanauskaite, Antanas Jankauskas, Reda Arzanauskiene, Evaldas Keleras
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

A 70-year-old diabetic female patient presented with fatigue, headaches, hallucinations and shivers following a history of sinusitis and ophthalmitis. She had an aortic surgery performed 7 years ago for a stenotic and regurgitant aortic valve with aneurysm of the ascending aorta. Work-up brain MRI revealed septic-embolic encephalitis. Multimodality cardiovascular imaging showed abnormal anterior wall of the ascending aortic graft with vegetation extending into the lumen. Blood culture was only positive for Aggregatibacter actinomycetemcomitans, an uncommon cause of infective endocarditis. During aortic surgery, the intraluminal vegetation with suppurated perigraft tissue was confirmed.
Ingested Metallic Spool: A Rare Cause of Acquired Tracheoesophageal Fistula
Authors: Imran Hashim, Nabila Talat
Journal: APSP J Case Rep (2017)
Keywords: child, foreign body, metallic spool, tracheoesophageal fistula
MeSH terms: Case Reports

Foreign body (FB) ingestion is a common problem in children. Prolonged impaction of FB in esophagus may result in tracheoesophageal fistula (TEF). A 6-year-old girl presented with progressive dysphagia and recurrent chest infections. No history of FB ingestion was given by parents. Further investigations revealed FB (spool) in cervical esophagus. Patient was successfully managed by surgery through trans-cervical approach.
Rescue balloon pulmonary angioplasty for life-threatening acute pulmonary embolism on chronic thromboembolic pulmonary hypertension patients
Authors: Keiko Sumimoto, Yu Taniguchi, Hiroyuki Fujii, Keisuke Miwa, Yoichiro Matsuoka, Yasunori Tsuboi, Noriaki Emoto, Ken-Ichi Hirata
Journal: Respir Med Case Rep (2021)
Keywords: acute pulmonary embolism, chronic thromboembolic pulmonary hypertension, rescue balloon pulmonary angioplasty, veno-arterial extracorporeal membrane oxygenation
MeSH terms: Case Reports

We report the cases of two patients with life-threatening acute pulmonary embolism (PE) on chronic thromboembolic pulmonary hypertension (CTEPH) who were treated with rescue balloon pulmonary angioplasty (BPA). These cases highlight the effect of rescue BPA on acute PE on CTEPH, which requires veno-arterial extracorporeal membrane oxygenation.
Rapidly progressive lung cysts and pleural effusion: a case report
Authors: Diana Olsen, Charlene Molloy, P S Sriram
Journal: Case Rep Pulmonol (2011)
MeSH terms: Case Reports

Angiosarcoma is a rare but highly malignant tumor arising from vascular endothelial cells. Angiosarcoma commonly arises from the heart, liver, breast, and skin including the scalp. Angiosarcoma metastasizing to the lungs can present as either pneumothorax, hemothorax, or pleural effusions. They can rarely present as rapidly enlarging thin-walled pulmonary cysts. A review of the literature is included.
Acute Respiratory Distress Syndrome after Treatment of Metastatic Prostate Cancer with Taxotere: A Case Report and Literature Review
Authors: Ali Raufi, Jennifer Dotson, Mohamad Khasawneh
Journal: Case Rep Urol (2015)

Prostate cancer is the most common cancer in men. Docetaxel is a common chemotherapeutic agent that has proven its efficacy in the treatment of patients with both castration sensitive and resistant metastatic prostate cancer. We report a case of acute respiratory distress syndrome (ARDS) in a patient with metastatic prostate cancer treated with docetaxel (Taxotere). ARDS is very rare but life threatening complication of docetaxel which requires aggressive supportive care and close monitoring. Better awareness and prompt diagnosis of this treatment related ARDS will improve the effectiveness and outcome of its management.
The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients
Authors: Ju Young Bae, Khalil Ian Hussein, Christopher John Howes, John Francis Setaro
Journal: Case Rep Cardiol (2021)
MeSH terms: Case Reports

By July 2021, the United States had over 34.4 million confirmed COVID-19 cases. Various cardiovascular manifestations of COVID-19 have been reported including ST-elevation myocardial infarction (STEMI), and there is concern that SARS-CoV-2 may be associated with a higher thrombus burden. We performed a retrospective chart review of 535 adult patients with COVID-19 admitted at Yale-New Haven Health Greenwich Hospital from February 1, 2020, to May 13, 2020. All admitted patients had undergone testing for serum troponin I and various inflammatory markers, and we identified three patients who were diagnosed with acute STEMI. Data was collected via manual chart review and included patient demographics, comorbidities, laboratory tests, electrocardiogram (ECG) results, echocardiography results, diagnoses during hospitalization, inpatient therapies, and outcomes including length of hospital stay, revascularization results, and mortality. Three of our patients had obstructive coronary artery disease confirmed via angiography. One subject was noted to display vasospasm in addition to coronary atherosclerotic obstruction and refractory thrombus formation. Among our patients with COVID-19 and STEMI, presentations were variable in terms of timing of onset of ECG changes, age, gender, race, comorbidities, symptomology, and outcomes.
Case Report: Opportunities for Treatment of Severe COVID-19 Patients-Lessons From a Death Case
Authors: Yan Wang, Zhuo Niu, Jia-Lin Peng, Hui-Sheng Wang, Ke Zhang
Journal: Front Med (Lausanne) (2020)
Keywords: covid-19, sars-cov-2, rescue, severe, treatment
MeSH terms: Case Reports

With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the incidence of coronavirus disease (COVID-19) increases each day. To date, there is no specific anti-SARS-CoV-2 drug. The usual approach to treating COVID-19 is treating its symptoms. However, this approach is limited by the different conditions of each area. We treated a 57-year-old man who was initially diagnosed with a severe type of the infection, but he progressed to a critical condition and eventually died. We learned valuable lessons from this case. The first lesson is the need to use immediate invasive mechanical ventilation if there is no obvious improvement after using non-invasive ventilation for several hours, which directly affects the prognosis. Another lesson is the risk involved in transferring severe COVID-19 patients. In the process of transfer, various threats may be encountered at any time. Thus, accurate assessment of the patient's condition and strict medical conditions are highly required. During the patient's 25-day treatment, we performed cardiopulmonary resuscitation twice. Currently, many patients require invasive mechanical ventilation and transfer to a superior hospital. We hope our findings will provide some advice and help for treating severe and critical COVID-19 cases.
Primary MALT Type Skin Lymphoma-Is 'Wait and See' a Possible Strategy?
Authors: Florentina Silvia Delli, Thomas Zaraboukas, Ioanna Mandekou-Lefaki
Journal: Clin Med Oncol (2008)
Keywords: malt type, primary cutaneous b-cell lymphoma, therapy
MeSH terms: Case Reports

Primary cutaneous lymphomas are the second most common site of extranodal non-Hodgkin lymphoma. A specifically type named extranodal marginal zone B-cell lymphomas are indolent low-grade neoplasma.We report a case of a 42-year-old white man with multiple subcutaneous tumors located on the trunk and neck. The histopathological exam showed a non-epidermotropic, dense lymphocytic infiltrate. Histologic, immunohistochemical and cytologenetic analysis diagnosed primary cutaneous B-cell lymphoma MALT type. Investigation for other extranodal MALT lymphoma gastrointestinal tract, lung, salivary and thyroid glands was negative. The patient refused radiotherapy, but he accepted every 6 months close follow-up. Over a seven years period, we noticed a progressively disappearance of the skin lesions.The necessity of aggressive treatment of this disease with excellent prognosis is discussed.The treatment necessity of primary cutaneous B-cell lymphoma MALT type is discussed.