OpenMed/multicare-articles huggingface dataset:
Serious invasive Saffold virus infections in children, 2009
Authors: Alex Christian Yde Nielsen, Blenda Böttiger, Jytte Banner, Thomas Hoffmann, Lars Peter Nielsen
Journal: Emerg Infect Dis (2012)
MeSH terms: Cardiovirus / isolation & purification, Cardiovirus Infections / pathology, Central Nervous System Infections / virology, Case Reports, Cardiovirus / classification, Cardiovirus / genetics, Cardiovirus Infections / cerebrospinal fluid, Central Nervous System Infections / pathology, Child, Preschool, Fatal Outcome, Feces / virology, Female, Genome, Viral, Humans, Infant, Male, Phylogeny, Real-Time Polymerase Chain Reaction

The first human virus in the genus Cardiovirus was described in 2007 and named Saffold virus (SAFV). Cardioviruses can cause severe infections of the myocardium and central nervous system in animals, but SAFV has not yet been convincingly associated with disease in humans. To study a possible association between SAFV and infections in the human central nervous system, we designed a real-time PCR for SAFV and tested cerebrospinal fluid (CSF) samples from children <4 years of age. SAFV was detected in 2 children: in the CSF and a fecal sample from 1 child with monosymptomatic ataxia caused by cerebellitis; and in the CSF, blood, and myocardium of another child who died suddenly with no history of illness. Virus from each child was sequenced and shown to be SAFV type 2. These findings demonstrate that SAFV can cause serious invasive infection in children.
Treatment of Laryngoceles: what is the progress over the last two decades?
Authors: Karol Zelenik, Lucia Stanikova, Katarina Smatanova, Michal Cerny, Pavel Kominek
Journal: Biomed Res Int (2014)
MeSH terms: Laryngocele / surgery, Laryngoscopy / methods, Laser Therapy / methods, Robotic Surgical Procedures / methods, Historical Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review, Systematic Review, History, 20th Century, History, 21st Century, Humans, Laryngocele / history, Laryngoscopy / history, Laser Therapy / history, PubMed, Robotic Surgical Procedures / history

Objectives:
To review surgical techniques used in the treatment of laryngoceles over the last two decades and point out developments and trends.
Materials and methods:
PubMed, the Cochrane Library, and the JBI Library of Systematic Reviews were searched using the term "laryngocele." Demographic data, type of laryngocele, presence of a laryngopyocele, type of treatment and need for a tracheotomy were assessed.
Results:
Overall, data on 86 patients were analyzed, culled from 50 articles, of which 41 were case reports and 9 were case series. No single systematic review or meta-analysis or randomized controlled trial has been published on the topic. Altogether, 71 laryngoceles in 63 patients met the criteria for further analysis focusing on surgical treatment. An external approach was selected in 25/29 (86.2%) cases of combined laryngoceles. Microlaryngoscopic resection using a CO2 laser was performed in three cases and endoscopic robotic surgery in one case. The majority of patients with an internal laryngocele, 31/42 (73.8%), were treated using the microlaryngoscopy approach.
Conclusions:
Microlaryngoscopy involving the use of a CO2 laser has become the main therapeutic procedure for the treatment of internal laryngoceles during the past 20 years. An external approach still remains the main therapeutic approach for the treatment of combined laryngoceles.
Childhood pemphigus vulgaris is a challenging diagnosis
Authors: Gastão Tenório Lins, Nathalia Lages Sarmento Barbosa, Eulina Maria Vieira de Abreu, Klinger Vagner Teixeira da Costa, Kelly Chrystine Barbosa Meneses, Rodrigo Neves Silva, Sonia Maria Soares Ferreira
Journal: Autops Case Rep (2021)
Keywords: child, fluorescent antibody technique, direct, pemphigus
MeSH terms: Case Reports

Pemphigus Vulgaris (PV) is an uncommon autoimmune and blistering mucocutaneous disease. Childhood Pemphigus Vulgaris (CPV) is a pediatric variant of PV, which affects children below 12 years, being very rare among children under 10 years of age. CPV has similar clinical, histological, and immunological features as seen in PV in adults. The mucocutaneous clinical presentation is the most common in both age groups. Vesicles and erosions arising from the disease usually cause pain. A few CPV cases have been reported in the literature. This study reports a case of an 8-year-old male patient with oral lesions since the age of 3 years, and the diagnosis of pemphigus was achieved only 2 years after the appearance of the initial lesions. CPV remains a rare disease, making the diagnosis of this clinical case a challenge due to its age of onset and clinical features presented by the patient. Therefore, dentists and physicians should know how to differentiate CPV from other bullous autoimmune diseases more common in childhood.
Epithelial-Myoepithelial Carcinoma of the Breast with Rhabdoid Features
Authors: Karl Grenier, Gulbeyaz Altinel, Zari Dastani, Atilla Omeroglu
Journal: Case Rep Pathol (2020)
MeSH terms: Case Reports

Epithelial-myoepithelial carcinoma of the breast is a rare biphasic tumor composed of intermixed malignant epithelial and myoepithelial components. Myoepithelial cells are known to adopt varied morphologies, including spindle, chondroid, clear cell, and rhabdoid morphologies, and can represent a diagnostic challenge when isolated on biopsy. Rhabdomyosarcoma, phyllodes tumor, metaplastic carcinoma, and myoepithelial carcinoma are primary breast tumors that all have been shown to exhibit rhabdoid features, whether representing true differentiation or morphological mimic. We here report an epithelial-myoepithelial carcinoma of the breast with rhabdoid features in a 76-year-old woman. The rhabdoid-appearing myoepithelial cells are negative for myogenin, consistent with a rhabdoid-like morphology rather than a true rhabdoid differentiation, comparably to previously described myoepithelial carcinoma with rhabdoid features. To our knowledge, this is the first reported case of epithelial-myoepithelial carcinoma of the breast with rhabdoid features and thus adds another entity to the differential diagnosis of breast lesions with rhabdoid features.
Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration
Authors: Akihito Uji, Sotaro Ooto, Masanori Hangai, Shigeta Arichika, Nagahisa Yoshimura
Journal: PLoS One (2013)
MeSH terms: Diagnostic Imaging / methods, Image Enhancement / methods, Ophthalmoscopy / methods, Case Reports, Research Support, Non-U.S. Gov't, Adult, Aged, Eye Diseases / diagnosis, Female, Humans, Image Processing, Computer-Assisted / methods, Male, Middle Aged

Purpose:
To investigate the effect of B-spline-based elastic image registration on adaptive optics scanning laser ophthalmoscopy (AO-SLO)-assisted capillary visualization.
Methods:
AO-SLO videos were acquired from parafoveal areas in the eyes of healthy subjects and patients with various diseases. After nonlinear image registration, the image quality of capillary images constructed from AO-SLO videos using motion contrast enhancement was compared before and after B-spline-based elastic (nonlinear) image registration performed using ImageJ. For objective comparison of image quality, contrast-to-noise ratios (CNRS) for vessel images were calculated. For subjective comparison, experienced ophthalmologists ranked images on a 5-point scale.
Results:
All AO-SLO videos were successfully stabilized by elastic image registration. CNR was significantly higher in capillary images stabilized by elastic image registration than in those stabilized without registration. The average ratio of CNR in images with elastic image registration to CNR in images without elastic image registration was 2.10 ± 1.73, with no significant difference in the ratio between patients and healthy subjects. Improvement of image quality was also supported by expert comparison.
Conclusions:
Use of B-spline-based elastic image registration in AO-SLO-assisted capillary visualization was effective for enhancing image quality both objectively and subjectively.
Utility of cardiac magnetic resonance in assessing right-sided heart failure in sarcoidosis
Authors: Jacob Lønborg, Michael Ward, Anthony Gill, Stuart M Grieve, Gemma A Figtree
Journal: BMC Med Imaging (2013)
MeSH terms: Cardiomyopathies / etiology, Cardiomyopathies / pathology, Magnetic Resonance Imaging, Cine / methods, Sarcoidosis, Pulmonary / complications, Sarcoidosis, Pulmonary / pathology, Ventricular Dysfunction, Right / etiology, Ventricular Dysfunction, Right / pathology, Case Reports, Research Support, Non-U.S. Gov't, Adult, Diagnosis, Differential, Humans, Male

Background:
Cardiac involvement in sarcoidosis is associated with a poor prognosis. In patients with right sided heart failure, differentiating between cor-pulmonale, or cardiac sarcoidosis has important implications to management.
Case presentation:
We present the case of a patient with severe but stable pulmonary sarcoidosis and new onset right sided heart failure despite only mild elevations of pulmonary artery pressure. CMR demonstration of extensive right ventricular fibrosis with associated dilatation and hypokinesis was a key finding for prognosis and management of the patient.
Conclusion:
Cardiac magnetic resonance (CMR) is the preferred investigation in the diagnosis of cardiac sarcoidosis, allowing assessment of myocardial inflammation and fibrosis, as well as function, in a manner not matched by other technologies.
Case Report: Bilateral Deep Brain Stimulation Implantation on Different Targets for a Parkinson's Disease Patient With a Bullet in the Brain
Authors: Yu Tian, Jiaming Wang, Xin Shi, Zhaohai Feng, Lei Jiang, Yujun Hao
Journal: Front Hum Neurosci (2022)
Keywords: parkinson's disease, bullet, case report, deep brain stimulation, different targets
MeSH terms: Case Reports

Patients requiring deep brain stimulation due to intracerebral metallic foreign substances have not been reported elsewhere in the world. Additionally, the long-term effects of metallic foreign bodies on deep brain stimulation (DBS) are unknown. A 79-year-old man with a 5-year history of Parkinson's disease (PD) reported that, 40 years ago, while playing with a pistol, a metallic bullet was accidentally discharged into the left brain through the edge of the left eye, causing no discomfort other than blurry vision in the left eye. DBS was performed due to the short duration of efficacy for oral medication. Because the bullet was on the left subthalamic nucleus (STN) electrode trajectory and the patient's right limb was primarily stiff, the patient received globus pallidus interna (GPi)-DBS implantation in the left hemisphere and STN-DBS implantation in the right hemisphere. During a 6-month postoperative follow-up, the patient's PD symptoms were effectively managed with no noticeable discomfort.
Percutaneous nephrolithotomy for management neglected encrusted ureteral stent in a transplanted kidney: a case report
Authors: Abdul Azis, Syarif Bakri, Muh Zulharyahya Dandy Asmara Putra, Indrawarman Soehardjo
Journal: Pan Afr Med J (2023)
Keywords: urolithiasis, case report, neglected dj stent, percutaneous nephrolithotomy, transplanted kidney
MeSH terms: Nephrolithotomy, Percutaneous, Nephrostomy, Percutaneous / methods, Ureter, Case Reports, Humans, Kidney, Male, Middle Aged, Stents, Tomography, X-Ray Computed

Retrieving these forgotten encrusted double j (DJ) stents could be challenging and require multimodal urological interventions, especially in a single-functioning transplanted kidney. Only a few cases of mini-percutaneous nephrolithotomy (mini-PCNL) via ultrasonography (US) guidance in transplanted kidneys have been published. We report a 47-year-old man; a case of a transplanted kidney, with a complaint of abdominal pain and dysuria for two weeks. The patient had a forgotten DJ stent for more than a year due to a lack of post-procedural follow-up information. An abdominal computed tomography scan showed a 20 x 13mm stone in the proximal tip of the DJ stent. Ultrasonography-guided mini-PCNL with a 19-fr rigid nephroscope was performed without complications. In conclusion, we emphasize the importance of patient education regarding the indwelling DJ stent. This case also provides that if an experienced urologist performs it, the US-guided mini-PCNL is safe and effective in transplanted kidney patients.
SMARCA4-Deficient Carcinoma of Uterine Cervix Resembling SCCOHT-Case Report
Authors: Igor Sirák, Jan Laco, Hana Vošmiková, Loren K Mell, Fernanda G Herrera, Mária Šenkeříková, Milan Vošmik
Journal: Pathol Oncol Res (2021)
Keywords: case report, cervical cancer, diagnostic biomarker, gynecological cancer, high-risk, personalized treatment, predictive marker
MeSH terms: Carcinoma, Small Cell / metabolism, DNA Helicases / deficiency, Hypercalcemia / metabolism, Nuclear Proteins / deficiency, Transcription Factors / deficiency, Uterine Cervical Neoplasms / metabolism, Case Reports, Adolescent, Biomarkers, Tumor / deficiency, Biomarkers, Tumor / genetics, Carcinoma, Small Cell / diagnosis, Carcinoma, Small Cell / genetics, Carcinoma, Small Cell / therapy, DNA Helicases / genetics, Fatal Outcome, Female, Humans, Hypercalcemia / diagnosis, Hypercalcemia / genetics, Hypercalcemia / therapy, Mutation, Nuclear Proteins / genetics, Transcription Factors / genetics, Uterine Cervical Neoplasms / diagnosis, Uterine Cervical Neoplasms / genetics, Uterine Cervical Neoplasms / therapy, Biomarkers, Tumor, Nuclear Proteins, Transcription Factors, SMARCA4 protein, human, DNA Helicases

Small cell carcinoma of hypercalcemic type (SCCOHT) is a rare gynaecological neoplasm, originating mostly in the ovaries. Cervical origin of this very aggressive malignancy with unknown histogenesis is an extremely rare condition, without published management recommendations. Alterations in SMARCA4 gene are supposed to play the major role in SCCOHT oncogenesis and their identification is crucial for the diagnosis. Adequate genetic counselling of the patients and their families seems to be of great importance. Optimal management and treatment approaches are not known yet but may extremely influence the prognosis of young female patients that suffer from this very resistant disease. Nowadays, a translational research seems to be the key for the further diagnostic and treatment strategies of SCCOHT. The purpose of the case report is to provide practical information and useful recommendations on the diagnosis, management, and treatment of SMARCA4-deficient carcinoma of the uterine cervix resembling SCCOHT.
The Close Relationship between Large Bowel and Heart: When a Colonic Perforation Mimics an Acute Myocardial Infarction
Authors: Maria Francesca Secchi, Carlo Torre, Giovanni Dui, Francesco Virdis, Mauro Podda
Journal: Case Rep Surg (2018)
MeSH terms: Case Reports

Colonoscopic perforation is a serious and potentially life-threatening complication of colonoscopy. Its incidence varies in frequency from 0.016% to 0.21% for diagnostic procedures, but may be seen in up to 5% of therapeutic colonoscopies. In case of extraperitoneal perforation, atypical signs and symptoms may develop. The aim of this report is to raise the awareness on the likelihood of rare clinical features of colonoscopic perforation. A 72-year-old male patient with a past medical history of myocardial infarction presented to the emergency department four hours after a screening colonoscopy with polypectomy, complaining of neck pain, retrosternal oppressive chest pain, dyspnea, and rhinolalia. Right chest wall and cervical subcutaneous emphysema, pneumomediastinum, pneumoretroperitoneum, and bilateral subdiaphragmatic free air were reported on the chest and abdominal X-rays. The patient was treated conservatively, with absolute bowel rest, total parental nutrition, and broad-spectrum intravenous antibiotics. Awareness of the potentially unusual clinical manifestations of retroperitoneal perforation following colonoscopy is crucial for the correct diagnosis and prompt management of colonoscopic perforation. Conservative treatment may be appropriate in patients with a properly prepared bowel, hemodynamic stability, and no evidence of peritonitis. Surgical treatment should be considered when abdominal or chest pain worsens, and when a systemic inflammatory response arises during the conservative treatment period.
Outreach services to improve access to health care in South Africa: lessons from three community health worker programmes
Authors: Nonhlanhla Nxumalo, Jane Goudge, Liz Thomas
Journal: Glob Health Action (2013)
Keywords: south africa, access to care, accountability, community health workers, primary health care, social determinants of health
MeSH terms: Community Health Workers / organization & administration, Community-Institutional Relations, Health Services Accessibility / organization & administration, Research Support, Non-U.S. Gov't, Community Health Workers / education, Community Health Workers / standards, Delivery of Health Care / organization & administration, Delivery of Health Care / standards, Health Promotion / organization & administration, Humans, Organizational Case Studies, Organizations / organization & administration, Qualitative Research, South Africa

Introduction:
In South Africa, there are renewed efforts to strengthen primary health care and community health worker (CHW) programmes. This article examines three South African CHW programmes, a small local non-governmental organisation (NGO), a local satellite of a national NGO, and a government-initiated service, that provide a range of services from home-based care, childcare, and health promotion to assist clients in overcoming poverty-related barriers to health care.
Methods:
The comparative case studies, located in Eastern Cape and Gauteng, were investigated using qualitative methods. Thematic analysis was used to identify factors that constrain and enable outreach services to improve access to care.
Results:
The local satellite (of a national NGO), successful in addressing multi-dimensional barriers to care, provided CHWs with continuous training focused on the social determinants of ill-health, regular context-related supervision, and resources such as travel and cell-phone allowances. These workers engaged with, and linked their clients to, agencies in a wide range of sectors. Relationships with participatory structures at community level stimulated coordinated responses from service providers. In contrast, an absence of these elements curtailed the ability of CHWs in the small NGO and government-initiated service to provide effective outreach services or to improve access to care.
Conclusion:
Significant investment in resources, training, and support can enable CHWs to address barriers to care by negotiating with poorly functioning government services and community participation structures.
Repair of left ventricular driveline tear in a SynCardia-total artificial heart patient
Authors: Sotirios Spiliopoulos, Magda Tenderich, Dilek Guersoy, Guenes Dogan, Reiner Koerfer, Gero Tenderich
Journal: J Cardiothorac Surg (2014)
MeSH terms: Heart Failure / surgery, Heart-Assist Devices / adverse effects, Case Reports, Heart Ventricles, Humans, Male, Middle Aged, Prosthesis Design, Prosthesis Failure, Reoperation

We report the case of a 64-year old Caucasian male patient with a tear of the left ventricular driveline just above the driveline-air tube junction. We describe the repair technique and the necessary set of tools.
Atrio-Esophageal Fistula: A Rare Entity Complicating a Common Procedure
Authors: I A Sanoja
Journal: Case Rep Crit Care (2023)
MeSH terms: Case Reports

A 66-year-old female with a history of radiofrequency ablation for atrial fibrillation presented with hematemesis and fever. A CT chest revealed an atrio-esophageal fistula (AEF) and a CT head showed bilateral septic emboli. Blood cultures were positive for Streptococcus sanguinis. She underwent primary repair of the atrial defect on cardiopulmonary bypass where a large atrial vegetation was retrieved, followed by a right thoracotomy with the closure of the esophageal defect the next day. She was discharged to a rehabilitation facility after 18 days of hospital stay with a 6 weeks antibiotics plan. The incidence of AEF following ablation procedures has been estimated at 0.01 to 0.04%, and the pathogenesis is linked to direct tissue and vagus nerve injury. The most common clinical findings are fever and neurologic deficits. CT chest is the best diagnostic modality. CT head might demonstrate embolic phenomena and TTE can show vegetation. Early surgical intervention, even in an unstable patient, is paramount for survival.
Radiation-Induced Alopecia after Endovascular Embolization under Fluoroscopy
Authors: Vipawee Ounsakul, Wimolsiri Iamsumang, Poonkiat Suchonwanit
Journal: Case Rep Dermatol Med (2016)
MeSH terms: Case Reports

Radiation-induced alopecia after fluoroscopically guided procedures is becoming more common due to an increasing use of endovascular procedures. It is characterized by geometric shapes of nonscarring alopecia related to the area of radiation. We report a case of a 46-year-old man presenting with asymptomatic, sharply demarcated rectangular, nonscarring alopecic patch on the occipital scalp following cerebral angiography with fistula embolization under fluoroscopy. His presentations were compatible with radiation-induced alopecia. Herein, we also report a novel scalp dermoscopic finding of blue-grey dots in a target pattern around yellow dots and follicles, which we detected in the lesion of radiation-induced alopecia.
Return to duty/play after exertional heat injury: do we have all the answers? A lesson from two case studies
Authors: Itay Ketko, Amit Druyan, Ran Yanovich, Yoram Epstein, Yuval Heled
Journal: Disaster Mil Med (2015)
Keywords: exercise, heat injury, heat tolerance test, thermoregulation
MeSH terms: Case Reports

Background:
The common practice in the Israel defense Forces is that exertional heat related injury patients undergo a heat tolerance test 6-8 weeks post event as part of the "return to duty" process. In the case of a positive heat tolerance test the individual is classified as heat intolerant, in some cases however, the thermoregulatory recovery may be longer (several months), and therefore a second heat tolerance test is scheduled 6-8 weeks later. The presented case reports emphasize the possibility of different recovery periods of the thermoregulatory center and the distinction between congenital and acquired physiological heat intolerance.
Case description:
Two young healthy males (A and B) were diagnosed with exertional heat related injury during a pre-recruitment sorting process. Both underwent a heat tolerance test, and were found heat intolerant. During the next months they repeated the test several times. Patient A was finally diagnosed as heat tolerant and patient B was diagnosed as heat intolerant.
Conclusion:
Susceptibility to heat is a significant determinant for active young people such as athletes and soldiers. Both cases emphasize the importance of the heat tolerance test (and repeated test when needed) as a criteria for an exertional heat related injury patient to return to duty/play and to perform intense physical activities. These cases also emphasize the effectiveness and sensitivity of the test in identifying a temporary and a permanent state of heat intolerance.
Primary mesenteric sertoli-leydig cell tumor: a case report and review of the literature
Authors: Amel Trabelsi, Soumaya Ben Abdelkarim, Mohamed Hadfi, Ridha Fatnaci, Wided Stita, Badreddine Sriha, Sadok Korbi
Journal: J Oncol (2008)
MeSH terms: Case Reports

The occurrence of primary sex cord-stromal tumors at extraovarian sites is exceedingly rare. We report a new case of Sertoli-Leydig cell tumor in the mesentery of a 78-year-old woman who presented with occlusive syndrome and reviewed the previously reported cases of extraovarian sex cord-stromal tumors in the English literature.