OpenMed/multicare-articles huggingface dataset:
Breast fistula repair after autologous fat graft: a case report
Authors: Francesco Maria Klinger, Fabio Caviggioli, Davide Forcellini, Valeriano Vinci, Luca Maione, Giorgio Pajardi, Marco Klinger
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

We report the case of a 55-year-old female patient who attended our clinic for the presence of a scar retraction in the upper pole of the left breast as a complication of breast augmentation. In the scar area, we observed an orifice that probing revealed to be a fistula. The patient was referred to surgical intervention under general anesthesia to obtain scar contracture release using autologous fat graft; one month after autologous fat injection, following healing of the fistula, the patient underwent a second surgical procedure to replace the left breast implant. Unexpectedly, two weeks after the surgical procedure, complete healing of the breast fistula within the scar area was observed; this observation was confirmed during the second surgical step for left breast implant repositioning, when we observed the absence of the fistula orifice in the breast implant cavity. Upon clinical examination at 1-year followup, tissue integrity was preserved. The patient's satisfaction was excellent. We have observed a possible additional effect of fat graft.
B-Cell Lymphoma Producing IgM Anti-B Antibody: A Case Report
Authors: Feiyu Jiang, Tiejun Song, Yingjian Wang, Zhiwei Liu
Journal: Front Med (Lausanne) (2022)
Keywords: abo blood group discrepancy, b-cell lymphoma, case report, genotyping, serology
MeSH terms: Case Reports

ABO blood group system is the most important blood group system in transfusion and transplantation medicine. Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphomas (NHLs) worldwide. There have been some studies that lymphoma could affect ABO blood group system and thus affect blood transfusion strategy. However, the mechanisms lymphoma affecting ABO blood group system have not been fully elucidated so far. Here, we report a case of a patient who was a 72-year-old Chinese man came to our hospital for medical advice because of cervical lymphadenophathy. The patient was subsequently diagnosed with diffuse large B-cell lymphoma by lymph-node biopsy. His ABO blood group was initially typed as B on November 7, 2020. He was transfusing B type leukocyte poor RBCs (LPR) before we found the patient's ABO blood group discrepancy on December 2, 2020 by forward and reverse typing methods, which the discrepancy was verified by genotyping. The patient began to transfuse O type washed RBCs (WRBC) since then. Compared to transfuse B type leukocyte poor RBCs (LPR), the efficiency of transfusing O type washed RBCs (WRBC) was better. Although hemoglobin level did not greatly improve, indirect bilirubin level evidently decreased. Furthermore, we found B-cell lymphoma affected blood transfusion strategy by producing IgM anti-B antibody in this case. Clinicians should need to be aware of the effect of B-cell lymphoma on blood transfusion strategy.
Laparoscopic Management of Isolated Splenic Hydatid Disease in a Rural Centre: A Case Report
Authors: Stephanie E Cornish
Journal: Cureus (2023)
Keywords: hydatid disease, laparoscopic, rural, spleen, splenic hydatidosis
MeSH terms: Case Reports

Hydatid disease affects a significant proportion of the world's population, particularly in endemic areas, with substantial associated morbidity and mortality. However, the incidence of splenic involvement is rare, and isolated splenic disease is even more so; it is infrequently encountered in western countries. As such, their management is often limited to metropolitan tertiary centres with no fixed consensus on the best surgical approach. The author presents a case of the successful management of isolated splenic hydatid disease using a laparoscopic approach in a rural facility, in what is believed to be the first presented Australian case of isolated splenic hydatidosis.
Hyperthyroidism With Atrial Fibrillation in Children: A Case Report and Review of the Literature
Authors: Deepa Subramonian, Yuwei Juliana Wu, Shazhan Amed, Shubhayan Sanatani
Journal: Front Endocrinol (Lausanne) (2021)
Keywords: arrhythmia, atrial fibrillation, cardioversion, heart, hyperthyroidism, thyroid hormones
MeSH terms: Antithyroid Agents / therapeutic use, Atrial Fibrillation / etiology, Hyperthyroidism / complications, Methimazole / therapeutic use, Case Reports, Review, Adolescent, Atrial Fibrillation / physiopathology, Electrocardiography, Female, Humans, Hyperthyroidism / drug therapy, Hyperthyroidism / physiopathology, Thyroid Function Tests, Treatment Outcome, Antithyroid Agents, Methimazole

Atrial fibrillation is exceedingly rare in children with structurally and functionally normal hearts. We present a novel case of a 15-year-old female with known hyperthyroidism who subsequently developed atrial fibrillation. She had been suffering from fatigue, heat intolerance and myalgias for 6 months. Her initial TSH was 0.01mU/L, and free T4 was 75.4 pmol/L, with a free T3 of >30.8 pmol/L. An electrocardiogram showed atrial fibrillation with a ventricular rate of 141 beats per minute. An echocardiogram demonstrated an enlarged left atrium and ventricle, with mild mitral regurgitation. She was treated with methimazole and underwent synchronized cardioversion. She subsequently returned to a euthyroid state and remained in normal sinus rhythm. In this case, we discuss the physiologic and arrhythmogenic properties of thyroid hormone, with a summary of the existing literature on atrial fibrillation in hyperthyroidism in children. Current guidelines for treatment of atrial fibrillation are also outlined.
A Case of Recurrent Erysipelas Caused by Streptococcus mitis Group
Authors: David Nygren, Bo Nilson, Magnus Rasmussen
Journal: Case Rep Infect Dis (2018)
MeSH terms: Case Reports

The aetiology of erysipelas remains poorly defined though beta-haemolytic streptococci are considered as the main causative pathogens. We describe a case of a 70-year-old woman with recurrent erysipelas in her left arm due to infection with streptococci of the mitis group. Her past medical history includes lymphoedema of the left arm secondary to lymph node dissection due to breast cancer surgery. On seven different occasions during a decade, she has presented a clinical picture of erysipelas and in three of them with Streptococcus mitis group bacteraemia. The results indicate that two cases were caused by Streptococcus mitis and one case was caused by Streptococcus oralis. This is, to our knowledge, the first reported cases of S. mitis and of S. oralis as the causative agents of erysipelas.
Simultaneous Bilateral Proximal Humerus Fractures Treated with Single-Stage Bilateral Reverse Shoulder Arthroplasty
Authors: Taiki Tokuhiro, Atsushi Urita, Yusuke Kameda, Makoto Motomiya, Naoya Watanabe, Norimasa Iwasaki
Journal: Case Rep Orthop (2022)
MeSH terms: Case Reports

Introduction:
Simultaneous bilateral fractures of the proximal humerus are infrequent, and simultaneous bilateral three- or four-part fractures are even rarer. Reverse shoulder arthroplasty (RSA) is being used increasingly for the treatment of three- and four-part fractures of the proximal humerus. However, treatment of simultaneous bilateral fractures of the proximal humerus is difficult because of concern about postoperative immobilization and rehabilitation. Case Presentation. A 75-year-old woman presented with bilateral shoulder pain subsequent to a fall on the street. Physical examination and radiographs showed simultaneous bilateral fractures of the proximal humerus. The right side fracture was classified as a four-part fracture and the left side fracture as a three-part fracture, according to Neer's classification. The right shoulder had a risk of avascular necrosis of the humeral head. For the left shoulder, the fracture type had caused ischemia of the humeral head. Single-stage bilateral RSA was performed 9 days after the injury. An abduction pillow was applied for 5 weeks postoperatively. Passive motion exercises were permitted starting at 4 weeks postoperatively, and active range of motion exercises were permitted at 6 weeks postoperatively. At the patient's most recent follow-up 30 months after surgery, the patient reported no restriction of the activities of daily living. Radiographs revealed no lucent line on the humerus and glenoid components, although bone resorption and superior retraction of the tuberosities on both sides were observed.
Conclusions:
Single-stage bilateral RSA improved shoulder function, but healing of the greater tuberosity can affect the improvement in external rotation after the operation. Although a long-term follow-up is needed, single-stage bilateral RSA appears to be a viable treatment option.
Combined central retinal artery and vein occlusion following trabeculectomy
Authors: Albert John Bromeo, Sweet Jorlene Lerit, Patricia Grulla-Quilendrino, George Michael Sosuan, Edgar Leuenberger
Journal: GMS Ophthalmol Cases (2022)
Keywords: glaucoma, retinal artery occlusion, retinal vein occlusion, trabeculectomy
MeSH terms: Case Reports

Retinal vascular events may occur as rare complications of glaucoma procedures due to various factors, including exacerbation of ischemia in patients with pre-existing vascular comorbidities, toxic effect of mitomycin-C, and decompression retinopathy. We present the case of a 47-year-old hypertensive male who underwent trabeculectomy for advanced glaucoma in his right eye. At 3 weeks postoperatively, he presented with a drop in visual acuity to light perception with a spike in intraocular pressure. On examination, there was increased bleb vascularity as well as rubeosis. Fundoscopy revealed findings consistent with both central retinal artery occlusion and central retinal vein occlusion. Combined central retinal artery and vein occlusion is a rare retinal vascular condition. Neovascular glaucoma can occur as a sequelae of the ischemic process in the retina. Despite treatment, there is a poor visual prognosis, with the affected eye usually becoming blind from optic atrophy and neovascularization.
The Role of Patiromer in Delaying the Onset of Renal Replacement Therapy in Patients with Advanced Renal Failure
Authors: Nand K Wadhwa, Jason A Kline, Sreedhar R Adapa
Journal: Case Rep Nephrol (2021)
MeSH terms: Case Reports

Patients with chronic kidney disease (CKD) are at an increased risk of developing hyperkalemia, which can be potentially life threatening. Hyperkalemia is frequently encountered with renin-angiotensin-aldosterone system inhibitor (RAASi) therapy use in patients with CKD and often results in the underdosing or discontinuation of these drugs. RAASi therapy has been proven to delay the progression of CKD, ameliorate proteinuria, and reduce the overall risk of cardiovascular morbidity and mortality. Patiromer is a sodium-free, potassium-binding polymer used for the treatment of hyperkalemia. We present a case series of four patients with Stage 4 or 5 CKD in whom the initiation of dialysis was delayed with the use of patiromer. For one patient, dialysis was delayed by 18 months, whereas the remaining three patients, in whom hyperkalemia was one of the main complications, remain dialysis independent to date.
Ischemic Stroke Secondary to Myocarditis in the Setting of COVID-19
Authors: Tarakarama Musunuri, Patrick M Muehlberger
Journal: Cureus (2023)
Keywords: cardiomyopathy, covid 19, ischemic stroke, myocardidits, stroke, thrombo embolic disease
MeSH terms: Case Reports

Coronavirus disease (COVID-19) is primarily a respiratory disease that has also been shown to be associated with neurological complications such as ischemic stroke, Guillain-Barré syndrome, and encephalitis. Ischemic stroke in patients with COVID-19 has mostly been observed in the elderly, those with significant comorbidities, and the critically ill. In this report, we discuss a case of ischemic stroke in an otherwise healthy young male patient who only had a mild case of COVID-19. It is likely that the patient suffered from an ischemic stroke secondary to cardiomyopathy that resulted from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The ischemic stroke was most likely a result of thromboembolism caused by stasis of blood from acute dilated cardiomyopathy and the hypercoagulable state of COVID-19 patients. It is important to maintain a high degree of clinical suspicion for thromboembolic events in COVID-19 patients.
Percutaneous Coronary Intervention in a Patient with Right-Sided Heart: Invert the Views?
Authors: Miguel López Hidalgo, Risshi D Rampersad
Journal: Case Rep Cardiol (2018)
MeSH terms: Case Reports

Situs inversus totalis considered a malposition syndrome is a very rare condition, occurring in 1 : 8000 births, usually without associated structural congenital heart disease. The diagnosis is often incidental as in this case, which presented with an acute coronary syndrome as a manifestationof multivessel coronary artery disease. Here, we present the challenges encountered during the diagnosis and management of this entity via percutaneous intervention.
Connecting hospitalized patients with their families: case series and commentary
Authors: Kourosh Parsapour, Alexander A Kon, Madan Dharmar, Amy K McCarthy, Hsuan-Hui Yang, Anthony C Smith, Janice Carpenter, Candace K Sadorra, Aron D Farbstein, Nayla M Hojman, Gary L Wold, James P Marcin
Journal: Int J Telemed Appl (2011)

The overall aim of this project was to ascertain the utilization of a custom-designed telemedicine service for patients to maintain close contact (via videoconference) with family and friends during hospitalization. We conducted a retrospective chart review of hospitalized patients (primarily children) with extended hospital length of stays. Telecommunication equipment was used to provide videoconference links from the patient's bedside to friends and family in the community. Thirty-six cases were managed during a five-year period (2006 to 2010). The most common reasons for using Family-Link were related to the logistical challenges of traveling to and from the hospital-principally due to distance, time, family commitments, and/or personal cost. We conclude that videoconferencing provides a solution to some barriers that may limit family presence and participation in care for hospitalized patients, and as a patient-centered innovation is likely to enhance patient and family satisfaction.
Novel MRPS9-ALK Fusion Mutation in a Lung Adenocarcinoma Patient: A Case Report
Authors: Huamiao Zhou, Binyue Xu, Jili Xu, Guomeng Zhu, Yong Guo
Journal: Front Oncol (2021)
Keywords: alk-tki, mrps9-alk, ngs, nsclc, crizotinib
MeSH terms: Case Reports

Anaplastic lymphoma kinase (ALK) rearrangements account for approximately 5-6% of non-small-cell lung cancer (NSCLC) patients. In this study, a case of lung adenocarcinoma harboring a novel MRPS9-ALK fusion is reported. The patient responded well to the first and second generation of ALK-tyrosine kinase inhibitors (ALK-TKIs) (crizotinib then alectinib), as her imaging findings and clinical symptoms significantly improved. At last follow-up, over 21 months of overall survival (OS) has been achieved since ALK-TKI treatment. The progression-free survival (PFS) is already ten months since alectinib. The adverse effects were manageable. The case presented here provides first clinical evidence of the efficacy of ALK-TKIs in NSCLC patients with MRPS9-ALK fusion.
Safe Transition to Pembrolizumab following Ipilimumab-Induced Guillain-Barré Syndrome: A Case Report and Review of the Literature
Authors: Nicholas Gravbrot, Katalin Scherer, Srinath Sundararajan
Journal: Case Rep Oncol Med (2019)
MeSH terms: Case Reports

Background:
Immune checkpoint inhibitors are novel therapies with indications for treating several solid cancers. They are associated with immune-related adverse events, which are generally well tolerated. Though rare, severe side effects may be life-threatening. One such adverse event is Guillain-Barré syndrome, which requires cessation of the immunotherapy and intravenous immunoglobulin and/or high-dose steroids to treat. No recommendations have been published regarding restarting cancer treatment after development of immunotherapy-induced Guillain-Barré syndrome.
Case presentation:
A 71-year-old gentleman with recurrent, stage IIIB melanoma was started on ipilimumab (cytotoxic T lymphocyte antigen-4 inhibitor) for adjuvant treatment following radical neck dissection and radiation therapy. After completing his third cycle of ipilimumab, he developed rapidly progressive ascending paralysis. He was diagnosed with ipilimumab-induced atypical Guillain-Barré syndrome and was treated with intravenous immunoglobulin and corticosteroids. Ipilimumab was discontinued, and the patient was monitored via surveillance imaging, as there was no evidence of active disease at that time. Several months later, he was found to have recurrent disease involving the lung, requiring right lower lobectomy. Restaging revealed thoracic lymph node involvement, and he was then started on pembrolizumab (programmed cell death protein-1 inhibitor). He experienced a complete tumoral response to pembrolizumab, and he tolerated treatment well without recurrent weakness.
Conclusions:
Guillain-Barré syndrome is a rare but severe complication associated with immunotherapy. Our findings suggest that in patients with a history of ipilimumab-induced Guillain-Barré syndrome, pembrolizumab may possibly be a safe and effective alternative for cancer therapy.
Repair of Penetrating Pericardial and Diaphragmatic Injury with Cormatrix® Patch in a Case of Suicide Attempt
Authors: Federica Jiritano, Carlo Garrasi, Lucia Cristodoro, Egidio Bevacqua, Pasquale Mastroroberto
Journal: Braz J Cardiovasc Surg (2017)
MeSH terms: Diaphragm / surgery, Pericardium / surgery, Suicide, Attempted, Thoracic Injuries / surgery, Wounds, Penetrating / surgery, Case Reports, Diaphragm / injuries, Humans, Male, Middle Aged, Pericardium / injuries, Tomography, X-Ray Computed

The authors report the case of a suicide attempt. A 59-year-old man with self-inflicted penetrating chest trauma underwent emergency cardiothoracic surgery. Pre-operative computed tomography scan showed critical proximity between the blade and the right ventricle. Intraoperative findings showed a pericardial laceration and a huge diaphragmatic lesion with heart and abdominal organs integrity. The diaphragm muscle was repaired with a CorMatrix® patch, an acceptable alternative to the traditional synthetic mesh avoiding infection and repeated herniation.
Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review
Authors: Tarun Girotra, Abhimanyu Mahajan, Christos Sidiropoulos
Journal: Case Rep Neurol Med (2017)
MeSH terms: Case Reports

Hemochromatosis is an autosomal recessive disorder which leads to abnormal iron deposition in the parenchyma of multiple organs causing tissue damage. Accumulation of iron in the brain has been postulated to be associated with several neurodegenerative diseases including Parkinson's disease. The excess iron promotes Parkin and α-synuclein aggregation in the neurons. Excess iron has also been noted in substantia nigra on MRI especially using susceptibility weighted imaging in patients with Parkinson's disease. We present a case of a young male with alleles for both C282Y and H63D who presented with signs of Parkinsonism and demonstrated significant improvement with levodopa treatment.
Clinical results of tricuspid valve replacement - a 21-case report
Authors: Yu Zhuang, Jie Zhou, Mingdi Xiao, Zhongxiang Yuan, Chengbao Lu, Min Yu, Lei Lin
Journal: J Biomed Res (2010)
Keywords: cardiac function, heart valve diseases, tricuspid valve replacement

Objective:
To summarize the clinical experiences of 21 patients treated with tricuspid valve replacement (TVR) and investigate the surgical indications and methods.
Methods:
Data from 21 patients who underwent TVR from December 2002 to March 2009 were retrospectively collected and analyzed. The mean age was 48.86±15.37 years (range: 20-72 years). The underlying disease of the patients was classified as rheumatic (n = 10), congenital (n = 8), endocarditis (n = 2) or chest trauma (n = 1). Previous cardiac surgery had been performed in 12 patients (57.14%).
Results:
In-hospital death occurred in two patients (9.52%). Postoperative morbidities included cardiac failure (n = 2), bleeding related re-operation (n = 1), and plural effusion (n = 2).
Conclusion:
The early outcomes of TVR were acceptable. At the present time TVR can be performed through optimal perioperative management.
Exposure to particulate matter (PM2.5) and volatile organic compounds (VOCs), and self-reported health symptoms among fish smokers: A case study in the Western Region of Ghana
Authors: Gifty Mensah Obeng, Simon Appah Aram, Daniel Agyei, Benjamin M Saalidong
Journal: PLoS One (2023)
MeSH terms: Air Pollutants / adverse effects, Air Pollutants / analysis, Air Pollution, Indoor / adverse effects, Air Pollution, Indoor / analysis, Volatile Organic Compounds / analysis, Cross-Sectional Studies, Environmental Monitoring, Ghana / epidemiology, Humans, Particulate Matter / adverse effects, Particulate Matter / analysis, Self Report, Smokers, Particulate Matter, Volatile Organic Compounds, Air Pollutants

The study aimed to assess the concentrations of particulate matter (PM2.5) and volatile organic compounds (VOCs) produced from the burning of biomass fuel from the smoking of fish. It also sought to determine the proportion of fish smokers reporting health symptoms associated with exposure to these pollutants. A cross-sectional study was conducted among fish smokers at Abuesi in the Western Region of Ghana. Systematic sampling was employed to choose 60 smokehouses for PM2.5 and VOC monitoring. A total of 434 fish smokers were also randomly sampled for the study. Measurements were taken at indoor, outdoor and control locations. The highest concentration of PM2.5 was recorded in the indoor environment. The mean concentration of PM2.5 between the indoor and control environment was significantly different unlike between the outdoor and control environments. The concentration of VOCs systematically varied across indoor, outdoor and control locations. The most reported disease symptoms were eye infection, cough, and headaches. There was a strong positive association between the number of years spent smoking fish and the frequency of eye problems reported by fish smokers. The study demonstrated that fish smokers inside the smokehouse or smoking rooms are exposed to higher PM2.5 and VOC levels which are detrimental to their health. There is therefore the need for further studies to explore other energy sources which may have a lesser negative effect on human health.
177Lu-Dotatate therapy for the treatment of metastatic neuroendocrine tumours in a patient on haemodialysis-dosimetric considerations
Authors: Eleni Kalogianni, Danielle Louise Ruiz, Benjamin James Corcoran, Lindsey Ann Devlin, Gillian Claire Vivian, Nicola Jane Mulholland
Journal: BJR Case Rep (2015)
MeSH terms: Case Reports

We report on a case of a 68-year-old female, currently a dialysis-dependant patient with disseminated metastatic neuroendocrine tumour, treated with 177Lu-Dotatate. As 177Lu-Dotatate is cleared predominantly by the kidneys, there are concerns regarding the treatment plan strategy to avoid increased radiation exposure compared with patients with normal renal function. For this purpose, personalized dosimetry was used to calculate the safe administered activity using whole-body scans. Employing this strategy allowed us to adjust the administered activity for the third fraction. The whole-body doses calculated were not significantly different from those received by patients with normal renal function. The radiological follow-up showed a stable disease, suggesting effective treatment. We found negligible radiation protection problems involved with this procedure.