OpenMed/multicare-articles huggingface dataset:
Repair of Tendon Disruption Using a Novel Synthetic Fiber Implant in Dogs and Cats: The Surgical Procedure and Three Case Reports
Authors: Philippe Buttin, Bastien Goin, Thibaut Cachon, Eric Viguier
Journal: Vet Med Int (2020)

Surgical management of tendon rupture is challenging. One concern is to provide adequate tensile strength to prevent distraction during weight-bearing and gap formation following repair, associated with an increased risk of repair failure. Additional challenges may arise from the nature or the chronicity of the lesion. In the event of avulsion, when the tendon is torn off at the bone insertion, its reinsertion on the bone is generally difficult and may even be impossible in the presence of an avulsion fracture, especially when the bone fragment is too small or fragmented. Repair management is also complicated in chronic cases, as degeneration of the tendon may lead to excessive scar tissue formation, tendon retraction, and muscle atrophy, resulting in a large gap and inadequate tissue for reconstruction. The authors describe the surgical procedure for implanting a novel implant, illustrated by three characteristic clinical cases: (1) an acute Achilles tendon avulsion; (2) a chronic patellar tendon rupture; and (3) a chronic avulsion fracture of the triceps tendon. In these three cases, complete recovery of the function was observed at the last clinical evaluation (6 or 8 months), and no complication was noted. A splinted dressing (6 to 8 weeks) was used successfully in two cases. A resin cast (8 weeks) was preferred in case 1, a very active dog. In conclusion, this novel implant represents a simple procedure for the effective repair of chronic tendon rupture, as well as an effective tendon reinsertion on the bone and adequate support for bone tendon healing in the treatment of tendon avulsion, even in cases of fragmented bone fracture. The thinness of the implant facilitates its insertion into the native tendon, while the bone-screw-implant interface provides immediate and lasting mechanical support. This may facilitate the healing process and potentially shorten the period of immobilization.
Tc-MDP bone scintigraphy in a case with sporodical tumoral calcinosis
Authors: Tulay Kacar Guveli, Mehmet Mulazimoglu, Muge Oner Tamam, Cüneyt Tamam, Tarik Tatoglu, Tevfik Ozpacaci
Journal: Indian J Nucl Med (2010)
Keywords: sporadical tumoral calcinosis, tc-mdp bone scintigraphy, juxta-articular regions
MeSH terms: Case Reports

Tumoral calcinosis is an uncommon and benign condition characterized by the presence of large calcific soft tissue deposits occurring predominantly in a periarticular location. It generally occurs as a complication of renal dialysis or trauma, and is rarely seen in familial and sporadic cases. Bone scintigraphy is a sensitive method for diagnosing tumoral calcinosis. A 28-year-old female patient with a history of operation due to tumoral calcinosis located bilateral hips, referred to our department. She had a tender palpable mass in the right knee and a fistulized incisional scar overlying the bilateral hip joints. A sporadic case of tumoral calcinosis with relapses was presented.
Benign metastasizing leiomyoma: a rare type of lung metastases-two case reports and review of the literature
Authors: Rokana Taftaf, Sandra Starnes, Jiang Wang, Ralph Shipley, Tariq Namad, Rana Khaled, Nagla Abdel Karim
Journal: Case Rep Oncol Med (2014)

Benign metastasizing leiomyoma (BML) is a rare disease that usually occurs in women of reproductive age. They typically have history of uterine leiomyoma treated with hysterectomy. BML can metastasize to distant organs, with the lung being the most common organ. We report two patients who presented with benign metastasizing leiomyoma to the lung. Our first case was a fifty-two-year-old female who presented with multiple lung masses, with a past medical history of uterine leiomyoma who underwent hysterectomy 17 years ago. A CT-guided biopsy showed benign appearing spindle cells and pathology confirmed her diagnosis with additional positive estrogen/progesterone receptor stains. Our second case was a fifty-six-year-old female who presented with multiple cavitary pulmonary nodules. She subsequently underwent a video-assisted thoracoscopic surgery (VATS) with wedge resection of one of the nodules. Pathology confirmed the diagnosis based on morphology and immunohistochemical staining strongly positive for estrogen/progesterone receptors. Benign metastasizing leiomyoma is a rare condition which may affect women of reproductive age. This should be considered in the differential in patients who present with multiple pulmonary nodules, especially with a history of uterine leiomyoma. Additional stains, such as estrogen/progesterone receptors, may need to be done to confirm the diagnosis.
External tissue expansion to salvage failed scalp and forehead reconstruction: a case report
Authors: Peter Y W Chan, Elina Patel, Ethan Paulin, Ajul Shah
Journal: Case Reports Plast Surg Hand Surg (2022)
Keywords: tissue expansion, cranial reconstruction, salvage, salvage reconstruction, scalp reconstruction
MeSH terms: Case Reports

The reconstruction of forehead and scalp defects is a difficult task. Common reconstructive methods are associated with multiple complications and may fail, requiring a difficult second surgery. We present the use of external tissue expansion as a method to achieve effective closure of a failed scalp and forehead reconstruction.
Epipericardial fat necrosis as a differential diagnosis of acute chest pain: a case report and algorithm proposal for diagnostic approach
Authors: Tarso Augusto Duenhas Accorsi, Milena Ribeiro Paixão, Erick de Moraes Santos Piorino, Karine De Amicis, Karen Francine Köhler, José Leão de Souza Jr
Journal: Einstein (Sao Paulo) (2023)
MeSH terms: Fat Necrosis / diagnosis, Fat Necrosis / diagnostic imaging, Case Reports, Adult, Chest Pain / diagnostic imaging, Chest Pain / etiology, Diagnosis, Differential, Emergency Service, Hospital, Humans, Male, Ultrasonography

Chest pain is a frequent, potentially life-threatening condition in the emergency department and requires immediate investigation and treatment. This case report highlights a rare differential diagnosis of pleuritic chest pain: epipericardial fat necrosis. A 29-year-old man presented with normal clinical evaluation, electrocardiography, point-of-care ultrasound, and unremarkable laboratory tests. The initial hypothesis was acute pleuritis. Chest radiography revealed peri-cardiac nonspecific findings, and computed tomography revealed epicardial fat necrosis. Despite the rarity of this condition, accurate diagnosis allows for better practices. An algorithm for a diagnostic approach is proposed.
A Rare Case of Achondroplasia With Bilateral Developmental Cataract
Authors: Rasika Bagewadi, Pravin Tidake, Sandhya Jeria, Mayur B Wanjari
Journal: Cureus (2023)
Keywords: achondroplasia, cataract, developmental cataract, genetic syndromes, posterior polar cataract
MeSH terms: Case Reports

Enchondral ossification disorders of autosomal dominant congenital origin include achondroplasia, among others. Low stature, craniofacial deformity, and spinal abnormality are its clinical hallmarks. Some of the associated ocular characteristics are telecanthus, exotropia, angle abnormalities, and cone-rod dystrophy. A 25-year-old female presented to the Ophthalmology outpatient department (OPD) with the classical clinical signs of achondroplasia and developmental cataracts in both eyes. She also had associated esotropia in the left eye. Achondroplasia patients should be screened for developmental cataracts to enable timely intervention and management.
The Rare Cases of Parotid Gland Arteriovenous Malformations
Authors: Manish Gupta, Vijay Shrawan Nijhawan, Cynthia Kaur, Sukhpreet Kaur, Akanksha Gupta
Journal: Case Rep Otolaryngol (2021)
MeSH terms: Case Reports

Arteriovenous malformation (AVM) results from errors in vascular development during embryogenesis; absent capillary beds lead to shunting directly from the arterial to venous circulation. Although it is common in the head and neck region, AVMs located in the parotid gland are quite rare. Here, we report two cases of arteriovenous malformation of the parotid gland that presented to our out-patient setup with swelling in the parotid region and were diagnosed as arteriovenous malformation on histopathological study after surgical resection.
Newly Diagnosed Colonic Adenocarcinoma: The Presenting Sign in a Young Woman with Undiagnosed Crohn's Disease in the Absence of Primary Sclerosing Cholangitis and a Normal Microsatellite Instability Profile
Authors: Brett Matthew Lowenthal, Ann M Ponsford Tipps
Journal: Case Rep Pathol (2017)
MeSH terms: Case Reports

Ulcerative colitis has long been linked with an increased risk for colonic adenocarcinoma, whereas Crohn's disease (CD) has recently been reported to pose a similar increased risk. We report a 33-year-old healthy female with no family history who presented with abdominal pain and a colon mass. Histopathology revealed a moderately differentiated adenocarcinoma extending through the muscularis propria with metastatic lymph nodes and intact mismatch repair proteins by immunohistochemical expression and gene sequencing. The nonneoplastic grossly uninvolved background mucosa showed marked crypt distortion, crypt abscesses, CD-like lymphoid hyperplasia, transmural inflammation, and reactive epithelial atypia. Additional patient questioning revealed frequent loose stools since she was a teenager leading to diagnosis of a previously undiagnosed CD without primary sclerosing cholangitis (PSC). The adenocarcinoma is suspected to be related to the underlying CD. Newly diagnosed adenocarcinoma in a young female as the presenting sign for CD in the absence of PSC is extremely rare.
Blood pressure shifts resulting from a concealed arteriovenous fistula associated with an iliac aneurysm: a case report
Authors: Shintaro Doi, Yoshiaki Motoyama, Hiromi Ito
Journal: JA Clin Rep (2016)
Keywords: abdominal aortic aneurysm, arteriovenous fistula, hemodynamics, iliac artery

Background:
A solitary iliac aneurysm (SIA) is more uncommon than an abdominal aortic aneurysm. The aneurysm is located in the deep pelvis and is diagnosed when it reaches a large size with symptoms of compression around adjacent structures and organs or when it ruptures. A definite diagnosis of an arteriovenous fistula (AVF) associated with a SIA is difficult preoperatively because there might not be enough symptoms and time for diagnosis. Here, we present a patient with asymptomatic rupture of SIA into the common iliac vein with characteristic blood pressure shifts.
Case presentation:
A 41-year-old man with a huge SIA underwent aortobifemoral graft replacement. Preoperatively, his blood pressure showed characteristic shifts for one or two heartbeats out of five beats, indicating that an AVF was present and that the shunt was about to having a high flow. During surgery, an AVF associated with the SIA was found to be concealed owing to compression from the huge iliac artery aneurysm, and the shunt showed a high flow, resulting in shock during the surgery. No complications were noted after aortobifemoral graft replacement. Postoperatively, we noted an enhanced paravertebral vein on computed tomography (CT), which indicated the presence of an AVF.
Conclusions:
Definite diagnosis of an AVF offers advantages in surgical and anesthetic management. We emphasize that a large SIA can push the iliac vein and occlude an AVF laceration, concealing the enhancement of the veins in the arterial phase on CT. Blood pressure shifts might predict the existence of a concealed AVF that has a large shunt. Even if the vena cava and the iliac veins are not enhanced on CT, anesthesiologists should carefully determine whether their distal branches are enhanced.
A Unique Case of Deficiency of Adenosine Deaminase 2 Single in a Young Adult Patient
Authors: Atheer Alharthi, Ghaith R Alhashmi Alamer, Saif S Alqurashi, Emad E Alsaeedi, Hasheema Alsulami
Journal: Cureus (2023)
Keywords: adult onset, case report, dada2, deficiency of adenosine deaminase 2, saudi arabia
MeSH terms: Case Reports

Deficiency of adenosine deaminase 2 (DADA2) is a rare monogenic disease caused by mutations in the adenosine deaminase 2 gene (ADA2). It is characterized by a wide range of manifestations, including systemic inflammation and vasculopathy, early onset stroke (ischemic or hemorrhagic), immunodeficiency, and bone marrow failure. The diagnosis of DADA2 is confirmed by pathogenic mutations in ADA2 or low ADA2 enzymatic activity in the patient. In this study, we present a case of a 24-year-old Saudi male who was admitted with symptomatic anemia, lightheadedness, exertional symptoms, and a history of fever (38.1 C) for one week. Laboratory tests revealed normocytic normochromic anemia, leucopenia, lymphopenia, and neutropenia-autoimmune profile: low C3 and positive anti-ds DNA. The genetic testing revealed two Pathogenic variants, which were identified in ADA2. The diagnosis of DADA2 was made, and the patient received subcutaneous adalimumab 40 mg every two weeks. At the follow-up after one month, he showed improvement in fever, rash, and C-reactive protein (CRP) from (6 to 0.65). In conclusion, we present one of the first cases in Saudi Arabia of an adult patient diagnosed with DADA2 with a unique gene mutation. Adult-onset patients with DADA2 usually have a vague presentation and a relatively narrower phenotype range of symptoms which produce additional challenges for the physician to add DADA2 to the list of differentials. We suggest further studies investigate the genotype-phenotype association, possible clinical presentation, and the development of curative treatments for those cases.
Prenatal Three-Dimensional Ultrasound Detection of Adducted Thumbs in X-Linked Hydrocephaly: Two Case Reports with Molecular Genetic Studies
Authors: Edgardo Corral, Andres Barrios, Monica Isnard, Pascale Saugier-Veber, Sophie M Fortier, Sarah Durrin, Waldo Sepulveda
Journal: Case Rep Obstet Gynecol (2015)

X-linked hydrocephaly is a rare sex-linked genetic recessive condition occurring in 1/30,000 deliveries. Adduction of thumbs and mental retardation are additional associated clinical findings. We describe two cases of X-linked hydrocephaly with associated adducted thumbs that were diagnosed prenatally with the combined use of three-dimensional (3D) ultrasound and fetal blood sampling for cytogenetic and molecular analyses. This report suggests that 3D ultrasound can facilitate the identification of adducted thumbs in fetuses affected by X-linked hydrocephaly and supports evaluation of the fetal hands as an integral part of the ultrasound anatomical assessment in male fetuses with hydrocephaly secondary to aqueductal stenosis.
Track density imaging of hypertrophic olivary degeneration from multiple sclerosis plaque
Authors: Michael J Hoch, Sohae Chung, Girish M Fatterpekar, Ilya Kister, Timothy M Shepherd
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

A 32-year-old female with relapsing-remitting multiple sclerosis (MS) presented with severe new onset ataxia and diplopia. MRI showed a new inflammatory MS lesion that involved the right dorsal pons and extended into the adjacent superior cerebellar peduncle. The patient improved with aggressive immunotherapy; however, repeat MRI 3 months later revealed a new non-enhancing lesion in the left inferior medullary olive. The differential diagnosis for this new lesion included an MS lesion vs hypertrophic olivary degeneration, with infarct or neoplasm as the less likely considerations. We used track density imaging, which provides unprecedented anatomic details based on probabilistic tractography streamlines, to demonstrate apparent changes in the integrity of the dentato-rubro-olivary pathway (Guillain-Mollaret triangle) that were consistent with the diagnosis of hypertrophic olivary degeneration from the antecedent MS lesion involving the right superior cerebellar peduncle. Further medical therapy was avoided, and follow-up MRI 1 year later showed interval involution of the left olivary lesion. This case demonstrates the potential clinical utility of using track density imaging to detect lesion-induced alterations in brainstem connectivity and characterize neurodegeneration in patients.
Rickettsia conorii infection with fatal complication
Authors: Sanjoli Chugh, Priyanka Kumari, Shriya Goel, Manisha Biswal, Inderpaul Singh Sehgal, Aravind Sekar
Journal: Autops Case Rep (2022)
Keywords: autopsy, fatal outcome, fever, rickettsia infections, vasculitis
MeSH terms: Case Reports

Rickettsial diseases (RD) are a group of endotheliotropic infectious diseases caused by different species of genera Rickettsia. RD are not an uncommon disease and may be misdiagnosed during the evaluation of acute febrile illness due to a lack of reliable serological marker and diagnostic culture methods. Clinical manifestation of RD varies from febrile illness with rashes and myalgia to fatal complications such as shock and respiratory failure. We describe a case of a young male who presented initially with acute febrile illness, followed by shock and respiratory failure, and unfortunately succumbed to death. A post-mortem examination showed histological features of endotheliotropic infection, such as interstitial / perivascular edema in various organs and noncardiogenic pulmonary edema (suggesting increased vascular permeability) and evidence of vasculitis in the lung, liver, and intestines. Molecular studies performed from lung, liver, and kidney tissue confirm the diagnosis of spotted fever group rickettsial disease due to Rickettsia conorii.
Full Mouth Reconstruction of a Skeletal Class II Division 1 Patient with Adenoid Cystic Carcinoma Using an Interim Immediate Obturator and a Definitive Obturator
Authors: Mehran Bahrami, Seyed Mehran Falahchai
Journal: Case Rep Dent (2017)
MeSH terms: Case Reports

A 61-year-old female patient with adenoid cystic carcinoma (ACC) of the right maxilla and Angle class II division 1 malocclusion had received a subtotal maxillectomy in right side and used a conventional clasp-retained obturator. After implants placement, a maxillary interim immediate obturator (IIO) and then a definitive obturator using six endosseous implants were fabricated. During one-year follow-up, the patient was completely satisfied. Ideally, after implants placement in edentulous patients suffering from hemimaxillectomy, an implant-supported obturator (ISO) is designed in order to prevent nasal reflux and to improve speech and swallowing. However, in the following case, because of skeletal class II division 1 malocclusion and implants insertion in the premaxilla, using an ISO was impossible because it would cause excessive upper lip protrusion and lack of anterior teeth contact. Therefore, a five-unit implant-supported fixed partial denture (FPD) was fabricated in the maxillary anterior segment so that anterior teeth contacts were possible and the patient's normal lip support was achieved. A bar and three ball attachments were used in the maxillary posterior segment. A closed-hollow-bulb ISO was preferred. Conventional ISO in these patients results in several problems. Using a maxillary anterior FPD along with ISO caused satisfactory results in the current patient.
Case Report: Unprovoked venous thromboembolism in a young adult male
Authors: Jeyhan Dhabhar, Varshil Mehta, Nimit Desai, Sameer Dawoodi, Sojib Bin Zaman
Journal: F1000Res (2019)
Keywords: idiopathic, pulmonary embolism, thromboembolism
MeSH terms: Pulmonary Embolism, Venous Thromboembolism / diagnosis, Case Reports, Adult, Humans, Male, Stroke Volume, Uric Acid, Ventricular Function, Left, Young Adult, Uric Acid

A 24-year-old male was presented to us with sudden onset of chest pain and dyspnea for the past one hour. There was no history of calf pain, trauma, surgery, prolonged immobilization, long-haul air travel, bleeding diathesis or any other co-morbidity. The patient denied any addiction history. The heart rate was 114 beats/min, and blood pressure was 106/90 mmHg. Electrocardiogram showed tachycardia with S 1Q 3T 3 pattern. The left arterio-venous Doppler study was suggestive of a thrombus in popliteal vein and sapheno-popliteal junction. The CT-Pulmonary Angiogram scan was suggestive of a massive pulmonary thromboembolism. The patient was thrombolysed with Intravenous Alteplase immediately and was put on tab Rivaroxaban for maintenance. He was later discharged after being stable. Unprovoked venous thromboembolism (VTE) is very rare and has the potential to lead to pulmonary embolism which could be disastrous, especially in young adults. We present such a case where unprovoked VTE was diagnosed and treated. This case suggests that high clinical suspicion is the key for the diagnosis of acute pulmonary embolism, especially in the absence of history suggestive of deep vein thrombosis.
Traumatic right diaphragmatic rupture with hepatothorax in Ghana: two rare cases
Authors: Isaac Okyere, Perditer Okyere, Paul Sedem Komla Glover
Journal: Pan Afr Med J (2019)
Keywords: traumatic right diaphragmatic injury, blunt and penetrating chest injury, hepatothorax, thoracotomy
MeSH terms: Diaphragm / injuries, Liver / pathology, Wounds, Nonpenetrating / complications, Wounds, Penetrating / complications, Case Reports, Adult, Diaphragm / surgery, Female, Ghana, Hernia, Diaphragmatic, Traumatic / etiology, Hernia, Diaphragmatic, Traumatic / surgery, Humans, Male, Rupture, Thoracic Injuries / complications, Thoracic Injuries / surgery, Thoracotomy / methods, Wounds, Nonpenetrating / surgery, Wounds, Penetrating / surgery

A rare case series of traumatic right diaphragmatic rupture with hepatothorax in Ghana is reported. The first case involved a middle-aged man who sustained a penetrating chest injury following an unprovoked attack by a wild bull. The second case was a young woman who sustained a blunt chest injury after being knocked down by a moving vehicle whiles crossing the road. Both presented with ruptured right diaphgramatic rupture and had to undergo repair through thoracotomy after stabilization and the two had been well one year after surgery without any complications or sequelae.
Formulation of Trichoderma sp. SL2 inoculants using different carriers for soil treatment in rice seedling growth
Authors: Febri Doni, Anizan Isahak, Che Radziah Che Mohd Zain, Salwati Mohd Ariffin, Wan Nur'ashiqin Wan Mohamad, Wan Mohtar Wan Yusoff
Journal: Springerplus (2014)
Keywords: corn, inoculant carrier, rice growth, sugarcane bagasse, trichoderma sp
MeSH terms: Case Reports

Background:
Trichoderma sp. SL2 has been previously reported to enhance rice germination, vigour, growth and physiological characteristics. The use of Potato Dextrose Agar as carrier of Trichoderma sp. SL2 inoculant is not practical for field application due to its short shelf life and high cost. This study focuses on the use of corn and sugarcane bagasse as potential carriers for Trichoderma sp. SL2 inoculants.
Findings:
A completely randomized design was applied for this study. Trichoderma sp. SL2 suspension mixed with corn and sugarcane bagasse were used as treatment mixture in soil. Growth parameters including rice seedling height, root length, wet weight, leaf number and biomass were measured and compared to control. The results showed that Trichoderma sp. SL2 mixed with corn significantly enhanced rice seedlings root length, wet weight and biomass compared to Trichoderma sp. SL2 mixed with sugarcane bagasse and control.
Conclusion:
Corn can be a potential carrier for Trichoderma spp. inoculants for field application.