OpenMed/multicare-articles huggingface dataset:
Lead poisoning in children: a case report
Authors: Zineb Jouhadi, Dalal Bensabbahia, Fouad Chafiq, Bouchra Oukkache, Nisrine Bennani Guebessi, El Abidi Abdellah, Jilali Najib
Journal: Pan Afr Med J (2016)
Keywords: lead poisoning, children, lead colic
MeSH terms: Abdomen, Acute / diagnosis, Colic / chemically induced, Lead Poisoning / diagnosis, Pica / complications, Case Reports, Abdominal Pain / etiology, Child, Preschool, Humans, Lead / blood, Lead Poisoning / etiology, Male, Paint / adverse effects, Radiography, Abdominal, Lead

Lead colic is a rare cause of abdominal pain. The diagnosis of lead poisoning is most often mentioned in at risk populations (children, psychotic). We report the case of a 2 year old child that was presented for acute abdomen. Abdominal plain radiograph showed multiple intra-colonic metallic particles and suggested lead poisoning diagnosis. Anamnesis found a notion of pica and consumption of peeling paint. Elevated blood lead levels (BLL) confirmed the diagnosis. The lead poisoning is a public health problem especially in children, but its manifestation by a lead colic is rare and could simulate an acute abdomen table.
Vascular complications with injection implants: treatment with hyperbaric chamber
Authors: Danuza Dias Alves, Honório Sampaio Menezes, Roberto Chacur, Rodrigo Cadore Mafaldo, Nívea Maria Bordin da Silva Chacur, Leandro Dias Gomes, Raíssa Nardi, Gabriella Andressa Marchesin de Castro, Vanessa Pletsch Brendler Borges, Manuela Guimarães Dias Gomes
Journal: Case Reports Plast Surg Hand Surg (2021)
Keywords: necrosis, facial filler, treatment in a hyperbaric chamber, vascular occlusion
MeSH terms: Case Reports

Introduction:
The use of facial fillers has increased over the years because they are less invasive and present lower risks and faster results, along with shorter recovery time.
Objective:
This study aimed to analyze the use of hyperbaric oxygen therapy as a possible treatment for vascular complications resulting from facial fillers.
Methodology:
This is a retrospective study of a series of patients treated at with hyperbaric oxygen therapy at the Brazilian Institute for Hyperbaric Oxygen Therapy (Instituto de Oxigenoterapia Hiperbárica do Brasil), after vascular complications from facial fillers.
Conclusion:
The association of oxygen therapy in a hyperbaric chamber with the conventional protocol for treating vascular occlusion from facial filler procedures was found to be effective.
Case Report: Isolated facial and trigeminal nerve palsy without ataxia in anti-GQ1b antibody syndrome secondary to Mycoplasma pneumonia
Authors: Shuwen Deng, Lihong Yin, Wei Lu, Song Ouyang, Weifan Yin
Journal: Front Immunol (2022)
Keywords: guillain-barré syndrome, mycoplasma pneumoniae, anti-gq1b antibody syndrome, facial nerve, trigeminal nerve
MeSH terms: Guillain-Barre Syndrome, Ophthalmoplegia / diagnosis, Ophthalmoplegia / drug therapy, Ophthalmoplegia / etiology, Pneumonia, Mycoplasma / complications, Pneumonia, Mycoplasma / diagnosis, Pneumonia, Mycoplasma / drug therapy, Case Reports, Research Support, Non-U.S. Gov't, Ataxia, Female, Gangliosides, Humans, Trigeminal Nerve, Gangliosides

The presence of anti-GQ1b antibodies in serum or cerebrospinal fluid is a diagnostic indicator of the Miller-Fisher variant of Guillain-Barré syndrome (GBS), whereas anti-GQ1b antibody syndrome is rarely presented as acute bilateral pain in the cheeks and masticatory muscle fatigue without ophthalmoplegia, ataxia, or limb weakness. Here, we report a case of a female patient diagnosed with GBS characterized only by the involvement of the facial and trigeminal nerves who was positive for serum anti-GQ1b antibodies secondary to Mycoplasma pneumoniae infection. The patient was treated with macrolide antibiotics and neurotrophic drugs, and her symptoms were significantly alleviated after 1 month. This case indicates a new clinical presentation of GBS and anti-GQ1b antibody syndrome with a differential diagnosis of multiple cranial nerve damage of which neurological physicians should be aware. Positive anti-GQ1b antibodies secondary to infection were observed in this case, and antibiotic treatment resulted in a favorable prognosis. The specific underlying mechanism requires further investigation.
Fetal hydantoin syndrome and its anaesthetic implications: a case report
Authors: Ranju Singh, Nishant Kumar, Sakshi Arora, Ritu Bhandari, Aruna Jain
Journal: Case Rep Anesthesiol (2012)

Fetal hydantoin syndrome is a rare disorder that is believed to be caused by exposure of a fetus to the anticonvulsant drug phenytoin. The classic features of fetal hydantoin syndrome include craniofacial anomalies, prenatal and postnatal growth deficiencies, underdeveloped nails of the fingers and toes, and mental retardation. Less frequently observed anomalies include cleft lip and palate, microcephaly, ocular defects, cardiovascular anomalies, hypospadias, umbilical and inguinal hernias, and significant developmental delays. Anaesthesia for incidental surgery in such a patient poses unique challenges for the anesthesiologist. We report the successful management of a 4-year-old male child with fetal hydantoin syndrome, cleft palate, spina bifida, atrial septal defect, and dextrocardia for tibialis anterior lengthening under subarachnoid block.
Case report: Resection of a massive primary sacrococcygeal mature teratoma in an adult using 3-dimensional reconstruction and mixed reality technology
Authors: He Zhang, Lu Ji, Jinxin Liu, Shizhe Li, Ting Chen, Jiatong Li, Guanning Shang
Journal: Front Surg (2022)
Keywords: case report, mixed reality, pseudoarthrosis, sacrococcygeal, teratoma, three-dimensional reconstruction (3d reconstruction)
MeSH terms: Case Reports

Introduction:
Teratomas are rare neoplasms that arise from pluripotent germ cells. Sacrococcygeal teratomas are often diagnosed in infants but are rare in adults; a mature teratoma can contain hair, teeth, bony tissue, and other mature tissue types. Herein, we report for the first time a patient with a teratoma containing intact bones that formed a pseudoarthrosis.
Case report:
A 49-year-old woman was admitted to hospital after a massive life-long sciatic tumor had begun to grow larger over the past year. A 16 cm × 25 cm solid mass with a clear boundary was palpable in the sacrococcygeal region. Radiography, computed tomography, and magnetic resonance imaging indicated a sacrococcygeal teratoma, although blood alpha-fetoprotein levels were normal. The teratoma was completely excised using 3-dimensional reconstruction mixed reality (MR) technology with no notable complications. Postoperative pathological examination of the excised lesion confirmed a mature teratoma. Interestingly, two intact irregular bones that formed a pseudoarthrosis were isolated; one was 11 cm and the other 6 cm. The patient is currently healthy and has experienced no recurrences.
Conclusion:
Sacrococcygeal teratomas are rare, especially in adults, and often comprised lots of components, such as fat, bony tissue. However, it's first reported that formation of pseudoarthrosis in this case so far. It is difficult for surgeons to achieve complete excision without complications owing to the complex anatomic structure of the sacrum. The 3-dimensional reconstruction and mixed reality (MR) technology based on computed tomography can provide spatial visualization, which allows surgeons to examine the teratoma at different angles preoperatively. Combining 3-dimensional reconstruction and mixed reality (MR) technology in this case facilitated complete resection and prevented recurrence.
Case report: severe heat stroke with multiple organ dysfunction - a novel intravascular treatment approach
Authors: Gregor Broessner, Ronny Beer, Gerhard Franz, Peter Lackner, Klaus Engelhardt, Christian Brenneis, Bettina Pfausler, Erich Schmutzhard
Journal: Crit Care (2005)
MeSH terms: Body Temperature, Heat Stroke / complications, Multiple Organ Failure / etiology, Case Reports, Adult, Cytokines / blood, Diuresis, Heat Stroke / therapy, Hepatic Encephalopathy / etiology, Hepatic Encephalopathy / therapy, Hot Temperature / adverse effects, Humans, Hypothermia, Induced / instrumentation, Male, Multiple Organ Failure / therapy, Respiratory Insufficiency / etiology, Respiratory Insufficiency / therapy, Rhabdomyolysis / etiology, Rhabdomyolysis / therapy, Cytokines

Introduction:
We report the case of a patient who developed a severe post-exertional heat stroke with consecutive multiple organ dysfunction resistant to conventional antipyretic treatment, necessitating the use of a novel endovascular device to combat hyperthermia and maintain normothermia.
Methods:
A 38-year-old male suffering from severe heat stroke with predominant signs and symptoms of encephalopathy requiring acute admission to an intensive care unit, was admitted to a ten-bed neurological intensive care unit of a tertiary care hospital. The patient developed consecutive multiple organ dysfunction with rhabdomyolysis, and hepatic and respiratory failure. Temperature elevation was resistant to conventional treatment measures. Aggressive intensive care treatment included forced diuresis and endovascular cooling to combat hyperthermia and maintain normothermia.
Results:
Analyses of serum revealed elevation of proinflammatory cytokines (TNF alpha, IL-6), cytokines (IL-2R), anti-inflammatory cytokines (IL-4) and chemokines (IL-8) as well as signs of rhabdomyolysis and hepatic failure. Aggressive intensive care treatment as forced diuresis and endovascular cooling (CoolGard and CoolLine) to combat hyperthermia and maintain normothermia were used successfully to treat this severe heat stroke.
Conclusion:
In this case of severe heat stroke, presenting with multiple organ dysfunction and elevation of cytokines and chemokines, which was resistant to conventional cooling therapies, endovascular cooling may have contributed significantly to the reduction of body temperature and, possibly, avoided a fatal result.
Anastomotic leakage with abscess: Neglected severe complication of bariatric surgery for obesity: A case report
Authors: Qing He, Ning-Ning Yang, Yong-Jiu Xie, Yong-Song Guan
Journal: Int J Surg Case Rep (2019)
Keywords: abscess, anastomotic leakage, bariatric surgery, complication, perioperative diet

Introduction:
Presently, bariatric surgery is a widespread treatment for obesity and its co-morbidities. Comprehensive evidence from outcomes of bariatric surgery supported that the surgery is safe and effective. However, we should be aware of the multiple risks of bariatric surgery, especially the severe infection at the operation site.
Case presentation:
A 30-year-old woman was hospitalized for anastomotic leakage with abscess after laparoscopic sleeve gastrectomy. After 53 days of percutaneous drainage, absolute diet fasting, parenteral nutrition and culture based antibiotics etc., she was discharged for recovery.
Discussion:
Theoretically, malabsorption and early diet will increase the risk of anastomotic leakage, but this problem is seldom to be mentioned in related articles. Moreover, it seems to be common that people received bariatric surgery had a relatively short post-operative stay.
Conclusion:
Essential nutritional support, longer post-operative hospital stay and strict follow-up are necessary to minimize this complication.
Malignant Cerebellar Edema Subsequent to Accidental Prescription Opioid Intoxication in Children
Authors: Daniel Duran, Robert D Messina, Lauren A Beslow, Julio D Montejo, Jason K Karimy, Charuta Gavankar Furey, Alison D Sheridan, Gordon Sze, Yanki Yarman, Michael L DiLuna, Kristopher T Kahle
Journal: Front Neurol (2017)
Keywords: cerebellar edema, opiates, opioid intoxication, pediatric critical care, suboccipital craniectomy
MeSH terms: Case Reports

We present two recent cases of toddlers who developed malignant cerebellar edema subsequent to accidental ingestion of prescription opioids. Both children presented acute neurological decline, hydrocephalus, and tonsillar herniation requiring emergent ventricular drain placement, suboccipital craniectomy, and partial cerebellectomy. Together with several other reports, these cases suggest the existence of an uncommon yet severe syndrome of acute opioid-induced malignant cerebellar edema. We hypothesize that the condition results from a combination of primary opioid receptor-mediated changes in neuronal metabolism that are exacerbated by secondary hypoxic insult. If recognized promptly, this syndrome can be treated with emergent neurosurgical intervention with good clinical outcomes. These cases also illustrate the unintended consequences and innocent victims of the spiraling prescription opioid epidemic, which will likely increase in prevalence. Recognition of this syndrome by clinicians is thus critical.
Case Report: A spinal infection with bilateral psoas abscesses was treated with NPWT to enhance the local infection by increasing the infiltration of neutrophil cells and draining the pus
Authors: Jianhua Li, Zhengqi Chang
Journal: Front Cell Infect Microbiol (2023)
Keywords: bilateral psoas abscess, lateral approach, negative pressure wound therapy (npwt), neutrophil, spinal infections
MeSH terms: Brucellosis, Psoas Abscess / therapy, Case Reports, Research Support, Non-U.S. Gov't, Endothelial Cells, Humans, Neutrophils, Retrospective Studies

Treatment of spinal brucellosis with bilateral psoas abscess is a challenging clinical endeavor. We retrospectively evaluated a case of lumbar infection and bilateral psoas abscess, and was effectively managed through a unilateral extreme lateral approach with the aid of NPWT for bilateral drainage. We hypothesize that NPWT can influence the Piezo1 receptor of neutrophils and further influence the interaction between neutrophils and endothelial cells to promote the clearance of infected lesions, and this phenomenon is also observed in pathological slides. This proves that NPWT can rapidly enhance the recruitment of neutrophils in the infected area and improve the local immune response, and after a year of reassessment and tracking, Bilateral drainage using NPWT via a unilateral Extreme Lateral Approach could acquire satisfactory surgical outcomes, can be used as a treatment modality for lumbar infection with bilateral psoas abscesses.
Malignant Melanocytic Matricoma: A Rare Skin Tumor That Can Clinically Mimic Melanoma
Authors: Layla Tahiri Elousrouti, Imane Fadlallah, Meryem Soughi, Houda Elabbad, Hanane Baybay, Fatima Zahra Mernissi, Hinde Elfatemi, Laila Chbani, Nawal Hammas
Journal: Cureus (2023)
Keywords: beta-catenin antibody, carcinoma, dendritic melanocyte, malignant matricoma, matrical differentiation, skin appendage tumor
MeSH terms: Case Reports

Malignant melanocytic matricoma (MMM) is an extremely rare skin malignant neoplasm composed of epithelial cells with matrical differentiation and dendritic melanocytes. We found only 11 cases reported in the literature to date according to the databases consulted (PubMed/Medline, Scopus, and Web of Science). Here, we report a case of MMM in an 86-year-old woman. A histological examination showed a dermal tumor with a deep infiltrative pattern, without an epidermal connection. On immunohistochemical staining, tumor cells were positive for cytokeratin AE1/AE3, p63, and beta-catenin (nuclear and cytoplasmic staining) and negative for HMB45, Melan-A, S-100 protein, and androgen receptor. Melanic antibodies highlighted scattered dendritic melanocytes in tumor sheets. The findings did not support the diagnosis of melanoma, poorly differentiated sebaceous carcinoma, and basal cell carcinoma, but supported the diagnosis of MMM.
3D Reconstruction Model of an Extra-Abdominal Desmoid Tumor: A Case Study
Authors: Franco Marinozzi, Francesco Carleo, Simone Novelli, Marco Di Martino, Giuseppe Cardillo, Lea Petrella, Fabiano Bini
Journal: Front Bioeng Biotechnol (2020)
Keywords: 3d printing, 3d reconstruction, desmoid tumor, diagnostic imaging, thoracic surgery
MeSH terms: Case Reports

In recent years, three-dimensional reconstruction (3DR) models have become a standard tool in several medical fields such as education, surgical training simulation, patient-doctor communication, and surgical planning. Postoncologic reconstructive surgery in thoracic diseases might benefit from 3DR models; however, limited data on this application have been published worldwide. In this paper, the aim was to report our experience with 3DR modeling to determine resection and plan the surgical reconstruction in a patient with a desmoid tumor of the chest wall. For a better understanding of the case study, we describe all the steps from acquiring computed tomography (CT) scans to the final 3D rendering. A 68-year-old, non-smoking man presented at our outpatient department with painless swelling of the right anterobasal chest wall. A thorax-abdomen-brain CT scan revealed homogenous solid tissue with a dense mass measuring 80 mm × 62 mm. The final 3D model was evaluated by the surgical team (three medical doctors), who found the model to be powerful. Based on the results and the accuracy of the model, the multidisciplinary team decided that the tumor was resectable. Consequently, a surgical plan based on the 3D model was developed to perform chest wall reconstruction after radical resection. The patient underwent right anterolateral thoracotomy at the seventh intercostal space, which confirmed the CT scan findings and revealed infiltration of the serratus muscle and medial portion of the diaphragm. A radical tumor en bloc resection with chest wall and diaphragm resection was performed. The full-thickness chest wall and diaphragm defects were reconstructed using two separate biological patches of a porcine dermal collagen implant (Permacol™ Surgical Implant). Postoperative X-ray revealed unremarkable findings; the patient had an uneventful recovery and was discharged 6 days after surgery. This case study illustrates that 3DR models enable a personalized approach to the treatment of desmoid tumors. Therefore, this approach should be developed further and studied systematically.