OpenMed/multicare-articles huggingface dataset:
Deltamethrin Poisoning Mimicking Organophosphate Poisoning: A Case Report
Authors: Waseem M Ilyas, Gajanan Chavan, Charuta Gadkari
Journal: Cureus (2023)
Keywords: atropine challenge test, deltamethrin, deltamethrin poisoning, fasciculations, insecticide poisoning, organophosphate, organophosphate poisoning, smell of organophosphate, toxicology and envenomation, unknown poisoning
MeSH terms: Case Reports

Deltamethrin is a newer class of insecticide used on crops, pets, and livestock, in home pest control, and malaria vector control belonging to the synthetic pyrethroid group, which is being promoted in the place of organophosphate compounds due to the harmful and persistent effects of the latter. Unfortunately, as its usage increased, so has the number of poisoning cases associated with deltamethrin. Fortunately, the mortality in deltamethrin poisoning cases is low. However, deltamethrin poisoning causes signs and symptoms similar to the clinical features of organophosphate poisoning. This case report is of a 20-year-old man who consumed an unknown substance in a suicidal attempt and presented with clinical signs of organophosphate toxicity. Later the compound was identified as deltamethrin. This case report adds to the medical literature on deltamethrin poisoning. It showed that apart from the similarity in their clinical features in toxicity, deltamethrin can even give a positive result on atropine challenge tests like organophosphate and that the fasciculations induced by deltamethrin may be temporary. This case report will also benefit the clinician in unknown compound poisoning cases as it shows that the clinician can suspect deltamethrin toxicity alongside organophosphate toxicity in the differential diagnosis when the atropine challenge test gives a positive result.
Piperacillin/Tazobactam as Cause of Acute Generalized Exanthematous Pustulosis
Authors: Aikaterini Kyriakou, Sofia-Chrysovalantou Zagalioti, Aikaterini Patsatsi, Nikiforos Galanis, Elizabeth Lazaridou
Journal: Case Rep Dermatol Med (2019)
MeSH terms: Case Reports

Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous adverse reaction mainly attributed to antibiotics. It is characterized by numerous, nonfollicular, sterile pustules, arising on an exanthematous and edematous base. It is a serious adverse reaction accompanied by fever and leukocytosis. Piperacillin/tazobactam is indicated for the treatment of patients with moderate to severe infections. Herein is reported a case of AGEP caused by piperacillin/tazobactam. A 78-year-old woman with metastatic breast cancer was presented to the emergency department reporting fever and groin pain. The laboratory analysis and more specifically urine cultivation showed a urinary tract infection by E. coli with sensitivity to piperacillin/tazobactam. She had no known allergies. She was started on intravenous piperacillin/tazobactam; she improved clinically on the second day, but on the fourth day of intravenous therapy, she developed extensive pustular rash on the folds and anterior proximal thighs, accompanied by fever and neutrophilia. Piperacillin/tazobactam administration was interrupted and she was given prednisolone for ten days. The patient improved clinically and her laboratory tests returned to normal after two weeks. AGEP is an uncommon side effect of piperacillin/tazobactam treatment and there are few cases reported.
Case Report: The success of face analysis technology in extremely rare genetic diseases in Korea: Tatton-Brown-Rahman syndrome and Say-Barber -Biesecker-Young-Simpson variant of ohdo syndrome
Authors: Sunha Park, Jaewon Kim, Tae-Young Song, Dae-Hyun Jang
Journal: Front Genet (2022)
Keywords: sbbyss, artificial intelligence, deep learning, rare diseases, tatton-brown-rahman syndrome
MeSH terms: Case Reports

Tatton-Brown-Rahman syndrome (TBRS) and Say-Barber-Biesecker- Young-Simpson variant of Ohdo syndrome (SBBYSS) are extremely rare genetic disorders with less than 100 reported cases. Patients with these disorders exhibit a characteristic facial dysmorphism: TBRS is characterized by a round face, a straight and thick eyebrow, and prominent maxillary incisors, whereas SBBYSS is characterized by mask-like facies, blepharophimosis, and ptosis. The usefulness of Face2Gene as a tool for the identification of dysmorphology syndromes is discussed, because, in these patients, it suggested TBRS and SBBYSS within the top five candidate disorders. Face2Gene is useful for the diagnosis of extremely rare diseases in Korean patients, suggesting the possibility of expanding its clinical applications.
Left Gastric Artery Pseudoaneurysm Complicating Chronic Calcifying Pancreatitis in a Child
Authors: Md S Ahmad, Biswajit Sahoo, Kanishka Das, Akash Pati
Journal: Cureus (2023)
Keywords: artery pseudoaneurysm, interventional radiology guided embolization, left gastric artery embolization, treatment of chronic pancreatitis, vascular complication
MeSH terms: Case Reports

A left gastric artery pseudoaneurysm is a rare complication of pancreatitis and is associated with significant morbidity and mortality. We report a 14-year-old male with severe abdominal pain and a palpable upper abdominal mass, earlier diagnosed as chronic idiopathic calcifying pancreatitis, and awaiting surgical intervention. Computed tomography showed a pseudocyst and a pseudoaneurysm in the lesser sac near the left gastric artery. The patient underwent successful angiographic coiling of the left gastric artery and definitive pancreatic surgery weeks thereafter. The early detection and interventional radiologic management of the vascular complication averted a life-threatening hemorrhage without emergency surgery in a pediatric patient.
Transformation of a prostatic adenocarcinoma into squamous cell carcinoma after luteinizing hormone-releasing hormone (LHRH) agonist and radiotherapy treatment
Authors: Hamza Ichaoui, Sonia Ben Nasr, Faten Gargouri, Aref Zribi, Amine Hermi, Sana Fendri, Mehdi Balti, Jihen Ayari, Ramzi Khiari, Issam Msakni, Nada Mansouri, Samir Ghozzi, Abderrazek Haddaoui
Journal: Pan Afr Med J (2019)
Keywords: prostate, hormonotherapy, squamous cell carcinoma
MeSH terms: Adenocarcinoma / pathology, Carcinoma, Squamous Cell / pathology, Prostatic Neoplasms / pathology, Case Reports, Adenocarcinoma / therapy, Aged, Antineoplastic Agents, Hormonal / administration & dosage, Carcinoma, Squamous Cell / therapy, Combined Modality Therapy, Gonadotropin-Releasing Hormone / agonists, Humans, Male, Neoplasm Recurrence, Local, Prostatectomy, Prostatic Neoplasms / therapy, Triptorelin Pamoate / administration & dosage, Antineoplastic Agents, Hormonal, Triptorelin Pamoate, Gonadotropin-Releasing Hormone

Squamous cell carcinoma of the prostate is rare and represents 0.5% to 1% of prostatic carcinomas. Transformation of prostatic adenocarcinoma into squamous cell carcinoma after LH-RH agonist intake has been reported in only 8 cases in the literature. To our knowledge, our case is the second pure squamous cell carcinoma observed after hormonotherapy and radiotherapy. We reported a case of a patient with prostatic adenocarcinoma treated by radical prostatectomy followed by radiotherapy. Eleven years later, he had a vesical recurrence of prostatic adenocarcinoma. Our patient had an endoscopic resection followed by injections of Triptorelin. Six months later, he developed a local recurrence of a squamous cell carcinoma.
Steroid Responsive Mononeuritis Multiplex in the Cronkhite-Canada Syndrome
Authors: Y L Lo, K H Lim, X M Cheng, S Mesenas
Journal: Front Neurol (2016)
Keywords: cronkhite–canada syndrome, autoimmune, mononeuritis multiplex, neuropathy, steroids
MeSH terms: Case Reports

The Cronkhite-Canada syndrome (CCS) is a rare disorder of unknown origin characterized by generalized gastrointestinal polyposis, alopecia, hyperpigmentation, and onychodystrophy. We report a case of CCS with concomitant presentation of mononeuritis multiplex. The electrophysiological findings and steroid responsiveness suggests presence of an autoimmune mechanism.
Kawasaki disease presenting with intussusception: a case report
Authors: Rumana N Hussain, Gary Ruiz
Journal: Ital J Pediatr (2010)
MeSH terms: Intussusception / etiology, Mucocutaneous Lymph Node Syndrome / complications, Case Reports, Anti-Inflammatory Agents, Non-Steroidal / administration & dosage, Anti-Inflammatory Agents, Non-Steroidal / therapeutic use, Aspirin / administration & dosage, Aspirin / therapeutic use, Child, Preschool, Dose-Response Relationship, Drug, Drug Therapy, Combination, Enema, Follow-Up Studies, Humans, Immunoglobulins, Intravenous / therapeutic use, Immunologic Factors / therapeutic use, Insufflation / methods, Intussusception / diagnosis, Intussusception / therapy, Male, Mucocutaneous Lymph Node Syndrome / diagnosis, Mucocutaneous Lymph Node Syndrome / drug therapy, Anti-Inflammatory Agents, Non-Steroidal, Immunoglobulins, Intravenous, Immunologic Factors, Aspirin

A 3 yr old boy presented with abdominal pain, fever and red jelly stools. Intussusception was diagnosed and effectively reduced with air insufflation. However, despite an improvement in his clinical condition, the child remained febrile and miserable; 5 days later he developed characteristic signs of Kawasaki disease and was treated with intravenous immunoglobulin and high dose aspirin with good results. Intussusception prior to the typical features of Kawasaki disease has not been described previously in the English literature. This case illustrates a novel presentation of Kawasaki disease.
Diagnosis of Cryptococcosis and Prevention of Cryptococcal Meningitis Using a Novel Point-of-Care Lateral Flow Assay
Authors: Ashar Dhana
Journal: Case Rep Med (2013)

Despite access to antiretroviral therapy, mortality from cryptococcal meningitis (CM) is high among persons with advanced HIV infection in sub-Saharan Africa. Cryptococcal antigen (CrAg) is present several weeks to months before the onset of symptoms of meningitis and can be screened to prevent life threatening meningitis. Recently, the World Health Organisation recommended that a new rapid CrAg lateral flow ''dipstick" assay (LFA) is to be used to screen HIV-infected persons with CD4 counts of less than 100 cells/µL. In this paper, we describe two cases of cryptococcosis with differing outcomes. In the first case, the new CrAg LFA was used as part of a screen and preemptive treatment strategy to prevent CM. In the second case, our patient had no access to the CrAg LFA and subsequently developed life threatening meningitis. To the best of our knowledge, this is the first case report of cryptococcosis diagnosed using this novel assay.
Methicillin-Sensitive Staphylococcus aureus Suppurative Thyroiditis with Thyrotoxicosis
Authors: Sha Yan, Laryssa Patti
Journal: Case Rep Emerg Med (2017)
MeSH terms: Case Reports

Intravenous drug use (IVDU) can lead to numerous complications from skin abscesses to bacteremia to endocarditis. Here, we present a rare case of acute suppurative thyroiditis as a complication of IVDU, in which a 26-year-old female with a past medical history of IVDU presented to the emergency department for evaluation of a large right sided neck mass. On exam, she had signs of sepsis and thyrotoxicosis. Fine needle aspiration confirmed suppurative thyroiditis. Blood cultures and culture from fine needle aspiration grew Staphylococcus aureus. Patient was treated with 2 weeks of intravenous antibiotics with good resolution of her symptoms.
Cutaneous Metastasis in the Setting of Both Colon and Breast Primary Malignancies
Authors: Mary Junak, Hunter Jecius, Jennifer Erdrich
Journal: Case Rep Gastrointest Med (2020)
MeSH terms: Case Reports

Colorectal cancer (CRC) is the third most diagnosed cancer in the United States, and many patients unfortunately have metastases at the time of their diagnosis. Cutaneous metastases of CRC have been reported in few journals and primarily as case reports due to their rarity. Here, we present the case of an 83-year-old woman with recently resected colon cancer, T4aN1bMx stage IIIB. She presented to our clinic for evaluation of a right midback mass, and a punch biopsy revealed dermal involvement by invasive, poorly differentiated carcinoma with epidermoid features. The mass was excised, and we ordered a PET scan in search of the primary tumor, which at that time was suspected to be of skin cancer origin. Surprisingly, this revealed a second malignancy triple-negative invasive ductal carcinoma of the left breast. The back mass stained positive for CK20, which was compatible with a metastasis from a colonic primary. After initially declining adjuvant therapy, the patient completed one cycle of capecitabine and oxaliplatin, which she tolerated poorly. She continued to further decline, developed widespread cutaneous metastases, and went home on hospice. Cutaneous lesions are an exceedingly rare site of metastasis for colon adenocarcinoma, and their clinical presentation can vary widely. It is important for providers to investigate any new skin lesion in a patient with a recent or remote history of malignancy, even if there were no sites of distant metastasis at initial diagnosis.
Lineage switch from lymphoma to myeloid neoplasms: First case series from a single institution
Authors: Wenjuan Yang, Shuangfeng Xie, Yiqing Li, Jieyu Wang, Jie Xiao, Kezhi Huang, Xiuju Wang, Yudan Wu, Liping Ma, Danian Nie
Journal: Open Med (Wars) (2022)
Keywords: lineage switch, lymphoma, myeloid neoplasms
MeSH terms: Case Reports

Lymphoma relapse is very common in clinical work, but lineage switch at relapse is rare. Although some cases have reported acute lymphocytic leukemia (ALL) switch to acute myeloid leukemia (AML) or myeloid sarcoma upon relapse, phenotype switch seldom occurs in other types of lymphoma. Here we report six cases with lineage switch from lymphoma to myeloid neoplasms. In our cohort, three cases were mantle cell lymphoma (MCL), and the other three cases were T-cell lymphoblastic lymphoma (T-LBL), B-cell lymphoblastic lymphoma (B-LBL), and diffuse large B-cell lymphoma (DLBCL) at the initial diagnosis. When linage switch occurred, most cases were AML M5 phenotypes, and only one case was myelodysplastic syndrome (MDS) phenotype. 11q23/mixed-lineage leukemia (MLL) rearrangement was negative in all cases. Although intensive therapy and stem cell transplantation have been applied in most cases, the poor outcome cannot be reversed. Therefore, we found that lineage switch could occur not only from ALL to AML or vice versa, but also from MCL or DLBCL to AML. Moreover, the incidence of MLL rearrangement in lineage switch is lower in adult hematologic malignancies as compared with pediatric patients.
Theta-Burst Stimulation for Auditory-Verbal Hallucination in Very-Late-Onset Schizophrenia-Like Psychosis-A Functional Magnetic Resonance Imaging Case Study
Authors: Rebecca Zöllner, Anne-Friederike Hübener, Udo Dannlowski, Tilo Kircher, Jens Sommer, Maxim Zavorotnyy
Journal: Front Psychiatry (2020)
Keywords: auditory processing, auditory verbal hallucination, brain stimulation, elderly, functional mri, theta-burst stimulation, very-late-onset schizophrenia-like psychosis
MeSH terms: Case Reports

Background:
Treating very-late-onset (>60 years) schizophrenia-like psychosis (VLOSLP) is challenging. Age-related factors in elderly individuals (e.g., metabolism, medication side effects, drug-interaction, somatic morbidity) may adversely affect treatment. Novel therapeutic approaches are needed to ensure the favorable therapeutic outcome in geriatric patients. Previously, theta-burst stimulation (TBS), a novel form of repetitive transcranial magnetic stimulation, was reported being beneficial in the treatment for auditory-verbal hallucination (AVH) in young and middle-aged schizophrenia (SZ) patients.
Case presentation:
Here we present a case of a male patient aged 73. His first psychotic episode manifested with paranoid delusions, auditory-verbal and tactile hallucinations at the age of 66, and first remitted following a second-generation antipsychotics (SGA). Years later, after a relapse the AVH did not respond to previously effective olanzapine, whereas its augmentation with an inhibitory TBS over the left temporal lobe led to a stable remission. During his second relapse, TBS was again capable of facilitating therapeutic action of SGA in the same patient. Extending to our clinical observation, a series of functional MRI scans employing a tonal activation paradigm depicted altered auditory processing during AVH as well as brain activation change during remission.
Conclusions:
The current case might indicate to favorable effects of combining conventional medicament therapy and non-invasive brain stimulation techniques for elderly patients. Also, we speculate that despite obviously distinct etiologies, the present functional imaging and clinical observation may also demonstrate a possible common pathophysiological pathway underlying AVH in VLOSLP and SZ.
Abdominal wall schwannoma: a case report
Authors: Mohamed Tarchouli, Mohamed Essarghini, Ouadie Qamouss, Abdennasser El Kharras, Ahmed Bounaim
Journal: Gastroenterol Hepatol Bed Bench (2020)
Keywords: abdominal wall, peripheral nerve sheath tumors, schwannoma
MeSH terms: Case Reports

Schwannomas or neurilemmomas are benign and slow-growing tumors that arise exclusively from Schwann cells in peripheral nerve sheaths. These neoplasms theoretically can occur anywhere in the body, but they most frequently affect extremities, as well as head and neck region. However, their presentation in the abdominal wall is extremely rare and only few cases have been reported in the literature. Subcutaneous lesions may be asymptomatic and only incidentally discovered upon physical examination or imaging. However, occasionally they induce mass effects on surrounding large nerves. We present the case of a 34-year-old man with abdominal wall pain localized in the right iliac fossa and palpable subcutaneous mass. Ultrasound and CT scan revealed a solid well-defined mass of the abdominal wall. Following surgical excision under general anesthesia, histological examination was consistent with the diagnosis of benign schwannoma.
Is there a biological basis for treatment of fibrodysplasia ossificans progressiva with rosiglitazone? Potential benefits and undesired effects
Authors: Renata Bocciardi, Roberto Ravazzolo
Journal: PPAR Res (2010)

Thiazolidinediones (TZDs), among which Rosiglitazone, are known agonists of the peroxisome-proliferator-activated receptor gamma (PPARgamma) commonly used for treatment of hyperglycemia. A recently published article describing a case report on a patient affected by Fibrodysplasia Ossificans Progressiva (FOP) treated with Rosiglitazone has prompted interest for careful analysis of the rational basis of such treatment. This article reviews the effects of PPARgamma agonists in relationship with various pathogenic steps that occur during the course of FOP by reviewing the particularly rich literature on the effects of Rosiglitazone, to underscore their relevance to FOP and to consider possible adverse effects.
The New England 4G framework for the treatment of a common health concerns: a gambling case analysis
Authors: Barry Tolchard, Cynthia M Stuhlmiller
Journal: Asian J Gambl Issues Public Health (2016)
Keywords: cognitive behavioral therapy, problem gambling, rural health, self-help

Approaches using self-help have proved successful at treating a range of mental and physical conditions. Guidance by a trained worker enhances the effects of self-help materials, in particular those based on Cognitive-Behavior Therapy. In the United Kingdom, the Improving Access to Psychological Therapies (IAPT) program was introduced to provide better outcomes for people experiencing mild or moderate anxiety and depression. This stepped care approach included low intensity, guided self-help offered by a newly trained workforce of Psychological Wellbeing Workers. The IAPT program has been extensively evaluated and shown to be cost effective and leads to positive treatment outcomes. This paper describes how the IAPT model has been adapted for use in Australia with gamblers. Two case studies illustrate the application of this guided approach to systematically accessing existing self-help treatments for problem gamblers. Assessment information is gathered, before a plan of action, including a problem statement and achievable goals, is agreed upon by the worker and the person with the gambling problem. The worker then gives the person options based on self-help CBT interventions and, once an option has been chosen, the worker guides the person as they work through various activities. The benefits of this approach are discussed.
Delayed Infection of a Lymphocele following RARP in a Patient with Nonspecific Symptoms
Authors: Tomoki Taniguchi, Yoshito Takahashi, Mitsuhiro Taniguchi, Toru Yamada, Kenichiro Ishida
Journal: Case Rep Urol (2017)
MeSH terms: Case Reports

Pelvic lymphoceles are an infrequent complication after pelvic surgery and develop shortly after the surgery in most cases. We experienced a case of delayed infection of a lymphocele 6 months after robot-assisted radical prostatectomy (RARP) and pelvic lymphadenectomy. In this case, antimicrobial chemotherapy and percutaneous drainage were effective, and there was no recurrence of the disease. Most urologists do not recognize that infected lymphoceles can develop a long time after surgery; thus, infected lymphoceles should be kept in mind in patients with nonspecific infectious symptoms, regardless of the length of time after surgery.
Broken piece of silicone suction catheter in upper alimentary tract of a neonate
Authors: Bilal Mirza, Muhammad Saleem, Afzal Sheikh
Journal: APSP J Case Rep (2010)
Keywords: esophageal foreign body, laryngoscopy, neonate
MeSH terms: Case Reports

Esophageal foreign bodies (FB) are common in adults and children. These are rarely reported in infants and neonates. A 2-day-old newborn was referred to our hospital with history of accidental intrusion of soft silicone suction catheter into the upper gastrointestinal tract (GIT). X-ray chest and abdomen confirmed the presence of suction tube in esophagus and stomach. The suction catheter was retrieved successfully at direct laryngoscopy.
A Case of Delayed Hepatic Injury Associated with Teriflunomide Use as Assessed for Causality Using the Updated RUCAM
Authors: Riana Wurzburger
Journal: Case Reports Hepatol (2022)
MeSH terms: Case Reports

Teriflunomide is a pyrimidine synthesis inhibitor used in the treatment of multiple sclerosis that has in rare instances been associated with liver toxicity, though there are few documented cases. Here, we report a case of probable teriflunomide-induced liver injury as assessed for causality using the updated RUCAM. The liver injury occurred approximately nine months after teriflunomide initiation and improved with discontinuation of the drug and treatment with cholestyramine.