OpenMed/multicare-articles huggingface dataset:
Treatment of an Esophageal Stricture in a 1-Month-Old Miniature Shetland Colt
Authors: P Nijdam, C Elmas, M C Fugazzola
Journal: Case Rep Vet Med (2017)
MeSH terms: Case Reports

A 1-month-old Miniature Shetland colt was presented to the Burg Müggenhausen Equine Clinic. Primary complaints were regurgitation of milk, bilateral white nasal discharge, and weakness. Physical examination, endoscopy of the esophagus, and contrast radiography led to the diagnosis of an esophageal stricture and aspiration pneumonia. Surgical treatment by means of an esophagomyotomy was performed. The foal improved only temporarily and multiple sessions of endoscopic balloon dilation of the esophagus were performed afterwards. 12 months after the final treatment the foal was healthy and had no complaints regarding esophageal function.
Bilateral dentigerous cyst in a non-syndromic patient: Report of an unusual case with review of the literature
Authors: Avinash Tamgadge, Sandhya Tamgadge, Daivat Bhatt, Sudhir Bhalerao, Treville Pereira, Mukul Padhye
Journal: J Oral Maxillofac Pathol (2011)
Keywords: bilateral dentigerous cyst, non-syndromic, syndromic
MeSH terms: Case Reports

Dentigerous cysts are the most common developmental cysts of the jaws, most frequently associated with impacted mandibular third molar teeth and impacted canines. Bilateral dentigerous cysts are rare and occur typically in association with a developmental syndrome. The occurrence of bilateral dentigerous cysts is rare and, to date, only 21 cases have been reported in literature till 2009. Here, we report a case of bilateral dentigerous cysts in maxillae of non-syndromic 10-year-old patient with brief review of literature.
Management of tethered cord syndrome in adults: a case report in Cameroon
Authors: Mathieu Motah, Felix Uduma, Aurélien Ndoumbe, Mireille Georgette Moumi, Vincent de Paul Djientcheu
Journal: Pan Afr Med J (2014)
Keywords: tethered cord syndrome, adult, surgery
MeSH terms: Magnetic Resonance Imaging / methods, Microsurgery / methods, Neural Tube Defects / surgery, Case Reports, Cameroon, Fecal Incontinence / etiology, Fecal Incontinence / surgery, Female, Humans, Neural Tube Defects / diagnosis, Neural Tube Defects / physiopathology, Treatment Outcome, Urinary Incontinence / etiology, Urinary Incontinence / surgery, Young Adult

Tethered cord syndrome (TCS) is spinal cord fixation from multiple pathological entities. No case of TCShas been reported in our region. The goal of this case report was to describe a TCS managed at the Douala General hospital. Mrs. EEL, 23 year old consulted in 2012 for urinary and fecal incontinence. She had a past history of a spina bifida at birth operated on day two of life. On admission, lumbar MRI showed an abnormally low lying conus medullaris ending at S. Microsurgery permitted to gradually detach the spinal cord from subcutaneous tissue and carefully free the spinal nerves. A 12 months post-surgery, the patient could control defecation, and achieve proper micturition. TCS should also be ruled out in patients who present with urinary and ano-rectal symptoms especially of childhood onset; more so with present day availability of modern radiological tools like MRI.
A Rare Case of Metastasis to the Thyroid Gland from Renal Clear Cell Carcinoma 11 Years after Nephrectomy and Concurrent Primary Esophageal Carcinoma
Authors: Mohammad Saud Khan, Veena Balakrishnan Iyer, Neha Varshney
Journal: Case Rep Oncol Med (2018)
MeSH terms: Case Reports

Renal cell carcinoma is known to cause metastasis to unusual sites, which can be both synchronous or metachronous. Thyroid gland is a rare site for metastasis, but when it occurs, renal cell carcinoma is the most common primary neoplasm. We report the case of a 81-year-old female patient who had a significant medical history of right clear cell renal carcinoma with adrenal metastasis. She underwent right radical nephrectomy and adrenalectomy followed by radiofrequency ablation of left adrenal metastasis and systemic chemotherapy with sunitinib. Eleven years later, she presented with dysphagia and was found to have distal esophageal adenocarcinoma. On imaging, there was incidental detection of a left renal mass lesion and a right thyroid nodule, which on histopathology and immunohistochemistry were confirmed to be clear cell carcinoma of renal origin.
Successful Endovascular Repair of a Ruptured Popliteal Artery Aneurysm: A Case Report and Literature Review
Authors: Duncan Muir, Sachin R Kulkarni
Journal: Case Rep Vasc Med (2020)
MeSH terms: Case Reports

Introduction. It is rare for a popliteal artery aneurysm (PAA) to present with rupture. This case reports a longer-term success in the management of a large ruptured popliteal artery aneurysm with an endovascular approach, with a literature review of management of such cases. Case Report. An 80-year-old man presented to the accident and emergency department with pain and swelling behind the left knee and at the back of the thigh. An ultrasound scan and subsequent CT angiogram revealed a large 9.4 cm ruptured PAA. The patient had significant comorbidities deeming him unfit for a major surgical intervention of drainage of haematoma and exclusion bypass. Therefore, he underwent urgent endovascular treatment of the ruptured PAA with a covered stent graft. A follow-up duplex scan at 1 year showed a patent stent with no evidence of endoleak, and the patient remained asymptomatic. A clinical follow-up at 18- and 24-month postprocedure showed a patent stent graft and complete resolution of haematoma. Conclusion. Whilst open repair with exclusion bypass may still be a treatment of choice, an endovascular approach is both safe and effective in the management of a ruptured PAA in an unfit patient with an acceptable longer-term outcome.
Case Report: ST-Segment Elevation in a Man With Acute Pericarditis
Authors: Yi-Ming Li, Yu-Heng Jia, Jiay-Yu Tsauo, Si Wang, Yong Peng
Journal: Front Cardiovasc Med (2020)
Keywords: ecg, stemi, acute pericarditis, esophageal perforation, purulent pericarditis
MeSH terms: Case Reports

Background: Acute pericarditis is a rapid inflammatory condition of the pericardium with both infectious and non-infectious etiology. Most acute pericarditis is self-limited, with a small portion evolving rapidly. The definitive diagnosis of acute pericarditis often requires detailed physical examination, ECG, echocardiography, blood analysis and chest X-ray. It's usually challenging to distinguish acute pericarditis from ST-elevated myocardial infarction (STEMI) due to the similar ECG characteristics (ST segment change). Here we present a case of purulent pericarditis probably caused by esophageal perforation. Case: A 52 year-old male presented with chest pain and dyspnea for 16 h. ST-segment elevation and positive cardiac markers lead to the initial diagnosis of ST-elevated myocardial infarction. Coronary angiography demonstrated normal coronary artery, while transthoracic echocardiography (TTE) showed massive pericardial effusion. Then, pericardiocentesis was performed with 250 ml of yellowish-green pus-like fluid extracted. A detailed history examination revealed a week history of possible esophageal perforation caused by a fishbone. And a further computed tomography (CT) demonstrated the presence of pneumomediastinum, and effusions in mediastinum, which lead to the diagnosis of purulent pericarditis. However, the patient's family refused further treatment and the patient died soon after discharge. Conclusion: The differential diagnosis of chest pain should include acute pericarditis, which can be equally critical and fatal. And it's important to note the peculiar characteristics of acute pericarditis, which include concave and diffused ST-segment elevation, PR segment depression, and the ratio of ST-segment elevation to T wave >0.24 in lead V6. Moreover, comprehensive medical history and physical examination are crucial to the differential diagnosis of chest pain patients.
Manifestation of paroxysmal nocturnal hemoglobinuria as repeated acute kidney injury
Authors: Manish R Balwani, Vivek B Kute, Pankaj R Shah, Maulin Shah, Umesh Varyani, Hargovind L Trivedi
Journal: J Nephropharmacol (2015)
Keywords: acute kidney injury, flow cytometry, hemodialysis, hemolytic anemia, paroxysmal nocturnal hemoglobinuria
MeSH terms: Case Reports

The triad of hemolytic anemia, pancytopenia, and thrombosis makes paroxysmal nocturnal hemoglobinuria (PNH) a truly unique clinical syndrome. Intravascular hemolysis in PNH can lead to a severe hemolytic episode with massive hemoglobinuria which can cause acute kidney injury (AKI) probably from acute tubular necrosis (ATN). A 15 -year-old girl was admitted with history of fever, diarrhea, vomiting followed by decreased urine output since 3 days. Urinalysis showed nil protein, no red blood cells (RBCs) on microscopy. Plasma hemoglobin level, total leukocyte count, platelet count, and serum creatinine were 6.5 gm/dl, 6440/μl, 205 000/μl, and 3.1 mg/dl, respectively. She received 3 units of packed red blood cells and the patient was discharged with normal renal function test with a diagnosis of acute gastroenteritis with recovered AKI. After 8 months she again had fever, vomiting, nausea with decreased urine output since 3 days. Laboratory investigations showed hemoglobin - 5.5 gm/dl, total leukocyte count - 1550/ μl, platelet count - 165000/μl, and serum creatinine - 4.89 mg/dl. Serum LDH level was 2188 U/l. She was managed conservatively with steroids, antibiotics and she recovered her kidney functions to normal in a week. Presentation of repeated AKI with hemolytic anemia in a short span after fever led us to perform flow cytometric analysis of peripheral blood granulocytes which revealed the presence of PNH clone. PNH may present with renal disease and anemia only even without classical history of hematuria or venous thrombosis. Thus it needs high index of suspicion as early diagnosis and treatment will help in preventing repeated episodes of AKI and thus chronic kidney disease.
An Unusual Presentation of Merkel Cell Carcinoma in a HIV Patient: A Case Report and Literature Review
Authors: Preethi Ramachandran, Burak Erdinc, Vladimir Gotlieb
Journal: J Investig Med High Impact Case Rep (2019)
Keywords: hiv, merkel cell cancer, metastatic disease, subcutaneous nodule
MeSH terms: Carcinoma, Merkel Cell / diagnosis, Facial Neoplasms / diagnosis, HIV Infections / complications, Skin Neoplasms / diagnosis, Case Reports, Review, Carcinoma, Merkel Cell / complications, Carcinoma, Merkel Cell / therapy, Combined Modality Therapy, Facial Neoplasms / complications, Facial Neoplasms / therapy, Forehead, Humans, Immunotherapy, Magnetic Resonance Imaging, Male, Middle Aged, Skin Neoplasms / complications, Skin Neoplasms / therapy, Tomography, X-Ray Computed

Merkel cell carcinoma (MCC) is a rare, rapidly growing, aggressive neuroendocrine skin cancer that generally arises on sun-exposed areas of body such as head, neck, upper limbs, and shoulders of people with light complexity. Typically, MCC presents as shiny, flesh-colored or bluish-red, intracutaneous nodule, possibly with ulceration or crusting. In most of the cases, there is an association with Merkel cell polyomavirus. Even though these are very aggressive tumors, early detection and treatment has always given favorable outcome. There seems to be no consensus in definite prognostic markers, and advanced stages have the worst outcome even with treatment. There has been a recent trend in using PD-I/PD-L1 target therapy rather than chemotherapy in these cancers and have shown to improve survival by many months. In this article, we report a very unusual presentation of MCC first found on left frontoparietal skull as an 8-cm diameter fixed, subcutaneous mass without any typical features of MCC and was found to have metastatic spread to lung and liver. The patient was treated with palliative radiotherapy to brain and chemotherapy with cisplatin/etoposide with addition of immunotherapy later.
Engaging Posterior Capitellum Fracture and Elbow Posterolateral Rotatory Instability: Is It Always Necessary to Treat the Bone Defect?
Authors: Juan M Patiño, Juan M Torres Moirano
Journal: Case Rep Orthop (2020)
MeSH terms: Case Reports

Case:
We present a 23-year-old male with 7 episodes of left elbow dislocation during a two-year period. He had a positive pivot shift test with engaging. The original treatment plan included lateral ulnar collateral ligament reconstruction and eventually bone defect grafting and osteosynthesis. However, a bone graft was not performed. After 2 years of follow-up, the DASH score was 3.3. The Mayo Score was 90.
Conclusion:
Posterolateral instability associated with an engaging bone defect, in every elbow extension and pivot shift test, was not found in the literature. The capitellum defects are associated with PLRI and make it worse. Bone reconstruction may not be indicated.
Computed Tomographic Features in a Case of Bilateral Neoplastic Cryptorchidism with Suspected Torsion in a Dog
Authors: Scott Stokowski, Jeffrey Ruth, Otto Lanz, Vincent Ziglioli
Journal: Front Vet Sci (2016)
Keywords: sertoli cell tumor, computed tomography, cryptorchid, torsion, whirl sign
MeSH terms: Case Reports

An 11-year-old male German Shepherd dog presented for inappetence and weight loss. Physical examination and initial bloodwork revealed palpable abdominal masses, mild non-regenerative anemia, and thrombocytopenia. Survey radiography and abdominal ultrasonography confirmed the presence of bilateral abdominal masses and lymphadenopathy. Contrast-enhanced computed tomography (CT) was performed in order to further investigate the origin of the intraabdominal masses, confirming two enlarged cryptorchid testes, one of which had an associated CT "whirl sign." Histopathology of the testes and lymph nodes revealed bilateral malignant Sertoli cell tumors and seminomas with lymph node metastasis of both neoplasms. The purpose of this case report is to discuss the benefits of CT in the diagnosis of cryptorchid testes and describe an additional organ that may display CT "whirl sign."
Abdominal cocoon and adhesiolysis: a case report and a literature review
Authors: Hassan Al-Thani, Jamila El Mabrok, Noof Al Shaibani, Ayman El-Menyar
Journal: Case Rep Gastrointest Med (2013)

Abdominal cocoon is a rare cause of intestinal obstruction. It is difficult to diagnose in most of the cases preoperatively. Surgical removal of the membrane resulted in complete recovery in the majority of the cases. The exact etiology of abdominal cocoon is still unknown. We reported a male patient who presented with features of intestinal obstruction and has been diagnosed as abdominal cocoon intraoperatively.
Metastatic adenocarcinoma of the oesophagus to the submandibular gland-the imaging and pathological features of a rare phenomenon
Authors: Geoffrey Lie, Jonathan Chia, Jose Quiroga, David Howlett, Jane Topple
Journal: BJR Case Rep (2017)
MeSH terms: Case Reports

Metastatic disease affecting the submandibular gland is a rare entity, with just over a 100 cases documented. We present the case of a 55-year-old female with an apparently operable oesophageal primary adenocarcinoma, who was identified on staging PET scan and confirmed on ultrasound-guided biopsy to have metastatic disease in her left submandibular gland. The imaging and pathological findings are presented and compared with the current body of literature. Previously recognized primary sites of metastasis include the breast, thyroid, lung and genitourinary organs. We believe this to be the first documented case of oesophageal adenocarcinoma metastasising to the submandibular gland.
Testicular Vasculitis: A Sonographic and Pathologic Diagnosis
Authors: Anuj Dixit, Cameron Hague, Simon Bicknell
Journal: Case Rep Radiol (2017)
MeSH terms: Case Reports

Very little has been published about single-organ vasculitis of the testicle in the radiological literature. Consequently, it is a diagnosis that is unfamiliar to most radiologists. This case report describes the sonographic, pathologic, and laboratory findings of testicular vasculitis and reviews the available literature with regard to this subject.
The Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the Literature
Authors: Maxim Barnett, Farhan Ahmed, Radu Mihai, Asha Rattan, Malik Asif Humayun
Journal: Case Rep Endocrinol (2021)
MeSH terms: Case Reports

Hypercalcaemia and its systemic sequelae are a relatively common finding amongst patients in the field of endocrinology. Primary hyperparathyroidism, a frequent cause of hypercalcaemia, is often seen among middle-aged female patients, typically resulting from an underlying single-gland adenoma. Although patients may present with symptoms (nephrolithiasis, musculoskeletal discomfort, dehydration, or mood disturbance, to name a few), hypercalcaemia is rather frequently identified incidentally. In younger patients, a familial form of primary hyperparathyroidism must be considered, with a positive diagnosis mandating familial screening. Hyperparathyroidism-jaw tumour syndrome is one such autosomal dominant familial disorder, characterised by a mutation in the cell division cycle 73 (CDC73; also known as HRPT-2) tumour suppressor gene. This disorder is characterised by multiple pleiotropic phenomena, including recurrent primary hyperparathyroidism (and the effects of hypercalcaemia), neoplasms (such as uterine, renal, mandibular, and maxillary), and infertility. A patient not conforming to the classic candidacy for primary hyperparathyroidism requires consideration for a familial cause. Case Description. We present a rare diagnostic entity-hyperparathyroidism-jaw tumour (HPT-JT) syndrome-in a 36-year-old female with recurrent primary hyperparathyroidism, frequent nephrolithiasis, and infertility for 18 years prior to the diagnosis. We aim to promote awareness amongst medical professionals of this rare, but nonetheless essential differential diagnosis through a case report and review of the literature. Conclusion. Medical professionals must avoid diagnostic overshadowing and display a low threshold for genetic testing in younger patients with primary hyperparathyroidism. The importance of proper identification extends beyond the patient to their relatives and offspring.
A case report of misdiagnosed fetal lung mass and review of the literature
Authors: Zongyu Wang, Chang Xu, Taozhen He, Miao Yuan
Journal: Front Pediatr (2023)
Keywords: diagnosis, fetal lung interstitial tumor, fetal lung mass, pediatric lung tumor, surgery
MeSH terms: Case Reports

The patient was a male neonate, and a prenatal ultrasound had detected a right lung mass. He was born at term and after delivery had tachypnea and feeding difficulties. A chest x-ray and a computed tomography (CT) scan revealed a large mass in the right chest with compression on the right lung after birth. We initially considered congenital pulmonary airway malformation (CPAM). After conservative treatment, his respiratory symptoms worsened gradually, and he required continuous supplemental oxygen. The symptoms could not be relieved by puncturing due to a postnatal ultrasound having shown a mass with anechoic microcystic spaces. He therefore underwent an emergency thoracotomy and lobectomy at 14 days of age. The pathology was consistent with fetal lung interstitial tumor (FLIT). The patient remained healthy at the three-month follow-up. We reviewed the literature on FLIT and found that, to date, 23 cases have been reported worldwide.
The feasibility of delivering constraint-induced language therapy via the Internet
Authors: Rachelle Pitt, Deborah Theodoros, Anne J Hill, Amy D Rodriguez, Trevor Russell
Journal: Digit Health (2017)
Keywords: telerehabilitation, aphasia rehabilitation, constraint-induced language therapy

Objective:
This study is designed to determine the feasibility of the provision of an evidenced-based aphasia therapy, constraint-induced language therapy, via telerehabilitation. It describes the computer software that was developed specifically for the delivery of constraint-induced language therapy in the online environment and presents two case studies.
Methods:
Two participants with chronic aphasia were assessed before and after a two-week intensive treatment block of constraint-induced language therapy delivered via Web-based videoconferencing. The group-based, dual card request game utilized in face-to-face constraint-induced language therapy was transformed into an innovative and user-friendly Web-based game - Internet constraint-induced language therapy (iCILT). Participants accessed iCILT via the Internet from their own home every weekday for two weeks. Language and quality of life measures were administered pre- and post-therapy in order to detect treatment effects. Participant satisfaction information was also recorded.
Results:
Online delivery of iCILT was technically feasible and participant satisfaction was high with a number of benefits associated with telerehabilitation identified by participants. Post-treatment performance for language functioning and communication-related quality of life was variable for each participant, however improvements in naming were noted.
Conclusions:
Constraint-induced language therapy delivered via telerehabilitation may be a feasible alternative to traditional face-to-face therapy for people with chronic aphasia.
Laryngeal extra-skeletal Ewing sarcoma treated with DC-CTL immunotherapy: A case report and review of the literature
Authors: Hanrui Wang, Jianwei Wang, Qiang Wang, Yujuan Yang, Jing Guo, Chao Ren, Yakui Mou, Chuanliang Jia, Xicheng Song
Journal: Front Oncol (2022)
Keywords: extra-skeletal ewing sarcoma, immunotherapy, larynx, prognosis, surgery
MeSH terms: Case Reports

Extra-skeletal Ewing sarcoma (EES) is a rare sarcoma composed primarily of small round cells, capable of metastasizing and relapsing. Few cases of EES originating from the larynx have been reported, and no publications regarding laryngeal EES treated with dendritic cells-cytotoxic T lymphocytes (DC-CTL) immunotherapy have been found. We described a 29-year-old woman with a mass found in the larynx. Diffuse small round cells with scanty cytoplasm shown by histology test and extremely positive staining of CD99 revealed by immunohistochemistry helped determine the diagnosis of laryngeal EES. The patient survived for seven years with no signs of recurrence or metastasis after six cycles of DC-CTL immunotherapy based on traditional treatments. This case indicates that DC-CTL immunotherapy could be considered a new option for treating EES.
Management of Persistent Pruritus and Lichenoid Reaction Secondary to Nivolumab With Narrowband Ultraviolet B Phototherapy
Authors: Marie Donaldson, Joshua L Owen, Young K Chae, Jennifer N Choi
Journal: Front Oncol (2018)
Keywords: pd-1 inhibitor, dermatitis, immunotherapy, lichenoid, nivolumab, non-small cell lung cancer, phototherapy
MeSH terms: Case Reports

Immune checkpoint inhibitors targeting the programmed cell death receptor 1 (PD-1) are increasingly used to treat several malignancies, with the most common adverse event being cutaneous toxicity. We report the case of a 68-years-old man with stage IV non-small cell lung cancer treated with nivolumab who developed a pruritic, lichenoid eruption refractory to treatment with topical or systemic steroids, who was started on narrow band ultraviolet B therapy which resolved the reaction.