OpenMed/multicare-articles huggingface dataset:
A rare case of Listeria monocytogenes causing mycotic aneurysm of the common femoral artery: A case report
Authors: T Pathmarajah, S Chu, K Sieunarine
Journal: Int J Surg Case Rep (2019)
Keywords: case report, femoral, graft infection, listeria, mycotic aneurysm

Introduction:
Mycotic aneurysms are an uncommon occurrence, withStaphylococcus and Salmonella species found to be the causative pathogen in up to 95% of cases. We believe this is the first described case of a common femoral artery mycotic aneurysm due to Listeria monocytogenes.
Presentation of case:
A 66-year-old male presented with a two-month history of an increasing painful mass in his left groin, on the background of immunosuppression treatment for ankylosing spondylitis. He was afebrile on assessment, with a normal white cell count. Contrast enhanced CT scan showed a common femoral artery aneurysm, with no infective features. His aneurysm was excised and repaired with a Dacron tube graft. L. monocytogenes was cultured from the aneurysm tissue, and he was commenced on appropriate antibiotic treatment. The prosthetic graft was also replaced with a venous bypass of the aneurysm.
Discussion:
L. monocytogenes is a rare cause of mycotic aneurysm with less than 40 cases reported in the literature. Immunosuppression is a recognised risk factor for Listerial infections. Immunocompromised patients may not display typical clinical or biochemical features associated with a mycotic aneurysm. Prosthetic graft infections are associated with significant mortality, with excision of the prosthetic material and venous reconstruction associated with good outcomes for eradicating infection.
Conclusion:
This report highlights the importance of obtaining intraoperative tissue samples for microbiological and histopathological assessment in immunocompromised patients. This is important for the detection of rare organisms such as L.monocytogenes, requiring targeted antibiotic therapy. Inappropriate treatment of Listerial infections can result in serious invasive illness.
Refractory thrombocytopenia responds to octreotide treatment in a case of evans syndrome with gastric neuroendocrine tumor
Authors: Kocfa Chung-Delgado, Alejandro Revilla-Montag, Sonia Guillén-Bravo, Hugo Ríos-Díaz, José C Alva-Muñoz
Journal: Case Rep Hematol (2013)

A 37-year-old woman with history of Evans Syndrome with poor response to high-dose corticoid treatment presented to the emergency department with gastrointestinal and vaginal bleeding. The patient was later diagnosed with severe thrombocytopenia and a stage G1, well-differentiated gastric neuroendocrine tumor, confirmed by a biopsy. A total gastrectomy was performed to eradicate the tumor. After being treated with a total splenectomy for her Evans Syndrome with no clinical or laboratory improvement, she began regular treatment with octreotide on the basis of a possible hepatic metastasis. Days after the initiation of the octreotide, an increase in the platelet count was evidenced by laboratory findings, from 2,000 platelets/mm(3) to 109,000 platelets/mm(3). Weeks later, the hepatic metastasis is discarded by a negative octreotide-body scan, and the octreotide treatment was interrupted. Immediately after the drug interruption, a progressive and evident descent in the platelet count was evidenced (4000 platelets/mm(3)). The present case report highlights the possible association between octreotide treatment and a severe thrombocytopenia resistant to conventional treatment.
Tuberculous osteomyelitis of the hyoid bone: a case report
Authors: Paul Emerson, Ajay Philip, George M Varghese, Regi Thomas
Journal: Case Rep Otolaryngol (2013)

Skeletal tuberculosis is a well-known disease entity. We report the first case involving hyoid bone and the use of polymerase chain reaction-based test in detection and management. A 62-year-old male presented with neck swelling of a 20-day duration along with change of voice and dysphagia. Examination revealed a cystic, osteolytic lesion of the hyoid bone which histopathologically demonstrated features of granulomatous infection. A polymerase chain reaction test confirmed the diagnosis of tuberculosis.
Computed Tomography Scan and ICD Interaction
Authors: Jose M Porres, Jose L Cerezuela, Oscar Luque, Pilar Marco
Journal: Case Rep Med (2009)
MeSH terms: Case Reports

Although it has been considered a safe procedure, computed tomography scanning uses high doses of radiation and can cause malfunctioning in those patients with ICD when the radiation is directly incident on the device. We present a case of ventricular oversensing during a thoracic computed tomography.
Leprosy with Atypical Skin Lesions Masquerading as Relapsing Polychondritis
Authors: Punit Pruthi, Hariharan Munganda, Amit Bangia, Uma Rani, Rajesh Budhiraja, Swapnil Brajpuriya
Journal: Case Rep Infect Dis (2016)
MeSH terms: Case Reports

Leprosy can present with a variety of clinical manifestations depending on the immune status of the individual. After dermatological and neurological involvement, rheumatic features specially various forms of arthritis are the third most common manifestation of the disease. We describe a unique case of a 22-year-old patient presenting with external ear involvement mimicking relapsing polychondritis along with inflammatory joint symptoms and skin lesions. Ear involvement in relapsing polychondritis characteristically is painful and spares the noncartilaginous ear lobules, in contrast to painless ear involvement in leprosy affecting the lobules as well. Histopathology confirmed the diagnosis, although the ear and skin lesions were not classical of leprosy. Such a presentation of leprosy closely mimicking relapsing polychondritis has not been described previously. Tissue diagnosis should always be attempted whenever possible in patients presenting with autoimmune features, so that inappropriate therapy with immunosuppressants is avoided.
Rare Associations with Posterior Urethral Valves
Authors: Ahmed Osama Mohamed, Bala Eradi, Anthony Owen, Ashok Rajimwale
Journal: Case Rep Urol (2021)
MeSH terms: Case Reports

Posterior urethral valves are a common cause of congenital bladder outlet obstruction. Known associations include cardiac malformations and gastrointestinal abnormalities. In this case series, we report on two cases of PUV associated with anorectal malformations along with a case of PUV in monochorionic diamniotic twins. We explore the difficulty in achieving a diagnosis and the final management. The association of posterior urethral valves in a patient with anorectal malformation should be suspected in case of associated oligohydramnios or oliguria postnatally. There should be a high index of suspicion in twin pregnancy even if only one of the twins is suspected of bladder outlet obstruction.
Ulcerative Colitis of the Neovagina in a Toddler with Cloaca and Chronic Kidney Disease
Authors: Marta Erculiani, Cinzia Zanatta, Enrico Vidal, Stefano Martelossi, Paola Midrio
Journal: European J Pediatr Surg Rep (2021)
Keywords: anorectal malformation, cloaca, colitis, diagnosis, neovagina, ulcerative
MeSH terms: Case Reports

The case of a toddler with long-channel cloaca, mild chronic kidney disease (CKD) due to renal dysplasia, and early onset of ulcerative colitis (UC) is herein reported. The patient underwent definitive repair of cloaca, that included vaginal elongation with colon, at 5 months of age and was admitted for episodes of vaginal bleeding at 22 months of age. A vaginoscopy revealed a severe inflammation of the colonic neovagina. As rectal bleeding was also noticed, she underwent a colonscopy that showed the same macroscopic inflammatory picture. Neovaginal and colonic biopsies confirmed UC. The mother turned out to be affected by UC since adolescence. The patient is now on oral therapy with mesalazine and topical steroid and mesalazine in the neovagina. The association between cloaca and inflammatory bowel disease (IBD) is anecdotal, but the family history of IBD should be considered when planning the surgical reconstruction of patients with cloaca. In this patient, the occurrence of UC may require a new neovagina in the future and the concomitance of CKD may complicate the overall management due to the potential nephrotoxicity of drugs used for UC therapy.
Treating Supraventricular Tachycardia With Amiodarone in a Patient With Ebstein's Anomaly
Authors: Mohammed Y Alnami, Hassan M Hassan Almalki, Nadher M Hassan Hakami, Omar E Masmali
Journal: Cureus (2023)
Keywords: amiodarone, anomaly, arrhythmia, ebstein, ebstein's anomaly, supraventricular tachycardia
MeSH terms: Case Reports

Ebstein's anomaly is a congenital deformity marked by disease of the tricuspid valve and right cardiac hypertrophy. The severity, morphology, and appearance of Ebstein's anomaly cases might vary greatly. We discuss a case of an eight-year-old child with Ebstein's anomaly who presented with supraventricular tachycardia and was effectively treated with amiodarone after initial treatment with adenosine failed to reduce the heart rate.
Hypokalemic Paralysis due to Primary Sjögren Syndrome: Case Report and Review of the Literature
Authors: A Garza-Alpirez, A C Arana-Guajardo, J A Esquivel-Valerio, M A Villarreal-Alarcón, D A Galarza-Delgado
Journal: Case Rep Rheumatol (2017)
MeSH terms: Case Reports

Tubulointerstitial nephritis (TIN) is the main renal involvement associated with primary Sjögren syndrome (pSS). TIN can manifest as distal renal tubular acidosis (RTA), nephrogenic diabetes insipidus, proximal tubular dysfunction, and others. We present a 31-year-old female with hypokalemic paralysis due to distal RTA (dRTA). She received symptomatic treatment and hydroxychloroquine with a good response. There is insufficient information on whether to perform a kidney biopsy in these patients or not. The evidence suggests that there is an inflammatory background and therefore a potential serious affection to these patients, such as hypokalemic paralysis. We found 52 cases of hypokalemic paralysis due to dRTA in pSS patients. The majority of those patients were treated only with symptomatic medication. Patients who received corticosteroids had stable evolution even though they did not have another symptomatology. With such heterogeneous information, prospective studies are needed to assess the value of adding corticosteroids as a standardized treatment of this manifestation.
Extensive Causative Esophagitis Caused by Thermal Injury: A Case Report and Review of the Literature
Authors: Cherng Harng Lim, Hsu-Heng Yen, Wei-Wen Su, Cherng-Jyr Lim, Hao-Chien Tsai, Shi-Ting Chen
Journal: Case Rep Gastrointest Med (2017)
MeSH terms: Case Reports

Esophagus thermal injury is a rare case that can be easily overlooked by practitioners. We herein present a case of thermally induced diffuse corrosive esophagitis with complaints of dysphagia and retrosternal chest pain after having steamed pork. A thorough disease course was demonstrated by serials of endoscopy images and video. A comprehensive review of articles and a concise overview of esophageal thermal injury clinical manifestation, disease process, typical endoscopy features, pharmacomanagement option, and outcomes will be conducted in this article.
Successful treatment of dupilumab in Kimura disease independent of IgE: A case report with literature review
Authors: Boyun Yang, Hanxiao Yu, Minyue Jia, Wo Yao, Ran Diao, Bohui Li, Yongfang Wang, Ting Li, Liuya Ge, Huiying Wang
Journal: Front Immunol (2022)
Keywords: kimura disease, anti-il-4/il-13, anti-ige, biologics, dupilimab, treatment
MeSH terms: Biological Products / therapeutic use, Kimura Disease / drug therapy, Review, Case Reports, Research Support, Non-U.S. Gov't, Antibodies, Monoclonal, Humanized / therapeutic use, Humans, Immunosuppressive Agents, Male, Middle Aged, Omalizumab / therapeutic use, dupilumab, Antibodies, Monoclonal, Humanized, Omalizumab, Immunosuppressive Agents, Biological Products

Kimura disease (KD) is a rare and benign chronic inflammatory disease of unknown cause. It is characterized by subcutaneous granuloma of soft tissues in the head and neck region, increased eosinophil count, and elevated serum IgE. Currently, no definitive treatments are recommended. A 57-year-old Chinese man was diagnosed with KD after 7 years of slow subcutaneous masses growth. The patient underwent treatment of oral glucocorticoids for 1 year, but the masses recurred as the dosage was tapered down. Subsequent anti-IgE therapy of omalizumab administered subcutaneously at 450 mg/day at a 4-week interval did not show improvement. The size of masses and serum IgE and circulating eosinophils did not decrease significantly after 19 cycles of continuous treatment. Ultimately, switched strategy of dupilumab was applied at an initial dose of 600 mg, followed by 300 mg every 2 weeks for 4 months. This treatment demonstrated dramatical effects with reduced masses in each area and fast dropdown of eosinophil counts, while the high level of serum IgE remained without changes. Recently, different biologics including anti-IgE, anti-IL-5, and anti-IL-4/IL-13 have been applied to treat KD with satisfied results and help to explore the pathogenesis of this rare disease. To our knowledge, this is the first report that demonstrates the effects of two different biologics in the same patient and reveals the impressive clinical efficacy of dupilumab to treat KD independent of IgE. Therefore, further investigation of the underlying mechanism and the development of diagnosis and treatment of KD is valuable.
Nonsurgical management of an extensive perforative internal root resorption with calcium-enriched mixture cement
Authors: Ehsan Esnaashari, Arezou Pezeshkfar, Mahta Fazlyab
Journal: Iran Endod J (2015)
Keywords: cbct, cem cement, calcium-enriched mixture cement, cone-beam computed tomography, internal root resorption, root resorption
MeSH terms: Case Reports

Internal inflammatory root resorption (IIRR) is a rare condition of the root canal and if it is left untreated it may lead to destruction of the surrounding dental hard tissues. Odontoclasts are responsible for this situation which can potentially perforate the root. Many initiating factors have been mentioned for IIRR, almost all causing chronic inflammation in the vital pulp. IIRR is usually symptom free, but in cases of root perforation, a sinus tract usually forms. The prognosis of treatment depends on the size of lesion with small lesions being managed with good prognosis. However, in case of notable destruction of the tooth, the prognosis is poor and tooth extraction may become inevitable. This report represents the management of an extensive perforative IIRR that was successfully sealed with calcium-enriched mixture (CEM) cement. After 12 months the tooth was still symptomless and in function.
A Case of Atopic Myelitis with Cervical Cavernous Angioma
Authors: Miyuki Fukuda, Hiroaki Manabe, Nobuhiro Sasaki, Masayuki Kuroda, Minoru Hoshimaru, Shigeo Ueda
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

Atopic myelitis, a type of myelitis which appears in patients with elevated serum levels of immunoglobulin E (IgE), occurs more commonly in the cervical spinal cord, but this mechanism has not yet been elucidated. Herein, we experienced a case of atopic myelitis developed during the growth of cervical cavernous angioma caused by bleeding. A 37-year-old woman suffered from hand swelling caused by a house cat licking. At the same time when cavernous angioma had grown, she experienced a numbness in her four extremities, and multifocal peritumoral hyperintense spinal cord signals were seen. The diagnosis of atopic myelitis was made because we observed significantly elevated levels of specific IgE antibody to cat dander. Symptoms disappeared immediately after steroid pulse therapy. We subsequently resected a cavernous angioma, and eosinophil invasion was found inside it. This is the first case report of atopic myelitis which developed in association with spinal cord vascular lesions. A local blood-brain barrier breakdown due to hemorrhagic lesions of the spinal cord may have contributed to the onset of atopic myelitis.
Intravascular Fasciitis of the Jugular Vein Mimicking Thrombosis and Sarcoma: A Case Report
Authors: Guo Xin Chen, Chu Wen Chen, Xiao Rong Wen, Bin Huang
Journal: Front Surg (2021)
Keywords: internal jugular vein, intravascular fasciitis, sarcoma, surgery, thrombosis
MeSH terms: Case Reports

Background: Intravascular fasciitis is a rare disease that is a reactive proliferative lesion of myofibroblasts. There are rare reports that intravascular fasciitis has invaded the jugular vein as seen in this case. Case Presentation: A 41-year-old female presented with right neck dull pain for 20 days. The appearance of the subcutaneous mass was oval, pink hyaline, well-demarcated, and measuring ~5 mm in diameter. Microscopically, the mass was composed of spindle cells arranged in intersecting fascicles. Immunohistochemical stains showed that the spindle cells were positive for smooth muscle actin and negative for S-100, Desmin, MyoD1, and elastin stains. The nuclei of the spindle cells were relatively uniform, and mitotic activity was observed. The overall morphological and immunohistochemical features are consistent with intravascular fasciitis. Conclusion: Due to the rapid growth and vascular invasion, intravascular fasciitis created a high risk of misdiagnosing it as a sarcoma or thrombosis. Reporting this uncommon case, we raise awareness of this non-neoplastic lesion, and careful, light microscopic examination combined with immunohistochemical staining aids in the diagnosis of intravascular fasciitis.
Serum Cytokine Profile in a Patient Diagnosed with Dysferlinopathy
Authors: Svetlana F Khaiboullina, Ekaterina V Martynova, Sergey N Bardakov, Mikhail O Mavlikeev, Ivan A Yakovlev, Arthur A Isaev, Roman V Deev, Albert A Rizvanov
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

Limb-girdle muscular dystrophy type 2 (LGMD2B) is a mild form of dysferlinopathy, characterized by limb weakness and wasting. It is an autosomal recessive disease, with currently 140 mutations in the LGMD2B gene identified. Lack of functional dysferlin inhibits muscle fiber regeneration in voluntary muscles, the main pathological finding in LGMD2B patients. However, the immune system has been suggested to contribute to muscle cell death and tissue regeneration. Serum levels of 27 cytokines were evaluated in a dysferlinopathy patient. Levels of 8 cytokines differed in patient serum compared to controls. Five cytokines (IL-10, IL-17, CCL2, CXCL10, and G-CSF) were higher while 3 were lower in the patient than in controls (IL-2, IL-8, and CCL11). Together, these data on serum cytokine profile of this dysferlinopathy patient suggest immune response activation, which could explain leukocyte infiltration in the muscle tissue.
Case Report: A Giant Left-Ventricular Intramural Pseudoaneurysm Arise From Ruptured Left Sinus of Valsalva Aneurysm
Authors: Minghui Hua, Yufan Gao, Jianhui Li, Fang Tong, Ximing Li, Hong Zhang
Journal: Front Cardiovasc Med (2021)
Keywords: cardiac magnetic resonance, computed tomography, echocardiogram, sinus of valsalva aneurysm, ventricular intramural pseudoaneurysm
MeSH terms: Case Reports

In this report, we present a case study of an extremely rare left sinus Valsalva aneurysm (SVA) rupture into the left-ventricular myocardium. Acute ozone inhalation and long-term hypertension are possible contributors to the condition. Utilizing multimodal cardiovascular imaging techniques [echocardiogram, computed tomography (CT), and cardiac magnetic resonance (CMR)], a large, left-ventricular, intramural pseudoaneurysm (IPA) arising from the ruptured left SVA, was clearly observed anatomically and functionally. Subsequently, our patient underwent patch repair and valvoplasty which offered an excellent prognosis. This report describes the manifestation of the ruptured left SVA and its possible etiology. This case also emphasizes the need for multimodal imaging for subsequent surgical repair.
Elusive Enterobacter cloacae causing pacemaker endocarditis
Authors: Naji Maaliki, Jorge Verdecia, Malleswari Ravi
Journal: IDCases (2021)
Keywords: cardiac implantable electronic device endocarditis, endocarditis, enterobacter cloacae, non-hacek gram-negative rods, pacemaker endocarditis
MeSH terms: Case Reports

An 80-year-old patient was admitted for fever, chills, and chest wall pain. He had a past medical history significant for heart failure with a cardiac resynchronization therapy pacemaker implantation. Extensive workup revealed Enterobacter cloacae endocarditis of the pacemaker leads and the mitral valve, a rare etiology with an unidentified source in our patient. He was managed with a rather unconventional method which proved to be successful. This case sheds light on non-HACEK (other than Haemophilus spp., Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, or Kingella spp). gram-negative organisms, and particularly E. cloacae, as uncommon causes of endocarditis with elevated mortality, and discusses potential treatment modalities.
Case report: Heart Mate III for systemic right ventricular support in a patient with hypoplastic left heart syndrome
Authors: Maja Hanuna, Jelena Pabst von Ohain, Nikolaus Haas, Christoph S Mueller, Robert Dalla-Pozza, Marcus Fischer, Frank Born, Christine Kamla, Andre Jakob, Christian Hagl, Jürgen Hörer, Sebastian G Michel
Journal: Front Cardiovasc Med (2023)
Keywords: vad—ventricular assist device, case report, failing fontan, hypoplastic left heart syndrome, mechanical circulatory support, right ventricular (rv) failure
MeSH terms: Case Reports

Ventricular assist device implantation presents a possible bridge to heart transplantation for patients with failing Fontan physiology. However, evidence regarding outcome and possible pitfalls associated with the Fontan circulation is still insufficient. We describe the course of a 13-year-old male, who was born with hypoplastic left heart syndrome and underwent HeartMate III implantation due to refractory failure of the systemic right ventricle.
Unusual presentation of meningococcal meningitis in the elderly and utility of CSF PCR testing
Authors: Elizabeth Ranson, Hannah Ship, Omai Garner, Shangxin Yang, Debika Bhattacharya
Journal: Access Microbiol (2020)
Keywords: pcr test, elderly meningitis, meningococcal meningitis, multiplex pcr
MeSH terms: Case Reports

We present an unusual case of a previously healthy 74-year-old man who presented with diffuse weakness, severe myalgias, petechial palmar rash and hypotension, but without fever, altered mental status, nuchal rigidity or headache, who was ultimately found through PCR testing to have meningococcal meningitis.
Primary carcinoid tumor of the ileal efferent limb of an ileovesicostomy: a case report
Authors: Adamantios M Mellis, Daniel C Parker, David D Buethe, Gennady Slobodov
Journal: Case Rep Urol (2011)
MeSH terms: Case Reports

We report on the evaluation and management of a 47-year-old white male found to have primary carcinoid tumor of the ileal segment of his diverting ileovesicostomy thirty-five months after initial creation. Subsequent to presentation with intermittent gross hematuria, CT urogram highlights an 8 mm enhancing lesion near the enterovesical junction of urinary diversion. Office cystoscopy confirms presence of a lesion that was later endoscopically resected and found to be a well-differentiated carcinoid tumor. Evaluation with serum markers, direct visualization utilizing endoscopy, and imaging was without finding of alternate primary or metastatic lesions. The patient ultimately had the proximal ileal portion of his ileovesicostomy excised and the distal portion converted into an ileal conduit. After briefly discussing the carcinoid tumor and the carcinoid syndrome it may cause, we review the literature on the incidence of carcinoid tumors in a population requiring the use of intestine in the urinary tract.