OpenMed/multicare-articles huggingface dataset:
The Patient-Specific Implant Created with 3D Printing Technology in Treatment of the Irreparable Radial Head in Chronic Persistent Elbow Instability
Authors: Suriya Luenam, Arkaphat Kosiyatrakul, Chanon Hansudewechakul, Kantapat Phakdeewisetkul, Boonrat Lohwongwatana, Chedtha Puncreobutr
Journal: Case Rep Orthop (2018)
MeSH terms: Case Reports

Successful treatment of the chronic persistent elbow instability is a challenge for orthopedic surgeons. In this form, it is important to recognize and restore the osseous stabilizer in order to obtain the concentric reduction. In the present report, we describe a case of such injury with irreparable radial head treated with patient-specific radial head prosthesis which was created with 3D printing technology. To our knowledge, this is the first report in clinical use of this kind of prosthesis for the radial head fracture. At a 24-month follow-up visit, the patient was satisfied with the functional outcomes. The Mayo Elbow Performance Index (MEPI) increased from 20 points at the preoperative day to 85 points, and the patient-based Disabilities of the Arm, Shoulder, and Hand (DASH) was reduced from 88.33 points to 28.33 points. Due to the favorable result, replacement of the radial head with the patient-specific implant could be a useful treatment for the irreparable radial head in chronic persistent elbow instability.
Systemic granulomatous diseases associated with multiple palpable masses that may involve the breast: case presentation and an approach to the differential diagnosis
Authors: Rodrigo Menezes Jales, Patrick Nunes Pereira, Rafael Fantelli Stelini, Luciano Moro
Journal: Case Rep Med (2014)

Palpable mass is a common complaint presented to the breast surgeon. It is very uncommon for patients to report breast mass associated with palpable masses in other superficial structures. When these masses are related to systemic granulomatous diseases, the diagnosis and initiation of specific therapy can be challenging. The purpose of this paper is to report a case initially assessed by the breast surgeon and ultimately diagnosed as granulomatous variant of T-cell lymphoma, and discuss the main systemic granulomatous diseases associated with palpable masses involving the breast.
Chiropractic management of post spinal cord stimulator spine pain: a case report
Authors: Rachel M Perrucci, Christopher M Coulis
Journal: Chiropr Man Therap (2017)
Keywords: chiropractic, failed back surgery syndrome, post-surgical spine pain, spinal cord stimulator

Background:
A brief overview of failed back surgery syndrome, with emphasis on low back pain status post spinal cord stimulation, and post-surgical spinal manipulation is presented.
Case presentation:
Four cases of patients within the VA Connecticut Health Care System presenting between July 2014 and July 2015 reporting low back pain after surgical insertion of spinal cord stimulators are discussed. This study describes the outcomes experienced by four patients with low back pain status post implanted spinal cord stimulators receiving manual therapy in the form of lumbar spine manipulation or mobilization.
Conclusion:
All four patients denied adverse effects to spinal manipulation/mobilization and onset of new symptoms after treatment; two patients reported durable reduction in low back pain with increased tolerance to walking, standing, or lying down, one reported temporary relief of low back pain, and one reported no change in symptoms. Further investigation is needed to determine the benefit of spinal manipulation in patients with implanted spinal cord stimulators, but this study has shown the absence of adverse effects from manipulation or mobilization treatment, in regards to SCS.
Non-diabetic metabolic nodular glomerulosclerosis
Authors: Catarina Mateus, Eunice Cacheira, Ivo Laranjinha, Jorge Dickson, Augusta Gaspar
Journal: Clin Nephrol Case Stud (2022)
Keywords: idiopathic nodular glomerulosclerosis, nodular glomerulosclerosis
MeSH terms: Case Reports

Nodular glomerulosclerosis is classically associated with diabetes. Nowadays, it is well known that this histologic pattern can be the presentation of different diseases, including dysproteinemias and amyloidosis. Most recently, the previously thought to be idiopathic nodular glomerulosclerosis has been associated with hypertension, smoking, and obesity. We present a clinical case of a non-diabetic 74-year-old man, with hypertension and heavy smoking history, who presented with nephrotic proteinuria and chronic kidney disease. We review the literature and propose a different nomenclature for this pattern of metabolic glomerulopathy.
The renal hydatid cyst: report on 4 cases
Authors: Mohamed Rami, Khalid Khattala, Aziz ElMadi, My Abderrahmane Afifi, Youssef Bouabddallah
Journal: Pan Afr Med J (2011)
Keywords: hydatid cyst, morocco, child, kidney
MeSH terms: Echinococcosis / therapy, Echinococcosis, Hepatic / therapy, Kidney Diseases / parasitology, Case Reports, Antiparasitic Agents / therapeutic use, Child, Combined Modality Therapy, Echinococcosis / diagnosis, Echinococcosis, Hepatic / diagnosis, Female, Follow-Up Studies, Humans, Kidney Diseases / diagnosis, Kidney Diseases / therapy, Laparoscopy / methods, Male, Morocco, Treatment Outcome, Antiparasitic Agents

The hydatid cyst is a frequent pathology in Morocco. All localizations are possible. However, renal hydatid cyst is still rare; it constitutes about 2.5% of all localizations. We report 4 cases admitted at the Department of Pediatric Surgery of the University Hospital of Fes in the period running from February 2004 to January 2008. The four patients were of ages ranging from 8 to 11 years old. Two of them had double localization in the kidney and liver. The imaging was the diagnostic tool of choice. The patients benefited from surgical treatment; two were treated using standard surgery while laparoscopic surgery was used in the next two. Anti-parasitic medication was associated in the post-surgery stage for a period of six months. The evolution was good for all the patients.
An Unusual Traumatic Presentation: Luxatio Erecta Humeri and Concomitant Hip Dislocation
Authors: Mehmet Demirel, Berkan Anarat, Mehmet Ersin, Ali Erşen, Cengiz Şen
Journal: Case Rep Orthop (2016)
MeSH terms: Case Reports

Introduction. Inferior dislocation of the glenohumeral joint, known as luxatio erecta humeri, and posterior hip dislocation are both rare presentations in the emergency department. The most common aetiology is falling for luxatio erecta humeri. The aim of this manuscript was to present a unique case in terms of luxatio erecta humeri, which has a different aetiology, treatment method, and concomitant injury. Presentation of Case. We report a construction worker who was rescued from a collapsed building who presented with both luxatio erecta humeri and complex posterior hip dislocation. An orthopaedic surgeon reducted luxatio erecta humeri with a one-step reduction technique under procedural anaesthesia as soon as the patient's vital signs were stable. Discussion. Different concomitant injuries and various injury mechanisms have been described in regard to inferior shoulder dislocation in the literature. However, posterior dislocation of the hip as a concomitant distant region injury and trapping as an injury mechanism for luxatio erecta humeri are being described for the first time in this case report. Two reduction manoeuvers, one-step and two-step, have been used for this dislocation. Some authors suggested that a two-step manoeuver can be more easy to apply. In our specific case, luxatio erecta was easily reducted by a single operator in a single attempt. Conclusion. Luxatio erecta humeri may occur from trapping and complex injuries can accompany luxatio erecta humeri in patients with multiple trauma. A one-step closed reduction can be easily applied by a single operator under procedural anaesthesia.
Fairness and efficiency considerations in COVID-19 vaccine allocation strategies: A case study comparing front-line workers and 65-74 year olds in the United States
Authors: Eva Rumpler, Justin M Feldman, Mary T Bassett, Marc Lipsitch
Journal: PLOS Glob Public Health (2023)

The COVID-19 epidemic in the United States has been characterized by two stark disparities. COVID-19 burden has been unequally distributed among racial and ethnic groups and at the same time the mortality rates have been sharply higher among older age groups. These disparities have led some to suggest that inequalities could be reduced by vaccinating front-line workers before vaccinating older individuals, as older individuals in the US are disproportionately Non-Hispanic White. We compare the performance of two distribution policies, one allocating vaccines to front-line workers and another to older individuals aged 65-74-year-old. We estimate both the number of lives saved and the number of years of life saved under each of the policies, overall and in every race/ethnicity groups, in the United States and every state. We show that prioritizing COVID-19 vaccines for 65-74-year-olds saves both more lives and more years of life than allocating vaccines front-line workers in each racial/ethnic group, in the United States as a whole and in nearly every state. When evaluating fairness of vaccine allocation policies, the overall benefit to impact of each population subgroup should be considered, not only the proportion of doses that is distributed to each subgroup. Further work can identify prioritization schemes that perform better on multiple equity metrics.
Fingertips ischemia, nephroangiosclerosis, and focal segmental glomerulosclerosis: is genetic thrombophilia the unique explanation?
Authors: Lisa Giovannini, Carlo Donadio
Journal: Case Rep Med (2014)

Case Presentation. 53-years-old-man with essential hypertension and nonnephrotic proteinuria (1.3 gr/24 h) and with normal renal function (eGFR-MDRD 123 mL/min/1.73 m(2)) was admitted to nephrology department; kidney biopsy showed FSGS; two years later the patient presented with ulceration and ischemic gangrene of the IV and V right-hand fingertips; genetic analysis demonstrated polymorphism of the methylenetetrahydrofolate reductase genes C677T (heterozygote C677T/1298AC with normal value of homocysteine) and mutations of prothrombin gene G20210A and of plasminogen activator inhibitor-1 4G/5G 675 with slight increase of its value. After five years from biopsy, 24-hours proteinuria was still around 1-1.3 g/die; renal function was still normal (eGFR 107 ml/min/1.73 m(2)). These data are against the previous diagnosis of primary FSGS. We hypothesize that genetic thrombophilia may explain all the clinical signs of our patient. Conclusions. Alterations in genes of thrombophilia should be ruled out in patients with bioptic diagnosis of "primary" FSGS, in particular if clinically atypical.
A Rare Complication During Transcatheter Closure of Double Atrial Septal Defects With Incomplete Cor Triatriatum Dexter: A Case Report
Authors: Ping-Hong Chen, Yi-Ching Liu, Zen-Kong Dai, I-Chen Chen, Shih-Hsing Lo, Jiunn-Ren Wu, Yen-Hsien Wu, Jong-Hau Hsu
Journal: Front Cardiovasc Med (2022)
Keywords: atrial septal defect, complication, cor triatiatum dexter, heart ischemia, percutaneous catheterization
MeSH terms: Case Reports

The cor triatiatum dexter is an embryologic remnant derived from the right atrium and totally separate from the right atrium. An incomplete cor triatiatum dexter (iCTD) means a partially obstructive remnant at the right atrium. It is usually formed by a remnant of the Eustachian valve (EV), Thebesian valve (ThV), or Chiari network (CN). This anatomic variant is usually asymptomatic but is often associated with other heart abnormalities including atrial septal defects (ASDs), and has the potential to hamper percutaneous heart procedures such as electrophysiological study or ASD closure. Herein, we report a rare complication, transient heart ischemia, in transcatheter closure of double ASDs in a 55-year-old woman with EV. This rare complication was thought to be caused by coronary sinus obstruction during device placement. The ischemic change was resolved spontaneously after we withdrew the device. For a second attempt, we adjusted the position of the device to avoid coronary sinus obstruction under transesophageal echocardiogram guidance and the device was smoothly deployed in a good position with a minimal residual shunt. This case suggests that anatomy details in percutaneous heart procedures are important, and this rare and dangerous complication, heart ischemia, should be identified immediately during the procedure.
Interstitial de novo 18q22.3q23 deletion: clinical, neuroradiological and molecular characterization of a new case and review of the literature
Authors: Elisa Tassano, Mariasavina Severino, Silvia Rosina, Riccardo Papa, Domenico Tortora, Giorgio Gimelli, Cristina Cuoco, Paolo Picco
Journal: Mol Cytogenet (2016)
Keywords: 18q- syndrome, array cgh, brain mri, diffusion tensor imaging, radial diffusivity, spectroscopy
MeSH terms: Case Reports

Background:
Deletions of the long arm of chromosome 18 cause a common autosomal syndrome clinically characterized by a protean clinical phenotype.
Case presentation:
We report on a 16-month-old male infant affected by fever attacks apparently unrelated with any infectious or inflammatory symptoms, growth retardation, bilateral vertical talus, congenital aural atresia, dysmorphisms, mild psychomotor delay, and peculiar neuroradiological features. Array-CGH analysis revealed one of the smallest 18q22.3q23 interstitial deletions involving five genes: TSHZ1, ZNF516, ZNF236, MBP, and GALR1.
Conclusions:
Herein we focus on previously unreported heralding symptoms and neuroradiological abnormalities which enlarge the spectrum of 18q deletion syndrome demonstrating that a small deletion can determine a complex phenotype.
A Band That Causes Leaky Valves: Severe Mitral Regurgitation due to Left Atrial Fibrous Band-A Case Report and Literature Review
Authors: Christopher Nnaoma, Gurdarshan Sandhu, Christoph Sossou, Ilan Vavilin, Jose Bustillo, Anshu Garg
Journal: Case Rep Cardiol (2019)
MeSH terms: Case Reports

Left atrial fibrous band is a rare clinical and echocardiographic finding characterized by the presence of a fibrous band attached to the mitral valve. Diagnosis is accomplished with transesophageal echocardiography (TEE), live 3D imaging, or cardiac MRI. Most patients are asymptomatic and incidental findings. However, in rare cases, an atrial fibrous band can produce symptoms such as dyspnea on exertion, fatigue, and lightheadedness secondary to mitral regurgitation (MR) which can lead to heart failure if unattended to. More serious complications such as cardioembolic phenomenon can occur. We herein report a case of a 55-year-old male with hypertension who presented with dyspnea on exertion and chest pain. Transthoracic echocardiography (TTE) showed mitral valve prolapse with moderate to severe mitral regurgitation. TEE showed an atrial fibrous band. Given the patient's poor exercise tolerance, he was taken to surgery for a mitral annuloplasty.
Epitheliod leiomyoma of the bladder: an unusual case of irritative and obstructive voiding symptoms
Authors: Ali Kaviani, Abdollah Razi, Hooman Mokhtarpour, Mohammad Mohsen Mazloomfard, Aida Moeini, Hooman Bahrami-Motlagh
Journal: Case Rep Urol (2012)
MeSH terms: Case Reports

Epitheloid leiomyoma is a very rare subtype of benign mesothelial tumors of the bladder. A 46-year-old female patient presented to our hospital with prolonged dysuria, frequency, and recurrent urinary tract infections. Bimanual examination revealed a mobile, round mass in bladder. There was a round hyperdense intravesical mass near bladder neck in computed tomography (CT) scan that was compatible with her magnetic resonance imaging (MRI). A well defined 3 × 4 centimeter mass was seen in superolateral part of bladder neck during cystoscopy. The patient underwent partial cystectomy and histopathologic findings confirmed the diagnosis of epithelioid leiomyoma. The patient's followup was uneventful in a period of 2 years. Size and anatomic location of this tumor were major factors that affect on treatment.
Minimally Invasive Robotic-Assisted Cystolithotomy in a Complicated Urinary Diversion: A Feasible and Safe Approach
Authors: A Haffar, C Crigger, T Trump, M Jessop, M W Salkini
Journal: Case Rep Urol (2021)
MeSH terms: Case Reports

Urinary diversion following radical cystectomy and neoadjuvant chemotherapy is the gold standard for the management of muscle-invasive bladder cancer. Urinary diversions are at an increased risk of urolithiasis as a result of various factors. Traditional surgical intervention has included open cystolithotomy which has given way to minimally invasive techniques as of late. We describe a case of a robotic-assisted cystolithotomy from a neobladder in a 54-year-old female patient with muscle-invasive bladder cancer. This is the first description of a robotic-assisted removal of a stone in an orthotopic neobladder. This approach has many advantages, especially in the removal of larger stones. Further study is needed to investigate the efficacy and success of this approach.
De novo post-transplant thrombotic microangiopathy localized only to the graft in autosomal dominant polycystic kidney disease with thrombophilia
Authors: Davide Rolla, Iris Fontana, Jean Louis Ravetti, Luigina Marsano, Diego Bellino, Laura Panaro, Francesca Ansaldo, Lisa Mathiasen, Giulia Storace, Matteo Trezzi
Journal: J Renal Inj Prev (2015)
Keywords: kidney transplantation, leiden factor v, protrombin gene, thrombotic miocroangiopathy
MeSH terms: Case Reports

Introduction:
Thrombotic microangiopathy (TMA) is a serious complication of renal transplantation and is mostly related to the prothrombotic effect of calcineurin inhibitors (CNIs). A subset of TMA (29%-38%) is localized only to the graft. Case 1: A young woman suffering from autosomal dominant polycystic kidney disease (ADPKD) underwent kidney transplant. After 2 months, she showed slow renal deterioration (serum creatinine from 1.9 to 3.1 mg/dl), without hematological signs of hemolytic-uremic syndrome (HUS); only LDH enzyme transient increase was detected. Renal biopsy showed TMA: temporary withdraw of tacrolimus and plasmapheresis was performed. The renal function recovered (serum creatinine 1.9 mg/dl). From screening for thrombophilia, we found a mutation of the Leiden factor V gene. Case 2: A man affected by ADPKD underwent kidney transplantation, with delay graft function; first biopsy showed acute tubular necrosis, but a second biopsy revealed TMA, while no altered hematological parameters of HUS was detected. We observed only a slight increase of lactate dehydrogenase (LDH) levels. The tacrolimus was halved and plasmapheresis was performed: LDH levels normalized within 10 days and renal function improved (serum creatinine from 9 to 2.9 mg/dl). We found a mutation of the prothrombin gene. Only a renal biopsy clarifies the diagnosis of TMA, but it is necessary to pay attention to light increasing level of LDH.
Conclusion:
Prothrombotic effect of CNIs and mTOR inhibitor, mutation of genes encoding factor H or I, anticardiolipin antibodies, vascular rejection, cytomegalovirus infection are proposed to trigger TMA; we detected mutations of factor II and Leiden factor V, as facilitating conditions for TMA in patients affected by ADPKD.
A severe myopathy case in aged patient treated with high statin dosage
Authors: Elena Canzonieri, Cristina De Candia, Salvatore Tarascio, Silvia Giamporcaro, Giovanni Lumera, iuseppe RiganoG, Carmela Incognito, Filippo Privitera, Agata Guarnaccia, Valerio Foti Pietro, Stefano Palmucci, Pietro Gangemi, Giulia Fuccio-Sanzà, Salvatore Santo Signorelli
Journal: Toxicol Rep (2017)
Keywords: enzyme, inflammatory disease, myopathy, rhabdomyolysis, statin
MeSH terms: Case Reports

Statins (S) are widely used drugs for cardiovascular prevention however their utilization may cause a various grade of muscle toxicity. Sometime S discontinuation alone is not sufficient to revert muscle injury and this can evolve in serious inflammatory muscle disease. In this case immunosuppressive medications are required to achieve remission. This case report describes a patient who developed rhabdomyolysis after recent S treatment initiation and the diagnostic work up have lead to the diagnosis of necrotizing autoimmune myopathy (NAM). We believe that the clinical case described here is a useful report of this rare toxicity and we aim to highlight the importance of its prompt recognition and treatment.
Left ventricular haematoma mimicking lateral wall myocardial infarction secondary to percutaneous coronary intervention
Authors: Omer Senarslan, Necdet Batuhan Tamci, Umut Hasan Kantarci, Mehmet Eyuboglu, Dilsad Amanvermez Senarslan
Journal: Cardiovasc J Afr (2017)
MeSH terms: Coronary Stenosis / surgery, Heart Diseases / surgery, Heart Ventricles, Hematoma / diagnosis, Myocardial Infarction / diagnosis, Percutaneous Coronary Intervention / adverse effects, Postoperative Complications, Case Reports, Diagnosis, Differential, Female, Heart Diseases / diagnosis, Heart Diseases / etiology, Hematoma / etiology, Humans, Middle Aged

Dissecting intra-myocardial haematoma is a rare disease and a potentially fatal complication after cardiac surgery. Patients with previous heart surgery have more risk for dissecting intra-myocardial haematoma after percutaneous coronary intervention. Management of this issue is challenging. We describe a rare case of a 63-year-old woman with a left ventricular wall-dissecting intra-myocardial haematoma, which developed 30 minutes after percutaneous coronary intervention. The patient was treated conservatively, with a successful outcome.
Globus Pallidus Internus Deep Brain Stimulation for Disabling Diabetic Hemiballism/Hemichorea
Authors: Byung-Chul Son, Jin-Gyu Choi, Hak-Cheol Ko
Journal: Case Rep Neurol Med (2017)
MeSH terms: Case Reports

Unilateral hemichorea/hemiballism (HH) associated with contralateral neuroimaging abnormalities of the basal ganglia, which is characterized by T1 hyperintensity on magnetic resonance imaging (MRI) and is secondary to diabetic nonketotic hyperglycemia, is a rare and unique complication of poorly controlled diabetes mellitus (DM). Although almost all prior reports have documented rapid resolution of HH within days after normalization of blood glucose levels, medically refractory persistent HH has been noted. The experience of surgical intervention for persistent HH is limited. A 46-year-old, right-handed female patient with type 2 DM presented with refractory diabetic HH on the left side of 6 months' duration despite DM control and neuroleptic medication usage. Image-guided deep brain stimulation (DBS) on the right globus pallidus internus (GPi) was performed. A mechanical micropallidotomy effect was observed and chronic stimulation of GPi was quite effective in symptomatic control of diabetic HH until a 16-month follow-up visit. DBS of the GPi can be an effective treatment for medically refractory diabetic HH.