OpenMed/multicare-articles huggingface dataset:
Arthroscopic Treatment of Chronic Cruciate Ligament Rupture in the Dog without Stifle Stabilization: 13 Cases (2001-2020)
Authors: Danielle G Creamer, Peter Muir
Journal: Case Rep Vet Med (2023)
MeSH terms: Case Reports

Objective:
The objective was to study clinical outcomes in dogs with chronic cruciate ligament rupture (CR) treated with palliative arthroscopy as the sole surgical treatment.
Methods:
Thirteen client-owned dogs with CR underwent physical examination, stifle radiography, and arthroscopy with resection of damaged meniscal tissue. Records were evaluated, and orthopaedic examination, radiographs, and arthroscopy images were assessed. Long-term clinical outcome was also assessed by use of an owner questionnaire.
Results:
Thirteen dogs that underwent arthroscopy at the UW Veterinary Care between 2001 and 2020 were included. Long-term follow-up was available for 7 of 13 dogs. Lameness was static to improved in all dogs in which arthroscopy was performed. Subsequent stifle stabilization was performed after arthroscopy in only 1 of 7 dogs with follow-up data.
Conclusion:
Palliative arthroscopy and resection of damaged meniscal tissue in combination with medical management of osteoarthritis can be considered in dogs with chronic CR and cranial tibial subluxation with little passive laxity during examination. Revision surgery with TPLO is uncommon after arthroscopy based on this study.
Drug-induced liver injury associated with dacomitinib: A case report
Authors: Xuanxuan Wang, Anqi Huang, Yun Lu, Suyu Gao, Wen Hu, Hong Cheng
Journal: Front Oncol (2022)
Keywords: roussel uclaf causality assessment method, case report, dacomitinib, drug-induced liver injury, non-small cell lung cancer
MeSH terms: Case Reports

Dacomitinib, the second-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), has been used as a first-line treatment in non-small cell lung cancer (NSCLC) patients harboring EGFR mutation. In this case, we report a patient with drug-induced liver injury (DILI) associated with the use of dacomitinib. A 59-year-old man with stage IV NSCLC was prescribed with dacomitinib; 37 days after dacomitinib administration, he was admitted to our hospital because of jaundice. Laboratory examinations revealed elevated serum levels of liver enzymes and bilirubin. Following the immediate discontinuation of dacomitinib, liver enzymes decreased but bilirubin continued to rise. Total bilirubin reached the peak (18-fold) on day 26 after dacomitinib termination and normalized on day 146 after dacomitinib discontinuation. A "probable" cause of DILI by dacomitinib was determined based on the Roussel Uclaf Causality Assessment Method. The severity of DILI was assessed as acute liver failure. To our knowledge, this is the first case of DILI caused by dacomitinib monotherapy in a real-world setting. Clinicians should pay particular attention to the possibility of DILI during dacomitinib treatment.
Orbital Cavernous Hemangioma Presenting with a Dome-Shaped Maculopathy-Like Appearance on Swept-Source Optical Tomography Imaging
Authors: Şükran Bekdemir, Ahmet Kaan Gündüz, Cevriye Cansız Ersöz
Journal: Case Rep Ophthalmol Med (2020)
MeSH terms: Case Reports

A 43-year-old patient presented with painless proptosis, limited upgaze, and vision loss in the right eye. Funduscopic examination revealed right optic disc edema and subtle macular compression. Swept-source optical coherence tomography (SS-OCT) revealed a smooth contoured elevation of the posterior pole without any distortion of retinal structures, an appearance closely simulating dome-shaped maculopathy. Swept-source optical coherence tomography angiography (SS-OCTA) revealed normal retinal and choroidal vasculature. Orbital magnetic resonance imaging demonstrated a well-circumscribed intraconal mass compressing the globe and optic nerve in the right orbit. An anterior orbitotomy was performed, whereby the tumor was totally excised and diagnosed histopathologically as cavernous hemangioma. This case represents an orbital cavernous hemangioma touching the eyeball and producing compression of the posterior pole presenting with a dome-shaped maculopathy-like appearance on SS-OCT. SS-OCT and SS-OCTA are important noninvasive tools for evaluating the retinal and choroidal effects in orbital tumors.
A Case of Lung Adenocarcinoma Originating from an Old Posttraumatic Scar in a Young Patient
Authors: Fatima Ahmed, Hassaan Yasin, Hesham E Mohamed
Journal: Case Rep Oncol Med (2019)
MeSH terms: Case Reports

A relationship between lung scarring and cancer has been recognized for many decades but more evidence is needed to strengthen this association. A 34-year-old nonsmoker male with a history of left lower lobe lung scar secondary to a pulmonary contusion from a motor vehicle accident in 2012 was admitted with shortness of breath and cough. A computed tomography (CT) angiography of the chest demonstrated bilateral pulmonary emboli, left lower lobe mass, left lung septal thickening, and mediastinal lymphadenopathy. A CT-guided biopsy of the mass was performed, and pathology was consistent with lung adenocarcinoma. Staging work-up revealed a widely metastatic disease. The patient developed severe complications requiring hospitalization after the first cycle of chemotherapy and subsequently passed away. Lung scar carcinoma originates around peripheral scars resulting from a variety of infections, injuries, and lung diseases. It has poor prognosis because it metastasizes from relatively small lesions. Our case further endorses that lung scarring can potentially lead to the development of cancer. Furthermore, we want to highlight the need to conduct studies to determine if monitoring this patient population with periodic imaging can have a survival benefit.
Replantation of immature avulsed teeth with prolonged extraoral dry storage: a case report
Authors: Shweta Jain, Vijay Agarwal, Arun Kumar Gupta, Pramod Prabhakar
Journal: Int J Clin Pediatr Dent (2012)
Keywords: avulsion, replacement resorption, replantation
MeSH terms: Case Reports

This case report presents delayed replantation of avulsed teeth after extended extraoral period and nonphysiological storage. Yet, long-term prognosis is not good, it presents alternate treatment modality to immediately restore esthetic and function as well as to promote the growth of alveolar crest for proper eruption of adjacent unaffected teeth until a definite prosthetic treatment seems appropriate. How to cite this article: Jain S, Agarwal V, Gupta AK, Prabhakar P. Replantation of Immature Avulsed Teeth with Prolonged Extraoral Dry Storage: A Case Report. Int J Clin Pediatr Dent 2012;5(1):68-71.
Infantile Extracranial Rhabdoid Tumor of the Scalp
Authors: Sura Al Rawabdeh, Deifallah Alsharari, Hayat Khasawneh, Ola M Al Waqfi, Qamar Yaser Malabeh, Hiathem Abu Alhaija, Raed Mohammad Aljubour, Hamzeh M Alkhawaldeh
Journal: Case Rep Med (2021)
MeSH terms: Case Reports

Extracranial rhabdoid tumor is a rare tumor that can originate in multiple organs, and it is most commonly seen in the kidneys. This tumor has a grave prognosis. We report to the best of our knowledge the first case of infantile scalp extracranial rhabdoid tumor in a 6-month-old male baby who presented with a right parietal scalp mass since the age of 1 month. This mass was initially diagnosed as scalp hemangioma based on clinical and imaging findings. However, this mass was growing fast which necessitated excision. Pathologic examination after excision showed a malignant tumor composed of sheets of rhabdoid cells. Immunohistochemically, this tumor tested positive for vimentin, CD 99, glypican-3, synaptopysin, WT-1, CK, and EMA. INI-1 immunostain was lost in the tumor cells. Subsequently, this tumor was pathologically diagnosed as extracranial scalp rhabdoid tumor. After tumor excision, the patient was referred to pediatric oncology to receive chemotherapy. Experience with scalp extracranial rhabdoid tumors is limited. However, this tumor in other organs carries a grave prognosis. Although scalp extracranial rhabdoid tumor is an extremely rare tumor, it should be kept in mind in the differential diagnosis of infantile scalp masses given the need of combined surgical and chemotherapeutic treatment.
Traumatic Haemorrhagic Cervical Lymphadenopathy with Underlying Infectious Mononucleosis
Authors: George Rahmani, Sarah Power
Journal: Case Rep Radiol (2017)
MeSH terms: Case Reports

A 16-year-old male presented to the Emergency Department with a painful 3 × 3 cm left-sided neck swelling six hours following blunt trauma to the neck from a heavy swinging door. A CT angiogram was performed which revealed a large haemorrhagic lymph node as well as generalised cervical lymphadenopathy. The patient was eventually diagnosed with infectious mononucleosis. This case report describes a rare case of traumatic haemorrhagic cervical lymphadenopathy with an underlying diagnosis of infectious mononucleosis.
The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure
Authors: Moustafa Mourad, Sami P Moubayed, Ilya Likhterov, Mark Urken
Journal: Case Rep Otolaryngol (2016)

Background. Recurrent glottic squamous cell carcinomas following radiation therapy for early staged tumors are oftentime early staged tumors. Management of these early stage recurrences presents a dilemma for the head and neck surgeon. Difficulties in appropriate tumor mapping, preoperative analysis, and poor understanding of the virulent pathologic nature of the recurrence may impede surgical decision-making. Methods. This is a single surgeon case report, presenting a patient with rapid recurrence following salvage transoral resection for an early stage recurrence, necessitating a total laryngectomy. Results. A review of the literature was performed, identifying studies that expound on the pathologic behavior of radiation recurrent disease. Conclusions. Radiation recurrent glottic squamous cell carcinoma has a distinct pathologic behavior and aggressive nature. Disease virulence, coupled with difficulty in appropriate staging and preoperative tumor mapping, should guide the surgeon when deciding the surgical management in the salvage setting.
Diagnosis and Management of a Unique Iatrogenic Biatrial Gerbode Defect
Authors: Karim Shuaib, Giacomo Scorsese, Christopher Seiter, Eric Zabirowicz, Jeremy Poppers
Journal: Case Rep Anesthesiol (2022)
MeSH terms: Case Reports

The Gerbode defect was first described in the late 1950s as a congenital peri-membranous ventricular septal defect (VSD), resulting in a left to right ventriculoatrial shunt. We present a case of a patient with restenosis of a prior bioprosthetic aortic valve (AV) who underwent reoperative AV replacement (AVR), which was complicated by a unique iatrogenic Gerbode defect with concurrent LV-LA communication. Our case highlights the unique complications resulting from ventriculoatrial shunts, with consideration paid to the management of ventriculoatrial defects described.
Interrupted aortic arch associated with aortic coarctation, bicuspid aortic valve and moderate to severe mitral valve regurgitation in an adult patient: a case report
Authors: Othmane Haddani, Besart Cuko, Frederic Vanden Eynden
Journal: Pan Afr Med J (2022)
Keywords: aortic arch interruption, aortic coarctation, bicuspid aortic valve, case report, congenital abnormality
MeSH terms: Aortic Coarctation / complications, Aortic Coarctation / diagnosis, Aortic Coarctation / surgery, Bicuspid Aortic Valve Disease / complications, Hypertension / complications, Mitral Valve Insufficiency / diagnosis, Mitral Valve Insufficiency / etiology, Mitral Valve Insufficiency / surgery, Case Reports, Adult, Aorta, Thoracic / abnormalities, Aorta, Thoracic / surgery, Aortic Valve / surgery, Humans, Male, Young Adult

Interrupted aortic arch is a rare congenital abnormality with a high mortality rate in infancy conditioning only a few cases reported in adult patients. The principal finding is a complete loss of continuity between the ascending and descending portions of aorta, and is usually associated with other cardiac defects. In this case report, we present a 22-year-old male patient with refractory hypertension and diagnosis of interrupted aortic arch associated with aortic coarctation, bicuspid aortic valve and moderate to severe mitral valve regurgitation. We decided to perform a surgical correction and the patient underwent to bypass grafting of the ascending-to-descending aorta, and mitral valve repair. Interrupted aortic arch must be considered in the differential diagnosis of adult patient with refractory hypertension and a careful physical examination is crucial for ensuring the correct diagnosis of rare congenital abnormality non made until adulthood.
Prolonged Disease Course of COVID-19 in a Patient with CTLA-4 Haploinsufficiency
Authors: T W Hoffman, H L Leavis, B M Smits, L T van der Veken, D A van Kessel
Journal: Case Reports Immunol (2023)
MeSH terms: Case Reports

Patients with primary immunodeficiencies are especially vulnerable to developing severe coronavirus disease 2019 (COVID-19) after infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an important regulator of immune responses, and patients who suffer from CTLA4 haploinsufficiency have hyperactivation of effector T cells and infiltration of various organs. Overexpression of CTLA4 has been associated with a more severe disease course in patients with COVID-19, but there have only been a few reports on the disease course of COVID-19 in patients with CTLA4 haploinsufficiency. We report on a 33-year-old female with a history of immune thrombocytopenia, autoimmune haemolytic anaemia, granulomatous-lymphocytic interstitial lung disease, and common variable immunodeficiency who developed COVID-19. She was admitted and discharged from the hospital several times in the months thereafter and remained symptomatic and had a positive SARS-CoV-2 PCR for up to 137 days after the first symptoms. No SARS-CoV-2 antibodies were identified in the patients' serum. The disease was finally controlled after repeated infusions of convalescent plasma and treatment of concurrent bacterial and fungal infections. Genetic analysis revealed a likely pathogenic variant in CTLA4, and CTLA4 expression on regulatory T-cells was low. This case illustrates that patients with primary immunodeficiencies who have a protracted disease course of COVID-19 could benefit from convalescent plasma therapy.
CASE REPORT Pan-Suture Synostosis After Posterior Vault Distraction
Authors: Katrina F Chu, Stephen R Sullivan, Helena O Taylor
Journal: Eplasty (2013)
Keywords: saethre-chotzen syndrome, delayed craniosynostosis, distraction osteogenesis, posterior vault distraction, secondary craniosynostosis

Objective:
Posterior vault remodeling by distraction osteogenesis is a relatively new technique used for initial correction of turribrachycephaly in children with bicoronal craniosynostosis. We present a new potential complication from this procedure; a case of pan-suture synostosis subsequent to posterior vault distraction.
Methods:
We report an infant girl who presented with bicoronal synostosis in the setting of Saethre-Chotzen syndrome. She underwent posterior vault distraction and was distracted a total of 34 millimeters, with successful osteogenesis at the site.
Results:
One year postoperatively, the patient was found to have incidental, asymptomatic pan-suture synostosis on computed tomography.
Conclusions:
To our knowledge, this is the first reported case of delayed craniosynostosis after posterior vault distraction in the literature. The possible pathogenesis and significance of this case are discussed with a review of the current literature.
Elastic band causing exfoliation of the upper permanent central incisors
Authors: Monica Ghislaine Oliveira Alves, Dárcio Kitakawa, Joao Batista Macedo Becker, Adriana Aigotti Haberbeck Brandão, Luiz Antonio Guimarães Cabral, Janete Dias Almeida
Journal: Case Rep Dent (2015)

Objective. This study reports a case in which elastic band use culminated in the loss of the incisors. Case Report. An 11-year-old white girl was seen complaining of pain, with purulent discharge and severe tooth mobility. The bone destruction detected radiographically in the region, despite its single location and absence in posterior quadrants of the maxilla and/or mandible, was similar to that observed in Langerhans cell disease. To our surprise, an elastic band involving the midportion of the roots of the two upper central incisors was found during biopsy. The debris was removed and a metal wire was placed in permanent maxillary right and left incisors. The patient was followed up, but no improvement in tooth mobility was observed. Bone loss increased, and internal resorption and root exposure occurred, which culminated in the extraction of permanent maxillary right and left incisors. Conclusion. The present case highlights the fact that professionals sometimes are confronted by anamnestic reports never seen before.
Catheter-related bacteremia due to Kocuria rosea in a patient undergoing peripheral blood stem cell transplantation
Authors: Fevzi Altuntas, Orhan Yildiz, Bülent Eser, Kürsat Gündogan, Bulent Sumerkan, Mustafa Cetin
Journal: BMC Infect Dis (2004)
MeSH terms: Actinomycetales Infections / etiology, Bacteremia / etiology, Catheterization, Central Venous / adverse effects, Micrococcaceae / isolation & purification, Peripheral Blood Stem Cell Transplantation / adverse effects, Prosthesis-Related Infections / microbiology, Case Reports, Actinomycetales Infections / microbiology, Adult, Bacteremia / microbiology, Catheters, Indwelling / microbiology, Humans, Immunocompromised Host, Male, Micrococcus, Opportunistic Infections / microbiology

Background:
Micrococcus species may cause intracranial abscesses, meningitis, pneumonia, and septic arthritis in immunosuppressed or immunocompetent hosts. In addition, strains identified as Micrococcus spp. have been reported recently in infections associated with indwelling intravenous lines, continuous ambulatory peritoneal dialysis fluids, ventricular shunts and prosthetic valves.
Case presentation:
We report on the first case of a catheter-related bacteremia caused by Kocuria rosea, a gram-positive microorganism belonging to the family Micrococcaceae, in a 39-year-old man undergoing peripheral blood stem cell transplantation due to relapsed Hodgkin disease. This uncommon pathogen may cause opportunistic infections in immunocompromised patients.
Conclusions:
This report presents a case of Kocuria rosea catheter related bacteremia after stem cell transplantation successfully treated with vancomycin and by catheter removal.
A Combined Approach for the Aesthetic Management of Stained Enamel Opacities: External Bleaching Followed by Resin Infiltration
Authors: O Marouane, N Douki, F Chtioui
Journal: Case Rep Dent (2018)
MeSH terms: Case Reports

Stained enamel opacities are frequently encountered in dental practice. However, due to the risk of unaesthetic outcome, managing such lesions by resin infiltration techniques alone is not advised. Therefore, performing external bleaching before resin infiltration procedure is mandatory to eliminate stains from the hypomineralized lesions in order to aesthetically infiltrate them. In this work, we describe clinical cases in which external bleaching and resin infiltration techniques were used for managing stained enamel hypomineralized lesions related to traumatic dental injuries and molar incisor hypomineralization. Despite the fact that this approach has some limitations, it could be concluded that external bleaching associated with the resin infiltration technique shows promising results to aesthetically manage stained enamel opacities when the stain is totally removed after bleaching.
Perianal giant condyloma acuminatum-buschke-löwenstein tumor: a case report
Authors: Sukru Tas, Muhammet Kasim Arik, Faruk Ozkul, Oztekin Cikman, Yilmaz Akgun
Journal: Case Rep Surg (2012)

Condyloma acuminatum caused by Human Papillomavirus is the most commonly occurring sexually transmitted infection in the anogenital region. Buschke-Löwenstein tumor (BLT) known also as giant condyloma acuminatum is a rare disease. The disease, for which the most important treatment method is the surgical excision, differs from normal condyloma acuminatum cases with its high degree of malignancy. The purpose of this paper is to present the case that reached huge dimensions in the perianal region and that was treated with wide resection in the literature.
Case Report: Prolonged VV-ECMO (111 Days) Support in a Patient With Severe COVID-19
Authors: Zhiheng Xu, Yonghao Xu, Dongdong Liu, Xuesong Liu, Liang Zhou, Yongbo Huang, Yimin Li, Xiaoqing Liu
Journal: Front Med (Lausanne) (2021)
Keywords: covid-19, acute respiratory disease syndrome, acute respiratory failure, extracorporeal membrane oxygenation, prolonged maintenance
MeSH terms: Case Reports

Venovenous extracorporeal membrane oxygenation (VV-ECMO) may be a lifesaving rescue therapy for patients with severe coronavirus disease 2019 (COVID-19). However, little is known regarding the efficacy of prolonged ECMO (duration longer than 14 days) in patients with COVID-19. In this case report, we report the successful use of prolonged VV-ECMO (111 days) in a 61-year-old man with severe COVID-19. Given the high mortality rate of severe COVID-19, this case provided evidence for use of prolonged VV-ECMO as supportive care in patients with severe COVID-19.
Temporal Lobe Cavernous Malformation Caused Epileptic Amnesic Episodes and Mild Cognitive Impairment
Authors: Yusuke Hirokawa, Ayataka Fujimoto, Naoki Ichikawa, Keishiro Sato, Tokutaro Tanaka, Hideo Enoki, Yoshiro Otsuki, Tohru Okanishi
Journal: Front Neurol (2019)
Keywords: alzheimer disease-like symptoms, amyloid β, cavernous malformation, epileptic amnesia, hyperexcitability of the medial temporal lobe, subdural electrode recording
MeSH terms: Case Reports

Neuropathological features in Alzheimer's disease (AD) are amyloid β (Aβ) deposits and neurofibrillary changes. AD is characterized by memory impairment and cognitive dysfunction, with some reports associating these impairments with hyperexcitability caused by Aβ in the medial temporal lobe. Epileptic seizures are known to be common in AD. We encountered a 65-year-old patient with cavernous malformation (CM) in the right temporal lobe who exhibited epileptic amnesia (EA) and AD-like symptoms. Scalp electroencephalography (EEG), including long-term video-EEG, showed no interictal discharges, but intraoperative subdural electrode (SE) recording from the right parahippocampal area showed frequent epileptiform discharges. Neuropathologically, senile plaques were found in the surrounding normal cortex of the CM. Postoperatively, the patient has remained free of EA and AD-like symptoms since total removal of the CM. This is the first surgical case report to confirm temporal lobe hyperexcitability associated with EA and AD-like symptoms.
Secondary hemochromatosis as a result of acute transfusion-induced iron overload in a burn patient
Authors: Michael Amatto, Hernish Acharya
Journal: Burns Trauma (2016)
Keywords: burn patients, iron overload, secondary hemochromatosis, transfusion
MeSH terms: Case Reports

Background:
Red blood cell transfusions are critical in burn management. The subsequent iron overload that can occur from this treatment can lead to secondary hemochromatosis with multi-organ damage.
Case presentation:
While well recognized in patients receiving chronic transfusions, we present a case outlining the acute development of hemochromatosis secondary to multiple transfusions in a burn patient.
Conclusions:
Simple screening laboratory measures and treatment options exist which may significantly reduce morbidity; thus, we believe awareness of secondary hemochromatosis in those treating burn patients is critical.