OpenMed/multicare-articles huggingface dataset:
Case Report: Mycobacterium senegalense Infection After Cholecystectomy
Authors: Huiling Zhou, Hong Yang, Fengling Gong, Shaolong Zhou, Yifeng Yang, Haidan Liu, Jijia Liu
Journal: Front Public Health (2022)
Keywords: mycobacterium senegalense, case report, infection, metagenomic next-generation sequencing, non-tuberculous mycobacterium
MeSH terms: Mycobacterium / genetics, Case Reports, Research Support, Non-U.S. Gov't, China, Cholecystectomy / adverse effects, Humans, Male, Middle Aged, Mycobacteriaceae, Mycolicibacterium senegalense

Background:

Mycobacterium senegalense is a non-tuberculous mycobacterium and is found everywhere in the environment. However, M. senegalense infection in human is extremely rare, especially in immunocompetent individuals. It is difficult to detect M. senegalense infection because its symptoms are non-specific, and routine diagnostic tests are less sensitive. It is also resistant to commonly used antibiotics. Here, we report the first case of M. senegalense infection after laparoscopic cholecystectomy in China.
Case presentation:
A 55-year-old man was admitted because of repeated infections at multiple incision sites for more than 1 year. Although routine diagnostic test results were negative, metagenomic next-generation sequencing (mNGS) identified DNA sequences of M. senegalense in tissue samples from incision sites. The presence of M. senegalense was further confirmed by polymerase chain reaction and capillary electrophoresis. After 60 days of quadruple therapy with clarithromycin, moxifloxacin, rifampicin, and oxycycline, the patient's wound healed.
Conclusion:
We believe the case findings contribute to the limited amount of knowledge about M. senegalense infection and raises awareness that this infection can result in poor wound healing, even in an immunocompetent host. Owing to a lack of early, precise diagnosis, it is difficult to treat M. senegalense infections. Based on our findings, mNGS is a sensitive diagnostic test for M. senegalense infections.
Office removal of a subglottic bread clip
Authors: David E Rosow, Si Chen
Journal: Case Rep Otolaryngol (2013)

Objective. The presence of an upper airway foreign body is an emergent, potentially life-threatening situation that requires careful but rapid evaluation and management. Organic or nonorganic material may typically be found in the pyriform sinuses or tongue base or may be aspirated directly into the tracheobronchial tree. We present here an unusual case report of a patient who accidentally ingested a plastic bread clip that was lodged in his subglottis for 15 months and report successful removal in the office under local anesthesia. Methods. Mucosal anesthesia was achieved with inhaled 4% lidocaine spray. Flexible laryngoscopic removal of the foreign body was then successfully accomplished. Results. The patient's symptoms resolved completely following removal, with no sequelae. Conclusions. Office removal of airway foreign bodies is feasible and can be safely done with adequate topical anesthesia, but great caution and emergency planning must be exercised.
Retropharyngeal Lipomatous Hamartoma: Case Report and Review of Literature
Authors: Sunil Sam Varghese, Ashish Varghese, Preethi-Anni-Mercy Paul
Journal: Iran J Otorhinolaryngol (2023)
Keywords: hamartoma, lipoma, retropharynx, stridor, trans-oral excision
MeSH terms: Case Reports

Introduction:
Lipomas of the of the head and neck region are rare, more so in the retropharyngeal space. Lipomas in this region can produce symptoms that demand surgical excision. This paper describes a case of lipomatous hamartoma of the retropharynx, which to the best of our knowledge has not yet been reported in English literature.
Case report:
A 53-year-old gentleman presented to the ENT department with snoring, voice change and stridor. Examination revealed a smooth bulge in the posterior wall of the oropharynx causing near complete obstruction of the airway. A contrast enhanced computed tomogram revealed a non-enhancing hypodense lesion in the retropharyngeal space extending from C1-C4 level, which was suggestive of a lipoma. The tumour was surgically excised trans-orally. A limited review of literature is also presented.
Conclusion:
Trans-oral approach is preferred to external approach for surgical removal of benign retropharyngeal tumours that cause obstructive symptoms, as our case. This approach is safe, effective, and associated with lesser post-operative morbidity.
Continuous chest compressions with a simultaneous triggered ventilator in the Munich Emergency Medical Services: a case series
Authors: Stefan J Schaller, Sonja Altmann, Annalise Unsworth, Gerhard Schneider, Viktoria Bogner-Flatz, Thomas Paul, Petra Hoppmann, Karl-Georg Kanz
Journal: Ger Med Sci (2019)
Keywords: cardiopulmonary resuscitation, emergency medical services, emergency therapy, ventilation, ventilators
MeSH terms: Cardiopulmonary Resuscitation / instrumentation, Emergency Medical Services / methods, Respiration, Artificial / instrumentation, Case Reports, Aged, Cardiopulmonary Resuscitation / methods, Chest Wall Oscillation / instrumentation, Chest Wall Oscillation / methods, Germany, Humans, Male, Middle Aged, Out-of-Hospital Cardiac Arrest / therapy, Respiration, Artificial / methods

Background: Mechanical chest compression devices are commonly used providing a constant force and frequency of chest compression during cardiopulmonary resuscitation. However, there are currently no recommendations on ventilation during cardiopulmonary resuscitation with a mechanical chest compression device using continuous mode. An effective method for ventilation in such scenarios might be a triggered oxygen-powered resuscitator. Methods: We report seven cardiopulmonary resuscitation cases from the Munich Emergency Medical Service where mechanical chest compression devices in continuous mode were used with an oxygen-powered resuscitator. In each case, the resuscitator (Oxylator®) was running in automatic mode delivering a breath during the decompression phase of the chest compressions at a frequency of 100 per minute. End-tidal carbon dioxide and pulse oximetry were measured. Additional data was collected from the resuscitation protocol of each patient. Results: End-tidal carbon dioxide was available in all cases while oxygen saturation only in four. Five patients had a return of spontaneous circulation. Based on the end-tidal carbon dioxide values of each of the cases, the resuscitator did not seem to cause hyperventilation and suggests that good-quality cardiopulmonary resuscitation was delivered. Conclusions: Continuous chest compressions using a mechanical chest compression device and simultaneous synchronized ventilation using an oxygen-powered resuscitator in an automatic triggering mode might be feasible during cardiopulmonary resuscitation.
Left hepatic lobe herniation through an incisional anterior abdominal wall hernia and right adrenal myelolipoma: a case report and review of the literature
Authors: Carlos M Nuño-Guzmán, José Arróniz-Jáuregui, Ismael Espejo, Jesús Valle-González, Hernán Butus, Alejandro Molina-Romo, Rodrigo I Orranti-Ortega
Journal: J Med Case Rep (2012)

Introduction:
Herniation of the liver through an anterior abdominal wall hernia defect is rare. To the best of our knowledge, only three cases have been described in the literature.
Case presentation:
A 70-year-old Mexican woman presented with a one-week history of right upper quadrant abdominal pain, nausea, vomiting, and jaundice to our Department of General Surgery. Her medical history included an open cholecystectomy from 20 years earlier and excessive weight. She presented with jaundice, abdominal distension with a midline surgical scar, right upper quadrant tenderness, and a large midline abdominal wall defect with dullness upon percussion and protrusion of a large, tender, and firm mass. The results of laboratory tests were suggestive of cholestasis. Ultrasound revealed choledocholithiasis. A computed tomography scan showed a protrusion of the left hepatic lobe through the anterior abdominal wall defect and a well-defined, soft tissue density lesion in the right adrenal topography. An endoscopic common bile duct stone extraction was unsuccessful. During surgery, the right adrenal tumor was resected first. The hernia was approached through a median supraumbilical incision; the totality of the left lobe was protruding through the abdominal wall defect, and once the lobe was reduced to its normal position, a common bile duct surgical exploration with multiple stone extraction was performed. Finally, the abdominal wall was reconstructed. Histopathology revealed an adrenal myelolipoma. Six months after the operation, our patient remains in good health.
Conclusions:
The case of liver herniation through an incisional anterior abdominal wall hernia in this report represents, to the best of our knowledge, the fourth such case reported in the literature. The rarity of this medical entity makes it almost impossible to specifically describe predisposing risk factors for liver herniation. Obesity, the right adrenal myelolipoma mass effect, and the previous abdominal surgery are likely to have contributed to incisional hernia formation.
Acute Carpal Tunnel Syndrome Secondary to Amyloidosis
Authors: Ömer Serdar Hakyemez, Fatih Arslanoğlu, Murat Birinci, Mehmet Akif Çaçan, Adnan Kara
Journal: Case Rep Orthop (2019)
MeSH terms: Case Reports

Introduction:
ACTS secondary to amyloidosis is a very rare situation in the literature, and here, we present a unique case of ACTS secondary to amyloidosis.
Case report:
A 61-year-old male patient was admitted to our hospital with complaints of numbness in the lateral half of his 1, 2, 3, and 4 fingers of his right hand. These complaints started acutely, and the patient did not have a history of trauma. His clinical examination was suitable for acute carpal tunnel syndrome.
Discussion:
Carpal tunnel syndrome, as well as acute carpal tunnel syndrome, may occur based on different causes. ACTS is very rare, especially when it is not caused by a trauma. Here, we presented a unique case of ACTS based on amyloidosis.
Conclusion:
It should be kept in mind when ACTS may occur in patients with the diagnosis of amyloidosis.
Botryoid embryonal rhabdomyosarcoma of the cervix: A case report
Authors: Alejandro Delfos Hermoza, Graziela de Macêdo Matsushita, Marcelo Henrique Dos Santos, Ronaldo Luis Schmidt, Ricardo Dos Reis, Carlos Eduardo Mattos da Cunha Andrade
Journal: Int J Surg Case Rep (2023)
Keywords: botryoid, cervix, chemotherapy, embryonal rhabdomyosarcoma, surgery
MeSH terms: Case Reports

Introduction and importance:
Rhabdomyosarcoma (RMS) is a malignant tumor that arises from embryonal skeletal muscle cells. It's responsible for 3 % of cancer cases among children aged from 0 to 14 and 1 % among adolescents and young adults aged from 15 to 19. Embryonal RMS (ERMS) is the most prevalent subtype of rhabdomyosarcoma in the female genital tract. Botryoid sarcomas are a polypoid variant of ERMS. Our objective is to describe the clinical, pathological features and the treatment of a patient diagnosed with RMS botryoid of the cervix.
Case presentation:
We report a case of a 19-year-old female patient diagnosed with botryoid RMS of the cervix. The histopathological evaluation of the cervix showed a polypoid tumor lined by squamous epithelium exhibiting a large hypocellular edematous area. It was classified as group II and stage 1, according to the IRSG multicenter studies. Cervical polypectomy was performed as an oncological surgical treatment and adjuvant chemotherapy consisting of Vincristine 1.5 mg/m2/day and Actinomycin D 0.045 mg/kg/day (VA) for 45 weeks. After 6 months of follow up, she had no evidence of recurrence.
Clinical discussion:
Cervical ERMS is a rare tumor, especially in adolescence. It's usually presents as a cervical polyp or multiple polyps. Multimodal approaches have remarkably improved the prognosis and decreased the need for radical surgery with its associated morbidity.
Conclusion:
There are a variety of treatment strategies for a rare disease such as cervical botryoid RMS. This case was approached through fertility-conserving surgery, followed by adjuvant chemotherapy and oncological clinical follow up.
Papillary Ependymoma WHO Grade II of the Aqueduct Treated by Endoscopic Tumor Resection
Authors: Andreas M Stark, Heinz-Herrmann Hugo, Arya Nabavi, H Maximilian Mehdorn
Journal: Case Rep Med (2009)
MeSH terms: Case Reports

Papillary ependymoma is a rare tumor that may be located along the ventricular walls or within the spinal cord. We report the case of a 54-year-old patient with a papillary ependymoma WHO grade II arising at the entrance of the aqueduct. The tumor caused hydrocephalus. The tumor was completely removed via a right-sided endoscopic approach with restoration of the aqueduct. The free cerebrospinal fluid passage through the aqueduct was not only visualized by endoscopy but also controlled by intraoperative high-field magnetic resonance imaging. Therefore, an additional endoscopic third ventriculostomy was unneccessary.
Hypoparathyroidism in an Egyptian child with Hutchinson-Gilford progeria syndrome: a case report
Authors: Kotb Abbass Metwalley Kalil, Hekma Saad Fargalley
Journal: J Med Case Rep (2012)

Introduction:
Hutchinson-Gilford progeria syndrome is a rare genetic disorder. It is reported to be present in one in eight million and is characterized by severe growth failure, early loss of hair, lipodystrophy, scleroderma, decreased joint mobility, osteolysis, early atherosclerosis and facial features that resemble those of an aged person. Apart from diabetes mellitus, there are no reported abnormalities of thyroid, parathyroid, pituitary or adrenal function. Here, we report the case of a 10-year-old Egyptian child with Hutchinson-Gilford progeria syndrome and hypoparathyroidism.
Case presentation:
A 10-year-old Egyptian boy was referred to our institution for an evaluation of recurrent attacks of muscle cramps, paresthesia of his fingertips and perioral numbness of two months duration. On examination, we found dilated veins present over his scalp with alopecia and frontal bossing, a beaked nose, thin lips, protruding ears, a high pitched voice with sparse hair over his eyebrows and eyelashes and micrognathia but normal dentition. His eyes appeared prominent and our patient appeared to have poor sexual development. A provisional diagnosis of progeria was made, which was confirmed by molecular genetics study. Chvostek's and Trousseau's signs were positive. He had low total calcium (5.4 mg/dL), low ionized calcium (2.3 mg/dL), raised serum phosphate (7.2 mg/dL), raised alkaline phosphatase (118 U/L) and low intact parathyroid hormone (1.2 pg/mL) levels. He was started on oral calcium salt and vitamin D; his symptoms improved with the treatment and his serum calcium, urinary calcium and alkaline phosphates level were monitored every three months to ensure adequacy of therapy and to avoid hypercalcemia.
Conclusion:
Routine checking of serum calcium, phosphorus and parathyroid hormone will help in the early detection of hypoparathyrodism among children with progeria.
Prune-Belly syndrome, a rare case presentation in neonatology: about one case in Yaounde, Cameroon
Authors: Dany Hermann Ngwanou, Emmanuel Ngantchet, Georges Pius Kamsu Moyo
Journal: Pan Afr Med J (2020)
Keywords: prune-belly syndrome, cryptorchidism, urinary tract malformation
MeSH terms: Abdominal Muscles / pathology, Cryptorchidism / etiology, Prune Belly Syndrome / diagnosis, Renal Insufficiency / etiology, Case Reports, Abdominal Muscles / diagnostic imaging, Cameroon, Fatal Outcome, Humans, Infant, Newborn, Male, Prune Belly Syndrome / physiopathology, Ultrasonography

The Prune-Belly syndrome (PBS) is a rare pathology predominating in male infants, classically manifesting with the triad including aplasia of the abdominal wall muscles, dilatation of the urinary tract, and testicular abnormalities. We report and discuss the case of a full-term male newborn, in whom clinical examination at birth revealed abdominal wall muscle hypoplasia, cryptorchidism, urinary tract dilatation and renal failure. The diagnosis was made based on physical assessment, abdominal ultra-sonographic imaging, and blood sampling of urea and creatinine. For such cases, the recommended surgical management usually consists in a sequential surgical intervention including urinary tract reconstruction, abdominoplasty, and orchidopexy. However, these could not be practiced in due time in our patient, who died on the seventh day of life because of kidney failure. The prognosis of infants with Prune-Belly syndrome may be improved by quality antenatal follow-up, to enable the early diagnosis and preparation for prompt surgical intervention.
Breast diseases in women over the age of 65 in Monastir, Tunisia
Authors: Anis Haddad, Olfa Zoukar, Amira Daldoul, Hanene Bhiri, Khechine Wiem, Houda Mhabrich, Sonia Zaied, Raja Faleh
Journal: Pan Afr Med J (2018)
Keywords: age, breast diseases, breast neoplasms, surgical procedures
MeSH terms: Abscess / epidemiology, Breast Diseases / epidemiology, Breast Neoplasms / epidemiology, Fibrocystic Breast Disease / epidemiology, Case Reports, Abscess / therapy, Aged, Aged, 80 and over, Breast Diseases / pathology, Breast Diseases / therapy, Breast Neoplasms / pathology, Breast Neoplasms / therapy, Female, Fibrocystic Breast Disease / therapy, Humans, Postoperative Complications / epidemiology, Retrospective Studies, Tunisia / epidemiology

As life expectancy is on the rise, it is predicted that a growing number of people will live beyond the age of 65 and therefore a higher number of elderly women will have breast diseases requiring significant health care and services. This study is aimed at investigating the characteristics, the treatment and outcomes of women older than 65 years old treated for breast diseases at our institution. This was a retrospective study covering the period from January 2003 to December 2011. It involved 92 patients aged over 65 and treated for breast disease in the Maternity Center of Monastir, Tunisia. The data included characteristics of patients and tumors, treatment and outcomes that were obtained through data extraction sheets. We reported a study of 92 women over the age of 65 of whom 77 women had malignant breast disease (83.6%) and 15 benign breast diseases (16.4%). Breast cancer was discovered at a mean age of 72.5 ± 6.6 years. Distant metastases were found in 5.3% of cases and infiltrative ductal carcinoma was detected in 85.7% of patients. Hormonal receptors were positive for estrogens in 64.7% of cases. Surgical treatment was performed in 73 patients and adjuvant treatment was prescribed for 67 women (86%). The complication rate was 16.6% among the 73 patients who underwent surgery. Benign breast diseases represented 16.3% of the mammary pathologies. Abscesses and fibrocystic mastopathy were the most frequent histological diagnoses. Despite great interest in geriatric gynecological pathology worldwide, many questions related to how optimally treat this patient population remain unanswered. In this study, a surgical treatment was performed in 94.8% of breast cancer patients and the complication rate was 16.6%.
Case report: Radiographic complete response of radiation-induced glioblastoma to front-line radiotherapy: A report and molecular characterization of two unique cases
Authors: Patrick T Grogan, Jeffrey J Helgager, Dustin A Deming, Steven P Howard, Robert B Jenkins, H Ian Robins
Journal: Front Neurol (2023)
Keywords: chromosomal microarray, complete response (cr), molecular sequencing, radiation, radiation-induced glioma (rig)
MeSH terms: Case Reports

Radiation-induced gliomas (RIGs) are an uncommon disease type and a known long-term complication of prior central nervous system radiation exposure, often during childhood. Given the rarity of this malignancy subtype, no clinical trials have explored optimal therapy for these patients, and the literature is primarily limited to reports of patient cases and series. Indeed, the genomic profiles of RIGs have only recently been explored in limited numbers, categorizing these gliomas into a unique subset. Here, we describe two cases of RIG diagnosed as glioblastoma (GB), IDH-wildtype, in adults who had previously received central nervous system radiation for childhood cancers. Both patients demonstrated a surprising complete radiographic response of the postoperative residual disease to front-line therapy, a phenomenon rarely observed in the management of any GB and never previously reported for the radiation-induced subgroup. Both tumors were characterized by next-generation sequencing and chromosomal microarray to identify potential etiologies for this response as well as to further add to the limited literature about the unique molecular profile of RIGs, showing signatures more consistent with diffuse pediatric-type high-grade glioma, H3-wildtype, and IDH-wildtype, WHO grade 4. Ultimately, we demonstrate that treatment utilizing a radiation-based regimen for GB in a previously radiated tissue can be highly successful despite historical limitations in the management of this disease.
Facilitating future implementation and translation to clinical practice: The Implementation Planning Assessment Tool for clinical trials
Authors: Christine P Kowalski, Linda M Kawentel, Tassos C Kyriakides, Lori Davis, Nicholas W Bowersox, Amy M Kilbourne, Grant D Huang, Andrea L Nevedal
Journal: J Clin Transl Sci (2022)
Keywords: implementation science, clinical trials, evidence-based innovations translational science, veterans

Implementation assessment plans are crucial for clinical trials to achieve their full potential. Without a proactive plan to implement trial results, it can take decades for one-fifth of effective interventions to be adopted into routine care settings. The Veterans Health Administration Office of Research and Development is undergoing a systematic transformation to embed implementation planning in research protocols through the Cooperative Studies Program, its flagship clinical research program. This manuscript has two objectives: 1) to introduce an Implementation Planning Assessment (IPA) Tool that any clinical trialist may use to facilitate post-trial implementation of interventions found to be effective and 2) to provide a case study demonstrating the IPA Tool's use. The IPA Tool encourages study designers to initially consider rigorous data collection to maximize acceptability of the intervention by end-users. It also helps identify and prepare potential interested parties at local and national leadership levels to ensure, upon trial completion, interventions can be integrated into programs, technologies, and policies in a sustainable way. The IPA Tool can alleviate some of the overwhelming nature of implementation science by providing a practical guide based on implementation science principles for researchers desiring to scale up and spread effective, clinical trial-tested interventions to benefit patients.