OpenMed/multicare-articles huggingface dataset:
Uterine scar rupture at the site of the placenta accreta presenting as a case of sudden death
Authors: Swapnil Prabhakar Akhade, Pankaj Suresh Ghormade, Ajay Bhengra, Krishnadutt Chavali, Nighat Hussain
Journal: Autops Case Rep (2020)
Keywords: cesarean section, maternal death, placenta accreta, pregnancy complications, uterine rupture
MeSH terms: Case Reports

Uterine rupture during pregnancy is a known complication of placenta accreta. This paper presents a case of sudden maternal death in the 27th week of gestation due to a ruptured uterine scar at the site of placenta accreta with a short inter-pregnancy period of 6 months with previous two C-sections. Autopsy findings revealed a massive hemoperitoneum and a thinned out anterolateral uterine wall. Internal examination revealed clotted and fluid blood in the peritoneal cavity with rupture of the anterior uterine wall at the site of the placenta accreta in a healed cesarean section scar. Placenta accreta is a rare complication of pregnancy. However, it is becoming more frequent and a significant risk factor with the increasing rate of C-section.
Benign multicystic peritoneal mesothelioma in a postmenopausal woman complicated with an ovarian cyst: a case report
Authors: Eirini-Aikaterini Evangelopoulou, Konstantinos Zacharis, Georgia Skoufi, Nikolaos Vlassis, Papamichali Roidoula, Georgios Lialios
Journal: Pan Afr Med J (2021)
Keywords: ovarian cyst, benign, case report, diagnosis, multicystic peritoneal mesothelioma
MeSH terms: Mesothelioma, Mesothelioma, Cystic / diagnosis, Mesothelioma, Cystic / surgery, Ovarian Cysts, Peritoneal Neoplasms / complications, Peritoneal Neoplasms / diagnosis, Peritoneal Neoplasms / surgery, Case Reports, Adult, Aged, Female, Humans, Postmenopause

Benign multicystic peritoneal mesothelioma is a rare cystic neoplasm, characterized by subtle symptoms, that occurs predominantly in reproductive-aged women. The pathogenesis and etiology of the disease are yet to be determined. We herein present a 71-year-old woman presented to our clinic with persistent low back pain. The clinical examination showed a palpable mass in the abdominal area. The magnetic resonance imaging revealed multiple cystic lesions that occupy the largest part of the pelvis, posterior to the uterus. The patient underwent cyst excision, total hysterectomy with bilateral salpingo-oophorectomy, omentectomy and lymph node dissection. Postoperative course was uneventful and histopathology of the specimen revealed a benign multicystic peritoneal mesothelioma. Complete tumor resection is considered the optimal therapeutic approach of peritoneal mesothelioma. Histopathological analysis is required to confirm the diagnosis of multicystic peritoneal mesothelioma.
Acute Seizures Occurring in Association With SARS-CoV-2
Authors: Sean T Hwang, Ahmad A Ballout, Usman Mirza, Anup N Sonti, Arif Husain, Claudia Kirsch, Ruben Kuzniecky, Souhel Najjar
Journal: Front Neurol (2020)
Keywords: covid-19, sars-cov-2, neurological complication, seizures, status epilepticus
MeSH terms: Case Reports

Seizures are an infrequent and serious neurological complication of SARS-CoV-2 infection, with limited data describing the etiology and the clinical context in which these occur or the associated electrographic and imaging findings. This series details four cases of seizures occurring in patients with COVID-19 with distinct time points, underlying pathology, and proposed physiological mechanisms. An enhanced understanding of seizure manifestations in COVID-19 and their clinical course may allow for earlier detection and improved patient management.
Acute coronary syndrome with non ST segment elevation myocardial infarction revealing anomalous connection of the left anterior descending artery
Authors: Abdelmajid Bouzerda, Zouhair Lakhal, Laila Bendriss, Ali Khatouri
Journal: Pan Afr Med J (2019)
Keywords: congenital coronary artery abnormalities, acute coronary syndrome, anomalous connection
MeSH terms: Acute Coronary Syndrome / physiopathology, Coronary Angiography / methods, Coronary Vessel Anomalies / diagnostic imaging, Non-ST Elevated Myocardial Infarction / physiopathology, Case Reports, Aged, Humans, Male

The occurrence of an acute coronary syndrome (ACS) with an anomalous connection of coronary artery (ANOCOR) identified as a culprit artery is very rare. This association may lead in some anatomical forms to a delay in coronary reperfusion. We report the clinical case of a patient admitted for high-risk Non ST elevation myocardial infarction (NSTEMI) in whom coronary angiography accidentally discovers an anomalous connection of the left coronary network from the right anterior. In light of this case and a review of literature, we discuss the peculiarities of these anomalous connections.
Fatal neurotoxic envenomation following the bite of a greater black krait (Bungarus niger) in Nepal: a case report
Authors: Deb Prasad Pandey, Sanjib Kumar Sharma, Emilie Alirol, François Chappuis, Ulrich Kuch
Journal: J Venom Anim Toxins Incl Trop Dis (2016)
Keywords: antivenom, bungarus niger, envenomation, krait, neurotoxicity, snakebite
MeSH terms: Case Reports

Background:
Neurotoxic envenomation following bites by kraits (Bungarus species) is a leading cause of snakebite mortality in South Asia. Over a long time, this had been attributed only to one species, the common krait (Bungarus caeruleus). However, recent research has provided increasing evidence of the involvement of several krait species. Here, we report a fatal case of neurotoxic envenomation following the bite of a greater black krait (Bungarus niger) in Nepal.
Case presentation:
A 33-year-old man was bitten in the outdoor corridor of his home in the eastern hills of Ilam district while handling a snake he thought to be non-venomous. He subsequently developed severe abdominal pain, frequent vomiting, and signs of neurotoxic envenomation leading to respiratory paralysis. The patient did not respond to Indian polyvalent antivenom given 4 h after the bite and died under treatment 8 h after the bite. This is the second time that a B. niger was observed in Nepal, the first documented case of envenomation by this species in the country and the sixth reported case worldwide.
Conclusions:
Previous distribution records - from eastern India and western Nepal, from western hills in Nepal, and from lowland localities in India and Bangladesh - indicate risk of envenomation by B. niger throughout the low and intermediate elevations of Nepal up to at least 1,500 m above sea level. As very few people in Nepal bring killed snakes to healthcare centers and because there is a general belief among local people that there are no kraits in the hills, bites by B. niger are likely to be misdiagnosed and underreported.
Spontaneous Bilateral Hemothorax as a Case of Epithelioid Hemangioendothelioma (EHE)
Authors: Essa M AlGhunaim, Hafsa AlNajem, Derar S AlShehab
Journal: Case Rep Oncol Med (2019)
MeSH terms: Case Reports

Epithelioid hemangioendothelioma (EHE) is a rare tumor that is vascular in origin, arising from the endothelial or preendothelial cells. It can occur at different sites of the body, commonly in the liver, lungs, and bone. Pulmonary EHE is usually symptomatic, sometimes presenting with a cough, dyspnea, or chest pain. Rarely, it presents with pleural effusion. Here, we are presenting a case of pleural epithelioid hemangioendothelioma presenting as a case of spontaneous bilateral hemothorax.
Atypical Fibroxanthoma: An unexpected cause of hemoptysis
Authors: Konstantinos Mantzouranis, Vasiliki Epameinondas Georgakopoulou, Serafeim Chlapoutakis, Despoina Melemeni, Christos Damaskos, Nikolaos Garmpis, Pagona Sklapani, Nikolaos Trakas, Xanthi Tsiafaki
Journal: Acta Med Litu (2021)
Keywords: atypical fibroxanthoma, hemoptysis, pulmonary metastases
MeSH terms: Case Reports

Atypical fibroxanthoma is an infrequent, low-grade superficial cutaneous neoplasm, usually presenting as a nodule or plaque of red color. It is considered as a superficial variant of pleomorphic dermal sarcoma. Although atypical fibroxanthoma has similar histologic features to pleomorphic dermal sarcoma, it has less aggressive behavior. Atypical fibroxanthoma usually occurs on sun-exposed regions of the head and neck of elderly patients. Ultraviolet light, specific genetic mutations and administration of immunosuppressive agents to transplant recipients have been associated with the pathogenesis of the tumor. The prognosis is typically excellent when treated with complete excision of the primary lesion. This report describes the rare case of a 84-year-old man with hemoptysis due to metastatic cutaneous atypical fibroxanthoma.
Acute Gastric Necrosis in a Teenager
Authors: Joseph Yorke, Frank Enoch Gyamfi, Ronald Awoonor-Williams, Ebenezer Osei-Akoto, Emmanuel Acheampong, Emmanuella Nsenbah Acheampong, Michael Ofoe Adinku, Francis Akwaw Yamoah, Thomas Okpoti Konney, Ernest Adjei, Edward Amoah Boateng, Charles Kofi Dally, Kwabena Acheamfour Ababio, Dennis Afful-Yorke, Dorcas Ahulu
Journal: Case Rep Surg (2020)
MeSH terms: Case Reports

Gastric infarction is a rare condition often associated with high mortality due to a delay in diagnosis. The stomach which has a rich supply of blood is a rare site for such a condition. Gastric infarction has a long list of etiological factors. We report a case of a patient who was managed successfully following gastric infarction from gastric dilatation. An 18-year-old female student presented with a three-day history of abdominal pain associated with abdominal distension of two days. The abdomen was distended with generalized tenderness, rebound tenderness, and guarding. Bowel sounds were absent. Digital rectal examination was unremarkable, and a pregnancy test was negative. Biochemical tests were all normal. Intraoperatively, two litres of serosanguinous fluid was suctioned from the abdomen. About 300 mL of pus was suctioned from the pelvis. The gangrenous portion was resected, and repair was done in two layers using Conell and Lambert suture techniques. Acute gastric necrosis is a rare surgical condition that requires a high index of suspicion and prompts aggressive resuscitation and surgical intervention to obviate the high mortality rate associated with the condition.
Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis
Authors: Kait Arefiev, David F Fiorentino, Lorinda Chung
Journal: Int J Rheumatol (2011)

Systemic sclerosis is a connective tissue disease characterized by fibrosis of the skin, internal organs, and widespread vasculopathy. Raynaud's phenomenon and digital ulcers are vascular manifestations of this disease and cause significant morbidity. Current treatments are only moderately effective in reducing the severity of Raynaud's in a portion of patients and typically do not lead to substantial benefit in terms of the healing or prevention of digital ulcers. Several studies have evaluated the efficacy of targeting the vasoconstrictor endothelin-1 for the treatment of systemic sclerosis-associated vascular disease. The purpose of this paper is to summarize the published studies and case reports evaluating the efficacy of endothelin receptor antagonists in the treatment of Raynaud's phenomenon and digital ulcers associated with systemic sclerosis.
Endoscopic Resection of Sinonasal Hemangiopericytoma following Preoperative Embolisation: A Case Report and Literature Review
Authors: Georg J Ledderose, Donata Gellrich, Markus Holtmannspötter, Andreas Leunig
Journal: Case Rep Otolaryngol (2013)

Objectives. Hemangiopericytoma is a rare tumor entity deriving from pericytes. Less than 5% of hemangiopericytoma occur in the nasal cavity and are characterised by a rather benign nature with low tendency of metastasis. However, as the recurrence rate in the literature ranges from 9.5% to 50%-depending on the length of followup-a radical surgical resection is considered as the gold-standard treatment. Only a few years ago, a wide external approach, usually via lateral rhinotomy or Caldwell-Luc, was performed. Endoscopic techniques were regarded as appropriate for small low-vascularised tumors only. Methods. We present the case of a 64-year-old patient with an extended sinonasal hemangiopericytoma, who was successfully treated by an endoscopic controlled endonasal tumor resection after embolisation with Onyx. Further, to support the new treatment option, we review the literature concerning all features of sinonasal hemangiopericytomas and their therapeutical management. Results/Conclusion. Onyx, which has not been described in the context of hemangiopericytoma yet, is a very effective embolic agent for a preoperative embolisation of sinonasal hemangiopericytoma allowing a safe endoscopic surgery.
Case study: persistent recovery of hand movement and tactile sensation in peripheral nerve injury using targeted transcutaneous spinal cord stimulation
Authors: Santosh Chandrasekaran, Nikunj A Bhagat, Richard Ramdeo, Sadegh Ebrahimi, Pawan D Sharma, Doug G Griffin, Adam Stein, Susan J Harkema, Chad E Bouton
Journal: Front Neurosci (2023)
Keywords: motor restoration, neuromodulation, peripheral nerve injury (pni), spinal cord stimulation (scs), tactile sensation

Peripheral nerve injury can lead to chronic pain, paralysis, and loss of sensation, severely affecting quality of life. Spinal cord stimulation has been used in the clinic to provide pain relief arising from peripheral nerve injuries, however, its ability to restore function after peripheral nerve injury have not been explored. Neuromodulation of the spinal cord through transcutaneous spinal cord stimulation (tSCS), when paired with activity-based training, has shown promising results towards restoring volitional limb control in people with spinal cord injury. We show, for the first time, the effectiveness of targeted tSCS in restoring strength (407% increase from 1.79 ± 1.24 N to up to 7.3 ± 0.93 N) and significantly increasing hand dexterity in an individual with paralysis due to a peripheral nerve injury (PNI). Furthermore, this is the first study to document a persisting 3-point improvement during clinical assessment of tactile sensation in peripheral injury after receiving 6 weeks of tSCS. Lastly, the motor and sensory gains persisted for several months after stimulation was received, suggesting tSCS may lead to long-lasting benefits, even in PNI. Non-invasive spinal cord stimulation shows tremendous promise as a safe and effective therapeutic approach with broad applications in functional recovery after debilitating injuries.
A rare cause of low back pain: report of a tailgut cyst
Authors: E A Joyce, D O Kavanagh, D C Winter
Journal: Case Rep Med (2012)
MeSH terms: Case Reports

Tailgut cysts, also known as retrorectal cystic hamartomas, are rare developmental abnormalities that typically occur in the retrorectal space. They are believed to arise from remnants of the embryonic hindgut (Hjermstad and Helwig, 1988). They can present as incidental findings during routine examination but over half of patients are thought to present with symptoms. MRI has become the modality of choice to image these frequently misdiagnosed cysts. Biopsy is not recommended. Complete intact surgical excision is advised to avoid the potential complications of these cysts which include infection, fistula formation, and the possibility of malignant transformation (Hjermstad and Helwig (1988), Mathis et al. (2010)). We describe the case of a 46-year-old female who presented with a 6-month history of low back pain. CT and MRI imaging demonstrated a complex retrorectal lesion with supralevator and infralevator components. This was removed using a combined transperineal and transabdominal approach. Histology confirmed a tailgut cyst.
Anaphylaxis to IGIV in immunoglobulin-naïve common variable immunodeficiency patient in the absence of IgG anti-IgA antibodies: successful administration of low IgA-containing immunoglobulin
Authors: Asal Gharib, Caroline Caperton, Sudhir Gupta
Journal: Allergy Asthma Clin Immunol (2016)
Keywords: anaphylaxis, cvid, case report, ivig
MeSH terms: Case Reports

Although severe reactions to immunoglobulin preparations have been frequently reported, IgE antibodies against IgA are usually not investigated; and occur predominantly in previously sensitized patients. The purpose is to report anaphylaxis to IGIV during initial infusion in a patient with common variable immunodeficiency with absent IgA without prior sensitization and in the absence of detectable IgG anti-IgA antibodies, and positive skin tests for immediate hypersensitivity to four different preparations of IGIV, one subcutaneous immunoglobulin preparation, and to purified IgA. Patient was treated without side effects with IGIV preparation depleted of IgA to which immediate hypersensitivity skin test was negative. This case demonstrates that patients with CVID with no IgA and without prior exposure to immunoglobulin or plasma may develop anaphylaxis following initial infusion of IGIV, which appears to be due to IgE anti-IgA, and independent of IgG anti-IgA antibodies. Since there is no good correlation between anaphylaxis/anaphylactic reactions and IgG anti-IgA antibodies, and IgE anti-IgA antibody test is commercially unavailable, we suggest that the patients with CVID with absence of IgA might be skin tested for immediate hypersensitivity prior to initiation of immunoglobulin administration. However, such recommendation may require studies on a large number of patients with CVID with no detectable IgA.
Cervical Whiplash Syndrome: A Case Report of a Work Accident
Authors: Maria José Costa de Almeida, Luís Almeida, Moreira Freire Duarte, Sara Alvez de Matos
Journal: Cureus (2023)
Keywords: cervical whiplash syndrome, cervicobrachialgia, muscle atrophy, occupational accident, post-traumatic bodily injury, whiplash, whiplash syndrome, work disability
MeSH terms: Case Reports

Cervical whiplash syndrome (CWS) or whiplash syndrome is a highly debated concept because there is still no consensus on its definition -- symptoms are usually very severe but the pain's root cause is typically uncertain. Clinical investigation and detailed radiology seldom identify a specific pathology. Thus, soft tissue injury is generally considered the most likely explanation for the symptoms, although it is difficult to confirm, even by MRI. We describe the clinical case of a physical education teacher who suffers an accident in one of her classes. The following day she is assessed at the emergency department and, after undergoing a radiological study of the cervical spine, she is diagnosed with straight cervical spine (kyphosis). She is observed again seven days later due to persistent pain but sent home with unchanged indications for rest and medication. After that her cervicobrachialgia progressively worsens, limiting her left shoulder active mobility and leading to associated muscle atrophy (in addition to a burnout syndrome). Several years after she is considered to have a total permanent disability. Finally, the authors propose that CWS should be approached according to the post-traumatic bodily injury evaluation methodology, suggesting some interventions.
Posterior Mediastinal Adenomatoid Tumor: A Case Report and Review of the Literature
Authors: Vishwas Parekh, Thomas Winokur, Robert J Cerfolio, Todd M Stevens
Journal: Case Rep Pathol (2016)

Adenomatoid tumor is an uncommon benign neoplasm of mesothelial differentiation that distinctively arises in and around the genital organs. In rare instances, it has been described in extragenital locations. There have been only two reports documenting its occurrence in the anterior mediastinum, and no reports documenting its occurrence in the posterior mediastinum. We report the first case of posterior mediastinal adenomatoid tumor. A 37-year-old Caucasian woman presented with symptoms of bronchitis. Imaging studies identified a 2.0 cm posterior mediastinal mass abutting the T9 vertebral body, clinically and radiologically most consistent with schwannoma. Histologic sections revealed a lesion composed of epithelioid cells arranged in cords and luminal profiles embedded in a fibrotic to loose stroma and surrounded by a fibrous pseudocapsule. Lesional cells showed vacuolated eosinophilic cytoplasm and peripherally displaced nuclei with prominent nucleoli. There was focal cytologic atypia but no mitotic figures or necrosis was identified. The lesional cells expressed cytokeratin, calretinin, and nuclear WT1 but were negative for PAX8, TTF1, p53, chromogranin, CD31, and CD34, and Ki67 showed <2% proliferation rate, diagnostic of adenomatoid tumor. Three years after resection, the patient is in good health without tumor recurrence. Thus, our encounter effectively expands the differential diagnosis of posterior mediastinal neoplastic entities.
Response of conventional chondrosarcoma to gemcitabine alone: a case report
Authors: Salvatore Provenzano, Nadia Hindi, Carlo Morosi, Mara Ghilardi, Paola Collini, Paolo G Casali, Silvia Stacchiotti
Journal: Clin Sarcoma Res (2015)
Keywords: bone sarcoma, chemotherapy, chondrosarcoma, gemcitabine, sarcoma
MeSH terms: Case Reports

Conventional skeletal chondrosarcoma is a bone neoplasm, which is poorly sensitive to anthracyclines-based chemotherapy. We report on an 18-month-long tumour response to gemcitabine as single agent in a young patient with an advanced secondary peripheral conventional chondrosarcoma, previously treated unsuccessfully with anthracyclines, ifosfamide, platinum, etoposide.
Endovascular Repair of Aortobronchial Fistula after Bentall Procedure
Authors: Dane D Gruenebaum, Ray Graf, Thomas Alexander, Sergio Tavares, Salim Surani
Journal: Case Rep Cardiol (2018)
MeSH terms: Case Reports

Aortobronchial fistula (ABF) is a rare complication of aortic repair seen with both surgical and endovascular manipulation. The available literature largely refers to the need for surgical repair. We are not aware of any reports of endovascular repair after the Bentall procedure. This report describes a patient who after the Bentall procedure presented with massive hemoptysis from ABF, a multidisciplinary team decided on endovascular repair due to patient frailty to avoid redo sternotomy. We believe this is the first case report of endovascular repair and represents the success of multidisciplinary collaboration.
Anterior mediastinal mass: a rare presentation of tuberculosis
Authors: Gopi C Khilnani, Neetu Jain, Vijay Hadda, Sudheer K Arava
Journal: J Trop Med (2011)
MeSH terms: Case Reports

We report a case of a 14-year-boy who presented to us with a low-grade fever with evening rise for 9 months. Along with this, the patient also reported a reduction in his appetite and body weight. He had a mild dry cough but no respiratory symptoms otherwise. There was no other localization for fever on history. He received antitubercular therapy, based on abnormal chest radiograph. However, there was no relief in his symptoms. General physical examination revealed mild fever. Systemic examination was unremarkable. Blood investigations done for fever were noncontributory. Computed tomographic (CT) scan of the chest revealed a mediastinal mass compressing the trachea. The possibilities of lymphoma or germ cell tumour were considered. A biopsy from the mass under CT guidance was performed. The histopathology revealed multiple epithelioid cell granulomas with necrosis, and the diagnosis of tuberculosis was made. The clinical course of this patient and the relevant literature is presented in this paper.