OpenMed/multicare-articles huggingface dataset:
Neurologic sequelae of phosphide poisoning: A case report
Authors: Sahel Shafiee Dolat Abadi, Nasim Zamani, Sahar Abbasi, Maziar Shojaei, Hossein Hassanian-Moghaddam
Journal: Front Neurol (2022)
Keywords: aluminum phosphide, brain death, brain sequelae, encephalopathy, poisoning
MeSH terms: Case Reports

Background:
Aluminum phosphide (ALP) is extremely toxic with a high mortality rate, mainly due to its cardiovascular complications. Some neurologic effects have also been reported with this pesticide.
Case presentation:
We present a 23-year-old male who presented with confusion after ingestion of a toxic dose of ALP. Computerized tomography scan demonstrated diffuse bilateral hypoattenuation of the cerebellar hemispheres, midbrain, thalamus, and globus pallidus resulting in tonsillar and transtentorial herniation and eventually brain death four days after admission.
Conclusions:
This is the first documented case of neurologic sequela following phosphide poisoning that emphasizes the importance of brain imaging studies for patients with loss of consciousness.
Measuring the unmeasurable: defining and rating precarity with the aid of EU-LFS data
Authors: Maria Symeonaki, Glykeria Stamatopoulou, Dimitrios Parsanoglou
Journal: SN Soc Sci (2023)
Keywords: entitlements, job insecurity, precarious labour, precarity, type of contract

Precarity has been established as a central theoretical issue in labour market research and numerous attempts have been made in the past to provide indicators that measure it. Precarity has also been present in political discourse and linked to specific new forms of employment (temporary, part-time, insecure, and atypical amongst others) and certain social groups often defined as vulnerable groups (youth, women, ethnic minorities). However, precarity still remains a phenomenon that needs to be quantified with the use of reliable data. The present paper aims at providing a methodology for measuring individuals that are in precarious employment with data drawn from the EU-Labour Force Survey (EU-LFS). Thus, it presents a way of identifying individuals in the core of precarity and others that belong to this set to a lesser degree. More specifically, four different levels of precarity are identified and the methodology is illustrated and tested for a specific case study, that of Greece. However, the proposed technique can be applied with no or minor modifications to other data sets of EU member states, where the common EU-LFS questionnaire is used. An effort is also made to recognise the socio-demographic characteristics of the individuals that are identified as being precarious belonging to the four levels of precarity and to specify their differences. The analysis yields that as we move from the fist level of weak precarity to the last one of strong precarity the individuals become younger, worse paid and better educated.
Supplementary information:
The online version contains supplementary material available at 10.1007/s43545-023-00651-5.
Pediatric seizure-related posttraumatic stress and anxiety symptoms treated with EMDR: a case series
Authors: Elmedina Dautovic, Carlijn de Roos, Yanda van Rood, Agnes Dommerholt, Roos Rodenburg
Journal: Eur J Psychotraumatol (2016)
Keywords: children, emdr, anxiety, epilepsy, trauma

Purpose:
To examine the potential effects of eye movement desensitization and reprocessing (EMDR) in children with epilepsy-related posttraumatic stress and/or anxiety symptoms, using a case series design.
Methods:
Five children (aged 8-18) with epilepsy identified for seizure-related posttraumatic stress and/or anxiety symptoms were treated with EMDR. To examine potential treatment effects, posttraumatic stress and anxiety symptoms were assessed (CRTI and SCARED) pre- and post-EMDR and at 3-month follow-up. Normative deviation scores were calculated to examine the severity of seizure-related posttraumatic stress and anxiety symptoms over time. The reliable change index was calculated for pre- to posttreatment change of seizure-related posttraumatic stress and/or anxiety symptoms.
Results:
Before EMDR, overall or subscale scores indicated that all children had (sub)clinical seizure-related posttraumatic stress symptoms and/or anxiety symptoms. Directly after EMDR, most children showed significant and/or clinical individual improvement, and these beneficial effects were maintained or reached at follow-up. The mean number of sessions was 2 (range 1-3, 45 min per session).
Conclusions:
In case of seizure-related posttraumatic stress and/or anxiety, this study indicates that EMDR is a potentially successful quick and safe psychological treatment for children with epilepsy.
Double Delayed Enhancement: Concomitant Cardiac Amyloidosis and Acute Coronary Embolism
Authors: Talha Ahmed, Nils P Johnson, Anju Bhardwaj, Rafael Francisco C Go, Mina F Hanna, Bihong Zhao, Danai Kitkungvan
Journal: Methodist Debakey Cardiovasc J (2021)
Keywords: cardiac amyloidosis, cardiac magnetic resonance imaging, coronary angiography, coronary embolism, delayed enhancement
MeSH terms: Amyloidosis / complications, Amyloidosis / diagnosis, Cardiomyopathies, Coronary Artery Disease, Embolism, Myocardial Infarction, Case Reports, Humans

Hereditary cardiac amyloidosis (CA) is a relatively rare cause of nonischemic cardiomyopathy. The risk of intracardiac thrombi increases significantly in patients with CA. We report a case of a patient presenting with chest pain and acute myocardial infarction who was subsequently diagnosed with concomitant CA and acute coronary embolism.
Dexmedetomidine use in the setting of cocaine-induced hypertensive emergency and aortic dissection: a novel indication
Authors: Fahad Javed, Alexandre Miguel Benjo, Kiran Reddy, Muhammad Shoaib Akram, Shahzeb Afsar Khan, Manpreet Singh Sabharwal, Girish Nadkarni, Emad F Aziz, Eyal Herzog
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

Aortic dissection is a potentially fatal but rare disease characterized by an aortic intimal tear with blood passing into the media creating a false lumen and with resultant high mortality depending on the location of dissection if not aggressively treated. Cocaine users are known to have a higher incidence of aortic dissection. We report here aortic dissection in a patient with cocaine abuse which did not respond to traditional medication regimes used currently in this setting. Worth mentioning is the use of an alpha-2 receptor selective agonist named Dexmedetomidine as a treatment modality to control hypertension in this patient, which is approved only for sedation of intubated and mechanically ventilated patients in the intensive care settings and for sedation during invasive procedures. This paper illustrates the practical beneficial role of Dexmedetomidine in controling blood pressure in the settings of cocaine-induced sympathetic surge when other treatment modalities fail.
Plantar erythrodysesthesia caused by antiretroviral treatment: a case report and review of the literature
Authors: B Aigner, K Brockow, U Darsow, J Ring, S G Plötz
Journal: Case Rep Med (2013)

Palmoplantar erythrodysesthesia is an uncommon localised cutaneous reaction to certain chemotherapeutic agents and characterized by painful palmoplantar erythema and dysesthesia. To the best of our knowledge, we report the first case of plantar erythrodysesthesia in a 40-year-old male patient receiving an antiretroviral combination therapy for HIV.
Cardiac tamponade as the initial presentation of systemic lupus erythematosus: a case report and review of the literature
Authors: Satish S Maharaj, Simone M Chang
Journal: Pediatr Rheumatol Online J (2015)
Keywords: cardiac tamponade, childhood onset, pericardial effusion, pericarditis, systemic lupus erythematosus
MeSH terms: Cardiac Tamponade / diagnosis, Cardiac Tamponade / etiology, Lupus Erythematosus, Systemic / complications, Lupus Erythematosus, Systemic / diagnosis, Case Reports, Review, Adrenal Cortex Hormones / therapeutic use, Cardiac Tamponade / drug therapy, Child, Diagnosis, Differential, Dose-Response Relationship, Drug, Echocardiography, Electrocardiography, Female, Humans, Lupus Erythematosus, Systemic / drug therapy, Pericarditis / diagnosis, Pericarditis / drug therapy, Pericarditis / etiology, Treatment Outcome, Adrenal Cortex Hormones

Systemic lupus erythematosus (SLE) is an autoimmune disease that can involve any organ system, exhibiting great diversity in presentation. Cardiac tamponade as the initial presentation of childhood onset SLE (cSLE) is rare. We report the case of a 10 year old Afro-Caribbean female who presented with complaints of chest pain, shortness of breath and fever over 4 days. Clinical examination strongly suggested cardiac tamponade which was confirmed by investigations and treated with pericardiocentesis. After a thorough investigation, the underlying diagnosis of SLE was confirmed using the Systemic Lupus International Collaborating Clinics (SLICC) criteria and high dose corticosteroid therapy initiated. A review of recent studies shows that common initial presentations of cSLE include constitutional symptoms, renal disease, musculoskeletal and cutaneous involvement. In presenting this case and reviewing the literature we emphasize the importance of cSLE as a differential diagnosis when presented with pericarditis in the presence or absence of cardiac tamponade. In these patients early diagnosis and treatment is desired and in this regard we also discuss the sensitivity of the SLICC criteria in cSLE.
Diagnosis and Management of Polyorchidism: A Case Report and Literature Review
Authors: Anthony Kanbar, Charbel Dabal, Joey El Khoury, Rami Halabi, Serge Assaf, Anthony Mina, Sabine Breidi, Maher Abdessater, Raghid El Khoury
Journal: Case Rep Urol (2023)
MeSH terms: Case Reports

Polyorchidism, or supernumerary testis, is a rare congenital abnormality of the genitourinary system. In this paper, we present the case of triorchidism in a seven-year-old asymptomatic child with a suspect left scrotal mass detected on routine physical examination. Imaging studies revealed a third testicle in the left hemiscrotum, with comparable dimensions, signal intensity on MRI, and Doppler flow on ultrasound with the ipsilateral testis. We also discuss the clinical presentations, classifications, and current diagnostic and therapeutic strategies of this condition.
Breast Cancer Metastasis in a Renal Carcinoma Pulmonary Metastasis: A Rare Example of Tumor-to-Tumor Metastasis
Authors: Áurea Lima, Isa Peixoto, Susana Sarandão, Daniel Melo, Ângelo Rodrigues, Helena Pereira
Journal: Case Rep Oncol Med (2021)
MeSH terms: Case Reports

The tumor-to-tumor metastasis phenomenon remains fairly uncommon, with fewer than 100 cases described to present time. Virtually any tumor can be a donor or a recipient neoplasm. Nevertheless, renal carcinomas have been implicated as the most common malignant tumors to harbor metastasis, while lung and breast tumors are the most frequent donors. This article reports an extremely rare case of a breast cancer metastasis in a lung metastasis of clear cell type renal cell carcinoma that met all Campbell and coworkers' tumor-to-tumor metastasis criteria. Additionally, we present the literature case reports of breast cancer metastasis in renal cell carcinomas and try to discuss the mechanisms underlying its occurrence. Since this phenomenon identification will impact the therapeutic strategy and it is not easily detected by image, the anatomopathological study of any and all suspicious lesions is of crucial importance. To the best of our knowledge, this is the first report of a metastasis inside a metastasis.
Cryptococcal Meningitis in an HIV-Negative Puerperal Woman
Authors: Tomás Robalo Nunes, Helena Pires, Liliana Alves, Ana Guerra, Susana Boavida, Ana Brito, Inês Marques, Nuno Marques
Journal: Case Rep Infect Dis (2021)
MeSH terms: Case Reports

Cryptococcal meningitis is a common opportunistic infection in HIV-infected patients and other immunocompromised people. Pregnancy, which is a state of relative immunosuppression, can also be a risk factor for the development of cryptococcal meningitis. We report a clinical case of a 41-year-old woman who developed a severe meningeal syndrome after an otherwise normal pregnancy. Cerebrospinal fluid (CSF) cytochemical analysis presented hypoglycorrhachia, high protein levels, and pleocytosis. Cryptococcal antigen tested positive in serum and CSF, and Cryptococcus neoformans was identified in the CSF culture. The diagnosis of cryptococcal meningitis was confirmed, and antifungal induction therapy was started with liposomal amphotericin B and flucytosine. After clinical improvement, induction therapy was discontinued, and the patient was discharged under maintenance therapy with fluconazole. While under antifungal maintenance therapy, the patient presented worsening of symptoms and a new brain magnetic resonance showed the development of multiple cryptococcoma. Despite sterile CSF cultures, there was a deterioration of the cytochemical parameters. The diagnosis of immune reconstitution inflammatory syndrome was assumed, and after initiation of corticotherapy, the patient improved considerably. This is a rare case of cryptococcal meningitis in a puerperal woman with a challenging management.
Case report: Liquid biopsy, the sooner the better?
Authors: Quentin Dominique Thomas, Julien Colard-Thomas, Delphine Delansay, Fanny Leenhardt, Jerome Solassol, Julie A Vendrell, Xavier Quantin
Journal: Front Oncol (2022)
Keywords: egfr, ctdna = circulating tumor dna, liquid biopsy, lung cancer, osimertinib, thrombotic microangiopathy (tma)
MeSH terms: Case Reports

The detection of circulating tumor DNA (ctDNA) by liquid biopsy is taking an increasing role in thoracic oncology management due to its predictive and prognostic value. For non-small cell lung cancer, it allows the detection of molecular mutations that can be targeted with tyrosine kinase inhibitors (TKIs). We report the case of a patient with life-threatening hepatocellular failure and thrombotic microangiopathy at the diagnosis. A salvage chemotherapy was attempted, resulting in a major worsening of her general condition and the decision to stop all anti-cancer treatment. The liquid biopsy performed at the time of immunohistochemical non-small cell lung cancer diagnosis revealed within 7 days the presence of an epidermal growth factor receptor (EGFR) DEL19 activating mutation with 736,400 DNA copies/ml of plasma. It was finally decided to attempt a treatment with osimertinib (third generation anti-EGFR TKI) despite the fact that the patient was in a pre-mortem situation. Osimertinib led to a significant and prompt improvement of her performance status after only one week of treatment. The tumor tissue genotyping performed by next-generation sequencing (NGS) was available 10 days after starting TKI treatment. It revealed in addition to the EGFR DEL19 mutation, a JAK3 and EGFR amplification, highlighting the complex interactions between EGFR and the JAK/STAT signaling pathways. The first CT-scan performed after 2 months under osimertinib showed a tumor morphologic partial response. The biological assay showed a major decrease in the EGFR DEL19 mutation ctDNA levels (40.0 copies/ml). The liquid biopsy allowed an early implementation of a targeted therapy without which the patient would probably be dead. Testing for ctDNA should be discussed routinely at diagnosis in addition to tumor tissue genotyping for patient with metastatic non-small cell lung cancer that raise the clinical profile of oncogenic addiction.
Case Report of a Triplet Pregnancy with Complete Hydatidiform Mole and Coexisting Twins
Authors: Marjorie H Thompson, Nathaniel R Miller, Shelby L Haugan, Michael C Gordon
Journal: Case Rep Obstet Gynecol (2022)
MeSH terms: Case Reports

Background:
Triplet pregnancy with complete hydatidiform mole and coexisting twin fetuses is extremely rare with an unknown incidence.
Case:
Here, we present a case report of a pregnancy with twin fetuses and concurrent hydatidiform mole that resulted in the preterm delivery of one viable baby, the unfortunate intrauterine demise of the other twin, and successful treatment of gestational trophoblastic neoplasia in the postpartum period.
Conclusion:
This case highlights several important questions that arise for women who choose to carry a multiple gestation pregnancy with complete hydatidiform mole and describes complications that can occur. It is imperative to accurately assess risks and counsel individuals who elect to carry these pregnancies to provide the best possible outcomes.
The surge of HBsAb level in a HBsAg-negative ES-SCLC patient after anlotinib plus atezolizumab treatment: A case report
Authors: Gangjun Chen, Tian Tian, Xingdong Cai
Journal: Front Oncol (2023)
Keywords: hbv functional cure, hbsab level, anlotinib, atezolizumab, small-cell lung cancer
MeSH terms: Case Reports

Small-cell lung cancer (SCLC) is a poorly differentiated neuroendocrine tumor with endocrine function. For decades, chemotherapy and immune checkpoint inhibitors (ICIs) have been the first-line treatment options. Because of its ability to normalize tumor vessels, anlotinib is recommended as a novel therapy as a third-line treatment. A combination of anti-angiogenic drugs and ICIs can effectively and safely benefit advanced cancer patients. However, immune-related side effects caused by ICIs are common. Hepatitis B virus (HBV) reactivation and hepatitis are common during immunotherapy in patients with chronic HBV infection. A 62-year-old man with ES-SCLC who had brain metastasis was described in this case. It is unusual for a HBsAg-negative patient to develop an increase in HBsAb after receiving atezolizumab immunotherapy. Although some researchers have reported the functional cure of HBV by PD-L1 antibody, this is the first case that showed a sustained increased in HBsAb level after anti-PD-L1 therapy. It is related with CD4+ and CD8+ T cells activation and HBV infection microenvironment. Importantly, this could provide a solution to insufficient protective antibody production after vaccination as well as a therapeutic opportunity for HBV patients with cancers.
Incidental Finding of Venous Air Embolism: A Case Report
Authors: Sami M Alrasheedi, Lama S Alhumaidan, Abdulmajeed A Alkhathami, Maram Alhati
Journal: Cureus (2023)
Keywords: case report, incidental finding, saudi arabia, transient cerebral ischemia, venous air embolism
MeSH terms: Case Reports

Venous air embolism (VAE) is a rare but potentially lethal condition. It has numerous clinical and physiological causes. We present a case report of a 72-year-old Saudi male, known case of diabetes mellitus (DM), hypertension, and ischemic heart disease. The patient came to the emergency room (ER) complaining of the heaviness of the tongue that resolved spontaneously within a few hours. He underwent percutaneous coronary angiography three months ago. The patient with the previously mentioned neurological symptoms, who had been misdiagnosed as having transient cerebral ischemia, was, after a computerized tomography (CT) scan result, diagnosed with venous air embolism. Venous air embolism can occur in situations other than those in which patients are traditionally thought to be at risk, making diagnosis difficult. Any sudden change in mental status and hemodynamic alterations during minimally invasive procedures should raise the physician's suspicion of VAE. Because VAE is an uncommon complication, few cases have been recorded in Saudi Arabia.
Portal hypertensive duodenopathy manifesting as "kissing" duodenal ulcers in a nigerian with alcoholic cirrhosis: a case report and brief review of the literature
Authors: Aderemi Oluyemi, Adeniyi Amole
Journal: Case Rep Med (2012)

Multiple duodenal ulcers are an uncommon finding in portal hypertensive duodenopathy (PHD). They represent a potential source of clinically significant bleeding from the upper gastrointestinal system in patients with cirrhosis. As this particular ulcer entity in relation to PHD has no distinguishing symptoms aside from those relating to the consequent bleeding, most of them are found either on routine endoscopic screening for cirrhotics or on endoscopic examination for cause(s) of bleeding in this patient population. The case documented below highlights many of the aspects of pathogenesis, associations, and consequences of this unique endoscopic finding in cirrhotic patients.
Rehabilitation of an Extremely Edentulous Atrophic Maxilla with a Pseudoskeletal Class III Relationship
Authors: Gregor-Georg Zafiropoulos, Tae Ho Yoon, Moosa Abuzayda
Journal: Case Rep Dent (2019)
MeSH terms: Case Reports

The skeletal class III relationship presents complex dentoalveolar problems, requiring multidisciplinary treatment. In edentulous people, severe atrophy of the jawbone simulates the clinical appearance of a skeletal class III relationship (pseudoskeletal class III), which presents major problems for rehabilitation. This article describes the rehabilitation of a 67-year-old patient with a pseudoskeletal class III relationship. The mandible was restored with two implant-supported bar-retained overdentures using clips for retention. The extremely atrophic maxilla was restored with a combination of sinus augmentation, implant placement, and classic prosthodontic treatment using an electroformed mesostructured overdenture with swivel lock attachments on an implant-supported bar. By performing minimal augmentative and implant surgeries and using the possibilities and advantages of classic prosthetic dentistry, the clinical situation described here could be managed and the atrophic maxilla could be rehabilitated.
Management of Total Transection of Nasoendotracheal Tube during LeFort I Osteotomy
Authors: Miles Somers, Peter Tsakiris, Peter Isert, Samuel Kim
Journal: Case Rep Anesthesiol (2020)
MeSH terms: Case Reports

Transection of the nasoendotracheal tube during orthognathic surgery is a rare, but life-threatening complication. We present a case of complete nasoendotracheal tube transection during a LeFort 1 osteotomy and discuss appropriate preventative and management techniques.
Survival Following Rectal Impalement through the Pelvic, Abdominal, and Thoracic Cavities: A Case Report
Authors: Michael Moncure, Jared A Konie, Adam B Kretzer, Peter J Dipasco, Carla C Braxton
Journal: Case Rep Med (2009)
MeSH terms: Case Reports

Impalement injuries are a unique form of penetrating trauma and are typically associated with a fall onto the object (Steele, 2006). We present the case of a 45-year-old man who reportedly slipped in his bathtub and fell onto a broomstick. Radiographic examination revealed a slender mass extending from his rectum to the right side of his neck. A review of English literature suggests that this is the second reported case in the last 100 years describing the successful management of an impalement injury traversing the pelvic, abdominal, and thoracic cavities. The management of this case is described.
Thoracoscopic Surgery for Glomus Tumor: An Uncommon Mediastinal Neoplasm and Iatrogenic Tracheal Rupture
Authors: Zhongjie Fang, Dehua Ma, Baofu Chen, Huarong Luo
Journal: Case Rep Surg (2017)
MeSH terms: Case Reports

Mediastinal glomus tumors are rarely recognized, and only seven cases have been reported in the literature. Here, we describe a rare mediastinal glomus tumor and review the characteristics of this rare clinical case. The patient was a 50-year-old female who presented with coughing for 3 months. Her chest computed tomography scan demonstrated a localized tumor in the posterior superior mediastinum. Intraoperatively, we found a longitudinal rupture of the membranous trachea above the carina. We completely resected the tumor and repaired the tracheal rupture under a thoracoscopy using a pedicled muscle flap. The tissue was diagnosed as a mediastinal glomus tumor according to its histological and immunophenotypic characteristics.