OpenMed/multicare-articles huggingface dataset:
Typical Kawasaki Disease Presenting With Pancreatitis and Bilateral Parotid Gland Involvement: A Case Report and Literature Review
Authors: Matteo Botti, Giorgio Costagliola, Rita Consolini
Journal: Front Pediatr (2018)
Keywords: kawasaki disease, fever of unknown origin, hyperamylasemia, pancreatitis, parotitis
MeSH terms: Case Reports

We describe the case of a 3-year child in which pancreatic and parotid gland involvement preceded the development of the classical clinical phenotype of a typical Kawasaki disease (KD). The child was referred to the Emergency Department with a story of 3 days of continuous fever associated with abdominal pain and bilaterally swelling in the parotid regions; laboratory evaluation identified markedly increased levels of total amylase, pancreatic amylase, lipase, and transaminase, and diagnosis of pancreatitis was posed. After 9 days of fever and persistence of the clinical features, the classical signs of KD appeared, and the child was treated with intravenous immunoglobulins (IVIG), showing a dramatic response with complete resolution of the clinical picture. In this work, we reviewed the literature about gastrointestinal (GI) symptoms in KD, focusing on pancreatic and hepatic involvement. This analysis highlighted that, in case of fever associated with pancreatic inflammation, KD must be considered in the spectrum of differential diagnosis, and that GI involvement in KD is frequently associated with an incomplete response to IVIG treatment.
Occipital pressure sores in two neonates
Authors: Yi Liu, Bin Xiao, Cheng Zhang, Zhihong Su
Journal: Burns Trauma (2015)
Keywords: head shape, local skin flap, neonates, occiput, pressure sore
MeSH terms: Case Reports

The preference for a specific head shape can be influenced by people's culture, religious beliefs and race. Modern Chinese people prefer a "talented" head shape, which is rounded and has a long profile. To obtain their preferred head shape, some parents try to change their neonates' sleeping position. Due to these forced sleeping positions, positional skull deformities, such as plagiocephaly, may be present during the first few months of life. In this article, we report two neonatal cases, of Hui nationality and Dongxiang nationality, with occipital pressure sores that were caused by using hard objects as pillows with the intention of obtaining a flattened occiput. The pressure sores were deep to the occipital bone and needed surgical management. These pressure sores caused wounds that were repaired by local skin flaps, after debridement, and the use of external constraints from a dense sponge-made head frame for approximately two weeks. One case recovered with primary healing after surgical operation. The other case suffered from a disruption of the sutured wound, and a secondary operation was performed to cover the wound. These occipital pressure sores are avoidable by providing guidance to the parents in ethnic minorities' area regarding the prevention, diagnosis and management of positional skull deformity.
Case report: Morphological changes evident after manual therapy in two cases of late-diagnosed developmental dysplasia of the hip
Authors: Christian J Fludder, Braden G Keil, Melissa J Neave
Journal: Front Pediatr (2023)
Keywords: developmental dysplasia of hip (ddh), growth and development, manual therapies, pediatrics, x-rays
MeSH terms: Case Reports

Background:
Late diagnosed Developmental Dysplasia of the Hip (DDH) is the detection of DDH after 3 months of age and is associated with significantly poorer outcomes than when diagnosed and managed early. Late diagnosed DDH has lower rates of success with bracing, higher rates of surgery and higher rates of complications, including avascular necrosis of the femoral head and early osteoarthritis of the hip. We describe two cases of late-diagnosed DDH which demonstrated changes in femoroacetabular joint morphology on radiographic interpretation after a 6-month trial period of manual therapy.
Case presentation:
Two cases (13 and 30 months of age) with late-diagnosed DDH presented to a private chiropractic clinic for conservative, non-bracing management. One case had unilateral DDH and the other bilateral DDH. A trial of manual therapy was utilized over a 6-month period. Both cases demonstrated changes to femoroacetabular morphology as well as improvements in gross motor activity and lower extremity muscle tone.
Conclusion:
Manual therapy, as an adjunct or alternative to static bracing, may be of benefit in individuals with late-diagnosed DDH not responding to bracing, and prior to more invasive interventions. Additional cases of manual therapy-based management of this condition are required to inform the design of future trials to investigate this hypothesis.
Intrastromal Corneal Ring Segment Implantation in a Patient with the Bowman Layer Inlay Transplantation for Keratoconus
Authors: João Ponces Ramalhão, Miguel Mesquita Neves, Miguel Gomes, Luís Oliveira
Journal: Case Rep Ophthalmol Med (2023)
MeSH terms: Case Reports

Keratoconus (KC) is a bilateral ectatic corneal disease which results in changes in the corneal architecture and can lead to severe visual impairment. Treatment options depend on the stage of the disease, and they aim either at improving vision or arrest progression. The Bowman layer transplantation (BLT) is a recent surgical option in patients with KC and may postpone corneal transplantation in some patients. We present a case of a 22-year-old patient with a 10-year follow-up history of progressing KC. A first attempt for an intracorneal ring segment (ICRS) implantation when he was 13 years old was unsuccessful due to a superficially implanted segment. At that time, collagen cross-linking was unavailable, and his young age raised concerns about performing a penetrating keratoplasty/lamellar keratoplasty. A BLT was performed with further ICRS implantation with relative disease stability and visual improvement. ICRS implantation in KC patients with BLT has not previously been described in literature and can be an option in selected patients.
Diagnostic and Therapeutic Implications of Organic Delusional Disorder due to Tuberculous Adrenalitis
Authors: Pooja Govind, Karthick Subramanian, Suriya Kumar
Journal: Case Rep Psychiatry (2022)
MeSH terms: Case Reports

Primary adrenal insufficiency rarely occurs due to infections, which consequently involves destruction or dysfunction of both adrenal cortices. Tuberculous adrenalitis is still a frequent cause of adrenal insufficiency in developing countries. We present the case of origin of multiple delusions along with recurrent spells of vomiting and giddiness in a patient with pulmonary tuberculosis (TB). A thorough medical history combined with a panel of biochemical and endocrine investigations revealed disseminated TB with choroid tubercles and adrenal infiltration leading to primary adrenal insufficiency. A diagnosis of organic delusional disorder secondary to disseminated TB-associated adrenal insufficiency was considered. The patient was managed with risperidone and antitubercular drugs. The psychosis improved and the patient was stable during the follow-up. The present case report adds to the literature on diagnostic challenges associated with psychosis due to adrenal insufficiency secondary to disseminated TB.
Intravascular ultrasound to guide the management of intracoronary thrombus: a case report
Authors: Italo Porto, Andrew R J Mitchell, Vaishali Ashar, Adrian P Banning
Journal: Cardiovasc Ultrasound (2004)
MeSH terms: Angioplasty, Balloon, Coronary / methods, Chest Pain / diagnosis, Coronary Stenosis / diagnostic imaging, Coronary Stenosis / surgery, Coronary Thrombosis / diagnostic imaging, Coronary Thrombosis / prevention & control, Ultrasonography, Interventional / methods, Case Reports, Adult, Chest Pain / etiology, Coronary Stenosis / complications, Coronary Thrombosis / etiology, Female, Humans, Prognosis, Surgery, Computer-Assisted / methods, Treatment Outcome

Percutaneous coronary intervention can be associated with distal embolization of thrombotic material causing myocardial necrosis and infarction. We discuss the role of intravascular imaging to guide the use of a distal protection device by describing the outcome of a young woman presenting with non-ST elevation myocardial infarction. Coronary angiography demonstrated an isolated minor stenosis in the proximal left anterior descending coronary artery with slight haziness beyond the lesion. Intravascular ultrasound confirmed an extensive thrombus overlying a bulky atherosclerotic plaque. A distal filter wire was therefore successfully used to reduce the risk of distal embolization. The use of intravascular ultrasound in patients presenting with acute coronary syndrome may reveal large thrombi that are difficult to image using conventional angiographic techniques. Intravascular ultrasound can therefore be used as a tool to select lesions requiring distal protection.
Colpodella spp.-like parasite infection in woman, China
Authors: Cong L Yuan, Patrick J Keeling, Peter J Krause, Ales Horak, Stephen Bent, Lindsay Rollend, Xiu G Hua
Journal: Emerg Infect Dis (2012)
MeSH terms: Apicomplexa / isolation & purification, Case Reports, Research Support, Non-U.S. Gov't, Anti-Infective Agents / therapeutic use, Apicomplexa / classification, Apicomplexa / genetics, Artemether, Artemisinins / therapeutic use, Female, Humans, Middle Aged, Phylogeny, RNA, Ribosomal, 18S / genetics, Tetracycline / therapeutic use, Anti-Infective Agents, Artemisinins, RNA, Ribosomal, 18S, Artemether, Tetracycline

The phylum Apicomplexa comprises intracellular protozoa that include many human pathogens. Their nearest relatives are chromerids and colpodellids. We report a case of a Babesia spp.-like relapsing infection caused by a newly described microorganism related to the Apicomplexa. This case is highly suggestive of a previously undescribed type of colpodellid that infects vertebrates.
Fatal laryngeal burn from ingestion of a hot fish cake: Case report and literature review
Authors: Michael M H Chu, Antonia Tse, Ileana Anderco, Arun Cardozo
Journal: Int J Surg Case Rep (2020)
Keywords: case report, fatal, hot food, larygeal burn, thermal epiglottitis
MeSH terms: Case Reports

Introduction:
Laryngeal burn from hot food ingestion is a rare but potentially life-threatening presentation. It is essential that clinicians have a high index of suspicion of potential airway obstruction in such cases. To our knowledge, this is the only case of fatal laryngeal oedema caused by hot solid food ingestion reported in the literature.
Presentation of case:
A 51 year old male presented to the Emergency Department complaining of a burn to the throat following ingestion of a piping hot fish cake. On initial assessment he reported only mild pain and increased saliva production. There was no evidence of stridor, dysphagia, dyspnoea or aspiration and hence the patient was discharged and advised to return if he experienced any worsening of his symptoms. 2 h later the patient collapsed at home and died due to airway obstruction from delayed laryngeal oedema.
Discussion:
27 cases of laryngeal burn from ingestion of hot food or liquid were identified in the literature. Only one fatality following ingestion of hot liquid has been reported. This is the first documented fatal laryngeal burn due to ingestion of hot solid food. At present, there are no guidelines for the assessment and management of laryngeal contact burns.
Conclusion:
Patients may be relatively asymptomatic immediately after thermal injury to the larynx. Endoscopic examination of the larynx is required to identify laryngeal oedema. Any sign of thermal injury to the laryngeal mucosa warrants admission for observation and definitive management of the airway should be considered.
Case report: 11 years on hemodialysis with a 4-year-old baby girl: A success story
Authors: Alex Tatang Mambap, Efuetnkeng Bechem, Kate Mafor Kan, Sylvain Njoyo Laah, Frida Sunjoh, Gloria Enow Ashuntantang
Journal: Front Med (Lausanne) (2023)
Keywords: bamenda, cameroon (sub-saharan africa), hemodialysis (hd), outcome, pregnancy
MeSH terms: Case Reports

Despite advances in clinical management and dialysis care, the outcome of unplanned pregnancy in women on maintenance hemodialysis (MHD) remains a difficult journey for the patient, fetus, and healthcare staff, particularly in low-resource countries. We report the successful outcome of a pregnancy in an anuric woman on twice-weekly maintenance hemodialysis for chronic glomerulonephritis since November 2012 in Cameroon. She was discovered pregnant at 18 weeks of gestation. The pregnancy was maintained until 36 weeks when a healthy 2,270 g female baby was delivered by elective cesarean section for tight nuchal cords and intrauterine growth retardation. The mother's post-partum period was uneventful. Except for hypoglycemia shortly after birth, the baby was fine. The patient is still on hemodialysis after 4 years, and the child is healthy and attending school.
Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review
Authors: Bingqian Zhang, Mingyue Zou, Zengxin Lu, Haijia Mao, Ya'nan Huang, Fang Liu, Zhenhua Zhao
Journal: Front Oncol (2021)
Keywords: case report, hepatectomy, hepatocellular tumor, pseudo-lymphoma, reactive lymphoid hyperplasia
MeSH terms: Case Reports

Reactive lymphoid hyperplasia (RLH) of the liver is a rare benign disease. This article describes a 77-year-old female patient with RLH of the liver. The patient was admitted to the hospital due to atrial fibrillation. A liver tumor was incidentally found during abdominal enhanced CT. Further magnetic resonance imaging (MRI) and PET/CT showed four lesions in the liver. The imaging findings suggested hepatocellular carcinoma (HCC), but it was not consistent that the patient had no history of liver cirrhosis and hepatitis, and a variety of tumor markers were within the normal range. The largest lesion was surgically removed and microscopically diagnosed as RLH of the liver. The pathology included a large number of reactive hyperplastic lymphoid follicles. Immunohistochemical examination showed that the infiltrating lymphocytes were polyclonal. The authors believe that the perinodular enhancement on MRI, the obvious limitation of diffusion on DWI, the insignificant increase of SUVmax on PET-CT delayed phase, and the support of clinical data can help distinguish liver RLH from lymphoma and HCC.
Attempted altruistic infanticide in a context of psychotic decompensation induced by stress linked to the COVID-19pandemic: a case report
Authors: Camille Jantzi, Alexandre Perrin
Journal: Forensic Sci Res (2021)
Keywords: covid-19, forensic sciences, criminal responsibility, forensic evaluation, forensic psychiatry, infanticide, psychosis
MeSH terms: Case Reports

The mediatization of the COVID-19 pandemic has created a lot of stress leading sometimes to mental health issues. We present a case of a thirty-year-old woman with no history of psychotic disease but some vulnerabilities and no criminal record, who attempted to kill her seven-year-old son during a brief delusional episode in the context of fear of the coronavirus. She was successfully treated by pharmacotherapy and psychotherapy. She was examined by forensic psychiatrists leading to the conclusion that her responsibility was highly diminished, and her reoffending risk was low. We add to the literature that the COVID-19 pandemic has been such a stressor for mentally vulnerable people that it could lead to severe psychiatric decompensation and even criminal acts.
Case Report: Pheochromocytoma and Synchronous Neuroblastoma in a Family With Hereditary Pheochromocytoma Associated With a MAX Deleterious Variant
Authors: Diana Borges Duarte, Lia Ferreira, Ana P Santos, Cláudia Costa, Jorge Lima, Catarina Santos, Mariana Afonso, Manuel R Teixeira, Rui Carvalho, Maria Helena Cardoso
Journal: Front Endocrinol (Lausanne) (2021)
Keywords: max gene, hereditary, neuroblastoma, paraganglioma, pheochromocytoma
MeSH terms: Adrenal Gland Neoplasms / genetics, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics, Neoplasms, Multiple Primary / genetics, Neuroblastoma / genetics, Pheochromocytoma / genetics, Case Reports, Adolescent, Adrenal Gland Neoplasms / diagnosis, Adult, Age of Onset, Family, Fatal Outcome, Genetic Association Studies, Genetic Testing, Germ-Line Mutation, Humans, Male, Neoplasms, Multiple Primary / diagnosis, Neuroblastoma / diagnosis, Pheochromocytoma / diagnosis, Portugal, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, MAX protein, human

Introduction:
Pheochromocytomas are rare catecholamine-producing neuroendocrine tumours arising from chromaffin cells of the adrenal medulla or extra-adrenal sympathetic paraganglia. Recent studies have indicated that up to 40% of pheochromocytomas could be attributable to an inherited germline variant in an increasing list of susceptibility genes. Germline variants of the MYC-associated factor (MAX) gene have been associated with familial pheochromocytomas and paragangliomas with an autosomal dominant pattern of inheritance, a median age at onset of 33 years and an overall frequency estimated at 1.9%. We describe a deleterious MAX variant associated with hereditary pheochromocytoma in a family with four affected individuals.
Case presentation:
The first patient presented with bilateral pheochromocytoma in 1995; genetic testing was proposed to his oldest son, when he was diagnosed with a bilateral pheochromocytoma with a synchronous neuroblastoma. Upon the identification of the MAX variant c.97C>T, p.(Arg33Ter), in the latter individual, his two siblings and their father were tested and the same variant was identified in all of them. Both siblings were subsequently diagnosed with pheochromocytoma (one of them bilateral) and choose to remain on active surveillance before they were submitted to adrenalectomy. All the tumours secreted predominantly norepinephrine, accordingly to the typical biochemical phenotype ascribed to variants in the MAX gene.
Conclusion:
This case series is, to our knowledge, the one with the largest number of individuals with hereditary pheochromocytoma with a deleterious MAX variant in the same family. It is also the first case with a synchronous pheochromocytoma and neuroblastoma in carriers of a MAX deleterious variant. This report draws attention to some ill-defined features of pheochromocytoma and other malignancies associated with a MAX variant and highlights the importance of understanding the genotype-phenotype correlation in hereditary pheochromocytoma and the impact of oriented genetic testing to detect, survey and treat patients and kindreds at risk.
Total endovascular repair of a malpositioneted frozen elephant trunk with Thoraflex hybrid prosthesis: A case report
Authors: Francesco Buia, Luca Di Marco, Davide Pacini, Luigi Lovato
Journal: J Cardiovasc Thorac Res (2022)
Keywords: aortic dissection, endovascular repair, frozen elephant trunk
MeSH terms: Case Reports

We report a case of a 56-year-old male who underwent Frozen Elephant Trunk procedure for residual type A chronic aortic dissection, complicated by the release of the distal endovascular portion of the hybrid prosthesis in the false lumen. This complication was successfully treated with a totally endovascular approach.
Retained Digital Flexible Ureteroscopes
Authors: Melissa Huynh, Siobhan Telfer, Stephen Pautler, John Denstedt, Hassan Razvi
Journal: J Endourol Case Rep (2017)
Keywords: complications, retained ureteroscope, ureteroscopy
MeSH terms: Case Reports

This report documents two instances of retained flexible ureteroscopes at the time of ureteroscopy and laser lithotripsy in a healthy 37-year-old male and a 53-year-old male with a pelvic kidney. We describe maneuvers to remove the ureteroscope endoscopically in the first case, while the second case required conversion to open surgery for ureteroscope extrication.
Adrenal lymphangioma mimicking renal cyst: a case report and review of the literature
Authors: Murat Akand, Mustafa Kucur, Pınar Karabagli, Ozcan Kilic, Bedreddin Seckin, Serdar Goktas
Journal: Case Rep Urol (2013)

We present a case of a 44-year-old female who was evaluated for left recurrent flank and abdominal pain. Abdominal ultrasonography demonstrated a large cystic mass on the upper pole of the left kidney. Magnetic resonance imaging showed a large, homogenous cystic mass measuring 8.5 × 9.5 cm with well-defined contours, being hypointense on T1-weighted images and hyperintense on T2-weighted images on the upper pole of the left kidney without a distinct plan between adrenal gland. According to clinical and radiological findings, surgical excision was carried out with a subcostal flank incision. Histologic and immunohistochemical examination demonstrates that the definite diagnosis is cystic lymphangioma of the left adrenal gland. Adrenal lymphangioma is a very rare lesion. This is the unique case of an adrenal lymphangioma considered as a renal cyst because of its radiological appearance.
Bilateral simultaneous nonarteritic anterior ischemic optic neuropathy after ingestion of sildenafil for erectile dysfunction
Authors: Anna Tarantini, Alessandra Faraoni, Francesca Menchini, Paolo Lanzetta
Journal: Case Rep Med (2012)
MeSH terms: Case Reports

Purpose. To describe a patient who developed bilateral, simultaneous nonarteritic anterior ischemic optic neuropathy (NAION) after ingestion of Sildenafil citrate (Viagra) for erectile dysfunction. Methods. Observational case report. Results. A 60-year-old diabetic man noted sudden decrease of vision in both eyes 16 hours after his third consecutive 50 mg daily Sildenafil ingestion. A diagnosis of bilateral NAION was made and he was treated for three days with methylprednisolone 1 g/d intravenously, followed by oral prednisone 75 mg/d. Final visual acuity was 20/50 right eye (OD) and 20/20 left eye (OS). He had preexisting diabetes. Conclusion. This is the first reported case of simultaneous bilateral NAION occurred in a diabetic patient early after Sildenafil intake. Patients with predisposing conditions such as diabetes have to be warned against the use of PDE inhibitors.
Transmission of pancreatic adenocarcinoma by a single multiorgan donor to two kidney transplant recipients: A case report
Authors: Tanja Belčič Mikič, Gregor Mlinšek, Manca Oblak, Aljoša Kandus, Jadranka Buturović-Ponikvar, Simon Hawlina, Tomaž Milanez, Nika Kojc, Maja Frelih, Miha Arnol
Journal: Front Med (Lausanne) (2023)
Keywords: cancer transmission, donor cancer, everolimus, kidney transplantation, protocol biopsy
MeSH terms: Case Reports

We present two cases of transmission of a pancreatic adenocarcinoma from a single donor to two kidney transplant recipients. Autopsy of the donor revealed a pancreatic adenocarcinoma that had already spread locally to the regional lymph nodes and had not been detected at the time of organ procurement. Both recipients were carefully monitored, as neither consented to graft nephrectomy. In one patient, the tumor was discovered on surveillance biopsy of the graft approximately 14 months after transplantation, and in the second patient, ultrasound-guided aspiration needle biopsy of a growing formation in the lower pole of the graft revealed poorly differentiated metastatic adenocarcinoma. Both patients were successfully treated with graft nephrectomy and complete discontinuation of immunosuppression. None of the follow-up imaging showed persistent or recurrent malignancy, and both patients were candidates for re-transplantation. These exceptional cases of donor-derived pancreatic adenocarcinoma suggest that removal of the donor organ and restoration of immunity may lead to complete recovery.