OpenMed/multicare-articles huggingface dataset:
Astounding Fibro Lipoma of Spermatic Cord: A Diagnostic Dilemma
Authors: Gupta Rohit, Chinniahnapalaya Pandurangaiah Hariprasad, Shreekant Bharti, Anil Kumar, Shiv Shankar Paswan, Surya Vikram, Atul Anand, Jijo Anto
Journal: Case Rep Surg (2021)
MeSH terms: Case Reports

Background:
Fibro lipoma of the spermatic cord is a very rare tumor with few cases reported in literature. Atypical presentation and site of swelling mystifies the diagnosis and creates bewildering situation intraoperatively. Case Summary. A 30-year-old farmer presented with an elastic firm nonreducible, nontender swelling at inguinoscrotal region with positive cough impulse and history of laparoscopic inguinal hernia repair 3 years ago. Ultrasonography of the swelling revealed a heteroechoic lesion of size 7 × 6 centimeter with probable features of lipoma or desmoid. Fine needle aspiration drawn in consideration of the diagnostic dilemma reported a benign lipomatous swelling which on final histopathology turned out to be a fibro lipoma of size 7 × 6 × 5 cm.
Conclusion:
Considering the age and presentation of the patient, it was astonishing. It provided an insight to the occurrence of fibro lipoma even in younger age group which in fact is the first case of its kind as per best of our knowledge. Malignancy should be ruled out in such cases, and complete excision is the treatment of choice.
Placental Teratoma Presenting as a Lobulated Mass behind the Neck of Fetus: A Case Report
Authors: Adiga Prashanth, Rai Lavanya, K M Girisha, Anjali Mundkur
Journal: Case Rep Obstet Gynecol (2012)

Placental teratoma is a rare nontrophoblastic benign tumour, which is thought to arise from germ cells. These tumours contain elements derived from multiple germ cell layers. We report a case of teratoma, where on ultrasound; there were two echogenic masses of 4 cm × 5 cm and 3 cm × 4 cm, arising from the placenta. Elective lower segment cesarean section was done in view of breech presentation at 38 weeks of gestation. Gross examination of the placenta showed two lobulated masses of 5 cm × 5 cm and 4 cm × 4.5 cm, respectively. Histopathological examination of the placenta was suggestive of teratoma of the placenta. The fetus was normal.The maternal and fetal outcome was good.
Paraganglioma of Urinary Bladder Managed by Laparoscopic Partial Cystectomy in Conjunction with Flexible Cystoscopy: A Case Report
Authors: Hossam S El-Tholoth, Sami Al Rasheedi, Faris Alharbi, Waleed Alshammari, Tarek Alzahrani, Ahmed Al Zahrani
Journal: J Endourol Case Rep (2018)
Keywords: cystoscopy, laparoscopic partial cystectomy, paraganglioma of urinary bladder
MeSH terms: Case Reports

Background: Paraganglioma of the urinary bladder (PUB) is exceedingly rare, accounting for <0.1% of all urinary bladder tumors. Various challenging treatment options are available. Case Presentation: A 67-year-old female presented with malignant hypertension on four medications for which investigation was done. An observation of having functioning PUB was noted. She was admitted and laparoscopic partial cystectomy was done with the guidance of flexible cystoscopy. She had a smooth postoperative course and was discharged home, then catheter was removed after cystogram. Histopathology confirmed the diagnosis of a bladder paraganglioma. Finally, during the last follow-up, the patient was asymptomatic with controlled blood pressure and normalized catecholamine levels with no evidence of recurrence. Conclusion: PUB is an exceedingly rare tumor that can be managed with minimally invasive techniques such as laparoscopic partial cystectomy with cystoscopy guidance.
Posterior Reversible Encephalopathy Syndrome Associated With Anlotinib: A Case Report and Literature Review
Authors: Di Nan, Xiang Yin, Di Ma, Xiaoyu Jiang, Baihua Wu, Jiachun Feng
Journal: Front Neurol (2021)
Keywords: adverse effects, anlotinib, case report, posterior reversible encephalopathy syndrome, targeted therapy
MeSH terms: Case Reports

Posterior reversible encephalopathy syndrome (PRES) is a relatively rare clinical disease, characterized by reversible subcortical vasogenic edema. Here, we present the first reported case of PRES induced by anlotinib, a multi-target tyrosine kinase inhibitor. A 56-year-old female patient with lung adenocarcinoma and bone metastasis experienced hypertension and mental confusion when she received anti-angiogenesis treatment. PRES was diagnosed after magnetic resonance of the patient's brain revealed hyperintensities bilaterally around the cerebellum, pons, fronto-parieto-occipital areas, and corona radiate. Diffusion-weighted imaging showed hyperintensities bilaterally in the parieto-occipital cortical regions. Subsequently, the patient was diagnosed with PRES, and remission was achieved with anti-hypertensive drugs. Six cases of rare adverse effects induced by anlotinib were reviewed in the literature. Since anlotinib has been widely applied as a novel third-line treatment in patients with non-small-cell lung cancer, the association between PRES and anlotinib would benefit neurologists and oncologists in future diagnoses and treatment.
Removal of Wall-Adherent Inferior Vena Cava Thrombus with a Combined Approach Using Vacuum-Assisted Thrombectomy and a Rotational Thrombectomy Device
Authors: Julius Kaemmel, Roland Heck, Pia Lanmüller, Volkmar Falk, Christoph Starck
Journal: Case Rep Vasc Med (2023)
MeSH terms: Case Reports

Introduction. Large thrombi in the inferior vena cava pose a high risk for a pulmonary embolism. Percutaneous extracorporeal circulation-based vacuum-assisted thrombus aspiration is a viable option for removal. Wall adherence of thrombotic material can compromise procedural success. Case Report. A 46-year-old female presented with a subtotal thrombotic occlusion of the inferior vena cava and the proximal right common iliac vein after weaning from extracorporeal life support. Due to severe wall adherence of the thrombotic material, the patient was treated with the combination of percutaneous extracorporeal circulation-based thrombus aspiration using the AngioVac system and a rotational thrombectomy device.
Unpredictable Outcomes of a Regenerative Endodontic Treatment
Authors: Zahra Mohammadi, Hadi Assadian, Behnam Bolhari, Mohammadreza Sharifian, Mehrfam Khoshkhounejad, Nazanin Chitsaz
Journal: Case Rep Dent (2021)
MeSH terms: Case Reports

Regenerative endodontic treatment (RET) is a valuable treatment for necrotic immature teeth with many advantages such as increasing root length and thickness of root wall. The success of RETs is based on healthy stem cells, suitable scaffolds, and growth factors and takes place when bacterial contamination is well controlled. The aim of this article is to address controversy in a case with multiple success criteria. This paper reports a 9-year-old boy with a complicated crown fracture of the maxillary left central incisor about three years prior to referral with a diagnosis of intrusive luxation with spontaneous reeruption. The tooth had an underdeveloped root and a well-defined periapical radiolucent lesion around the root apex. RET was considered according to the stage of root development. Upon the three-week recall session, the clinical examination indicated that the patient was asymptomatic in the affected site. However, the patient returned two weeks later with a sinus tract pertaining to the apex of tooth #9. Therefore, debridement of the root canal space was repeated and the RET redone. On the second trial, the patient was symptom-free, but no more evidence of root maturation was observed on 18-month follow-up. The tooth was asymptomatic (without swelling, drainage, and pain) during this time, and esthetics was provided for the patient.
Case Report: CNNM2 Mutations Cause Damaged Brain Development and Intractable Epilepsy in a Patient Without Hypomagnesemia
Authors: Xiucui Li, Shijia Bao, Wei Wang, Xulai Shi, Ying Hu, Feng Li, Qianlei Zhao, Feixia Zheng, Zhongdong Lin
Journal: Front Genet (2021)
Keywords: cnbh domain, cnnm2, hypomagnesemia, intellectual disability, intractable epilepsy
MeSH terms: Case Reports

A series of neurological manifestations such as intellectual disability and epilepsy are closely related to hypomagnesemia. Cyclin M2 (CNNM2) proteins, as a member of magnesium (Mg2+) transporters, were found along the basolateral membrane of distal renal tubules and involved in the reabsorption of Mg2+. Homozygous and heterozygous variants in CNNM2 reported so far were responsible for a variable degree of hypomagnesemia, several of which also showed varying degrees of neurological phenotypes such as intellectual disability and epilepsy. Here, we report a de novo heterozygous CNNM2 variant (c.2228C > T, p.Ser743Phe) in a Chinese patient, which is the variant located in the cyclic nucleotide monophosphate-binding homology (CNBH) domain of CNNM2 proteins. The patient presented with mild intellectual disability and refractory epilepsy but without hypomagnesemia. Thus, we reviewed the literature and analyzed the phenotypes related to CNNM2 variants, and then concluded that the number of variant alleles and the changed protein domains correlates with the severity of the disease, and speculated that the CNBH domain of CNNM2 possibly plays a limited role in Mg2+ transport but a significant role in brain development. Furthermore, it can be speculated that neurological phenotypes such as intellectual disability and seizures can be purely caused by CNNM2 variants.
Dercum's Disease: A Case Report of a Patient Having Both Type 1 and Type 2 Dercum's Disease
Authors: Cameron Moattari, Richard A Giovane, Stephanie DiGiovanni Kinsely
Journal: Case Rep Dermatol Med (2020)
MeSH terms: Case Reports

Dercum's disease, or adiposis dolorosa, is a rare disorder which consists of multiple, painful lipomas within the subcutaneous tissue and has a distribution mainly in the abdomen and extremities. Dercum's disease can be defined as in combination with chronic painful adipose tissue. Although the etiology of Dercum's disease is not clear, it is thought to be a combination of a neurological and endocrine disorder. Treatment for this disease is centered at managing pain. Although there is no standard of care for managing pain, there are different pain management regimes that are promising.
Co-Occurrence of Rarest Type of Dysphagia Lusoria (Type N-1) and Eosinophilic Esophagitis in a Cognitively Disabled Individual
Authors: Kishore Kumar, Jasbir Makker, Hassan Tariq, Ariyo Ihimoyan, Chime Chukwunonso, Masooma Niazi, Michael Lombino, Muhammad Kamal, Harish K Patel
Journal: Case Rep Med (2019)
MeSH terms: Case Reports

Dysphagia is an expressive symptom, described by an individual as "difficulty in swallowing." Dysphagia due to esophageal compression from an aberrant right subclavian artery is rare, and it is termed as "dysphagia lusoria." We present a rare case of co-occurrence of dysphagia lusoria with esophageal eosinophilia in a patient with cognitive disability which portends a case with diagnostic challenge and treatment dilemma. A 31-year-old man with intellectual disability, cerebral palsy, previous history of feeding difficulty, and esophageal food impaction presented with esophageal foreign body impaction. He has no known history of atopy and food allergies. There was no laboratory evidence of peripheral eosinophilia. The IgE-mediated allergic test was unremarkable. His prior presentation revealed a diagnosis of eosinophilic esophagitis. The imaging studies showed proximal esophageal dilatation with extrinsic compression at the level of the upper esophagus. The foreign bodies were removed successfully through the help of upper endoscopy. Subsequent evaluation revealed a rare type of dysphagia lusoria (type N-1) due to an aberrant left subclavian artery arising from the right-sided aortic arch. The patient's family refused further management of artery lusoria. Prolonged stasis of secretions and food in the esophagus can also lead to increased esophageal eosinophils. In our case, it remains undetermined whether increased number of esophageal eosinophils resulted from primary eosinophilic esophagitis or due to prolonged food stasis from esophageal compression caused by an aberrant subclavian artery. However, food impaction right above the compression site makes dysphagia lusoria the likely etiology.
The Cognitive Neuroplasticity of Reading Recovery following Chronic Stroke: A Representational Similarity Analysis Approach
Authors: Simon Fischer-Baum, Ava Jang, David Kajander
Journal: Neural Plast (2017)
MeSH terms: Cognition / physiology, Neuronal Plasticity / physiology, Reading, Recovery of Function / physiology, Stroke / diagnostic imaging, Case Reports, Research Support, Non-U.S. Gov't, Aphasia / diagnostic imaging, Aphasia / etiology, Humans, Magnetic Resonance Imaging / methods, Male, Middle Aged, Stroke / complications

Damage to certain left hemisphere regions leads to reading impairments, at least acutely, though some individuals eventually recover reading. Previous neuroimaging studies have shown a relationship between reading recovery and increases in contralesional and perilesional activation during word reading tasks, relative to controls. Questions remain about how to interpret these changes in activation. Do these changes reflect functional take-over, a reorganization of functions in the damaged brain? Or do they reveal compensatory masquerade or the use of alternative neural pathways to reading that are available in both patients and controls? We address these questions by studying a single individual, CH, who has made a partial recovery of reading familiar words following stroke. We use an fMRI analysis technique, representational similarity analysis (RSA), which allows us to decode cognitive function from distributed patterns of neural activity. Relative to controls, we find that CH shows a shift from visual to orthographic processing in contralesional regions, with a marginally significant result in perilesional regions as well. This pattern supports a contralesional reorganization of orthographic processing following stroke. More generally, these analyses demonstrate how powerful RSA can be for mapping the neural plasticity of language function.
A Particular Use of Endobag®: Extraction of Rectal Foreign Bodies
Authors: G Terrosu, V Cherchi, S Calandra, A Esposito, M Marino, D Berretti, A Risaliti
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

Introduction:
The incidence of foreign bodies (FBs) in the rectum has recently increased. FB removal by the transanal way or by colonoscopy is generally feasible and only in few cases surgery is strictly necessary. Due to FB dimensions or rectum and colon anatomy, sometimes it may represent a challenge.
Materials and methods:
Two cases of FB inserted in the rectum were treated in our institute. They underwent surgery using Endobag, a laparoscopic surgical device. The device was inserted through the anus in order to catch and remove the FB.
Results:
Both the procedures were easily performed, without any complication.
Conclusions:
The use of Endobag seems to be a good and effective way to remove FB from rectum.
Non-pregnancy-related ovarian vein thrombosis: A rare cause of chronic abdominal pain
Authors: Shaikha D Al-Shokri, Sundus Sardar, Fathima Shajeedha Ameerudeen, Mohammed Abdul Moqeeth
Journal: Qatar Med J (2021)
Keywords: abdominal pain, idiopathic, ovarian vein thrombosis, right lower quadrant abdominal pain
MeSH terms: Case Reports

Background:
Ovarian vein thrombosis (OVT) commonly occurs during the peripartum and postpartum period. However, few cases of idiopathic OVT unrelated to pregnancy have been described.
Case report:
We report a case of a previously healthy, 32-year-old female who presented with chronic right-sided abdominal pain. Abdominal and pelvic gadolinium-enhanced MRI showed a right OVT. The patient was not in the peripartum or postpartum period. Thrombophilia test results were negative, and no risk factors for thrombosis were noted. The patient received warfarin for 6 months, with resolution of her symptoms.
Conclusion:
The presented case emphasizes the significance of considering OVT as a cause of unexplained abdominal pain in a young female. We describe a rare case of idiopathic OVT with a unique presentation.
Left transperitoneal adrenalectomy with a laparoendoscopic single-site surgery combined technique: initial case reports
Authors: Yasuhiro Sumino, Daisaku Nakano, Ken-Ichi Mori, Takeo Nomura, Fuminori Sato, Hiromitsu Mimata
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

Laparoendoscopic single-site surgery (LESS) is a step toward the development of minimally invasive surgery. It is initially difficult for surgeons with limited experience to perform the surgery. We describe two cases of left adrenalectomy with a LESS combined with the addition of an accessory port. After a 2.5-cm skin incision was made at the level of the paraumbilicus to insert the primary 12-mm trocar for the laparoscope, a 5-mm nonbladed trocar was placed through the skin incision side-by-side with the primary trocar. A second 3-mm nonbladed trocar was then placed along the anterior axillary line; a multichannel trocar was not used as a single port. Both adrenalectomies were completed successfully. In patients with a minor adrenal tumor, a combined technique using LESS and an additional port is easier than LESS alone and may, therefore, be a bridge between the conventional laparoscopic approach and LESS.
Microsurgical Treatment of a Giant Intracavernous Carotid Artery Aneurysm in a Pediatric Patient: Case Report and Literature Review
Authors: Edgar Nathal, Javier Degollado-García, Alfredo Bonilla-Suastegui, Héctor A Rodríguez-Rubio, Bill Roy Ferrufino-Mejia, Martin Roberto Casas-Martínez
Journal: Cureus (2023)
Keywords: bypass, cavernous sinus aneurysm, intracavernous carotid artery aneurysm, pediatric neurosurgery, trapping, vascular neurosurgery
MeSH terms: Case Reports

Intracranial aneurysms in children account for 4%-5% of all cases, with 20% being considered giant (>25 mm). The main sites of occurrence are the internal carotid artery (ICA) and the middle cerebral artery (MCA). Rupture and secondary subarachnoid hemorrhage occur in approximately 55%-72.5% of cases, with a 10%-23% mortality rate. We report the case of a previously healthy nine-year-old girl who developed sudden, severe right retroocular pain and a holocranial headache as a mode of onset. Besides, the patient presented with double vision, and her relatives sought medical attention. Paresis of the right III, IV, and VI cranial nerves was found at physical examination. An MRI and digital subtraction angiography showed the presence of a giant aneurysm in the cavernous portion of the ICA with a mass effect. The patient was treated surgically through a high-flow bypass using a radial artery graft and trapping of the aneurysm. She had an uneventful postoperative course and was discharged three days after the operation to continue follow-up at the outpatient clinic. The therapeutic options were: a) an endovascular approach using flow diverters or stenting and coiling; or b) surgical treatment with proximal closure of the ICA if the patient had good collateral circulation or trapping the aneurysm combined with a high-flow bypass if the collateral circulation was not good or absent. After discussion, we decided on the surgical option. Even when the surgery was successful in this case, there is no consensus about the best way to treat it; the selection should be based on the center´s experience when confronting this rare entity.
Lornoxicam Side Effects May Lead to Surgical Mismanagement, in Case of Postoperative Intra-Abdominal Collection: A Case Report and Literature Review
Authors: Mohammad Bukhetan Alharbi
Journal: Case Rep Surg (2015)

Postoperative collection is a known complication of abdominal surgery, especially after major surgery; however, minor surgical procedures may also be associated with this phenomenon. Utilization of nonsteroidal anti-inflammatory drugs, such as lornoxicam, and the adverse effects thereof, may affect the surgeon's judgment regarding the need for, and extent of, draining of these collections. Here I report the case of a 25-year-old male who presented with perforated acute retrocaecal subhepatic appendicitis complicated by pleural effusion and a small abdominal collection. The pleural effusion resolved almost completely over time. However, the patient showed incomplete recovery, as demonstrated by nausea, vomiting, and mood disturbance along with abdominal pain, tachycardia, and a persistent small abdominal collection. We initially suspected infection caused by a highly virulent type of bacteria and planned to perform percutaneous drainage. However, owing to skin erythematic changes, administration of lornoxicam was ceased, which resulted in complete recovery of the symptoms and consequently in avoidance of unnecessary invasive intervention to drain the abdominal collection. These findings suggest that the utilization and adverse effects of some painkillers for postoperative pain, such as lornoxicam, may affect the surgeon's judgment regarding the most appropriate surgical workup in cases of postoperative fluid collection.
Acute corneal hydrops mimicking infectious keratitis as initial presentation of keratoconus in a 10-year-old child
Authors: Elise A Slim, Elias F Jarade, Bilal M Charanek, Joelle S Antoun, Adib I Hemade, Sahar H Awada, Henry W Fakhoury, Carole G Cherfan
Journal: Case Rep Ophthalmol Med (2015)

Purpose. To report a case of acute hydrops in a 10-year-old child with advanced keratoconus. Case Presentation. A ten-year-old boy diagnosed as having right eye (RE) infectious keratitis, not responding to antimicrobial therapy, was referred to our hospital. The diagnosis of infectious keratitis was established one month prior to his presentation following an episode of acute corneal whitening, pain, and drop in visual acuity. Topical fortified antibiotics followed by topical antiviral therapy were used with no improvement. Slit lamp examination showed significant corneal protrusion with edema surrounding a rupture in Descemet's membrane in the RE. The diagnosis of acute corneal hydrops from advanced keratoconus was highly suspected and confirmed with corneal topography. Conclusion. Although a relatively rare disease at the age of 10 years, keratoconus can be rapidly progressive in the pediatric group. Keratoconus should always be considered in the differential diagnosis of progressive vision loss in this age group.
Alveolar ridge preservation using leukocyte and platelet-rich fibrin: a report of a case
Authors: Mogammad Thabit Peck, Johan Marnewick, Lawrence Stephen
Journal: Case Rep Dent (2011)
MeSH terms: Case Reports

In order for a dental implant to be restored optimally, it must be placed in an ideal anatomic position. However, this is not always possible, since physiological wound healing after tooth removal, often results in hard and soft tissue changes which ultimately compromises ideal implant placement. With the aim of minimising the need for tissue augmentation, several alveolar ridge preservation (ARP) techniques have been developed. These often require the use of grafting material and therefore increase the risk of disease transmission. Leukocyte and platelet-rich fibrin (L-PRF) is a newly developed platelet concentrate that is prepared from the patient's own blood. Clinical research has indicated that it improves wound healing and stimulates bone formation. We present a case where L-PRF was successfully used in an ARP procedure to facilitate implant placement in a compromised extraction socket.