OpenMed/multicare-articles huggingface dataset:
Treatment of lumbar brucella spondylitis with negative pressure wound therapy via extreme lateral approach: A case report
Authors: Haocheng Cui, Zhengqi Chang, Xiuchun Yu
Journal: Front Surg (2022)
Keywords: brucella spondylitis, extreme lateral interbody fusion (xlif), negative pressure wound therapy (npwt), spinal infection, vacuum sealing drainage (vsd)
MeSH terms: Case Reports

Brucella spondylitis (BS) is a specific spinal infection. Surgical treatment is required for Brucella spondylitis that has caused neurological symptoms in the lower extremities and developed an intraspinal abscess. The main purpose of surgery is to remove the lesion and restore the stability of the spine. However, both the anterior approach and the posterior approach cannot completely remove the lesions, resulting in a low cure rate and a certain recurrence rate. Although anterior or posterior debridement is more thorough, it is unbearable for some patients with poor general condition. In this study, for the first time, a negative pressure wound therapy (NPWT) device was introduced into the intervertebral space through the extreme lateral approach to treat a patient with Brucella spondylitis. We summarize the treatment process, and discuss the feasibility and effectiveness of this surgical approach through 1-year follow-up.
Hypoglossal dural arteriovenous fistula: a rare cause of unilateral hypoglossal nerve palsy
Authors: Nathan Howard Ho Leung Chan
Journal: BJR Case Rep (2017)
MeSH terms: Case Reports

Ms Y, a 57-year-old female presented with a 1-week history of tongue deviation. The history of the presenting complaint also included minor dysarthria, dysphagia for solids and liquids as well as a 2- to 3-month history of pulsatile tinnitus affecting the right ear. Examination of the cranial and peripheral nerves revealed a right hypoglossal nerve lower motor neurone palsy. MRI demonstrated a dural arteriovenous fistula (DAVF) in the region of the right hypoglossal canal. She underwent a cerebral angiogram, which confirmed a hypoglossal DAVF with predominant supply from the neuromeningeal branches of the right ascending pharyngeal artery. She has been able to cope with her symptoms and remains on active surveillance. Hypoglossal nerve palsy is uncommon, causes may be classified according to location. DAVFs are a rare cause of hypoglossal nerve palsy. DAVFs can be graded according to their pattern of venous drainage. This case illustrates the complex venous anatomy of the craniocervical junction, which enables postural-dependent drainage through the internal jugular and vertebral venous systems. This network of veins is encountered during interventional radiology procedures and neurosurgical skull base approaches.
Endoscopic Resection of Pseudoarticulation as a Treatment for Bertolotti's Syndrome
Authors: Eric Stein, Geoffrey D Panjeton, Sanjeev Kumar
Journal: Cureus (2023)
Keywords: bertolotti's syndrome, chronic low back pain, endoscopic resection, endoscopic spine surgery, interventional pain management, lumbosacral transitional vertebrae, pseudoarticulation
MeSH terms: Case Reports

Bertolotti's syndrome is described as lower back pain with the presence of lumbosacral transitional vertebrae (LSTV) associated with an articulation, pseudoarticulation, or full fusion of the transverse process to the sacrum and ilium. We present a unique case of the management of a 57-year-old woman with treatment-resistant lower back pain who underwent endoscopic resection of a pseudoarticulation related to LSTV. The patient underwent multiple treatment regimens without achieving satisfactory relief. These included physical therapy, sacroiliac (SI) joint injections, radiofrequency lesioning at multiple levels, and spinal cord stimulator placement. Relief with injection at the patient's pseudoarticulation confirmed this as a contributor to the patient's back pain. Interventional management of Bertolotti's syndrome can include different modalities, most recently including minimally invasive surgical techniques. This patient experienced partial relief of lower back pain after undergoing minimally invasive resection of the pseudoarticulation. This case demonstrates the benefit of a minimally invasive resection of this anatomic abnormality in a patient who has undergone previous treatments. Isolating this anomaly as a source of pain is necessary to ensure a favorable response and prevent needless surgery.
Severe Restrictive Lung Disease in One of the Oldest Documented Males With Coffin-Lowry Syndrome
Authors: Frederick Venter, Andrew Evans, Claudia Fontes, Carol Stewart
Journal: J Investig Med High Impact Case Rep (2019)
Keywords: cobb’s angle, coffin-lowry, kyphoscoliosis, mental retardation, restrictive lung disease
MeSH terms: Coffin-Lowry Syndrome / complications, Lung Diseases / complications, Paraplegia / complications, Scoliosis / complications, Case Reports, Abnormalities, Multiple / genetics, Adult, Coffin-Lowry Syndrome / genetics, Humans, Lung Diseases / diagnostic imaging, Lung Diseases / genetics, Male, Paraplegia / genetics, Phenotype, Radiography, Thoracic, Ribosomal Protein S6 Kinases, 90-kDa / genetics, Scoliosis / diagnostic imaging, Scoliosis / genetics, Tomography, X-Ray Computed, Ribosomal Protein S6 Kinases, 90-kDa, ribosomal protein S6 kinase, 90kDa, polypeptide 3

Coffin-Lowry syndrome is expressed as different phenotypes in males and females. In males, it is characterized by facial abnormalities, marked developmental disability, and skeletal changes. Approximately 80% of cases are associated with kyphoscoliosis, which can be quite severe, as seen in our patient, causing paraplegia and restrictive lung disease. In this article, we present the third oldest documented male case of Coffin-Lowry syndrome with severe kyphoscoliosis, paraplegia, and restrictive lung disease.
Three trocars laparoscopic resection of angiomyolipoma of the liver
Authors: J M Ramia, R De la Plaza, J Quiñones, M D Sanchez-Tembleque, A Caminoa, P Veguillas, J García Parreño
Journal: Int J Hepatol (2011)
MeSH terms: Case Reports

Angiomyolipoma of the liver (AML) is an infrequent neoplasm composed of three tissues (adipose, muscle and vessels). In spite of advances in radiology, preoperative correct diagnosis is difficult. Clasically, a conservative management strategy was adopted in patients with asymptomatic tumors less than 5 cm with undoubtful diagnosis. But after publishing some few cases of malignant angiomyolipoma a more radical has been advocated. Laparoscopic resection of liver tumors is becoming a excellent approach for operating on benign liver tumors. Usually is performed using five trocars but in some cases a less invasive technique with three trocars could be used. We present a laparoscopic resection of liver angiomyolipoma in a 65 year-old male using only three trocars and also discuss the optimal management of AML and technical tips of three-trocar technique.
Phantom limb therapy improves cortical efficiency of the sensorimotor network in a targeted muscle reinnervation amputee: a case report
Authors: Jordan A Borrell, Arun Karumattu Manattu, Christopher Copeland, Kaitlin Fraser, Andrew D'Ovidio, Zach Granatowicz, Alex C Lesiak, Sean C Figy, Jorge M Zuniga
Journal: Front Neurosci (2023)
Keywords: amputation – rehabilitation, functional near infrared spectroscopy, hemodynamic responses, neural plasticity, phantom limb movements, targeted muscle reinnervation (tmr)
MeSH terms: Case Reports

Targeted muscle reinnervation (TMR) surgery involves the coaptation of amputated nerves to nearby motor nerve branches with the purpose of reclosing the neuromuscular loop in order to reduce phantom limb pain. The purpose of this case study was to create a phantom limb therapy protocol for an amputee after undergoing TMR surgery, where the four main nerves of his right arm were reinnervated into the chest muscles. The goal of this phantom limb therapy was to further strengthen these newly formed neuromuscular closed loops. The case participant (male, 21- years of age, height = 5'8″ and weight = 134 lbs) presented 1- year after a trans-humeral amputation of the right arm along with TMR surgery and participated in phantom limb therapy for 3 months. Data collections for the subject occurred every 2 weeks for 3 months. During the data collections, the subject performed various movements of the phantom and intact limb specific to each reinnervated nerve and a gross manual dexterity task (Box and Block Test) while measuring brain activity and recording qualitative feedback from the subject. The results demonstrated that phantom limb therapy produced significant changes of cortical activity, reduced fatigue, fluctuation in phantom pain, improved limb synchronization, increased sensory sensation, and decreased correlation strength between intra-hemispheric and inter-hemispheric channels. These results suggest an overall improved cortical efficiency of the sensorimotor network. These results add to the growing knowledge of cortical reorganization after TMR surgery, which is becoming more common to aid in the recovery after amputation. More importantly, the results of this study suggest that the phantom limb therapy may have accelerated the decoupling process, which provides direct clinical benefits to the patient such as reduced fatigue and improved limb synchronization.
Primary Leptomeningeal Oligodendroglioma, IDH-Mutant, 1p/19q-Codeleted
Authors: Leomar Y Ballester, Erin Dunbar, Nandita Guha-Thakurta, John W Henson, Howard Chandler, Jeremiah Watkins, Gregory N Fuller
Journal: Front Neurol (2018)
Keywords: 1p/19q-codeletion, atrx, cic, fubp1, idh1, diffuse glioma, leptomeningeal oligodendroglioma
MeSH terms: Case Reports

We present a case of a 43-year-old woman with a history of headaches and blurry vision. Ophthalmologic examination identified papilledema. MR imaging demonstrated a right parietal region mass with patchy areas of contrast enhancement and focal calcifications. Intraoperative examination and exploration revealed an extra-axial mass with no apparent parenchymal involvement. Microscopic examination revealed solid sheets of tumor cells with clear cell cytologic features and no discernable intra-parenchymal tumor component. Molecular studies demonstrated the presence of IDH1 IDH1 c.395G>A p.R132H and CIC c.601C>T p.R281W mutations and 1p/19q codeletion. The radiographic features, gross appearance, and microscopic and molecular characteristics of the mass support the diagnosis of primary leptomeningeal oligodendroglioma, IDH-mutant, 1p/19-codeleted. This case represents one of a very few reported instances of molecularly-defined solitary, primary, intracranial oligodendroglioma, without definitive involvement of the brain parenchyma.
Pulmonary carcinosarcoma initially presenting as invasive aspergillosis: a case report of previously unreported combination
Authors: Ariyo O Olobatoke, Doina David, Wasif Hafeez, Thien Van, Husain A Saleh
Journal: Diagn Pathol (2010)
MeSH terms: Carcinosarcoma / diagnosis, Invasive Pulmonary Aspergillosis / diagnosis, Lung Neoplasms / diagnosis, Case Reports, Aged, Antifungal Agents / therapeutic use, Aspergillus / isolation & purification, Biopsy, Fine-Needle, Carcinosarcoma / complications, Carcinosarcoma / surgery, Fatal Outcome, Humans, Invasive Pulmonary Aspergillosis / complications, Invasive Pulmonary Aspergillosis / drug therapy, Lung Neoplasms / complications, Lung Neoplasms / surgery, Male, Pneumonectomy, Pneumonia / microbiology, Thoracotomy, Tomography, X-Ray Computed, Treatment Outcome, Antifungal Agents

Carcinosarcoma of the lung is a malignant tumor composed of a mixture of carcinoma and sarcoma elements. The carcinomatous component is most commonly squamous followed by adenocarcinoma. The sarcomatous component commonly comprises the bulk of the tumor and shows poorly differentiated spindle cell features. Foci of differentiated sarcomatous elements such as chondrosarcoma and osteosarcoma may be seen. Aspergillus pneumonia is the most common form of invasive aspergillosis and occurs mainly in patients with malignancy, immunocompromising or debilitating diseases. Patients with Aspergillus pneumonia present with fever, cough, chest pain and occasionally hemoptysis. Tissue examination is the most reliable method for diagnosis, and mortality rate is high.We describe a case of primary carcinosarcoma of the lung concurrently occurring with invasive pulmonary aspergillosis in a 66-year old patient.
An unusual case of pulmonary granulocytic sarcoma treated with combined chemotherapy and radiation
Authors: Vishwanath Sathyanarayanan, Nagesh Taterao Sirsath, Umesh Das, M Malathi, Suma Lakshmipathi Reddy, Kavitha S Srivatsa, Avinash Thumallapalli, L Appaji, Bs Aruna Kumari
Journal: Ecancermedicalscience (2013)
Keywords: chemotherapy, granulocytic sarcoma, pulmonary, radiation
MeSH terms: Case Reports

We report an unusual case of a 6-year-old male child who presented with fever and a cough of one month's duration. A bone marrow aspiration and cytogenetics were suggestive of acute myeloid leukaemia with t(8;21)(q22;q22). A chest x-ray and computed tomography of the thorax showed a soft tissue lesion in the right lung. The fine needle aspiration cytology (FNAC) of this lesion was suggestive of pulmonary granulocytic sarcoma. The patient was successfully treated with induction chemotherapy (cytosine arabinoside + daunomycin), followed by consolidation with high-dose cytosine arabinoside. In view of the persistent lesion in the right lung, the patient was given external beam radiotherapy (EBRT), which resulted in near total resolution of the lung granulocytic sarcoma. We report this case in view of its rarity and clinical importance, and to highlight the treatment options in this scenario.
Successful continuous-flow left ventricular assist device implantation with adjuvant tricuspid valve repair for advanced heart failure
Authors: Chih-Hsien Lee, Jeng Wei
Journal: Cardiovasc J Afr (2016)
MeSH terms: Cardiac Valve Annuloplasty, Heart Failure / therapy, Heart-Assist Devices, Tricuspid Valve / surgery, Ventricular Function, Left, Case Reports, Adult, Heart Failure / diagnosis, Heart Failure / physiopathology, Heart Failure / surgery, Hemodynamics, Humans, Male, Prosthesis Design, Recovery of Function, Time Factors, Treatment Outcome, Tricuspid Valve / physiopathology

The prevalence of end-stage heart failure (HF) is on the increase, however, the availability of donor hearts remains limited. Left ventricular assist devices (LVADs) are increasingly being used for treating patients with end-stage HF. LVADs are not only used as a bridge to transplantation but also as a destination therapy. HeartMate II, a new-generation, continuous-flow LVAD (cf-LVAD), is currently an established treatment option for patients with HF. Technological progress and increasing implantation of cf-LVADs have significantly improved survival in patients with end-stage HF. Here we report a case of a patient with end-stage HF who was successfully supported using cf-LVAD implantation with adjuvant tricuspid valve repair in a general district hospital.
Mycobacterium tuberculosis and Dual M. tuberculosis/ M. bovis Infection as the Cause of Tuberculosis in a Gorilla and a Lioness, Respectively, in Ibadan Zoo, Nigeria
Authors: Aina Adeogun, Olutayo Omobowale, Chiaka Owuamanam, Olugbenga Alaka, Victor Taiwo, Dick van Soolingen, Simeon Cadmus
Journal: Case Rep Vet Med (2016)
MeSH terms: Case Reports

Tuberculosis (TB) in zoo animals is an important public health problem in places where it occurs. This is even very important in countries where there is little public health awareness about the disease; thus confined animals in the zoo can be infected directly or indirectly by infected humans and vice versa. In Nigeria, the problem of TB is a major concern among both humans and cattle. Here, we present cases of Mycobacterium tuberculosis and M. tuberculosis/M. bovis infections in a female gorilla and a lioness, respectively, in a zoo in Ibadan, Nigeria. These cases were confirmed after bacteriological examinations and DNA from granulomatous lesions of the animals' carcasses were subjected to the Hain and spoligotyping techniques. Our findings reveal the first documented report of TB infections in a gorilla and a lioness in zoo animals in Nigeria. The public health risks of tuberculosis in zoological settings are therefore reemphasized.
Usage of a rotational flap for coverage of a large central forehead defect
Authors: Ahmed Hassan El-Sabbagh
Journal: GMS Interdiscip Plast Reconstr Surg DGPW (2017)
Keywords: central area, forehead, large defect, rotation flap
MeSH terms: Case Reports

Background: The forehead is a donor site for facial reconstruction but has no generous donor site for its coverage. All options of the reconstructive ladder can be used. A large rotation flap was used to reconstruct a big central forehead defect following failed previous repair in an elderly diabetic patient after a motor car accident. Case presentation: A 64-year-old diabetic man presented with an extensive central forehead defect after failed previous repair following a motor car accident. Coverage of the defect was performed using a flap based around the ear on one side in a rotation movement. An accepted functional and esthetic result was achieved after 3 months of follow-up. Conclusion: A rotation flap based on arteries around the ear can be used for coverage of a difficult lesion in the central forehead. Level of evidence: Level V, therapeutic study.
Capnocytophaga canimorsus as Cause of Fatal Sepsis
Authors: Moritz Hundertmark, Tatjana Williams, Anja Vogel, Maria Moritz, Peter Bramlage, Nikolaos Pagonas, Oliver Ritter, Benjamin Sasko
Journal: Case Rep Infect Dis (2019)
MeSH terms: Case Reports

A rare consequence of dog bites is the infection with Capnocytophaga canimorsus, and only a few cases have been documented. We describe a 41-year-old, formerly healthy woman who died from septic shock and multiorgan failure. It is the first case of a young individual without obvious immunosuppression.
Hepatic Sclerosing Hemangioma with Predominance of the Sclerosed Area Mimicking a Biliary Cystadenocarcinoma
Authors: Hiroyuki Sugo, Yuki Sekine, Shozo Miyano, Ikuo Watanobe, Michio Machida, Kuniaki Kojima, Hironao Okubo, Ayako Ura, Kanako Ogura, Toshiharu Matsumoto
Journal: Case Reports Hepatol (2018)
MeSH terms: Case Reports

We report here an extremely rare case of hepatic sclerosing hemangioma mimicking a biliary cystadenocarcinoma. A previously healthy 39-year-old woman was referred to our hospital because of a large tumor in the liver. Abdominal computed tomography revealed early peripheral ring enhancement in the arterial phase and slight internal heterogeneous enhancement in the delayed phase. Magnetic resonance imaging revealed a tumor with low intensity in the T1-weighted image and very high intensity in the fat-saturated T2-weighted image. The patient underwent hepatectomy for a possible malignant liver tumor. Grossly, the tumor appeared as a white, solid, and cystic mass (weighted 1.1 kg and measured 170×100×80 mm) that was elastic, soft, and homogeneous with a yellowish area. Histological examination showed that the tumor mostly consisted of fibrotic areas with hyalinization. The typical histology of cavernous hemangioma was confirmed in part, and the tumor was diagnosed as a sclerosing hemangioma with predominancy of the sclerosed area. A review of 20 cases reported previously revealed that only 2 (10%) patients were diagnosed as having sclerosing hemangioma preoperatively.
Mini-percutaneous nephrolithotomy via ultrasound guidance in transplanted kidney: a report of two cases
Authors: Ali Eslahi, Mehdi Salehipour, Mohammad Mehdi Hosseini, Faisal Ahmed, Seyed Hossein Hosseini, Sajad Ghafari
Journal: Pan Afr Med J (2022)
Keywords: percutaneous nephrolithotomy, case report, endourology, kidney transplant, urolithiasis
MeSH terms: Kidney Calculi / diagnostic imaging, Kidney Calculi / surgery, Nephrolithotomy, Percutaneous, Nephrostomy, Percutaneous / methods, Case Reports, Adult, Female, Humans, Kidney, Male, Treatment Outcome, Ultrasonography, Young Adult

Urolithiasis is a rare but familiar problem in transplanted kidney patients, with a prevalence rate between 0.23-6.3%. Minimally invasive percutaneous nephrolithotomy (mini-PCNL) is a revised technique that uses a miniature endoscope through a small access sheath and is associated with minor bleeding risk. Only a few cases of mini-PCNL via ultrasonography (US) guidance in transplanted kidneys have been published. We present a 23-year-old female and a 34-year-old man who presented with obstructive uropathy due to impacted stones in their transplanted kidneys. Firstly, the nephrostomy tube was inserted. Then, they underwent mini-PCNL via US guidance. Puncturing the pyelocaliceal system was achieved via a 3.5 MHz US probe. Procedures were performed with a one-shot dilatation technique and a 15-Fr rigid nephroscope. In conclusion, we suggest that if an experienced urologist performs it, the US-guided mini-PCNL is safe and effective in patients with transplanted kidneys.
Use of fibrin glue in periodontal flap surgery
Authors: Bimal Jathal, Anal Trivedi, Neeta Bhavsar
Journal: J Indian Soc Periodontol (2008)
Keywords: fibrin glue, periodontal flap closure, sutureless periodontal surgery
MeSH terms: Case Reports

In the changing era of perio surgeries one innovative remedy has ended the inconvenience of suturing and has allowed the clinician to meet growing expectations and demands of today's dental patient, and the remedy is fibrin glue. When periodontal plastic surgical procedures done or implants placed in esthetic zone, fibrin sealants may be variable alternative to closing flaps with sutures and with histologic benefits and has potential uses in field of medicine. Fibrin sealant is an excellent beginner in the era of sutureless periodontal flap surgery, and this article is a humble effort to prove it.
Ceftriaxone-induced cholestatic hepatitis in a child: A case report and a review of the literature
Authors: Massimo Luca Castellazzi, Carlo Virginio Agostoni, Jessica Palella, Daniela Civeriati, Paola Marchisio, Gabriella Nebbia
Journal: Front Pediatr (2022)
Keywords: antibiotic, ceftriaxone, children, cholestasis, hepatitis
MeSH terms: Case Reports

Ceftriaxone, a third-generation cephalosporin, is commonly used in pediatric patients and is generally well tolerated. Its more frequent adverse effects are biliary pseudolithiasis, urolithiasis, and hemolytic anemia. On the other hand, ceftriaxone-induced acute cholestatic hepatitis is a very rare condition, especially in children. Here, we describe a case of this condition in a young male child to highlight the importance of suspecting this drug-induced liver injury to achieve a prompt diagnosis.
Endometrial carcinoma located in the right septate uterus cavity: a case report
Authors: Ikram Boubess, Youssef Mahdi, Hanan Ramsiss, Adib Filali, Mohamad Hassan Alami, Basma El Khannoussi, Hafid Hachi
Journal: Pan Afr Med J (2015)
Keywords: endometrial cancer, septate uterus, uterine malformation
MeSH terms: Endometrial Neoplasms / diagnosis, Urogenital Abnormalities / pathology, Uterus / abnormalities, Case Reports, Aged, Endometrial Neoplasms / pathology, Female, Humans, Uterus / pathology, Uterine Anomalies

Endometrial cancer in patients with uterine congenital malformations is exceptional and there are only a few rare cases published in the literature. We report the case of a 67 years-old patient with an endometrial cancer located in the right cavity of a complete septate uterus.