OpenMed/multicare-articles huggingface dataset:
Abdominopelvic Tuberculosis Secondary to a Nontuberculous Mycobacterium in an Immunocompetent Patient
Authors: Beng Kwang Ng, Kembang Aziah Yakob, Wendy Yin Ling Ng, Pei Shan Lim, Rahana Abd Rahman, Abdul Kadir Abdul Karim, Ani Amelia Zainuddin, Zaleha Abdullah Mahdy
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

Tuberculosis (TB) remained as one of the top 10 causes of death worldwide despite an overall decline in its incidence rate globally. Extrapulmonary TB is uncommon and only accounts for 10-20% of overall TB disease burden. Abdominopelvic TB is the sixth most common location of extrapulmonary TB. The symptoms and signs are often insidious and nonspecific. Diagnosing abdominopelvic TB can be very challenging at times and poses great difficulties to the clinician. Infection with nontuberculous Mycobacterium (NTM) is even rarer especially in an immunocompetent patient. We report a case of NTM in abdominopelvic TB. A 37-year-old foreign worker, para 3, presented with a one-week history of suprapubic pain associated with fever. An assessment showed presence of a right adnexal mass. She was treated as tuboovarian abscess with intravenous antibiotics. Unfortunately, she did not respond. She underwent exploratory laparotomy. Intraoperatively, features of the mass were suggestive of a right mature cystic teratoma with presence of slough and cheesy materials all over the abdominal cavity as well as presence of ascites. Diagnosis of NTM was confirmed with PCR testing using the peritoneal fluid. This case was a diagnostic dilemma due to the nonspecific clinical presentation. Management of such rare infection was revisited.
Imaging, Histopathologic, and Treatment Nuances of Pulmonary Carcinosarcoma
Authors: Tyler Gleason, Michael Haas, Brian H Le
Journal: Case Rep Radiol (2017)
MeSH terms: Case Reports

A 76-year-old female with coronary artery disease, chronic obstructive pulmonary disease, diabetes mellitus type II, and 40 pack-year smoking history presented with a four-day history of cough, productive of green-yellow sputum. Chest X-ray revealed opacification of the left upper lung field, and computed tomography (CT) of the chest showed a large cavitary lesion invading the T2-T3 vertebral bodies, extending into the epidural space, giving rise to mild cord compression. Biopsy of the lesion revealed a poorly differentiated neoplasm composed of distinct epithelial and mesenchymal components, consistent with carcinosarcoma. A metastatic workup was negative. Primary lung carcinosarcoma is a rare tumour that can demonstrate an especially aggressive clinical course; diagnosis is often nuanced by limited sampling at initial presentation, especially in a setting of advanced disease and debility that precludes consideration for upfront resection or more extensive, invasive sampling.
Case report: Tissue positivity for SARS-CoV-2 in a preterm born infant death of thrombosis: possible intrauterine transmission
Authors: Salvatore Greco, Juana Maria Sanz, Daria Bortolotti, Chiara Marina Semprini, Carlotta Braga, Roberta Gafà, Erica Santi, Iva Maestri, Roberta Rizzo, Pantaleo Greco, Angelina Passaro
Journal: Front Med (Lausanne) (2023)
Keywords: sars-cov-2, gastrointestinal tract, intrauterine transmission, newborn, placenta, pulmonary embolism, thrombosis
MeSH terms: Case Reports

Intrauterine transmission of SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) is still matter of debate among scientists and there is limited information concerning this aspect of research. This could lead to severe complications of the growing fetus and, theoretically, of the newborn as well. We report the case of a male infant of 1,100 grams, born at 27th week of gestation to a SARS-CoV-2 mother, tested negative for viral detection at delivery. He was immediately admitted to neonatal Intensive Care Unit (ICU) for severe complications, where he died after 37 days by pulmonary embolism and thrombosis of the superior vena cava. After autopsy, SARS-CoV-2 N-protein and Spike RBD were detected in several tissues, particularly in the esophagus, stomach, spleen, and heart, with a significantly higher H-Score than the placenta. In conclusion, immunohistochemical analysis demonstrated SARS-CoV-2 NP and Spike RBD positivity in different tissues suggesting a possible intrauterine transmission. Newborn thrombo-embolism could be a complication of SARS-CoV-2 infection as observed in adult patients.
Symptomatic Aortic Paravalvular Leak: Percutaneous Treatment with Amplatzer Vascular Plug III Device as an Alternative to Surgery
Authors: Gabriel E Pérez Baztarrica, Gastón Heredia, Juan Arellano, Juan Fernández, Rafael Porcile
Journal: Braz J Cardiovasc Surg (2018)
MeSH terms: Bioprosthesis / adverse effects, Embolization, Therapeutic / instrumentation, Heart Failure / therapy, Heart Valve Prosthesis / adverse effects, Septal Occluder Device, Case Reports, Aged, 80 and over, Echocardiography, Transesophageal, Heart Failure / diagnosis, Heart Failure / etiology, Humans, Male

A significant prosthetic paravalvular leak is an uncommon and severe postsurgical complication correlated to the occurrence of congestive heart failure and hemolytic anemia. Percutaneous treatment has become an attractive and effective proposal to relieve symptoms and reduce complications in patients whose high rate of morbidity/mortality precludes a new surgery. This is the case of an 81-year-old patient with a history of biological aortic valve replacement seeking medical help due to heart failure and hemolytic anemia, with a prosthetic paravalvular regurgitation jet and high surgical mortality according to EuroSCORE II.
"Being with a Buddha": A Case Report of Methoxetamine Use in a United States Veteran with PTSD
Authors: Joan M Striebel, Emily E Nelson, Raj K Kalapatapu
Journal: Case Rep Psychiatry (2017)
MeSH terms: Case Reports

Methoxetamine (MXE) is a ketamine analogue with a high affinity for the N-methyl-D-aspartate (NMDA) receptor. MXE is a newly emerging designer drug of abuse and is widely available through on-line sources and is not detected by routine urine drug screens. In this report, we describe a United States (US) veteran with posttraumatic stress disorder (PTSD) and heavy polysubstance use, who injected high dose MXE for its calming effect. Given MXE's structural similarities to ketamine and recent work showing that ketamine reduces PTSD symptoms, we hypothesize that MXE alleviated this veteran's PTSD symptoms through action at the NMDA receptor and via influences on brain-derived neurotrophic factor (BDNF). To our knowledge, this is the first case report of self-reported use of MXE in the US veteran population. More awareness of designer drugs, such as MXE, is an important first step in engaging patients in the treatment of designer drug addiction in both military/veteran settings and civilian settings.
Laparoscopic Dismembered Pyeloplasty in a Solitary Kidney with Intrarenal Pelvis: Two Challenges in One Case
Authors: Akin Soner Amasyali, Erhan Ates, Hakan Görkem Kazici, Alper Nesip Manav, Haluk Erol
Journal: Case Rep Urol (2017)
MeSH terms: Case Reports

Laparoscopic pyeloplasty (LP) for ureteropelvic junction obstruction (UPJO) is one of the most appropriate surgical techniques to achieve the optimal goal of minimally invasive surgery. However, urologists hesitate to use the laparoscopic approach in UPJO with solitary kidney or intrarenal pelvis. There are a few published studies on laparoscopic pyeloplasty cases in intrarenal pelvis. However, to the best of our knowledge, the present case is the first in the literature in terms of intrarenal pelvis in a solitary kidney. Generally, YV plasty is the accepted technique instead of dismembered pyeloplasty in UPJO with small or intrarenal pelvis. However, in this report, we showed that dismembered LP can be performed with good results in intrarenal pelvis UPJO, even if it is in the solitary kidney.
Myocarditis Caused by Brucella melitensis in the Absence of Endocarditis: Case Report and Review of the Literature
Authors: Maria Lagadinou, Virginia Mplani, Dimitrios Velissaris, Periklis Davlouros, Markos Marangos
Journal: Case Rep Med (2019)
MeSH terms: Case Reports

Brucellosis remains an important public health problem with endemic characteristics in many countries. Brucellosis can affect almost all organs and systems of human body. Cardiac complications are unusual, occurring in less than 2% of patients and usually manifest as endocarditis. We present the case of a 21-year-old Caucasian man, who was admitted to the University Hospital of Patras, Western Greece, with fatigue, fever up to 39°C, and retrosternal pain. Musculoskeletal, genitourinary, gastrointestinal, hematologic, nervous, skin, and mucous membranes and respiratory complications have been reported in several cases of brucellosis. Development of myocarditis is a highly rare complication of brucellosis, particularly in the absence of concomitant endocarditis. Clinicians should be aware of this clinical entity especially in endemic areas as appropriate antibiotic treatment is life-saving and may prevent serious cardiologic disorders.
Adult-Onset ANCA-Associated Vasculitis in SAVI: Extension of the Phenotypic Spectrum, Case Report and Review of the Literature
Authors: Frederik Staels, Albrecht Betrains, Peter Doubel, Mathijs Willemsen, Vincent Cleemput, Steven Vanderschueren, Anniek Corveleyn, Isabelle Meyts, Ben Sprangers, Yanick J Crow, Stephanie Humblet-Baron, Adrian Liston, Rik Schrijvers
Journal: Front Immunol (2020)
Keywords: savi, glomerulonephritis, interferonopathy, primary immunodeficiency, vasculopathy
MeSH terms: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / genetics, Membrane Proteins / genetics, Mutation, Vascular Diseases / genetics, Case Reports, Research Support, Non-U.S. Gov't, Review, Age of Onset, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / diagnosis, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / immunology, Genetic Predisposition to Disease, Heredity, Heterozygote, Humans, Male, Pedigree, Phenotype, Prognosis, Vascular Diseases / diagnosis, Vascular Diseases / immunology, Young Adult, Membrane Proteins, STING1 protein, human

STING-associated vasculopathy with onset in infancy (SAVI) is an autosomal dominant disorder due to gain-of-function mutations in STING1, also known as TMEM173, encoding for STING. It was reported as a vasculopathy of infancy. However, since its description a wider spectrum of associated manifestations and disease-onset has been observed. We report a kindred with a heterozygous STING mutation (p.V155M) in which the 19-year-old proband suffered from isolated adult-onset ANCA-associated vasculitis. His father suffered from childhood-onset pulmonary fibrosis and renal failure attributed to ANCA-associated vasculitis, and died at the age of 30 years due to respiratory failure. In addition, an overview of the phenotypic spectrum of SAVI is provided highlighting (a) a high phenotypic variability with in some cases isolated manifestations, (b) the potential of adult-onset disease, and (c) a novel manifestation with ANCA-associated vasculitis.
Comparison of Sexual Dysfunction Using the Female Sexual Function Index following Surgical Treatments for Uterine Fibroids
Authors: Allison Ryann Louie, Jennifer Alice Armstrong, Laura Katherine Findeiss, Scott Craig Goodwin
Journal: Case Rep Obstet Gynecol (2012)

Uterine fibroids are a common problem in women. Statistics showing 20-50% of fibroids produce symptoms and consequently patients seek surgical intervention to improve their quality of life. Treatments for fibroids are typically successful in controlling the fibroid disease, yet sexual function following invasive surgical treatments for fibroids can be jeopardized. The Sexual Function Index (FSFI) is a valid instrument producing quantifiable reproducible results. In this paper three case reports are evaluated by the FSFI and compared between the following treatment groups: hysterectomy, myomectomy, and uterine embolization. Our goal is to illustrate how each of these treatment outcomes can result in sexual dysfunction and therefore decreased quality of life. Effects of invasive fibroid treatments on sexual functioning would be helpful in guiding patient's ultimate decisions regarding treatment.
Cryptogenic hepatitis simulating cyst rupture and hydatid jaundice in a patient with preexisting asymptomatic hydatid cyst
Authors: Ulas Aday, Cuneyt Kayaalp, Murat Kapan
Journal: Caspian J Intern Med (2017)
Keywords: cryptogenic hepatitis, hydatid liver disease, jaundice, surgery
MeSH terms: Case Reports

Background:
Rupture into the biliary ducts is the most frequent complication of hydatid liver disease. In endemic areas of Echinococcus granulosus, development of jaundice in a patient with liver cyst is initially suspected to have hydatid cyst.
Case presentation:
A 48 year-old woman with history of asymptomatic hydatid liver cysts was admitted to the emergency department with right upper quadrant abdominal pain, increased levels of liver enzymes, bilirubin and alkaline phosphatase and the initial clinical diagnosis was the hydatid cyst rupture into the bile ducts. Surgery was planned but radiological evaluation (MRI) revealed non-dilated intra-extra biliary ducts. High suspicion of hydatid rupture required diagnostic ERCP that was normal and surgery was cancelled then. A possible diagnosis of coexistent hepatitis was suspected. Liver function tests normalized gradually and no cyst rupture was determined during surgery.
Conclusion:
These findings suggest considering the possible development of cryptogenic hepatitis in patients with preexisting hydatid cyst.
Tardive dystonia improved with discontinuation of trazodone in an elderly schizophrenia patient: a case report
Authors: Yoshinori Kadota, Hikaru Hori, Michiko Takayama, Chikako Okabe, Naotoshi Ohara
Journal: Ann Gen Psychiatry (2020)
Keywords: delirium, insomnia, schizophrenia, tardive dystonia, trazodone
MeSH terms: Case Reports

Background:
Tardive dystonia associated with antidepressant use is rare and often under-recognized. We had an experience with trazodone, which is used for delirium and insomnia prescribed in general hospital, inducing tardive dystonia.
Case presentation:
A 61-year-old Japanese woman had been treated for schizophrenia. She was moved to general hospital because of consciousness disturbance. She was prescribed trazodone (25 mg/day) for delirium and insomnia. After she was discharged, she returned to the psychiatric hospital with tardive dystonia. Her dystonia symptoms improved with 3 days of discontinuing trazodone.
Conclusion:
In the present case, long-term use of trazodone induced tardive dystonia. Discontinuing trazodone rapidly improved tardive dystonia.
Laparoscopic splenectomy for solitary splenic metastasis in patients with previous open surgery-Case series
Authors: Dobromir Dimitrov Dimitrov
Journal: Int J Surg Case Rep (2019)
Keywords: case report, case series, laparoscopic splenectomy, spleen metastasis

Introduction:
Solitary splenic metastases are a rare entity.
Presentation of a case:
We report two consecutive cases of solitary splenic metastases from ovarian and rectal cancer which were completely removed by laparoscopic splenectomy in patients with previous open surgery. The operative time was 165-200 min. The blood loss was 25-100 ml. There were no intra- and postoperative complications.
Conclusion:
Laparoscopic splenectomy for solitary splenic metastases seems safe and feasible with short recovery period even in patients with previous open surgery. More research in the area is needed.
Development of Tinnitus at a Low Dose of Sertraline: Clinical Course and Proposed Mechanisms
Authors: Christopher W T Miller
Journal: Case Rep Psychiatry (2016)

Introduction. Serotonin is involved in filtering of auditory stimuli. Cochlear input is processed through complex interactions between serotonergic, glutamatergic, and GABAergic neurotransmitter systems. Options for treatment of tinnitus include selective serotonin reuptake inhibitors (SSRIs); however in rare instances this symptom may occur as a side effect of this class of medications. Case Presentation. A 50-year-old woman developed bilateral tinnitus after several weeks of being treated with sertraline 50 mg. She had been on a long-standing daily dose of aspirin 325 mg which had been discontinued shortly before starting sertraline. Medical work-up was negative for her symptom. Shortly after discontinuation of the medication, her tinnitus subsided completely. Discussion. Tinnitus is a rare side effect of sertraline and may be related to particular distribution of serotonin receptor subtypes within the auditory system, and serotonergic agents may reinforce or desensitize the activity of different receptors. Also, there may be a priming effect of salicylate agents on the auditory system, predisposing particular patients to be more sensitive to how auditory stimuli are processed.
Dialogic Feminist Gathering and the Prevention of Gender Violence in Girls With Intellectual Disabilities
Authors: Roseli Rodrigues de Mello, Marta Soler-Gallart, Fabiana Marini Braga, Laura Natividad-Sancho
Journal: Front Psychol (2021)
Keywords: adolescents, dialogic environment, dialogic feminist gatherings, gender-based violence, intellectual disability, prevention, youth

Adolescent gender-based violence prevention and sexuality education is a topic of current concern given the increasing numbers of violence directed at girls. International organizations indicate that one in three girls aged 15 to 19 have experienced gender-based violence in their sexual relationships that this risk may be as much as 3-4 times higher for girls with disabilities. Following the good results obtained in the research project "Free_Teen_Desire" led by the University of Cambridge and funded by the Marie Curie Actions Program in the prevention of gender violence in adolescents through Dialogic Feminist Gatherings (DFG), the aim of study is to analyze Its transfer and impact on adolescent girls with intellectual disabilities. The DFGs are here understood as generators of a more dialogic environment for girls in general and we wonder if and how It is extended to the context of girls with disabilities. Thus, the research takes the form of a case study with a communicative approach on a DFGs. The intervention is carried out in a special school located in Valencia during the 2018-2019 and 2019-2020 academic years with a group of 19 non-mixed female students, female teachers, and the mother of one of the students. The study analyzes which are the transfer criteria to incorporate the DFGs in a special education context and what is their impact on the prevention of gender violence in girls with disabilities. The data collection techniques consist of two in-depth interviews, analysis of the field diary of 24 intervention sessions and a focus group with seven teachers. It is demonstrated that DFGs are successfully transferred to the special education context of the case study. The results show how contexts of safety, solidarity and friendship are generated which protect adolescent girls with disabilities from relationships with gender violence.
Myths and realities in the management of the open abdomen with negative pressure systems. A case report and literature review
Authors: J Aguilar-Frasco, P Moctezuma-Velázquez, J H Rodríguez-Quintero, F U Pastor-Sifuentes, E Sanchez Garcia-Ramos, U Clemente-Gutierrez, J Morales-Maza, O Santes, J D Hernández-Acevedo, E Contreras-Jimenez, S Mier Y Terán
Journal: Int J Surg Case Rep (2019)
Keywords: abdominal sepsis, negative pressure therapy, open abdomen, vac therapy

Introduction:
The open abdomen is a useful resource for treating patients with abdominal hypertension and abdominal compartment syndrome. Currently, early closure assisted with negative pressure devices is considered standard of treatment, and its use has demonstrated favorable outcomes and a decreased rate of complications.
Presentation of a case:
We present a case of a 32-year-old male patient with diagnosis of non-seminomatous germinal testicular tumor (Stage IIIB (T3-N3-M1), which was summited to surgery, as a complication he presented massive bleeding, that culminated in acute compartment syndrome. With the aforementioned findings the patient re entered the operating room and was managed with open abdomen combined with a medial retraction technique of the abdominal fascia. Currently, the patient has not presented recurrence or late complications after a year.
Discussion:
The use of negative pressure techniques for open abdomen management began to be generalized in 1995. Subsequently, this technique evolved to V.A.C therapy (Vacuum-assisted closure therapy). Currently, these negative pressure techniques have become the most used method for the temporary closure and management of open abdomen. Controversies continue to limit its widespread use and effectiveness.
Conclusion:
Adequate application of negative pressure therapy in combination with techniques of medial retraction of the abdominal fascia, have proved to be useful in management for patients with open abdomen.
COVID-19-Related Intracerebral Hemorrhage
Authors: Valentin Pavlov, Ozal Beylerli, Ilgiz Gareev, Luis Fernando Torres Solis, Arturo Solís Herrera, Gjumrakch Aliev
Journal: Front Aging Neurosci (2020)
Keywords: covid-19, complications, intracerebral hemorrhage, neurological consequences, pathophysiological mechanisms
MeSH terms: Case Reports

Intracerebral hemorrhage (ICH) is a common and severe neurological disorder and is associated with high rates of mortality and morbidity. ICH is associated with old age and underlying conditions such as hypertension and diabetes mellitus. The COVID-19 pandemic is associated with neurological symptoms and complications including ICH. For instance, the mechanisms by which COVID-19 may contribute to hemorrhagic stroke may include both depletion of angiotensin converting enzyme 2 (ACE2) receptor and overactive immune response. In this study, we herein report three patients (0.25%) out of 1200 admissions with COVID-19 to our center between 1 May and August 4, 2020, who developed ICH. In addition, we will briefly discuss the possible pathophysiological mechanisms of COVID-19 infection in patients with ICH.
Thymoma with coexisting undifferentiated pleomorphic sarcoma: a case report
Authors: Manoranjan Varshney, Mohammad Shahid, Veena Maheshwari, Aysha Mubeen, Mohammed Azfar Siddiqui
Journal: Case Rep Pulmonol (2011)
MeSH terms: Case Reports

We report here a case of thymoma simultaneously associated with undifferentiated pleomorphic sarcoma. A 45-year-old male presented with axillary lump. Radiographic studies showed a mediastinal mass. On fine needle aspiration cytology and histopathological examination, a diagnosis of thymoma with coexisting undifferentiated pleomorphic sarcoma was made. Although thymomas are associated with many extrathymic malignancies, it's association with undifferentiated pleomorphic sarcoma is rare. This case is being reported on to reinforce that clinicians should bear in mind the possibility of extrathymic malignancies in patients with thymomas.