OpenMed/multicare-articles huggingface dataset:
Peripheral ossifying fibroma
Authors: Meenakshi Bhasin, Vinny Bhasin, Abhilasha Bhasin
Journal: Case Rep Dent (2013)

Intraoral ossifying fibromas have been described in the literature since the late 1940s. Peripheral ossifying fibroma (POF) is usually a fibroma of the gingival which shows areas of calcification or ossification. It is a nonneoplastic enlargement of gingiva. Due to its clinical and histopathological similarities, some POFs are believed to develop initially as a pyogenic granuloma that undergoes fibrous maturation and subsequent calcification. It has been suggested that POF represents a separate clinical entity rather than a transitional form of pyogenic granuloma or irritation fibroma. This paper describes a case report of a 60-year-old female patient reported with growth on gingiva in the upper left front region of mouth three years ago.
Erythroderma and Skin Desquamation in Paederus Dermatitis
Authors: Thitinan Kitisin, Passanesh Sukphopetch
Journal: Case Rep Med (2021)
MeSH terms: Case Reports

Exfoliative erythroderma is rare but serious condition, which requires close supervision. We report a rare case of 28-year-old man with kissing lesions of Paederus dermatitis at his right side of neck. The rash caused by Paederus beetle was improved after treatments. However, the patient developed generalized erythema with desquamation and scaling. The patient was successfully treated topically with moisturizing liquid soap and topical moisturizer with emollients and humectants, and triamcinolone lotion was applied on the bright red lesion. The patient was also treated with oral replacement solution and tropical azelaic cream was applied on the hyperpigmented kissing lesion. This case report shows the importance of a diagnostic practice with follow-up examination.
A case of obstructive sleep apnea and assessments of fitness for work
Authors: Sukwoo Hong, Yewon Kim, Ji-Young Ryu, Sangyoon Lee, Byung-Chul Son, Chae-Kwan Lee, Dae-Hwan Kim
Journal: Ann Occup Environ Med (2014)
Keywords: fitness for work, obstructive sleep apnea, polysomnography
MeSH terms: Case Reports

Background:
Obstructive sleep apnea is a common sleep disorder that can cause excessive daytime sleepiness and impairment of cognition. These symptoms may lead to the occurrence of occupational accidents in workers with obstructive sleep apnea.
Case presentation:
A 36-year-old man who worked as a dimensional control surveyor caused a vehicle accident while he was driving at the work site. Although he experienced loss of consciousness at the time of the accident, he had no other symptoms. His brain computed tomography and laboratory test did not show any specific findings. Medical tests were conducted to evaluate his fitness for work. Decreased sleep latency was observed on the electroencephalography image, which is suggestive of a sleep disorder. He frequently experienced daytime sleepiness and his Epworth sleepiness score was 13. The polysomnography showed a markedly increased apnea-hypopnea index of 84.3, which led to a diagnosis of severe obstructive sleep apnea. The patient was advised to return to work only when his obstructive sleep apnea improved through proper treatment.
Conclusion:
Proper screening for obstructive sleep apnea among workers is important for preventing workplace accidents caused by this disorder, but screening guidelines have not yet been established in Korea. An effort toward preparing practical guidelines for obstructive sleep apnea is needed.
Multiple Bony Injuries on Bone Scan in a Case of Unsuspected Child Abuse
Authors: Ya-Wen Chuang, Chien-Chin Hsu, Chin-Chuan Chang, Chia-Yang Lin, Hsiu-Lan Chu, Ying-Fong Huang, Yu-Chang Tyan
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

This case is described of an eleven-month-old infant with lower limbs swelling and the left elbow skeletal malformation following a fall. The radionuclide bone scan was performed to exclude bone infection or congenital skeletal anomaly. The images unexpectedly showed multiple increased radioactive foci throughout the whole body. It was a strong probability of child abuse. All lesions are readily apparent on the following plain film radiographs and MRI.
Case Report: Successful Intravenous Lipid Emulsion Therapy for Canine Amphetamine Toxicosis
Authors: Stephanie Harris, Maureen A McMichael, Roy Harmon, Dawn Boothe
Journal: Front Vet Sci (2022)
Keywords: adderall xrⓡ, dog, intralipid, methamphetamine, overdose, poisoning
MeSH terms: Case Reports

A 4-year-old, female-spayed, mixed breed dog, weighing 24.2 kg, was presented for acute ingestion of ~12.3 mg/kg of Adderall XRⓇ, an extended-release amphetamine medication. In dogs, the oral median lethal dose for amphetamines ranges anywhere from 9-11 mg/kg to 20-27 mg/kg. On presentation, the patient was agitated, tachycardic and hypertensive. Initial treatment was instituted with intravenous lipid emulsion (IVLE) therapy, and baseline and post-treatment amphetamine concentrations were quantified in serum and plasma. In both serum and plasma, post-IVLE concentrations of amphetamine were lower 1 h after treatment and IVLE was the only treatment instituted during this time. The dog improved significantly while in hospital and was discharged <24 h after presentation. This is the first known reported use of IVLE for treatment of amphetamine toxicosis with documented decreases in both serum and plasma amphetamine levels shortly after administration of IVLE.
A novel LMNA mutation identified in a Japanese patient with LMNA-associated congenital muscular dystrophy
Authors: Akihiko Ishiyama, Aritoshi Iida, Shinichiro Hayashi, Hirofumi Komaki, Masayuki Sasaki, Ikuya Nonaka, Satoru Noguchi, Ichizo Nishino
Journal: Hum Genome Var (2018)
MeSH terms: Case Reports

LMNA-associated congenital muscular dystrophy (L-CMD) is a severe form of muscle laminopathy. LMNA encodes lamin A, which an intermediate filament protein that attaches to the inner membrane of the nuclear envelope. We performed sequence analysis based on our original targeted gene panel system for muscle diseases to obtain a molecular diagnosis in a Japanese girl with L-CMD. A novel heterozygous missense mutation, c.115A>C (p.Asn39His), in LMNA is reported.
Case report: The stroma-rich variant of Castleman's disease of hyaline-vascular type with atypical stromal cell proliferation and malignant potential: An exceptional rare case occurred in mediastinal lymph node
Authors: Xiaoxin Shi, Mengying Liao, Xiaomin Yin, Yaoli Chen, Chuqiang Huang, Weihua Yin, Jian Li
Journal: Front Oncol (2023)
Keywords: castleman’s disease, hyaline-vascular, malignant, p53, stromal hyperplasia
MeSH terms: Case Reports

The stroma-rich variant of Castleman disease of hyaline-vascular type (SR-HVCD) is characterized by interfollicular proliferation of the fibroblastic, myofibroblastic, and/or histiocytic-derived stromal cells, occurred in a background of Castleman disease of hyaline-vascular type (HVCD). It has been considered as a hyperplastic disorder by far. Herein, we presented a case of a 40-year-old male suffering from an occupation in the right middle mediastinum. Microscopically, the lesion was characterized by atretic lymphoid follicles and overgrowth of the interfollicular spindle-shaped cells. Those spindle cells were histologically bland in some areas, while exhibited notable cellular atypia and focal necrosis in other areas. SMA and CD68 were immunostained with a subset of the spindle cells in both areas, whereas p53 staining was only perceived in areas with markedly cellular atypia. In addition, indolent T-lymphoblastic proliferation (iT-LBP) was present inside the lesion. The patient developed multiple sites metastases 4 months after surgery, and succumbed to the disease at 7 months. Our case demonstrates for the first time that SR-HVCD have a tumorigenesis potential rather than a simple hyperplastic process. Such disorder should be carefully evaluated to avoid underdiagnosis.
COVID-19: No Guaranteed Protection from Future Infection after the Initial Diagnosis
Authors: Christopher Chew, Supriya Mannepalli
Journal: Case Rep Infect Dis (2021)
MeSH terms: Case Reports

The world of microbiology is vast in nature, and viruses continue to be a subset containing a lot of unknowns. Initial infection with certain viruses, such as varicella zoster virus and measles, allows for development of lifelong immunity; on the other hand, the influenza virus requires yearly vaccination, which may not provide adequate immunity. This can be attributed to antigenic shift and drift, rendering previously made antibodies ineffective against new strains of influenza. This article describes six cases of patients who presented with mild acute respiratory symptoms and tested positive for COVID-19 virus. After recovering from initial illness and being asymptomatic for several months, they developed recurrence of acute respiratory symptoms and, again, tested positive for COVID-19 virus, in more severe form than initial presentation. In the current state of the world, COVID-19 has created a lot of unknowns in the medical community, including patient presentation and treatment. COVID-19 research is evolving daily, but many questions remained unanswered. "Will a sufficient antibody response be created by the human body in those infected with COVID-19 and how long will that immunity last?" "Will antigenic drift occur quickly allowing the virus to evade previously made antibodies?" During initial surveillance of the COVID-19 virus, we were expecting development of an immune response comparable to SARS-CoV-1 and MERS-CoV, given the viral similarities. Unfortunately, based on our observations, this may not necessarily be true and will be further discussed in the presented article.
Laparoscopic Supracervical Hysterectomy with In-Bag Morcellation in Very Large Uterus
Authors: Harald Krentel, Rudy Leon De Wilde
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

Laparoscopic supracervical hysterectomy (LASH) is a safe and fast minimally invasive approach in hysterectomy. In order to extract the uterine body from the abdominal cavity, one condition for LASH is the morcellation of the tissue. The intra-abdominal dissemination of benign and occult malignant uterine cells is a possible risk of this method, which can be avoided by the use of special bags for laparoscopic in-bag morcellation. We present a case of laparoscopic supracervical hysterectomy with in-bag morcellation in a uterus of more than 1400 g. and describe that this minimal-access surgery is safe and feasible even in very large uteri. This case report is registered in Research Registry under the UIN researchregistry1810.