OpenMed/multicare-articles huggingface dataset:
Benign Subcutaneous Nodules and Hypereosinophilic Syndrome: A Rare Presentation of an Uncommon Entity
Authors: Rimesh Pal, Uday Yanamandra, Prasanna Kumar, Nirmalya Banerjee
Journal: Case Rep Med (2019)
MeSH terms: Case Reports

A 40-year-old gentleman presented with a history of multiple swellings involving his face, scalp, left axilla, back, and right thigh for the past 8 years. For the last 6 months, he developed intermittent low-grade fever, anorexia, weight loss, and gradually worsening breathlessness. On evaluation, the patient was found to have abnormally elevated absolute eosinophil count. Workup for the etiology of eosinophilia was unrewarding. All investigations related to an underlying myeloproliferative disorder were negative. Hence, a clinical possibility of angiolymphoid hyperplasia with eosinophilia (ALHE) was kept which was confirmed on histopathology. In the absence of other causes of hypereosinophilia, a clinical diagnosis of "associated hypereosinophilic syndrome" secondary to ALHE was made. He was managed with oral corticosteroids. The absolute eosinophil count reduced markedly, while the swellings showed a more gradual response, shrinking in size by about 50% following two months of therapy. The index case thus highlights a rather unusual presentation of ALHE.
Submacular hemorrhage secondary to congenital toxoplasmosis
Authors: Ana Luiza Fontes de Azevedo Costa, Thiago Gonçalves Dos Santos Martins, Francisco Javier Solano Moncada, Mário Martins dos Santos Motta
Journal: Einstein (Sao Paulo) (2014)
MeSH terms: Intravitreal Injections / methods, Retinal Hemorrhage / drug therapy, Retinal Hemorrhage / etiology, Toxoplasmosis, Congenital / complications, Toxoplasmosis, Congenital / drug therapy, Case Reports, Adolescent, Angiogenesis Inhibitors / administration & dosage, Antibodies, Monoclonal, Humanized / administration & dosage, Bevacizumab, Contrast Media, Female, Fluorocarbons, Humans, Time Factors, Treatment Outcome, Visual Acuity, Angiogenesis Inhibitors, Antibodies, Monoclonal, Humanized, Contrast Media, Fluorocarbons, Bevacizumab, perflutren

We report the case of a patient with congenital toxoplasmosis and submacular hemorrhage caused by a neovascular membrane who underwent an intravitreal injection of C3F8 and bevacizumab, and had a good visual recovery.
CASE REPORT Reconstruction and Characterization of Composite Mandibular Defects Requiring Double Skin Paddle Fibular Free Flaps
Authors: Austin M Badeau, Frederic W-B Deleyiannis
Journal: Eplasty (2013)

Objective:
Fibular free flaps are the preferred method for reconstruction of composite lateral mandibular defects. This reconstructive technique is limited by the skin paddle's inability to freely rotate when attempting to fill 2 poorly aligned defects. Reconstructive surgeons have been exploring multiple methods of creating 2 independent skin paddles based on the same peroneal blood supply. We present a variation of these techniques.
Method:
Our patient with a history of squamous cell carcinoma presented with a left retromolar recurrence and osteoradionecrosis of the mandible with a draining anterior sinus tract. The combination of these defects warranted further composite resection with fibular free flap reconstruction.
Results:
A subperiosteal dissection was performed to create 2 separate septocutaneous skin paddles based on the same peroneal blood supply. This dissection and discard of proximal fibula provided the rotational freedom needed for the 2 skin islands to fill both a lateral oral defect and anterior cutaneous defect.
Conclusion:
Although similar reconstructive methods have been reported in the literature, the characterization of defects benefiting from these techniques is scarce and unclear. We describe clear and concise characteristics of these defects, which should be meaningful to the reconstructive surgeon when considering operative technique.
Diagnostic challenges of an atypical presentation of ear and mastoiditis tuberculosis in a-5-year-old child in a developing country: A case report and review of literature
Authors: Elrika Anastasia Wijaya, Sally Mahdiani, Lina Lasminingrum, Heda Melinda Nataprawira
Journal: IDCases (2023)
Keywords: children, diagnosis, mastoiditis tuberculosis
MeSH terms: Case Reports

We report a case of a 5-year-old girl who came to Otolaryngology Outpatient Clinic of our hospital with the chief complaint of recurrent ear discharge which had started to appear since 3 years ago and had recurred every month despite repeated antibiotics and antifungals ear drops treatments, given by general practitioners and otolaryngologists. Gram staining, acid-fast staining and Mycobacterium tuberculosis culture examination from the discharge had never been conducted. There was a history of inadequate weight increment since she was 2 years old. Her uncle who often met her died about 6 months ago due to TB disease. She was initially diagnosed with otitis media from the previous clinicians before finally referred to our hospital due to the perforated tympanic membrane. Otoscope examination showed perforated tympanic membrane. CT scan showed right osteomastoiditis with cholesteatoma with destruction of right mastoid antrum and right ear bone. We did not find pale-looking granulomatous tissue or multiple perforated tympanic membrane. The patient was diagnosed with chronic suppurative otitis media (CSOM) of the right ear with right mastoiditis and right posterior auricle fistulae. Afterwards, canal wall up, canaloplasty, mastoid obliteration, tympanoplasty, and rotational flap right ear were performed. Histopathology examination revealed the presence of caseous necrosis and datia langhans cells. Based on her chronic illness supported by the histopathological findings, anti-tuberculosis therapy was commenced. No more ear discharge complained and her body weight started to increase after oral anti tuberculosis treatment.
Hartmann pouch herniation in Calot's triangle: A case report
Authors: Tariq Almnaizel, Tawfiq Alnawafleh, Ra'ed Al-Jarrah, Abdulhamid M Al-Abadi, Malek A Al-Omari, Eman A Al-Oudat
Journal: Int J Surg Case Rep (2020)
Keywords: calot’s triangle, hartmann pouch, laparoscopic cholecystectomy
MeSH terms: Case Reports

Introduction:
Laparoscopic cholecystectomy is one of the most frequent operations performed around the world. Some pathological findings are particularly rare and difficult to diagnose preoperatively. Here, we report a case of a patient who presented to our hospital with calculus cholecystitis with a unique Intraoperative finding of Hartmann pouch herniation through hepatocystic triangle. The aim of the study is to consider Hartmann pouch herniation as a rare differential diagnosis of gallbladder stone complication.
Presentation of case:
We present a 48-year-old male who came to our emergency department complaining of constant epigastric abdominal pain lasting 3 h with vomiting. Utilizing chemistry laboratory studies and radiological studies, the final diagnosis was acute calculus cholecystitis. Early laparoscopic cholecystectomy was done and revealed Hartmann pouch herniation through the Calot's triangle. This herniation resulted in strangulation of the Hartmann pouch and displacement of the cystic duct and artery anteriorly.
Discussion:
The biliary tract is liable for congenital anomalies. These anatomical variations can be diagnosed either intra-operatively or pre-operatively using radiological imaging. Hartmann pouch herniation is a new finding that we encountered in this case.
Conclusion:
Profound surgeons' anatomical knowledge is essential for the safety of patients, especially for hepatobiliary surgeries due to the wide variations in normal and pathological anatomy. Using critical view of safety can decrease avoidable complications. Consulting specialized hepatobiliary surgeon is preferred when dealing with such cases.
A case of large solitary fibrous tumor in the retroperitoneum
Authors: Takeo Nomura, Ryuta Satoh, Kenji Kashima, Mutsushi Yamasaki, Kenichi Hirai, Fuminori Satoh, Hiromitsu Mimata
Journal: Clin Med Case Rep (2009)
Keywords: latissimus dorsi muscle, retroperitoneum, solitary fibrous tumor
MeSH terms: Case Reports

Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm mainly originated in the pleural cavity. We report here an unusual case of a large SFT in the retroperitoneum. A 27-year-old female complaining of a palpable mass in the right flank with dull pain was admitted to our hospital with the diagnosis of right retroperitoneal tumor. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a large retroperitoneal tumor arising from latissimus dorsi muscle. Surgical findings revealed a partly encapsulated tumor and complete resection of tumor concomitantly with right kidney, 11th and 12th ribs, and diaphragm was performed. Pathological examination demonstrated the tumor to be composed of increased mitotic activity and cellularity of spindle cells with a collagenous matrix. Immunohistochemical staining was positive for CD34, vimentin, and basic fibroblast growth factor (bFGF) and negative for CD31, cytokeratin, desmin, S-100p, smooth muscle actin, Bcl-2, and insulin-like growth factor (IGF) with Ki-67 labeling index of 0.1%. Based on pathological features, diagnosis of SFT in the retroperitoneum was confirmed. To our knowledge, this is the first report of an SFT arising from latissimus dorsi muscle and it is important to include SFT in the differential diagnosis of retroperitoneal tumors that caused considerable diagnostic problems due to its unusual site of origin.
Frontal Sinus "Hump": An Anatomical Risk Factor for Anterior Skull Base Injury in the Endoscopic Modified Lothrop Approach (Outside-In Frontal Drill-Out)
Authors: Teppei Takeda, Kazuhiro Omura, Haw Torng, Teru Ebihara, Satoshi Aoki, Kosuke Tochigi, Hiromi Kojima, Nobuyoshi Otori
Journal: Case Rep Otolaryngol (2021)
MeSH terms: Case Reports

Skull base injuries caused by the outside-in frontal drill-out technique have not been reported. In this report, we chose an outside-in approach to open the frontal sinus for olfactory neuroblastoma resection. Although we identified the first olfactory fibre, the anterior skull base was damaged while drilling into the frontal sinus on the tumour side. We reconstructed the skull base in multiple layers using fascia and cartilage. Postoperative cerebrospinal fluid leakage or intracranial haemorrhage was not observed. In this case, a morphological difference existed in the posterior wall of the frontal sinus between the right and left sides, like a "hump" in the posterior wall of the frontal sinus. This case of damage to the anterior skull base that could not be avoided by identifying the first olfactory fibre alone is the first published case of skull base injury caused by the outside-in approach due to morphological variations of the frontal sinus and skull base. In this approach, the posterior wall of the frontal sinus cannot be observed because the intraoperative landmark is limited to the first olfactory fibre. Therefore, morphological variations of the posterior wall of the frontal sinus should be analysed in advance to prevent cranial base injury.
Two Consecutive Episodes of Severe Delayed Hemolytic Transfusion Reaction in a Sickle Cell Disease Patient
Authors: Clarisse Mpinganzima, Alf Haaland, Anne Guro Vreim Holm, Swee Lay Thein, Geir Erland Tjønnfjord, Per Ole Iversen
Journal: Case Rep Hematol (2020)
MeSH terms: Case Reports

Patients with sickle cell disease (SCD) suffer from anemia and painful vaso-occlusive crisis (VOC) and sometimes need blood transfusions. Delayed hemolytic transfusion reaction (DHTR) is a rare life-threatening complication observed in SCD and mimics VOC. We describe a female SCD patient undergoing three surgical procedures during which DHTR developed following the first two. Prior to a planned tonsillectomy, she received transfusion and three days after surgery developed severe hemolysis as well as pain and respiratory symptoms. On suspicion of VOC, she received additional transfusions and became hemodynamically unstable, and her hemolytic anemia worsened. Gradually, she recovered and could be discharged after two weeks; DHTR was not suspected. Sixteen months later, an arthroplasty was performed due to avascular necrosis, and again she was transfused preoperatively. Similar to the initial surgery, she developed symptoms and signs of VOC after three days, but this time, DHTR was suspected and further transfusions were withheld. Although immunosuppressive medication did not alleviate the condition, she improved on combined treatment with darbepoietin, rituximab, and eculizumab. Six months later, a second arthroplasty was performed uneventfully after prophylaxis with rituximab and without transfusion. DHTR should be considered in the presence of severe, unexplained hemolysis following a recent transfusion, and additional transfusions in this setting should be given only on vital indication.
Metastasis of colorectal adenocarcinoma to the thyroid: a case report and review of the literature
Authors: C Goatman, P J Goldsmith, V Antonopoulos, B Ali
Journal: Case Rep Surg (2012)

Purpose. We present a rare case of colorectal metastasis to the thyroid five years following primary colonic resection. This case highlights the need to be cognisant of unusual sites of metastasis from colorectal neoplasms. Case Report. An 82-year-old male patient had a panproctocolectomy for synchronous colorectal tumours. Five years later he was found to have lung and thyroid metastases found incidentally on imaging for an acute presentation with small bowel obstruction. Conclusion. Metastases to the thyroid should be considered in the differential diagnosis of the thyroid lesion with any history of malignancy, particularly with increasing patient age and when renal cell carcinoma or lung, colon, or breast primaries are involved.
Non-prostatic pathology on prostate needle-biopsy - colorectal carcinoid: a case report
Authors: Roderick Cn van den Bergh, Tineke Wolters, Manon Cw Spaander, Fritz H Schröder, Geert Jlh van Leenders
Journal: Cases J (2009)

Introduction:
Prostate needle-biopsies are among the most common specimens in routine histopathological practice; in 15% colorectal tissue is also present. Rectal pathology is described to be found in 17% of this coincidentally obtained material.
Case presentation:
We present a case in which colorectal carcinoid was found in the rectal mucosa obtained via transrectal prostate biopsies in a screening program for prostate cancer in a 71-year old Caucasian male. To the best of our knowledge, this was the first time that such a coincidental finding was discovered. Besides a colonoscopy with polypectomy, this coincidental detection remained without any further clinical consequences for this patient until today.
Conclusion:
As there is a considerable chance that abnormalities are found in the rectal tissue of prostate biopsies, it is advisable for all pathologists to include this tissue in the histology evaluation and look for potential irregularities in this simultaneously collected material.
Robotic Distal Pancreatectomy and Splenectomy for an Intrapancreatic Hepatocellular Carcinoma: A Case Report and Review of the Literature
Authors: Charles C Vining, Phillip J Hsu, Darryl Schuitevoerder, Nora E Joseph, Melissa E Hogg
Journal: J Pancreat Cancer (2020)
Keywords: hepatocellular carcinoma, pancreatectomy, robotic
MeSH terms: Case Reports

Background: Liver parenchyma that resides outside of the normal hepatic confines is defined as accessory liver if in communication with the native biliary tree, or ectopic liver (EL) if it is not. EL can develop in a variety of tissues, including but not limited to the gallbladder, the hepatic ligaments, the pancreas, and retroperitoneum. EL has an increased propensity for malignant degeneration resulting in hepatocellular carcinoma (HCC). Presentation: A 67-year-old Korean male presented with epigastric discomfort and was found to have an elevation in his transaminases. Cross-sectional imaging demonstrated a 1.3 cm solid mass in the body of the pancreas with features concerning for either a pancreatic ductal adenocarcinoma or pancreatic neuroendocrine tumor. Subsequent endoscopic ultrasound and fine needle aspiration demonstrated cells of epithelial origin with hepatocellular differentiation. A robotic-assisted distal pancreatectomy and splenectomy was performed with final pathology demonstrating a well-differentiated HCC. Conclusions: EL with malignant degeneration resulting in HCC requires surgical excision. The majority of patients reported with EL resulting in HCC in the pancreas have had the tumors located in the body and tail. Therefore, definitive treatment requires distal pancreatectomy and splenectomy. Herein, we describe the presentation, workup, and definitive treatment of HCC arising in the pancreas.
Neoadjuvant treatment of Dermatofibrosarcoma Protuberans of pancreas with Imatinib: case report and systematic review of literature
Authors: Mashaal Dhir, David G Crockett, Todd M Stevens, Peter T Silberstein, William J Hunter, Jason M Foster
Journal: Clin Sarcoma Res (2014)
Keywords: dfsp, imatinib, pancreatic metastases, systematic review
MeSH terms: Case Reports

Dermatofibrosarcoma Protuberans (DFSP) is a rare skin tumor, characterized by frequent local recurrence but is seldom metastatic. It is histologically characterized by storiform arrangement of spindle cells. Cytogenetically, most tumors are characterized by translocation 17:22 leading to overexpression of tyrosine kinase PDGFB which can be targeted with tyrosine kinase inhibitor, Imatinib. We describe the first case of unresectable pancreatic metastases from DFSP treated with neoadjuvant Imatinib and subsequently R0 metastectomy. Additionally, a comprehensive systematic review of DFSP pancreatic metastases and the current published data on the use of Imatinib in DFSP is summarized.
Invasive candidiasis presenting multiple pulmonary cavitary lesions on chest computed tomography
Authors: Yuichiro Yasuda, Kazunori Tobino, Mina Asaji, Yoshikazu Yamaji, Kosuke Tsuruno
Journal: Multidiscip Respir Med (2015)
Keywords: canididemia, computed tomography, invasive candidiasis, pulmonary cavity
MeSH terms: Case Reports

We herein report a case of invasive candidiasis presenting rare findings on chest computed tomography (CT). The chest CT scan showed multiple small cavitary lesions and nodules with surrounding ground-glass opacity, and also bilateral pleural effusion. Although this CT finding is thought as specific for pulmonary aspergillosis, two sets of blood culture specimens were drawn which yielded Candida albicans in our case. Antifungal therapy was started and the chest CT findings showed a remarkable improvement. To our knowledge, this is the first case report describing multiple pulmonary cavitary lesions in invasive candidiasis.
Myopathy with concurrent tadalafil and simvastatin
Authors: Maria Pia Gargante, Marco Vacante, Cristina Russo, Mariano Malaguarnera
Journal: Case Rep Med (2009)
MeSH terms: Case Reports

A 48-year-old man, using statin, was admitted to hospital with progressive myalgia after consumption of tadalafil and simvastatin. Muscle pain and penile erection disappeared seven days after interruption of therapy. This case demonstrates the interaction of tadalafil with simvastatin resulting in myopathy. Muscle damage could be attributed to the common metabolic way of these two drugs which is cytochrome P450 isoenzyme system.
When Nature plays upon an Ailment: A Case Report
Authors: Rani Somani, Ripin Garewal, Poonam Preet Bhandari, Dilip Kumar
Journal: Int J Clin Pediatr Dent (2012)
Keywords: marsupialization, mixed dentition, odontogenic lesion, radicular cyst, surgical enucleation
MeSH terms: Case Reports

Of the most common odontogenic cysts, radicular cysts represent cystic lesions of inflammatory origin and are managed either by surgical enucleation or by marsupialization. This article aims to report a clinical case of radicular cyst of a huge proportion treated with a conservative management. An illustration of possible complete healing of such a cystic periapical lesion in mixed dentition with conservation of vital structures is covered. How to cite this article: Somani R, Garewal R, Bhandari PP, Kumar D. When Nature plays upon an Ailment: A Case Report. Int J Clin Pediatr Dent 2012;5(1):61-63.
Postictal Psychosis: Case Report and Literature Review
Authors: Joana Regala, João Lourenço, Francisco Moniz-Pereira, António Bento
Journal: Case Rep Psychiatry (2023)
MeSH terms: Case Reports

Postictal psychosis (PIP) is one of the most common types of psychosis in epileptic patients. By virtue of the paucity of research on PIP, its pathophysiology remains not completely understood. Our case report describes a clinical picture of PIP, characterized by pleomorphic features, with neither Schneider's first-rank symptoms nor negative symptoms of schizophrenia, in a longstanding epileptic female patient with a history of nonadherence to antiepileptic treatment and poorly controlled seizures. Additionally, she had previous cognitive impairment and encephalomalacia in the right parietooccipital region as a sequela of a moderate-to-severe traumatic brain injury known to precede the emergence of the epilepsy. In light of our findings, we critically reviewed the current literature on postictal psychoses providing insight into its neurobiological underpinnings.
Massive pleural effusion following high-power and short-duration radiofrequency ablation for treatment of atrial fibrillation: A case report and review of the literature
Authors: Miaomiao He, Jie Qiu, Yang Bai, Yan Wang, Guangzhi Chen
Journal: Front Cardiovasc Med (2022)
Keywords: atrial fibrillation, diagnosis, pleural effusion, postpericardial injury syndrome, radiofrequency catheter ablation
MeSH terms: Case Reports

Postpericardial injury syndrome (PPIS) is defined as pericarditis or pericardial effusion that results from recent myocardial infarction or intracardiac interventions. These symptoms typically include fever, leukocytosis, a high erythrocyte sedimentation rate, and elevated C-reactive protein levels. Additionally, pericardial effusion and pleural effusion may be present. It is considered to be a common complication in cardio-surgery with an occurrence of 3-30%. In the past 20 years, a high number of patients with atrial fibrillation have suffered from PPIS following radiofrequency catheter ablation. However, previous reports focused on identifying cardiac tamponade and pericardial effusion as their main clinical manifestations. Solitary pulmonary involvement following PPIS with the radiofrequency catheter ablation may occur. We report a case of PPIS that presented pleural effusion as the dominant feature soon after the operation and systematic review to illustrate the clinical characteristics of PPIS.