OpenMed/multicare-articles huggingface dataset:
Appearance and management of COVID-19 laryngo-tracheitis: two case reports
Authors: Charles Matthew Oliver, Marta Campbell, Oma Dulan, Nick Hamilton, Martin Birchall
Journal: F1000Res (2020)
Keywords: airway management, covid, intensive care, sars-cov-19
MeSH terms: Coronavirus Infections / diagnosis, Pneumonia, Viral / diagnosis, Tracheitis / virology, Case Reports, Aged, Betacoronavirus, COVID-19, Coronavirus Infections / complications, Female, Humans, Middle Aged, Pandemics, Pneumonia, Viral / complications, SARS-CoV-2, Tracheitis / diagnosis, COVID-19, severe acute respiratory syndrome coronavirus 2

We present two cases of coronavirus disease 2019 (COVID-19)-related laryngotracheitis in good-prognosis, ventilated patients who had failed extubation. As the pandemic continues to unfold across the globe and better management of those with respiratory failure develops, this may be an increasingly common scenario. Close ENT-intensivist liaison, meticulous team preparation, early consideration of rigid endoscopy and prospective data collection and case sharing are recommended.
A Tibial Tubercle Fracture Masquerading as an Inferior Pole of the Patella Fracture
Authors: E Graham Englert, Muhammad Waheed, Ehab Saleh
Journal: J Am Acad Orthop Surg Glob Res Rev (2023)
MeSH terms: Knee Injuries / diagnostic imaging, Knee Injuries / surgery, Patella Fracture, Tibial Fractures / diagnostic imaging, Tibial Fractures / surgery, Case Reports, Adolescent, Child, Humans, Male, Patella / diagnostic imaging, Patella / surgery, Tibia

Pediatric tibial tubercle fractures are uncommon injuries that most often occur in adolescent men. Patients will typically present with anterior knee pain with or without patella alta. This case report describes a tibial tubercle fracture in a 13-year-old man misidentified as an inferior pole patella sleeve fracture on physical examination and preoperative radiographs. The tubercle reduction was secured with cannulated screws while injury to the patellar tendon periosteal sleeve was repaired with suture anchors. This case highlights the utility of advanced imaging when the etiology of extensor mechanism disruption is unclear. Furthermore, it is imperative to set expectations with parents and guardians that the full extent of the injury may only be confirmed under direct visualization in the operating room because of the complexity of such injuries.
Unilateral Limb Ischemia in a COVID-19 Patient: A Case Report
Authors: Qusai T Alitter, Ahmad Jarrar, Fahed AlSoud, Islam Gadelmoula
Journal: Cureus (2023)
Keywords: covid 19 - acute limb ischemia, covid-19 infection, covid-related hypercoagulability, vascular ischemia, venous and arterial thrombosis
MeSH terms: Case Reports

Coronavirus disease 2019 (COVID-19) has been primarily linked to respiratory complications, including acute respiratory distress syndrome (ARDS). However, several systemic manifestations of the disease may also occur. One of the emerging complications that is being increasingly reported in the literature is the hypercoagulable and intense inflammatory state in COVID-19 patients, which leads to venous and/or arterial thrombosis, vasospasm, and ischemia. Despite the recent advances in diagnostic and treatment modalities, the diagnosis and management of vascular ischemia in this patient population remain a challenge, resulting in increased morbidity and mortality. In this case report, we highlight the etiology and potential treatment of limb ischemia in COVID-19 patients.
Extraperineal enterocele in male: A case report and literature review
Authors: Megumi Asai, Elizabeth Wood, Craig A Reickert
Journal: Int J Surg Case Rep (2020)
Keywords: extraperineal enterocele, hedrocele, male enterocele, rectopexy
MeSH terms: Case Reports

Introduction:
Enterocele is a herniation of the small bowel through the cul-de-sac. It is uncommon and most often seen in elder females. Large enterocele manifesting as rectal prolapse is exceedingly rare and only few cases are reported previously. Due to it rarity, the best surgical treatment is not yet established especially in male patients. We present a case of enterocele causing rectal prolapse in a male patient that was treated surgically.
Presentation of case:
A 47-year-old African American male with chronic constipation and straining presented with manually reducible rectal prolapse. A defecography revealed a large enterocele prolapsing through the anterior rectal wall. The patient underwent an open posterior suture rectopexy with peritoneoplasty. His symptoms completely resolved after surgery, and repeat defecography three months after the procedure showed no sign of recurrence.
Discussion & conclusion:
Extraperineal enterocele in male is a rare disease. Rectopexy with peritoneoplasty can provide a great symptom relieve and improvement on defecography. Long-term outcome should be evaluated.
Case Report: Management of a 10-Year-Old Patient Who Presented With Infective Endocarditis and Stanford Type A Aortic Dissection
Authors: Yanxiao Liang, Mingzhi Wan, Lijie Wang, Ni Yang, Dongyu Li
Journal: Front Cardiovasc Med (2022)
Keywords: stanford type a aortic dissection, aortic sinus aneurysm ruptured, aortic valve replacement, infective endocarditis, pediatric acute aortic dissection
MeSH terms: Case Reports

A 10-year-old girl presented with a chief complaint of cyclic vomiting since the last 12 h and chest pain since the last 6 h. She was diagnosed with Stanford type A aortic dissection. Intraoperatively, the aortic valve was found to be bi-lobed, and infective endocarditis associated with aortic valve perforation and rupture of the aortic sinus aneurysm, was also observed. Therefore, she underwent aortic valve replacement due to an enlarged aortic root and aortic sinus repair. The perioperative recovery was good. A large amount of bloody pericardial effusion was found in this child pre-operatively. Therefore, early surgical intervention was necessary. Acute aortic dissection rarely occurs in children. There are no clinical guidelines for the management of pediatric aortic dissection. However, if a large pericardial effusion exists, emergency surgery is necessary and effective. The treatment of the valve should be based on the actual situation. It is best to give priority to valve molding, although valve replacement is required in the majority of cases for infective endocarditis.
Case report: Hemangioblastoma in the brainstem of a dog
Authors: Kirsten Landsgaard, Samantha St Jean, Stephanie Lovell, Jonathan Levine, Christine Gremillion, Brian Summers, Raquel R Rech
Journal: Front Vet Sci (2023)
Keywords: blood vessel, brain, canine, case report, central nervous system
MeSH terms: Case Reports

A 3-year-old castrated male, American Pit Bull Terrier presented to Texas A&M University due to a 3-week mixed cerebellar and general proprioceptive ataxia, circling, head tilt, and dull mentation. Neurologic examination revealed signs of vestibular and mesencephalic dysfunction. Postmortem examination revealed a 1.1 × 1 × 0.8-cm, soft, dark red, well-circumscribed, left-sided mass, extending from the crus cerebri of the midbrain caudally to the pons. Microscopically, the neoplasm was composed of a spindle-shaped interstitial population of cells interspersed between a prominent capillary network, consistent with the reticular pattern of hemangioblastoma. Interstitial cells had strong, diffuse, intracytoplasmic immunolabeling for neuron-specific enolase (NSE) and were variably positive for intracytoplasmic glial fibrillary acidic protein (GFAP). Vascular endothelial cells had strong diffuse, intracytoplasmic immunolabeling for von Willebrand factor (VWF) glycoprotein. To date, only six cases of hemangioblastoma have been reported in canines, five in the spinal cord, and one in the rostral cerebrum. Our case may represent the first canine hemangioblastoma localized to the brainstem.
Case Report: A Case of Eyelid Myoclonic Status With Tonic-Clonic Seizure and Literature Review
Authors: Yujun Yuan, Fenghua Yang, Liang Huo, Yuying Fan, Xueyan Liu, Qiong Wu, Hua Wang
Journal: Front Pediatr (2021)
Keywords: jeavons syndrome, eye closure sensitivity, eyelid myoclonus, photosensitiveness, status epilepticus
MeSH terms: Case Reports

Eyelid myoclonus with or without absence epilepsy is a rare and usually misdiagnosed disease in the neurology department. It is an idiopathic general epileptic syndrome, the onset period is 6-8 years, and is more common in girls. It is characterized by rapid abnormal eye blinking, accompanied by upward rolling of the eye and slight backward movement of the head, with eye closure sensitivity and photosensitivity. The seizure is frequent and short, dozens or even hundreds of times a day; a small number of patients may have eyelid myoclonus status. We report a patient who visits the hospital for the first time with eyelid myoclonic problem; the patient continued to wink the eyes, eye rolled up, and backward movement of the head, accompanied by impairment of consciousness. Video electroencephalography (VEEG) suggests continued spike slow-wave, polyspike slow-wave. After the patient had 2, 4, 6, 8, 10, 12, and 14 Hz of intermittent photic stimulation (IPS), her seizures and epileptic discharges reduced or stopped. Seven min after giving stimulation at 20 Hz, the child developed an occipital-initiated tonic-clonic seizure, which demonstrated that after sufficient IPS stimulation, the occiput cortex became excited and initiated a brain network, leading to diffuse brain discharge and tonic-clonic seizures. At 1 h after onset, the child developed a nonconvulsive state, with impairment of consciousness despite no eyelid myoclonic movements, and VEEG suggested a large number of epileptic discharges. After 10 min of administrating midazolam, the patient's EEG immediately became normal, and the patient regained consciousness. Therefore, this paper presents an eyelid myoclonus status patient with occipital origin seizure, we recorded the whole course of the disease and the treatment effect, and reviewed the literature accordingly.
Metastasis to Paranasal Sinuses from Carcinoma of Prostate: Report of a Case and Review of the Literature
Authors: Elio Bittar Barbosa, Evaldo César Macau Furtado Ferreira, Fernanda Viviane Mariano, Albina Messias de Almeida Milani Altemani, Emerson Taro Inoue Sakuma, Eulalia Sakano
Journal: Case Rep Otolaryngol (2018)
MeSH terms: Case Reports

Metastasis from distant primary tumors is extremely rare in the paranasal sinuses with few hundred cases in the literature. Metastatic carcinoma of the prostate is even rarer, despite being one of the most common tumors, with only 24 cases published. In this article, we report a case of a 58-year-old male presenting with epistaxis and nasal obstruction as initial symptoms of a metastatic prostate carcinoma in the ethmoid cells and maxillary sinus.
Adult Onset Still's Disease and Rocky Mountain Spotted Fever
Authors: Paul Persad, Rajendrakumar Patel, Niki Patel
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

Adult Still's Disease was first described in 1971 by Bywaters in fourteen adult female patients who presented with symptoms indistinguishable from that of classic childhood Still's Disease (Bywaters, 1971). George Still in 1896 first recognized this triad of quotidian (daily) fevers, evanescent rash, and arthritis in children with what later became known as juvenile inflammatory arthritis (Still, 1990). Adult Onset Still's Disease (AOSD) is an inflammatory condition of unknown etiology characterized by an evanescent rash, quotidian fevers, and arthralgias. Numerous infectious agents have been associated with its presentation. This case is to our knowledge the first presentation of AOSD in the setting of Rocky Mountain Spotted Fever. Although numerous infectious agents have been suggested, the etiology of this disorder remains elusive. Nevertheless, infection may in fact play a role in triggering the onset of symptoms in those with this disorder. Our case presentation is, to our knowledge, the first case of Adult Onset Still's Disease associated with Rocky Mountain spotted fever (RMSF).
Case Report: Postoperative Recurrence of Adrenal Epithelioid Angiosarcoma Achieved Complete Response by Combination Chemotherapy With Liposomal Doxorubicin and Paclitaxel
Authors: Hangping Wei, Jie Mao, Yandan Wu, Qinfei Zhou
Journal: Front Oncol (2021)
Keywords: adrenal gland, combination chemotherapy, epithelioid angiosarcoma, liposomal doxorubicin, paclitaxel
MeSH terms: Case Reports

Background:
Primary adrenal epithelioid angiosarcoma is an extremely rare cancer with a poor prognosis. Because of the rarity of this disease, treatment options have not been well-studied.
Case presentation:
A 51-year-old man was admitted to Zhejiang Cancer Hospital, diagnosed with a recurrence of adrenal epithelioid angiosarcoma. He had undergone a surgical resection seven months earlier. Combination chemotherapy with liposomal doxorubicin and paclitaxel was administered. After two cycles of chemotherapy, his pain was relieved. Computed tomography (CT) suggested that the soft tissue tumour lesions in the surgical area had disappeared, mediastinal and mediastinal-hilar lymph nodes were significantly reduced or had disappeared, and the patient had achieved a partial response (PR). CT after six cycles of chemotherapy indicated that the patient had achieved a complete response (CR).
Conclusion:
Combination chemotherapy with liposomal doxorubicin and paclitaxel may be a preferred therapy for recurrent or advanced adrenal epithelioid angiosarcoma.
Congenital unilateral corneal anaesthesia with microphthalmos: a case report
Authors: George Voyatzis, Achyut Mukherjee, Madhavan S Rajan, Louise E Allen
Journal: Case Rep Ophthalmol Med (2012)
MeSH terms: Case Reports

Congenital corneal anaesthesia (CCA) is an uncommon condition difficult to diagnose. We report the case of a 20-month-old boy who presented with unilateral congenital corneal anaesthesia. The child was referred with a persistent corneal epithelial defect, unresponsive to symptomatic local treatment for over 10 months. Intensive topical treatment and strict corneal protection led to quick corneal healing. Congenital corneal anaesthesia occurs either alone or in association with neurological diseases or systemic congenital abnormalities. It is important to search for corneal anaesthesia in children with chronic ulcerations of the cornea and self-inflicted injuries. Early diagnosis and treatment are important due to the risk of poor visual prognosis. Management of CCA should aim for the prevention of epithelial defects and is a life-long process.
Sellar spine: A rare Bony variant of the Sella Turcica
Authors: Luke D Metelo-Liquito, Thandi E Buthelezi
Journal: SA J Radiol (2022)
Keywords: bony variant, hypoprolactinaemia, pituitary fossa, sella turcica, sellar spine
MeSH terms: Case Reports

A sellar spine is a rare osseous projection from the dorsum sellae, resulting in variable compression of sellar and suprasellar structures and varied clinical presentations. CT is the diagnostic modality of choice, while variable signal intensity on MRI may mimic a pituitary microadenoma. A patient presented with hypoprolactinaemia and puerperal alactogenesis due to a sellar spine diagnosed on CT Brain. Neurosurgical and endocrine review and pituitary MRI were recommended with subsequent loss to follow-up.
A Case of Undetected Neuroborreliosis in a 75-Year-Old Chinese Male
Authors: Jenny Lamichhane, Rohail Haider, Michael Bekkerman, Sean Tilford, Shireen Hijaz, Bikash Bhattarai, Rajanish Bobde
Journal: Case Rep Infect Dis (2018)
MeSH terms: Case Reports

Lyme disease is a multisystem infection caused by the spirochete Borrelia burgdorferi sensu stricto that manifests with characteristic symptoms in patients. Patients are identified based on their clinical symptoms and then diagnosed through enzyme-linked immunosorbent assay (ELISA), Western blot, and blood culture techniques. Here, we present the case of a 75-year-old, Northeast suburban resident complaining of unstable gait, high fevers, malaise, myalgia, and confusion. This patient's symptoms were nonspecific, and his lab titers and blood cultures were repeatedly negative during his stay. It was only late in the course of his treatment that blood titers and cerebrospinal fluid analysis were positive for Lyme IgG and IgM. He was treated with intravenous doxycycline and prescribed oral doxycycline on discharge, resulting in a full recovery. We express the need for physicians to consider Lyme disease in endemic patients presenting with nonspecific systemic signs.
Case report: Sulfasalazine-induced hypersensitivity
Authors: Ekaterina M Kuchinskaya, Irina A Chikova, Mikhail M Kostik
Journal: Front Med (Lausanne) (2023)
Keywords: dihs, dress, drug reaction with eosinophilia and systemic symptoms, drug-induced hypersensitivity syndrome, serious adverse events, sulfasalazine
MeSH terms: Case Reports

Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is a systemic inflammatory condition that is characterized by multisystemic involvement (liver, blood, and skin), heterogeneous manifestations (fever, rash, lymphadenopathy, and eosinophilia), and an unpredictable course; cases of DiHS/DRESS caused by sulfasalazine are rare in children compared to adults. We report a case of a 12-year-old girl with juvenile idiopathic arthritis (JIA) and sulfasalazine-related hypersensitivity who developed fever, rash, blood abnormalities, and hepatitis complicated with hypocoagulation. The treatment with intravenous and then oral glucocorticosteroids was effective. We also reviewed 15 cases (67% male patients) of childhood-onset sulfasalazine-related DiHS/DRESS from the MEDLINE/PubMed and Scopus online databases. All reviewed cases had a fever, lymphadenopathy, and liver involvement. Eosinophilia was reported in 60% of patients. All patients were treated with systemic corticosteroids, and one patient required emergency liver transplantation. Two patients (13%) died. A total of 40.0% of patients satisfied RegiSCAR definite criteria, 53.3% were probable, and 80.0% satisfied Bocquet's criteria. Only 13.3% satisfied typical and 20.0% atypical DIHS criteria from the Japanese group. Pediatric rheumatologists should be aware of DiHS/DRESS due to its similarities to other systemic inflammatory syndromes (especially systemic JIA, macrophage activation syndrome, and secondary hemophagocytic lymphohistiocytosis). Further studies of DiHS/DRESS syndrome in children are needed to improve its recognition and differential diagnostic and therapeutic options.
A National Early Intervention System as a Strategy to Promote Inclusion and Academic Achievement in Portugal
Authors: Vitor Franco, Madalena Melo, Graça Santos, Ana Apolónio, Leonor Amaral
Journal: Front Psychol (2017)
Keywords: early intervention, developmental psychopathology, inclusion, school achievement, social network

Early intervention with children at risk or facing developmental problems is a practice defined by three fundamental characteristics: being family-centered, being based on the community and on the child's life context, and being conducted by a team with transdisciplinary practice. In this paper we wish to present how the SNIPI-National System of Early Intervention, implemented in Portugal over the past 15 years, contributes to promote maximum development and the full inclusion of children up to 6 years of age and works to prevent school failure. The SNIPI covers the entire territory and intends to respond to the needs of children with developmental disorders or those in at risk situations. This community-based early intervention model is linked to the health, education and social care systems, involving the three responsible Ministries. In the present community case study, we present the implementation of this program in the Alentejo region, involving 31 local teams and almost 2500 children. Through the regional structure's reports and the responses of parents and professionals in impact studies, we demonstrate how the system is established and how it tackles school failure and improves the educational inclusion of these children. The impact of this Early Intervention model has been significant not only on children's developmental outcomes, but also for the health, education and social care professionals who work in a transdisciplinary perspective, as well as for the families who became more skilled at evaluating the children's needs and the support provided. This approach to implementing a family-centered Early Intervention program can contribute to full inclusion. It facilitates the transition to schooling based on a non-discriminatory approach and educational achievement by aiding development and an adapted contextualization in pre-school education. This program system introduces significant innovation within the framework of existing educational policies that promote development and inclusion, and has therefore earned the interest of the scientific community and policy-makers alike. It has been possible to implement some of principles already studied but it had never been tested. The Early Intervention program in Alentejo, as part of the SNIPI, can be an example of good practices, with its own characteristics that allowed to create a network of integrated and comprehensive responses to the needs of the population in this region.
A Rare Culprit of Infective Endocarditis in an IV Drug User: Burkholderia cepacia
Authors: Christopher Nnaoma, Ogechukwu Chika-Nwosuh, Christoph Sossou
Journal: Case Rep Med (2019)
MeSH terms: Case Reports

Infective endocarditis (IE) is an infection of the cardiac native or prosthetic valves typically caused by Staphylococcus aureus, viridans streptococci group, and coagulase-negative staphylococci. Risk factors include congenital heart disease, structural and valvular heart disease, implantation of prosthetic heart valves, and intravenous (IV) drug abuse. IE caused by organisms such as Burkholderia cepacia is rarely seen. We herein present a case of a patient with a history of IV drug abuse previously treated for Staphylococcus aureus IE with newly diagnosed IE secondary to B. cepacia. He was taken to the operating room for mitral valve replacement after an echocardiogram revealed severe mitral regurgitation. He was successfully treated with antibiotics. After 2 months, at follow-up, the patient remained free from mechanical valve-related events, had no new occurrences of fever, and had no other symptoms of infection. He reported good exercise tolerance.
Bispectral Index Changes during Acute Brainstem TIA/Ischemia
Authors: Chris P Bleeker, Bart Smits, Pieter E Vos, Jo M J Mourisse
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

We describe a 76-year-old patient who suffered a brainstem TIA just before being anesthetised for cardiac surgery. The TIA was registered on BIS and resulted in a drop in BIS to a value of 60. When consciousness returned spontaneously, the BIS increased to 85. The relative use of the BIS during an operation is discussed. We believe that the lack of input from the brainstem to the frontal cortex resulted in the reduced cortical electrical activity as registered with the BIS.
Computed tomographic diagnosis of aortocaval fistula
Authors: Navdeep Singh, Aneesh Mangalasseril Kuriakose, Regi An George, Shirish Vaidya
Journal: SA J Radiol (2018)
MeSH terms: Case Reports

Aortocaval fistula is an abnormal vascular communication between an aortic aneurysm and the inferior vena cava. The condition is very rare and life threatening with high mortality. This article reports a case of aortocaval fistula in a 76-year-old male diagnosed using computed tomography. Computed tomography, being a non-invasive investigation, ensures early diagnosis and can help in prompt surgical or interventional radiological management which can be life-saving.