OpenMed/multicare-articles huggingface dataset:
Embryologic Association of Tornwaldt's Cyst with Cerebral Artery Abnormalities and Infarction: A Case Report
Authors: Michael F Osborn, Benjamin K Buchanan, Nassim Akle, Ahmed Badr, Jun Zhang
Journal: Case Rep Pediatr (2012)

Background and Purpose. Tornwaldt's cysts are rare nasopharyngeal lesions that develop from remnants of the embryonic notochord. Summary of Case. We reported a twelve-year-old female stroke patient with Tornwaldt's cysts, whose father also suffered a stroke at age fifty two with the presence of an abdominal aortic aneurysm, suggesting a genetic influence in this case. Conclusions. This paper suggests an etiologic connection between Tornwaldt's cysts and cerebral vasculature abnormalities by way of notochordal dysfunction during development, likely the result of perturbation of notochord-derived molecular cues during development or biogenesis.
Advanced Marjolin's ulcer of the scalp in a 13-year-old boy treated by excision and free tissue transfer: Case report and review of literature
Authors: M Daya, T Balakrishan
Journal: Indian J Plast Surg (2009)
MeSH terms: Case Reports

Marjolin's ulcer originates in chronic scars and wounds of diverse origin. This relatively rare tumour is most commonly a squamous cell carcinoma. The reason for malignant transformation is not well understood. The burn scar is a common predilection. We present the youngest patient in the literature, a 13-year-old male with a locally advanced squamous cell carcinoma of the scalp with intracranial extension following an unhealed burn injury at the age of three. Bilateral cervical lymphadenopathy was also noted. The tumour was excised and the large defect overlying the brain was covered by free latissimus dorsi musculocutaneous flap. At four weeks a therapeutic bilateral selective neck dissection was done. Adjuvant chemotherapy was administered. This report reiterates the importance of early diagnosis. Free tissue transfer further enhances our ability to cover complex defects associated with excision of advanced lesions.
A Rare Case of Extensive Eggshell Intestinal Wall Peritoneal Calcification in a Long-Term Continuous Peritoneal Dialysis Patient
Authors: Erasmia Sampani, Chrysostomos Dimitriadis, Efstratios Kasimatis, Evangelos Memmos, Aikaterini Papagianni
Journal: Case Rep Nephrol (2022)
MeSH terms: Case Reports

Encapsulating peritoneal sclerosis (EPS) is a rare but rather serious complication of long-term peritoneal dialysis. The etiology of EPS is multifactorial, with long-term peritoneal dialysis, multiple peritonitis episodes, and uncontrolled hyperparathyroidism considered to be major risk factors for this often life-threatening condition. We report a case of a 55-year-old female patient with Down syndrome and end-stage renal disease (ESRD) on long-term peritoneal dialysis (PD) with extensive intestinal peritoneal calcifications and a rather uncomplicated long follow-up.
X-LINKED ADRENOLEUKODYSTROPHY IN BRAZIL: A CASE SERIES
Authors: Fernanda Luiza Schumacher Furlan, Macleise Andres Lemes, Ligia Cecilia Fuverki Suguimatsu, Carolina Teixeira Furquim Pires, Mara Lucia Schmitz Ferreira Santos
Journal: Rev Paul Pediatr (2019)
MeSH terms: Adrenoleukodystrophy / complications, Adrenoleukodystrophy / diagnosis, Adrenoleukodystrophy / epidemiology, Adrenoleukodystrophy / therapy, Adolescent, Brazil / epidemiology, Child, Cross-Sectional Studies, Humans, Phenotype, Young Adult

Objective:
To describe patients with different phenotypes of X-linked adrenoleukodystrophy: pre-symptomatic, cerebral demyelinating inflammatory adrenoleukodystrophy, adrenomyeloneuropathy and adrenal insufficiency only.
Methods:
Specific data related to epidemiology, phenotype, diagnosis and treatment of 24 patients with X-linked adrenoleukodystrophy were collected. A qualitative cross-sectional and descriptive-exploratory analysis was performed using medical records from a reference center in Neuropediatrics in Curitiba, Brazil, as well as an electronic questionnaire.
Results:
The majority (79%) of patients had cerebral demyelinating inflammatory adrenoleukodystrophy, presenting aphasia, hyperactivity and vision disorders as the main initial symptoms. These symptoms appeared, on average, between six and seven years of age. There was a mean delay of 11 months between the onset of symptoms/signs and the diagnosis. Patients sought diagnosis mainly with neuropediatricians, and the main requested tests were dosage of very long chain fatty acids and brain magnetic resonance.
Conclusions:
All phenotypes of X-linked adrenoleukodystrophy, except for myelopathy in women, were presented in the studied population, which mainly consisted of children and adolescents. Prevalent signs and symptoms registered in the literature were observed. Most of the patients with cerebral demyelinating inflammatory adrenoleukodystrophy were not diagnosed in time for hematopoietic stem cell transplantation.
Modified Arthroscopic Suture Fixation of Posterior Cruciate Ligament Tibial Avulsion Fracture in the Setting of Multiligament Knee Injury in Teenager
Authors: Miguel Quesado, Ana Sofia Esteves, Nuno Vieira da Silva, Tiago Costa, Nuno Ferreira, Hélder Nogueira
Journal: Case Rep Orthop (2021)
MeSH terms: Case Reports

The posterior cruciate ligament (PCL) avulsion fracture is a rare injury and occurs mainly in young patients. The development of arthroscopic techniques and fixation methods has improved the treatment of this entity. This report describes a modified arthroscopic suture fixation of a small tibial avulsion fracture of the PCL. A 17-year-old male, injured in a motorcycle crash, was admitted to the Emergency Department and diagnosed with left knee PCL tibial avulsion fracture, lateral collateral ligament (LCL) femoral avulsion fracture, and patella fracture. The PCL was fixed arthroscopically using a Knee Scorpion and two SutureTapes (Arthrex, Munich-Germany) through of an interlaced configuration at the base of the fragment using a transseptal approach and fixed distally over a cortical button on the anterior cortex. The LCL was repaired with two cannulated screws by a percutaneous approach. At 1 year of follow-up, the fragment was healed with tibiofemoral congruence, and the knee was stable with complete range of motion. The Tegner Lysholm Knee Scoring Scale (TLKSS) was 92.
Aneurysm of the Pulmonary Artery in Fallot's Tetralogy
Authors: Kawtar Afrikh, Loua Hattach, Nadia Fellat, Mustapha El Bakkali, Halima Benjelloun
Journal: Case Rep Cardiol (2017)
MeSH terms: Case Reports

Introduction:
Pulmonary artery aneurysms are a rare entity. Etiologies of these findings are multiple, but they are exceptionally associated with Fallot's Tetralogy. In this study, we present an unusual case of an important aneurysm of the left pulmonary artery associated with Fallot's Tetralogy disease.
Case presentation:
A 30-year-old woman has been admitted for dyspnea and cyanosis. The data which had been obtained from echocardiography, cardiac catheterization, and angio-magnetic resonance imaging (MRI) suggested the existence of an important aneurysm of the left pulmonary artery associated with a regular Fallot's disease with a pulmonic stenosis. We have noticed the presence of a small restrictive patent ductus arteriosus (PDA). Therefore, the patient was referred to surgical correction.
Conclusion:
Pulmonary artery aneurysms associated with Fallot's Tetralogy are rarely reported. The natural history of these rare arterial aneurysms has to be clarified.
Anti-MuSK-Positive Myasthenic Crisis in a 7-Year-Old Female
Authors: Harrison J Matthews, Apisadaporn Thambundit, Brandon R Allen
Journal: Case Rep Emerg Med (2017)
MeSH terms: Case Reports

A seven-year-old African American female with anti-MuSK-positive Juvenile Myasthenia Gravis collapsed while at school from progressively worsening weakness and dyspnea. On initial emergency department presentation, she required 15 liters per minute of supplemental oxygen to maintain oxygen saturation above 92%. Initial pulmonary function tests and venous blood gas led to the decision to place her on noninvasive positive pressure ventilation (NPPV) with BiPAP in the emergency department. Due to worsening hypercarbia, she later required mechanical intubation in the PICU and underwent IVIG therapy followed by plasmapheresis in order to achieve a stable discharge from the hospital. A respiratory virus panel PCR was positive for influenza A, influenza B, and rhinovirus, likely precipitating the respiratory failure and myasthenic crisis in this seven-year-old patient. Given the rarity of this condition, this case report is to provide further education to the clinician managing severe, prepubertal Juvenile Myasthenia Gravis and myasthenic crisis.
2-[¹⁸F]fluoro-2-deoxy-D-glucose (FDG) positron-emission tomography (PET) findings of chronic expanding intrapericardial hematoma: a potential interpretive pitfall that mimics a malignant tumor
Authors: Hiroyuki Tokue, Azusa Tokue, Kenzo Okauchi, Yoshito Tsushima
Journal: J Cardiothorac Surg (2013)
MeSH terms: Fluorodeoxyglucose F18, Heart Diseases / diagnostic imaging, Hematoma / diagnostic imaging, Pericardium / diagnostic imaging, Radiopharmaceuticals, Case Reports, Aged, Heart Diseases / pathology, Heart Diseases / surgery, Hematoma / pathology, Hematoma / surgery, Humans, Male, Pericardium / pathology, Pericardium / surgery, Positron-Emission Tomography / methods, Radiopharmaceuticals, Fluorodeoxyglucose F18

A 77-year-old man who had undergone mitral valve replacement 5 years previously presented with an intrapericardial mass. Computed tomography and magnetic resonance imaging showed that the mass lesion contained hematoma components. Positron-emission tomography (PET) with 2-[¹⁸F]fluoro-2-deoxy-D-glucose (FDG) revealed uptake in the peripheral rim of the mass. These findings suggested the presence of hematoma associated with a malignant lesion. Surgical resection was performed, and the histological diagnosis was chronic expanding intrapericardial hematoma without neoplastic changes. Chronic expanding intrapericardial hematoma is a rare disease but should be considered when an expanding mass is found in a patient after cardiac surgery. The FDG-PET findings of chronic expanding hematomas, including FDG uptake in the peripheral rim of the mass as a result of inflammation, should be recognized as a potential interpretive pitfall that mimics a malignant tumor.
Postoperative intestinal intussusception in children, an easily missed culprit of postoperative intestinal obstruction: Case series and literature review
Authors: Sadi A Abukhalaf, Tareq Z Alzughayyar, Muath A Baniowda, Radwan Abukarsh, Ihsan Ghazzawi, Nathan M Novotny, Ahmad Al Hammouri
Journal: Int J Surg Case Rep (2019)
Keywords: ileocolic, ileoileal, poi, postoperative intestinal intussusception, postoperative intestinal obstruction

Background:
Postoperative intestinal intussusception (POI) is a rare cause of intestinal obstruction with POI after surgical reduction of ileocolic intussusception being an extremely rare variant. POI was reported to follow many abdominal and non-abdominal operations. A late diagnosis can risk ischemia and necrosis. POI also increases the morbidity and mortality, rendering an early diagnosis and prompt management as lifesaving.
Methods:
We reviewed the medical charts retrospectively for the last ten years for patients with POI at Palestine Red Crescent Society Hospital, Hebron, Palestine. We reviewed the literature and presented the characteristics of the most reported cases of POI following surgical reduction of ileocolic intussusception.
Results:
We presented three cases of ileoileal POI and one case of ileocolic POI followed different primary operations. All but one patient presented in the first two weeks. The delayed presentation came two months after revision of a prolapsed colostomy. All patients managed successfully with operative manual reduction with no postoperative complications. Initially, we had struggles in the diagnosis of POI largely due to a low suspicion for this rare entity, but thereafter we kept POI in mind and managed the after-coming cases in an expeditious manner.
Conclusion:
Frequently, POI is misdiagnosed as postoperative adhesive obstruction. POI is challenging in diagnosis and needs a very high index of suspicion, mainly due to its rarity and atypical presentation. By keeping the possibility of POI in mind, one can easily diagnose it and prevent its consequences.
CD19 and CD70 Dual-Target Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Relapsed and Refractory Primary Central Nervous System Diffuse Large B-Cell Lymphoma
Authors: Sanfang Tu, Xuan Zhou, Zhenling Guo, Rui Huang, Chunyan Yue, Yanjie He, Meifang Li, Yiran Chen, YuChen Liu, Lung-Ji Chang, Yuhua Li
Journal: Front Oncol (2019)
Keywords: cd19, cd70, central nervous system (cns), chimeric antigen receptor (car), diffuse large b-cell lymphoma (dlbcl)
MeSH terms: Case Reports

Background: The therapeutic efficacy of chimeric antigen receptor (CAR) T-cells targeting CD19 has been illustrated in the treatment of diffuse large B-cell lymphoma (DLBCL). However, there is a 21-35% relapse rate after anti-CD19 CAR T-cell induced remission. In addition, CAR T-cell therapy has severe adverse reactions, such as cytokine release syndrome (CRS) and CART-related encephalopathy syndrome (CRES). Because of the potential mortality associated with severe CRES, patients with primary central nervous system lymphoma (PCNSL) are usually excluded from clinical trials involving CAR T-cell therapy. Here, we report a case of refractory and relapsed primary central nervous system diffuse large B-cell lymphoma (PCNS-DLBCL). Case Presentation: The patient is a 67-year-old male who was diagnosed with PCNSL in 2011. He achieved complete remission (CR) after receiving 6 cycles of temozolomide and high-dose methotrexate. In December 2016, he experienced his first relapse and was treated with surgery and multicourse chemotherapy. He achieved CR again after the treatment. However, he experienced a second relapse in August 2017. MRI revealed a residual mass of 26 mm*35 mm*30 mm on the right side of the post-operative cavity and stale hemorrhage in the left basal ganglia. After confirming the expression of CD19 and CD70 in his tumor samples, the patient was given lymphodepletion chemotherapy followed by infusion of 4th generation CD19-CAR T-cells (4SCART19) and 4th generation CD70-CAR T-cells (4SCART70). One month later, the patient had symptomatic improvement, and brain MRI showed CR. Both CART19 and CART70 cells were detected in the 10th month after CAR T-cell infusion. Notably, neither CRS nor CRES occurred during treatment and follow-up. To date, the patient has maintained disease-free survival with more than 17 months of follow-up. Conclusions: The results of this study indicate that combination of CD19- and CD70-specific CAR T-cells may effectively target PCNSL and maintain disease-free survival without inducing CRS or CRES. Therefore, central nervous system lymphoma is not an absolute contraindication for dual-target CAR T-cell therapy.
Pneumococcal bacteremia presenting as acute parotitis and sepsis
Authors: Ashish Kataria, Alan S Multz
Journal: Case Rep Med (2009)
MeSH terms: Case Reports

We report a case of a 33-year-old female with history of Systemic Lupus Erythematosus (SLE) presenting with acute febrile illness and unilateral parotid gland enlargement progressing to septic shock. The chest imaging showed bilateral multilobar infiltrates and Pneumococci were identified in the blood cultures. The patient was treated with broad-spectrum antibiotics. The underlying imunosupression caused by SLE and long-term steroid treatment could have predisposed this patient to invasive Pneumococcal disease.
Hidden chromosomal abnormalities in pleuropulmonary blastomas identified by multiplex FISH
Authors: Benoit Quilichini, Nicolas Andre, Corinne Bouvier, Marie-Anne Chrestian, Angelique Rome, Dominique Intagliata, Carole Coze, Gabriel Lena, Helene Zattara
Journal: BMC Cancer (2006)
MeSH terms: Chromosome Aberrations, Lung Neoplasms / genetics, Lung Neoplasms / pathology, Pulmonary Blastoma / genetics, Pulmonary Blastoma / pathology, Case Reports, Child, Preschool, Female, Humans, In Situ Hybridization, Fluorescence / methods, Lung Neoplasms / therapy, Male, Neoplasm Recurrence, Local, Prognosis, Pulmonary Blastoma / therapy

Background:
Pleuropulmonary blastoma (PPB) is a rare childhood dysontogenetic intrathoracic neoplasm associated with an unfavourable clinical behaviour.
Cases presentation:
We report pathological and cytogenetic findings in two cases of PPB at initial diagnosis and recurrence. Both tumors were classified as type III pneumoblastoma and histological findings were similar at diagnosis and relapse. In both cases, conventional cytogenetic techniques revealed complex numerical and structural chromosomal abnormalities. Molecular cytogenetic analysis (interphase/metaphase FISH and multicolor FISH) identified accurately chromosomal aberrations. In one case, TP53 gene deletion was detected on metaphase FISH. To date, only few cytogenetic data have been published about PPB.
Conclusion:
The PPB genetic profile remains to be established and compared to others embryonal neoplasia. Our cytogenetic data are discussed reviewing cytogenetics PPBs published cases, illustrating the contribution of multicolor FISH in order to identify pathogenetically important recurrent aberrations in PPB.
Computer assisted total knee arthroplasty for osteoarthritis to secondary to congenital dislocation of the patella: A case report
Authors: Kwangkyoun Kim
Journal: Int J Surg Case Rep (2018)
Keywords: computer assisted surgery, congenital dislocation of patella, knee, osteoarthritis, total knee arthroplasty

Introduction:
Late presentation of congenital patella dislocation (CPD) with advanced osteoarthritis is very rare. Total knee arthroplasty (TKA) provides a valid treatment option for adults with CPD who have absence of the femoral sulcus and associated osteoarthritis. TKA for knee with CPD demand more precise technique because TKA correct the unusual pathologies for primary osteoarthritis, eg, tibial external rotation, absence of femoral groove, patella hypoplasia, and realignment of extensor mechanism.
Case presentation:
This case is a CPD with advanced osteoarthritis of left knee in a seventy-two-year old woman. We used a computer assisted navigation for a restoration of alignment, extension and flexion gap balancing, and mediolateral symmetry in the TKA, and operated it successfully.
Conclusion:
TKA is a useful procedure for osteoarthritis of the knee in association with CPD. In hard case of osteoarthritis with CPD, computer assisted navigation is a useful tool for the TKA.
Extra-lobar Pulmonary Sequestration Requiring Intrauterine Thoracentesis
Authors: Ufuk Cakir, Dilek Kahvecioglu, Serdar Alan, Duran Yildiz, Hasan Akduman, Omer Erdeve, Gulnur Gollu Bahadir, Meltem Kologlu, Begum Atasay, Saadet Arsan
Journal: APSP J Case Rep (2015)
Keywords: congenital lung malformations, extra-lobar pulmonary sequestration, fetal pleural effusion
MeSH terms: Case Reports

Congenital lung malformations can result in significant morbidity and mortality in children. Pulmonary sequestration is an uncommon congenital malformation of the lung that can cause complications even in fetal life. We herein present a newborn with extra-lobar sequestration (ELS) that lead to hydrops fetalis necessitating fetal intervention.
Detecting informal green, blue, and street physical activity spaces in the city using geotagged sports-related Twitter tweets
Authors: Charlotte van der Lijn, Emil Ehnström, Sonja Koivisto, Petteri Muukkonen
Journal: Front Sociol (2023)
Keywords: twitter, geotag, informal sports, physical activity, urban planning, wellbeing

Introduction:
Finland's natural physical environment and climate support a wide variety of informal outdoor sports, thereby motivating the population to do physical exercise in scenic environments. The vast majority of Finns enjoys outdoor recreational activities, and could thus be encouraged to post accounts of their year-round activities on social media. Our aim was to find out in what kind of areas and spaces, spatially, users are tweeting about sporting activities.
Methods:
We use geotagged Twitter tweets filtering for 16 sporting activity keywords in both English and Finnish. The case study was conducted in the Helsinki Metropolitan Area, Finland, with an emphasis on cross-country skiing as a sports activity when there is snow. In a secondary analysis we concentrated on the sports people were practicing in these locations when there was no snow. The location spaces are split in to three land cover types: green, blue, and street spaces.
Results:
We found that approximately half of the 150 skiing-related tweets were geotagged in green spaces, and half in street spaces. This finding related to street space was attributable to a spatial scale error: when we checked the results manually we noticed that they referenced the sporting location in the green space. Hence, then over 90% of the 745 non-ski-related tweets were geotagged in a street space.
Discussion:
We conclude that Twitter is a beneficial tool for detecting spaces used for informal physical activity. A shortcoming in current Finnish national sporting policies is that spaces for informal physical activity are not explicitly mentioned- we use the term informal with reference both to the space and to the sporting activity, whereby public spaces are used for physical activity. This new knowledge of sporting locations will help city planners and sports planners to improve informal sports facilities, which in turn will promote healthy exercise in cities.
An Unusual Case of Hereditary Neuropathy With Liability to Pressure Palsy: A Diagnostic Challenge
Authors: Kumar Saurabh, Reyaz Ahmad
Journal: Cureus (2023)
Keywords: atypical cidp, chronic inflammatory demyelinating polyneuropathy (cidp), hereditary neuropathy with liability to pressure palsy (hnpp)), multifocal acquired demyelinating sensory and motor neuropathy (madsam), neuropathy
MeSH terms: Case Reports

Hereditary neuropathy with liability to pressure palsy (HNPP) is a genetic condition in which individuals develop recurrent nerve palsies due to nerve injury at susceptible anatomic sites. Because of its rarity, other diseases usually appear high in the differential list when the clinical presentation is suggestive. Here, we describe a case of HNPP initially thought of as radiculopathy and focal chronic inflammatory demyelinating polyneuropathy (CIDP). Only on close clinical examination, supportive electrodiagnostic tests, and recurrence with typical history, a diagnosis of HNPP was suspected and later confirmed by a genetic test.
Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review
Authors: Hyma Polimera, Prashanth Moku, Shady Piedra Abusharar, Monali Vasekar, Jayakrishna Chintanaboina
Journal: Case Rep Oncol Med (2020)
MeSH terms: Case Reports

Ewing sarcoma (ES) is a highly aggressive malignant bone cancer. ES is part of the Ewing sarcoma family of tumors (ESFT), which express characteristic t(11;22) translocation as well as higher levels of CD99. Given that metastasis and tumor burden are significant prognostic factors in patient's response to treatment, prompt diagnosis is needed to effectively treat ESFT patients. However, the challenges in classifying and characterizing ESFT complicate effective management and treatment of ES. In this report, we present a rare case of ES metastasis to the pancreas. Upon review of the literature, we found 39 cases of ESFT involving the pancreas, but only 3 were metastatic to the pancreas while the remaining cases of ESFT primarily originated from the pancreas. Given the rarity of such metastasis, the positive outcome in our patient's case may explain the importance of prompt diagnosis in order to initiate appropriate treatment.