OpenMed/multicare-articles huggingface dataset:
Ovarian tissue cryopreservation for a 3-year-old girl with Mosaic Turner syndrome in China: First case report and literature review
Authors: Jiaojiao Cheng, Xiangyan Ruan, Juan Du, Fengyu Jin, Muqing Gu, Yurui Wu, Alfred O Mueck
Journal: Front Endocrinol (Lausanne) (2022)
Keywords: fertility preservation, follicle density, ovarian function, ovarian tissue cryopreservation, premature ovarian insufficiency, turner syndrome
MeSH terms: Turner Syndrome / complications, Case Reports, Review, Child, Child, Preschool, China, Humans

Background:
Although it cannot be predicted accurately which young females will develop premature ovarian insufficiency (POI) following chemotherapy or irradiation, patients at high risk of POI should be offered ovarian tissue cryopreservation (OTC). Our ovarian tissue cryobank is the first center in China. OTC was firstly performed on a 3-year-old girl with mosaic Turner syndrome (TS) in China. We report this case and present a literature review about TS girls' fertility preservation (FP).
Case presentation:
Karyotype analysis of umbilical cord blood showed that the girl was diagnosed with TS, 45,X [19]/46,XX [81]. The girl was a 3-year-old girl when her parents would like OTC to preserve fertility. No abnormality was found in the reproductive system, abdominal and cardiac ultrasound, spinal X-ray, and bone age. She was treated with growth hormone (GH) one year ago because of her short stature. GH has been discontinued now. Because of the high risk of POI, OTC was planned. The hormone level before OTC was FSH 4.27 IU/L, LH 0.00 IU/L, E2 < 11.80 pg/ml, AMH 1.06 ng/ml. Pelvic ultrasound showed that the size of the bilateral ovaries was 1.6 cm×0.7-0.8 cm, no enlarged follicles were found, and the maximum diameter of follicles was 0.2-0.37 cm. Ovarian tissue for OTC was taken from the whole right ovary by laparoscopic surgery, and the antral follicles could be seen in ovarian tissue preparation. Sixteen ovarian cortical slices were cryopreserved by slow freezing, with an average of 1380 follicles in round cortical tissue with a diameter of 2 mm, and the follicular density was about 440/mm3. The ovarian tissue from 10 children with non-TS was cryopreserved in our center, the median age was 5 (range 2-8) years old, and the median number of follicles was 766 (range 163-2250) per 2 mm biopsy. The follicles number in this girl were within normal range.
Conclusion:
TS patients should be evaluated early in childhood to benefit from FP. For highly selected young females with mosaic TS, if the endocrine evaluation does not indicate POI and other health problems do not rule out future pregnancy, it seems reasonable to consider OTC as an FP option.
Gait Analysis before and after Gastrocnemius Fascia Lengthening for Spastic Equinus Foot Deformity in a 10-Year-Old Diplegic Child
Authors: Manuela Galli, Veronica Cimolin, Giorgio Cesare Santambrogio, Marcello Crivellini, Giorgio Albertini
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

Purpose. This case study quantified kinematic and kinetic effects of gastrocnemius lengthening on gait in a Cerebral Palsy child with equinus foot. Methods. A 10-year-old diplegic child with Cerebral Palsy was evaluated with Gait Analysis (GA) before and after gastrocnemius fascia lengthening, investigating the lower limb joints kinematics and kinetics. Results. Kinematics improved at the level of distal joints, which are directly associated to gastrocnemius, and also at the proximal joint (like hip); improvements were found in ankle kinetics, too. Conclusions. This case study highlighted that GA was effective not only to quantify the results of the treatment but also to help preoperative decision making in dealing with CP child.
Intranodal Lymphangiography during Surgical Repair of Pelvic Lymphorrhea after Radical Cystectomy
Authors: Yasuyuki Onishi, Yusaku Moribata, Hironori Shimizu, Kosuke Shimizu, Takeshi Sano, Takashi Kobayashi, Yuji Nakamoto
Journal: Case Rep Urol (2021)
MeSH terms: Case Reports

Lymphorrhea can develop after various types of surgeries. Surgical closure of the lymphatic leakage point is an effective treatment option. However, it is difficult to identify the leakage point sometimes. Here, we report a case of pelvic lymphorrhea after radical cystectomy for bladder cancer. Identification of the leakage point was difficult during laparoscopic surgical repair of lymphorrhea. Intranodal lymphangiography was performed via the inguinal lymph node by injection of lipiodol, followed by injection of indigo carmine. Laparoscopy revealed extravasation of lipiodol and indigo carmine from the pelvic wall. The leakage point was successfully cauterized using an electric scalpel. Lymphorrhea improved after the surgical repair. This case suggests that intranodal lymphangiography may be useful for detecting the site of lymphatic leakage during the surgical repair of lymphorrhea.
Case Report of Spontaneous Bilateral Ovarian Pregnancy in a Nulliparous Lady
Authors: Abdulrahman D Mahroofi, Jawaher K Alsaqer, Nawal Saad Alabdulla, Rihab Ismael, Stephanie Hsu, M Samy Ismail
Journal: Case Rep Obstet Gynecol (2021)
MeSH terms: Case Reports

Nontubal ectopic pregnancies, especially ovarian ones, are rare. Here, we report a case of spontaneous bilateral ovarian pregnancy in a 23-year-old nulliparous lady who presented with a three-day history of abdominal pain localized to the right iliac fossa. Laboratory investigations and pelvic US and transvaginal US findings were suggestive of a right ovarian ectopic pregnancy and left ovarian cyst. Following the patient's consent, the gynaecologist laparoscopically removed the right ovarian ectopic pregnancy and performed a left ovarian cystectomy. Histopathology revealed findings of trophoblastic tissue and chorionic villi with products of conception in both ovaries leading to the diagnosis of bilateral spontaneous ectopic pregnancy. Physicians must be mindful in cases that have a similar clinical presentation because an early diagnosis leads to a reduction in the morbidity and mortality of this specific patient population and helps to improve their overall prognosis.
Modafinil in the rehabilitation of a patient with post-surgical posterior fossa syndrome: a lesson to be learned?
Authors: Emanuela Molinari, Maria Oto, Ashita Waterston, Natasha Fullerton
Journal: Cerebellum Ataxias (2019)
Keywords: cerebellar mutism syndrome, modafinil, behavioral, posterior fossa syndrome
MeSH terms: Review

Disorders of the cerebellum may present with motor, cognitive, behavioral and affective symptoms. There is a growing interest in developing neuroanatomical models of symptoms generation that involve the cerebellum and the cerebello-cortical connections. We describe an exciting first case report of successful use of Modafinil in an adult patient with post-operative posterior fossa syndrome. Following resection of a melanoma metastasis in the cerebellum the patient developed striking affective and behavioral symptoms in the form of withdrawn flat mood and disengagement. This neurobehavioral presentation severely impacted on his quality of life, independence, and ability to engage in the neuro-rehabilitative program. Pharmacological treatment with Modafinil ameliorated these emotional and behavioral aspects, and also fatigue. Treatment with Modafinil hence affected recovery and outcome for the patient. To our knowledge, this is the first description of a successful pharmacological intervention in an adult with post-surgical posterior fossa syndrome and negative neurobehavioral presentation. Our findings illustrate the variability of the presentation of post-operative posterior fossa syndrome in adults, and the importance of delivering targeted treatment to maximize the benefits of neurorehabilitation. The manuscript highlights the following points: 1. post-operative consequences currently under the wide umbrella of posterior fossa syndrome, can indeed manifest in adults; 2. a wide spectrum of neurobehavioral symptoms can occur, including a presentation with predominantly negative features; 3. the type of neurobehavioral presentation should guide the treatment choice with particular consideration of drugs that potentially modulate the cerebello-frontal connections; 4. Modafinil can be a candidate for effective treatment in presentations with predominantly negative behavioral symptoms.
Episcleritis Related to Drug-Induced Lupus Erythematosus following Infliximab Therapy: A Case Report
Authors: Irini P Chatziralli, Evgenia Kanonidou, Alexandros Chatzirallis, Prodromos Dimitriadis, Petros Keryttopoulos
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

Drug-induced lupus erythematosus is defined as a lupus-like syndrome temporally related to continuous drug exposure which resolves after discontinuation of the offending drug. Herein, we describe a patient with distinct clinical manifestations of anti-TNF-associated DILE related to infliximab therapy. The patient exhibited clinical and laboratory findings of lupus-like illnesses as well as ocular disorders, such as episcleritis. The main message is that the symptoms of DILE should not be overlooked, although sometimes other systematic conditions may underlie them. As a result, it is very important for the clinicians to evaluate the symptoms of DILE and manage appropriately these cases.
Multiple jejunal perforation secondary to intestinal tuberculosis infection: a case report
Authors: Anthony Lyonga Ngonge, Domin Sone Majunda Ekaney, Carlson-Babila Sama, Joffi Musonge-Effoe, Valery Sammah Effoe, Gerald Ekwen
Journal: Pan Afr Med J (2017)
Keywords: abdominal tuberculosis, hiv infection, intestinal perforation
MeSH terms: Abdomen, Acute / diagnosis, HIV Infections / complications, Intestinal Perforation / diagnosis, Tuberculosis, Gastrointestinal / diagnosis, Case Reports, Abdomen, Acute / microbiology, Adult, CD4 Lymphocyte Count, Coinfection, Diagnosis, Differential, Female, Humans, Intestinal Perforation / etiology, Intestinal Perforation / surgery, Laparotomy / methods, Tuberculosis, Gastrointestinal / complications

Abdominal tuberculosis (TB) may affect any part of the gastrointestinal tract resulting in significant morbidity and mortality. There is an increase in the incidence of abdominal TB favored by the emergence of multi-drug resistant Mycobacterium tuberculosis and immunosuppression especially from HIV co-infection. Our case is that of a 31 year old HIV-positive woman, adherent to antiretroviral therapy, who presented with a 2 month history of progressive abdominal distention, drenching night sweat and fatigue, but without fever. She was admitted on a presumptive diagnosis of peritoneal TB, and suddenly developed signs and symptoms of an acute abdomen. Laboratory investigations showed a CD4+ count of 155 cells/µL, white blood cell count of 15,700 cells/mm3 and haemoglobin of 8.0g/dl. An emergency laparotomy revealed small bowel caseous necrosis with multiple jejunal perforations. Ziehl-Nelsen staining of operative specimen was positive for acid fast bacilli. Given her immunodeficiency status, clinical signs and symptoms, CD4 cell count > 50 cells/µL, and intestinal sample showing caseous necrosis and perforations, a final diagnosis of intestinal TB was made. In conclusion, abdominal tuberculosis may mimic a number of intra-abdominal pathologies; thus should always be considered as a differential diagnosis in patients presenting with acute abdomen in TB-endemic areas especially in an HIV-positive individual.
Non postoperative biloma in Mauritania: case report and literature review
Authors: Ahmedou Moulaye Idriss, Yahya Tfeil, Jiddou Sidi Baba, Ahmedou Mohamed Abdallahi, Ahmed Bezeid
Journal: Pan Afr Med J (2018)
Keywords: biloma, ct-scan, cholelithiasis, drainage, fluid collection, imaging
MeSH terms: Abdominal Pain / etiology, Bile / diagnostic imaging, Drainage / methods, Case Reports, Review, Acute Pain / etiology, Aged, Female, Humans, Mauritania, Tomography, X-Ray Computed / methods, Ultrasonography / methods

Biloma is used to describe abnormal accumulation of bile outside biliary tract. It is a very rare condition with extrahepatic diffused or encapsulated collection of bile, mostly post-operative or post traumatic. A 72-year-old woman was referred to our hospital with acute abdominal pain located in right upper quadrant. Clinical examination suspected abdominal collection. Imagery (ultrasound and computed tomography scan) demonstrated a large well-defined intra-abdominal collection. Percutaneous ultrasound guided drainage of abdominal collection revealed a bile fluid. Drain was removed a week later and complete resolution of symptoms was obtained in two weeks. Even in the absence of specific diagnostic indications, radiological images may play a key role in the evaluation of suspected biloma in patients with appropriate medical history and clinical characteristics.
Importance of Imaging in Congenital Unilateral Vocal Fold Paralysis: A Case of Neck Neuroblastoma Presenting with Unilateral Vocal Fold Paralysis
Authors: W X Yeo, C Y Chan, K K H Tan
Journal: Case Rep Otolaryngol (2021)
MeSH terms: Case Reports

Congenital vocal fold paralysis (VFP) is an important cause of respiratory compromise in infants. It can either be unilateral or bilateral, while imaging is routinely performed for bilateral VFP to evaluate for potential neurological causes, and such a practice may not be routine for unilateral VFP. While many of the unilateral VFP cases are idiopathic, the cause may occasionally be more sinister in nature, such as tumors. Therefore, unless an obvious cause of unilateral VFP is present (such as cardiac surgery or birth trauma), routine imaging of the brain, neck, and mediastinum should be performed for congenital unilateral VFP. We describe a rare case of a cervical neuroblastoma presenting with unilateral VFP that was detected only on imaging, thus highlighting its value and importance.
Long-Term Use of a Sensory Prosthesis Improves Function in a Patient With Peripheral Neuropathy: A Case Report
Authors: Diane M Wrisley, Gillian McLean, Jennifer Baity Hill, Lars I E Oddsson
Journal: Front Neurol (2021)
Keywords: balance, case report, diabetes, fall risk, gait, neuroprosthesis, peripheral neuropathy, sensory substitution
MeSH terms: Case Reports

Background: Peripheral neuropathy (PN) can result in either partial or complete loss of distal sensation resulting in an increased fall risk. Walkasins® uses a shoe insert to detect the magnitude and direction of sway and sends signals to a leg unit that provides sensory balance cues. The objective of this case report is to describe the long-term influence of the Walkasins® lower limb sensory neuroprosthesis on balance and gait for an individual with diabetic PN. Case Description: A 51-year-old male with a 3-year history of PN and a 10-year history of type II diabetes mellitus was fitted bilaterally with Walkasins® and utilized them 8-10 hours/day for more than 2 years. Although, vibration and tactile sensation thresholds were severely impaired at his 1st metatarsophalangeal joint and the lateral malleolus bilaterally he could perceive tactile stimuli from the Walkasins® above the ankles. Outcomes: Following Walkasins® use, his Activities-specific Balance Confidence Scale (ABC) scores improved from 33 to 80%. His mean Vestibular Activities of Daily Living (VADL) scores decreased from 3.54 to 1. His Functional Gait Assessment (FGA) scores increased from 13/30 to 28/30 and his miniBESTest scores improved from 15/28 to 26/28. Gait speed increased from 0.23 to 1.5 m/s. The patient described a decrease in pain and cramping throughout his lower extremities and an increase in function. Discussion: Gait and balance improved with the use of the Walkasins® and participation in a wellness program. This improvement suggests that the use of sensory substitution devices, such as the Walkasins®, may replace sensory deficits related to gait and balance dysfunction experienced by patients with PN. Further research is needed to determine if other patients will have a similar response and what the necessary threshold of sensory function is to benefit from use of the Walkasins®.
Case report: An overlooked complication of the dural suture after craniotomy: pseudoaneurysm of the middle meningeal artery with endovascular resolution
Authors: Yao Xu, Xiangdong Li
Journal: Front Neurol (2023)
Keywords: aneurysm, case report, cerebral angiography, craniofacial surgery, middle meningeal artery (mma)
MeSH terms: Case Reports

Aneurysms of the middle meningeal artery (MMA) are exceedingly uncommon and mainly result from traumatic brain damage, but this report describes a case of MMA aneurysm induced by cranial surgery. Surgery was performed on a 34-year-old male with cerebrovascular malformation and cerebral hemorrhage. Cerebral angiography revealed no MMA aneurysm before craniocerebral surgery; however, a postoperative angiogram revealed a new MMA aneurysm. Aneurysms of the MMA are uncommon consequences of brain surgery. Based on our findings, the MMA as well as other meningeal arteries should be avoided while suturing the dura mater tent to prevent aneurysms.
Restoration of a Nonvital Tooth with Fiber Reinforce Composite (Wallpapering Technique)
Authors: Sara Valizadeh, Ladan Ranjbar Omrani, Simone Deliperi, Farzaneh Sadeghi Mahounak
Journal: Case Rep Dent (2020)
MeSH terms: Case Reports

Introduction:
Reconstruction of endodontically treated tooth (ETT) is one of the greatest challenges in dentistry. Clinical success of fiber reinforcement composite (FRC) restorations in ETT depends on many factors like remaining tooth structure, knowing advantages of adhesive dentistry besides its drawbacks, and the correct use of fibers in combination with resin composite. Case Report. This article presents a case in which fibers have been used in composite buildup in order to increase the toughness and strength of the ETT direct restoration. In addition, this technique does not require root canal enlargement to eliminate the risk of root perforation. Also, this one visit treatment can be helpful for patients that could not pay the cost of indirect restoration and/or have no time.
Conclusion:
It seems in selected patients with special considerations, FRC composite restoration is valid alternatives for indirect restoration.
Free-Floating Scapular Spine: A Rare Shoulder Injury
Authors: John H Cabot, Khang H Dang, Anil K Dutta
Journal: Case Rep Orthop (2019)
MeSH terms: Case Reports

A specific treatment protocol for managing scapular spine fractures does not currently exist. The purpose of our report is to describe this type of injury and detail our treatment management in order to better elucidate this rare pathology. We present a case of a 26-year-old female with an acute scapular spine and base fracture after a motor vehicle collision. Successful treatment of an acute free-floating scapular spine fracture was achieved with open reduction and internal fixation utilizing an elbow plate. Since scapular spine fractures are an unfortunate, rare injury, it may impose difficult challenges to the treating surgeon. With our case report, we hope to contribute to the overall knowledge of scapular spine fractures and offer our experience with a successful and appropriate treatment option in our patient.
Urinoma: Prompt Diagnosis and Treatment Can Prevent Abscess Formation, Hydronephrosis, and a Progressive Loss of Renal Function
Authors: Jason Goldwasser, Razwana Wahdat, James Espinosa, Alan Lucerna
Journal: Case Rep Emerg Med (2018)
MeSH terms: Case Reports

This case describes a 70-year-old female who presented with right flank pain around the site where a stent had been placed in her right kidney at an outside hospital several months earlier. The patient arrived tachycardic with a leukocytosis and a lactic acidosis. Further imaging revealed a very hydronephrotic right kidney and an extremely large fluid collection in the right retroperitoneum extending into the right flank consistent with leakage of urine from the obstructed right kidney. Prompt treatment of this rare phenomenon is crucial for delay in medical care can lead to abscess, hydronephrosis, electrolyte instability, and a progressive loss of renal function. Treatment for small urinomas is usually conservative as the collection will most often be reabsorbed. Larger urinomas even without systemic signs often necessitate more aggressive medical treatment. A drainage catheter can be placed with ultrasound or CT guidance. Percutaneous nephrostomy tubes are often used as well for additional drainage and decompression. Fluid culture is recommended to guide antibiotic treatment.
Sterile necrotizing and non-necrotizing granulomas in a heart transplant patient with history of PTLD: A unique finding
Authors: Nicholas Piening, Saxena Saurabh, Armando Salim Munoz Abraham, Hector Osei, Colleen Fitzpatrick, Jose Greenspon
Journal: Int J Surg Case Rep (2019)
Keywords: case report, general surgery, pediatric surgery, posttransplant lymphoproliferative disease, transplant surgery

Introduction:
Posttransplant lymphoproliferative disease (PTLD) is a known complication in patients with solid organ transplant. It can present as localized or disseminated tumor. The cornerstone of management consists of reduced immunosuppression (RI). In select cases, localized disease can potentially be curative with surgical excision.
Presentation of case:
Here we present a case of a 19-year-old female with orthotopic heart transplant with two episodes of recurrent PTLD. After the second episode she was found to have asymptomatic splenic lesions which were refractory to RI and chemotherapy. She subsequently underwent splenectomy that showed sterile necrotizing and non-necrotizing granulomas with no evidence of PTLD.
Discussion:
Based on our literature search this is the first ever reported case of sterile granulomas in a patient with recurrent PTLD which could potentially be diagnosed with minimally invasive biopsy rather than diagnostic splenectomy.
Conclusion:
This report is an attempt to create awareness regarding potential for presence of sterile granulomas in patients with recurrent PTLD and discuss the use of percutaneous biopsy before splenectomy.
The clinical utility of serum free light chain and heavy/light chain assays in monitoring disease activity in patients with IgG myeloma after achieving a deep response
Authors: Kazuyuki Shimizu, Yoshikazu Kamiya, Junji Itoh, Jun Okada, Merrell Lim, Satoru Sugiyama
Journal: Clin Case Rep (2017)
Keywords: deep response, disease monitoring, involved/uninvolved hlc ratio, multiple myeloma, serum heavy/light chain (hlc) assay
MeSH terms: Case Reports

Heavy/light chain (HLC) assay will enable us to evaluate the changes in the concentrations of iHLC and uHLC separately and to better identify whether the change observed is clonal or reactive. It would therefore aid in decision making for earlier implementation or discontinuation of treatment for patients with intact immunoglobulin multiple myeloma (MM).
Utilization of Liposuction for Delayed Morel-Lavallée Lesion: A Case Report and Review
Authors: Preston Gardner, Diana Flis, Kongkrit Chaiyasate
Journal: Case Rep Surg (2017)
MeSH terms: Case Reports

Morel-Lavallée lesions are irregularly occurring and often overlooked results of traumatic injuries, resulting in potential long-term encapsulation of fluid between soft-tissue layers. The objective in this review was to discuss the delayed presentation of a Morel-Lavallée lesion and operative utility of liposuction in the patient's treatment and review literature with particular focus on diagnosis and therapeutic interventions. The reviewed case demonstrates the presentation and successful therapy of a young female presenting with a MLL and contour deformity.