OpenMed/multicare-articles huggingface dataset:
Case report: Single-session double-Ilizarov lengthening technique in the treatment of a child with congenital fibular deficiency
Authors: Wen Shu, Changjie Yue, Haobo Zhong, Xin Tang
Journal: Front Pediatr (2022)
Keywords: child, congenital fibular deficiency, double-ilizarov lengthening technique, ipsilateral, single session
MeSH terms: Case Reports

Background:
Congenital fibular deficiency is a rare disease with a broad spectrum of deformities. Associated anomalies complicate the symptoms of patients and, consequently, individualized treatments that aim at normal function and acceptable appearance.
Case presentation:
We present a case of congenital femoral and fibular shortening in the right lower limb with foot anomaly at school age. The patient underwent limb lengthening procedure in a single session on the right femur and tibia at the same time using a double-Ilizarov frame. The functional and cosmetic of his right lower extremity achieved a good outcome. Complications were minimal except for the superficial infection. Treatment lasted for 9.2 months, allowing for returning the patient to functional activity as soon as possible.
Conclusion:
A satisfactory result was obtained with limb lengthening in a single session using double Ilizarov external fixators in a school-aged patient with congenital fibular deficiency.
Posterior Reversible Encephalopathy Syndrome Presenting with Atypical Findings: Report of Two Cases
Authors: Paolo Cerrone, Patrizia Sucapane, Rocco Totaro, Simona Sacco, Antonio Carolei, Carmine Marini
Journal: Case Rep Neurol Med (2018)
MeSH terms: Case Reports

Background:
Posterior reversible encephalopathy syndrome (PRES) is characterized by a variable association of symptoms including headache, consciousness impairment, visual disturbances, seizures, and focal neurological signs. Treating the underlying cause usually leads to partial or complete resolution of symptoms within days or weeks. Brain MRI findings include hyperintensities on T2-weighted sequences and their reversibility on follow-up exams. We describe two patients, one with an atypical clinical presentation characterized by a severe and prolonged impairment of consciousness and the other with atypical neuroimaging findings.
Case presentation:
The first patient was a 42-year-old woman, with a negative medical history, presenting with seizures, lethargy, and left hemiparesis, 60 hours after uncomplicated delivery. Brain MRI showed an atypical pattern of alterations, with patchy asymmetric distribution in all lobes. Symptoms completely resolved after twelve days. The second patient was a 59-year-old woman with a history of hypertension, presenting with severe impairment of consciousness, vision loss, and seizures. Symptoms partially resolved after three weeks.
Conclusion:
PRES is characterized by reversible symptoms and radiological findings. Brain MRI usually shows widespread oedema in white matter with typical patterns. The cases we described suggest that PRES may presents with atypical symptoms and radiological manifestations, mimicking other neurological conditions.
Articaine as an alternative in lidocaine allergy: Case report of a seventy year old male patient
Authors: Mansi Dey, Bibhu Prasad Mishra, Deepti Awasthi, Abhijeeta Sahoo
Journal: Int J Surg Case Rep (2020)
Keywords: allergy, articaine, lidocaine, skin prick testing (spt)
MeSH terms: Case Reports

Introduction:
Allergy to lidocaine is extremely rare but if it occurs, one should switch to an alternative drug and discontinue the use of lidocaine so that adverse consequences do not occur.
Presentation of case:
We present the case of a 70 year old male patient who had come to our department to undergo extraction of his decayed teeth under local anesthesia.
Discussion:
He had history of allergy to lidocaine. Type IV hypersensitivity to lidocaine was confirmed by positive skin prick testing to the drug. Skin prick testing was also performed for articaine that was available with us, and the test was found to be negative without any wheal or flare reaction even after 72 h. Thus it was confirmed that he was non-allergic to articaine and successfully underwent exodontia by using the same.
Conclusion:
Articaine can be a suitable alternative in patients with true lignocaine allergy and vice-versa. No cross-reactivity has been reported between lidocaine and articaine so far. However, the number of cases reported in the past are limited, hence more cases are required in the future to prove its authenticity.
Pityriasis Versicolor Resistant to Antifungal Drugs in a Patient in Lomé (Togo)
Authors: Julienne Teclessou, Koussake Kombate, Bayaki Saka, Séfako Abla Akakpo, Palokinam Pitche
Journal: Case Rep Dermatol Med (2022)
MeSH terms: Case Reports

Background:
Pityriasis versicolor (PV) is a ubiquitous superficial skin mycosis that often affects young adults. It is often effectively treated with local or oral antifungal agents. Cases of PV resistance to antifungal agents have been reported rarely. We report a case of antifungal resistant PV. Observation. A 22-year-old patient was followed since the age of 17 years in a dermatology outpatient clinic for hyperpigmented scaly macular lesions of the trunk and upper limbs. The clinical diagnosis of PV was retained. The patient was treated by fluconazole 300 mg/week before being lost to follow-up. He was seen again in 2019 (about 2 years later) for the same symptomatology and treated again by fluconazole and ciclopirox olamine cream without improvement. He was again lost to follow-up and seen again six months later. A mycological sample was taken and Aspergillus niger was isolated. The patient was treated by itraconazole for 6 weeks. The evolution was marked by a clinical status quo. The patient was again put on salicylated petroleum jelly 10% associated with terbinafine cream and then lost to follow-up.
Conclusion:
The emergence of fungal resistance to antifungal drugs does not spare PV. It can therefore be resistant to several antifungal drugs, leaving clinicians and patients in despair.
Rhabdomyolysis: An Unusual Presentation of Mycoplasma pneumoniae Infection in an Adult-A Case Report and Literature Review
Authors: Jaspreet Kaler, Osama Mukhtar, Bilal Khan, Binav Shrestha, Ravinder Kaler, Brandon Ting, Mazin Khalid
Journal: Case Rep Med (2018)
MeSH terms: Case Reports

Mycoplasma pneumoniae is a common cause of community-acquired pneumonia, and many extrapulmonary manifestations have been described, but rhabdomyolysis is infrequently reported in adults. Of the few cases that have been reported in adults, it was almost exclusively seen when pneumonia was present. We report a case of a 30-year-old male who came in with complaints of fever and myalgia for three days. Immunoglobulin M antibodies for Mycoplasma pneumoniae were positive and trending up, despite having no radiographic evidence of pneumonia on chest X-ray or CT scan. He was treated successfully with levofloxacin and intravenous hydration. Later, his condition was clinically and biochemically improved, and he was discharged. Our patient did not present with typical respiratory tract symptoms of a mycoplasma infection. In addition, there was an absence of pneumonia on imaging, suggesting that rhabdomyolysis secondary to mycoplasma might be underdiagnosed and go untreated in the setting of low clinical suspicion. Upon review of the literature, there is only one other case of mycoplasma infection where rhabdomyolysis occurred in the absence of pneumonia. However, the degree of rhabdomyolysis in our case was much more severe. Although rare, when faced with rhabdomyolysis, Mycoplasma pneumoniae should be kept as a differential diagnosis even in the absence of pneumonia on radiological imaging.
Metastasis of colorectal adenocarcinoma to the right ventricle in a young man: a case report
Authors: Ahmed Badheeb, Faisal Ahmed, Yahya Alhosni, Mohamed Badheeb, Hamoud Obied, Islam Seada
Journal: Pan Afr Med J (2023)
Keywords: cardiac metastasis, case report, colorectal cancer, right ventricle
MeSH terms: Adenocarcinoma / pathology, Colonic Neoplasms / pathology, Colorectal Neoplasms / pathology, Case Reports, Antineoplastic Combined Chemotherapy Protocols / therapeutic use, Bevacizumab / therapeutic use, Heart Ventricles / diagnostic imaging, Heart Ventricles / pathology, Humans, Male, Neoplasm Metastasis, Bevacizumab

Cardiac cancers are exceedingly rare, mainly appearing as secondary cancers in patients with numerous systemic metastases, and are often detected by autopsies. Right ventricle (RV) metastasis from metastatic colorectal cancer (mCRC) is rarely reported in the literature. We report a 24-year-old man's case of mCRC, who developed positional variation in pulse rate while receiving the second cycle of chemotherapy. The echocardiography and chest computed tomography (CT) scan showed RV mass. The tumor was right-sided, and Kirsten rat sarcoma (KRAS) mutated based on that. He was treated with FOLFOX chemotherapy protocol plus bevacizumab and enoxaparin with an initial reduction in mass size. However, follow-up CT 9 months later demonstrated disease progression. For that, the chemotherapy was stopped, and the patient received palliative care. In conclusion, this case provides evidence that mCRC and RV location of metastasis can and do occur. In such a case, therapeutic intervention should be determined by weighing the benefits and risks.
ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination
Authors: Shiko Gen, Takanori Iwai, Sayuri Ohnari, Kanako Nobe, Naofumi Ikeda
Journal: Case Rep Nephrol (2023)
MeSH terms: Case Reports

We experienced a case of myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis after Moderna COVID-19 vaccination. An 82-year-old woman developed pyrexia and general malaise one month after her third booster vaccine, and the symptoms persisted. Blood testing revealed inflammation, a high level of MPO-ANCA, and microscopic hematuria. MPO-ANCA-associated vasculitis was diagnosed by renal biopsy. The symptoms improved with steroid therapy. Common adverse reactions to mRNA vaccines against COVID-19 include pyrexia and general malaise, but MPO-ANCA-associated vasculitis can also occur. If pyrexia, prolonged general malaise, urinary occult blood, or renal impairment is observed, the onset of MPO-ANCA-associated vasculitis should be considered.
Primary malignant melanoma of the gallbladder: a case report and review of the literature
Authors: Mehmet Fatih Haskaraca, Mustafa Ozsoy, Ismail Ozsan, Kamile Kurt
Journal: Case Rep Surg (2012)

Malignant melanoma is characterized by the ability of diffuse metastases. Since the first report of an isolated malignant melanoma case of the gallbladder, it is already controversial whether isolated cases are metastatic or primary tumors. A 49-year-old woman appealed to the emergency unit because of abdominal pain. Ultrasonography revealed increased thickness of the gallbladder wall and a lesion with surrounding fluid sized 12 mm without acoustic shadow, which arose from the gallbladder wall and was consistent with a polyp. Histopathologic evaluation of the surgical specimen after laparoscopic cholecystectomy revealed malign epithelial tumor consisting of atypical cells with large eosinophilic cytoplasm and dense melanin pigment within the cytoplasm of the tumor cells. As no other focus was identified as a result of the evaluation, the patient was diagnosed with primary malignant melanoma of the gallbladder. In this paper, we aimed to define our treatment modality for a case with isolated malignant melanoma of the gallbladder.
Contribution of cognitive and bodily navigation cues to egocentric and allocentric spatial memory in hallucinations due to Parkinson's disease: A case report
Authors: Cosimo Tuena, Giuseppe Riva, Immacolata Murru, Luca Campana, Karine M Goulene, Elisa Pedroli, Marco Stramba-Badiale
Journal: Front Behav Neurosci (2022)
Keywords: lewy bodies, embodiment, psychosis, spatial navigation, virtual reality
MeSH terms: Case Reports

Parkinson's disease (PD) manifestations can include visual hallucinations and illusions. Recent findings suggest that the coherent integration of bodily information within an egocentric representation could play a crucial role in these phenomena. Egocentric processing is a key aspect of spatial navigation and is supported by the striatum. Due to the deterioration of the striatal and motor systems, PD mainly impairs the egocentric rather than the allocentric spatial frame of reference. However, it is still unclear the interplay between spatial cognition and PD hallucinations and how different navigation mechanisms can influence such spatial frames of reference. We report the case of A.A., a patient that suffers from PD with frequent episodes of visual hallucinations and illusions. We used a virtual reality (VR) navigation task to assess egocentric and allocentric spatial memory under five navigation conditions (passive, immersive, map, path decision, and attentive cues) in A.A. and a PD control group without psychosis. In general, A.A. exhibited a statistically significant classical dissociation between the egocentric and allocentric performance with a greater deficit for the former. In particular, the dissociation was statistically significant in the "passive" and "attentive cues" conditions. Interestingly in the "immersive" condition, the dissociation was not significant and, in contrast to the other conditions, trends showed better performance for egocentric than allocentric memory. Within the theories of embodiment, we suggest that body-based information, as assessed with VR navigation tasks, could play an important role in PD hallucinations. In addition, the possible neural underpinnings and the usefulness of VR are discussed.
A rare case of pulmonary tuberculosis with simultaneous pulmonary and skin sarcoidosis: a case report
Authors: Kornelija Mise, Ivana Goic-Barisic, Neira Puizina-Ivic, Igor Barisic, Marija Tonkic, Irena Peric
Journal: Cases J (2010)

Background:
Tuberculosis and sarcoidosis are chronic diseases that rarely occur concomitantly. Sarcoidosis is a multisystem granulomatous disorder characterized pathologically by the presence of non-caseating granulomas in involved tissues. Tuberculosis is infectious disease caused by Mycobacterium tuberculosis characterized by granulomas with caseous necrosis.
Case presentation:
We present a case of 43-year-old female refugee from Kosovo with microbiological confirmation of pulmonary tuberculosis and pulmonary and skin sarcoidosis at the same time. Three weeks after corticosteroid therapy for pulmonary sarcoidosis was introduced, positive finding of mycobacterium culture of bronchial aspirate was observed. Based on these results, corticosteroid therapy was excluded and antituberculous therapy was introduced for six months. In the meantime, new nodes on face and nose appeared and skin sarcoidosis was diagnosed. The patient was given corticosteroids and colchicine according to the skin and pulmonary sarcoidosis therapy recommendation.
Conclusion:
The authors of this study suggest that in cases when there is a dilemma in diagnosis between tuberculosis and sarcoidosis we should advance with corticosteroid therapy until we have microbiological confirmation of mycobacterium culture. This case is remarkable because this is a third described case of sarcoidosis and tuberculosis together (the first reported in Asia, the second in South Africa), and to authors knowledge, this is a first case report in Europe.
A case report of urinary bladder carcinosarcoma and review of the literature
Authors: Christos Zachariadis, Ioannis Efthimiou, Stylianos Giannakopoulos, Athanasios Bantis, Alexandra Giatromanolaki, Efthimios Sivridis, Stavros Touloupidis
Journal: Case Rep Urol (2011)
MeSH terms: Case Reports

Carcinosarcoma of the bladder is an unusual tumour characterized by a combination of malignant epithelial and soft tissue elements. Most of the reported cases have been case reports or small series. Optimal treatment is uncertain. We herein report our experience in such a case treated with transurethral resection followed by radiotherapy with adverse final outcome. Treatment of bladder carcinosarcomas should be aggressive and multimodal but optional treatment is still unknown. Radiotherapy alone is insufficient as a treatment option of these aggressive tumors.
Primary obstructive megaureter with giant ureteral stone: a case report
Authors: Abdullah Demirtaş, Nurettin Sahin, Emre Can Akınsal, Oguz Ekmekçioğlu, Atila Tatlışen
Journal: Case Rep Urol (2013)

A 19-year-old male patient was admitted with flank pain, which had lasted intermittently for four years. In X-ray, there was a radiopacity with a dimension of 6 × 4 cm on the left pelvic bone. Intravenous pyelography revealed a huge left megaureter with a stone in the lower end and grade V hydronephrosis. A left ureterolithotomy, left nipple ureteroneocystostomy, and psoas hitch operation was performed. A voiding cystourethrogram taken three months after the operation showed no reflux, and in IVP there was reduced dilatation of the collecting system when compared to the ureter before the operation.
Rapidly fatal hemorrhagic pneumonia and group A Streptococcus serotype M1
Authors: Maria Santagati, Teresa Spanu, Marina Scillato, Rosaria Santangelo, Fabio Cavallaro, Vincenzo Arena, Giacomo Castiglione, Marco Falcone, Mario Venditti, Stefania Stefani
Journal: Emerg Infect Dis (2014)
MeSH terms: Hemorrhage, Pneumonia, Bacterial / microbiology, Pneumonia, Bacterial / pathology, Streptococcus pyogenes / classification, Case Reports, Research Support, Non-U.S. Gov't, Adult, Aged, Autopsy, Fatal Outcome, Female, Humans, Lung / microbiology, Lung / pathology, Male, Multilocus Sequence Typing, Pneumonia, Bacterial / diagnosis, Streptococcus pyogenes / genetics, Tomography, X-Ray Computed

We report 3 cases of fulminant hemorrhagic pneumonia in previously health patients. Sudden-onset hemoptysis and dyspnea developed; all 3 patients and died <12 h later of massive pulmonary bleeding, despite aggressive supportive care. Postmortem analysis showed that the illnesses were caused by group A Streptococcus emm1/sequence type 28 strains.
Haemoptysis secondary to a complicated hydatid cyst of the lung: A case report
Authors: R Manganyi, A Moodley, T Pennel, C Ofoegbu, A Linegar
Journal: Afr J Thorac Crit Care Med (2020)
Keywords: noonan syndrome, bronchial artery, haemoptysis, polyps
MeSH terms: Case Reports

Pulmonary hydatid disease is almost exclusively caused by the infestation of the larval stage of Echinococcus granulosus. Humans are infected, accidentally, through the faeco-oral route by the ingestion of food and milk, contaminated by dog faeces containing the ova of parasites or direct contact with dogs. We describe an unusual cause of massive haemoptysis in a young male who had bilateral lung hydatid cysts as well as a large splenic hydatic cyst. He underwent bilateral thoracotomies for cyst excision for relief of haemoptysis.
Coexisting pulmonary tuberculosis and mucormycosis in a patient with aplastic anemia post allogenic stem cell transplantation
Authors: Sanjeev Kumar Sharma, Narendra Agarwal, Anjan Mukherjee, Tulika Seth, Pravas Mishra, Immaculata Xess, Manoranjan Mahapatra, Sanjay Sharma
Journal: Mediterr J Hematol Infect Dis (2011)
MeSH terms: Case Reports

Infections are the most common cause of morbidity and mortality in allogenic stem cell transplant recipients. Survival of the patient depends on the accurate diagnosis of the infectious agents and prompt and effective management of the infection alongwith maintenance of adequate immunosuppression post transplantation. We here reported a case of aplastic anemia who developed left upper lobe consolidation post allogenic stem cell transplantation and was found to have combined infection with tuberculosis and mucormycosis. This is the first case of combined infection with tuberculosis and mucormycosis reported in such a host, with a favourable outcome.
Spontaneous Pneumomediastinum in Labor
Authors: Mohamed Adnane Berdai, Said Benlamkadem, Smael Labib, Mustapha Harandou
Journal: Case Rep Obstet Gynecol (2017)
MeSH terms: Case Reports

Spontaneous pneumomediastinum and subcutaneous emphysema also known as Hamman's syndrome is a very rare complication of labor that is often related to the valsalva maneuver during the labor. In most case, Hamman's syndrome is a self-limiting condition, rarely complicated unless there are underlying respiratory diseases. Chest X-ray can be a useful early diagnostic technique in severe clinical presentation. We report an uneventful pregnancy in a primigravid parturient, which was complicated in the late second stage of labor by the development of subcutaneous emphysema, pneumomediastinum, and mild pneumothorax. Spontaneous recovery occurred after four days of conservative management. This condition shows the major interest of labor analgesia especially locoregional techniques.
Orofacial manifestations of mucocutaneous leishmaniasis: a case series from Brazil
Authors: Gleicy Gabriela Vitória Spinola Carneiro Falcão, Liliane Lins-Kusterer, Patricia Miranda Leite-Ribeiro, Viviane Almeida Sarmento
Journal: F1000Res (2019)
Keywords: dental care, diagnosis, leishmaniasis, mucocutaneous, oral
MeSH terms: Face / pathology, Leishmaniasis, Mucocutaneous / diagnosis, Mouth Diseases / parasitology, Case Reports, Adult, Biopsy, Brazil, Child, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Skin / parasitology, Young Adult

Dentists play a fundamental role in the early diagnosis of oral leishmaniasis. Although these lesions are rare at oral mucosa, this is one of the manifestations sites of the disease This study reports seven clinical cases of orofacial mucocutaneous leishmaniasis. All had leishmaniasis diagnosis confirmed by laboratory tests, with orofacial involvement. Five out of the seven cases were males, and in four cases, patients had associated comorbidities. Late diagnosis was observed, resulting in treatment delay and increased hospitalization stay. One patient had severe psychological consequences due to facial deformity. The lack of differential diagnosis due the great variability of clinical presentation of the lesions and frequent unspecific histopathology represent a challenge for the dentist. In two reported cases, there were unspecific biopsy results. This series of cases highlights the importance of a multidisciplinary approach in the diagnosis and treatment of oral and perioral leishmaniasis. Patients with atypical lesions, originating from or living in endemic regions, should be investigated for leishmaniasis. These procedures could avoid delays in diagnosis and decrease the risk of disease dissemination.