OpenMed/multicare-articles huggingface dataset:
Unusual case of parietal metastasis from papillary thyroid carcinoma: a case report
Authors: Evrard Niyonkuru, Zineb Sami, Fadwa Bouyalik, Samira Benayad, Mohamed El Karroumi, Mehdi Karkouri
Journal: Pan Afr Med J (2022)
Keywords: papillary thyroid carcinoma, case report, metastasis, skin
MeSH terms: Thyroid Neoplasms / diagnosis, Thyroid Neoplasms / surgery, Thyroidectomy, Case Reports, Female, Humans, Lymph Nodes, Middle Aged, Thyroid Cancer, Papillary

Parietal metastasis is a very rare secondary location of papillary thyroid carcinoma. It associated with poor prognosis. We report a case of a 61-year-old woman with parietal metastasis from papillary thyroid carcinoma. The patient presented a parietal nodule on the back. In her past history, she had been diagnosed papillary thyroid carcinoma after total thyroidectomy and also reoperated for local recurrence. The CT scan performed has revealed metastasis to the lungs, bones, lymph nodes and adrenal glands. The parietal nodule was excised and submitted for histopathological examination. The histologic and immunohistochemical findings confirmed the thyroid origin. Although papillary thyroid carcinoma is a relatively indolent tumour, it can exhibit an unusual metastatic behaviour.
Atypical hemolytic uremic syndrome in a patient with HIV treated with eculizumab: A case report
Authors: Danilo E Trujillo González, Dagoberto Duarte Misol, Nicolás Ariza Ordoñez, Fabian Andres Salgado Zamora, Henry A Millan Prada, Eduardo Zuñiga R, Alejandra Molano Triviño
Journal: IDCases (2023)
Keywords: acute kidney injury, atypical hemolytic uremic syndrome, eculizumab, human immunodeficiency virus, plasma therapeutic exchange, thrombotic microangiopathy
MeSH terms: Case Reports

Thrombotic microangiopathy defines a group of pathologies characterized by microvascular dysfunction with the concurrence of microangiopathic hemolytic anemia, thrombocytopenia, and organ damage. It represents the most frequent microvascular manifestation of human immunodeficiency virus (HIV) infection. We report the case of a man in the seventh decade of life with a recent diagnosis of infection by HIV, who develops hemolytic uremic syndrome, requiring continuous renal replacement therapy and plasma replacement therapy, without response, ADAMTS13 with preserved activity, ruling out other etiologies (infectious, metabolic, and genetic) with successful response to eculizumab.
Pericardial Effusion due to Primary Malignant Pericardial Mesothelioma: A Common Finding but an Uncommon Cause
Authors: Valery Istomin, David S Blondheim, Simcha R Meisel, Aaron Frimerman, Moshe Lapidot, Ronit Rachmilevitch
Journal: Case Rep Med (2016)

This case report describes a 37-year-old female who was admitted to our Emergency Department because of shortness of breath. On physical examination, she had dyspnea and tachycardia and blood pressure was 80/50 mmHg with a pulsus paradoxus of 22 mmHg. Neck veins were distended, heart sounds were distant, and dullness was found on both lung bases. Her chest X-ray revealed bilateral pleural effusion and cardiomegaly. On both computed tomography and echocardiography the heart was of normal size and a large pericardial effusion was noted. The echocardiogram showed signs of impending tamponade, so the patient underwent an emergent pericardiocentesis. No infectious etiology was found and she was assumed to have viral pericarditis and was treated accordingly. However, when the pericardial effusion recurred and empirical therapy for tuberculosis failed, a pericardial window was performed. A typical staining pattern for mesothelioma was found on her pericardial biopsy specimen. Since no other mesodermal tissue was affected, a diagnosis of primary malignant pericardial mesothelioma was made. Chemotherapy was not effective and she passed away a year after the diagnosis was made. This case highlights the difficulties in diagnosing this uncommon disease in patients that present with the common finding of pericardial effusion.
Giant superficial angiomyxoma of the male perineum: A case report
Authors: Sheng Yan, Yuhua Zou, Xinzhi Liao, Cunzhi Zhong, Shengyin Liu, Sigen Huang, Junrong Zou, Quanliang Liu
Journal: Front Surg (2023)
Keywords: case report, clinical pathology, perineal tumor, superficial angiomyxoma, surgical removal
MeSH terms: Case Reports

Superficial angiomyxoma (SA) is a rare benign tumor that occurs either in the superficial dermis or subcutaneously. It often occurs in the trunk, neck, or limbs, and grows slowly. The diameter of the tumor is usually less than 5 cm. A giant SA of the perineum in men is very rare. We detailed the diagnosis and treatment of male patients with perineal SA and performed a literature review. We report a case of a 42-year-old male patient. He was admitted to hospital with a perineal mass found more than 1 year previously. A pelvic contrast-enhanced computed tomography scan in our hospital suggests that a round slightly hypointense foci of about 6.0 cm × 8.6 cm × 4.5 cm in size with still clear borders was seen below the penile corpus cavernosum in the perineum. We performed a perineal mass excision under continuous epidural anesthesia. A postoperative pathology report diagnosed perineal SA. There was no recurrence at follow-up for 27 months up to May 2022. Perineal SA is rare and should be combined with patient history and imaging to ensure complete excision of the mass margins. Adherence to long-term postoperative follow-up is the key to curing this case.
Orthodontic Treatment of Ankylosed Maxillary Incisor through Osteogenic Distraction and Simplified Biomechanics
Authors: Daniel Gheur Tocolini, Priscila de Oliveira Silva, Iduilton Grabowski Jr, Julia Carelli, Nathaly Dias Morais, Gisele Maria Correr, Francielle Topolski, Alexandre Moro
Journal: Case Rep Dent (2019)
MeSH terms: Case Reports

Ankylosed teeth may have a significant esthetic and functional impact especially at the anterior segment of the upper arch. Treatment of ankylosed teeth is challenging. The objective of this case report is to describe a clinical case in which an ankylosed tooth was treated with the use of osteogenic distraction associated with simplified orthodontic biomechanics. A 17-year-old female Caucasian patient presented with a Class II malocclusion, severe maxillary dental crowding, moderate mandibular dental crowding, anterior open bite, upper midline deviation to the right, and upper right central incisor in infraocclusion due to ankylosis. Treatment involved the use of the ankylosed tooth as anchorage for the distalization of the right upper segment to correct the Class II malocclusion and to create space prior to surgery. After one week of surgical osteotomy, traction of the tooth and bone segment was initiated with the use of intermaxillary elastics. The ankylosed tooth was moved to the desired position. Bone formation and mucogingival tissue adaptation were observed. Thus, esthetic and functional improvement was achieved. Osteogenic distraction associated with simplified orthodontic biomechanics is an alternative to the treatment of ankylosed teeth which can replace the use of distractor screws, making treatment simpler and more accessible.
Hemophagocytic Lymphohistiocytosis in Pregnancy: A Case Series and Review of the Current Literature
Authors: Jessica Parrott, Alexander Shilling, Heather J Male, Marium Holland, Cecily A Clark-Ganheart
Journal: Case Rep Obstet Gynecol (2019)
MeSH terms: Case Reports

Background:
Hemophagocytic lymphohistiocytosis (HLH) is a rare disease that can be fatal in pregnancy. We report two cases of severe HLH that highlight etoposide use in pregnancy.
Case 1:
28-year-old G2P1 with lupus presented at 18 weeks with acute hypoxic respiratory failure, hepatic dysfunction, leukopenia, thrombocytopenia, and elevated ferritin. Bone marrow biopsy confirmed HLH. Etoposide and corticosteroid treatment was initiated per HLH protocol; however clinical status declined rapidly. Fetal demise occurred at 21 weeks and she subsequently suffered a massive cerebral vascular accident. She was transitioned to comfort measures and the patient deceased.
Case 2:
37-year-old G4P3 presented at 25 weeks with fever, acute liver failure, thrombocytopenia, and elevated ferritin. HLH treatment was initiated, including etoposide, and diagnosis confirmed with liver biopsy. Fetal growth restriction was diagnosed at 27 weeks. Delivery occurred at 37 weeks. The neonate was found to be CMV positive despite negative maternal serology.
Conclusion:
The addition of etoposide to corticosteroid use is a key component in HLH treatment of nonpregnant individuals. While this is usually avoided in pregnancy, the benefit to the mother may outweigh the potential harm to the fetus in severe cases and it should be strongly considered.
Management of Pseudohypoparathyroidism Type 1a during Pregnancy and Labor: A Case Report
Authors: Anju Singh, Neelam Agarwal, Seema Chopra, Pooja Sikka, Vanita Suri, Bhupesh Kumar, Pinaki Dutta
Journal: Case Rep Obstet Gynecol (2012)

Pseudohypoparathyroidism is rare during pregnancy and poses multiple challenges related to its diagnosis and management during pregnancy. We hereby report a case of a young woman who was diagnosed to have type 1a pseudohypoparathyroidism. She was managed by multidisciplinary team and had good maternal and perinatal outcome. Management-related issues are discussed here in detail.
Hypophosphatemic rickets: presenting features of fanconi-bickel syndrome
Authors: Mahua Roy, K Bose, D K Paul, Puja Anand
Journal: Case Rep Pathol (2011)
MeSH terms: Case Reports

Fanconi-Bickel Syndrome (FBS) is a rare variety of glycogen storage disease (GSD). Characterized by massive hepatomegaly due to glycogen accumulation, severe hypophosphatemic rickets, and marked growth retardation due to proximal renal tubular dysfunction. We report a young boy presented as hypophosphatemic rickets with hepatomegaly and subsequently diagnosed as FBS.
Management of severe childhood pneumonia by day care approach in developing countries
Authors: Yasmin Jahan, Sm Atiqur Rahman, Abu Sayeed Chowdhury, Md Moshiur Rahman
Journal: Health Promot Perspect (2018)
Keywords: day care approach, developing countries, severe childhood pneumonia
MeSH terms: Case Reports

Background: Pneumonia is a major cause of child mortality among children under 5 years, worldwide. Pneumonia infection may be caused by bacteria, viruses, or fungi in single or in both lungs. According to recent criteria developed by the World Health Organization(WHO) in September (2013), pneumonia can be classified into severe pneumonia, pneumonia and no pneumonia. Most of the deaths occur from severe pneumonia. Methods: Disease management of severe childhood pneumonia requires early identification,prompt referral and the availability of intensive quality care. Under 5 years old children with severe pneumonia should receive day care, with antibiotic treatment, feeding, and supportive care with similar 24-hour hospital treatment. Results: Considering that difficulties, International Centre for Diarrheal Disease Research,Bangladesh (ICDDR, B) initiated Day Care Approach (DCA) model, as an innovative, safe,effective and less expensive alternative to hospital management of severe childhood pneumonia.A 24 months old girl came to the health care center with severe breathing difficulty, cough,history of fever and head nodding. The management described below was continued daily until there was clinical improvement; no fever, no fast breathing, no lower chest wall in drawing, no danger signs, no rales on auscultation, and no hypoxemia. Conclusion: Considering the WHO case management protocol for severe pneumonia, DCA recommends that diagnosis of severe pneumonia should be based primarily on visible clinical parameters. On that basis, severe childhood pneumonia can be successfully managed at daycare clinics including for children with hypoxemia who is required prolong (4-6 hours) oxygen therapy.
Virus-negative active lymphocytic myocarditis progressing to a fibrotic stage
Authors: Edouard Gerbaud, Anne Vital, Matthew Erickson, Michel Montaudon, Emmanuel Harcaut, Jean Luc Pellegrin, François Laurent, Pierre Coste
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

We report a fairly special case of lymphocytic myocarditis progressing to a fibrotic stage, described using multimodality imaging and confirmed on histopathology. This paper presents an uncommon diagnosis with a probable guarded prognosis.
Synchronous Leydig Cell Tumor and Seminoma in the Ipsilateral Testis
Authors: Ifeyinwa E Obiorah, Alexandra Kyrillos, Metin Ozdemirli
Journal: Case Rep Urol (2018)
MeSH terms: Case Reports

Leydig cell tumor is a rare sex cord tumor that accounts for 1-3% of all testicular neoplasms. Seminomas are more common and occur in 30-40% of testicular tumors. Leydig cell tumors are derived from undifferentiated gonadal mesenchyme and the concurrent development of the tumor and a seminoma which are derived from germinal epithelium in an ipsilateral testis is extremely rare. Here we report a case of ipsilateral Leydig cell tumor and seminoma occurring in a 38-year-old man with a left testicular mass. The key to diagnosis is dependent on histopathology and immunohistochemistry. To our knowledge, this is the first diagnosis of the two disease entities in a unilateral testis using immunohistochemistry. Increased awareness of the entity is important in order to distinguish Leydig cell tumor and seminomas from other malignancies due to difference in therapeutic management.
Case Report: Ketogenic Diet Is Associated With Improvements in Chronic Obstructive Pulmonary Disease
Authors: Nicholas G Norwitz, Russell Winwood, Brianna J Stubbs, Dominic P D'Agostino, Peter J Barnes
Journal: Front Med (Lausanne) (2021)
Keywords: case report, chronic objective pulmonary disease, forced expiratory volume 1, inflammation, ketogenic diet
MeSH terms: Case Reports

Chronic Obstructive Pulmonary Disease (COPD) is a debilitating inflammatory respiratory condition that presents with worsening breathing difficulties and it is assumed to be progressive and incurable. As an inflammatory disease, COPD is associated with recruitment of immune cells to lung tissue and increased levels of pro-inflammatory cytokines, including TNF-α, IL-1β, IL-6, IL-8, and GM-CSF. Low-carbohydrate ketogenic diets have anti-inflammatory properties that could, in theory, improve COPD symptoms and progression. Herein, we report on a 54-year-old patient (C.A.) with COPD who adopted a ketogenic diet (70% calories from fat). Subsequently, C.A. experienced a reduction in inflammatory markers in association with a meaningful improvement in lung function. His inflammatory markers decreased into the normal range and his forced expiratory volume increased by 37.5% relative to its pre-ketogenic diet value. Future research should explore nutritional ketosis and ketogenic diets as possible therapeutic options for individuals with COPD.
Concealment of trauma and occupational accidents among Fukushima nuclear disaster decontamination workers: A case report
Authors: Toyoaki Sawano, Hayato Tanaka, Daiki Watanabe, Akihiko Ozaki, Manabu Tsukada, Yoshitaka Nishikawa, Hiroaki Saito, Yuki Shimada, Tomohiro Morita, Hiromichi Ohira, Masaharu Tsubokura
Journal: J Occup Health (2020)
Keywords: fukushima, decontamination worker, environmental health, nuclear disaster, socioeconomic status, workspace safety
MeSH terms: Accidents, Occupational, Decontamination, Fukushima Nuclear Accident, Hemopneumothorax / therapy, Rib Fractures / therapy, Case Reports, Humans, Japan, Male, Middle Aged, Thoracostomy

Objectives:
Limited information exists concerning occupational risks in decontamination work after the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident. Workers involved tend to be migrant workers, face various health risks, and are usually from a low socioeconomic background and generally have difficulty in finding employment. We report a specific case to illustrate the way these workers tend to get injured during working hours and draw attention to the problems arising.
Case presentation:
A 59-year-old Japanese male decontamination worker was referred to our emergency department after a fall while he was working in an Exclusion Zone surrounding the FDNPP. He was blind in his right eye. He was diagnosed with traumatic multiple rib fractures and a tube thoracostomy was performed. He was discharged from hospital after 7 days. Payment has been changed from "occupational accident," which is required to be reported to the Local Labor Standards Office, to "general medical treatment" which is no obligation.
Conclusion:
Trauma or physical injury of any kind is an occupational hazard for workers, especially those operating in the chaotic and unpredictable environments following any disasters. Companies employing such workers and owners of any facilities or locations in which they may be working are responsible for the safety of their workers. They should provide appropriate training and should comply with all prevailing Employment Laws and follow mandatory safety regulations. If companies and authorities are in breach of any laws, ignore their responsibilities, or jeopardize the health of their workers, they should be held accountable.
Tectonic Keratoplasty to Restore the Bulbar Wall after Block Excision of Benign and Malignant Intraocular Tumors
Authors: Emilio Balestrazzi, Luigi Mosca, Maria Antonietta Blasi, Maria Ilaria Giannico, Angelo Balestrazzi
Journal: J Ophthalmol (2019)

Purpose:
To report the surgical treatment and follow-up of tumors of the anterior uvea and epithelial cysts of the anterior chamber in 4 patients submitted to block excision and tectonic corneal graft between 2008 and 2012.
Methods:
This is a retrospective, nonrandomized case series. Two patients were affected by anterior uveal malignant melanoma, and 2 patients were referred to us for large epithelial iris cysts with anterior chamber angle involvement and partial corneal failure. A simultaneous block removal of the lesion and adjacent iris, cornea (when necessary), ciliary body, and sclera was performed; the resulting defect was covered by a tectonic whole thickness corneal graft. Follow-up ranged from 2 to 7 years (mean time: 5 ± 1.6 MD).
Results:
Local control of malignant melanoma was observed during the follow-up, but cataract surgery was planned in both patients and pars plana vitrectomy for vitreous hemorrhage occurred in one case. No recurrence of cysts was detected. After iris cysts excision, a planned second-time surgery was necessary in one patient: optical penetrating keratoplasty, centered on the visual axis, implantation of one refractive IOL (intraocular lens) in the bag, and one cosmetic IOL in the sulcus, to restore the iris diaphragm.
Conclusions:
Block excision followed by the tectonic corneal graft seems to be the treatment of choice for selected cases of epithelial cysts of the anterior chamber and anterior uvea melanomas with epibulbar extension. Further surgery, as a second step, could be required to improve functional results of this challenging technique.
Extraskeletal osteosarcoma of the thigh: an autopsy case report
Authors: Akihito Nagano, Takatoshi Ohno, Yutaka Nishimoto, Kazunari Yamada, Katsuji Shimizu
Journal: Sarcoma (2009)
MeSH terms: Case Reports

We report a case of extraskeletal osteosarcoma (ESOS) and autopsy findings. A 35-year-old man presented with an ossified tumor in the right thigh and lung metastasis. The lung tumors continued to develop despite multiagent chemotherapy and caused death within 8 months. Autopsy revealed many secondary lesions in the lungs, especially in the left lung. Histopathologically, the primary tumor and one of the secondary tumors showed proliferation of spindle-shaped tumor cells focally forming lace-like osteoid material. Therefore, we made a definite diagnosis of ESOS.
Symptom Locus and Symptom Origin Incongruity in Runner's Dystonia - Case Study of an Elite Female Runner
Authors: Issei Ogasawara, Noriaki Hattori, Gajanan S Revankar, Shoji Konda, Yuki Uno, Tomohito Nakano, Yuta Kajiyama, Hideki Mochizuki, Ken Nakata
Journal: Front Hum Neurosci (2021)
Keywords: electromyography, female athlete, involuntary movement, motion capture system, movement disorder, running, task-specific focal dystonia, yips

Objectives: Runner's dystonia is a task-specific dystonia that occurs in the lower limbs and trunk, with diverse symptomatology. We aimed to identify the origin of a dystonic movement abnormality using combined three-dimensional kinematic analysis and electromyographic (EMG) assessment during treadmill running. Participant: A 20-year-old female runner who complained of right-foot collision with the left-leg during right-leg swing-phase, which mimicked right-ankle focal dystonia. Results: Kinematic and EMG assessment of her running motion was performed, which showed a significant drop of the left pelvis during right-leg stance-phase, and a simultaneous increase of right hip adductor muscle activity. This resulted in a pronounced adduction of the entire right lower limb with respect to the pelvis segment. Trajectories of right foot were seen to encroach upon left-leg area. Discussion: These findings suggested that the symptom of this runner was most likely a form of segmental dystonia originating from an impaired control of hip and pelvis, rather than a distal focal ankle dystonia. Conclusion: We conclude that, for individualized symptom assessment, deconstructing the symptom origin from its secondary compensatory movement is crucial for characterizing dystonia. Kinematic and EMG evaluation will therefore be a prerequisite to distinguish symptom origin from secondary compensatory movement.
Idiopathic tumoral calcinosis in hand: a case report
Authors: Chris Xu, Josephine Alexa Potter, Christopher David Carter, Clayton Miles Cooper Lang
Journal: Eplasty (2014)
Keywords: calciphylaxis, hand, idiopathic, surgery, tumoral calcinosis
MeSH terms: Case Reports

Objective:
Tumoral calcinosis is an uncommon lesion, composed of ectopic calcified tissue, most commonly seen in the large joints of the hips, knees, shoulders, and elbows. The involvement of the hand in a healthy patient is extremely rare, and therefore this condition can cause diagnostic confusion. The purpose of this report is to describe one case of idiopathic tumoral calcinosis that occurred in the left hand of a 35-year-old healthy female patient.
Methods:
The patient presented with 2-day history of acutely swelling and painful left hand middle finger metacarpal phalangeal joint without any precipitants.
Results:
All biochemical, radiological, and histopathological evidence suggested idiopathic tumoral calcinosis of the hand.
Conclusions:
In this case, surgery provided the patient with instant symptomatic relief and full functional recovery of that joint.