OpenMed/multicare-articles huggingface dataset:
Immediate Esthetic Rehabilitation of Periodontally Compromised Anterior Tooth Using Natural Tooth as Pontic
Authors: K Pavan Kumar, Surya Kumari Nujella, S Sujatha Gopal, K Karthik Roy
Journal: Case Rep Dent (2016)

For patients who require removal of anterior teeth and their replacement various treatment modalities are available. With advancement in technology and availability of glass/polyethylene fibres, use of natural tooth as pontic with fibre reinforced composite restorations offers the promising results. The present case report describes management of periodontally compromised mandibular anterior tooth using natural tooth pontic with fibre reinforcement. A 1-year follow-up showed that the bridge was intact with good esthetics and no problem was reported.
Advanced Myoelectric Control for Robotic Hand-Assisted Training: Outcome from a Stroke Patient
Authors: Zhiyuan Lu, Kai-Yu Tong, Henry Shin, Sheng Li, Ping Zhou
Journal: Front Neurol (2017)
Keywords: case report, electromyography, hand exoskeleton, myoelectric pattern recognition, rehabilitation
MeSH terms: Case Reports

A hand exoskeleton driven by myoelectric pattern recognition was designed for stroke rehabilitation. It detects and recognizes the user's motion intent based on electromyography (EMG) signals, and then helps the user to accomplish hand motions in real time. The hand exoskeleton can perform six kinds of motions, including the whole hand closing/opening, tripod pinch/opening, and the "gun" sign/opening. A 52-year-old woman, 8 months after stroke, made 20× 2-h visits over 10 weeks to participate in robot-assisted hand training. Though she was unable to move her fingers on her right hand before the training, EMG activities could be detected on her right forearm. In each visit, she took 4× 10-min robot-assisted training sessions, in which she repeated the aforementioned six motion patterns assisted by our intent-driven hand exoskeleton. After the training, her grip force increased from 1.5 to 2.7 kg, her pinch force increased from 1.5 to 2.5 kg, her score of Box and Block test increased from 3 to 7, her score of Fugl-Meyer (Part C) increased from 0 to 7, and her hand function increased from Stage 1 to Stage 2 in Chedoke-McMaster assessment. The results demonstrate the feasibility of robot-assisted training driven by myoelectric pattern recognition after stroke.
Platelet thromboembolism after lung transplantation
Authors: Carles Bravo, Joaquim Majó, Fernando Ruiz, Laura Muntaner, Víctor Monforte, Joan Solé, José Maestre, Ferran Morell, Antonio Roman
Journal: J Transplant (2009)
MeSH terms: Case Reports

Lung transplant patients have an increased risk of pulmonary embolism which is often associated with hypercoagulability disorders. We present a case of sudden death resulting from pulmonary intravascular platelet thromboembolism following a single-lung transplant.
Self inflicted human teeth bites: a case report
Authors: Satinder Pal Singh, Akashdeep Aggarwal, Sumeet Kaur, Dalbir Singh
Journal: Pan Afr Med J (2014)
Keywords: human bite, fabricated injuries, teeth marks
MeSH terms: Bites, Human / pathology, Self-Injurious Behavior / pathology, Case Reports, Bites, Human / psychology, Deception, Dissent and Disputes, Female, Humans, Middle Aged, Self-Injurious Behavior / psychology, Violence

Human infighting has been a part of our civilization since times immemorial. These incidences may go unnoticed or may attract attention of law enforcing agencies depending upon the severity of the offence. Though weapons are generally employed to inflict injuries, rare cases have been reported in literature where human teeth have been used to serve this purpose. Human bites may be self inflicted or self suffered in connivance with others to level an allegation against an adversary. We are presenting here such a case where such injuries were produced to bring a false charge against a neighbor.
Case Report: Para-infectious cranial nerve palsy after bacterial meningitis
Authors: Giovanni Zanotelli, Lorenzo Bresciani, Mariagiulia Anglani, Alessandro Miscioscia, Francesca Rinaldi, Marco Puthenparampil
Journal: Front Immunol (2022)
Keywords: neisseria meningitidis, bacterial meningitis, facial palsy, parainfectious cranial nerve palsy, parainfectious disease
MeSH terms: Cranial Nerve Diseases / diagnosis, Cranial Nerve Diseases / drug therapy, Cranial Nerve Diseases / etiology, Meningitis, Bacterial / complications, Meningitis, Bacterial / diagnosis, Meningitis, Bacterial / drug therapy, Case Reports, Adult, Anti-Bacterial Agents, Ceftriaxone, Contrast Media, Diplopia, Female, Gadolinium, Humans, Immunoglobulin G, Leukocytosis, Oligoclonal Bands, Paralysis, Prednisolone, Oligoclonal Bands, Ceftriaxone, Gadolinium, Contrast Media, Prednisolone, Immunoglobulin G, Anti-Bacterial Agents

A 27-year-old woman was admitted to our hospital for fever, associated with headache, nausea, and vomiting, and she rapidly developed mild left facial nerve palsy and diplopia. Neurological examination revealed mild meningitis associated with bilateral VI cranial nerve palsy and mild left facial palsy. As central nervous system (CNS) infection was suspected, a diagnostic lumbar puncture was performed, which revealed 1,677 cells/μl, 70% of which were polymorphonuclear leukocytes. Moreover, multiplex PCR immunoassay was positive for Neisseria meningitidis, supporting the diagnosis of bacterial meningitis. Finally, IgG oligoclonal bands (IgGOB) were absent in serum and cerebrospinal fluid (CSF). Therefore, ceftriaxone antibiotic therapy was started, and in the following days, the patient's signs and symptoms improved, with complete remission of diplopia and meningeal signs within a week. On the contrary, left facial nerve palsy progressively worsened into a severe bilateral deficit. A second lumbar puncture was therefore performed: the CSF analysis revealed a remarkable decrease of pleocytosis with a qualitative modification (only lymphocytes), and oligoclonal IgG bands were present. A new brain MRI was performed, showing a bilateral gadolinium enhancement of the intrameatal VII and VIII cranial nerves bilaterally. Due to suspicion of para-infectious etiology, the patient was treated with oral steroid (prednisolone 1 mg/kg/day), with a progressive and complete regression of the symptoms. We suggest that in this case, after a pathogen-driven immunological response (characterized by relevant CSF mixed pleocytosis and no evidence of IgGOB), a para-infectious adaptive immunity-driven reaction (with mild lymphocyte pleocytosis and pattern III IgGOB) against VII and VIII cranial nerves started. Indeed, steroid administration caused a rapid and complete restoration of cranial nerve function.
Seizure following the Use of the COX-2 Inhibitor Etoricoxib
Authors: Valentina Arnao, Marianna Riolo, Brigida Fierro, Paolo Aridon
Journal: Case Rep Neurol Med (2017)
MeSH terms: Case Reports

We describe a case of epileptic seizures occurring after the use of a COX-2 inhibitor. A 61-year-old man was admitted to our department because of a generalized tonic-clonic seizure. EEG showed generalized slowdown of the activity. Neuroimaging and blood samples studies did not evidence alterations, but a careful pharmacological history revealed that the patient had taken the COX-2 inhibitor etoricoxib to treat lumbago few days before the onset of clinical symptoms. No seizures were reported after etoricoxib discontinuation and an EEG resulted to be normal two months after this. Conclusion. Knowing the pharmacological history of a patient is important for understanding the clinical presentation and selecting appropriate treatment. This is, to the best of our knowledge, the first reported case of generalized seizures associated with the use of COX-2 inhibitors.
Germline Compound Heterozygous Variants Identified in the STXBP2 Gene Leading to a Familial Hemophagocytic Lymphohistiocytosis Type 5: A Case Report
Authors: Vera Maria Dantas, Cassandra Teixeira Valle, Roberta Piccin de Oliveira, Mylena Taíse Azevedo L Bezerra, Cleia Teixeira do Amaral, Raissa Anielle S Brandão, Jussara M Cerqueira Maia, Tirzah Braz Petta
Journal: Front Pediatr (2021)
Keywords: stxbp2, familial hemophagocytic lymphohistiocytosis type 5, hepatosplenomegaly, hyperferritinemia, pancytopenia
MeSH terms: Case Reports

Familial hemophagocytic lymphohistiocytosis (FHL) is a rare, potentially fatal autosomal-recessive immunodeficiency, and STXBP2 mutations have been associated with FHL type 5 (FHL-5). Here, we report a case of a 2-year-old boy who presented with recurrent fever, hepatosplenomegaly, pancytopenia, hyperferritinemia, and hypofibrinogenemia since 4 months of age. His genetic analysis revealed a compound heterozygosity of the STXBP2 gene with a described pathogenic mutation, c.1247-1G>C (splicing acceptor site), harbored by his father and a likely pathogenic variant of uncertain significance (VUS), c.704G>A (p.Arg235Gln), harbored by his mother. He was diagnosed as compound heterozygous for FHL-5 and was treated with the HLH-2004 protocol. Since treatment, this patient has been in remission, and he is being evaluated for a hematopoietic stem cell transplantation (HSCT).
Atrio-Ventricular Block by Legionella Disease
Authors: Kyaw Oo, May Thiri Lwin, Jo Porter
Journal: Cureus (2023)
Keywords: atrioventricular conduction block, atypical pneumonia, community-acquired pneumonia (cap), extrapulmonary legionella, legionella infection, legionella pneumonia, mobitz type 2 av block, second-degree heart block
MeSH terms: Case Reports

Although Legionnaires' disease mainly affects the lungs, it can also present with other systemic involvement, including rare cardiac manifestations. Recognised presentations are endocarditis, myocarditis, pericarditis, and pericardial effusion. A 72-year-old British man presented with a six-day history of dry cough and a four-day history of fever during the peak of the COVID-19 pandemic. His electrocardiogram showed Mobitz type II atrio-ventricular block. Although all the cultures were negative, the chest X-ray demonstrated COVID-19 infection-like features. With high clinical suspicions and chest X-ray features, the polymerase chain reaction of the COVID tests was repeated three times and all were negative. He had a positive urinary Legionella antigen, and his bradycardia and heart block improved after treatment with amoxicillin/clavulanic acid, and clarithromycin. As the electrocardiogram showed Mobitz type II, a permanent pacemaker was implanted. The follow-up pacemaker check showed that he still required active pacing.
Sintilimab-Induced Myocarditis Overlapping Myositis in a Patient With Metastatic Thymoma: A Case Report
Authors: Zi-Xuan Yang, Xuan Chen, Si-Qi Tang, Qing Zhang
Journal: Front Cardiovasc Med (2021)
Keywords: immune checkpoint inhibitor, myasthenia gravis, myocarditis, myositis, sintilimab
MeSH terms: Case Reports

Although immune checkpoint inhibitor (ICI)-related myocarditis has been widely discussed, a lot of gaps and challenges in its clinical course and rational intervention remain elusive. We present the case of a 33-year-old man with a history of metastatic thymoma who developed dyspnea and muscle weakness 1 month after the first dose of sintilimab. He was asymptomatic but found to have a mild elevation of troponin-T and a moderate increase of creatine kinase 20 days after the infusion. Although the scheduled second dose was deferred, he developed dyspnea, left bundle branch block, and left ventricular enlargement that is suggestive of Grade 3 ICI-related myocarditis, complicated with myositis/myasthenia gravis 10 days later. Fortunately, his response to intensive immunosuppressive therapy was good.
Tuberculosis of the patella masquerading as prepatellar bursitis
Authors: S MacLean, S Kulkarni
Journal: Ann R Coll Surg Engl (2013)
MeSH terms: Bursitis / diagnosis, Patella, Tuberculosis, Osteoarticular / diagnosis, Case Reports, Adult, Arthralgia / microbiology, Bursitis / microbiology, Diagnosis, Differential, Edema / microbiology, Female, Humans

Tuberculosis of bone is an uncommon entity in the western world. We present a case of tuberculosis of the patella mimicking prepatellar bursitis in an otherwise fit and well woman of Bangladeshi origin. We believe tuberculosis of bone should form a differential diagnosis of the swollen knee in high-risk patients.
Fibroma of Tendon Sheath Presenting Limited Flexion of the Fingers
Authors: Kazuhiro Maeda, Nokitaka Setsu, Yoshiharu Kato, Akira Kawai, Eisuke Kobayashi
Journal: Case Rep Orthop (2017)
MeSH terms: Case Reports

A 35-year-old Japanese man presented with a 1-month history of limited flexion and radiating pain in the left middle and ring fingers. A physical examination revealed a hard nodular mass in his left palm. Magnetic resonance imaging showed a 2 × 1.5 × 1 cm mass of low intensity on T1-weighted images and high intensity on T2-weighted images and gadolinium enhancement. The tumor was marginally resected, adhering to the flexor digitorum profundus of both the third and fourth fingers. The histological diagnosis was fibroma of tendon sheath. After the surgery, the range of motion and hand function were improved. No recurrence has been observed. Fibroma of tendon sheath usually arises on the fingers and hands with strong attachment to the tendon or tendon sheath. The tumor in the present case probably limited the range of flexion of the fingers by obstruction of the transverse carpal ligament.
Long-term survival with anlotinib as a front-line treatment in an elderly NSCLC patient: A case report
Authors: Jingyi Wang, Xiaoqing Li, Juan Zhou, Dan Qiu, Mengyao Zhang, Lan Sun, Shengwen Calvin Li
Journal: Front Oncol (2023)
Keywords: anlotinib hydrochloride, anti-angiogenesis therapy, case report, chemotherapy, elderly patients, front-line treatment, non-small cell lung cancer, tegafur-uracil
MeSH terms: Case Reports

Background:
Half of the population of non-small cell lung cancer (NSCLC) patients are older than 70 years and have limited therapeutic options due to poor tolerance and being excluded in most clinical trials. Anlotinib hydrochloride, a novel oral multi-target tyrosine kinase inhibitor, has been approved for the standard third-line treatment for NSCLC in China. Herein we report an elderly NSCLC patient without any driver gene mutations who was undergoing anlotinib as a front-line treatment and who achieved long-term survival.
Case summary:
The 77-year-old male patient was admitted to the hospital for chest tightness after engaging in physical activity for a week. The patient has been diagnosed with stage IIIB driver gene-negative squamous cell lung carcinoma. After that, he was treated with anlotinib for 2 years and 10 months from the first diagnosis until the last disease progression. Briefly, anlotinib combined with platinum-based chemotherapy was performed as the first-line therapy over six cycles. After 6 more cycles of anlotinib monotherapy maintenance, disease progression occurred. Then, anlotinib combined with tegafur was administered as a salvage treatment, and the disease was controlled again. After 29 cycles of anlotinib combined with tegafur regimens, the disease progressed finally. The patient achieved a total of 34 months of progression-free survival after anlotinib was used as the front-line treatment. He is still alive with a good performance status now (performance status score: 1).
Conclusion:
This patient achieved long-term survival using anlotinib as a front-line regimen combined with chemotherapy.
Case report: Castleman's disease involving the renal sinus resembling renal cell carcinoma
Authors: Enlong Zhang, Yuan Li, Ning Lang
Journal: Front Surg (2022)
Keywords: castleman disease, case report, computed tomography urography, hyaline vascular type, renal sinus
MeSH terms: Case Reports

Introduction:
Castleman's disease (CD) is a rare benign lymphoproliferative disease that frequently involves the mediastinal thorax and the neck lymph nodes. It rarely affects extrathoracic presentations, with even fewer presentations in the renal sinus.
Patient concerns:
In this report, we present a case of a 40-year-old woman with no significant past medical history who presented Castleman's disease arising in the renal sinus.
Diagnosis and interventions:
The patient visited our hospital with the chief complaint of left renal sinus lesion after renal ultrasonography by regular physical examination. Subsequent abdominal computed tomography urography revealed a soft tissue mass with heterogeneous obvious enhancement in the sinus of the left kidney, which was suspected to be a renal malignant tumor. Hence, the patient underwent a left radical nephrectomy. Histological examination revealed hyperplastic lymphoid follicles in the renal sinus and was finally diagnosed as Castleman's disease of the hyaline vascular type.
Outcomes:
Five days after the surgery procedure, the patient was discharged.
Conclusion:
Due to the low incidence of Castleman's disease in renal sinus, there is a strong likelihood of missed diagnosis or misdiagnosis, and it is, therefore, important to be aware of the risk. Heightened awareness of this disease and its radiographic manifestations may prompt consideration of this diagnosis. Therefore, we explored the radiologic findings to find out some radiologic features suggesting this condition to help clinicians to schedule nephron-sparing surgery in the future.
Solitary Fibrous Tumor of the Umbilical Region in a Pediatric Patient
Authors: Shruti Vaswani, Sudeep Khera, Arvind Sinha
Journal: Ochsner J (2022)
Keywords: molecular diagnostic techniques, solitary fibrous tumors, umbilicus
MeSH terms: Case Reports

Background: Fibrous tumors are rare tumors of mesenchymal origin arising in the serosal surfaces within the body. Although commonly seen in adults, solitary fibrous tumors rarely occur in children. Histopathology and immunohistochemistry are the methods of choice for diagnosing solitary fibrous tumors. Case Report: A 2-year-old male presented with a swelling over the umbilicus for the prior 8 months. The umbilical mass was excised and sent for histopathologic examination. The skin-covered greyish soft tissue mass measured 6 × 5.5 × 4.5 cm, and the cut surface showed a homogenous greyish growth. On microscopic examination, a predominantly well-circumscribed encapsulated tumor was noted, with spindle shaped cells arranged in a haphazard manner and ectatic vascular channels. The cells were immunoreactive for CD34 and signal transducer and activator of transcription 6 (STAT6) and negative for smooth muscle actin, desmin, myogenin, MyoD1, CD99, epithelial membrane antigen, and beta-catenin. Conclusion: The aim of this case is to make clinicians aware of the umbilicus as a rare site of solitary fibrous tumor in children and the diagnostic importance of STAT6.
Case report: Severe hepatic fibrosis induced by chronic cholestasis of congenital biliary dilation treated by laparoscopic surgery after immunonutrition support- An infantile case
Authors: Koshiro Sugita, Shun Onishi, Mitsuru Muto, Nanako Nishida, Ayaka Nagano, Masakazu Murakami, Toshio Harumatsu, Koji Yamada, Waka Yamada, Takafumi Kawano, Satoshi Ieiri
Journal: Front Pediatr (2023)
Keywords: chronic hepatitis, compensated liver cirrhosis, congenital biliary dilation, infant, laparoscopic hepaticojejunostomy
MeSH terms: Case Reports

Introduction:
In some patients with congenital biliary dilation (CBD), biliary cirrhosis has been reported to rapidly progress from the neonatal period to the infantile period. We herein report an infantile case of CBD that showed severe biliary cirrhosis at the diagnosis, which was treated by laparoscopic surgery.
Case presentation:
A 16-month-old girl underwent conservative therapy for liver dysfunction and cholangitis on a remote island of our prefecture. She was transferred to our hospital after the detection of a huge dilated common bile duct on imaging at the previous hospital. Contrast-enhanced computed tomography showed a dilated common bile duct (maximum diameter: 5 cm), thus suggesting CBD. However, her laboratory data on admission showed a poor nutritional status and severe liver dysfunction (Alb, 2.5 mg/dl; AST, 79 IU/L; ALT, 43 IU/L; γ-GTP, 491 mg/dl; D-bil, 0.3 mg/dl; CHE, 90 IU/L; NH3, 123 μg/dl). We initially performed laparoscopic exploration and bile drainage via the gallbladder, noting severe hepatic fibrosis resembling end-stage liver cirrhosis. After placing a drainage tube in the gallbladder, cholangiography was performed. Cholangiography showed Todani type IVa CBD with pancreaticobiliary maljunction. Contrast agent flowing into the duodenum could not be confirmed. The patient received liver-supporting therapy and nutritional support for 7 weeks before definitive surgery. Following the improvement of the hepatic synthetic capacity (Alb, 4.0 mg/dl; AST, 82 IU/L; ALT, 78 IU/L; γ-GTP, 157 mg/dl; D-bil, 0.2 mg/dl; CHE, 232 IU/L; NH3, 75 μg/dl), we performed extrahepatic bile duct excision and hepaticojejunostomy laparoscopically. Laparoscopic surgery was successfully performed along with liver biopsy. Histopathologically, the liver specimen showed chronic hepatitis and fibrosis (F3A2). Biliary scintigraphy showed good bile excretion at postoperative day 15. The postoperative course uneventful, and the patient was discharged on the 23rd day after surgery. A needle liver biopsy six months later showed mild improvement of chronic hepatitis and fibrosis (F2-3A1). The patient was regularly followed at the outpatient clinic.
Conclusions:
Severe liver fibrosis was suspected to be continuous cholestasis of CBD after birth. CBD with severe liver fibrosis may avoid liver transplantation by two-stage surgery with hepatoprotection therapy and immunonutritional support.
Ocular MPox: A report of two cases
Authors: Devina Bhamray-Sanchez, Shyamala Subramanian, Lisa L Dever, Debra Chew
Journal: IDCases (2023)
Keywords: human monkeypox, monkeypox, mpox, ocular mpox, viral infections with ophthalmic manifestations
MeSH terms: Case Reports

We report two cases of ocular MPox in men living with HIV, and review the clinical manifestations, diagnosis, and treatment of this rare syndrome. Our cases highlight the need for early recognition and prompt treatment for this potentially sight threatening infection.
Primary urachal leiomyosarcoma: a case report and literature review of clinical, pathological, and medical imaging features
Authors: Jing Yan, Hongwei Li, Gaowu Yan, Qing Duan, Chunyan Tang, Morgan A McClure, Anup Bhetuwal, Yong Li, Ling Yang, Ruyi Li, Gangcheng Tan, Bo Feng
Journal: Front Oncol (2023)
Keywords: case report, computed tomography, leiomyosarcoma, urachal tumor, urachus
MeSH terms: Case Reports

Background:
Urachal tumors are exceedingly rare, and adenocarcinoma is the most common malignant urachal neoplasm. Here, an especially rare patient of primary urachal leiomyosarcoma from our hospital was reported, and only five patients have been reported thus far since 1981.
Case description:
A 24-year-old man was admitted due to urinary tract symptoms. Both urogenital ultrasonography and contrast-enhanced computed tomography showed a mass at the dome of the urinary bladder. Laparoscopic surgical resection was performed, and histopathologic examination of the mass confirmed the diagnosis of urachal leiomyosarcoma. No recurrence was noted after one and a half years.
Conclusions:
Because the leiomyosarcoma located in the extraperitoneal space of Retzius and may manifest with nonspecific abdominal or urinary symptoms, early and definitive preoperative diagnosis is challenging. Partial cystectomy with complete excision of the urachus is recommended. Because only a few patients have been recorded, clinical outcomes and recurrence risks are difficult to assess.