OpenMed/multicare-articles huggingface dataset:
Bilateral burkitt lymphoma of the ovaries: a report of a case in a child with williams syndrome
Authors: Grace Ifeyinwa Onimoe, Samir Kahwash, Amanda Termuhlen, Thomas G Gross, Elizabeth Varga, Melissa J Rose
Journal: Case Rep Med (2011)
MeSH terms: Case Reports

A 10-year-old female with Williams Syndrome (WS) presented with a two-month history of fatigue, weight loss, and bilateral ovarian masses. Histologic, immunophenotypic, and cytogenetic studies confirmed the diagnosis of Burkitt lymphoma (BL). While there is no established association between the two disorders, this is the third case in the literature of Burkitt lymphoma in a patient with Williams Syndrome.
Glomangiomyoma of the neck in a child in Nepal: a rare case report and literature review
Authors: Bishow Tulachan, Buddha Nath Borgohain
Journal: BMC Ear Nose Throat Disord (2017)
Keywords: angiography, glomangiomyoma, glomus tumour, postoperative
MeSH terms: Case Reports

Background:
Glomangiomyoma is a rare histological variant of glomus tumour. Clinically, it mimicks as a haemangioma and is challenging to diagnose. Its occurrence in the neck of a child has not been previously described.
Case presentation:
A 3 year old girl presented with the complaints of painless progressive neck swelling in the right side for one and half year. Sonography, computed tomography (CT), magnetic resonance imaging (MRI), CT neck angiography and fine needle aspiration cytology (FNAC) were suggestive of vacular malformation i.e. giant haemangioma or arteriovenous malformation. The mass was removed in toto under general anaesthesia without postoperative complications. The histopathology confirmed it to be glomangiomyoma with haemangiopericytoma like features.
Conclusion:
It's an extremely rare variant of glomus tumour and may be the first report of a glomangiomyoma in the neck of a child. Despite a rare entity, it should be borne in mind during differential diagnosis.
Case Report: A Rare Case of a Combination of Omphalocele With Umbilical Teratoma
Authors: Ruslan Bilal, Dastan Rustemov, Zhenis Sakuov, Bahytkaly Ibraimov, Arman Kozhakhmetov
Journal: Front Pediatr (2021)
Keywords: congenital, malformation, newborns, omphalocele, teratoma
MeSH terms: Case Reports

Omphalocele is a congenital malformation of the abdominal wall, which occurs with a frequency of 1-5,000 newborns. The prognosis of treatment often depends on the presence of concomitant malformations. The most common contents of the hernia with omphalocele are the intestinal loops, liver, spleen. However, all organs of the abdominal cavity can be part of the hernial sac with large sizes of omphalocele. Teratoma is a germ cell tumor made up of several different types of tissue, such as hair, muscle, teeth, or bone. They are a type of germ cell tumor and divided into two types: mature and immature. In this article, we describe a rare case of a combination of an omphalocele with a mature teratoma and report the successful single step surgical treatment. On the first day after birth, a simultaneous operation-Removal of teratoma with abdominoplasty was performed. The postoperative period was uneventful, and the child was discharged for recovery.
Insight into Natural History of Congenital Vitiligo: A Case Report of a 23-Year-Old with Stable Congenital Vitiligo
Authors: Chelsea Casey, Stephen E Weis
Journal: Case Rep Dermatol Med (2017)
MeSH terms: Case Reports

Vitiligo is a disorder of skin pigmentation. It affects approximately 1% of the world's population. Vitiligo occurs equally between the sexes with no racial predilections. The majority of cases are acquired and arise between the second and third decades of life. Acquired vitiligo has an unpredictable clinical course. Congenital vitiligo is rare with few reported cases. Due to the rarity of congenital vitiligo, little is known about the clinical course. For patients with acquired or congenital vitiligo, the psychosocial burden can have a profound impact on quality of life. The unknown course of congenital vitiligo can exacerbate the feelings of distress and embarrassment. We report of a case of congenital vitiligo that has been stable for 23 years. The patient had no associated autoimmune disease. The pathogenesis of congenital vitiligo is unknown. This case may be useful to assist clinicians caring for newborns with congenital vitiligo in reassuring parents.
Intracavitary hydatid cyst of the left ventricle in child: an emergency surgery case report
Authors: Hicham El Malki, Abdelkhalek Chetoui, Hicham Fenane, Hicham Benyoussef, Jaafar Rhissassi, Rochde Sayah, Mohamed Laaroussi
Journal: Pan Afr Med J (2014)
Keywords: hydatid cyst, cystectomy, left ventricle
MeSH terms: Cardiac Surgical Procedures, Echinococcosis / surgery, Emergencies, Heart Ventricles / surgery, Case Reports, Child, Echinococcosis / complications, Echinococcosis / diagnosis, Echocardiography, Heart Arrest / parasitology, Heart Arrest / surgery, Heart Ventricles / diagnostic imaging, Heart Ventricles / parasitology, Humans, Magnetic Resonance Imaging, Male, Tomography, X-Ray Computed

Hydatid cysts of the heart are very rare in child. In this report we describe an interesting and unique case of an 8-year-old boy with a large cardiac intracavitary hydatid cyst filling the left ventricle. Echocardiography, computerized tomography, magnetic resonance imaging and serologic test were necessary for the diagnosis. Once assessing the diagnosis, an emergency open heart surgery was necessary to prevent the complications. Surgery associated to medical treatment provides good results as demonstrated in this case report.
Case Report: Ciclosporin A for Refractory Multisystem Inflammatory Syndrome in Children
Authors: Takayuki Suzuki, Tomohiro Suenaga, Aiko Sakai, Masaya Sugiyama, Masashi Mizokami, Ayumi Mizukami, Satoshi Takasago, Hiromichi Hamada, Nobuyuki Kakimoto, Takashi Takeuchi, Mina Ueda, Yuki Komori, Daisuke Tokuhara, Hiroyuki Suzuki
Journal: Front Pediatr (2022)
Keywords: kawasaki disease, mis-c, ciclosporin a, cytokine, phlebitis, treatment option
MeSH terms: Case Reports

Multisystem inflammatory syndrome in children (MIS-C) is a new syndrome involving the development of severe dysfunction in multiple organs after severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. Because the pathophysiology of MIS-C remains unclear, a treatment strategy has not yet been established. We experienced a 12-year-old boy who developed MIS-C at 56 days after SARS-CoV-2 infection and for whom ciclosporin A (CsA) was effective as a third-line treatment. He had a high fever on day 1, and developed a rash on the trunk, swelling in the cervical region, and palmar erythema on day 2. On days 3, he developed conjunctivitis and lip redness, and fulfilled the criteria for classical Kawasaki disease (KD). Although intravenous immunoglobulin infusion (IVIG) was started on day 4, fever persisted and respiratory distress and severe abdominal pain developed. On day 5, because he fulfilled the criteria for MIS-C, methylprednisolone pulse was started for 3 days as a second-line treatment. However, he did not exhibit defervescence and the symptoms continued. Therefore, we selected CsA as a third-line treatment. CsA was so effective that he became defervescent and his symptoms disappeared. In order to clarify the relationship with treatment and the change of clinical conditions, we examined the kinetics of 71 serum cytokines to determine their relationships with his clinical course during the three successive treatments. We found that CsA suppressed macrophage-activating cytokines such as, IL-12(p40), and IL-18 with improvement of his clinical symptoms. CsA may be a useful option for additional treatment of patients with MIS-C refractory to IVIG + methylprednisolone pulse.
Delayed Infection of Occipitocervical Fixation in a Patient with Achondroplasia: A Case Report and Review of Literature
Authors: Milad Shafizadeh, Ehsan Fattahi, Sabra Rostamkhani, Mohsen Rostami, Alireza Khoshnevisan
Journal: Galen Med J (2020)
Keywords: achondroplasia, craniocervical, surgical infection
MeSH terms: Case Reports

Background:
Infections are a major concern in fixation surgeries. Most of the infections could occur in the first three months after the operation.
Case report:
We present a 45-year-old man who known case of achondroplasia who underwent craniospinal fixation and was presented to our clinic with surgical site infection after six years. His instruments were removed, and a halo vest was fixed for the patients. Accordingly, he received intravenous antibiotics, and during nine months' follow-up, no any significant problems were found.
Conclusion:
Infection of instruments in spinal surgeries might be presented years after the surgery. Hence, it needs to be considered by surgeons in patients' follow-ups.
A Case of Capillary Leak Syndrome and Intestinal Ischemia Caused by Rheumatoid Vasculitis
Authors: Atsuki Katsube, Junya Ohara, Yuta Horinishi, Chiaki Sano, Ryuichi Ohta
Journal: Cureus (2023)
Keywords: capillary leak syndrome, general medicine, intestinal perforation, rheumatoid vasculitis, rural hospital
MeSH terms: Case Reports

Rheumatoid vasculitis (RV) is a rare disease associated with rheumatoid arthritis (RA). The incidence of RV has decreased with the development of treatment for RA. However, some patients still develop RV in rural areas, where medical care for autoimmune diseases is inadequate. In this report, we describe a case of RV complicated by an acute exacerbation of generalized ulcerative lesions and capillary leak syndrome in an 86-year-old woman with a severe joint deformity due to RA. RV is a systemic vasculitis characterized by various symptoms. When a patient with RA is diagnosed with poorly controlled joint deformities, general physicians should consider the possibility of RV. Urgent investigation and intensive treatment should be initiated for vasculitis to support the lives of older patients with advanced RA.
A spontaneous mesenteric hematoma with a fistula between the transverse colon resected by laparoscopic surgery: A case report
Authors: Tomoaki Bekki, Takuya Yano, Hiroshi Okuda, Hiroyuki Egi, Shuji Yonehara, Hironobu Amano, Toshio Noriyuki, Masahiro Nakahara
Journal: Int J Surg Case Rep (2019)
Keywords: fistula, hand-assisted laparoscopic surgery (hals), spontaneous mesenteric hematoma

Introduction:
A spontaneous mesenteric hematoma is rare, and its etiology is unclear. We present a very rare case of spontaneous mesenteric hematoma with a fistula to the transverse colon.
Presentation of case:
A 90-year-old male visited our hospital because of lower abdominal pain. The physical examination revealed tenderness in the lower abdomen. The laboratory data revealed anemia and low estimated glomerular filtration rate (eGFR). The abdominal contrast-enhanced computerized tomography (CT) indicated a mass with coexisting low- and high-density areas adjacent to the transverse colon. The mass was diagnosed as a mesenteric hematoma. We selected conservative therapy, because the patient's condition was stable. After 15 days from discharge, he was admitted to the hospital again for the complaint of bloody stool. A fistula with blood flowing out at the splenic flexure was reported on colonoscopy. In the laparoscopic operative findings, the hematoma adhered to the stomach, pancreas and omentum. A hand-assisted laparoscopic transverse colectomy including hematoma in the mesentery was successful. The pathological reports revealed that a spontaneous mesenteric hematoma formed the fistula to the colon. The patient was discharged without any postoperative complication on day 10.
Discussion:
Generally, laparotomy is often chosen for the treatment of mesenteric hematoma. The laparoscopic approach for mesenteric hematoma is useful under the specific condition that the preoperative patient's condition is stable.
Conclusions:
This is the first case of a spontaneous mesenteric hematoma with a fistula to the colon resected safely by laparoscopic surgery.
Bilateral Ptosis as the First Presentation of Guillain-Barre Syndrome
Authors: Ahmad Talebian, Babak Soltani, Motahhareh Talebian
Journal: Iran J Child Neurol (2016)
Keywords: children, guillain-barre syndrome, ptosis, weakness
MeSH terms: Case Reports

Objective Guillain-Barre syndrome (GBS) is the most common cause of acute weakness in children. It has multiple variant forms with different presentations. A rare initial sign is ptosis. In this study, we present a 10-year-old girl with bilateral ptosis without opthalmoplegia followed by a weakness in extremities with a favourable response to intravenous immunoglobulin. Due to the patient's initial eyelid levators, myasthenia gravis was ruled out by a Tensilon test and electrophysiological studies. Our report highlights the possibility of GBS as a cause of isolated ptosis, especially in cases without ophthalmoplegia.
Case report: Thymoid differentiated carcinoma of thyroid: Two cases
Authors: Yanjie Zhao, Jiafeng Liu
Journal: Front Surg (2023)
Keywords: case report, distinguish, misdiagnose, thymoid-differentiated carcinoma of thyroid, tracheotomy
MeSH terms: Case Reports

Objective:
Thymoid carcinoma of the thyroid gland is a rare thyroid tumor, which is often presented in case reports.
Methods:
The clinical data of two patients with thymic carcinoma of the thyroid gland were retrospectively reviewed.
Results:
Case 1: a middle-aged woman who was admitted to the hospital because of "progressive enlargement of the anterior cervical mass for 8 months." Color Doppler ultrasound and CT showed malignant tumor with high possibility of bilateral cervical lymph node metastasis. Total thyroidectomy and bilateral central cervical lymph node dissection were performed. Lymph node biopsy showed the metastasis of small cell undifferentiated thyroid carcinoma. Because the biopsy pathological result was not consistent with the pathology of the primary lesion, immunohistochemistry was performed again, and the final diagnosis was thymic carcinoma in the thyroid gland. Case 2: the patient was an elderly man who was admitted to the hospital due to hoarseness for half a month. During the operation, the tumor invaded the trachea, esophagus, internal jugular vein, common carotid artery, and surrounding tissues. Palliative resection of the tumor was performed. The tumor postoperative pathology suggested thymoid carcinoma of the thyroid gland. It recurred and compressed the trachea 4 months after the operation, resulting in dyspnea of the patient, and finally tracheotomy was performed to alleviate the symptoms.
Conclusion:
Case 1 showed multiple differences in pathological diagnosis, suggesting that the lack of specific imaging and clinical manifestations of thymoid-differentiated thyroid carcinoma made the diagnosis so difficult. Case 2 progressed rapidly, suggesting that thymoid-differentiated thyroid carcinoma was not always inert, and the treatment and follow-up should follow the principle of individualization.
Primary hyperparathyroidism masquerading as rickets: diagnostic challenge and treatment outcomes
Authors: Deep Dutta, Manoj Kumar, Ram Narayan Das, Saumik Datta, Dibakar Biswas, Sujoy Ghosh, Satinath Mukhopadhyay, Subhankar Chowdhury
Journal: J Clin Res Pediatr Endocrinol (2013)
MeSH terms: Hyperparathyroidism, Primary / diagnosis, Rickets / diagnosis, Case Reports, Child, Diagnosis, Differential, Female, Humans, Hyperparathyroidism, Primary / therapy, Parathyroidectomy, Quality of Life, Rickets / therapy, Treatment Outcome

Primary hyperparathyroidism (PHPT) is extremely uncommon among children and is more likely to be associated with genetic syndromes, multiglandular involvement, and more severe symptoms. Rickets can very rarely be the presenting feature of PHPT in children. Rickets was diagnosed in a 12-year-old girl presenting with short stature, genu valgum, eversion deformity at the ankle joints, and flat feet. Radiograms showed generalized osteopenia, widening of the distal ends of the long bones along with splaying, cupping and fraying. Biochemical evaluation revealed low serum calcium (7.8 mg/dL), low phosphorus (1.4 mg/dL), vitamin-D deficiency [25-hydroxy-vitamin-D (25(OH)D): 8.7 ng/mL], and elevated intact parathyroid hormone (PTH, 811 pg/mL). Re-evaluation due to lack of clinical improvement following vitamin-D and calcium supplementation revealed hypercalcemia 11.9 mg/dL, normal 25(OH)D 41 ng/mL, persistence of elevated PTH 632 pg/mL. A 99mTc-sestamibi scan showed increased uptake at the lower pole of the right lobe of the thyroid. A right inferior parathyroidectomy was performed. Histopathology revealed chief cell type parathyroid adenoma. Last evaluated 4 months after surgery, the bone pains and proximal weakness had resolved, with significant improvement in the patient's quality of life. Rickets in the setting of PHPT often masks the classical phenotype of PHPT. In a child with rickets, lack of improvement following vitamin-D supplementation, hypercalcemia at presentation or following vitamin-D supplementation are warning signs which necessitate further evaluation to rule out PHPT.
Diabetic Myonecrosis: A Diagnostic and Treatment Challenge in Longstanding Diabetes
Authors: Lima Lawrence, Oscar Tovar-Camargo, M Cecilia Lansang, Vinni Makin
Journal: Case Rep Endocrinol (2018)
MeSH terms: Case Reports

Objective:
Diabetes mellitus is associated with microvascular and macrovascular complications; the most commonly recognized ones include diabetic nephropathy, retinopathy, and neuropathy. Less well-known complications are equally important, as timely recognition and treatment are essential to decrease short- and long-term morbidity.
Methods:
Herein, we describe a case of a 41-year-old female with longstanding, uncontrolled type 2 diabetes, who presented with classical findings of diabetic myonecrosis.
Results:
Our patient underwent extensive laboratory and imaging studies prior to diagnosis due to its rarity and similarity in presentation with other commonly noted musculoskeletal conditions. We emphasize the clinical presentation, laboratory and imaging findings, treatment regimen, and prognosis associated with diabetic myonecrosis.
Conclusion:
Diabetic myonecrosis is a rare complication of longstanding, poorly controlled diabetes mellitus. The diagnosis requires a high index of suspicion in the right clinical setting: acute onset nontraumatic muscular pain with associated findings on clinical exam, laboratory studies, and imaging. While the short-term prognosis is good, the recurrence rate remains high and long-term prognosis is poor given underlying uncontrolled diabetes and associated sequelae.
Bowel perforation during enema examination through a colostomy without leakage of contrast agent: A case report
Authors: Kaoru Katano, Yuichiro Furutani, Chikashi Hiranuma, Masakazu Hattori, Kenji Doden, Yasuo Hashidume
Journal: Int J Surg Case Rep (2020)
Keywords: bowel enema, case report, colostomy, perforation
MeSH terms: Case Reports

Introduction:
Enema examination is considered safe, but in rare cases, complications may result. Here, we report a rare case of iatrogenic bowel perforation during enema examination through a colostomy without leakage of contrast agent.
Presentation of case:
A 36-year-old man who had undergone a sigmoid loop colostomy was diagnosed with ulcerative colitis. A bowel enema through a colostomy was performed by nurses and radiological technologists. During the procedure, a balloon catheter was inserted into the proximal lumen of the colostomy, and the balloon was inflated. The patient developed severe abdominal pain a few minutes following withdrawal of the catheter. Computed tomography showed intraperitoneal free air, although contrast agent leakage into the intraperitoneal cavity was not observed. The patient underwent emergency laparotomy. Intraoperatively, there was a 3-cm bowel perforation just inside the colostomy where the inflated balloon was pressing.
Discussion:
The perforation site may have been sealed by the inflated balloon during the enema examination. In addition, the patient maintained a supine position during and after the examination. This led to contrast agent accumulating on the dorsal side and not leaking out from the perforation site after the balloon was deflated.
Conclusion:
Iatrogenic bowel perforation can occur without leakage of contrast agent during enema examination through a colostomy, and the examination should be performed under the supervision of an attending doctor. In the case of an enema examination through a colostomy, clinicians must be aware of the possibility of bowel perforation even if leakage of contrast agent is not observed.
Suspect Guillain-Barré syndrome in a male rhesus macaque ( Macaca mulatta)
Authors: Tamara Becker, Florian Pieper, David Liebetanz, Martina Bleyer, Annette Schrod, Kerstin Maetz-Rensing, Stefan Treue
Journal: Primate Biol (2017)

Guillain-Barré syndrome (GBS) is a rare, mainly acute inflammatory polyneuropathy in humans. It is frequently post-infectious with auto antibodies being formed against myelin sheaths, resulting in a progressive and more-or-less severe paralysis of the motor neuron and cranial nerves. Mortality is low and 60 % of the patients recover completely from the disease after intensive treatment. In animals, there are a few diseases that closely resemble GBS, but cases of GBS in monkeys seem to be scarce. In this case report, the clinical course of a progressive tetraplegia in a male rhesus macaque is described. Clinical, cerebrospinal fluid (CSF), electroneurography (ENG) and electromyography (EMG), and pathological findings revealed symptoms very similar to human GBS.
Silicone-Induced Foreign Body Reaction: An Unusual Differential Diagnosis of Posterolateral Hip Pain
Authors: Karishma Ramsubeik, Omar Tolaymat, Gurjit Kaeley
Journal: Case Rep Med (2018)
MeSH terms: Case Reports

Background:
Silicone injection is commonly used for soft tissue augmentation for esthetic purposes. It is not without complications.
Case presentation:
We present a case of a 31-year-old woman presenting with refractory left lateral hip pain. Magnetic resonance imaging of the patient's pelvis revealed innumerable small low signal foci throughout the gluteus maximus and overlying subcutaneous fat bilaterally consistent with injectable material, possibly silicone.
Conclusions:
This case report emphasizes that silicone-induced granulomatosis must be considered in the differential diagnosis of hip pain when evaluating a patient who has had access to plastic surgery or clandestine operators.