OpenMed/multicare-articles huggingface dataset:
A case of postoperative spontaneous intussusception after laparoscopic low anterior resection for rectal cancer
Authors: Young Wan Kim
Journal: Mil Med Res (2016)
Keywords: intussusception, postoperative complications, rectal neoplasms

Background:
Intussusception refers to a condition in which a segment of the intestine invaginates into the lumen of an adjacent segment of the intestine. Postoperative intussusception after gastrointestinal surgery is an uncommon clinical condition, and there is only one case report of small bowel intussusception after rectal cancer surgery. Here, we report a case of spontaneous small bowel intussusception following laparoscopic total mesorectal excision for rectal cancer.
Case presentation:
A 56-year-old female military officer was referred to the Colorectal Surgical Department for mid-rectal cancer, 8 cm from the anal verge. The patient underwent laparoscopic low anterior resection and diverting loop ileostomy. On postoperative day 3, the patient complained of vomiting and abdominal pain, and a follow-up abdomino-pelvic computed tomography scan showed an ileo-ileal type intussusception. After two days of surgical observation, her clinical symptoms were not resolved. The patient underwent exploratory laparotomy. On exploration, intussusception was found 40 cm proximal to the loop ileostomy site. Segmental resection of the ileum was carried out, and there was no pathological leading point on the resected ileum. The patient was discharged on postoperative day 14 after the second operation and has remained in good health for two years.
Conclusion:
We present a case of spontaneous small bowel intussusception after laparoscopic total mesorectal excision for rectal cancer that was treated by surgical resection 5 days after the index surgery.
Cheilitis granulomatosa associated with Melkersson-Rosenthal syndrome
Authors: Denise Utsch Gonçalves, Mariana Moreira de Castro, Cláudia Pena Galvão, Alexandre Zoni Rodrigues Brandão, Míriam Cabral Moreira de Castro, José Roberto Lambertucci
Journal: Braz J Otorhinolaryngol (2007)
MeSH terms: Cheilitis / complications, Melkersson-Rosenthal Syndrome / complications, Case Reports, Adolescent, Female, Glucocorticoids / administration & dosage, Humans, Injections, Intralesional, Melkersson-Rosenthal Syndrome / drug therapy, Treatment Outcome, Triamcinolone / administration & dosage, Glucocorticoids, Triamcinolone

Melkersson-Rosenthal syndrome (MRS) consists of persistent or recurrent orofacial edema, relapsing facial palsy and fissured tongue. The complete triad of symptoms is uncommon, varying from 8 to 25%. The presentation of only one symptom is more common. The most frequent complaint is facial edema and enlargement of the lips. We describe a case of a 17-year-old Brazilian girl with limited edema of the lower lip and fissured tongue due to MRS. Her complaints had started two years before. She referred previous clinical treatments without success. We proposed intralesional injection of triamcinolone at 20 mg every 15 days associated with oral clofazimine at 50 mg/day for three months. The lip became normal after four triamcinolone injections. Recent studies have considered MRS a granulomatous disease, and possibly the initial presentation of Crohn's disease in orofacial area of some patients. MRS patients, therefore, should be screened and monitored for gastrointestinal symptoms. Corticosteroid treatment seems to be effective in reducing lip enlargement. We discuss the clinical features of this disease, the treatment, and the importance of corticosteroid therapy in cases of MRS-related facial palsy.
Kidney allograft infarction associated with transplant renal artery stenosis in a COVID-19 kidney transplant recipient
Authors: Ekamol Tantisattamo, Donald C Dafoe, Antoney J Ferrey, Hirohito Ichii, Richard A Lee, Jonathan E Zuckerman, Anthony E Jr Sisk, Ted Farzaneh, Jack Guccione, Nii-Kabu Kabutey, Kamyar Kalantar-Zadeh, Uttam G Reddy
Journal: Clin Nephrol Case Stud (2021)
Keywords: covid-19, sars-cov-2, coronavirus disease 2019, kidney allograft infarction, kidney transplantation, severe acute respiratory syndrome coronavirus 2, thromboembolism, thrombosis, transplant renal artery stenosis
MeSH terms: Case Reports

Kidney allograft infarction is rare, but an urgent condition that requires prompt intervention to avoid allograft loss. Renal artery thrombosis is the leading cause of infarction. Apart from traditional risk factors for thrombosis, emerging SARS-CoV-2 predisposes patients to thrombotic diseases both in arterial and venous vasculatures. We report a case of kidney transplant recipient with known transplant renal artery stenosis (TRAS) status post angioplasty with severe COVID-19, complicated by oliguric acute kidney injury requiring continuous renal replacement therapy (CRRT). She did not have a history of thromboembolic disease. The hospital course was complicated by new-onset atrial and ventricular fibrillation and cardiac arrest requiring multiple rounds of cardiopulmonary resuscitation. She had no signs of renal recovery, and an abdominal CT scan showed evidence of allograft infarcts. She underwent an allograft nephrectomy. Pathology revealed diffuse thrombotic microangiopathy involving glomeruli, arterioles, and arteries associated with diffuse cortical infarction with negative SARS-CoV-2 immunostain and in situ hybridization. This is the first case of kidney allograft infarct with a history of TRAS in a COVID-19 patient. Underlying TRAS and COVID-19-associated thrombosis in this patient are unique and likely play a key role in allograft infarction from arterial thrombosis. Recognizing risk factors and early therapy for allograft infarction may improve transplant outcomes.
Low-cost sensor-integrated 3D-printed personalized prosthetic hands for children with amniotic band syndrome: A case study in sensing pressure distribution on an anatomical human-machine interface (AHMI) using 3D-printed conformal electrode arrays
Authors: Yuxin Tong, Ezgi Kucukdeger, Justin Halper, Ellen Cesewski, Elena Karakozoff, Alexander P Haring, David McIlvain, Manjot Singh, Nikita Khandelwal, Alex Meholic, Sahil Laheri, Akshay Sharma, Blake N Johnson
Journal: PLoS One (2019)
MeSH terms: Amniotic Band Syndrome, Artificial Limbs, Precision Medicine, Printing, Three-Dimensional, User-Computer Interface, Wearable Electronic Devices, Clinical Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Child, Humans, Male

Interfacing anatomically conformal electronic components, such as sensors, with biology is central to the creation of next-generation wearable systems for health care and human augmentation applications. Thus, there is a need to establish computer-aided design and manufacturing methods for producing personalized anatomically conformal systems, such as wearable devices and human-machine interfaces (HMIs). Here, we show that a three-dimensional (3D) scanning and 3D printing process enabled the design and fabrication of a sensor-integrated anatomical human-machine interface (AHMI) in the form of personalized prosthetic hands that contain anatomically conformal electrode arrays for children affected by amniotic band syndrome, a common birth defect. A methodology for identifying optimal scanning parameters was identified based on local and global metrics of registered point cloud data quality. This method identified an optimal rotational angle step size between adjacent 3D scans. The sensitivity of the optimization process to variations in organic shape (i.e., geometry) was examined by testing other anatomical structures, including a foot, an ear, and a porcine kidney. We found that personalization of the prosthetic interface increased the tissue-prosthesis contact area by 408% relative to the non-personalized devices. Conformal 3D printing of carbon nanotube-based polymer inks across the personalized AHMI facilitated the integration of electronic components, specifically, conformal sensor arrays for measuring the pressure distribution across the AHMI (i.e., the tissue-prosthesis interface). We found that the pressure across the AHMI exhibited a non-uniform distribution and became redistributed upon activation of the prosthetic hand's grasping action. Overall, this work shows that the integration of 3D scanning and 3D printing processes offers the ability to design and fabricate wearable systems that contain sensor-integrated AHMIs.
Multifocal musculoskeletal tuberculosis mimicking multiple bone metastases: a case report
Authors: Meiping Ye, Jinwei Huang, Jie Wang, Jianmin Ren, Jianfei Tu, Weibo You, Taohui Zhu
Journal: BMC Infect Dis (2016)
MeSH terms: Mycobacterium tuberculosis / isolation & purification, Tuberculosis, Spinal / diagnosis, Case Reports, Antitubercular Agents / therapeutic use, Bone Neoplasms / diagnosis, DNA, Bacterial / analysis, Diagnosis, Differential, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Mycobacterium tuberculosis / genetics, Polymerase Chain Reaction, Positron-Emission Tomography, Tomography, X-Ray Computed, Tuberculosis, Spinal / drug therapy, Tuberculosis, Spinal / microbiology, Antitubercular Agents, DNA, Bacterial

Background:
The occurrence of non-contiguous, multiple, and remote involvement tuberculous spondylitis is rare. The clinical presentation in patients with multifocal musculoskeletal tuberculosis may closely mimic that in patients with multiple bone metastases, which makes the accurate clinical diagnosis challenging. Herein, we report a multifocal musculoskeletal tuberculosis case that was misdiagnosed for 8 months as multiple bone metastases.
Case presentation:
A 63-year-old male farmer of Chinese Han ethnicity presented to us with pain in left side of the neck, right side of the chest and the back for 10 months without typical tuberculosis symptoms. His past medical history, the CT and fluoroscopy-guided biopsy were negative for tuberculosis. Interferon gamma by T-SPOT was also negative. Radiological findings including CT, MRI and PET-CT suggested that the patient had multiple metastases. Accordingly, the patient was misdiagnosed as having musculoskeletal tumors until a swelling under the right nipple ulcerated. The smear test for acid-fast bacilli and the PCR test for TB-DNA of the pus from the swollen area were both positive, leading to the final correct diagnosis of musculoskeletal tuberculosis.
Conclusion:
The proper diagnosis of musculoskeletal tuberculosis is clinically challenging due to Mycobacterium tuberculosis variants involved and atypical presentations, especially when the lesions are multiple. Our findings indicate that multiple tuberculous spondylitis must be considered in the differential diagnosis of multiple musculoskeletal lesions.
Hyperinflammation in Two Severe Acute Respiratory Syndrome Coronavirus 2-Infected Adolescents Successfully Treated With the Interleukin-1 Inhibitor Anakinra and Glucocorticoids
Authors: Francesca I Calò Carducci, Maria Antonietta De Ioris, Chiara Agrati, Rita Carsetti, Daniela Perrotta, Patrizia D'Argenio, Fabrizio De Benedetti, Stefania Notari, Paolo Rossi, Andrea Campana
Journal: Front Pediatr (2020)
Keywords: covid-19, mis-c, pims-ts, sars-cov-2, anti-inflammatory treatment, coronavirus disease 2019, cytokine storm, pediatric
MeSH terms: Case Reports

Background: In severe acute respiratory syndrome-related coronavirus (SARS-CoV-2) critically ill adults, hyperinflammation plays a key role in disease progression. The clinical manifestations of SARS-CoV-2 infection among children are much less severe compared with adult patients and usually associated with a good prognosis. However, hyperinflammation in SARS-CoV-2-infected pediatric patients has been described as pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 or as Kawasaki-like disease but is still little known, and optimal management has to be defined. The World Health Organization (WHO) on the 15th of May 2020 has developed a preliminary case definition for multisystem inflammatory disorder in children and adolescents with coronavirus disease 2019 (COVID-19) and stated for an urgent need to collect data on this condition. Here, we report two adolescent patients affected by COVID-19 presenting with multisystem inflammatory disorder, 3-4 weeks after the first symptoms of SARS-CoV-2 infection, treated with the interleukin-1 receptor antagonist anakinra and glucocorticoids with good clinical response. Cases: We report two patients chronically ill appearing, with high fever, severe gastrointestinal involvement, and increased biomarkers of inflammation onset 3-4 weeks after paucisymptomatic SARS-CoV-2 infection. They had no lung involvement, but abdominal ultrasound and CT scan showed thickening of the bowel wall. SARS-CoV-2 PCR was positive on ileum biopsy in both patients, whereas it was negative on other common sampled sites. They have been admitted to the pediatric intensive care unit and have been treated with a combination of anakinra 6-8 mg/kg/day i.v. and a standard dose of methylprednisolone 2 mg/kg/day in addition to lopinavir/ritonavir 400 mg q12h and low molecular weight heparin 100 UI/kg q12h with good clinical response.
Life-Threatening Autoimmune Hemolytic Anemia and Idhiopatic Thrombocytopenic Purpura. Successful Selective Splenic Artery Embolization
Authors: Matteo Molica, Fulvio Massaro, Giorgia Annechini, Erminia Baldacci, Gianna Maria D'Elia, Riccardo Rosati, Silvia Maria Trisolini, Paola Volpicelli, Robin Foà, Saveria Capria
Journal: Mediterr J Hematol Infect Dis (2016)
MeSH terms: Case Reports

Selective splenic artery embolization (SSAE) is a nonsurgical intervention characterized by the transcatheter occlusion of the splenic artery and/or its branch vessels using metallic coils or other embolic devices. It has been applied for the management of splenic trauma, hypersplenism with portal hypertension, hereditary spherocytosis, thalassemia and splenic hemangioma. We hereby describe a case of a patient affected by idiopathic thrombocytopenic purpura (ITP) and warm auto-immune hemolytic anemia (AIHA) both resistant to immunosuppressive and biological therapies, not eligible for a surgical intervention because of her critical conditions. She underwent SSAE and achieved a hematologic complete response within a few days without complications. SSAE is a minimally invasive procedure to date not considered a standard option in the management of AIHA and ITP. However, following the progressive improvement of the techniques, its indications have been extended, with a reduction in morbidity and mortality compared to splenectomy in patients with critical clinical conditions. SSAE was a lifesaving therapeutic approach for our patient and it may represent a real alternative for the treatment of resistant AIHA and ITP patients not eligible for splenectomy.
Changes in caries risk and activity of a 9-year-old patient with niemann-pick disease type C
Authors: Késsia Suênia Fidelis Mesquita-Guimarães, Andiara De Rossi, Aldevina Campos Freitas, Paulo Nelson-Filho, Raquel Assed da Silva, Alexandra Mussolino de Queiroz
Journal: Case Rep Dent (2015)

Objective. This case report describes the changes in caries risk and activity and dental treatment of a 9-year-old patient who presented with signs and symptoms of Niemann-Pick disease type C (NPC). Treatment. The preventive dental treatment included instructions to caregivers for oral hygiene and diet. A calcium hydroxide pulpotomy and restorative dental treatments were performed in a dental office with desensitization techniques and behavioral management. The patient was attended every 3 months for the control of dental plaque biofilm, for topical fluoride application, and for observing the pulpotomized tooth. Results. The bacterial plaque biofilm was being adequately controlled by the caregiver. After 2 years, the clinical and radiographic examination of the pulpotomized tooth showed the absence of internal root resorption and bone rarefaction, and clinical examination showed tooth sensitivity, dental pain, and gingival swelling. Conclusion. The pulpotomy prevented clinical and radiographic success. Dentists must be aware of and be able to identify systemic and local aspects associated with caries risk of children with NPC disease. Furthermore, dentists must employ stringent preventive measures and provide instructions to caregivers to reduce caries risk.
Fractional order SEIQRD epidemic model of Covid-19: A case study of Italy
Authors: Subrata Paul, Animesh Mahata, Supriya Mukherjee, Prakash Chandra Mali, Banamali Roy
Journal: PLoS One (2023)
MeSH terms: COVID-19 / epidemiology, Epidemics, Case Reports, Computer Simulation, Epidemiological Models, Humans, Italy / epidemiology

The fractional order SEIQRD compartmental model of COVID-19 is explored in this manuscript with six different categories in the Caputo approach. A few findings for the new model's existence and uniqueness criterion, as well as non-negativity and boundedness of the solution, have been established. When RCovid19<1 at infection-free equilibrium, we prove that the system is locally asymptotically stable. We also observed that RCovid 19<1, the system is globally asymptotically stable in the absence of disease. The main objective of this study is to investigate the COVID-19 transmission dynamics in Italy, in which the first case of Coronavirus infection 2019 (COVID-19) was identified on January 31st in 2020. We used the fractional order SEIQRD compartmental model in a fractional order framework to account for the uncertainty caused by the lack of information regarding the Coronavirus (COVID-19). The Routh-Hurwitz consistency criteria and La-Salle invariant principle are used to analyze the dynamics of the equilibrium. In addition, the fractional-order Taylor's approach is utilized to approximate the solution to the proposed model. The model's validity is demonstrated by comparing real-world data with simulation outcomes. This study considered the consequences of wearing face masks, and it was discovered that consistent use of face masks can help reduce the propagation of the COVID-19 disease.
Conjunctival inclusion cyst following repair of tube erosion in a child with aphakic glaucoma, leading to endophthalmitis
Authors: Avik Kumar Roy, Sirisha Senthil
Journal: GMS Ophthalmol Cases (2015)
Keywords: ahmed glaucoma valve, conjunctival inclusion cyst, tube erosion
MeSH terms: Case Reports

Introduction:
Glaucoma in aphakia is a major long term complication following congenital cataract surgery. Implantation of glaucoma drainage device provides an effective approach to manage refractory paediatric glaucoma. However implant surgery in young individuals is not free of complications. The prompt detection and management of tube erosion is of utmost importance to prevent devastating sequel of endophthalmitis. Implantation cyst following repair of tube erosion has not been reported so far. This case illustrates the rare occurrence of inclusion cyst following repair of tube erosion, the possible causes and its consequences.
Case description:
A 2-year-old child with aphakia developed intractable glaucoma. Following a failed glaucoma filtering surgery he underwent sequential Ahmed Glaucoma Valve implantation in both the eyes. Six weeks following right eye surgery, the child presented with conjunctival erosion overlying the tube, which was treated with scleral patch graft and conjunctival advancement. One month after the repair of tube erosion, the child presented with implantation cyst under the scleral patch graft, which was treated by drainage with a 29G needle. The child presented with endophthalmitis of his right eye following an episode of bilateral conjunctivitis. This was managed by an emergency pars plana vitrectomy, intraocular antibiotics and tube excision. At the last follow up visit, the IOP was 20 mmHg with 2 topical antiglaucoma medications in the right eye following a trans scleral photocoagulation.
Discussion:
Lifelong careful follow-up of paediatric eyes with implant surgery is mandatory to look for complication such as tube erosion. It is important to place additional sutures to secure the patch graft during implantation of glaucoma drainage devices in children to prevent graft displacement and consequent tube erosion. During repair of tube erosion, it is crucial to remove all the conjunctival epithelium around the tube, thus not to incorporate epithelial tissue within the surgical wound.
Detection and Intervention of Clinically Masquerading Inferior Mesenteric Artery AVMs
Authors: Amir Pakray, Nolan Hayden, Farnoosh Sokhandon, Johnathan Olsen
Journal: Case Rep Radiol (2021)
MeSH terms: Case Reports

We demonstrate a rare case of inferior mesenteric artery arteriovenous malformations leading to ischemic colitis in a 76-year-old female. Our patient presented with three months of nausea, vomiting, and diarrhea. Colonoscopy displayed diffuse mucosal vascular congestion while CTA and MRA displayed AVMs in the region of the IMA; however, cohesive clinical agreement on AVM from multiple specialties was difficult given its rare occurrence and nonspecific clinical, histopathologic, and directly visualized findings. The three noted dominant AVMs were eventually selected with coil and liquid embolization with successful cessation of symptoms and no major complications. Our discussion focuses on intervention and stressing the importance of radiologic findings, as IMA AVMs, rarely present as ischemic colitis and therefore can clinically masquerade as other etiologies.
An unusual Spigelian hernia involving the appendix: a case report
Authors: Sarah C Thomasset, Eduardo Villatoro, Sarah Wood, Alice Martin, Kelly Finlay, Jane E Patterson
Journal: Cases J (2010)

Introduction:
Spigelian herniae are uncommon and frequently pose a diagnostic challenge.
Case presentation:
We report the case of a 71-year-old man in whom an ischaemic appendix was found within the sac of a Spigelian hernia during emergency repair.
Conclusions:
There are very few reported cases in which an appendix has been found within a Spigelian hernia, in the absence of inflammatory bowel disease. An awareness of the range of viscera which may be encountered in Spigelian herniae is important for safe repair.