OpenMed/multicare-articles huggingface dataset:
Mesenteric Ischemia and Myocardial Infarction Associated with Atrial Fibrillation
Authors: Liting Cheng, Yongquan Wu
Journal: Case Rep Cardiol (2018)
MeSH terms: Case Reports

Atrial fibrillation is a common disease correlated with embolism incidents. However, there is lack of report on atrial fibrillation causing myocardial infarction and mesenteric ischemia at the same time. Our patient is a 69-year-old woman who had undergone thoracic surgery a month before presented to our hospital with newly discovered atrial fibrillation, abdominal pain, and ST-elevated myocardial infarction. This is a rare case that atrial fibrillation took place one month after surgery and caused embolism incidents in both coronary artery and mesenteric artery.
Successful treatment of extensively drug-resistant Acinetobacter baumannii ventriculitis with polymyxin B and tigecycline- a case report
Authors: Wei Guo, Shao-Chun Guo, Min Li, Li-Hong Li, Yan Qu
Journal: Antimicrob Resist Infect Control (2018)
Keywords: acinetobacter baumannii, intraventricular therapy, multidrug resistance, polymyxin b, ventriculitis
MeSH terms: Acinetobacter baumannii / drug effects, Cerebral Ventriculitis / drug therapy, Drug Resistance, Multiple, Bacterial / drug effects, Polymyxin B / therapeutic use, Tigecycline / therapeutic use, Case Reports, Acinetobacter baumannii / pathogenicity, Administration, Intravenous, Anti-Bacterial Agents / administration & dosage, Anti-Bacterial Agents / therapeutic use, Blood-Brain Barrier, Brain Injuries / complications, Brain Injuries / diagnostic imaging, Cerebral Ventriculitis / diagnostic imaging, Cerebral Ventriculitis / microbiology, China, Drug Combinations, Humans, Male, Meningitis, Bacterial / drug therapy, Middle Aged, Polymyxin B / administration & dosage, Tigecycline / administration & dosage, Tomography, X-Ray Computed, Anti-Bacterial Agents, Drug Combinations, Tigecycline, Polymyxin B

Background:

Acinetobacter baumannii nosocomial ventriculitis/meningitis, especially those due to drug-resistant strains, has substantially increased over recent years. However, limited therapeutic options exist for the Acinetobacter baumannii ventriculitis/meningitis because of the poor penetration rate of most antibiotics through the blood-brain barrier.
Case presentation:
A 57-year-old male patient developed ventriculitis from an extensively drug-resistant strain of Acinetobacter baumannii after the decompressive craniectomy for severe traumatic brain injury. The patient was successfully treated with intraventricular and intravenous polymyxin B together with intravenous tigecycline.
Conclusions:
The case illustrates intraventricular polymyxin B can be a therapeutic option against extensively drug-resistant Acinetobacter baumannii ventriculitis.
Small Bowel Obstruction due to Migrated Intragastric Balloon: A Case Report and Literature Review
Authors: Min Yien Tan, Kar Yin Fok, Huong Nguyen, Senarath Edirimanne, Michael Devadas
Journal: Case Rep Surg (2022)
MeSH terms: Case Reports

Introduction:
With the rising rate of obesity world-wide, there are increasing weight loss options including operative and non-operative techniques. Endoscopic intragastric balloons (IGB) have gained popularity since its inception three decades ago and is viewed as a less invasive alternative to bariatric surgery. However, complications, though rare and probably under-reported, can be associated with significant morbidity and mortality. Case Presentation. We present the case of a 44-year-old woman who presented with a two-day history of upper abdominal pain, nausea, and obstipation, on the background of a Spatz3™ Balloon (Spatz FGIA, Great Neck, NY, USA) endoscopically placed seven months prior. Computed tomography scan confirmed small bowel obstruction due to a migrated IGB, requiring laparotomy and enterotomy for retrieval.
Conclusion:
With the development of new types of IGB and increasing usage, it is important to monitor for issues and complications.
Clinical Relevance of Pharmacogenetics in Serotonin Syndrome
Authors: Dehuti Pandya, My Tran, Monica Verduzco-Gutierrez
Journal: Case Rep Psychiatry (2020)
MeSH terms: Case Reports

Serotonin syndrome is a predictable life-threatening condition that is caused by serotonergic stimulation of the central and peripheral nervous systems. A patient's genetic profile can amplify exposure risk as many serotonergic drugs are metabolized by CYP450 enzymes, and these enzymes may be altered in functionality. We report a case of an elderly man who presented with serotonin syndrome after a dose change in valproic acid 5 weeks prior. His medication list consisted of low-dose serotonergic agents, which is unusual as most cases of serotonin syndrome involve higher doses. A review of his pharmacogenetic profile is presented to retrospectively evaluate the additive risk for serotonin syndrome and implications on resuming serotonergic agents.
The several faces of the medicalization of birth. Italy and its peculiarities
Authors: Elena Spina
Journal: Front Sociol (2023)
Keywords: european comparison, childbirth policies, maternity model of care, medicalization of pregnancy and birth, regional differences in italy

Background:
Medical-scientific advances in maternal care gradually improved the health of mothers and new-borns. However, this has contributed to increasing levels of medicalization, defined as the overuse of medical interventions even in low-risk pregnancies and childbirths. In Italy pregnancy and birth still appear to be rather medicalized than in the rest of Europe. Moreover, the uneven distribution of these practice over the territory appears to be evident. The purpose of this article is to both highlight and explain the Italian peculiarity in terms of high medicalization of childbirth and its territorial variability.
Theoretical framework:
The extensive literature on medicalization of childbirth was systematized by some scholars who use childbirth as a case study to distinguish four meanings of medicalization, by classifying them into two generations of theories. Alongside this literature several studies attempted to interpret differences in maternity model of care showing the important role played by path dependence.
Results:
In the European scenario, Italy stands out for its high percentage of cesarean sections, but also for its excessive recourse to antenatal visits during pregnancy and the application of interventions during labor and vaginal births. Going into regional detail, however, Italian situation appears rather uneven: relevant differences emerge in relation to medicalization of both pregnancy and birth.
Discussion:
The article explores the possibility that areas whit different sociocultural, economic, political and institutional background may have introjected different meanings of medicalization, thus reproducing different maternity models of care. In fact, the simultaneous presence, in Italy, of four different meanings of medicalization seems to be rooted. Even with some similar traits, different conditions and situations emerge in different geographical areas, leading to the prevalence of one meaning rather than another and resulting on different outcomes in terms of medicalization.
Conclusion:
The data presented in this article seem to deny the existence of a national maternity model of care and. On the contrary, they confirm the idea that medicalization is not necessarily linked to the different health conditions of mothers in different geographical areas and that a path dependent variable is able to explain it.
A Case of Urethral Diverticulum with Surgical Repair Using Cadaveric Pericardial Tissue
Authors: Loren Custer, Morris Jessop, Stanley Zaslau, Robert Shapiro
Journal: Case Rep Urol (2018)
MeSH terms: Case Reports

A urethral diverticulum is a relatively uncommon finding. The estimated prevalence is approximately 1-5% in the general population. While the definitive treatment is surgical correction, there are limited studies guiding the best approach to repair. This is the case of a 48-year-old female who initially presented with vaginal discharge, dysuria, and dyspareunia. MRI revealed the diagnosis of suspected urethral diverticulum. The patient was treated with surgical correction with the aid of needle localization prior to the procedure. After the diverticulum was excised, the resulting defect in the urethra was successfully closed with cadaveric pericardial tissue. A urethral diverticulum should be considered in the differential diagnosis when a patient presents with symptoms such as recurrent urinary tract infections (UTIs) vaginal mass, dysuria, dyspareunia, or vaginal discharge. The use of cadaveric tissue augments the surgical technique for repair.
MRI of a recurrent adenoid cystic carcinoma of the trachea, treated with fast neutron therapy
Authors: Laura Sweeney, Frederik Vernimmen, Sandra Sinske
Journal: BJR Case Rep (2016)
MeSH terms: Case Reports

Adenoid cystic carcinoma (ACC) of the trachea is a rare tumour, which responds well to high linear energy transfer radiation, such as neutron therapy. Both CT and MRI are useful for its diagnosis, with MRI being superior at determining the extent of disease and perineural involvement. Identification of these disease characteristics with MRI helps to determine lesion resectability and decide on the most appropriate treatment strategies. MRI is also useful in the differentiation of post-radiation change from disease recurrence, with post-radiation change displaying low T 2 signal intensity compared with tumour recurrence displaying intermediate to high T 2 signal intensity. Furthermore, MR diffusion-weighted imaging can be useful in the distinction between the two. We present a case of tracheal ACC treated with fast neutron therapy and followed with MRI.
Irreversible anterior ischemic optic neuropathy complicating interferon alpha and ribaverin therapy
Authors: Hassan Seddik, Mouna Tamzaourte, Fadoua Rouibaa, Maha Fadlouallah, Ahmed Benkirane
Journal: Int J Hepatol (2011)
MeSH terms: Case Reports

Ophthalmologic complications with interferon therapy are rare and usually reversible. The anterior ischemic optic neuropathy is an uncommon complication of interferon treatment. A case of irreversible anterior ischemic optic neuropathy complicating interferon therapy for chronic hepatitis C is reported. We suggest that periodic ophthalmological examinations, including visual acuity and fundus examinations, should be performed to patients with high risk of ocular complications after starting and during treatment. We also suggest that an ophthalmologist would be able to detect these complications. Antiviral treatment should be stopped immediately if severe ophthalmologic complications occur.
A Rare Case of Nonsyndromic Generalized Radiculomegaly with a Literature Review
Authors: Mohammad Al-Obaida
Journal: Case Rep Dent (2020)
MeSH terms: Case Reports

Radiculomegaly is a rare condition involving elongated tooth roots. This condition has significant clinical implications and has been associated with syndromes such as oculofaciocardiodental syndrome. However, only a few nonsyndromic cases of radiculomegaly have been reported. Here, we report a case of nonsyndromic radiculomegaly in a Saudi individual. A subsequent review of the literature suggests endodontic management modalities for individuals with the dental findings demonstrated in the present case.
Non-hepatitis-associated mixed cryoglobulinemia with polyclonal plasma cells disease and alcoholic cirrhosis: A rare case report
Authors: Jiao Luo, Cheng Liu, Qing-Jian Lv, Ting He, Xing Qiang, Yi Li, Qi-Mi Huang, Jia-Lin He
Journal: Front Med (Lausanne) (2023)
Keywords: alcoholic liver cirrhosis, cryoglobulins, mixed cryoglobulinemia, polyclonal plasma cells disease, renal impairment
MeSH terms: Case Reports

Mixed cryoglobulinemia refers to the serum presence of a variety of cryoglobulins, which are defined as immunoglobulins that precipitate at temperatures of < 37°C. The most common cause of mixed cryoglobulinemia is hepatitis C virus (HCV), while other infections, including hepatitis B virus (HBV) and HIV infections, and lymphoproliferative and autoimmune disorders have also been associated with the disease. We reported a rare case of type II-III mixed cryoglobulinemia caused by alcoholic cirrhosis. We need to increase the awareness of and facilitate the early identification of mixed cryoglobulinemia in our clinical study when encountering a patient with liver cirrhosis combined with renal impairment so that treatment can begin early to improve the success rate of therapy and reduce the fatality rate in a potentially life-saving therapy.
Two Cases of Catastrophic AAA Rupture in Young Women with Systemic Lupus Erythematosus
Authors: David Noorvash, Kevin King, Meera Gebrael
Journal: Case Rep Emerg Med (2018)
MeSH terms: Case Reports

We present two cases of young women with a past medical history significant for systemic lupus erythematosus (SLE), who presented to the Emergency Department with a ruptured abdominal aortic aneurysm (AAA). These cases are of particular interest because the patients did not fit the typical demographic for patients who present with a ruptured AAA. Based on these cases and a review of the relevant literature, ED providers should maintain a higher index of suspicion for AAA rupture in patients with autoimmune diseases, especially SLE.
Five cases of skin desquamation due to bevacizumab combined with docetaxel-carboplatin in ovarian cancer
Authors: Megumi Tokunaga, Shuichi Nawata, Takayuki Komoto, Rei Mathuura, Daisuke Ichikura, Toru Watanabe, Tadanori Sasaki
Journal: Int Cancer Conf J (2022)
Keywords: bevacizumab, docetaxel-carboplatin, ovarian cancer, skin desquamation
MeSH terms: Case Reports

The standard of care for ovarian cancer chemotherapy is paclitaxel-carboplatin. In Stage III and Stage IV patients, the addition of bevacizumab has been reported to be effective, and bevacizumab combined with paclitaxel-carboplatin and bevacizumab combined with docetaxel-carboplatin are used. Patients who received bevacizumab combined with docetaxel-carboplatin experienced a high incidence of skin hardening followed by peeling. In patients treated with bevacizumab combined with docetaxel-carboplatin, we experienced a high incidence of post-sclerotic peeling of the skin, a symptom that is rarely seen with paclitaxel-carboplatin (TC), docetaxel-carboplatin (DC), or bevacizumab combined with paclitaxel-carboplatin, and has been reported in a few cases. Therefore, we investigated the actual situation of skin desquamation caused by bevacizumab combined with docetaxel-carboplatin. Thirty-one patients were included in the study, and their age (mean ± SD) was 62.9 ± 9.0. The breakdown of treatment was as follows: TC in nine patients, bevacizumab combined with paclitaxel-carboplatin in ten patients, DC in six patients, and bevacizumab combined with docetaxel-carboplatin in six patients. No number of patients with TC or bevacizumab combined with paclitaxel-carboplatin showed skin desquamation. One for DC, and five for bevacizumab combined with docetaxel-carboplatin. The five patients treated with bevacizumab combined with docetaxel-carboplatin improved with topical steroids and moisturizers, but symptoms repeatedly appeared after each course. Skin desquamation was more frequent in bevacizumab combined with docetaxel-carboplatin.
Unilateral proptosis and blindness caused by meningioma in a patient treated with cyproterone acetate
Authors: Celine Sys, Philippe Kestelyn
Journal: GMS Ophthalmol Cases (2015)
MeSH terms: Case Reports

Cyproterone has antiandrogenic, antigonadotropic, and progestagenic activity. High-dose preparations are used for treatment of prostate cancer and for treatment of hypersexuality. We describe a patient who was referred to our clinic with slowly progressive unilateral proptosis and blindness of the left eye. He had been treated with high-dose cyproterone actate (CPA) for 23 years. An obvious proptosis and exodeviation of his left eye was noted on ophthalmic examination. Fundoscopy showed left optic atrophy. The literature suggests a link between long-term high-dose exogenous progesterone agonist exposure and the progression and/or development of meningioma. MRI of the brain was performed and revealed multiple meningiomas. One large meningioma located in the anterior temporal lobe extended into the left orbit and caused the proptosis and blindness. Treatment with CPA was stopped and follow-up imaging 11 months later showed a significant decrease in size of the largest meningiomas.
Subdiaphragmatic Renal Ectopia: Case Report and Review of the Literature
Authors: Eleftherios Zolotas, Rajesh G Krishnan
Journal: Case Rep Nephrol (2016)

Background. We report the case of a male infant whose right kidney migrated to an ectopic position after birth. The migration of a kidney in postnatal life without any symptoms has not been reported in literature so far. Case Presentation. In a series of antenatal and the first postnatal ultrasound scans, the right kidney was normally located within the right renal fossa. During the first 3 months of life, the kidney migrated to a subdiaphragmatic position. This was confirmed on MRI scan. The infant was asymptomatic with normal renal function and blood pressure. Conclusion. Postnatal migration of a kidney has been described in cases of diaphragmatic hernia or nephroptosis. In this report, we describe a case of kidney migration where there were no underlying anatomical defects to provide an explanation for the kidney migration. This is the first report in literature of a case of postnatal migration of a kidney.
Simultaneous closed rupture of flexor digitorum superficialis and flexor digitorum profundus tendons in the middle finger: a case report
Authors: Robert W Jordan, Naeil Lotfi, Gunaratnam Shyamalan
Journal: Case Reports Plast Surg Hand Surg (2015)
Keywords: flexor tendon, hand, hand finger, trauma
MeSH terms: Case Reports

A 20-year-old man suffered a closed rupture of both flexor tendons in the middle finger while playing rugby. Primary repair of the flexor digitorum profundus and excision of the flexor digitorum superficialis was performed. At follow up he reported a Disabilities of the Arm, Shoulder and Hand score of 0 and unrestricted return to activities.
Exogenous re-infection by a novel Streptococcus pneumoniae serotype 14 as a cause of recurrent meningitis in a child from The Gambia
Authors: Martin Antonio, Claire Oluwalana, Ousman Secka, Tumani Corrah, Stephen Howie, Richard A Adegbola
Journal: Ann Clin Microbiol Antimicrob (2009)
MeSH terms: Meningitis, Pneumococcal / microbiology, Sequence Analysis, DNA, Streptococcus pneumoniae / classification, Streptococcus pneumoniae / isolation & purification, Case Reports, Research Support, Non-U.S. Gov't, Bacterial Typing Techniques, Female, Gambia, Humans, Infant, Meningitis, Pneumococcal / prevention & control, Recurrence, Serotyping, Streptococcus pneumoniae / genetics, Streptococcus pneumoniae / pathogenicity

We report a case of an infant who experienced exogenous re-infection of Streptococcus pneumoniae serotype 14 as a cause of recurrent meningitis after apparently successful antibiotic treatment with ceftriaxone. eBURST analysis revealed that isolates from the two episodes of meningitis belonged to hypervirulent ST63 and ST3321 clonal complexes respectively.
Abdominal wall recurrence of a gastrointestinal stromal tumor: case report
Authors: Hajar Hachim, Anass Mohammed Majbar, Mouna Alaoui, Mohamed Raiss, Farid Sabbah, Abdelmalek Hrora, Mohamed Ahallat
Journal: Springerplus (2015)
Keywords: gastrointestinal stromal tumor, laparoscopic surgery, neoplasm recurrence

Introduction:
The gastrointestinal stromal tumors (GIST) are mesenchymal tumors, most commonly affecting the stomach and small bowel. Only few cases of port-site recurrence after laparoscopic treatment have been reported. We herein report the case of a parietal recurrence on the extraction incision site, 7 years after laparoscopic surgery for small bowel GIST.
Case report:
A 47 years-old female patient was hospitalized in November 2007 for isolated pelvic pain. CT scan showed an intestinal tumor with a benign aspect measuring 50 mm. A laparoscopy-assisted resection was performed. Surgical exploration found a 7 cm small bowel tumor. It was extracted through a supra-pubic transversal incision without a wound protector and then resected. Histologic analysis revealed an intestinal GIST with high aggressive potential (five mitosis per field), with CD117 positive at the immunohistochemical examination. The patient had no adjuvant chemotherapy. Seven years later, the patient was readmitted for an abdominal mass at the site of the supra-pubic scar. Abdomino-pelvic CT scan showed a 10 × 7.5 cm solid mass of the abdominal wall. Percutaneous biopsies were done and the pathological analysis revealed a mesenchymal-cell tumor, positive to CD117 and DOG1 at the immunohistochemical examination. Final diagnosis was abdominal wall recurrence of GIST secondary to tumor-contamination during the first surgery.
Conclusion:
Abdominal wall recurrence of GIST after laparoscopic surgery is rarely reported. This complication should be avoided with preventive measures such as the use of extraction bags or wound protectors.
Strawberry skull in Edwards syndrome
Authors: Umesh Shriniwas Mudaliyar, Sneha Umesh Mudaliyar
Journal: BJR Case Rep (2017)
MeSH terms: Case Reports

The trisomy 18 syndrome, also known as Edwards syndrome, is the second most common disorder after trisomy 21 (Down's syndrome). It is a chromosomal disorder due to the presence of an extra chromosome 18, which could be either full, mosaic trisomy or partial trisomy 18q. The live born prevalence is estimated as 1/3,000 -1/8,000, but the overall prevalence is higher 1/2500-1/2600 due to the high frequency of foetal loss and pregnancy termination after the prenatal diagnosis. We are presenting a case of Edwards syndrome diagnosed during routine antenatal scan.
A giant dumbbell shaped vesico-prostatic urethral calculus: a case report and review of literature
Authors: Vinod Kumar Prabhuswamy, Rahul Tiwari, Ramakrishnan Krishnamoorthy
Journal: Case Rep Urol (2013)

Calculi in the urethra are an uncommon entity. Giant calculi in prostatic urethra are extremely rare. The decision about treatment strategy of calculi depends upon the size, shape, and position of the calculus and the status of the urethra. If the stone is large and immovable, it may be extracted via the perineal or the suprapubic approach. In most of the previous reported cases, giant calculi were extracted via the transvesical approach and external urethrotomy. A 38-year-old male patient presented with complaints of lower urinary tract symptoms. Further investigations showed a giant urethral calculus secondary to stricture of bulbo-membranous part of the urethra. Surgical removal of calculus was done via transvesical approach. Two calculi were found and extracted. One was a huge dumbbell calculus and the other was a smaller round calculus. This case was reported because of the rare size and the dumbbell nature of the stone. Giant urethral calculi are better managed by open surgery.
Immunocheckpoint Inhibitor- (Nivolumab-) Associated Hypereosinophilia in Non-Small-Cell Lung Carcinoma
Authors: Navdeep Singh, Sandeep Singh Lubana, George Constantinou, Andrea N Leaf
Journal: Case Rep Oncol Med (2020)
MeSH terms: Case Reports

Immunocheckpoint inhibitor (ICI) therapy has provided significant clinical improvements in the treatment of several malignancies. The purpose of this report is to increase awareness of hypereosinophilia associated with checkpoint inhibitors, a topic that has been rarely reported. Hypereosinophilia may need to be addressed especially if eosinophil counts increase to levels where hypereosinophilic visceral complications can occur. We are presenting a case of a 57-year-old male with hypereosinophilia that was seen in the setting of progression of metastatic non-small-cell lung cancer during and after nivolumab treatment.