OpenMed/multicare-articles huggingface dataset:
Artistic Skills Recovery and Compensation in Visual Artists after Stroke
Authors: Eugen Bogdan Petcu, Katherine Sherwood, Aurel Popa-Wagner, Ana Maria Buga, Lanfranco Aceti, Rodica Ileana Miroiu
Journal: Front Neurol (2016)
Keywords: artistic skills recovery, compensation, functional magnetic resonance imaging, molecular, parietal lobe, prefrontal lobe, stroke
MeSH terms: Review

Background:
Art is a characteristic of mankind, which requires superior central nervous processing and integration of motor functions with visual information. At the present time, a significant amount of information related to neurobiological basis of artistic creation has been derived from neuro-radiological cognitive studies, which have revealed that subsequent to tissue destruction, the artists continue to create art. The current study aims to review the most important cases of visual artists with stroke and to discuss artistic skills recovery and compensation as well as artistic style after stroke.
Methods:
The role of various central nervous system regions in artistic creation was reviewed on the basis of previously published functional studies. Our PubMed search (1995-2015) has identified 10 famous artists with right cerebral stroke as well as 5 with left cerebral stroke who survived and continued to create art after stroke. As the artists included in this review lived at various times during the twentieth century and in different countries, clinical information related to their case was limited. However, it appears that artistic skills recovery and compensation appear within days after stroke. Some of the artists would subsequently change their artistic style. All these elements have been evaluated within the context of specific clinical cases.
Conclusion:
The poststroke artistic skills recovery and compensation with development of a new style or the opposite, regaining the previous prestroke style, represents a significant element of clinical importance in medical rehabilitation as well as neuroesthetics, which requires further evaluation. At the present time, the molecular mechanisms of artistic creation are poorly understood, and more standardized clinical and experimental studies are needed.
Low prevalence of Cfr-mediated linezolid resistance among methicillin-resistant Staphylococcus aureus in a Spanish hospital: case report on linezolid resistance acquired during linezolid therapy
Authors: Josep M Sierra, Mariana Camoez, Fe Tubau, Oriol Gasch, Miquel Pujol, Rogelio Martin, M Angeles Domínguez
Journal: PLoS One (2013)
MeSH terms: Acetamides / therapeutic use, Anti-Bacterial Agents / therapeutic use, Bacterial Proteins / metabolism, Methicillin-Resistant Staphylococcus aureus / drug effects, Methicillin-Resistant Staphylococcus aureus / isolation & purification, Oxazolidinones / therapeutic use, Staphylococcal Infections / drug therapy, Case Reports, Research Support, Non-U.S. Gov't, Aged, Drug Resistance, Multiple, Bacterial, Hospitals, Humans, Linezolid, Male, Methicillin / therapeutic use, Methicillin-Resistant Staphylococcus aureus / metabolism, Microbial Sensitivity Tests, Spain, Staphylococcal Infections / microbiology, Acetamides, Anti-Bacterial Agents, Bacterial Proteins, CFR protein, Staphylococcus aureus, Oxazolidinones, Linezolid, Methicillin

Linezolid is an effective antimicrobial agent to treat methicillin-resistant Staphylococcus aureus (MRSA). Resistance to linezolid due to the cfr gene is described worldwide. The present study aimed to analyze the prevalence of the cfr-mediated linezolid resistance among MRSA clinical isolates in our area. A very low prevalence of cfr mediated linezolid resistance was found: only one bacteremic isolate out of 2 215 screened isolates. The only linezolid resistant isolate arose in a patient, previously colonized by MRSA, following linezolid therapy. Despite the low rate of resistance in our area, ongoing surveillance is advisable to avoid the spread of linezolid resistance.
Scrotal metastases from colorectal carcinoma: a case report
Authors: Doireann M McWeeney, Sean T Martin, Ronan S Ryan, Iqdam N Tobbia, Paul P Donnellan, Kevin M Barry
Journal: Cases J (2009)

A 72-year-old man presented with a two month history of rectal bleeding. Colonoscopy demonstrated synchronous lesions at 3 cm and 40 cm with histological analysis confirming synchronous adenocarcinomata. He developed bilobar hepatic metastases while undergoing neoadjuvant chemoradiotherapy. Treatment was complicated by Fournier's gangrene of the right hemiscrotum which required surgical debridement. Eight months later he re-presented with an ulcerating lesion on the right hemiscrotum. An en-bloc resection of the ulcerating scrotal lesion and underlying testis was performed. Immunohistological analysis revealed metastatic adenocarcinoma of large bowel origin. Colorectal metastasis to the urogenital tract is rare and here we report a case of rectal carcinoma metastasizing to scrotal skin.
Ingestion and pharyngeal trauma causing secondary retropharyngeal abscess in five adult patients
Authors: Sudhir B Sharma, Paul Hong
Journal: Case Rep Emerg Med (2012)

Retropharyngeal abscess most commonly occurs in children. When present in adults the clinical features may not be typical, and associated immunosuppression or local trauma can be part of the presentation. We present a case series of five adult patients who developed foreign body ingestion trauma associated retropharyngeal abscess. The unusual pearls of each case, along with their outcomes, are discussed. Pertinent information for the emergency medicine physician regarding retropharyngeal abscess is presented as well.
A Case Report of COVID-19 in New Orleans, Louisiana: Highlighting the Complexities of Prognostication in a Critically Ill Patient
Authors: Zachary I Lerner, Rebecca V Burke, Jonathan McCall, Alexandra Leigh, Marcia Glass
Journal: Palliat Med Rep (2020)
Keywords: covid-19, intensive care, palliative care, prognostication
MeSH terms: Case Reports

Palliative care teams and intensive care teams have experience providing goals-of-care guidance for critically ill patients and families. Critical coronavirus disease 2019 (COVID-19) infection is defined as infection requiring intensive care unit care, respiratory support, and often multiorgan involvement. This case presents a 53-year-old critically ill COVID-19 patient in multisystem organ failure who appeared hours from death despite best medical efforts. Comfort-focused care and compassionate extubation were offered after all medical teams felt near certain that death was imminent. Overnight, while options were being considered by the family, the patient began to markedly improve hemodynamically and was extubated several days later. Weeks later, the patient survived the hospital stay and was discharged to rehabilitation. After rehabilitation he returned home, able to walk, communicate freely, and independently perform all activities of daily living. Dialysis was no longer necessary and was stopped. The challenges of assisting in goals-of-care conversations for patients with serious COVID-19 infection are discussed.
A Case of Cannabinoid Hyperemesis Syndrome and Acute Kidney Injury: A Review of the Literature
Authors: Shannay E Bellamy, Brian Loor, Maria Gutierrez-Castillo
Journal: Cureus (2023)
Keywords: cannabinoid, cannabinoid hyperemesis syndrome, cannabis use, hyperemesis, nausea and vomiting
MeSH terms: Case Reports

Cannabis is a commonly used illicit drug worldwide with many noted adverse effects and medical properties. It has been previously used in medicine for the management of chemotherapy-induced nausea and vomiting. The chronic use of cannabis is well-known to be associated with psychological and cognitive adverse effects, however, cannabinoid hyperemesis syndrome is a less commonly recognized complication of chronic long-term use of cannabis, though it does not occur in the majority of chronic cannabis users. Here we present the case of a 42-year-old male who presented with classical clinical features of cannabinoid hyperemesis syndrome.
Case report: Emphysematous cystitis due to Escherichia coli infection with the extension of gas into multiple locations in two non-diabetic dogs: a computed tomographic diagnosis and successful management
Authors: Eun-Ji Lee, Jeong-Min Lee, Jin-Young Kim, Tae-Sung Hwang, Kun-Ho Song, Joong-Hyun Song
Journal: Front Vet Sci (2023)
Keywords: escherichia coli, dog, emphysematous cystitis, ischiorectal fossa, urinary tract infection
MeSH terms: Case Reports

Emphysematous cystitis is an extremely rare, complicated urinary tract infection with the presence of gas in the bladder wall and lumen caused by gas-producing bacterial infections. A 7-year-old spayed female pomeranian dog was presented with a 3-day history of hematuria and pollakiuria (case 1), and a 9-year-old spayed female jindo dog was presented with a 4-day history of intermittent hematuria (case 2). Imaging modalities, including radiography, ultrasonography, and computed tomography, and bacterial culture tests were used for the diagnosis. Emphysematous cystitis due to Escherichia coli infection with the extension of gas into multiple locations was identified in both cases. Based on the results of antibiotic susceptibility testing, systemic antibiotics were initiated. Both animals had an excellent response to antibiotic treatment, and the clinical signs of the gas collection were completely resolved within ~1 month after treatment initiation. This response was sustained without recurrence in the follow-up period. This case report describes clinical details of extremely rare canine cases of emphysematous cystitis with the extension of gas into multiple locations and evaluates the clinical efficacy of antibiotic therapy.
Functional extra-adrenal paraganglioma of the retroperitoneum giving thoracolumbar spine metastases after a five-year disease-free follow-up: a rare malignant condition with challenging management
Authors: Stylianos Kapetanakis, Danai Chourmouzi, Grigorios Gkasdaris, Vasileios Katsaridis, Eleftherios Eleftheriadis, Panagiotis Givissis
Journal: Pan Afr Med J (2017)
Keywords: paraganglioma, metastasis, retroperitoneum, vertebral
MeSH terms: Paraganglioma, Extra-Adrenal / pathology, Retroperitoneal Neoplasms / pathology, Spinal Neoplasms / secondary, Case Reports, Follow-Up Studies, Humans, Lumbar Vertebrae, Male, Middle Aged, Paraganglioma, Extra-Adrenal / surgery, Retroperitoneal Neoplasms / surgery, Spinal Neoplasms / pathology, Spinal Neoplasms / therapy, Thoracic Vertebrae, Time Factors

Paragangliomas are benign neoplasms that arise from the autonomic nervous system and the associated paraganglia. Although benign, they have been shown to possess metastatic potential. Extra-adrenal retroperitoneal paraganglioma with vertebral metastasis is considered very uncommon. Here, we present a case of a functional extra-adrenal paraganglioma of the retroperitoneum giving metastasis to T4 vertebra after five years of follow-up in a 48-year-old man who had been initially treated with complete resection of the primary tumor. The condition of the patient improved significantly after radiosurgery and somatostatin analogs treatment, until lumbar spine lesions appeared six months later. Our case demonstrates that retroperitoneal paraganglioma is a rare condition which should be considered in the differential diagnosis of a retroperitoneal mass combined with vertebral lesions. Additionally, increased physician awareness and long-term follow-up is mandatory for all patients with history of retroperitoneal paraganglioma since metastases may occur after long latent intervals from the initial diagnosis.
Preliminary experience with the micro vascular plug for the treatment of pulmonary arteriovenous malformation: case series of four patients
Authors: Stevo Duvnjak, Carmela Anna Di Ciesco, Poul Erik Andersen
Journal: CVIR Endovasc (2018)
Keywords: embolisation, mvp, microplug, pavm

Background:
To describe the preliminary experience using Micro Vascular Plug (MVP) for treatment of pulmonary arteriovenous malformations (PAVMs) with small feeding arteries (3 -5 mm) in four patients with Hereditary Haemorrhagic Telangiectasia (HHT).
Material and methods:
One female and three male patients with PAVMs have been treated during 2017. The mean age was 32.5 years; (range: 20-53). All patients underwent contrast echocardiography and computed tomography of the chest to establish the diagnosis.
Results:
Four patients with PAVMs were treated with embolisation using the MVP-3Q and MVP-5Q micro plugs. All MVP were placed without complications and with following immediate occlusion of the PAVMs in all three cases. In one case MVP was placed semi selectively. All cases were with the good clinical outcomes.
Conclusion:
MVP is a new detachable embolisation material which is easy to use. Maximal control during the deployment and immediate occlusion of the target vessels can be achieved.
Complete remission after single agent blinatumomab in a patient with pre-B acute lymphoid leukemia relapsed and refractory to three prior regimens: hyperCVAD, high dose cytarabine mitoxantrone and CLAG
Authors: Katherine Linder, Deepthi Gandhiraj, Madhura Hanmantgad, Karen Seiter, Delong Liu
Journal: Exp Hematol Oncol (2016)
MeSH terms: Case Reports

Background:
The current standard of care for relapsed and refractory acute lymphoblastic leukemia (ALL) is combination chemotherapy.
Case presentation:
We report a case of highly refractory ALL who was treated with blinatumomab. The ALL in this patient relapsed within a month after completion of hyperCVAD regimen and was refractory to high dose mitoxantrone/cytarabine and CLAG regimens.
Conclusion:
This highly refractory pre-B Ph(-) ALL was induced to complete remission after one course of single agent blinatumomab.
Hypnotic Discontinuation Using a Blinded (Masked) Tapering Approach: A Case Series
Authors: Constance H Fung, Jennifer L Martin, Cathy Alessi, Joseph M Dzierzewski, Ian A Cook, Alison Moore, Austin Grinberg, Michelle Zeidler, Lara Kierlin
Journal: Front Psychiatry (2019)
Keywords: benzodiazepine discontinuation, cognitive behavioral therapy for insomnia, medication taper, nocebo effect, placebo effect

Chronic use of hypnotic medications such as benzodiazepines is associated with adverse consequences including increased risk of falls. Efforts to help patients discontinue these medications have had varying levels of success. We developed a blinded (masked) tapering protocol to help patients taper off hypnotics. In this blinded protocol, patients consented to a drug taper but agreed to forego knowledge about the specific tapering schedule or the actual dose each night until the end of the taper. Blinded tapering aims to reduce negative expectancies for withdrawal effects that may impair a patient's successful discontinuation of hypnotics. In preparation for a randomized trial, we tested the feasibility of adding a blinded tapering component to current best evidence practice [supervised hypnotic taper combined with cognitive behavioral therapy for insomnia (CBTI)] in 5 adult patients recruited from an outpatient mental health practice in Oregon. A compounding pharmacy prepared the blinded capsules for each patient. During the gradual blinded taper, each participant completed CBTI. Measures collected included feasibility/process (e.g., recruitment barriers), hypnotic use, the Dysfunctional Beliefs and Attitudes about Sleep Scale, Insomnia Severity Index, Epworth Sleepiness Scale, and Patient Health Questionnaire-9 (depressive symptoms). The intervention was feasible, and participants reported high satisfaction with the protocol and willingness to follow the same treatment again. All five participants successfully discontinued their hypnotic medication use post-treatment. Dysfunctional beliefs/attitudes about sleep and insomnia severity improved. Blinded tapering is a promising new method for improving hypnotic discontinuation among patients treated with a combination of hypnotic tapering plus CBTI.
Electromagnetic Interference from Swimming Pool Generator Current Causing Inappropriate ICD Discharges
Authors: Edward Samuel Roberto, Thein Tun Aung, Atif Hassan, Abdul Wase
Journal: Case Rep Cardiol (2017)
MeSH terms: Case Reports

Electromagnetic interference (EMI) includes any electromagnetic field signal that can be detected by device circuitry, with potentially serious consequences: incorrect sensing, pacing, device mode switching, and defibrillation. This is a unique case of extracardiac EMI by alternating current leakage from a submerged motor used to recycle chlorinated water, resulting in false rhythm detection and inappropriate ICD discharge. A 31-year-old female with arrhythmogenic right ventricular cardiomyopathy and Medtronic dual-chamber ICD placement presented after several inappropriate ICD shocks at the public swimming pool. Patient had never received prior shocks and device was appropriate at all regular follow-ups. Intracardiac electrograms revealed unique, high-frequency signals at exactly 120 msec suggestive of EMI from a strong external source of alternating current. Electrical artifact was incorrectly sensed as a ventricular arrhythmia which resulted in discharge. ICD parameters including sensing, pacing thresholds, and impedance were all normal suggesting against device malfunction. With device failure and intracardiac sources excluded, EMI was therefore strongly suspected. Avoidance of EMI source brought complete resolution with no further inappropriate shocks. After exclusion of intracardiac interference, device malfunction, and abnormal settings, extracardiac etiologies such as EMI must be thoughtfully considered and excluded. Elimination of inappropriate shocks is to "first, do no harm."
Giant right hydronephrosis with underlying double malignancy: a case report
Authors: Shreyas Nellamkuziyil Michael, Pirzada Faisal Masood, Umesh Sharma, Fibah Irshad Bhat
Journal: Pan Afr Med J (2023)
Keywords: bladder tumor, case report, giant hydronephrosis, rhabdomyosarcoma, urothelial carcinoma
MeSH terms: Carcinoma, Transitional Cell / pathology, Hydronephrosis / diagnosis, Hydronephrosis / etiology, Hydronephrosis / surgery, Rhabdomyosarcoma / pathology, Ureter / pathology, Urinary Bladder Neoplasms / complications, Urinary Bladder Neoplasms / diagnosis, Urinary Bladder Neoplasms / surgery, Case Reports, Adult, Aged, Humans, Male

Giant hydronephrosis is mostly caused by ureteropelvic junction obstruction (UPJO). Giant hydronephrosis with concurrent malignancy is less common clinically and is easily misdiagnosed. We report a 77-year-old male who presented with sudden onset progressive abdominal distension in the last month. Abdominal computed tomography showed a right severe hydronephrotic kidney with loss of parenchymal thinning. Cystoscopy showed a 1x1cm papillary lesion protruding from the right ureteric orifice. He underwent a right radical nephroureterectomy with bladder cuff excision with lymph node dissection. Histopathology showed low-grade urothelial carcinoma of the ureter and incidental pleomorphic rhabdomyosarcoma in the right kidney. The patient refused chemotherapy and died 6 months later due to lung metastasis. Incidental pathologic finding of renal rhabdomyosarcoma in adults with giant hydronephrosis and urothelial carcinoma is a rare occurrence with diverse clinical presentations, prognoses, and outcomes.
Encephalomyelitis Caused by Balamuthia mandrillaris in a Woman With Breast Cancer: A Case Report and Review of the Literature
Authors: Juan Hu, Yiqi Zhang, Yongwei Yu, Huili Yu, Siruo Guo, Ding Shi, Jianqin He, Chi Hu, Jiqi Yang, Xueling Fang, Yonghong Xiao
Journal: Front Immunol (2022)
Keywords: balamuthia mandrillaris, t-cell receptor, encephalitis, encephalomyelitis, next-generation sequencing
MeSH terms: Amebiasis / drug therapy, Amebiasis / genetics, Amebiasis / immunology, Breast Neoplasms / drug therapy, Breast Neoplasms / genetics, Breast Neoplasms / immunology, Breast Neoplasms / parasitology, Encephalomyelitis / drug therapy, Encephalomyelitis / genetics, Encephalomyelitis / immunology, Encephalomyelitis / parasitology, Case Reports, Adult, Balamuthia mandrillaris / genetics, Balamuthia mandrillaris / immunology, Fatal Outcome, Female, High-Throughput Nucleotide Sequencing, Humans, Magnetic Resonance Imaging

Balamuthia mandrillaris is one cause of a rare and severe brain infection called granulomatous amoebic encephalitis (GAE), which has a mortality rate of >90%. Diagnosis of Balamuthia GAE is difficult because symptoms are non-specific. Here, we report a case of Balamuthia amoebic encephalomyelitis (encephalitis and myelitis) in a woman with breast cancer. She sustained trauma near a garbage dump 2 years ago and subsequently developed a skin lesion with a Mycobacterium abscessus infection. She experienced dizziness, lethargy, nausea and vomiting, inability to walk, and deterioration of consciousness. Next-generation sequencing of cerebrospinal fluid (CSF) samples revealed B. mandrillaris, and MRI of both brain and spinal cord showed abnormal signals. T-cell receptor (TCR) sequencing of the CSF identified the Top1 TCR. A combination of amphotericin B, flucytosine, fluconazole, sulfamethoxazole, trimethoprim, clarithromycin, pentamidine, and miltefosine was administrated, but she deteriorated gradually and died on day 27 post-admission.
Trismus Resulting from Infantile Hemangioma of the Parotid: A Rare Case Report
Authors: E Zarepur, M Moghimi
Journal: Iran J Ped Hematol Oncol (2015)
Keywords: parotid, hemangioma, trismus, vascular abnormality
MeSH terms: Case Reports

Vascular abnormalities are characterized by increasing number of vessels. Salivary gland tumors are uncommon and their overall incidence is about 3 per 100000 per year. Salivary gland hemangioma makes up 1 % of all salivary gland tumors. Trismus resulting from parotid hemangioma is so rare. The patient was a 6-month-old boy with a huge lesion in his right parotid who referred to Shahid sadoughi hospital of Yazd, Iran. The lesion appeared at 4 months of age and had rapid growth and was suspected as hemangioma after clinical examination and patient had trismus. The lesion was excised without any complications. Five months after surgery, area of the lesion appeared normal. Parotid hemangioma has low potential to turn into malignant form but early detection and biopsy are necessary for decreasing complications. Removal of the mass was the best treatment for the patients with large or complicated hemangioma; however, it should be performed with caution because the tissues may bleed profusely. Patients may have long term survival after surgery.
Combined Immunodeficiency With Late-Onset Progressive Hypogammaglobulinemia and Normal B Cell Count in a Patient With RAG2 Deficiency
Authors: Mayra B Dorna, Pamela F A Barbosa, Andréia Rangel-Santos, Krisztian Csomos, Boglarka Ujhazi, Joseph F Dasso, Daniel Thwaites, Joan Boyes, Sinisa Savic, Jolan E Walter
Journal: Front Pediatr (2019)
Keywords: rag deficiency, rag2, combined immunodeficiency, compound heterozygous variant, hypomorphic variant, primary immunodeficiency
MeSH terms: Case Reports

Proteins expressed by recombination activating genes 1 and 2 (RAG1/2) are essential in the process of V(D)J recombination that leads to generation of the T and B cell repertoires. Clinical and immunological phenotypes of patients with RAG deficiencies correlate well to the degree of impaired RAG activity and this has been expanding to variants of combined immunodeficiency (CID) or even milder antibody deficiency syndromes. Pathogenic variants that severely impair recombinase activity of RAG1/2 determine a severe combined immunodeficiency (SCID) phenotype, whereas hypomorphic variants result in leaky (partial) SCID and other immunodeficiencies. We report a patient with novel pathogenic compound heterozygous RAG2 variants that result in a CID phenotype with two distinctive characteristics: late-onset progressive hypogammaglobulinemia and highly elevated B cell count. In addition, the patient had early onset of infections, T cell lymphopenia and expansion of lymphocytes after exposure to herpes family viruses. This case highlights the importance of considering pathogenic RAG variants among patients with preserved B cell count and CID phenotype.