OpenMed/multicare-articles huggingface dataset:
Putting things in and taking them out of containers: a young child's interaction with objects
Authors: Chihiro Nishio, Hikaru Nozawa, Hiroe Yamazaki, Kazutoshi Kudo
Journal: Front Psychol (2023)
Keywords: carrying objects, child-object interaction, development of organized behavior, natural observation, social interaction

Introduction:
How does the behavior of putting things away (putting them in) in a container and using them again (taking them out) develop in young children? Though object interaction is one of the most examined topics in child development, research on organized behavior with various objects and containers at home is lacking. Rather than conducting experiments on young children's interactions with objects, this study focused on natural child-object interaction in the home.
Methods:
We conducted a case study on a young child's natural interaction with objects at home, focusing on when the child puts them in or takes them out of a container (the shelf, the cabinet, or the box). The study took place over 2½ years.
Results:
The behaviors of putting many objects in a container and taking them out appeared at 9 months old. After acquiring the skill of walking, the child carried the objects using bags. Putting objects in and taking them out was embedded in the locomotion, and the child prepared the containers of toys before play. Pulling as many objects out as possible became rare after 19 months of age. Taking objects out became more appropriate in that context. The child brought out the container before the activity and put things away afterward.
Discussion:
Based on these findings, the development of organized object interaction as well as the anticipation and significance of the naturalistic longitudinal observations are discussed.
Surgical treatment of esophageal perforation after stereotactic body radiotherapy: A report of two cases
Authors: Takeharu Kato, Yoshihiro Kazama, Sho Matsuura, Sakae Nagaoka
Journal: Int J Surg Case Rep (2023)
Keywords: cyberknife, esophageal perforation, esophagectomy, late esophageal toxicity, stereotactic body radiation therapy, vascular endothelial growth factor inhibitor
MeSH terms: Case Reports

Introduction and importance:
Esophageal perforation due to stereotactic body radiotherapy (SBRT) is rare, and there is no consensus on the treatment strategy. Here, we report two cases of esophageal perforation caused by CyberKnife irradiation managed with distinct surgical approaches.
Case presentation:
Case 1 was a 54-year-old woman who was administered chemotherapy including bevacizumab and underwent CyberKnife SBRT for postoperative ovarian cancer (pStage IIIc) with metastasis in the eighth thoracic vertebra. Thirteen months after irradiation, she suddenly developed right back and anterior thoracic pain and was diagnosed with esophageal perforation. Despite open chest drainage and intercostal muscle (ICM) flap coverage, the fistula could not be closed, leading to pyogenic spondylitis and epidural abscess. Case 2 was of a 58-year-old woman with mediastinal lymph node metastasis 5 years after uterine cancer surgery (pStage Ia) who underwent CyberKnife SBRT. Six months after irradiation, she experienced back pain and was diagnosed with esophageal perforation. After curative esophagectomy, the patient was discharged on postoperative day 22 without any adverse effects.
Clinical discussion:
Esophageal perforation by SBRT with vascular endothelial growth factor inhibitors (VEGFI) such as bevacizumab has rarely been reported. Considering the impaired wound healing system and blood perfusion caused by radiation therapy and VEGFI, difficulty closing the perforation covered with an ICM flap was hypothesized.
Conclusion:
Late esophageal toxicity from irradiation may cause impaired blood flow and wound healing; therefore, curative esophagectomy, including at the perforation site, is effective.
Disseminated Tuberculosis Presenting as Baker's Cyst Infection
Authors: Najwa Pervin, Sami Akram, Tamer Hudali, Mukul Bhattarai, Sana Waqar
Journal: Case Rep Infect Dis (2017)
MeSH terms: Case Reports

In the absence of coexisting immunocompromised state and lack of specific symptoms a reactivation of treated mycobacterial tuberculosis (MTB) infection is generally not considered in the differential diagnosis of leg pain. We present a unique case of disseminated tuberculosis presenting as an infected Baker's cyst in a 73-year-old immunocompetent male.
Calcium pyrophosphate dihydrate crystal deposition disease of the spinal dura mater: a case report
Authors: Noriaki Wada, Koji Yamashita, Akio Hiwatashi, Osamu Togao, Ryotaro Kamei, Daichi Momosaka, Yasuhiro Maeda, Takuya Matsushita, Ryo Yamasaki, Keiichiro Iida, Yuichi Yamada, Jun-Ichi Kira, Hiroshi Honda
Journal: BJR Case Rep (2017)
MeSH terms: Case Reports

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is characterized by the accumulation of CPPD crystal in articular and periarticular tissues, but CPPD crystal deposition along the spinal dura mater has not been previously reported. We report a 54-year-old male presenting with progressive neck pain and numbness of the extremities. CT showed diffuse dorsal epidural calcification from C3-T6 which resulted in spinal canal stenosis. On MR imaging, the lesion was hypointense on both T 1 and T 2 weighted images. From these findings, CPPD crystal deposition in the ligamentum flavum was suspected preoperatively. Biopsy at the level of C5-6 were performed to confirm the diagnosis. Perioperative and histopathological findings revealed that CPPD crystals were deposited along the dorsal dura mater, not in the ligamentum flavum. We firstly report the CT and MR imaging features of a possible new concept in the differential diagnosis of CPPD crystal deposition disease.
Dieulafoy lesion in the ascending colon presenting with gastrointestinal bleeding and severe anemia complicated by a coexisting severe resistant chronic idiopathic thrombocytopenic purpura
Authors: Sherif Ali Eltawansy, Brag Thyagarajan, Nadeem Baig
Journal: Case Rep Gastrointest Med (2014)

Background. GI (gastrointestinal) bleeding can be due to a variety of etiologies ranging from being common like bleeding peptic ulcer disease or esophageal varices. One of the rarely documented causes is the Dieulafoy lesion which is known as an abnormally large ectatic artery that penetrates the gut wall, occasionally eroding through the mucosa causing massive bleeding. In addition to that, we refer to the uncommon presentation of Dieulafoy lesion itself as it is well known to be found in the stomach, esophagus, duodenum, and jejunum but not the ascending colon as in our case. The patient had a coexisting ITP (idiopathic thrombocytopenic purpura) that was resistant to different therapies. Case Report. We report a case of a 48-year-old Egyptian female known for chronic ITP resistant to treatment. The patient presented with bright red bleeding per rectum and severe life threatening anemia. Endoscopic study showed a Dieulafoy lesion. Endoscopic clipping was successful in controlling the bleeding. Conclusion. Dieulafoy lesion is a rare reason for GI bleeding and can present in common or unexpected places. Also extreme caution should be used in patients with bleeding tendency due to different reasons, like ITP in our case.
Laparoscopic Distal Pancreatectomy of a Solid Pseudopapillary Tumor (SPT) Achieves Long-Term Oncologic Safety and Multiorgan Preservation
Authors: Ahmed ElHaddad, Paolo Gasparella, Christoph Castellani, Georg Singer, Erich Sorantin, Klara Zach, Holger Till
Journal: European J Pediatr Surg Rep (2019)
Keywords: frantz tumor, laparoscopy, oncology, pancreas, solid pseudopapillary tumor
MeSH terms: Case Reports

The oncological safety of a laparoscopic approach for solid pseudopapillary tumors (SPTs) of the pancreas remains a matter of debate. We present the long-term follow-up of an adolescent girl with an SPT in the pancreatic tail. A multimodality workup including magnetic resonance imaging (MRI) revealed a complex, spherical mass of 4.4 cm × 3.6 cm × 4 cm most likely located in the pancreatic tail. All routine laboratory investigations and tumor markers were within normal limits (alpha fetoprotein [AFP], cancer antigen 125 [CA125], CA 19-9, carcinoembryonic antigen [CEA], adrenocorticotropic hormone [ACTH]). Diagnostic laparoscopy was performed to verify the origin of the tumor in the pancreatic tail. In a three-port technique the tumor was mobilized of the splenic vessels until a distal pancreatectomy could be completed. Histopathological examination confirmed the complete resection of a low-grade malignant SPT. The postoperative course was unremarkable. Regular pediatric oncological follow-up examinations for 3 years, including MRI every 6 months, ruled out recurrence and confirmed preservation of splenic and pancreatic functions. While data about the technical feasibility of a laparoscopic approach to pancreatic SPT are already available, this pediatric case report adds a long-term oncological and functional success to the available literature.
Delayed diagnosis of post-traumatic C7 vertebra anterior subluxation with an unusual neurological pattern: a case report
Authors: Maryam Sanaullah, Abdul Sattar Mohammad Hashim, Ayesha Sundus, Sanaullah Bashir, Maheen Rehman
Journal: J Med Case Rep (2013)

Introduction:
Post-traumatic subluxations are potentially devastating injuries to the axial skeleton. Of utmost priority are an expedient and timely diagnosis and realignment because of its association with spinal cord and nerve root trauma, which lead to progressive deleterious neurological deficits. A good radiological study of the occipitocervical joint and first thoracic vertebra is key to a successful early diagnosis. However, cases might still fail to be diagnosed, leading to trouble. A case of post-traumatic subluxation at the C7 vertebral level with an unusual neurological pattern is presented here.
Case presentation:
A 35-year-old farmer from the Sindh province of Pakistan presented to our neurology department after a fall 2 months earlier and complained of lower limb pain and difficulty in walking. He had numbness in both of his lower limbs up to his umbilical region, with sparing of bladder function along with intact strength in the upper extremities bilaterally.
Conclusions:
Our case highlights the unusual sparing of upper limbs and intact urinary continence with severe lower limb deficits in a 70% subluxation. Our case is unusual because highly detrimental effects such as quadriplegia are expected with such extreme subluxation, but our patient presented with only lower limb deficits. This case serves as a reminder to emergency medicine doctors, spine surgeons, and even radiologists (a) to evaluate spine injuries by using computed tomography in trauma patients to identify artifact around a suspected injury and (b) to be mindful of negative conventional radiographs.
Cutaneous pancreatic metastasis: a case report and review of literature
Authors: H Z Abdel Hafez
Journal: Indian J Dermatol (2008)
Keywords: pancreas cancer, nodules, skin metastases

Pancreatic cancer is one of the most dangerous human cancers and will continue to be a major unsolved health problem as we enter the 21(st) century. This is the case despite advances in imaging technology and surgical management. Indeed, 80% to 90% of pancreatic cancers are diagnosed either at the locally advanced or metastatic stage. Cutaneous metastases originating from pancreatic cancer are relatively rare. The most common site of cutaneous metastasis is the umbilicus, and this is known as the Sister Joseph's nodule. Very few patients have been reported with cutaneous lesions disclosing a pancreatic carcinoma at sites other than the umbilical area. To the best of our knowledge, there have been no previous reports on cutaneous pancreatic metastasis in Egypt. This is a report on a patient with cutaneous pancreatic metastases at the neck and review of reported non-umbilical cutaneous metastases from pancreatic carcinoma in the literatures.
One Environmental Health: an emerging perspective in toxicology
Authors: Adam Pérez, John Pierce Wise Sr
Journal: F1000Res (2018)
Keywords: dna repair, one health, alligator, carcinogenesis, chromium, endocrine disruptors, metals, whale
MeSH terms: Review

The One Environmental Health research approach, a subspecialty of the One Health initiative, focuses on toxic chemicals. Distinct disciplines work together to give a holistic perspective of a health concern through discrete disciplines, including, but not limited to, public health and the medical and veterinary sciences. In this article, we illustrate the concept of One Environmental Health with two case studies. One case study focuses on alligators and contributions to the field of endocrine disruption. The other case study focuses on whales and contributions to understanding carcinogenic metals. Both studies illustrate how the health of sentinel organisms has the potential to inform about the health of humans and the ecosystem.
Myocarditis and sports in the young: data from a nationwide registry on myocarditis-"MYKKE-Sport"
Authors: Isabelle Schöffl, Sophia Holler, Sven Dittrich, Thomas Pickardt, Bernd Opgen-Rhein, Martin Boehne, Bardo Wannenmacher, Katja Reineke, Gesa Wiegand, Tobias Hecht, Michael Kaestner, Daniel Messroghli, Stephan Schubert, Franziska Seidel, Annika Weigelt
Journal: Front Sports Act Living (2023)
Keywords: cardiomyopathy, heart muscle infection, prevention, return to sports, sudden cardiac death

Background:
Myocarditis represents one of the most common causes of Sudden Cardiac Death in children. Myocardial involvement during a viral infection is believed to be higher as a consequence of intensive exertion. Recommendations for return to sports are based on cohort and case studies only. This study aims to investigate the relationship between physical activity and myocarditis in the young.
Patient:
Every patient in the MYKKE registry fulfilling criteria for suspicion of myocarditis was sent a questionnaire regarding the physical activity before, during and after the onset of myocarditis.
Method:
This study is a subproject within the MYKKE registry, a multicenter registry for children and adolescents with suspected myocarditis. The observation period for this analysis was 93 months (September 2013-June 2021). Anamnestic, cardiac magnetic resonance images, echocardiography, biopsy and laboratory records from every patient were retrieved from the MYKKE registry database.
Results:
58 patients (mean age 14.6 years) were enrolled from 10 centers. Most patients participated in curricular physical activity and 36% in competitive sports before the onset of myocarditis. There was no significant difference of heart function at admission between the physically active and inactive subjects (ejection fraction of 51.8 ± 8.6% for the active group vs. 54.4 ± 7.7% for the inactive group). The recommendations regarding the return to sports varied widely and followed current guidelines in 45%. Most patients did not receive an exercise test before returning to sports.
Conclusion:
Sports before the onset of myocarditis was not associated with a more severe outcome. There is still a discrepancy between current literature and actual recommendations given by health care providers. The fact that most participants did not receive an exercise test before being cleared for sports represents a serious omission.
Small Bowel Obstruction in Postpartum Vaginal Delivery due to Prior Abdominal Adhesions Case Report
Authors: Liubin Yang, Lydia Kao
Journal: Case Rep Obstet Gynecol (2023)
MeSH terms: Case Reports

Intestinal obstruction rarely occurs after uncomplicated vaginal deliveries. Here, we present a case of a multiparous woman with a history of prior appendectomy presenting with generalized, nonspecific abdominal pain that was out of proportion to exam findings. Initial abdominal X-ray was nonspecific, and subsequent computed tomography (CT) abdomen showed closed small bowel obstruction requiring surgical repair. We present a case of intestinal obstruction occurring within 24 hours of uncomplicated vaginal delivery with a risk factor of a prior appendectomy surgery and the use of CT abdomen and pelvis to expedite diagnose.
Limy bile (Milk of calcium bile) associated with gall stones discovered incidentally during laparoscopic cholecystectomy
Authors: Sardar Hassan Arif, Ayad Ahmad Mohammed
Journal: Int J Surg Case Rep (2019)
Keywords: cholethiasis, gallstones, laparoscopic cholecystectomy, limy bile, milk of calcium bile

Introduction:
Limy bile is very rare condition in which the gall bladder is filled with a whitish material formed mainly of calcium carbonate. It may be associated with gall stones and present with epigastric and right upper quadrant pain, fever, nausea, and jaundice. The diagnosis is easily made during radiology showing opacification of the gallbladder or the bile ducts on plain abdominal X-rays and CT-scan. Most patients are treated with cholecystectomy.
Case presentation:
A 35-year-old lady was complaining from right hypochondrial pain for 8 months. The pain was mainly at the late night and relieved with analgesics. During examination the patient had no jaundice and during abdominal examination there was deep tenderness in the right hypochonrdium. Ultrasound of the gallbladder showed evidence of multiple gall stones with bile sludge. During laparoscopic cholecystectomy the gall bladder was found to be filled with white creamy substance and multiple gall stones. The patient discharged next day with no postoperative complications.
Conclusion:
Limy bile is a rare clinical entity of unknown etiology but obstruction of the cystic duct may be the most important step in its occurrence. The condition needs cholecystectomy as in most of the cases it is associated with gall stones. There are no reported long term sequelae and long term follows up is not recommended.
Gossypiboma during orthognathic surgery: A case report
Authors: Saleh Zaid Alshehri, Mohammed Ghazi Alkindi, Osama A Ibraheim, Razan A Ababtain, Randa Alfotawi
Journal: Int J Surg Case Rep (2020)
Keywords: aspiration, complications, gossypiboma, hazard, orthognathic surgery, temperature probe, unretrieved device fragment (udf)
MeSH terms: Case Reports

Introduction:
Dislodgment of nasopharyngeal temperature probes and/or unretrieved device fragments (UDFs) or gossypibome at a patient's hypopharynx is rare complication after orthognathic surgery that may occur as a result of surgical manipulation or may be a consequence of factors related to the insertion and handling of the probe after extubation. However, the exact mechanism of this complication is unknown. To the best of our knowledge, this is the 1st reported case of a missing temperature probe after orthognathic surgery.
Case presentation:
We report the case of a patient who suffered from dislodgment of a 12-cm temperature probe after orthognathic surgery. The surgery was uneventful. At the end of the surgery, the probe was believed to have been completely removed from the nasal cavity. The nasopharyngeal cavity was visually inspected while the patient was still under anaesthesia and the trachea was still intubated. Extubation was successful, and the patient was moved to the recovery area. The patient was discharged from the hospital one day after resuming an oral fluid diet. At the follow-up visit on the 4th postoperative day, the patient presented with mild symptoms of a sore throat and cough. At the follow-up visit in the 3rd postoperative week, the patient reported one episode of vomiting and severe coughing, and the patient ultimately retrieved the 12-cm temperature probe from her mouth.
Discussion:
After conducting a systematic literature review, we discuss surgical cases involving UDFs or gossypiboma. We also describe changes in our clinical practice after this event, and we envision that these modifications will have a positive influence on patient care. We believe that alternative routes for inserting temperature probes with covers would be suitable for orthognathic surgery.
Conclusion:
Vigilance should be maintained during patient extubation by both teams (surgeons and anaesthetists) to assure that part of the probe always remains visible outside the oral/nasal cavity as well as complete removal of the device to avoid this life-threating complication.
Critical appraisal of FNAC in the diagnosis of primary papillary carcinoma arising in thyroglossal cyst: A case report with review of the literature on FNAC and its diagnostic pitfalls
Authors: Kiran Agarwal, Vandana Puri, Smita Singh
Journal: J Cytol (2010)
Keywords: fnac, papillary carcinoma, thyroglossal cyst
MeSH terms: Case Reports

The incidence of primary papillary carcinoma arising in thyroglossal cyst is rare and occurs in <1% of thyroglossal cysts. Even rarer is its diagnosis by pre-operative fine needle aspiration cytology (FNAC). Only 15 such cases diagnosed by FNAC have been previously reported in the literature. In this article, cytomorphology of the current case is presented along with a review of the literature on FNAC and its diagnostic pitfalls.
Neuroleptic Malignant Syndrome (NMS) on Clozapine with a Potential Atypical Interaction with Paliperidone
Authors: Paras Agarwal, Adanegbe Omoruyi, Kiara Gascon Perai, Kerenza MacDaid, Andrea Burton
Journal: Case Rep Psychiatry (2021)
MeSH terms: Case Reports

Neuroleptic Malignant Syndrome (NMS) associated with the use of first-generation antipsychotics is a widely known phenomenon. This idiosyncratic reaction is less significant with the use of second-generation antipsychotics, and only a few cases in the literature exist, describing this reaction with clozapine use. While being titrated on clozapine, the patient developed major and minor criteria features of NMS as per the Diagnostic and Statistical Manual of Mental Disorders, Fifth edition (DSM-5) criteria except for fever, a core symptom which created diagnostic uncertainty. Initially, clozapine was temporarily discontinued due to his deteriorating mental and physical state. A rechallenge was considered at a much lower dose, but due to a rapid increase in his creatinine kinase (CK) levels within a 12-hour timeframe, clozapine was permanently stopped. The evidence further suggests that the presentation of NMS for patients on this medication may be different to the classical presentation, and other criteria for diagnosis are suggested, which may lower the threshold for investigating NMS for patients on clozapine.
Dengue and Scrub Typhus Coinfection in a Patient Presenting with Febrile Illness
Authors: Surendra Sapkota, Sudeep Bhandari, Subash Sapkota, Rabin Hamal
Journal: Case Rep Infect Dis (2017)
MeSH terms: Case Reports

Dengue fever and scrub typhus are common causes of acute febrile illness of unclear origin in Asia. Though coinfections of many vector-borne diseases have been described, articles on dengue and scrub typhus coinfection are distinctly limited. In case of coinfection with dengue and scrub typhus, vigilant monitoring of vitals, platelets transfusion, and timely treatment with doxycycline are necessary. High degree of suspicion has to be made for coinfection in a patient presenting with febrile illness with thrombocytopenia and deranged laboratory parameters in postmonsoon season in endemic regions in Asia.