OpenMed/multicare-articles huggingface dataset:
Combined open calcaneocuboid, naviculocuneiform and subtalar dislocation: A case report and literature review
Authors: Khai Phang Wong, Zhi Hao Tang, Gek Meng Tan
Journal: Biomedicine (Taipei) (2020)
Keywords: chopart joint, fracture-dislocation, lateral column, medial column, midfoot injury
MeSH terms: Case Reports

Open dislocations of the midfoot and subtalar joints are extremely rare injuries. Understanding the anatomy of these joints and the various injury patterns is imperative to obtain stable concentric reduction and provide good functional outcome. We present a report of a 26- year old male who was involved in a road traffic accident and sustained open dislocations of the calcaneocuboid, naviculocuneiform and subtalar joints. He initially underwent external fixation in view of the severe soft tissue injury. After improvement of the soft tissue condition, he underwent K-wiring of the calcaneocuboid joint, buttress plating of the talonaviculocuneiform joint, peroneal tendon reconstruction using hamstring allograft and defect coverage with a free anterolateral thigh flap. With appropriate rehabilitation protocols, patient recovered well and was allowed to weight bear as tolerated by 10 weeks. His wounds healed completely by 4 months. We report this case considering the rarity of the combined calcaneocuboid, naviculocuneiform and subtalar dislocations which were successfully managed.
Role of Unilateral Vocal Cord Palsy in Causing Recurrent Tracheobronchial Foreign Bodies
Authors: Laurence Pincet, Karma Lambercy, Kishore Sandu
Journal: Front Pediatr (2019)
Keywords: dynamic airway endoscopy, foreign body aspiration, pediatric endoscopy, recurrent aspirations, unilateral vocal cord paralysis
MeSH terms: Case Reports

Background: Foreign body (FB) aspiration in children is a frequent condition managed by ENT pediatric surgeons and pediatric pulmonologists. Methods: We present the case of a 20-months-old child who presented with three recurrent episodes of FB aspiration. Results: At the time of FB removal, an initial dynamic examination of the larynx revealed a unilateral vocal cord palsy (UVCP). Conclusion: For recurrent tracheobronchial FB inhalation, we recommend a systematic dynamic airway endoscopy.
Atypical Teratoid Rhabdoid Tumor: Two Case Reports and an Analysis of Adult Cases with Implications for Pathophysiology and Treatment
Authors: Christopher Dardis, Jared Yeo, Kelly Milton, Lynn S Ashby, Kris A Smith, Shwetal Mehta, Emad Youssef, Jenny Eschbacher, Kathy Tucker, Laughlin Dawes, Neil Lambie, Elizabeth Algar, Elizabeth Hovey
Journal: Front Neurol (2017)
Keywords: adult, etiology, pregnancy, rhabdoid tumor, statistical data analysis, statistical data interpretation, teratoma

We present the first quantitative analysis of atypical teratoid rhabdoid tumors (ATRT) in adults, including two patients from our own institutions. These are of interest as one occurred during pregnancy and one is a long-term survivor. Our review of pathological findings of 50 reported cases of adult ATRT leads us to propose a solely ectodermal origin for the tumor and that epithelial-mesenchymal transition (EMT) is a defining feature. Thus, the term ATRT may be misleading. Our review of clinical findings shows that ATRT tends to originate in mid-line structures adjacent to the CSF, leading to a high rate of leptomeningeal dissemination. Thus, we hypothesize that residual undifferentiated ectoderm in the circumventricular organs, particularly the pituitary and pineal glands, is the most common origin for these tumors. We note that if growth is not arrested soon after diagnosis, or after the first relapse/progression, death is almost universal. While typically rapidly fatal (as in our first case), long-term remission is possible (as in our second). Significant predictors of prognosis were the extent of resection and the use of chemotherapy. Glial differentiation (GFAP staining) was strongly associated with leptomeningeal metastases (chi-squared p = 0.02) and both predicted markedly worse outcomes. Clinical trials including adults are rare. ATRT is primarily a disease of infancy and radiotherapy is generally avoided in those aged less than 3 years old. Treatment options in adults differ from infants in that cranio-spinal irradiation is a viable adjunct to systemic chemotherapy in the adult population. Given the grave prognosis, this combined approach appears reasonable. As effective chemotherapy is likely to cause myelosuppression, we recommend that stem-cell rescue be available locally.
Hysterectomy and Bilateral Salpingoovariectomy in a Transsexual Subject without Visible Scaring
Authors: Anna Myriam Perrone, Maria Cristina Scifo, Valentina Martelli, Paolo Casadio, Paolo Giovanni Morselli, Giuseppe Pelusi, Maria Cristina Meriggiola
Journal: Diagn Ther Endosc (2010)
MeSH terms: Case Reports

Objective. To report on the use of laparoendoscopic single-site surgery (LESS) for the management of total hysterectomy (TH) with bilateral salpingoovariectomy (BSO) in a subject affected by gender identity disorder. Design. Case report. Setting. University Hospital. Patient(s). A 27-year-old affected by Gender Identity Disorder underwent a hysterectomy and BSO as part of surgical sex reassignment. Intervention(s). Laparoendoscopic single-site surgery access for TH and BSO. Main Outcome Measure(s). The procedure was performed without incident. The trocar placement was easy and safe, without inadvertent port removal. No vascular or visceral injuries, loss of pneumoperitoneum, or intraoperative port site bleeding occurred. Result(s). A detailed description of the technique of a single-site surgery for management of hysterectomy and BSO. Conclusion. Our case presents the first report of single-site surgery for surgical treatment of subjects affected by GID.
Ritodrine-Induced Agranulocytosis: A Case Report and Literature Review
Authors: Atsushi Daimon, Misa Nunode, Takumi Sano, Tomohito Tanaka, Daisuke Fujita, Masahide Ohmichi
Journal: Case Rep Obstet Gynecol (2020)
MeSH terms: Case Reports

Ritodrine hydrochloride is used for preterm labor, although serious side effects, including agranulocytosis, are reported. We report a case of ritodrine hydrochloride-induced agranulocytosis accompanied by bacteremia due to catheter infection. At 24 weeks of gestation, a female patient presented due to threatened premature labor and was administered continuous intravenous infusion of ritodrine hydrochloride. On day 36 after starting intravenous ritodrine hydrochloride, she was diagnosed with agranulocytosis. The white blood cell and granulocyte count nadirs were 1,660/μl and 438/μl. The cumulative dose of ritodrine hydrochloride was 2,610 mg. Ritodrine therapy was immediately stopped, and she was given an intravenous injection of antibiotics and granulocyte colony-stimulating factor. From her blood culture, methicillin-sensitive Staphylococcus aureus was detected. However, she started vaginal delivery two days after we stopped the ritodrine infusion. When using ritodrine hydrochloride, it is necessary to frequently check the white blood cell count, regardless of the total dose and treatment period.
Scalp Necrosis Revealing Severe Giant-Cell Arteritis
Authors: Safa Idoudi, Marouene Ben Kahla, Fares Mselmi, Badreddine Sriha, A Guiga, Samia Ayachi, Colandane Belajouza, Mohamed Denguezli
Journal: Case Rep Med (2020)
MeSH terms: Case Reports

Giant-cell arteritis (GCA), also referred to as temporal arteritis, is the most common primary vasculitis of the elderly involving the extracranial branches of the carotid arteries, in particular, the temporal artery. Patients usually present with temporal headaches, visual impairment, fever, and scalp tenderness. Scalp necrosis associated with GCA is a rare occurrence with approximately 100 cases reported in the literature to date. It is a therapeutic emergency requiring urgent management as it may lead to irreversible loss of vision. To increase awareness of this severe complication, we report a patient with a scalp necrosis revealing a GCA.
Retroperitoneal paraganglioma causing proximal ureteric obstruction in a child: diagnostic conundrum and immunohistochemistry characteristics (case report)
Authors: Terkaa Atim, Joshua Oluwafemi Aiyekomogbon
Journal: Pan Afr Med J (2022)
Keywords: hypertension, case report, extra-adrenal, resected, tumor
MeSH terms: Paraganglioma / diagnosis, Paraganglioma / surgery, Case Reports, Child, Humans, Immunohistochemistry, Male

Paragangliomas are extremely rare neuroendocrine tumors with an incidence of 0.3 cases per million in children. They arise from several sites in the body including the orbit, ear, nose, larynx, carotid area, mediastinum, duodenum, and the genitourinary tract. Germline mutations have been identified in paragangliomas involving the proto-oncogene RET, tumor suppressor genes VHL, and NF1 The commonest clinical presentation is hypertension but incidentally detected forms have been reported during imaging and on a few occasions the diagnosis was missed. The authors report on a case of a 12-year-old male with a history of fever, left flank pain, vomiting, and headaches, finally diagnosed by pathological examination of a resected retroperitoneal mass invading the proximal left ureter. Immunohistochemistry was positive for neuron-specific enolase, NSE (chief cells), and S-100 protein (sustentacular cells) all consistent with paragangliomas. The challenges faced by the team in the preoperative evaluation and surgical treatment are reported.
Nonfamilial Juvenile Polyposis Syndrome with Exon 5 Novel Mutation in SMAD 4 Gene
Authors: Amna Ahmed, Badr Alsaleem
Journal: Case Rep Pediatr (2017)
MeSH terms: Case Reports

Juvenile polyposis syndrome (JPS) is a rare autosomal dominant hereditary disorder, characterized by multiple juvenile polyps in the gastrointestinal tract and an increased risk of colorectal cancer. JPS is most frequently caused by mutations in the SMAD4 or BMPR1A genes. Herein, we report a child with juvenile polyposis syndrome (JPS) with a novel mutation in the SMAD4 gene. An 8-year-old boy presented with recurrent rectal bleeding and was found to have multiple polyps in the entire colon. The histology of the resected polyps was consistent with juvenile polyps. Subsequent genetic screening revealed a novel mutation in SMAD4, exon 5 (p.Ser144Stop). To the best of our knowledge, this mutation has not been reported before. Offering genotypic diagnosis for patients with JPS is an important step for strategic plan of management.
Bladder stone caused by misplaced intrauterine contraceptive device: a case report
Authors: Boniface Uji Ago, Glen Enakirerhi
Journal: Pan Afr Med J (2022)
Keywords: bladder stone, case report, intrauterine contraceptive device
MeSH terms: Foreign-Body Migration / diagnostic imaging, Foreign-Body Migration / etiology, Intrauterine Devices / adverse effects, Urinary Bladder Calculi / diagnostic imaging, Urinary Bladder Calculi / etiology, Case Reports, Female, Humans, Laparotomy / adverse effects, Ultrasonography

Intrauterine Contraceptive Device (IUCD) when placed in the uterine cavity is used for contraception or treatment of intrauterine adhesion, but it has become a cause of unintended bladder stone due to wrongful placement or migration. It may cause blood in urine and painful urination. Pelvic ultrasound and X-ray were used to make the diagnosis of the bladder stone with the embedded IUCD, which was removed by open vesicolithotomy through a Pfannenstiel suprapubic incision. Cases such as this are highly preventable if post procedure and routine annual pelvic ultrasonography are emphasized as standard practice following IUCD insertions.
Peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case report
Authors: Daiki Yamanaka, Takashi Kawano, Marie Shigematsu-Locatelli, Atsushi Nishigaki, Sonoe Kitamura, Bun Aoyama, Hiroki Tateiwa, Noriko Kitaoka, Masataka Yokoyama
Journal: JA Clin Rep (2016)
Keywords: peripheral nerve block, post-herpetic itch, tetracaine

Background:
Post-herpetic itch (PHI) is a neuropathic itch syndrome following herpes zoster. It has been reported that PHI is occasionally sufficiently severe to compromise patients' quality of life and frequently refractory to treatment. Here, we present a case of severe chronic PHI successfully treated with supraorbital nerve block using a high concentration of tetracaine dissolved in bupivacaine.
Case presentation:
An 82-year-old man presented with severe chronic itching in the ophthalmic branch of the left trigeminal nerve dermatome, following acute herpes zoster. The patient's itching was unresponsive to usual medical treatments for PHI including antiepileptic drugs, topical capsaicin cream, and supraorbital nerve radiofrequency thermo-coagulation. Topical lidocaine cream could relieve the itching, but could not provide long-term relief of itching and thus failed to achieve a satisfactory result. After these conventional treatments, left supraorbital nerve block using 4% tetracaine dissolved with 0.5% bupivacaine was conducted. Afterwards, the patient experienced long-lasting resolution of the itching with improvement of sleep disturbance. A transient, mild edema of the eyelids occurred, but there were no other complications.
Conclusions:
Peripheral nerve block using 4% tetracaine dissolved with 0.5% bupivacaine was beneficial in relieving PHI in the ophthalmic division of the trigeminal nerve.
Imaging of the spectrum of bony injuries in the diabetic foot: a case series with emphasis on non-Charcot fractures
Authors: Marcela Mautone, Parm Naidoo, Kevin Zhou
Journal: BJR Case Rep (2017)

Diabetes mellitus is associated with an increased risk of lower limb injuries. Peripheral neuropathy, often associated with diabetes, has been demonstrated to increase the risk of fracture almost two-fold and is associated with complications related to fracture healing. Detection of neuropathy-related foot injury is frequently delayed owing to the paucity of symptoms and low degree of suspicion by the clinician. Early recognition of fracture or bone injury and appropriate treatment are critical in preventing debilitating foot deformity and disability. Therefore, the astute radiologist cognizant of these potential injuries plays an essential role in early diagnosis of bony injuries in the diabetic foot. We present a series of radiological images that depict a range of osseous injuries in the diabetic foot and emphasize the role of the radiologist in early recognition of these abnormalities.
Laparoscopic treatment for an intrapancreatic accessory spleen: A case report
Authors: Yihan Zhang, Guodong Shi, Lingdong Meng, Jing Wu, Qingqiao Hu, Dong Xv, Kai Zhang, Zipeng Lu, Junlii Wu, Kuirong Jiang
Journal: Front Oncol (2022)
Keywords: imaging diagnosis, intrapancreatic accessory spleen, pancreatic neuroendocrine tumor, pathological diagnosis, surgery
MeSH terms: Case Reports

Malignant pancreatic tumors have early metastasis, aggressive behavior and poor prognosis. Surgeons often need to judge whether a patient needs prompt surgery when a pancreatic lesion is found. The accessory spleen is a congenital developmental malformation rather than a tumor and does not require surgical resection. Here, we report a 47-year-old man who underwent routine gastroscopic examination, and a submucosal eminence of the duodenal bulb was detected. The patient was asymptomatic and laboratory tests were unremarkable. Duodenal neuroendocrine neoplasm (G2) was considered following endoscopic submucosal dissection (ESD). Further examination showed a lesion in the tail of the pancreas and multiple accessory spleens. The lesion in the tail of the pancreas was Ga-68 positive and was highly considered a pancreatic neuroendocrine tumor (pNET). Based on this clinical evidence, laparoscopic spleen-preserving distal pancreatectomy (Kimura) was performed. However, the results of the postoperative pathological diagnosis indicated an intrapancreatic accessory spleen (IPAS). Given the findings of this case, we should explore more accurate diagnostic methods for IPAS to avoid unnecessary surgery.
Cronkhite-Canada syndrome: a case report and review of literature
Authors: Kevin T Kao, Jitesh K Patel, Vijayamalini Pampati
Journal: Gastroenterol Res Pract (2009)
MeSH terms: Case Reports

Cronkhite-Canada syndrome (CCS) is a rare syndrome first described in 1955. (1) Since then, 400 cases worldwide have been reported in the literature. The disease is characterized by diffuse gastrointestinal polyposis, dystrophic changes of the fingernails, alopecia, cutaneous hyperpigmentation, diarrhea, weight loss, and abdominal pain. (2) The etiology is currently unknown, but an autoimmune process is suspected. The workup is based on history and physical followed by imaging and endoscopy with biopsy to confirm gastrointestinal polyposis. The goal of treatment focuses on symptomatic management of the patient and nutritional support.
E-Cigarette- and Vaping-Related Lung Injury (EVALI) at a Regional Hospital System in South Carolina
Authors: Daniel Temas, Armin Meyer
Journal: Case Rep Pulmonol (2020)
MeSH terms: Case Reports

We report on four cases of severe lung injury and respiratory failure attributed to E-cigarette use that presented between July and August, 2019. The patients described were relatively healthy without clinically significant history of lung disease. Each developed severe acute respiratory distress shortly following E-cigarette use. In each case, the patients initially presented with considerable hypoxia and infectious-appearing pattern with elevated inflammatory markers on laboratory values. Imaging studies demonstrated a consistent pattern of widespread bilateral interstitial infiltrates with a medial distribution. All but one of the cases involved the admitted use of THC oil in E-cigarettes. There was rapid progression of illness requiring increased supplemental oxygen and in two cases, requiring urgent intubation and mechanical ventilation. No infectious organism was isolated in any case, and patients improved rapidly with the initiation of steroids. These are among the first cases reported in South Carolina and are consistent with similar cases that have been reported around the country.
Metastatic Prostate Cancer of Hand
Authors: Akihito Nagano, Takatoshi Ohno, Koji Oshima, Daichi Ishimaru, Yutaka Nishimoto, Yoshiyuki Ohno, Akihiro Hirakawa, Tatsuhiko Miyazaki, Haruhiko Akiyama
Journal: Case Rep Orthop (2016)

Soft tissue metastases of prostate cancer to other sites are extremely rare, and, to our best knowledge, there have been no reports of metastasis to soft tissue of the hand. A 63-year-old man was diagnosed with prostatic cancer. During treatment, bone and soft tissue metastases to the right hand, appearing in the first web space, were observed. The tumor was resected, along with both the first and second metacarpal bones. The thumb was reconstructed by pollicization of the remaining index finger, enabling the patient to use the pollicized thumb for activities of daily living. This is the first case report of prostate cancer metastasizing to the soft tissue in hand. After wide resection, pollicization was able to reconstruct a functional hand and thumb.
Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules
Authors: D W V N Dissanayaka, D K B Dassanayaka, P R Jayasooriya
Journal: Case Rep Dent (2020)
MeSH terms: Case Reports

Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multiple papulo-nodular lesions in the central face and a family history of a similar type of lesions from his mother. Significance of consideration of various clinical differential diagnoses with serious pathological outcomes, strategies followed in the diagnosis including histopathological evaluation aided by immunohistochemical investigations, and subsequent challenges that may be faced in the management of MFT in light of the presentation with multiple facial papules are documented in this case report.
Punctate Palmoplantar Keratoderma: A Case Report
Authors: Ariel Knowles, Maya Adams, Donald A Glass 2nd
Journal: Cureus (2023)
Keywords: aagab, inheritance, keratoderma, palmoplantar keratoderma, punctate palmoplantar keratoderma
MeSH terms: Case Reports

Palmoplantar keratoderma (PPK) is an umbrella term for a group of heterogeneous disorders, acquired or inherited, that are characterized by hyperkeratosis of palmar and/or plantar surfaces. Punctate PPK (PPPK) has been shown to have an autosomal dominant pattern of inheritance. It is linked with two loci on chromosomes 8q24.13-8q24.21 and 15q22-15q24. In type 1 PPPK, also known as Buschke-Fischer-Brauer disease, loss-of-function mutations in either the AAGAB or the COL14A1 genes have been associated with the disorder. We report here the clinical and genetic features of a patient with findings most consistent with type 1 PPPK.
The potential dangers of neck manipulation & risk for dissection and devastating stroke: An illustrative case & review of the literature
Authors: Ryan C Turner, Brandon P Lucke-Wold, Sohyun Boo, Charles L Rosen, Cara L Sedney
Journal: Biomed Res Rev (2018)
Keywords: brainstem infarct, chiropractic manipulation, medical clearance, open communication, vertebral artery dissection

Chiropractic cervical manipulation is a common practice utilized around the world. Most patients are never cleared medically for manipulation, which can be devastating for those few who are at increased risk for dissections. The high velocity thrust used in cervical manipulation can produce significant strain on carotid and vertebral vessels. Once a dissection has occurred, the risk of thrombus formation, ischemic stroke, paralysis, and even death is drastically increased. In this case report, we highlight a case of a 32-year-old woman who underwent chiropractic manipulation and had vertebral artery dissection with subsequent brainstem infarct. She quickly deteriorated and passed away shortly after arrival to the hospital. Although rare, one in 48 chiropractors have experienced such an event. We utilize this case to highlight the risk associated with cervical manipulation and urge open dialogue between chiropractors and physicians. Receiving medical clearance prior to cervical manipulation in potential at risk patients would drastically reduce morbidity and mortality.