OpenMed/multicare-articles huggingface dataset:
Analysis of cursive letters, syllables, and words handwriting in a French second-grade child with Developmental Coordination Disorder and comparison with typically developing children
Authors: Caroline Jolly, Edouard Gentaz
Journal: Front Psychol (2014)
Keywords: comparison, developmental coordination disorder, handwriting acquisition, single case study, typically developing children

Poor handwriting is a core deficit in Developmental Coordination Disorder (DCD). In a previous study, we compared the evolution of cursive letters handwriting in a girl with DCD throughout her second-grade year with that of typically developing (TD) children. We found that her handwriting evolved much less than that of TD children and remained similar to that of pre-schoolers at all stages, suggesting that her handwriting skills have reached a steady state level. We present here a continuation of this work, in which we focused on the velocity aspects of handwriting in another French child with DCD. Indeed, different velocity patterns have been observed in Chinese and English children with DCD. In the French cursive style of writing, consecutive letters are joined, a major difference with the English script style of writing. We thus analyzed the handwriting of a second-grade French girl with DCD, not only for isolated letters but also for syllables and words, in comparison to that of TD first-graders (6-7 years old; N = 85) and second-graders (7-8 years old; N = 88). Each written track was digitized, and nine kinematic parameters were measured to evaluate writing fluency. Results showed that the productions of the child with DCD were more similar to those of first-graders than to those of second-graders. In line with our previous study, the most discriminative parameters between the child with DCD and TD children were size and mean speed. Moreover, her handwriting was less fluent than that of TD children. In contrast to previous observations, we observed a higher writing velocity of the child with DCD when compared to TD children, whatever the complexity of the item, and no significant difference with TD children in the pausing time during writing. These differences may reflect linguistic specificities. For syllables and words, each letter was treated separately as a single unit, thus reflecting a problem in anticipation and automation.
Ectopic thoracic thyroid removed by uniportal VATS approach. A case report
Authors: F Carannante, L Frasca, M Depalma, F Longo, P Crucitti
Journal: Int J Surg Case Rep (2019)
Keywords: ectopic thyroid gland, minimally invasive surgery, thoracic surgery, uniportal vats

Introduction:
We speak of "Ectopic thyroid gland" when a piece of thyroid tissue is placed at a certain distance from the second to fourth tracheal cartilages.
Presentation of case:
This case report focuses on a case of a hyperplastic cystic nodule of ectopic thyroid in a 30-year-old woman treated with uniportal video-assisted thoracic surgery (VATS). The patient, was admitted to Emergency Unit for abdominal pain and vomit, underwent a CT which highlighted a mass of significant dimension on the right side of the mediastinum, in contact with close structures. The lesion has been removed with an innovative mini-invasive technique, which is characterized, differently from traditional surgical approaches, by reduced loss of blood and time of hospitalization and, in addiction to that, an aesthetic small-dimensioned scar.
Discussion:
VATS technique is minimally invasive and, moreover, it is characterized by a shorter recovery period, a minor blood loss and a shorter hospital stay. VATS has been advocated since 2010 for pulmonary resections, but today it is also performed for mediastinal intervention and a series of reports have demonstrated that it is feasible and safe.
Conclusion:
The report aims at pointing out the possibility of undergoing this kind of surgery not only in case of pulmonary mass (on which the previous literature has focused) but also when mediastinum lesions occur, as in our case.
A different surgical approach for cardiophrenic lymph node resection in advanced ovarian cancer
Authors: Lucas Minig, Miguel Arraras, Cristina Zorrero, Pedro Martinez, Manuel Patron, Juan Carlos Peñalver
Journal: Ecancermedicalscience (2017)
Keywords: advanced stage, cardiophrenic lymph node, ovarian cancer, subxiphoid approach, surgical technique
MeSH terms: Case Reports

Objective:
To describe the surgical technique of a subxiphoid approach to remove cardiophrenic lymph nodes in women with advanced ovarian cancer.
Materials and methods:
The first step is to dissect and separate the anterior insertions of the diaphragm at the xiphoid appendix. Thus, the parietal peritoneum and the upper fibres of the transversus abdominis muscle are incised. Then, the anteroinferior mediastinum is identified and dissected. Diaphragmatic deinsertion may be extended 5-7 cm laterally to the xiphoid appendix following the inferior costal margin according with the localization of the enlarged lymph nodes. Thus, the dissection of the anterolateral cardiophrenic space allows the identification of both pleura. In addition, the vertical dissection of the anterior cardiophrenic space allows the removal of enlarged lymph nodes. However, it is important to bear in mind at this time that the unintentional opening of the pleura is possible. To reduce this risk, a careful dissection of the anterior cardiophrenic fat tissue is essential. Moreover, a careful dissection will avoid damage at the left phrenic nerve as well as the left pericardiophrenic artery and vein. After removing the cardiophrenic fat tissue, the diaphragm is sutured at the lower costal margin by using separated stiches of absorbable 2-0 suture.
Conclusion:
The subxiphoid approach to resect cardiophrenic lymph nodes is a feasible surgical technique. In addition, it reduces the possibility of opening the pleural cavity, while avoiding a diaphragmatic incision, in comparison with the standard trans-diaphragmatic surgical approach.
Rare pulmonary embolism in a pregnant patient: A primary diffused pulmonary artery myxofibrosarcoma case report
Authors: Kanghui Xiang, Lu Liu, Hui-Jun Li, Guang-Wei Zhang
Journal: Front Oncol (2022)
Keywords: ecmo - extracorporeal membrane oxygenation, low-grade myxofibrosarcoma, operation, pregnancy, pulmonary embolism
MeSH terms: Case Reports

A 37-year-old female patient presented with shortness of breath, cough, and chest pain complaints from the 12th week of her first pregnancy. At the 28th week, labor induction had to be performed because of severe dyspnea and hyoxemia. Thereafter, a diffused pulmonary embolism was detected by echocardiography and CT angiography, without histological diagnosis. Pulmonary endarterectomy was performed, and it was found during operation that a huge, lobular mass originated in the posterior wall and extended throughout the vasculature of both lungs, and a mucinous pellicle covered the entire pulmonary endothelium. Pathology revealed a low-grade myxofibrosarcoma with positive vimentin and SMA, partially positive CD-34.
Amplifications of AURKA and AURKB in a Burkitt lymphoma immunodeficiency-associated type: a case report
Authors: Fábio Morato de Oliveira, Vinícius Gonçalves de Souza, Aparecida de Lourdes Carvalho, Fermino Sanches Lizarte Neto, Carla Silva Siqueira Miranda
Journal: Einstein (Sao Paulo) (2023)
MeSH terms: Burkitt Lymphoma / complications, Burkitt Lymphoma / genetics, Burkitt Lymphoma / pathology, Epstein-Barr Virus Infections, Immunologic Deficiency Syndromes, Case Reports, Adult, Aurora Kinase A / genetics, Aurora Kinase A / metabolism, Aurora Kinase B / genetics, Aurora Kinase B / metabolism, Herpesvirus 4, Human / metabolism, Humans, Male, Aurora Kinase A, Aurora Kinase B, AURKB protein, human, AURKA protein, human

In equatorial Brazil, the association of Burkitt lymphoma and Epstein-Barr virus manifests at high rates. Here, we report, for the first time, amplifications of aurora kinase genes (AURKA/B) in a patient with a history of periodontal abscess and the presence of a remaining nodule, diagnosed with Burkitt lymphoma and Epstein-Barr virus, and /HIV positive. The patient was a 38-year-old man who presented with a 2-week-old severe jaw pain and a 3-day-old severe bilateral headache. He had a history of human papilloma virus. Interphase FISH analysis showed AURKA and AURKB amplification. The patient's condition worsened, progressing to death a month after the initial care. Changes in the MYCC and AURKA pathways are directly associated with genomic instability. Thus, MYCC rearrangements and higher expression of AURKA/B may be associated with therapy resistance, highlighting the importance of AURKA/B evaluation in Burkitt lymphoma.
Trigger Twins: 2 Cases of Ipsilateral Twin Trigger Digit and a Review of Published Literature
Authors: David Brinkman, Gerard Sheridan, Michael O'Sullivan
Journal: Case Rep Orthop (2019)
MeSH terms: Case Reports

Background:
The aetiology of trigger digits has been debated since Notta first described them in 1850. Aetiology has been segregated for adult and paediatric presentations. While an adult trigger digit is most likely an acquired inflammatory process, the same is not true for cases in children: no inflammatory reaction is seen on microscopic evaluation. We wish to add strength to a genotypical aetiology for paediatric cases.
Methods:
We present two cases of monozygotic twins with trigger digits managed in our institution. A comprehensive review of literature was conducted for cases of trigger digit in monozygotic twins to support our theory.
Results:
Our two sets of twins enjoyed a full recovery from surgery at one-month follow-up. A total of seven other cases of monozygotic twins were found in literature.
Conclusion:
Our cases add to the growing body of evidence supporting a genotypical aetiology for paediatric trigger digit.
Midgut volvulus is a rare cause of intestinal obstruction in adults: A case report
Authors: Hadi Ahmadi Amoli, Ehsan Rahimpour, Negar Firoozeh, Ali Abbaszadeh-Kasbi, Seyed Ali Jazaeri
Journal: Int J Surg Case Rep (2019)
Keywords: case report, intestinal obstruction, midgut malrotation, midgut volvulus

Introduction:
The incidence of midgut vovulus is rare in adults. However, a significant number of cases were seen in infant and children.
Presentation of case:
We report a case of a 34-year-old male who presented to the emergency room with persistent periumbilical abdominal pain without any other symptoms. Contrast-enhanced CT showed clearly the typical finding of midgut volvulus like whirlpool sign, corkscrew sign, and the superior mesenteric vein to the left of superior mesenteric artery. The patient was planned for Ladd's procedure and emergency laparotomy performed successfully with an uneventful postoperative recovery.
Discussion:
Managing midgut volvulus is based on presentation. In symptomatic cases surgery is the treatment, but in asymptomatic cases, treatment is controversial.
Conclusion:
Although midgut volvulus is rare in adults, it should be considered as an intestinal obstruction.
An unusual presentation of adult T-cell leukemia/lymphoma
Authors: Mohammed Tag-Adeen, Keiichi Hashiguchi, Yuko Akazawa, Ken Ohnita, Sawayama Yasushi, Niino Daisuke, Kazuhiko Nakao
Journal: Ecancermedicalscience (2018)
Keywords: adult t-cell leukaemia/lymphoma, endoscopic findings, human t-lymphotropic virus, lymphoma, oral ulcers, oropharyngeal ulcers
MeSH terms: Case Reports

Adult T-cell Leukemia/Lymphoma (ATL) is a rare disease, related to human T-lymphotropic virus-1 (HTLV-1) and presented mainly in adulthood by generalised lymphadenopathy, hepatosplenomegaly, skin lesions and hypercalcaemia, with rare gastrointestinal and/or oral manifestations. We reported this case to raise awareness and demonstrate the therapeutic challenges of this rare disease. A 49-year-old Japanese female presented with skin papules on both forearms, painful mouth ulcers and multiple neck swellings since early February 2017. Initial clinical examination and laboratory investigations were misleading and her condition was diagnosed as candidiasis. Because of un-improvement of the case, a screening upper endoscopy was requested 2 months later and revealed characteristic oropharyngeal ulcers which were biopsied, and its pathologic examination confirmed smouldering type ATL. This case report should raise awareness of doctors and endoscopists about this disease especially in HTLV-1 endemic areas to avoid late diagnosis and help achieve earlier therapeutic decisions.
New Thrombolytic Infusion Application of Dissolving Renal Artery Embolic Thrombosis: Low-Dose Slow-Infusion Thrombolytic Therapy
Authors: Ahmet Karakurt
Journal: Case Rep Nephrol (2018)
MeSH terms: Case Reports

Renal artery thromboembolism (RATE) is an uncommon complication of renal arteries from heart chamber. Although there is no treatment protocol prescribed with guidelines, thrombolytic agents such as rt-PA are frequently used. Unfortunately, current thrombolytic agent application protocol in treatment for the RATE is used in acute myocardial infarction or acute pulmonary embolism. In this protocol, 0.9-1.0% cerebral and 4-13% noncerebral hemorrhages are seen. In contrast to this protocol, we aimed to present a case of RATE, in which we applied low-dose, slow-infusion thrombolytic therapy, and we have not observed any complication such as cerebral and noncerebral hemorrhage.
Case Report: Spontaneous Rupture of Hepatic Hemangioma
Authors: Bing Pan, Shao-Cheng Lyu, Qiang He
Journal: Front Med (Lausanne) (2022)
Keywords: emergency, hepatic hemangioma, intra-abdominal hemorrhage, spontaneous rupture, surgery
MeSH terms: Case Reports

Background:
Hepatic hemangioma (HH) is a congenital vasal malformation that seemed like the most probable benign liver neoplasm, composed of masses of blood vessels, which are anomalous in arrangement and size. In most cases, HH is asymptomatic, and patients have an excellent prognosis. According to research, the location and size of the mass are correlated with the symptoms and complications. Reports of spontaneous rupture of HH have been less reported in the literature. In this emergency condition, dynamic contrast-enhanced CT scanning, especially triple-phase computed tomography (CT) with delayed imaging, is preferred.
Case presentation:
Here, we presented two middle-aged female patients with spontaneous rupture of HH in our hospital. Following an accurate diagnosis of enhanced CT and emergency surgery, patients recovered well and were discharged from the hospital.
Conclusion:
Appropriate imaging studies, especially enhanced CT, and emergency surgery are indispensable for patients with spontaneous rupture of HH. As a surgeon, we need to pay attention to the asymptomatic patient with HH.
Jackstone: A Calculus "Toy" in the Bladder. A Case Report of Rare Entity and Comprehensive Review of the Literature
Authors: Evangelos N Symeonidis, Dimitrios Memmos, Anastasios Anastasiadis, Ioannis Mykoniatis, Eliophotos Savvides, Georgios Langas, Panagiotis Baniotis, Athanasios Bouchalakis, Stavros Tsiakaras, Panagiotis Stefanidis, Michail Stratis, Wilbert F Mutomba, Ioannis Vakalopoulos, Georgios Dimitriadis
Journal: Acta Med Litu (2022)
Keywords: benign prostate hyperplasia, bladder calculus, bladder stone disease, jackstone, prostatectomy, vesical calculus, akmenligė, gerybinė prostatos hiperplazija, prostatektomija, šlapimo pūslės akmuo, „jackstone“
MeSH terms: Case Reports

Background:
An uncommon type of urinary calculus, Jackstone was named after its distinct resemblance to the children's game "Jacks." It typically involves the bladder and, to a lesser extent, the upper urinary tract.
Case presentation:
Herein, we report a case of Jackstone vesical calculus in a 75-year-old male undergoing elective open prostate surgery for benign prostate hyperplasia refractory to medical treatment. Preoperative clinical examination revealed intermittent gross hematuria and symptoms suggestive of bladder outlet obstruction, while radiological investigation confirmed the presence of a solitary star-shaped spike-like bladder stone along with an overly enlarged prostate. Following open simple prostatectomy and concomitant intact stone removal, our patient made an uneventful postoperative recovery.
Conclusion:
This case highlights an infrequent subtype of bladder lithiasis and further expands upon the importance of promptly treating the underlying cause once this rare entity is detected. A comprehensive review of the literature on Jackstone calculi is further presented.
Dental, dermatological and radiographic findings in a case of Gorlin-Goltz Syndrome: report and review
Authors: Kumar Nilesh, Shivsagar Tewary, Sameer Zope, Jinesh Patel, Aaditee Vande
Journal: Pan Afr Med J (2017)
Keywords: nevoid basal cell carcinoma syndrome, kertocystic odontogenic tumor
MeSH terms: Basal Cell Nevus Syndrome / diagnosis, Skin Abnormalities / etiology, Stomatognathic Diseases / etiology, Case Reports, Review, Basal Cell Nevus Syndrome / physiopathology, Basal Cell Nevus Syndrome / therapy, Humans, Interdisciplinary Communication, Male, Skin Abnormalities / diagnostic imaging, Skin Neoplasms / diagnostic imaging, Skin Neoplasms / etiology, Stomatognathic Diseases / diagnostic imaging, Young Adult

Gorlin-Goltz syndrome (GGS) is a rare autosomal dominant disorder. The disease shows multiple organ involvement with variable clinical presentation. Thus a multidisciplinary approach is required for its prompt clinical diagnosis and management of this condition. This paper highlights a case of GGS presenting in a young male patient with cranial, facial, dermatological, dental and skeletal involvement. The diagnosis of the syndrome was based on its clinical presentation, radiological features and histopathological findings. A review of the diagnostic criteria is also presented.
A case report exploring activity intensity in inpatient rehabilitation after stroke
Authors: Kathryn Zalewski, Julie Kerk, Kristina Laundre, Amber Wacek, Melissa Wiedmeyer
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

Background and Purpose. Inpatient rehabilitation in countries other than the United States (US) has been described as a time where patients are often not engaged in intensive physical activity. The purpose of this case report is to explore the amount and intensity of physical activity provided in inpatient rehabilitation after stroke in the US. Methods. This study presents a case report of a person admitted to an inpatient rehabilitation unit after sustaining a first stroke. A customized data collection tracked type of activity, activity intensity and social interaction every 5 minutes during the rehabilitation day. Results. 74 percent of the day was spent in low intensity, often seated, physical activity; 14% of the day was spent resting or sleeping. Only 2.91% the day was spent in moderate or high intensity activity with a mobility focus. Conclusions. Consistent with other studies, this case report suggests a relatively low physical demand to rehabilitation delivered in inpatient stroke rehabilitation. This case begins to raise questions about optimized rehabilitation parameters for acute stroke rehabilitation.
The clinical characteristics and gene mutations associated with thyroid hormone resistance syndrome coexisting with pituitary tumors
Authors: Junyu Zhao, Lusi Xu, Chunyu Li, Fei Wang, Lin Liao, Jianjun Dong
Journal: Front Endocrinol (Lausanne) (2023)
Keywords: thrβ, clinical characteristics, gene mutation, pituitary tumors, thyroid hormone resistance syndrome
MeSH terms: Pituitary Neoplasms / complications, Pituitary Neoplasms / diagnosis, Pituitary Neoplasms / genetics, Thyroid Hormone Resistance Syndrome / complications, Thyroid Hormone Resistance Syndrome / genetics, Review, Research Support, Non-U.S. Gov't, Adolescent, Adult, Aged, Amino Acid Sequence, Child, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Mutation, Young Adult

Aims:
Resistance to thyroid hormone (RTH) and pituitary tumors are both rare diseases, and the differential diagnosis of these two diseases is difficult in some cases. There are also patients who have both conditions, making diagnosis more difficult. To better understand this aspect, we analyzed the clinical characteristics and gene mutations of RTH coexisting with pituitary tumors.
Methods:
Database retrieval was conducted in the PubMed, Cochrane Library, and SinoMed databases, and the search contents were case reports or case series of patients with RTH coexisting with pituitary tumors. The demographic, clinical manifestations, and imaging characteristics of pituitary tumors and gene mutations were summarized.
Results:
Thirteen articles involving 16 patients with RTH coexistent with pituitary tumors, consisting of 13 female patients, one male patient, and two patients with unknown sex, were included. The patients were 10 to 79 years old and most patients were 41-55 years old (43.75%). The 16 patients were from seven different countries and three continents (Asia, the Americas, and Europe). All the patients showed an abnormal secretion of TSH, and five patients underwent transsphenoidal surgery. Finally, four patients were pathologically confirmed to have TSHoma. A total of 11 different mutations occurred at nine amino acid sequence sites (251, 310, 344, 347, 383, 429, 435, 438, and 453). Two different mutations occurred in both the no. 435 and no. 453 amino acid sequences. Fourteen patients provided their treatment histories, and all had undergone different treatment regimens.
Conclusions:
Patients with both RTH and pituitary tumors had multiple clinical manifestations and different thyroid functions, imaging characteristics of pituitary tumors, genetic mutations of THRβ, and treatments. However, due to the limited number of cases, the patients were mainly women. Further studies with more cases that focus on the mechanism are still needed.
On Revelations and Revolutions: Drinking Ayahuasca Among Palestinians Under Israeli Occupation
Authors: Leor Roseman, Nadeem Karkabi
Journal: Front Psychol (2021)
Keywords: badiou’s being and event, dmt, israeli-palestinian conflict, new age, activism, prophecy, psychedelics, ritual

The ritualistic use of ayahuasca can induce a feeling of unity and harmony among group members. However, such depoliticized feelings can come in the service of a destructive political status quo in which Palestinians are marginalized. Through 31 in-depth interviews of Israelis and Palestinians who drink ayahuasca together, and through participatory observations, such rituals were examined. In this setting marginalization was structurally rooted by the group's inability to recognize Palestinian national identity or admit the ongoing Israeli injustice toward Palestinians. Although the groups avoided politics, they still find their way into these rituals. This happened through occasional ayahuasca-induced revelatory events, in which individuals were confronted with a pressing truth related to the oppressive relations between Jewish Israelis and Palestinians. Three case studies of such revelatory events are described in this paper. Affected by emotions of pain, anger, and guilt, these participants developed resistance toward the hegemonic Israeli ritual structure. This was followed by an urge to deliver an emancipatory message to the rest of the group, usually through a song. Moreover, affected subjects developed a long-lasting fidelity to the truth attained at these events. In time, this fidelity led to the expansion of ayahuasca practices to other Palestinians and the politicization of the practice. The article draws on Badiou's theory in Being and Event (1988) to analyze the relations between the Israeli ritual structure, the Palestinian revelatory event, and the emancipatory fidelity that followed. Badiou's theory elucidates the egalitarian revolutionary potential, which is part of the sociopsychopharmacology of psychedelics.