OpenMed/multicare-articles huggingface dataset:
Drug-induced subacute cutaneous lupus erythematosus secondary to Dupilumab: A case report
Authors: Miranda Waugh, Geneviève Gavigan
Journal: SAGE Open Med Case Rep (2024)
Keywords: dupilumab, drug induced, subacute cutaneous lupus erythematosus
MeSH terms: Case Reports

We present the case of a 63-year-old male with known rheumatoid arthritis, diabetes, hypertension, and peripheral neuropathy who developed drug-induced subacute cutaneous lupus erythematosus secondary to Dupilumab for his chronic hand dermatitis.
Esthetic Rehabilitation with No-Preparation Veneers Applying BOPT: A Case Report with a 12-Month Follow-Up
Authors: Dima Alawa, Mawia Karkoutly, Hussam Milly
Journal: Case Rep Dent (2024)
MeSH terms: Case Reports

A 45-year-old female patient was referred to the Department of Cosmetic Dentistry, Damascus University, seeking to improve dental aesthetics. The clinical examination showed a low smile line and microdontia in the maxillary arch. The treatment plan consisted of applying no-prep veneers with gingival modification, which is described in the biologically oriented preparation technique (BOPT) as a gingitage technique. The gingitage of the sulcus was performed using a yellow ring diamond flame with an inclination of 45 degrees, which causes it to bleed and creates a space between the internal wall of the sulcus and the axial wall of the tooth. After a 12-month follow-up, the gingiva was free of inflammation, recession, and plaque, and there was no increase in probing depth, according to the modified gingival index (MGI), gingival recession index (GRI), Silness-Loe plaque index (PI), and the community periodontal index of treatment needs (CPITN), respectively. The porcelain veneers were intact, with no chippings, cracks, and marginal discoloration. The patient was satisfied with her new smile.
Large Thrombus Entrapped in a Patent Foramen Ovale during Inferior Vena Cava Filter Protection for Venous Thromboembolism
Authors: Eiji Nakamura, Kazuyoshi Takagi, Kousuke Saku, Shinya Negoto, Tomoyuki Anegawa, Shinichi Imai, Hiroyuki Otsuka, Shinichi Hiromatsu, Eiki Tayama
Journal: Case Rep Emerg Med (2023)
MeSH terms: Case Reports

Background. A large thrombus entrapped in the patent foramen ovale (PFO) is an extremely rare condition. Moreover, it is considered even rarer after temporary inferior vena cava filter (TIVCF) placement for the prevention of fatal pulmonary embolism due to venous thromboembolism (VTE). Case Report. A 58-year-old man presented with syncope following chest pain and dyspnea due to PE exacerbation during TIVCF protection, which then led to cardiogenic shock. Echocardiography revealed a large thrombus entrapped in the PFO, and computed tomography (CT) showed a bilateral pulmonary artery embolism. The patient was treated with open surgical embolectomy for a pulmonary artery thrombus and PFO thrombus with simultaneous closure of the PFO. The patient's postoperative course was uneventful. Results and Conclusion. Surgical embolectomy was useful with respect to the feasibility of resection of both intracardiac thrombus and pulmonary artery thrombus performed simultaneously, contributing to the prevention of systemic embolisms, and echocardiography plays an important role for early diagnosis.
Moya-Moya Disease Revealed by a Non-lobar Intracerebral Hemorrhage in an Adult
Authors: Hamid Ziani Jr, Siham Nasri, Imane Kamaoui, Imane Skiker
Journal: Cureus (2024)
Keywords: ct, digital subtraction angiography, intracranial hemorrhage, moyamoya, stroke
MeSH terms: Case Reports

Moya-Moya disease (MMD) is a rare cerebral vasculopathy affecting children and adults. It is a progressive steno-occlusive arterial disease generally discovered during the etiological assessment of an ischemic or hemorrhagic stroke. Its diagnosis is based essentially on imaging. Cerebral digital subtraction angiography (DSA) remains the gold standard. We report the case of a 42-year-old male patient admitted for the loss of consciousness with a Glasgow Coma Scale (GCS) of 12/15. A brain CT scan revealed a right capsulo-lenticular hematoma with ventricular flooding and hydrocephalus. Cerebral CT angiography showed features of Moya-Moya vasculopathy, which was confirmed by a cerebral catheter angiogram.
Krukenberg tumor arising from gastric cancer presenting as Pseudo-Meigs' syndrome: a case report and literature review
Authors: Shikang Qiu, Huihui Jiang, Hanxiao Ding, Limin Feng
Journal: Front Med (Lausanne) (2024)
Keywords: krukenberg tumor, pseudo-meigs' syndrome, dyspnoea, gastric cancer, ovary
MeSH terms: Case Reports

Krukenberg tumor is a relatively uncommon metastatic ovarian cancer, typically presenting with abdominal pain and distension, primarily due to bilateral ovarian involvement. Pseudo-Meigs' syndrome, caused by a Krukenberg tumor originating from gastric cancer, is extremely rare. In this study, we report the case of a 39-year-old woman who presented with unusual manifestations of a Krukenberg tumor, where abdominal distension and dyspnea were the primary symptoms. After surgical treatment, a histopathological examination of the ovary revealed the presence of signet ring cell carcinoma. We concluded that this case coincided with Pseudo-Meigs' syndrome. Clinicians should note that Pseudo-Meigs' syndrome should be considered in patients with Krukenberg tumor, ascites, and pleural effusion, as resection of the tumor may provide long-term palliation.
A narrative case study of an older disabled Muslim woman during the COVID-19 pandemic in the UK
Authors: Amani Alnamnakani
Journal: Front Sociol (2024)
Keywords: covid-19, ageing, chronic illness, disablism, pandemic, racism, religionism, sexism

This paper explores the experiences and perceptions of Zora, an older Muslim woman living with a disability in the UK. Older disabled Muslim women in the UK often face multiple discriminations based on disability, age, gender, religious, and racial grounds and this has arguably been intensified by the COVID-19 pandemic. Drawing on multiple narrative interviews with Zora, this paper focuses on the intersections of disability, ageing, gender, race and religion within a particular social context during the COVID-19 pandemic in the UK. The paper describes the complex ways in which Zora experienced various modes of everyday disablism which were not related to the COVID-19 virus itself, rather the consequences of the movement restrictions associated with it. Much of the oppression and barriers she described were socially determined, both through direct discrimination, stares and prejudicial attitudes, and indirectly through stigmatization and an embodied fear of the reaction of others in public spaces. Nevertheless, Zora did not present herself as a victim. Instead she portrayed herself in affirmative terms, as a 'brave' woman who resisted and overcame daily social challenges and movement restrictions as part of working toward creating a more accessible, inclusive and age-friendly society. One that is inhabitable for herself and other older disabled women facing an uncertain future.
Conservative Treatment of an Unusual Presentation of Iliopsoas Phlegmon Related to Infected Intrauterine Contraceptive Device
Authors: Giuleta Jamsari, Joseph Do Woong Choi, Benedict Kakala, Hillary Hu, Gideon Sandler
Journal: Case Rep Surg (2024)
MeSH terms: Case Reports

Iliopsoas phlegmon/abscess is uncommon, and individuals often present with nonspecific symptoms. Diagnosis is often delayed and almost always requires advanced imaging techniques such as computed tomography or magnetic resonance imaging. We report a case of a 51-year-old woman who presented with right lower limb swelling and associated rash with imaging demonstrating iliopsoas abscess secondary to an infected intrauterine contraceptive device. This rare case highlights the nonspecific presentation of iliopsoas abscess and the need to consider unusual sources of infection such as an intrauterine contraceptive device in women presenting with iliopsoas phlegmon and abscess.
Ectopic parathyroid adenoma on sternocleidomastoid muscle: a case report
Authors: HuiMin Shan, ZhenPeng Jiang, Jin Xu, JingFa Li, XuSheng Zhu
Journal: Front Oncol (2024)
Keywords: spect, tc-99m-mibi, ectopic parathyroid adenoma, primary hyperparathyroidism, sternocleidomastoid muscle
MeSH terms: Case Reports

A 54-year-old woman was admitted to the hospital with a left neck mass. Enhanced CT and ultrasound examinations revealed a lesion in the left sternocleidomastoid muscle. The patient undergone right thyroid lobe resection 8 years ago. Interestingly, the lesion on the sternocleidomastoid muscle, along with the left lobe of the patient's thyroid, visually appears to form a displaced and complete thyroid in the early Tc-99m-MIBI parathyroid scintigraphy. Combined with Tc-99m-MIBI scintigraphy and abnormal PTH and blood calcium levels, the consideration was given to the lesion in the sternocleidomastoid muscle as an ectopic parathyroid adenoma. Subsequent surgical pathology confirmed this suspicion.
A comparative case study of the accommodation of students with disabilities in online and in-person degree programs
Authors: Chris Mead, Chad Price, Logan E Gin, Ariel D Anbar, James P Collins, Paul LePore, Sara E Brownell
Journal: PLoS One (2023)
MeSH terms: Disabled Persons, Students, Research Support, Non-U.S. Gov't, Humans, Universities

Fully online degree programs are an increasingly important part of the higher education ecosystem. Among the many challenges raised by the growth of fully online courses and degree programs is the question: Are institutions providing online students with disabilities accommodations that are comparable to those provided to students in traditional in-person degree programs? To explore this question, we compared students in a fully online biology degree program to students in the equivalent in-person degree program at a large research university. For each group, we assessed the frequency with which students register with the disability resource center, the range of specific accommodations provided, and course grades. Results show that students in the in-person program were nearly 30% more likely to be enrolled with the disability resource center, and that students in the online program were offered a narrower range of accommodations. However, in relative terms (i.e., compared to students without disabilities in their degree program), online students with disabilities perform better than in-person students with disabilities.
Evaluation of vascular graft infection following Bentall surgery using 18F-FDG PET/CT scan: A pediatric case report
Authors: Mehrosadat Alavi, Maryam Abdinejad, Mehdi Rezaei, Alireza Moaref
Journal: Clin Case Rep (2023)
Keywords: 18‐f‐fdg pet/ct scan, bentall surgery, vascular graft infection
MeSH terms: Case Reports

Key clinical message:
After a Bentall surgery, there is a small chance of developing a serious complication called vascular graft infection. 18F-FDG PET/CT, a new and accurate diagnostic tool, can help detect it early, especially if the symptoms are unusual.
Abstract:
A 14-year-old boy who had undergone Bentall surgery 1 year prior presented with symptoms of fever, chills, loss of appetite, and weight loss over the course of a month. The initial Bentall surgery was performed due to an aneurysm of the thoracic aorta, along with severe aortic valve insufficiency and moderate aortic valve stenosis. The patient was referred to the PET/CT department for evaluation of possible endarteritis or infection of Dacron graft, which had been reported in trans-esophageal echocardiography as suspicious findings. Despite normal blood tests, blood cultures, and other imaging modalities, the 18F-FDG PET/CT confirmed the diagnosis of vascular graft infection. This diagnostic tool allowed for timely and appropriate treatment and prevention of possible complications.
Rectal Stricture Caused by a Rare Plasmacytoid Urothelial Carcinoma
Authors: Ahmad Alnasarat, Rasheed Musa, Asaiel Makahleh, Mohammad N Kloub
Journal: Case Rep Gastrointest Med (2024)
MeSH terms: Case Reports

Malignant rectal strictures are uncommon, but they may pose a diagnostic challenge in clinical practice. We report the case of an 85-year-old male with an initially puzzling presentation of abdominal distention and discomfort. The patient was ultimately diagnosed with a rectal stricture caused by a plasmacytoid variant of urothelial cell carcinoma originating from the bladder. This case emphasizes the necessity of considering unique etiologies when evaluating rectal strictures and the aggressive character of this type of urothelial carcinoma.
Antiphospholipid antibody-related hepatic vasculitis in a juvenile after non-severe COVID-19: a case report and literature review
Authors: Qingyu Li, Jingya Li, Menglan Zhou, Ying Ge, Zhengyin Liu, Taisheng Li, Li Zhang
Journal: Front Immunol (2024)
Keywords: covid-19, antiphospholipid antibodies, non-thrombotic manifestation, pediatrics, vasculitis, vasculopathy
MeSH terms: Antibodies, Antiphospholipid / blood, Antibodies, Antiphospholipid / immunology, Antiphospholipid Syndrome / complications, Antiphospholipid Syndrome / immunology, COVID-19 / complications, COVID-19 / immunology, SARS-CoV-2 / immunology, Vasculitis / etiology, Vasculitis / immunology, Case Reports, Review, Adolescent, Female, Humans, Liver / pathology, Antibodies, Antiphospholipid

Antiphospholipid antibodies (aPL) are both laboratory evidence and causative factors for a broad spectrum of clinical manifestations of antiphospholipid syndrome (APS), with thrombotic and obstetric events being the most prevalent. Despite the aPL-triggered vasculopathy nature of APS, vasculitic-like manifestations rarely exist in APS and mainly appear associated with other concurrent connective tissue diseases like systemic lupus erythematous. Several studies have characterized pulmonary capillaritis related to pathogenic aPL, suggesting vasculitis as a potential associated non-thrombotic manifestation. Here, we describe a 15-year-old girl who develops hepatic infarction in the presence of highly positive aPL, temporally related to prior non-severe COVID-19 infection. aPL-related hepatic vasculitis, which has not been reported before, contributes to liver ischemic necrosis. Immunosuppression therapy brings about favorable outcomes. Our case together with retrieved literature provides supportive evidence for aPL-related vasculitis, extending the spectrum of vascular changes raised by pathogenic aPL. Differentiation between thrombotic and vasculitic forms of vascular lesions is essential for appropriate therapeutic decision to include additional immunosuppression therapy. We also perform a systematic review to characterize the prevalence and clinical features of new-onset APS and APS relapses after COVID-19 for the first time, indicating the pathogenicity of aPL in a subset of COVID-19 patients.
Case report: Psoriasiform eczema with immune-mediated comorbidities treated with upadacitinib
Authors: Ilaria Salvi, Aurora Parodi, Emanuele Cozzani, Martina Burlando
Journal: Front Immunol (2024)
Keywords: jak inhibitor, dermatology, psoriasiform eczema, psoriasis, eczema, upadacitinib
MeSH terms: Comorbidity, Eczema / drug therapy, Heterocyclic Compounds, 3-Ring / adverse effects, Heterocyclic Compounds, 3-Ring / therapeutic use, Psoriasis / drug therapy, Psoriasis / immunology, Case Reports, Observational Study, Adult, Alopecia Areata / drug therapy, Alopecia Areata / immunology, Colitis, Ulcerative / drug therapy, Colitis, Ulcerative / immunology, Hidradenitis Suppurativa / drug therapy, Hidradenitis Suppurativa / immunology, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Vitiligo / drug therapy, upadacitinib, Heterocyclic Compounds, 3-Ring

Immune-mediated comorbidities in patients with psoriasiform eczema are common. It can be challenging to manage multiple immune-mediated diseases, especially considering that biologic treatments are prone to causing paradoxical effects. The aim of this retrospective observational case series was to describe the course of both psoriasiform eczema and immune-mediated comorbidities in five patients treated with upadacitinib for psoriasiform dermatitis. Five patients, all male, were included. All the patients suffered from psoriasiform eczema. Moreover, two of the patients suffered from alopecia areata, two from vitiligo, one from ulcerative colitis and one from hidradenitis suppurativa. In all cases, the treatment with upadacitinib was rapidly effective on the eczema. The effectiveness on alopecia areata was good in both cases, while the results on vitiligo were only partial. The only case of ulcerative colitis achieved complete remission, while the case of hidradenitis suppurativa experience partial improvement. In conclusion, upadacitinib was effective in treating not only psoriasiform eczema, but also several immune mediated comorbidities. Additional studies are necessary to determine the efficacy of upadacitinib in alopecia areata, vitiligo and hidradenitis suppurativa.
Syncope vs. Seizure: Ictal Bradycardia and Ictal Asystole
Authors: Sumika Ouchida, Kaitlyn Parratt, Armin Nikpour, Greg Fairbrother
Journal: Case Rep Neurol Med (2024)
MeSH terms: Case Reports

Background:
Ictal arrhythmia is a rare condition that causes arrhythmic manifestations induced by epileptic seizures, including asystole or bradycardia. Ictal asystole (IA) is a very rare condition found in patients undergoing video-encephalography (EEG) monitoring. It is often related to temporal lobe epilepsy and can cause syncope, which can lead to injury or even death. Case Presentation. Two patients with epilepsy showed symptoms of syncope. Both patients underwent 4-day ambulatory EEG tests and were diagnosed with IA. Following the tests, the patients were implanted with a permanent pacemaker, and one of them underwent a temporal lobectomy. As a result of these procedures, the patients experienced a reduction in episodes of symptomatic syncope.
Conclusion:
Patients with ictal asystole and symptomatic ictal bradycardia are at increased risk of falls due to seizures. Although there are no specific guidelines for managing this condition, antiseizure medications, epilepsy surgery, and cardiac pacemaker implantation have been effective treatments.
Long axial field of view PET/CT in critically ill patients: lessons from a case report
Authors: J H van Snick, B van Leer, M W N Nijsten, J Pillay, R H J A Slart, A W J M Glaudemans, N D van Rijsewijk
Journal: Front Med (Lausanne) (2024)
Keywords: ct, fdg, icu patient, pet, critically ill, imaging procedure, nuclear medicine
MeSH terms: Case Reports

The introduction of new long axial field of view (LAFOV) scanners is a major milestone in positron emission tomography/computed tomography (PET/CT) imaging. With these new systems a revolutionary reduction in scan time can be achieved, concurrently lowering tracer dose. Therefore, PET/CT has come within reach for groups of patients in whom PET/CT previously was undesirable. In this case report we discuss the procedure of a continuous bed motion (CBM) total-body [18F]FDG PET/CT scan in an intensive care patient. We emphasize the clinical and technical possibilities with this new camera system, a matched clinical protocol, and the added value of a dedicated team.
Cyclosporine-induced alopecia:a case report, FDA adverse event reporting system analysis and literature assessment
Authors: Ying Wang, Youhong Wang, Ping Xu
Journal: Front Pharmacol (2024)
Keywords: alopecia, case report, cyclosporine, drug adverse event, immune
MeSH terms: Case Reports

Cyclosporine is a potent immunosuppressive drug for various immune-mediated diseases in children. Cyclosporine's expected therapeutic effect also carries a wide range of side effects. One of the most common and intriguing dermatological side effects is hypertrichosis. However, recent reports have recognized alopecia as a potential adverse effect of cyclosporine. Here, we report a case of a 29-month-old boy diagnosed with aplastic anemia. During cyclosporine therapy, the patient presented with hair loss on the scalp, which and subsequently spread to the eyebrows and eyelashes. The alopecic symptoms were not relieved following topical minoxidil liniment interventions. When the cyclosporine was discontinued, a remarkable improvement was observed in the scalp, with complete hair regrowth. Data concerning cyclosporine from the FDA Adverse Event Reporting System (FAERS) database were extracted from January 2004 to January 2023. Within FAERS, our post-marketing pharmacovigilance analysis detected the reporting association of cyclosporine and alopecia. In monotherapy, cyclosporine-induced alopecia was observed in 118 cases, and tacrolimus-induced alopecia signals were detected in 197 cases. Although the potential mechanism of medication-induced hair loss is unclear, we identified a potential correlation between alopecia and cyclosporine, and it is still necessary to adequately recognize and clinically monitor this paradoxical reaction.
Case report: Prostatic malakoplakia: a rare disease that has a profile mimicking prostate cancer
Authors: Yelei Ren, Weihao Chen, Mengni Zhang, Xuhui Zhang, Jiaojiao Zhou, Yongzhong Li, Diming Cai
Journal: Front Oncol (2024)
Keywords: magnetic resonance imaging, prostate-specific antigen, prostatic malakoplakia, pulmonary disease, ultrasound
MeSH terms: Case Reports

Prostatic malakoplakia (PMP) is a rare inflammatory disease, and misdiagnosis on imaging is a major reason for unnecessary punctures; however, information on imaging is even rarer. Five patients with PMP between May 2022 and February 2023 were enrolled in this study to summarize the imaging manifestations. All patients underwent ultrasound (US)-guided prostate biopsy and were confirmed by pathology, and the presence of prostate cancer was also excluded by pathology. The five patients, with a median age of 71 years (range = 58-74 years), had a median total prostate-specific antigen (T-PSA) of 10.40 ng/mL (range = 1.74-63.42 ng/mL). In two patients, chest computed tomography showed pulmonary infections. All patients underwent magnetic resonance imaging (MRI). Of these patients, four had a Prostate Imaging-Reporting and Data System (PIRADS) score of 5, while one had a score of 4. The lesions were mostly distributed in the peripheral zone of the prostate and appeared as a high signal on T1-weighted imaging (T1WI) and a low signal on T2-weighted imaging (T2WI). In the US examination, four patients had abnormal prostate morphology, with an unsmooth envelope and non-uniform parenchymal echogenicity. Four patients had increased prostate volume. US showed a hypoechoic nodule with non-uniform internal echogenicity, and an abundant internal blood flow signal was detected by color Doppler US. PSA, MRI, and US were not specific for PMP in our study, but we found that a history of co-infection may be helpful in an accurate diagnosis and to avoid unnecessary biopsy.