OpenMed/multicare-articles huggingface dataset:
Cytological diagnosis of a rare case of solid pseudopapillary neoplasm of the pancreas
Authors: Kirana Pailoor, Hema Kini, Aarthi R Rau, Yogesh Kumar
Journal: J Cytol (2010)
Keywords: solid and cystic tumor, pancreas, solid pseudopapillary neoplasm
MeSH terms: Case Reports

A 23-year-old woman presented to our hospital with nonspecific pain in the abdomen. She underwent radiological investigations, which revealed a solid and cystic mass in the tail end of the pancreas. The mass was diagnosed to be solid pseudopapillary neoplasm of the pancreas on intraoperative scrape cytology. This was further confirmed by histopathology. The cytological diagnosis enabled appropriate surgical treatment to be planned and carried out without undue delay. It is important to distinguish this rare tumor from other pancreatic tumors with similar cytohistologic features because, if diagnosed correctly and managed surgically, this neoplasm is associated with a good prognosis.
Intravitreal Ranibizumab Had Limited Effect on Cystoid Macular Edema Due to Albumin-Bound Paclitaxel: A Case Report and Literature Review
Authors: Suna Ye, Qiqi Fang, Jinyu Yao, Jianqiang Xing, Shibo Tang, Jacey Hongjie Ma
Journal: Front Oncol (2021)
Keywords: abraxane, nab-paclitaxel, albumin-bound paclitaxel, carbonic anhydrase inhibitor, cystoid macular edema, ranibizumab
MeSH terms: Case Reports

Angiographically silent cystoid macular edema (CME) is a rare complication from nab-paclitaxel. Here we report a 45-year-old woman with breast cancer who developed CME after several months of treatment with albumin-bound paclitaxel (nab-paclitaxel). Her visual acuity did not improve significantly with the cessation of nab-paclitaxel and intravitreal ranibizumab treatment. Then, brinzolamide eye drops were prescribed. One month later, her vision improved, with the macular edema significantly subsided. Finally, we reviewed other cases of CME induced by nab-paclitaxel that have been reported in the literature and discussed the underlying pathogenesis of nab-paclitaxel-induced CME.
Peroneal groove deepening as the treatment of peroneal tendon subluxation: A case report
Authors: Ihsan Oesman, Dody Kurniawan, Rio Wikanjaya
Journal: Int J Surg Case Rep (2019)
Keywords: ankle instability, peroneal groove deepening, peroneal tendon dislocation, peroneal tendon subluxation, retinaculum ligament repair

Introduction:
Peroneal tendon subluxation is a relatively rare disorder that is often misdiagnosed as an ankle sprain. It affects mainly young adults, usually during sports activities. It is mostly caused by avulsion of the superior peroneal retinaculum (SPR) from its fibular insertion, which requires surgical intervention, especially for cases of symptomatic chronic peroneal tendon subluxation and/or dislocation. We reported a case of peroneal tendon subluxation of left ankle treated with peroneal groove deepening and retinaculum ligament repair, the objective of which is to illustrate the effectiveness of this procedure.
Case presentation:
We present a case of a thirty-four-year old male with peroneal tendon subluxation of left ankle. The patient was injured while exercising two years prior to admission. He now reported pain and instability on the left ankle. We performed peroneal groove deepening and retinaculum ligament repair to treat this patient.
Discussion:
Peroneal groove deepening and retinaculum ligament repair shows an excellent clinical outcome; after the procedure, there are no major complications such as infections, wound problems or permanent discomfort. Overall, the result of surgery had been considered satisfactory. Postoperatively, the ankle was placed in a below-knee, non-weight-bearing temporary cast in semi-equinus position for two weeks.
Conclusion:
The incidence rate of peroneal tendon subluxation is relatively low, and surgery is the primary treatment of this type of injury, with various available surgical methods available for the performing surgeon. Peroneal groove deepening and retinaculum ligament repair offers a satisfactory outcome.
Lactococcus garvieae: An Uncommon Human Pathogen Causing Infective Endocarditis in a Valve-in-Valve Transcatheter Aortic Valve Replacement
Authors: Diego H González-Bravo, Sergio Alegre-Boschetti, Richard Silva-Cantillo, Joshua Mercado-Maldonado, Reyshley Ramos-Márquez, Gabriel Torres-Rivera, Carlos Cortés, Josue Mercado-Crespo
Journal: Case Rep Cardiol (2021)
MeSH terms: Case Reports

Lactococcus garvieae is a fish pathogen and an uncommon cause of human infections. There is a growing body of evidence showing its potential for causing endocarditis especially in those with prior valve surgery. In this case report, we present what we believe is the first case of endocarditis by L. garvieae affecting a valve-in-valve transcatheter aortic valve replacement that was successfully treated. Specific guidelines for the management of these patients are lacking. Our experience can contribute to the current knowledge regarding this life-threatening infection as well as to the future care of these patients. We aim to emphasize that despite not being recognized as a typical endocarditis microorganism by the Duke Criteria, the possibility of endocarditis needs to be highly entertained in patients with L. garvieae bacteremia, especially when prosthetic valves are present. Consequently, clinicians should pursue further this diagnosis with transesophageal echocardiogram and/or alternative imaging modalities (e.g., PET-CT scan and MRI) regardless of an initial negative transthoracic echocardiogram. Reaching a diagnosis of L. garvieae endocarditis led us to the decision of prolonging the antibiotic course for 6 weeks with successful results. Ultimately, surgery was not required owing to the absence of prosthetic aortic valve dysfunction and paravalvular extension of the infection.
Cost benefit analysis for green hydrogen production from treated effluent: The case study of Oman
Authors: Hind Barghash, Arwa Al Farsi, Kenneth E Okedu, Buthaina Mahfoud Al-Wahaibi
Journal: Front Bioeng Biotechnol (2022)
Keywords: cost benefit analysis, electrolysis, green hydrogen, treated effluent, wastewaters

Recently, the management of water and wastewater is gaining attention worldwide as a way of conserving the natural resources on the planet. The traditional wastewater treatment in Oman is such that the treated effluent produced is only reused for unfeasible purposes such as landscape irrigation, cooling, or disposed of in the sea. Introducing more progressive reuse applications can result in achieving a circular economy by considering treated effluent as a source of producing new products. Accordingly, wastewater treatment plants can provide feedstock for green hydrogen production processes. The involvement of the wastewater industry in the green pathway of production scores major points in achieving decarbonization. In this paper, the technical and economic feasibility of green hydrogen production in Oman was carried out using a new technique that would help explore the benefits of the treated effluent from wastewater treatment in Oman. The feasibility study was conducted using the Al Ansab sewage treatment plant in the governate of Muscat in Wilayat (region), Bousher. The results have shown that the revenue from Al Ansab STP in a conventional case is 7.02 million OMR/year, while sustainable alternatives to produce hydrogen from the Proton Exchange Membrane (PEM) electrolyzer system for two cases with capacities of 1,500 kg H2/day and 50,000 kg H2/day, would produce revenue of 8.30 million OMR/year and 49.73 million OMR/year, respectively.
Adult Wilms' Tumour: Case Report and Review of Literature
Authors: Sunny Modi, Kor Woi Tiang, Po Inglis, Stuart Collins
Journal: J Kidney Cancer VHL (2016)
Keywords: adult wilms’ tumour, nephroblastoma, renal tumour
MeSH terms: Case Reports

Wilms' tumour (nephroblastoma) is the most common renal tumour in children. Wilms' tumour in adults is extremely rare and has a poorer prognosis than paediatric Wilms' tumour. It is difficult to differentiate adult Wilms' tumour from renal cell carcinoma based on radiological findings alone. The diagnosis in adults is often serendipitous following nephrectomy for presumed renal cell carcinoma. Because of the paucity of literature, there are no standard protocols for the management of adult Wilms' tumour, and therefore, it is managed as per paediatric Wilms' tumour. Herein, we report the case of adult Wilms' tumour in a 43-year-old man, which was diagnosed unexpectedly following nephrectomy for presumed renal cell carcinoma.
A Rare Case of Soft-Tissue Infection Caused by Raoultella planticola
Authors: Karina O' Connell, Jack Kelly, Una Niriain
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

Raoultella species are Gram-negative, non-motile bacilli primarily considered to be environmental bacteria. Raoultella planticola is a rare cause of human infections. We report a case of serious soft-tissue infection in a young male tiler who presented with cellulitis of his left thumb. He had sustained a crush injury to his left thumb 10 days earlier in a soiled environment. He noted a minor break in the skin and he washed the wound out with running water. One week later, he experienced pain, erythema, and swelling of his thumb and attended his general practitioner who prescribed oral flucloxacillin and penicillin V. Despite this treatment, he noticed progressive erythema and swelling of his thumb requiring hospital admission 3 days later. He underwent washout and debridement of his thumb. Tissue obtained intraoperatively cultured Raoultella planticola. He was treated with broad-spectrum antibiotics including ciprofloxacin and made a full and rapid recovery.
Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series
Authors: Sara Radmard, Samantha E Epstein, Hannah J Roeder, Andrew J Michalak, Steven D Shapiro, Amelia Boehme, Tommy J Wilson, Juan C Duran, Jennifer M Bain, Joshua Z Willey, Kiran T Thakur
Journal: Front Neurol (2020)
Keywords: covid-19, inpatient consults, neurology, novel coronavirus, severe acute respiratory syndrome coronavirus 2

Objective: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily causes respiratory illness. However, neurological sequelae from novel coronavirus disease 2019 (COVID-19) can occur. Patients with neurological conditions may be at higher risk of developing worsening of their underlying problem. Here we document our initial experiences as neurologic consultants at a single center quaternary hospital at the epicenter of the COVID-19 pandemic. Methods: This was a retrospective case series of adult patients diagnosed with SARS-CoV-2 who required neurological evaluation in the form of a consultation or primary neurological care from March 13, 2020 to April 1, 2020. Results: Thirty-three patients (ages 17-88 years) with COVID-19 infection who required neurological or admission to a primary neurology team were included in this study. The encountered neurological problems associated with SARS-CoV-2 infection were encephalopathy (12 patients, 36.4%), seizure (9 patients, 27.2%), stroke (5 patients, 15.2%), recrudescence of prior neurological disease symptoms (4 patients, 12.1%), and neuromuscular (3 patients, 9.1%). The majority of patients who required evaluation by neurology had elevated inflammatory markers. Twenty-one (63.6%) patients were discharged from the hospital and 12 (36.4%) died from COVID-19 related complications. Conclusion: This small case series of our initial encounters with COVID-19 infection describes a range of neurological complications which are similar to presentations seen with other critical illnesses. COVID-19 infection did not change the overall management of neurological problems.
Case Report: Doubts and Pre-occupations About Being Transgender: Questioning One's Gender Identity or a Case of Obsessive-Compulsive Disorder?
Authors: Elias Aboujaoude, Vladan Starcevic
Journal: Front Psychiatry (2021)
Keywords: discrimination, gay, gender, gender dysphoria, lesbian, obsessive-compulsive disorder, sexual orientation, transgender
MeSH terms: Case Reports

We report the case of a biological female with gender identity-related doubts that were misconstrued as suggesting obsessive-compulsive disorder (OCD). The patient's parent seemed to favor an OCD explanation for the gender-based self-questioning over acceptance of possible transgender identity. We discuss what OCD is and what it is not in the context of gender identity-based doubt; analogy with the better studied sexual orientation-related OCD; cultural flashpoints around sex and gender that can become the object of OCD; how confusion about biological sex, assigned gender and gender identity can lead to clinical harm; and the role of mental health professionals in fighting the stigma faced by gender minorities.
Response of Leptomeningeal Metastases in EGFR-Mutated Non-Small-Cell Lung Cancer to Afatinib in the Absence of Radiotherapy
Authors: Néstor Llinás-Quintero, David González-Hoyos, Andrés Yepes, Diego A Herrera, Sebastián Peláez-Arroyave, Carlos Caicedo-Zamudio, Erick Blanco-Daza, Javier Cuello-López
Journal: Case Rep Oncol Med (2019)
MeSH terms: Case Reports

Palliative radiotherapy is currently the medical standard of care for non-small-cell lung cancer (NSCLC) patients with symptomatic CNS and leptomeningeal disease. We report the case of a 62-year-old male patient with EGFR mutation (del19+) NSLC with symptomatic lymph node, bone, CNS, and leptomeningeal metastases. Taking into account on one hand the response to tyrosine kinase inhibitors (TKIs) and on the other hand the short- to medium-term side effects of radiotherapy and the lack of timely availability in our healthcare system, the patient was treated with afatinib (40 mg daily) and exhibited a rapid response with improvement of neurological symptoms. The patient presented partial response of extracranial, CNS, and leptomeningeal lesions at 3, 6, and 12 months of treatment, currently completing 16 months of progression-free survival despite presenting mild dermatological and gastrointestinal toxicities. Afatinib is an effective and safe option in patients with NSLC EGFR mutation del19+ with CNS and leptomeningeal compromise avoiding or delaying radiotherapy and its side effects, especially in countries where there is a lack of access to this kind of therapy.
Giant appendiceal leiomyosarcoma: a rare and unusual tumour
Authors: Christine Natalia, Cherry E Koh, Peter J Lee
Journal: Case Rep Surg (2011)
MeSH terms: Case Reports

Appendiceal tumours are uncommon but may be present in 0.9-1.4% of all appendicectomy specimens. While carcinoid tumours and adenocarcinomas comprise the majority of appendiceal tumours, rarely, lymphomas or sarcomas may also present in the appendix. Appendiceal leiomyosarcomas are rare, and to date, only a handful of cases have been reported. The current paper presents a case of giant appendiceal leiomyosarcoma followed by a review of the literature.
Arteriovenous malformation in temporal lobe presenting as contralateral ocular symptoms mimicking carotid-cavernous fistula
Authors: Fadzillah Mohd-Tahir, Ishak Siti-Raihan, W H Wan Hazabbah
Journal: Case Rep Ophthalmol Med (2013)

Aim. To report a rare case of arteriovenous malformation in temporal lobe presenting as contralateral orbital symptoms mimicking carotid-cavernous fistula. Method. Interventional case report. Results. A 31-year-old Malay gentleman presented with 2-month history of painful progressive exophthalmos of his left eye associated with recurrent headache, diplopia, and reduced vision. Ocular examination revealed congestive nonpulsating 7 mm exophthalmos of the left eye with no restriction of movements in all direction. There was diplopia in left lateral gaze. Left IOP was elevated at 29 mmHg. Left eye retinal vessels were slightly dilated and tortuous. CT scan was performed and showed right temporal arteriovenous malformation with a nidus of 3.8 cm × 2.5 cm with right middle cerebral artery as feeding artery. There was dilated left superior ophthalmic vein of 0.9 mm in diameter with enlarged left cavernous sinus. MRA and carotid angiogram confirmed right temporal arteriovenous malformation with no carotid-cavernous fistula. Most of the intracranial drainage was via left cavernous sinus. His signs and symptoms dramatically improved following successful embolisation, completely resolved after one year. Conclusion. Intracranial arteriovenous malformation is rarely presented with primary ocular presentation. Early intervention would salvage the eyes and prevent patients from more disaster morbidity or fatality commonly due to intracranial haemorrhage.
Case Report: Adult degenerative scoliosis in two patients treated with percutaneous spinal endoscopic-assisted lumbar interbody fusion and percutaneous pedicle screw fixation
Authors: Jian-Wei Du, Lei-Ming Zhang, Yu-Qiu Yan, Ya-Ning Zhang, Xue-Qin Rong, Song-Hua Xiao, Xi-Feng Zhang
Journal: Front Surg (2023)
Keywords: cobb angles 3, adult degenerative scoliosis, endoscopy, minimally invasive surgery, orthopedics
MeSH terms: Case Reports

Adult degenerative scoliosis (ADS) is a serious disease that often affects middle-aged and elderly people. ADS does not only cause sagittal and coronal deformity of the lumbar spine but also causes severe back and leg pain secondary to the compression of the neural structures. Open surgery remains the main method for correcting the occurring deformity and decompression of the neural structures; however, its benefit is limited in cases of large trauma. Minimally invasive spinal (MIS) surgery is an alternative method that has recently witnessed rapid development. It has the advantage of providing rapid recovery with less trauma as compared to conventional open surgery. We report two cases of ADS treated with percutaneous spinal endoscopic-assisted lumbar interbody fusion (EALIF) and percutaneous pedicle screw fixation. Both cases had moderate deformities of the lumbar spine (load-sharing classification 4-7 points) with severe back and leg pain, and they underwent successful MIS surgery. At 6 months of follow-up, the visual analog scale and Oswestry disability index scores of both patients improved and the deformity was corrected. For moderate ADS, percutaneous spinal EALIF and percutaneous pedicle screw fixation may achieve an effective correction of the deformity with direct decompression of neural structures.
Clinical Results of Total Hip Arthroplasty in Two Patients with Charcot Hip Joints due to Congenital Insensivity to Pain with Anhydrosis
Authors: Daisuke Inoue, Tamon Kabata, Yoshitomo Kajino, Tadashi Taga, Takashi Yamamoto, Tomoharu Takagi, Takaaki Ohmori, Hiroyuki Tsuchiya
Journal: Case Rep Orthop (2018)
MeSH terms: Case Reports

Traditionally, Charcot arthropathy has been considered an absolute contraindication for total hip arthroplasty (THA). However, some recent reports have shown that good short- to mid-term results can be achieved by improving the durability of the implant. This paper reports the mid- to long-term results of THA in two patients with Charcot hip joints caused by congenital insensivity to pain with anhydrosis. Both patients suffered multiple posterior dislocations in the six months immediately following surgery. However, with the continuous use of a hard abduction brace, one patient was eventually able to walk with a lofstrand cane and the other with the use of one crutch. Although one patient experienced a dislocation five years after surgery, X-rays taken after nine years and five years, respectively, revealed no clinical signs of implant loosening. We conclude that, with careful planning and appropriate precautions, THA may be a viable treatment option for Charcot hip joints caused by congenital insensivity to pain with anhydrosis.
Myoclonic Epilepsy: Case Report of a Mild Phenotype in a Pediatric Patient Expanding Clinical Spectrum of KCNA2 Pathogenic Variants
Authors: Lorenzo Perilli, Gioia Mastromoro, Manuel Murciano, Ilaria Amedeo, Federica Avenoso, Antonio Pizzuti, Cristiana Alessia Guido, Alberto Spalice
Journal: Front Neurol (2022)
Keywords: kcna2, classification, drug therapy, epilepsy, epilepsy—abnormalities, epileptic encephalopathies, genetic variants, genotype-first approach
MeSH terms: Case Reports

We report on the rare case of a male toddler presenting with myoclonic epilepsy characterized by daily episodes of upward movements of the eyebrows, and myoclonic jerks of both head and upper limbs. In addition, the child showed speech delay, tremors, and lack of motor coordination. Next Generation Sequencing analysis (NGS) performed in trio revealed in the proband the c.889C>T de novo missense variant in the KCNA2 gene in heterozygous state. This is the first case of myoclonic epilepsy in a toddler due to a c.889C>T KCNA2 missense variant. The patient was treated with valproic acid and ethosuximide with a good clinical response. At 6 years old, follow-up revealed that the proband was seizure-free with tremors and clumsiness in movements. According to the literature, this case supports the correlation between myoclonic epilepsy and KCNA2 alterations. This evidence suggests that performing genomic testing including the KCNA2 gene in preschool patients affected by myoclonic epilepsy, especially when associated with delayed neurodevelopment. Our goal is to expand the phenotypical spectrum of this rare condition and adding clinical features following a genotype-first approach.
Pleomorphic adenoma: a rare presentation in buccal salivary gland with extensive squamous and mucous metaplasia
Authors: Aadithya Basavaraj Urs, Jeyaseelan Augustine, Deepika Negi, Rudra Deo Kumar, Sujoy Ghosh
Journal: Pan Afr Med J (2019)
Keywords: buccal mucosa, mucous metaplasia, pleomorphic adenoma, squamous metaplasia
MeSH terms: Adenoma, Pleomorphic / diagnosis, Mouth Mucosa / pathology, Salivary Gland Neoplasms / diagnosis, Salivary Glands, Minor / pathology, Case Reports, Adenoma, Pleomorphic / pathology, Adult, Humans, Male, Metaplasia, Salivary Gland Neoplasms / pathology

Pleomorphic Adenoma (PA) is the most common salivary gland tumor and accounts for about 60% of all salivary gland neoplasms. Intraorally, the hard palate is the most common presenting site (50-60%) followed by upper lip (15-20%) and rarely buccal mucosa (8-10%). Histopathologically, PA shows diverse morphology resulting from amalgamation of cellular and stromal components. The PA may show changes in the stromal and epithelial components, such as sebaceous, lipocytic and oncocytic metaplasia. A rare characteristic of PA is to show extensive squamous and mucous differentiation which poses diagnostic dilemma to the pathologist. Here, we present an unusual case of PA of buccal minor salivary gland with squamous and mucous metaplasia. The localization, gender and microscopic features of the presented case are unusual.