OpenMed/multicare-articles huggingface dataset:
t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature
Authors: Katherine A Minson, Pinki Prasad, Susan Vear, Scott Borinstein, Richard Ho, Jennifer Domm, Haydar Frangoul
Journal: Case Rep Hematol (2013)

Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. There are several case reports in the literature describing t(17;19) in children with ALL. This translocation has been associated with hypercalcemia, coagulopathy, and poor outcome. We present three cases of ALL with t(17;19) treated at our institution and review the outcome of children reported in the medical literature.
Parallel Mapping and Catheter Ablation of Polymorphic Premature Ventricular Contractions: A New Feature for Activation Mapping
Authors: Moritz Nies, Ruben Schleberger, Leon Dinshaw, Andreas Rillig, Andreas Metzner, Christian Meyer
Journal: Case Rep Cardiol (2021)
MeSH terms: Case Reports

We report the case of an 80-year-old female presenting with polymorphic premature ventricular contractions, nonischemic cardiomyopathy, and severe, secondary mitral regurgitation. Despite a low intraprocedural PVC burden, activation mapping and successful ablation of different morphologies were achieved using a novel mapping tool, which facilitates simultaneous mapping of different PVC morphologies.
Herpetic Stromal Keratitis following Selective Laser Trabeculoplasty
Authors: Nisha Chadha, David A Belyea, Sanjeev Grewal
Journal: Case Rep Ophthalmol Med (2016)

This is a case report describing two cases of disciform corneal edema following uncomplicated selective laser trabeculoplasty (SLT) thought to be secondary to herpes simplex virus (HSV) given the presence of a dendrite, decreased corneal sensation, corneal thinning, and response to therapy with oral and topical antivirals. Corneal edema after SLT treatment has been reported before, but the etiology has been unclear. Our cases highlight HSV as a likely etiology, which may help with prevention and better management of such cases in the future.
A Case of Babesiosis in a Pregnant Patient Treated with Red Blood Cell Exchange Transfusion
Authors: Baruch Abittan, Aaron Nizam, Michael Oey, Felicia Callan, Lisa Simmonds, Sarah L Pachtman
Journal: Case Rep Obstet Gynecol (2019)
MeSH terms: Case Reports

Babesiosis, caused predominantly by Babesia microti, is an emerging health risk in the Northeastern and Midwestern United States. We present a case of a pregnant woman with history of splenectomy diagnosed with babesiosis at 23 5/7 weeks of gestational age refractory to antimicrobial therapy. She underwent the first reported red blood cell exchange transfusion for babesiosis in pregnancy, at 24 4/7 weeks of gestational age, which resulted in resolution of parasitemia. She had a full term, uncomplicated cesarean delivery. Exchange transfusion is potentially a safe treatment option for severe babesiosis infection in pregnancy and should be considered when other methods are poorly tolerated or ineffective.
Pneumocephalus Following Self-Inflicted Penetrating Brain Injury
Authors: Che-Fang Ho, Yuan-Yun Tam, Chia-Chen Wu
Journal: Case Rep Otolaryngol (2017)
MeSH terms: Case Reports

Objective:
Pneumocephalus is a rare complication that often occurs after traumatic skull base injury, leading to morbidity and mortality.
Material and method:
We present the case of a 42-year-old healthy man who injured himself when he stuck a metal stick into his left nasal cavity to relieve prolonged nasal obstruction. Immediate cerebrospinal fluid rhinorrhea and subsequent meningitis and pneumocephalus occurred later. He was presented at our hospital with fever and meningeal signs.
Result:
Computed tomography scans revealed left rhinosinusitis and air collection in the subarachnoid space. The patient received the conservative treatment of bed rest, intravenous hydration, head elevation, and broad-spectrum intravenous antibiotics. Pneumocephalus and meningitis resolved without any surgery, and he experienced no other sequela or complication.
Conclusion:
Pneumocephalus is a rare incidence and can lead to high morbidity and mortality. Prompt diagnosis and adequate treatment of pneumocephalus and meningitis proved beneficial for our patient who recovered without any complication or surgery.
Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange
Authors: Christelle El Khoury, Toni Sabbouh, Hussein Farhat, Antoine Ferzli
Journal: Case Rep Med (2017)
MeSH terms: Case Reports

We report a case of a bodybuilder who took a regimen of anabolic steroids containing stanozolol and testosterone propionate for 8 weeks which led to the development of jaundice and severe pruritus with serum total bilirubin reaching 41.22 mg/dL. Despite supportive care with fluid and albumin therapy, serum creatinine was progressively increasing. He underwent 6 successful sessions of plasma exchange (PE) with marked improvement at the end of the sessions. Three months after discharge, the patient's creatinine and total bilirubin levels were 1.08 mg/dL and 1.2 mg/dL, respectively.
Radix entomolaris in mandibular first molars in Indian population: a review and case reports
Authors: Kanika Attam, Ruchika Roongta Nawal, Shivani Utneja, Sangeeta Talwar
Journal: Case Rep Dent (2012)

Purpose. The aim of this paper is to present cases of mandibular first molars with an additional distolingual root and their management using appropriate instruments and techniques. Basic Procedures and Main Findings. Mandibular molars can sometimes present a variation called radix entomolaris, wherein the tooth has an extra root attached to its lingual aspect. This additional root may complicate the endodontic management of the tooth if it is misdiagnosed or maltreated. This paper reviews the prevalence of such cases in Indian population and reports the management of 6 such teeth. Principal Conclusions. (1) It is crucial to be familiar with variations in tooth/canal anatomy and characteristic features since such knowledge can aid location and negotiation of canals, as well as their subsequent management. (2) Accurate diagnosis and careful application of clinical endodontic skill can favorably alter the prognosis of mandibular molars with this root morphology.
Spontaneous Retroperitoneal Hemorrhage in a Patient with Acquired Cystic Kidney Disease
Authors: Ahmed Kotb, Asmaa Ismail, Hazem Elmansy, Owen Prowse, Walid Shahrour
Journal: J Kidney Cancer VHL (2020)
Keywords: hemodialysis, lumbotomy, retroperitoneal hemorrhage
MeSH terms: Case Reports

Spontaneous retroperitoneal hemorrhage (SRH) is a rare emergency. It is usually encountered in patients on hemodialysis and is associated with high rate of morbidity and mortality. This is a case from the emergency department. The patient had unstable vitals with SRH following dialysis. Immediate exploration and nephrectomy using transverse lateral lumbotomy incision were done. Patients on hemodialysis are at a risk of SRH and frequent surveillance is recommended. Acquired cystic kidney disease (ACKD) can develop in hemodialysis patients and put them at risk for bleeding. Transverse lateral lumbotomy may be a safe option for direct access to the kidney in emergency kidney surgery.
Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole: report of a case
Authors: Myriam Rachad, Hikmat Chaara, Fatim Zahra Fdili, Hakima Bouguern, Abdilah Melhouf
Journal: Pan Afr Med J (2011)
Keywords: ovaries, hyperstimulation syndrome, invasive mole, spontaneous pregnancy
MeSH terms: Hydatidiform Mole, Invasive / complications, Ovarian Hyperstimulation Syndrome / etiology, Uterine Neoplasms / complications, Case Reports, Adult, Antineoplastic Combined Chemotherapy Protocols / therapeutic use, Ascites / etiology, Ascites / surgery, Biomarkers, Tumor, Chorionic Gonadotropin, beta Subunit, Human / blood, Combined Modality Therapy, Cyclophosphamide / administration & dosage, Dyspnea / etiology, Electrocoagulation, Etoposide / administration & dosage, Female, Humans, Hydatidiform Mole, Invasive / blood, Hydatidiform Mole, Invasive / diagnostic imaging, Hydatidiform Mole, Invasive / drug therapy, Hydatidiform Mole, Invasive / surgery, Hysterectomy, Methotrexate / administration & dosage, Ovarian Hyperstimulation Syndrome / blood, Paracentesis, Parity, Polycystic Ovary Syndrome / complications, Polycystic Ovary Syndrome / diagnostic imaging, Polycystic Ovary Syndrome / surgery, Pregnancy, Radiography, Ultrasonography, Uterine Neoplasms / blood, Uterine Neoplasms / diagnostic imaging, Uterine Neoplasms / drug therapy, Uterine Neoplasms / surgery, Biomarkers, Tumor, Chorionic Gonadotropin, beta Subunit, Human, Etoposide, Cyclophosphamide, Methotrexate

It is known that most cases of Ovarian Hyperstimulation Syndrome (OHSS) are associated with the therapies for ovulation induction. However, OHSS may rarely be associated with a spontaneous ovulatory cycle, usually in the case of multiple gestations, hypothyroidism or polycystic ovary syndrome. We report a case of severe OHSS in spontaneous pregnancy with invasive mole in a 34 years old woman. The clinical picture showed abdominal pain, massive ascites, nausea, dyspnea and amenorrhea. After imaging examinations and laboratory tests, the diagnosis was established. The patient was managed expectantly with no complications. Although spontaneous ovarian hyperstimulation is a rare entity, it is important that the physician recognizes this condition. Prompt diagnosis and successful management is likely to avoid serious complications, which may develop rapidly.
COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome
Authors: Rafat Mosalli, Amirah Al Matrafi, Mohammed A Ghazi, Gamal A Aboumousatafa, Bosco Paes
Journal: Case Rep Pediatr (2021)
MeSH terms: Case Reports

The coronavirus disease-2019 (COVID-19) is usually less severe and less prevalent in the pediatric population. Children with preexisting conditions such as neuromuscular impairments and chronic lung disease are more susceptible to COVID-19 and may incur several complications with a poor outcome. We present a case report of a 3-year-old-female with generalized hypotonia and respiratory failure due to spinal muscular atrophy who tested positive for COVID-19 and developed multisystem inflammatory syndrome that was treated with intravenous immunoglobulin and tocilizumab and subsequently died. The report highlights the importance of close surveillance, the use of protective measures during hospital visits, early testing, and diagnosis of COVID-19 in children with neurological disorders.
Retained Needle in the AirSeal Trocar During Robot-Assisted Laparoscopic Radical Prostatectomy: Lessons Learned
Authors: Matthew Moynihan, Alireza Moinzadeh
Journal: J Endourol Case Rep (2018)
Keywords: airseal, needle, prostatectomy, robotic, trocar
MeSH terms: Case Reports

Background: Unique case of retained needle in the AirSeal trocar during robot-assisted laparoscopic radical prostatectomy. Case Presentation: A 68-year-old male with prostate cancer underwent robot-assisted laparoscopic radical prostatectomy. Upon laparoscopic removal of final intra-abdominal suture by bedside assistant, needle became dislodged from suture and was unable to be located after a standard systematic search. Ultimately, needle was found caught in the assistant's AirSeal trocar device. Conclusion: Intraoperative loss of a foreign body should include inspection, and possible radiographic evaluation, of the trocar mechanism as part of a complete systematic approach.
Carotid Bifurcation With Tandem Stenosis-A Patient-Specific Case Study Combined in vivo Imaging, in vitro Histology and in silico Simulation
Authors: Jiaqiu Wang, Phani Kumari Paritala, Jessica Benitez Mendieta, Yuantong Gu, Owen Christopher Raffel, Tim McGahan, Thomas Lloyd, Zhiyong Li
Journal: Front Bioeng Biotechnol (2019)
Keywords: atherosclerosis, carotid bifurcation, computational fluid dynamics (cfd), histology, tandem stenosis

A patient-specific carotid bifurcation with tandem stenosis found at both internal carotid artery (ICA) and common carotid artery (CCA) was studied. The in vivo pre-carotid endarterectomy (pre-CEA) multi-spectral magnetic resonance imaging (MRI) were performed and in vitro post-CEA carotid plaque tissue sample was collected. MR imaging data and tissue sample staining histology were used to recognize the plaque components. Further, the computational fluid dynamics (CFD) were performed on four MR-based reconstructed 3D carotid bifurcation models (the patient-specific geometry with tandem stenosis and three presumptive geometries by removing the stenosis part). The flow and shear stress behavior affected by the tandem stenosis was analyzed. From the results of MR segmentation and histology analysis, plaque lipid pool and calcification were found at both ICA and CCA. From the result of CFD simulation, the flow shear stress behavior suggested the tandem stenosis as a more "dangerous" situation than a single-stenosis artery. Besides, the CFD results deduced that the stenosis at the CCA location formed initially and led to the subsequent formation of stenosis at ICA. This study suggests that when planning CEA, CFD simulation on the presumptive models could help clinicians to estimate the blood flow behavior after surgery. Particular attention should be paid to the case of tandem stenosis, as the local hemodynamic environment is more complex and treatment of one stenosis may lead to a variation in the hemodynamic loading on the second plaque, which may result in either a higher risk of plaque rupture or restenosis.
A Rare Case of Contralateral Diaphragm Paralysis following Birth Injury with Brachial Plexus Palsy: A Case Report and Review of the Literature
Authors: Audra J Reiter, Yazan K Rizeq, Benjamin T Many, Jonathan C Vacek, Fizan Abdullah, Seth D Goldstein
Journal: Case Rep Pediatr (2020)
MeSH terms: Case Reports

Clinical History. A 4.4 kg male was born to a 25-year-old, G2P1, nondiabetic woman at 39 and 5/7 weeks. Delivery was complicated by shoulder dystocia requiring forceps-assisted vaginal delivery, resulting in left arm Erb's palsy secondary to left brachial plexus injury. He was born with low muscle tone and bradycardia and subsequently required intubation for poor respiratory effort. He was extubated on day one of life but continued to be tachypneic and have borderline oxygen saturation, requiring intensive care. Chest radiographs demonstrated a progressive clearing of his lung fields, consistent with presumptively diagnosed meconium aspiration. However, a persistent elevation of the right hemidiaphragm was noted, and his tachypnea and increased work of breathing continued. Focused ultrasound of the diaphragm was performed, confirming decreased motion of the right hemidiaphragm. Following a multidisciplinary discussion, thoracoscopic right diaphragm plication was performed on the 33rd day of life. He was extubated postoperatively and subsequently weaned to room air with a notable decrease in tachypnea over 48 hours. He was discharged on postoperative day 12 and continues to thrive at 6 months of age without respiratory embarrassment. Purpose. Ipsilateral phrenic nerve injury with diaphragm paralysis from shoulder dystocia during vaginal delivery is a recognized phenomenon. Herein, we present a case of contralateral diaphragm paralysis in order to draw attention to the clinician that this discordance is possible. Key Points. According to Raimbault et al., clinical management of newborns who experience birth injury is a multidisciplinary effort. According to Fitting and Grassino, though most cases of phrenic nerve injuries are ipsilateral to shoulder dystocia brachial plexus palsy, contralateral occurrence is possible and should be considered. According to Waters, diaphragm plication is a safe and effective operation.
Late diagnosis of celiac disease in an asymptomatic infant with growth failure
Authors: Mauro Bozzola, Elena Bozzola, Sara Pagani, Amelia Mascolo, Rossella Porto, Cristina Meazza
Journal: Ital J Pediatr (2014)
MeSH terms: Body Composition, Celiac Disease / diagnosis, Delayed Diagnosis, Failure to Thrive / complications, Case Reports, Biopsy, Celiac Disease / complications, Celiac Disease / genetics, Child, Preschool, Diagnosis, Differential, Female, Follow-Up Studies, HLA-DQ Antigens / genetics, Haplotypes, Humans, Intestinal Mucosa / pathology, Time Factors, HLA-DQ Antigens, HLA-DQ2 antigen

The clinical spectrum for celiac disease (CD) is broad and includes cases with either typical (intestinal) or atypical (extraintestinal) features, often making the diagnosis of CD very difficult.We describe the case of a girl presenting with stunted growth and malnourishment. She was evaluated at 14 months for decreased growth rate without any signs of gastrointestinal, renal or endocrine disorders. She was evaluated for CD, but resulted negative for anti-tTG antibodies.At the age of 4.1 years, she exhibited basal dental enamel hypoplasia, iron deficiency anaemia despite repeated iron supplementation, with persistent reduced height (-2.79 SDS), BMI (-0.76 SDS), growth velocity (-1.79 SDS) and delayed bone age (1.5 year). The CD screening was repeated and very high anti-tTG-IgA (128 IU/ml, normal values < 7 IU/ml) and anti-tTG-IgG (77 IU/ml, normal values < 7 IU/ml) values were found. HLA genotyping revealed an HLA DQ2 haplotype. A duodenal biopsy revealed severe villous atrophy with crypt hyperplasia and increased intraepithelial lymphocytes (> 40 IELs/100 epithelial cells) confirming the diagnosis of CD. A gluten-free diet was started and after only four months, her growth velocity increased from 4.83 cm/year (-1.79 SDS) to 6.53 cm/year (-0.15 SDS).In conclusion, we report the development of a positive serology for CD in an asymptomatic child with growth retardation, who previously was investigated for CD and resulted negative. Therefore, when faced with retarded growth in young patients, after excluding other malabsorption conditions and even when CD serological markers are negative, the paediatric endocrinologist should request HLA genotyping, before the intestinal biopsy, in order to check for the presence of risk alleles.
A Report of Two Cases of Age-Related Changes in Cervical Morphology in Postmenopausal Women with Vaginal Adenosis
Authors: Marguerite B Vigliani
Journal: Case Rep Obstet Gynecol (2017)
MeSH terms: Case Reports

This paper presents two cases of women who had extensive vaginal adenosis from prenatal DES exposure, extending almost halfway down the vaginal canal. Both women were followed for decades with annual exams and Pap smears until after menopause. Clinical examination in both cases initially showed an absent pars vaginalis of the cervix, vaginal adenosis, and shallowness of the fornices. Several decades of annual exams showed these stigmata of DES exposure gradually disappear as the upper vagina progressively contracted. After menopause the upper vagina in both cases transformed into what appeared to be a normal cervix with all adenosis involuted into a normal endocervical canal. A timeline was created to show the morphological changes that were observed over time. This timeline illustrates how severe vaginal stenosis above the level of the squamocolumnar junction developed in middle age and was followed in the postmenopause by fusion of the upper vaginal walls in the midline resulting in the appearance of a normal, but prolapsed, cervix.
An Unexpected Case Report of Adrenal Lymphangioma: Mimicking Metastatic Tumor on Imaging in a Patient With Pancreatic Cancer
Authors: Shang Wan, Xijiao Liu, Bole Tian, Dan Cao, Mao Li, Yuhao He, Bin Song
Journal: Front Endocrinol (Lausanne) (2021)
Keywords: adrenal tumor, computed tomography, differential diagnosis, lymphangioma, magnetic resonance imaging, pancreatic cancer
MeSH terms: Adrenal Gland Neoplasms / diagnostic imaging, Carcinoma, Pancreatic Ductal / diagnostic imaging, Lymphangioma / diagnostic imaging, Magnetic Resonance Imaging / methods, Tomography, X-Ray Computed / methods, Case Reports, Adrenal Gland Neoplasms / surgery, Aged, Carcinoma, Pancreatic Ductal / surgery, Diagnosis, Differential, Humans, Lymphangioma / surgery, Male

Adrenal lymphangioma is a very rare benign lesion worldwide and remains challenging for early diagnosis, especially when the patient has some complicated clinical disease. This is an unusual case of a 68-year-old man who was admitted to our hospital with a history of pancreatic tumor. Computed tomography (CT) images and subsequent magnetic resonance imaging (MRI) revealed a mass located in the left adrenal gland, presenting a similar enhancement pattern of the pancreatic tumor, and according to the imaging features, the patient was suspected to have an adrenal metastatic tumor originating from the pancreatic tumor. The patient underwent a surgical resection of the pancreatic tumor and the left adrenal gland. The pathologic diagnosis proved to be lymphangioma deriving from the left adrenal gland. This is the first report presenting an atypical adrenal lymphangioma mimicking a metastatic tumor of pancreatic origin, which might be suggestive in the diagnosis of adrenal lesions and the subsequent clinical treatment, especially when patient has a particular medical history. As we know, imaging examination is helpful for accurate preoperative diagnosis; however, the diagnosis of malignant tumor solely based on imaging procedures should be made cautiously by radiologists.
Spontaneous resolution of post-traumatic chronic subdural hematoma: a case report
Authors: Hakan Yilmaz, Osman Boyali, Ibrahim Burak Atci, Umit Kocaman
Journal: Pan Afr Med J (2017)
Keywords: antiaggregation therapy, chronic subdural hematoma, spontaneous resolution
MeSH terms: Craniocerebral Trauma / complications, Hematoma, Subdural, Chronic / diagnosis, Case Reports, Hematoma, Subdural, Chronic / etiology, Hematoma, Subdural, Chronic / physiopathology, Humans, Male, Middle Aged, Time Factors

Chronic subdural hematomas often occurs in late middle and old age following trivial head trauma. Surgical intervention is the first treatment option in chronic subdural hematomas which compressed the cerebral parenchym. Hematoma may be calcified or ossified in untreated patients. Spontaneous resolution of post-traumatic chronic subdural hematoma is a rare event. Spontaneous resolution is rarer if the subdural hematoma is bilateral. In the literature, this condition is reported mostly in patients with idiopathic thrombocytopenic purpura. Here, we present a case of spontaneously resolved post-traumatic bilateral chronic subdural hematoma within a period of one month in a 55-year-old male and we discuss the probable mechanisms of pathophysiology in the spontaneous resolution of chronic subdural hematoma.
Ovarian tumor and glomerulopathies: case report and review of the literature
Authors: Nawal Benabdellah, Hassan Izzedine, Yassamine Bentata, Intissar Haddiya
Journal: Pan Afr Med J (2019)
Keywords: glomerulopathy, nephrotic syndrome, ovarian tumor
MeSH terms: Nephrosis, Lipoid / diagnosis, Nephrotic Syndrome / diagnosis, Ovarian Neoplasms / diagnosis, Teratoma / diagnosis, Case Reports, Review, Female, Humans, Magnetic Resonance Imaging, Middle Aged, Nephrosis, Lipoid / etiology, Nephrotic Syndrome / etiology, Ovarian Neoplasms / complications, Ovarian Neoplasms / therapy, Proteinuria / etiology, Remission Induction, Teratoma / complications, Teratoma / therapy, Tomography, X-Ray Computed, Teratoma, Ovarian

We describe a patient who developed nephrotic syndrome in the setting of ovarian tumor. A kidney biopsy showed minimal change nephropathy (MCN). CT scan and MR imaging followed by surgery lead to diagnostic of ovarian dermoid cyst. Surgery combined with corticosteroids resulted in a complete remission of nephrotic syndrome with disappearance of proteinuria after 3 weeks. Ten other cases of ovarian tumor associated with glomerulopathy are reviewed. This is the second case of an ovarian teratoma associated with MCN. Accurate history, physical examination, laboratory data, and kidney biopsy are highlighted in establishing the correct diagnosis in such patients.