OpenMed/multicare-articles huggingface dataset:
Marketing strategies of the female-only gym industry: A case-based industry perspective
Authors: Fong-Jia Wang, Chia-Huei Hsiao, Tao-Tien Hsiung
Journal: Front Psychol (2022)
Keywords: case study, fitness services, gender, innovation services, women’s health

Female customers are an important market for fitness centers. This study aims to examine successful fitness training health models used by female fitness clubs. A case study approach and the interview method were used to collect data (i.e., face-to-face interviews) regarding the marketing strategies of female fitness clubs. Purposive sampling was employed to select executives working at the headquarters of a female-only gym, and semi-structured interviews were conducted to provide a context for fitness behaviors and to discuss the business' marketing mix. Six managers at Curves (four female and two male) across six different positions were interviewed. This study found that Curves' most significant difference compared to other private fitness clubs is that it makes women feel comfortable. Through charitable activities combined with promotions, women feel as if the gym empathizes with them. This study is unique in that it is one of the first studies to explore the business model of the female fitness club. In particular, this research suggests that sports organizations should focus their services strategies on female exercise demands. The findings of this study will support the development of marketing strategies to promote the growth of women's health as a priority within the fitness industry.
Epithelial-myoepithelial carcinoma of the nasopharynx: A case report and review of the literature
Authors: Wei Zhang, Xiao-Xiao Wang, Xiao-Li Wang, Yan Zhang, Xiu-Feng Li, Yang Li, Yuan-Yuan Cai, Hui-Qi Ren, Yun-Xiang Zhang, Fu-Rong Hao
Journal: Front Oncol (2022)
Keywords: case report, concurrent chemoradiotherapy, epithelial–myoepithelial carcinoma, immunohistochemistry, nasopharynx
MeSH terms: Case Reports

Background:
Epithelial-myoepithelial carcinoma (EMCa) is a rare low-grade malignant tumor that most commonly occurs in the salivary glands, with approximately 320 cases having been reported worldwide. Here, we report the third case of EMCa occurring in the nasopharynx. Rare cases in the breast, pituitary gland, lacrimal gland, nose, paranasal sinus, nasal cavity, trachea and bronchus, lung, and even the pleura mediastinalis have also been reported. Histopathology and immunohistochemistry are useful for confirming the diagnosis of EMCa, which is characterized by biphasic tubular structures composed of inner ductal and outer clear myoepithelial cells and stains for different markers in each layer. However, because of the rarity of EMCa, the clinicopathological characteristics and treatment of these patients remain unclear.
Case presentation:
We report a rare case of EMCa of the nasopharynx. A 51-year-old man presented with a 5-month history of pain while swallowing and aggravation accompanied by right ear tinnitus lasting for 1 month. Nasopharyngoscopy and magnetic resonance imaging (MRI) of the nasopharynx and neck revealed a 5.6 cm × 3.4 cm × 3.1 cm mass in the nasopharyngeal space, invasion of the right cavernous sinus, and lymph node enlargement in the right retropharyngeal space. On 17 April 2019, based on the histopathological and immunohistochemical features, a final diagnosis of EMCa of the right nasopharynx was made. The patient underwent concurrent chemoradiotherapy (CCRT), and his symptoms were relieved after treatment. On 10 January 2022, nasopharynx MRI and biopsy revealed local recurrence, but chest and abdominal computed tomography (CT) showed no obvious signs of metastasis. The local recurrence-free survival (LRFS) period was 33 months.
Conclusion:
To the best of our knowledge, this is the third reported case of EMCa in the nasopharynx and the only case of EMCa in the nasopharynx treated with CCRT, and a partial response was achieved. Therefore, to improve the quality of life and prognosis of patients with unresectable tumors, we believe that CCRT is a suitable option. Further clinical observations are required to elucidate the pathophysiology and prognosis of EMCa.
Synchronized multiple regression of diagnostic radiation-induced rather than spontaneous: disseminated primary intracranial germinoma in a woman: a case report
Authors: Yuichiro Yoneoka, Itaru Tsumanuma, Shinya Jinguji, Manabu Natsumeda, Yukihiko Fujii
Journal: J Med Case Rep (2011)

Introduction:
Examples of the spontaneous regression of primary intracranial germinomas can be found in the literature. We present the case of a patient with disseminated lesions of primary intracranial germinoma which synchronously shrunk following diagnostic irradiation. We will discuss whether this regression was spontaneous or radiation-induced.
Case presentation:
A 43-year-old Japanese woman presented to our hospital complaining of memory problems over a period of one year and blurred vision over a period of three months. Following magnetic resonance imaging, she was found to have a massive lesion in the third ventricle and small lesions in the pineal region, fourth ventricle, and in the anterior horn of the left lateral ventricle. Prior to an open biopsy to confirm the pathology of the lesions, she underwent a single cranial computed tomography scan and a single cranial digital subtraction angiography for a transcranial biopsy. Fourteen days after the first magnetic resonance image - 12 and eight days after the computed tomography scan and digital subtraction angiography, respectively - a pre-operative magnetic resonance image was taken, which showed a notable synchronous shrinkage of the third ventricle tumor, as well as shrinkage of the lesions in the pineal region and in the fourth ventricle. She did not undergo steroid administration until after a biopsy that confirmed the pathological diagnosis of pure germinoma. She then underwent whole craniospinal irradiation and went into a complete remission.
Conclusions:
In our case report, we state that diagnostic radiation can induce the regression of germinomas; this is the most reasonable explanation for the synchronous multiple regression observed in this case of germinoma. Clinicians should keep this non-spontaneous regression in mind and monitor germinoma lesions with minimal exposure to diagnostic radiation before diagnostic confirmation, and also before radiation treatment with or without chemotherapy begins.
A rare tumour of pancreas-Case report
Authors: P Sai Krishna, A Sivasankar
Journal: Int J Surg Case Rep (2020)
Keywords: case report, imaging, pancreatic schwannoma, ultrasonography
MeSH terms: Case Reports

Introduction:
Pancreatic schwannomas are very rare neoplasm arising from Schwann cells that present in the nerve sheath. Schwannoma usually occur in the extremities but can also be found in the trunk, head and neck, retroperitoneum, mediastinum, pelvis and rectum.
Presentation of case:
We briefly describe a 30-year-old female patient with upper abdominal pain and on examination by ultrasound and Computed tomography of abdomen revealed a solid tumor arising from body of the pancreas. A laparoscopic splenic vessel preserving distal pancreatectomy (kimura) was performed.
Discussion:
Approximately only 50 cases reported in the literature and none of these cases were diagnosed as schwannoma preoperatively. CT scan is often useful to establish pancreatic lesion which usually demonstrate hypodense lesion with encapsulation CONCLUSION: Although the incidence of pancreatic schwannoma is low, it must be considered as one possibility in the differential diagnosis of mass lesions in the pancreas and whenever possible especially in large tumors surgical resections should be considered due to increased chance of transformation to malignancy.
Seromucinous Hamartoma of the Lateral Nasal Wall with Infiltration of the Orbit: A Rare Case Report and Review of the Literature
Authors: Lentiona Basiari, Maria Michali, Ioannis Komnos, Georgios Tsirves, Victoria Tsoumani, Ioannis Kastanioudakis
Journal: Case Rep Otolaryngol (2023)
MeSH terms: Case Reports

Seromucinous hamartoma is a rare benign glandular proliferation arising from the respiratory epithelium of the sinonasal tract and nasopharynx. It was described for the first time in 1974 by Baillie and Batsakis. Since then, few cases have been reported in the literature with most of them occurring in the posterior nasal septum. We report the case of a 52-year-old woman that presented to our department with left periorbital edema, pain, and dacryorrhea due to seromucinous hamartoma arising from the left inferior turbinate and extending through the lateral nasal wall into the maxilla, the nasolacrimal duct, and the orbit. Endoscopic medial maxillectomy and endoscopic transnasal orbital tumor resection were performed. The patient remains symptom-free for 16 months, till her most recent follow-up. Seromucinous hamartoma of the nasal cavity is an exceedingly rare diagnosis, especially in the lateral nasal wall. It should be included in the differential diagnosis of nasal tumors. According to the literature review, this is the first case report of seromucinous hamartoma with orbit infiltration. Endonasal endoscopic resection is the treatment of choice.
Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis
Authors: Seyedeh Maryam Hosseini, Mojtaba Abrishami, Elham Barashki, Ghodsieh Zamani
Journal: Case Rep Ophthalmol Med (2021)
MeSH terms: Case Reports

Purpose:
Herein, we report a case of primary intraocular lymphoma (PIOL) with the first presentation of bilateral Epstein-Barr virus- (EBV-) associated panuveitis. Case Presentation. A 69-year-old male was referred with a three-day history of blurred vision and pain and redness in his left eye following cataract surgery. Examination revealed panuveitis, vitritis, and necrotizing retinitis with retinal hemorrhage. A month later, the right eye was also involved. Polymerase chain reaction-based analysis of the vitreous sample was positive for EBV, and cytological evaluation was compatible with the diagnosis of B-cell lymphoma. A significant improvement was observed following serial intravitreal rituximab and methotrexate injections. The central nervous system and lungs were involved after 6 months, and the patient expired despite systemic chemotherapy.
Conclusion:
There may be an association between EBV panuveitis and primary intraocular B-cell lymphoma.
Fibrosing mediastinitis with pulmonary hypertension as a complication of pulmonary vein stenosis: A case report and review of the literature
Authors: Yidan Li, Xiangli Meng, Yidan Wang, Yuanhua Yang, Xiuzhang Lu
Journal: Medicine (Baltimore) (2018)
MeSH terms: Hypertension, Pulmonary / etiology, Mediastinitis / etiology, Sclerosis / etiology, Stenosis, Pulmonary Vein / complications, Case Reports, Review, Humans, Male, Middle Aged, Mediastinal Fibrosis

Introduction:
Fibrosingmediastinitis (FM) is caused by a proliferation of fibrous tissue in the mediastinum encasing the mediastinal viscera that results in compression of mediastinal bronchovascular structures. Pulmonary hypertension (PH) is a severe complication of FM caused by extrinsic compression of pulmonary blood vessels.
Case presentation:
Here, we present the case of a 47-year-old man who presented with a 10-year history of progressive hemoptysis and a 2-year history of shortness of breath, in whom a diagnosis of FM was made. Occlusion of the superior pulmonary veins was noted, with stenosis of the inferior pulmonary veins, leading to PH. Because the patient was a poor candidate for interventional catheterization, the preferred treatment for FM, his PH has been managed with diuretics, and he remains stable.
Conclusions:
FM is a serious, potentially life-threatening condition that is best managed in specialized centers.
Transection of gut loop due to post-operative adhesions
Authors: Naeem Liaqat, Sajid Hameed Dar
Journal: APSP J Case Rep (2013)
Keywords: adhesive bowel disease, intestinal obstruction, transection of gut
MeSH terms: Case Reports

Transection of gut due to adhesive band is an unusual complication of adhesive bowel disease. A 2-year old female presented with signs and symptoms of intestinal obstruction. Eight months earlier she underwent laparotomy for excision of duplication cyst of ileum. Exploratory laparotomy performed during current admission showed complete transection of gut.
Case Report: Pink Urine Syndrome Following Exposure to Propofol: A Rare, Impressive but Benign Complication
Authors: Fangwei Zhang, Xing Zhu, Hongbo Zhang, Lin Xu, Weiguo Wu, Xuelei Hu, Haipeng Zhou, Penghui Wei, Jianjun Li
Journal: Front Pharmacol (2021)
Keywords: complications, non-obese patients, pink urine syndrome, propofol, uric acid metabolism disorders
MeSH terms: Case Reports

Drug-induced changes in urine color induced by drugs may have clinical significance. Pink urine syndrome (PUS), which has been associated with urinary uric acid (UA) disorders, is most frequently reported in patients with morbid obesity undergoing gastric bypass surgery and/or from propofol anesthesia use in those who potentially have preexisting UA metabolism disorders. However, PUS has rarely occurred following exposure to propofol in non-obese patients, and literature on long-term follow-up after PUS is scarce. We report a case of PUS induced by propofol in a previously healthy non-obese woman after undergoing thoracoscopic wedge resection of pulmonary nodules under general anesthesia using propofol. The patient suddenly developed pink urine 4 h after surgery. A pink sediment rapidly precipitated at the bottom of the test tube following centrifugation of the urine. Amorphous, colorless UA-like crystals were identified under a polarizing microscope. The diagnosis of PUS was confirmed by examining the urinary UA concentration. The patient recovered and as followed-up for 1 month, during which she did not experience any urinary complications. To our knowledge, this is the first report to describe in detail a case of PUS caused by propofol in a non-obese patient with follow-up. PUS is usually benign and can resolve by rapidly on administering lactated Ringer's solution; however, the potential risk of urinary complications, particularly UA lithiasis, should be fully realized.
Multimodality Surgical Approach in Management of Laryngotracheal Stenosis
Authors: Ashfaque Ansari, Annju Thomas
Journal: Case Rep Otolaryngol (2018)
MeSH terms: Case Reports

Introduction:
Postintubation laryngotracheal stenosis requires a precise diagnosis and an experienced operator in both endoscopic and surgical treatment. This report presents surgically treated cases of laryngotracheal stenosis secondary to long-term intubation/tracheostomy with review of the literature.
Materials and methods:
In this retrospective study, we present 5 cases (a 23-year-old male, 13-year-old male, 22-year-old male, 19-year-old male, and 33-year-old female) of postintubation/tracheostomy laryngotracheal (glottic/subglottic) stenosis in the years 2016 and 2017. Each patient was managed differently. Intubation characteristics, localization of stenosis, surgical technique and material, postoperative complications, and survival of patients were recorded.
Results:
The site of stenosis was in the subglottis in 4 patients and glottis in 1 patient. The mean length of the stenosis was greater in the postintubation group. Postintubation stenosis had a mean duration of intubation of 6.8 days, compared to 206.25 days of cannulation following tracheostomies. Each patient underwent an average of 2 procedures during their treatment course. One patient underwent open surgical anastomosis because of recurrent subglottic stenosis after multiple treatments. Phonation improved immediately in almost all except in the patient who underwent only endoscopic dilatation.
Discussion:
The reasons for laryngeal stenosis and its delayed diagnosis have been reviewed from the literature. Suture tension should be appropriate, and placement of the suture knot outside the trachea minimizes formation of granulation tissue. The published reports suggest that resection by endoscopy with laser and open technique resection and primary anastomosis are the best treatment modality so far as the long-term results are concerned.
Conclusion:
Resection of stenotic segment by open surgical anastomosis and laser-assisted resection is a safe option for the treatment of subglottic stenosis following intubation without the need for repeated dilation. Endoscopic dilation can be reserved for unfit patients.
New Approach for the Calculation of the Intraocular Lens Power Based on the Fictitious Corneal Refractive Index Estimation
Authors: Joaquín Fernández, Manuel Rodríguez-Vallejo, Javier Martínez, Ana Tauste, David P Piñero
Journal: J Ophthalmol (2019)

Purpose:
To identify the sources of error in predictability beyond the effective lens position and to develop two new thick lens equations.
Methods:
Retrospective observational case series with 43 eyes. Information related to the actual lens position, corneal radii measured with specular reflection and Scheimpflug-based technologies, and the characteristics of the implanted lenses (radii and thickness) were used for obtaining the fictitious indexes that better predicted the postoperative spherical equivalent (SE) when the real effective lens position (ELP) was known. These fictitious indexes were used to develop two thick lens equations that were compared with the predictability of SRK/T and Barrett Universal II.
Results:
The SE relative to the intended target was correlated to the difference between real ELP and the value estimated by SRK/T (ΔELP) (r = -0.47, p=0.002), but this only predicted 22% of variability in a linear regression model. The fictitious index for the specular reflection (n k) and Scheimpflug-based devices (n c) were significantly correlated with axial length. Including both indexes fitted to axial length in the prediction model with the ΔELP increased the r-square of the model up to 83% and 39%, respectively. Equations derived from these fictitious indexes reduced the mean SE in comparison to SRK/T and Barrett Universal II.
Conclusions:
The predictability with the trifocal IOL evaluated is not explained by an error in the ELP. An adjustment fitting the fictitious index with the axial length improves the predictability without false estimations of the ELP.
Fusion of the genes EWSR1 and PBX3 in retroperitoneal leiomyoma with t(9;22)(q33;q12)
Authors: Ioannis Panagopoulos, Ludmila Gorunova, Bodil Bjerkehagen, Sverre Heim
Journal: PLoS One (2015)
MeSH terms: Calmodulin-Binding Proteins / genetics, Homeodomain Proteins / genetics, Leiomyoma / genetics, Oncogene Proteins, Fusion / genetics, Proto-Oncogene Proteins / genetics, RNA-Binding Proteins / genetics, Translocation, Genetic, Case Reports, Research Support, Non-U.S. Gov't, Adult, Base Sequence, Chromosomes, Human, Pair 22, Chromosomes, Human, Pair 9, Female, Humans, In Situ Hybridization, Fluorescence, Karyotyping, Leiomyoma / pathology, Molecular Sequence Data, RNA-Binding Protein EWS, Calmodulin-Binding Proteins, EWSR1 protein, human, Homeodomain Proteins, Oncogene Proteins, Fusion, Proto-Oncogene Proteins, RNA-Binding Protein EWS, RNA-Binding Proteins, proto-oncogene protein Pbx3

Retroperitoneal leiomyoma is a rare benign smooth muscle tumor almost exclusively found in women and with histopathological features similar to uterine leiomyomas. The pathogenesis of retroperitoneal leiomyoma is unclear and next to nothing is known about the cytogenetics and molecular genetics of the tumor. We present here a retroperitoneal leiomyoma with a t(9;22)(q33;q12) as the sole karyotypic aberration. The translocation resulted in an EWSR1-PBX3 fusion gene in which exon 9 of EWSR1 (nucleotide 1320 accession number NM_013986 version 3) was in-frame fused to exon 5 of PBX3 (nucleotide 824 accession number NM_006195 version 5). The EWSR1-PBX3 fusion transcript codes for a 529 amino acids long chimeric EWSR1-PBX3 protein which contains the N-terminal transactivation part of EWSR1 and the homeodomain of PBX3. The present study, together with our previous finding of a retroperitoneal leiomyoma with t(10;17)(q22;q21) as the sole karyotypic aberration and a KAT6B-KANSL1 fusion gene, indicates that retroperitoneal leiomyomas may be characterized by fusion genes coding for chimeric proteins. However, cytogenetic and molecular heterogeneity exists in these tumors and it is too early to tell how many and which different pathways lead to retroperitoneal leiomyomagenesis.
Prosthetic Joint Infection from Carbapenemase-Resistant Klebsiella pneumoniae Successfully Treated with Ceftazidime-Avibactam
Authors: A Schimmenti, E Brunetti, E Seminari, B Mariani, P Cambieri, P Orsolini
Journal: Case Rep Infect Dis (2018)
MeSH terms: Case Reports

Antimicrobial resistance in Gram-negative bacteria, particularly Enterobacteriaceae, has become a leading cause of morbidity and mortality and a serious public health concern. Gram-negative bacteria carrying extended-spectrum beta-lactamase (ESBL) enzymes now represent a significant proportion of all bacteria isolated from different countries worldwide. Furthermore, the increasing number of isolates carrying carbapenemases in recent years includes multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacteria. Here, we describe what, to our knowledge, is the first case of a patient with a prosthetic joint infection from carbapenemase-resistant Klebsiella pneumoniae (CRKP) successfully treated with ceftazidime-avibactam in Italy.
Polymicrobial Necrotizing Fasciitis in a Dog: The Involvement of Macrococcus caseolyticus, Proteus mirabilis, and Escherichia coli
Authors: Obed Danso Acheampong, Ben Enyetornye, Dominic Osei
Journal: Case Rep Vet Med (2021)
MeSH terms: Case Reports

A male mixed breed dog was presented with two large wounds, extending the epidermis, dermis, and fascia: one at the dorsum of the thoracolumbar region and the other at the lumbosacral area. Lesions had extended inconspicuously to the dorsum of thorax affecting a large area, which showed regions with necrotic and crepitating foci after shaving. Based on histopathological and bacterial culture examinations, polymicrobial necrotizing fasciitis (NF) was diagnosed. Using the Bruker MALDI Biotyper identification technique, Macrococcus caseolyticus, Proteus mirabilis, and Escherichia coli were identified. Hitherto, there is no report on these bacteria linking them simultaneously to NF in a dog. In addition, the authors highlight other microbes associated with NF in humans and animals.
Presence of Anti-Glomerular Basement Membrane Antibodies and Myeloperoxidase Anti-Neutrophilic Cytoplasmic Antibodies in a Case of Rapidly Progressive Glomerulonephritis
Authors: Gaurang P Mavani, Max Pommier, Sandar Win, Michael F Michelis, Jordan Rosenstock
Journal: Front Med (Lausanne) (2015)
Keywords: rpgn, anti-gbm antibody, anti-mpo antibody, cyclophosphamide, plasmapheresis
MeSH terms: Case Reports

A 69-year-old male had initially presented with low-grade proteinuria, microhematuria, and a positive myeloperoxidase anti-neutrophilic antibody (ANCA). He subsequently developed deterioration of kidney function and developed uremic symptoms. Creatinine was 486.2 μmol/L (5.5 mg/dL). Anti-MPO was positive (titer >8 U, normal <0.4). He was clinically diagnosed with rapidly proliferative glomerulonephritis most likely due to ANCA vasculitis. He received three doses of pulse methylprednisolone therapy. Kidney biopsy showed pauci-immune glomerulonephritis. Immunofluorescence was positive for faint linear IgG staining of glomerular basement membrane (GBM). Anti-GBM antibody was positive 2.1 U (normal <1). He was started on high-dose oral steroids; monthly intravenous cyclophosphamide and plasmapheresis were also initiated. His symptoms improved and creatinine is 247.5 μmol/L (2.8 mg/dL). His repeat anti-GBM antibody was negative. This is a rare case of rapidly progressive glomerulonephritis due to dual MPO-ANCA antibodies and anti-GBM antibodies (DAV).