OpenMed/multicare-articles huggingface dataset:
Amanita bisporigera-Induced Hepatic Failure: A Fatal Case of Mushroom Ingestion
Authors: Anthony Nici, Sang Kim
Journal: Case Reports Hepatol (2011)

Wild mushroom poisoning from the genus Amanita is a medical emergency, with Amanita phalloides being the most common offender. Patients may complain of nausea, vomiting, diarrhea and/or abdominal pain. If not aggressively treated, fulminant hepatic failure may develop within several days of ingestion. In this case report, a patient poisoned with Amanita bisporigera is described, along with the typical clinical presentation, patient outcomes, and treatment options for dealing with an Amanita mushroom poisoning.
Case report: Levodopa-responsive parkinsonism with akinetic mutism after ventriculo-peritoneal shunt
Authors: Ying Zhang, Ping Li, Jifeng Zhang, Chunyang Li, Peng Sun, Fujun Li, Zhuomin Jiao
Journal: Front Neurol (2023)
Keywords: 18f fluorodeoxyglucose, akinetic mutism, levodopa, parkinsonism, ventriculo-peritoneal shunt
MeSH terms: Case Reports

Background:
Parkinsonism and akinetic mutism (AM) following ventriculo-peritoneal shunt (VPS) without underdrainage used to be considered rare, but may be underdiagnosed in daily clinical practice. Although the pathophysiology is still unclear, in several case reports, the parkinsonism and AM after VPS shows responsiveness to dopaminergic treatment.
Case presentation:
We report a 19-year-old male that presented with severe parkinsonism and AM after VPS. Meanwhile, 18F-FDG-PET showed a cortical and subcortical hypometabolism. Fortunately, levodopa dramatically improved patient's symptoms and brain hypometabolism. This report provides support for the possibility that dopamine deficiency inhibits brain metabolism, and further elucidates the pathogenesis of parkinsonism and AM.
Conclusion:
This report highlights the presentation of a treatable parkinsonism and points out that Levodopa and/or dopamine agonist should be the first choice if the patients develop parkinson-like symptoms after VPS.
Cutaneous lesions as the first manifestation of breast cancer: a rare case
Authors: Harwin Prestasia Putra, Khairuddin Djawad, Airin Riskianty Nurdin
Journal: Pan Afr Med J (2020)
Keywords: breast cancer, case report, cutaneous metastasis, first manifestation
MeSH terms: Breast Neoplasms / diagnosis, Skin Neoplasms / diagnosis, Case Reports, Biopsy, Breast Neoplasms / pathology, Collagen / metabolism, Female, Humans, Middle Aged, Skin Neoplasms / pathology, Skin Neoplasms / secondary, Collagen

Cutaneous metastases due to internal malignancies are rare but, in some cases, may present as the first manifestation of an undiagnosed malignancy. A 62-year-old female presented with itchy reddish patch on the left neck which spread to the left shoulder, arm, breast, and back four weeks prior to admission. Ten days later, vesicles emerged, ruptured, and ulcerated. The patient denied any history of breast lump. Skin biopsy showed diffuse dermal nests of tumor cells infiltrating to the collagen bundles and fat tissue, which was consistent with cutaneous metastasis from the breast cancer. The patient refused further workup and treatment and eventually passed away. This case showed the importance of conducting a comprehensive evaluation in cutaneous lesions presenting with early or sudden onset, rapid evolution, tendency to bleed, that do not resolve with treatment.
CO(2) Laser Surgery and Prosthetic Management for the Treatment of Epulis Fissuratum
Authors: Tarcisio José de Arruda Paes-Junior, Sâmia Carolina Mota Cavalcanti, Daniela Fernandes Figueira Nascimento, Guilherme de Siqueira Ferreira Anzaloni Saavedra, Estevão Tomomitsu Kimpara, Alexandre Luiz Souto Borges, Walter Niccoli-Filho, Paula Carolina de Paiva Komori
Journal: ISRN Dent (2011)
MeSH terms: Case Reports

The aim of this study was to present a case report of the surgical removal of hyperplasia in the oral cavity, using carbon dioxide (CO(2)) laser radiation and rehabilitation with a complete denture. Epulis fissuratum occurs in complete denture patients, because a constant irritative action induces the mucosa to grow under poorly fitting dentures. These lesions must be removed, and to avoid a relapse, new complete dentures should be made to maintain healthy surgical tissues. The clinical sequence presented in this case shows a completely edentulous patient with epulis fissuratum on the lower alveolar ridge extending to the vestibular sulcus of the anterior region of mandible. Immediate complete dentures were made prior to the lesion removal with CO(2) laser radiation, providing satisfactory results in oral function and tissue health.
A 16-Year-Old Male with Thoracic Compression following Posterior Spinal Instrumentation and Fusion for Marfan-Associated Syndromic Scoliosis
Authors: Mason Uvodich, Ross Barman, Adam Reitz, Matthew Sexton
Journal: Case Rep Orthop (2020)
MeSH terms: Case Reports

Introduction:
Marfan syndrome is an autosomal dominant disorder caused by a mutation in the FBN1 gene which affects connective tissue. The features of Marfan syndrome include many musculoskeletal abnormalities which require orthopaedic surgical intervention. Given the expansive phenotypic variations and comorbidities associated with Marfan syndrome, knowledge of perioperative risk factors and potential complications is essential.
Case:
In this case report, the authors describe a patient with Marfan syndrome who underwent spinal instrumentation and fusion from T3 to L4 for correction of syndromic scoliosis. The patient had a complicated perioperative course requiring significant fluid resuscitation and vasoactive medications to support blood pressure. He required intensive care unit level care for continued hemodynamic instability despite resuscitation in the postoperative period. Common causes of postoperative hypotension such as hypovolemic shock, sepsis, ongoing hemorrhage, and prolonged effects of anesthesia were diagnostically ruled out. Ultimately, the patient's refractory hypotension was determined to be from mechanical compression, both from prolonged intraoperative prone positioning exacerbated by pectus excavatum and from the surgically corrected spine decreasing the diameter of his thoracic cavity (as referenced by his postoperative Haller index).
Conclusion:
Mechanical compression of thoracic contents as a result of a worsening chest wall deformity can be a complication of spinal deformity correction.
The fusion band in V1: a simple ECG guide to optimal resynchronization? An echocardiographic case report
Authors: Lorella Gianfranchi, Katia Bettiol, Federico Pacchioni, Giorgio Corbucci, Paolo Alboni
Journal: Cardiovasc Ultrasound (2005)
MeSH terms: Bundle-Branch Block / diagnosis, Bundle-Branch Block / prevention & control, Cardiac Pacing, Artificial / methods, Electrocardiography / methods, Heart Failure / diagnosis, Heart Failure / prevention & control, Case Reports, Bundle-Branch Block / diagnostic imaging, Echocardiography, Heart Failure / diagnostic imaging, Humans, Male, Middle Aged, Treatment Outcome

Background:
Patients with left bundle branch block have a preserved right bundle branch conduction and the efficacy of left ventricular pacing could be explained with the fusion between artificial pulse delivered in the left lateral wall and the spontaneous right ventricular activation. Moreover, the efficacy of left ventricular pacing could be enhanced with an optimal timing between the spontaneous right ventricular activation and the left ventricular pulse.
Case presentation:
We evaluated a patient (male, 47 yrs) with surgically corrected mitral regurgitation, sinus rhythm and left bundle branch block, heart failure (NYHA class III) despite medical therapy and low ejection fraction (25%): he was implanted with a biventricular device. We programmed ventricular pacing only through the left ventricular lead. We defined what we called electrocardiographic "fusion band" as follow: programming OFF the stimulator, we recorded the native electrocardiogram and measured, through the device, the intrinsic atrioventricular interval. Then, atrioventricular interval was progressively shortened by steps of 20 ms down to 100 ms. Twelve leads electrocardiogram was recorded at each step. The fusion band is the range of AV intervals at which surface electrocardiogram (mainly in V1 lead) presents an intermediate morphology between the native left bundle branch block (upper limit of the band) and the fully paced right bundle branch block (lower limit). The patient underwent echocardiographic examination at each atrioventricular interval chosen inside the fusion band. The following parameters were evaluated: ejection fraction, diastolic filling time, E wave deceleration time, aortic velocity time integral and myocardial performance index. All the echocardiographic parameters showed an improvement inside the fusion band, with a "plateau" behaviour. As the fusion band in this patient ranged from an atrioventricular delay of 200 ms to an atrioventricular delay of 120 ms, we chose an intermediate atrioventricular delay of 160 ms, presuming that this might guarantee the persistence of fusion even during any possible physiological (autonomic, effort) atrioventricular conduction variation.
Conclusion:
In this heart failure patient with left bundle branch block, tailoring of the atrioventricular interval resynchronized myocardial contraction with left ventricular pacing alone, utilizing a sensed right atrial activity and the surface electrocardiographic pattern.
A forgotten migrated intrauterine contraceptive device is not always innocent: a case report
Authors: Ranjeet Brar, Sudeendra Doddi, Anand Ramasamy, Prakash Sinha
Journal: Case Rep Med (2010)
MeSH terms: Case Reports

The incidence of transuterine perforation and migration of intrauterine contraceptive devices (IUCDs) into the abdominal cavity has been estimated at less than 0.1%. It has been suggested that intraperitoneal IUCD have low morbidity and may be left in situ. We report the first case of closed loop small bowel obstruction due to migration of a "Saf-T-Coil" IUCD into the abdominal cavity, where it became embedded in the omentum and ultimately, 31 years after deployment, coiled both arms around a loop of ileum. This late complication underlines the dangers of intra-abdominal foreign bodies, even when chemically and biologically inert.
Supraglottic jet oxygenation and ventilation via nasopharyngeal airway for a patient with iatrogenic tracheoesophageal fistula: A case report
Authors: Yang Gu, Xiaowei Zhang, Keting Min, Juan Wei, Qing Zhou, Xin Lv, Ruowang Duan
Journal: Front Med (Lausanne) (2023)
Keywords: flexible bronchoscope, jet ventilation, nasopharyngeal airway, rigid bronchoscope, stent, supraglottic jet oxygenation and ventilation, tracheoesophageal fistula
MeSH terms: Case Reports

Background:
Iatrogenic tracheoesophageal fistula (TEF) is a rare but life-threatening condition. No consensus has been reached regarding TEF treatment, though, stenting has been gaining popularity for less invasiveness than thoracic surgery. The airway management during stent placement for TEF could be challenging.
Case presentations:
We report a patient who suffered from TEF after cardiac surgery with symptoms of persistent coughing and aspiration. He who was admitted for stent placement but ended up in failure and referred to our institution for further treatment. We successfully took advantage of the supraglottic jet oxygenation and ventilation (SJOV) during stent placement.
Conclusion:
This is the first case so far describing SJOV in complicated stenting treatment. This demonstrates that SJOV can be applied for stent placement in TEF patients with restricted airways.
A Minimal Design of a Human Infant Presence: A Case Study Toward Interactive Doll Therapy for Older Adults With Dementia
Authors: Hidenobu Sumioka, Nobuo Yamato, Masahiro Shiomi, Hiroshi Ishiguro
Journal: Front Robot AI (2021)
Keywords: doll therapy, elderly dementia care, human–robot interaction, minimal design, therapy robot

We introduce a minimal design approach to manufacture an infant-like robot for interactive doll therapy that provides emotional interactions for older people with dementia. Our approach stimulates their imaginations and then facilitates positive engagement with the robot by just expressing the most basic elements of humanlike features. Based on this approach, we developed HIRO, a baby-sized robot with an abstract body representation and no facial features. The recorded voice of a real human infant emitted by robots enhances the robot's human-likeness and facilitates positive interaction between older adults and the robot. Although we did not find any significant difference between HIRO and an infant-like robot with a smiling face, a field study showed that HIRO was accepted by older adults with dementia and facilitated positive interaction by stimulating their imagination. We also discuss the importance of a minimal design approach in elderly care during post-COVID-19 world.
The Rogue P-wave: Atrial Dissociation Following Bicaval Heart Transplantation
Authors: William A Huang, Jennifer P Woo, Noel G Boyle
Journal: J Innov Card Rhythm Manag (2019)
Keywords: atrial dissociation, bicaval, complete heart block, interatrial block, orthotopic heart transplant
MeSH terms: Case Reports

We report the first case, to our knowledge, of atrial dissociation in a patient who underwent bicaval orthotopic heart transplantation. It was believed that atrioventricular dissociation prompting pacemaker implantation likely represented donor sinus bradycardia/arrest with intact atrioventricular conduction with surgically isolated recipient atrial activity.
Multimodal ultrasonography findings of extramammary granular cell tumors: Two case reports
Authors: Meng Zhu, Huan Xu, Yujuan Chen, Yulan Peng
Journal: Front Oncol (2023)
Keywords: axillary, case reports, contrast-enhanced ultrasound, granular cell tumor, pectoralis major muscle, shear wave elasticity
MeSH terms: Case Reports

Extramammary masses are infrequently encountered in breast examinations. They may occur in the chest wall and axilla as neighbors of the breast. It is important to determine the nature of the lesion. However, some benign tumors, such as granular cell tumors (GCTs), also show malignant characteristics, which leads to misdiagnosis. To the best of our knowledge, multimodal ultrasound features of GCT have not been elucidated. We report two cases of women with GCTs encountered upon breast cancer screening; the tumor was not located in breast tissue. The first patient was a 37-year-old woman who presented with a slow-growing mass in the right breast and the GCT was located in the pectoralis major muscle. The second patient was a 52-year-old woman who presented with a palpable left axillary mass and the GCT was located in the axilla. Mammography failed to detect the masses in the two patients upon breast cancer screening. However, two-dimensional ultrasonography revealed a solid heterogeneous hypoechoic mass. Shear wave elastography showed that the masses had an increased hardness compared with the surrounding tissue. Further contrast-enhanced ultrasonography showed that the contrast patterns of the two masses were different. In case one, contrast-enhanced ultrasonography showed an inhomogeneous annular high enhancement, and the dynamic curve showed rapid enhancement and regression. In case two, contrast enhanced ultrasound showed slight enhancement around the lesion but no enhancement inside. Postoperative pathology confirmed that the GCT was benign in both cases. The patients showed no signs of recurrence at the 2-year follow-up. Here, we report two cases and present the multimodal ultrasonography findings of this tumor for the first time. Radiologists and surgeons should be aware of these imaging manifestations and include them in their differential diagnoses.
Combined Fundal and Segmental Adenomyomatosis of the Gallbladder in a Child: A Rare Case Report
Authors: Hidetoshi Kinoshita, Hiromichi Ariga, Jun Shirota, Kyosuke Sasaki, Yasuko Shibukawa, Yutaka Fukuda, Katsutoshi Nagasawa, Seiya Ogata, Hirofumi Shimizu, Michitoshi Yamashita, Hideaki Tanaka
Journal: Case Rep Pediatr (2019)
MeSH terms: Case Reports

Adenomyomatosis of the gallbladder (AMG) is characterized by mucosal hyperplasia leading to invagination through the thickened muscle layer, which is relatively common in adults, but is rare in childhood. We report a 12-year-old boy with adenomyomatosis of the gallbladder combined segmental and fundal type. This combined type is rare in adults and is first reported here in childhood. Although initial imaging with computed tomography (CT) suggested the presence of a circular solid mass-like lesion because of its rare morphology, repeated ultrasonography (US) was useful for leading to a correct diagnosis.
A Case of Hydroxocobalamin-Induced False Blood Leak Alarm on Dialysis Machine
Authors: Praveen Datar, Jasdeep Singh Sidhu, Jeevanjot Virk, Osama Mukhtar, Frances Schmidt, Vijay Gayam
Journal: J Investig Med High Impact Case Rep (2019)
Keywords: cyanide poisoning, hemodialysis, hydroxocobalamin
MeSH terms: Antidotes / therapeutic use, Clinical Alarms, Cyanides / poisoning, Hydroxocobalamin / therapeutic use, Renal Dialysis / instrumentation, Case Reports, Aged, Color, False Positive Reactions, Humans, Male, Poisoning / therapy, Antidotes, Cyanides, Hydroxocobalamin

Hemodialysis machines are equipped with a blood leak detector/alarm to prevent loss of blood following rupture of semipermeable membrane; the blood leak alarms could also be triggered by sensor malfunction or presence of air bubbles in the system. Hydroxocobalamin is a Food and Drug Administration-approved rapid-acting antidote to cyanide poisoning that converts cyanide to nontoxic cyanocobalamin. Side effects are reddish discoloration of skin and body fluids, urticarial rash, and rarely anaphylaxis. In this article, a case of false blood leak alarm following treatment of cyanide poisoning with hydroxocobalamin is reported, wherein the blood leak detector in dialysis machines prevented the patient from undergoing hemodialysis by repeatedly activating blood leak alarms. Continuous renal replacement therapy was used to overcome this problem. As the use of hydroxocobalamin increases, health care professionals should be educated about its potential to interfere with hemodialysis.
Giant Gastroschisis with Complete Liver Herniation: A Case Report of Two Patients
Authors: Wendy Jo Svetanoff, Benjamin Zendejas, Farokh R Demehri, Alex Cuenca, Bharath Nath, C Jason Smithers
Journal: Case Rep Surg (2019)
MeSH terms: Case Reports

Introduction:
There are no reported survivors of gastroschisis with complete liver herniation. We describe a case report of two patients, one of whom survived.
Case #1:
The patient was born with gastroschisis and herniation of the entire liver. Along with silo placement, the abdominal fascia was attached to an external traction system for growth. Complete closure was achieved at 5 months. Due to pulmonary hypoplasia, high-frequency ventilation was required. The patient is doing well, on a home ventilator wean, at 20 months.
Case #2:
The patient was born prematurely with gastroschisis, total liver herniation, and a defect extending to the pericardium. A silo was attached to the fascia to provide growth of the abdominal cavity. The patient developed respiratory failure, diffuse anasarca, and renal failure. She died at 38 days of life.
Discussion:
We report the first survivor of gastroschisis with complete liver herniation, contrasting it with a death of a similar case. The associated pulmonary hypoplasia may require long-term ventilation, the inflammatory response can lead to anasarca, and renal injury can occur from acute-on-chronic compartment syndrome.
Conclusion:
External fascial traction systems can help induce growth of the abdominal wall, allowing closure of the challenging abdomen. While critical care management is complex, survival is possible.
An ARFID case report combining family-based treatment with the unified protocol for Transdiagnostic treatment of emotional disorders in children
Authors: Sarah Eckhardt, Carolyn Martell, Kristina Duncombe Lowe, Daniel Le Grange, Jill Ehrenreich-May
Journal: J Eat Disord (2019)
Keywords: avoidant/restrictive food intake disorder, emotional disorders, family-based treatment, transdiagnostic, unified protocol
MeSH terms: Case Reports

Background:
This case report discusses the presentation and treatment of a nine-year-old female with a history of significant weight loss and food refusal using a combined approach of Family-Based Treatment (FBT) and the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C).
Case presentation:
The patient was diagnosed with avoidant/restrictive food intake disorder (ARFID), separation anxiety disorder, and a specific phobia of choking, and subsequently treated with a modified version of FBT, in conjunction with the UP-C. At the end of treatment, improvements were seen in the patient's weight and willingness to eat a full range of foods. Decreases in anxiety regarding eating/choking, fears of food being contaminated with gluten, and fears of eating while being away from parents were also observed.
Conclusions:
These findings highlight promising results from this combined treatment approach, referred to as FBT + UP for ARFID. Further research is needed to evaluate the use of this treatment in patients presenting with a variety of ARFID symptoms.
A novel PHEX mutation associated with vitamin D-resistant rickets
Authors: Saori Sako, Yo Niida, Kosuke Robert Shima, Yumie Takeshita, Kiyo-Aki Ishii, Toshinari Takamura
Journal: Hum Genome Var (2019)
MeSH terms: Case Reports

X-linked hypophosphatemic rickets (XLH) is the most common form of hereditary rickets. Here, we present a case of XLH associated with a novel mutation in a phosphate-regulating gene with homologies to endopeptidases on the X chromosome (PHEX). PCR-direct sequencing revealed a novel PHEX mutation in exon 22, NM_000444.6(PHEX):c.2202del [p.Asn736Ilefs*4], near the 3'-UTR region encoding the COOH-terminal extracellular domain. In silico analysis indicated that a single mutation in N736 may have caused a significant change in higher-order protein structure and function.
Diffuse Venous Malformation of the Uterus in a Pregnant Woman with Klippel-Trénaunay Syndrome Diagnosed by DCE-MRI
Authors: Nana Yara, Hitoshi Masamoto, Yuko Iraha, Akihiko Wakayama, Yukiko Chinen, Hayase Nitta, Tadatsugu Kinjo, Yoichi Aoki
Journal: Case Rep Obstet Gynecol (2016)

Background. We experienced a rare case of a pregnant woman with Klippel-Trénaunay syndrome complicated with diffuse venous malformation of the uterus. This is the first report on the usefulness of dynamic contrast-enhanced-MRI for the diagnosis of diffuse venous malformation of the uterus. Case Presentation. A 23-year-old woman presented with convulsions and talipes equinus position of both lower limbs at 11 weeks of gestation. At 27 weeks, ultrasonography demonstrated tubular echolucent spaces throughout the myometrium. Dynamic MRI at 37 weeks revealed that the myometrial lesion was enhanced slowly and showed homogeneous enhancement even on a 10 min delayed image. Taken together with unilateral foot hypertrophy, varices, and port-wine stain, the patient was diagnosed as having Klippel-Trénaunay syndrome complicated with diffuse venous malformation of the pregnant uterus. The patient underwent elective cesarean section because of severe dystonia. The lower uterine segment was thickened and heavy venous blood flow was observed at the incision. Histological diagnosis of the myometrial biopsy specimen was venous malformation. Conclusions. Both diffuse venous malformation and Klippel-Trénaunay syndrome during pregnancy can involve considerable complications, in particular, massive bleeding during labor. Women who suffer from this syndrome should be advised about the risk of complications of pregnancy.