OpenMed/multicare-articles huggingface dataset:
Synchronous Choriocarcinoma and Epithelioid Trophoblastic Tumor Concurring at the Cesarean Scar: A Case Report and Review of the Literature
Authors: Chunyan Zeng, Shadi Rezai, Alexander C Hughes, Cassandra E Henderson, Juan Liu
Journal: Case Rep Obstet Gynecol (2019)
MeSH terms: Case Reports

We present a complicated case of recurrence of gestational trophoblastic neoplasms (GTN), mixed ETT and choriocarcinoma at an abdominal cesarean scar. This tumor consisted of typical morphologic and immunophenotypic features of ETT and choriocarcinoma. The tumor recurred despite the patient undergoing chemotherapy. The patient had this abdominal mass resected three times. The elements of ETT and coexisting choriocarcinoma varied each time. Due to re-recurrence of the tumor, the following decisions had been made: total abdominal hysterectomy, bilateral salpingectomy, right-sided inguinal lymph node biopsy. At the time of this report, recurrence was negative.
Variations in Aggressive and Indolent Behaviour of Central Dentinogenic Ghost Cell Tumor
Authors: Radhika Manoj Bavle, Sudhakara Muniswamappa, Soumya Makarla, Reshma Venugopal
Journal: Case Rep Dent (2020)
MeSH terms: Case Reports

Among the aggressive odontogenic tumors, a few tumors generally ameloblastomas, carry a connotation of being aggressive. But, a rare tumor like central dentinogenic ghost cell tumor (DGCT) can be equally aggressive with a propensity for recurrence. The two cases discussed in this article are divergent in behaviour with features such as presentation, seen in early decades as central intraosseous tumors in the maxilla and mandible. The first case describes an aggressive DGCT, associated with impacted tooth and odontome which showed recurrence into a large solid tumor within a year. The second case arose in accordance with a partially erupted molar which was comparatively innocuous and less aggressive. Both the cases exhibited classic histopathological features. These two unconventional cases of DGCT with a follow-up are being reported here to highlight the variation in behaviour and presentation and also to understand the aggressive nature of the tumor.
Omental rhabdomyosarcoma (primary rhabdoid tumor of greater omentum): a rare case report
Authors: Priyank Pathak, Mayank Nautiyal, P K Sachan, Nadia Shirazi
Journal: Surg Case Rep (2015)
Keywords: greater omentum, rhabdomyosarcoma

The greater omentum is an uncommon location for primary tumors. Metastatic tumors of the omentum are common. In contrast, primary tumors of the omentum are very rare. Sporadic cases of primary rhabdomyosarcoma (RMS) arising in the abdomen have been reported, but these cases are limited almost exclusively to the pediatric population. We report a well-documented case of primary intra-abdominal RMS in a 21-year-old man who presented with complaints of abdominal pain and lump in left hypochondrium region. Imaging revealed it to be a large mass in the left hypochondrium region displacing the bowel loops. Further investigations revealed omental RMS. The mass had originated from the greater omentum and was excised. Our case is doing well and is presently receiving chemotherapy.
Leclercia adecarboxylata Cholecystitis with Septic Shock in Immunocompetent Patient
Authors: Nooraldin Merza, John Lung, Ahmed Taha, Ahmed Qasim, Jill Frost, Tarek Naguib
Journal: Case Rep Crit Care (2019)
MeSH terms: Case Reports

L. adecarboxylata is a Gram-negative rod previously named Escherichia adecarboxylata, isolated as normal flora in the gut of animals including human stool. Most reported cases refer to immunocompromised patients with polymicrobial infections and water environments. Here we present a case of 51-year-old immunocompetent female presented with nausea, vomiting, malaise, and subjective fever for few days. On examination, she was drowsy but arousable and oriented to person, place, time, and situation. Her abdomen was tender globally and more tender in the epigastric area. Vitals showed a temperature of 37°C, pulse of 110 beats/min, blood pressure of 75/50 mmHg, and oxygen saturation of 91% on room air. An HIV panel and hepatitis panel were negative. Liver and gallbladder ultrasound was performed, revealing multiple nonmobile stones with shadowing noted within the gallbladder sac, a thickened gallbladder wall, and a moderate amount of pericholecystic fluid. Broad spectrum antibiotics, crystalloid fluids, and vasopressors were initiated. A few hours after admission she developed respiratory failure for which she underwent endotracheal intubation. An ultrasound guided gallbladder drain was performed. Culture of the biliary fluid yielded pure growth of pan-sensitive L. adecarboxylata; antibiotics were narrowed accordingly. The patient was on the maximum doses of vasopressin, norepinephrine, and epinephrine with a blood pressure of 75/45 and a mean arterial pressure of 51. She passed away on the fourth day of admission.
Cantrell Syndrome-A Rare Complex Congenital Anomaly: A Case Report and Literature Review
Authors: Claudiu Mărginean, Cristina Oana Mărginean, Liliana Gozar, Lorena Elena Meliţ, Horaţiu Suciu, Horea Gozar, Andrada Crişan, Manuela Cucerea
Journal: Front Pediatr (2018)
Keywords: cantrell syndrome, ectopia cordis, fetal screening, prenatal diagnosis, ultrasound examination
MeSH terms: Case Reports

Cantrell syndrome (CS) or pentalogy of Cantrell is defined as a rare condition involving a midline anterior abdominal wall defect, a distal sternal cleft, a defect of the anterior diaphragm, and a defect of the apical pericardium with pericardio-peritoneal communication, as well as intracardiac anomalies. We report the case of a male newborn with type 2 CS diagnosed during intrauterine life based on ultrasonographic evaluation. Clinical examination at birth revealed an abdominal wall defect with extrathoracic displacement of the heart and a diastasis of the sagittal suture. Postnatal echocardiography revealed tricuspid atresia, partial extrathoracic and extra-abdominal displacement of the heart and liver, a large ventricular septal defect, severe subpulmonary stenosis, hypoplasia of the pulmonary artery, and a large hourglass-shaped left ventricle secondary to narrowing of the heart at the level of its extrathoracic displacement. Computed tomography showed additional abnormalities including increased left ventricular volume with extrathoracic apical aneurysmal dilatation below the xiphoid process at the level of anterior abdominal wall, a hypoplastic right ventricle, partial transparietal herniation of the left hepatic lobe adjacent to a left ventricular diverticulum, and an adrenal hematoma. The newborn received intensive medical management during his first week of life; however, surgical management had to be postponed owing to his unstable condition. Eventually, it was performed on the 14th day of life, but unfortunately, the newborn died shortly after the procedure.
Neonatal Sacrococcygeal Neuroblastoma Mimicking a Teratoma
Authors: Leticia Gely, Humberto Lugo-Vicente, María Correa-Rivas, Kary Bouet, Zayhara Reyes Bou, Mohammed Suleiman, Inés García
Journal: Case Rep Pediatr (2017)
MeSH terms: Case Reports

We reported the first case of a congenital intrapelvic presacral neuroblastoma in Puerto Rico managed in the early neonatal period. The preoperative diagnosis was a sacrococcygeal teratoma Altman stage IV classification. This case confirms the importance of a comprehensive physical examination and observation of low-risk newborn infants with a history of adequate prenatal care and an unremarkable fetal ultrasonogram during pregnancy.
A Case of Fungemia Caused by Postoperative Chronic Lumbar Intervertebral Disc Infection
Authors: Rui Zheng, Taicheng Jin, Rui Tao, Ning Xu
Journal: Case Rep Surg (2022)
MeSH terms: Case Reports

Postoperative surgical site infection is one of the serious postoperative complications of spine surgery, especially fungal infections. Late-stage surgical site fungal infections often lack typical clinical symptoms and have a variable clinical presentation. In this case, the patient was a senior patient with usually only tolerable pain and discomfort, which was detected 2 years after the first surgery. Such cases are even rarer for fungal bloodstream infections caused by delayed postoperative chronic fungal osteomyelitis and deserve further study for early identification and intervention to minimize harm.
A Patient Infected with SARS-CoV-2 Presenting with Complete Heart Block
Authors: Bindu Gyawali, Bikash Baral, Sangam Shah, Sutap Yadav, Chandra Mani Poudel
Journal: Case Rep Cardiol (2021)
MeSH terms: Case Reports

Complete heart block is a rare presentation in a patient with COVID-19 infection that may result when the virus enters the myocardial cell by the angiotensin-converting enzyme-2 receptor. Here, we report a case of forty-nine-year male with COVID-19 with complete heart block (CHB).
A Wandering Abdominal Mass in a Neonate: An Enteric Duplication Cyst Mimicking an Ovarian Cyst
Authors: Shigeo Iijima
Journal: Case Rep Pediatr (2017)
MeSH terms: Case Reports

Enteric duplication cysts are rare congenital anomalies that are prenatally diagnosed through antenatal ultrasonography (US). In female patients, however, attention must be paid since these formations might be confused with ovarian cysts. Herein, we present a case of a low birth weight female infant with an enteric duplication cyst. A cystic lesion was detected in the right abdomen of the fetus on antenatal US and magnetic resonance imaging (MRI). Serial US and MRI examinations performed after birth showed a single cyst that wandered from side to side in the abdomen; the initial diagnosis was thought to be an ovarian cyst. During laparotomy, however, it was found to be an enteric duplication cyst with volvulus. To our knowledge, there has been no report of an enteric duplication cyst presenting as a wandering abdominal mass. Our experience indicates that early intervention is necessary for patients who have a wandering abdominal mass to avoid complications and urgent surgery, whether it is an ovarian cyst or an enteric duplication cyst.
Case report: Schnitzler-like syndrome without monoclonal gammopathy
Authors: Anna Sophie Wesselmann, Axel Künstner, Anke Fähnrich, Christian Rose, Peter Lamprecht, Hauke Busch, Ralf J Ludwig, Andreas Recke
Journal: Front Immunol (2023)
Keywords: schnitzler’s syndrome, autoinflammation, case report, gammopathy, late-onset autoinflammation
MeSH terms: Exanthema, Paraproteinemias, Schnitzler Syndrome / diagnosis, Schnitzler Syndrome / drug therapy, Schnitzler Syndrome / pathology, Skin Diseases, Urticaria, Case Reports, Research Support, Non-U.S. Gov't, Humans, Interleukin 1 Receptor Antagonist Protein / therapeutic use, Interleukin 1 Receptor Antagonist Protein

Schnitzler syndrome is a rare autoinflammatory disorder characterized by urticarial rash, joint pain, recurrent fever, leucocytosis, elevated C-reactive protein (CRP) and serum amyloid A (SAA), and monoclonal IgM or IgG gammopathy. According to the Strasbourg criteria, both urticarial rash and gammopathy are mandatorily required for the diagnosis of Schnitzler's syndrome. However, incomplete variants lacking either skin symptoms or monoclonal gammopathy have also been described. Here, we report a case in which the diagnosis of Schnitzler-like syndrome was made despite the absence of gammopathy, based on neutrophilic dermal inflammation, episodic and excessive increase in inflammatory parameters, and prompt response to anakinra, a soluble IL1 receptor antagonist (sIL-1RA). In addition, we detected neutrophil epitheliotropism, which is highly suggestive of autoinflammatory disease. Using whole-exome sequencing, we were unable to find a causative pathogenic mutation but did find several mutations possibly related to the inflammatory processes in this patient. This and other cases highlight that the existing Strasbourg criteria are too strict to capture Schnitzler-like syndromes that may respond well and rapidly to IL1 inhibition. Recurrent episodes of disease with normalization of inflammatory symptoms in the interval, rapid response to anakinra, and neutrophilic epitheliotropism in a lesional skin biopsy may help confirm the diagnosis of Schnitzler-like syndrome.
Chronic constipation due to presacral teratoma in a 36-year-old woman: a case report
Authors: Daniel Paramythiotis, Theodossis S Papavramidis, Antonios Michalopoulos, Vassilios N Papadopoulos, Stylianos Apostolidis, Despoina Televantou, Prodromos Hytiroglou
Journal: J Med Case Rep (2010)

Introduction:
Teratomas of the sacrococcygeal area are usually diagnosed in infancy and are rarely seen in adults.
Case presentation:
We report the case of a 36-year-old Greek woman experiencing chronic constipation due to a benign presacral teratoma. Imaging examinations showed a pelvic mass without evidence of malignancy. An ovoid tumour with a maximum dimension of 6 cm was surgically removed. A histologic examination revealed a mature cystic teratoma. Two years after surgery, the patient is well, with no evidence of recurrence and no constipation.
Conclusion:
Sacrococcygeal teratomas are rare in adults. A high index of suspicion is important in making an early diagnosis. Rectal examination and radiologic evaluation are also valuable.
De Novo ring chromosome 11 and non-reciprocal translocation of 11p15.3-pter to 21qter in a patient with congenital heart disease
Authors: Ying Peng, Ruiyu Ma, Yingjie Zhou, Yan Xia, Juan Wen, Yanghui Zhang, Ruolan Guo, Haoxian Li, Qian Pan, Rui Zhang, Chengyuan Tang, Desheng Liang, Lingqian Wu
Journal: Mol Cytogenet (2015)
Keywords: 11q terminal deletions, congenital heart disease, non-reciprocal translocation, ring chromosome 11
MeSH terms: Case Reports

Background:
Ring chromosome 11[r (11)] is a rare chromosomal abnormality that forms when both arms of chromosome 11 break, and then reunite with each other. Once a ring chromosome forms, the distal ends of both arms of the chromosome are usually lost.
Case presentation:
We reported a 12 years old girl patient with congenital heart disease and distinctive facial features. Cytogenetic and molecular analyses using standard G-banding, fluorescence in situ hybridization and Single nucleotide polymorphism array were performed to identify genetic causes in the patient. The patient carried r(11)(p15.3q24.1) and 11p15.3-pter non-reciprocal translocation to 21qter, accompanied with 8.9 Mb deletion of 11q24.2q25. A literature review was performed to establish genotype-phenotype correlations of the r (11) and 11q terminal deletion syndrome.
Conclusions:
To the best of our knowledge, this is the first case of non-reciprocal translocation with a terminal deletion in r (11). These findings provide important information for genetic counseling for this family, and may improve our understanding of the genotype-phenotype correlation of ring chromosome 11 disorders.
Ceramic Laminate Veneers for Reestablishment of Esthetics in Case of Lateral Incisor Agenesis
Authors: Geórgia Silva, Ana Cristina Normandes, Edson Barros Júnior, Joyce Gatti, Kalena Maranhão, Ana Cássia Reis, Fernanda Jassé, Lucas Moura, Thaís Barros
Journal: Case Rep Dent (2018)
MeSH terms: Case Reports

The increasing demand of patients looking for esthetics has resulted in the development of several techniques to restore anterior teeth. Conservative treatments should always be the first therapeutic option for the solution of aesthetic problems involving morphological changes and usually provide the result that the patient expects. In this context, ceramic laminate veneers, also known as "contact lenses," are capable to provide an extremely faithful reproduction of natural teeth with great color stability and periodontal biocompatibility. Minimal or no preparation veneers are heavily advertised as the answer to patients' cosmetic needs, when properly indicated by the dentist. This paper reports a clinical case where lateral incisor agenesis was aesthetically corrected using ceramic laminates.
Case report: Vesiculobullous eruption with an atypical IgA deposition pattern in a patient with multiple myeloma-A case report and literature review
Authors: Tong Li, Hongjie Liu, Wei Li
Journal: Front Immunol (2023)
Keywords: iga autoantibodies, autoimmune bullous disease, direct immunofluorescence, monoclonal gammopathy, multiple myeloma
MeSH terms: Autoimmune Diseases, Multiple Myeloma / diagnosis, Skin Diseases, Vesiculobullous / diagnosis, Review, Case Reports, Autoantibodies, Blister, Humans, Immunoglobulin A, Autoantibodies, Immunoglobulin A

Cutaneous vesiculobullous eruptions associated with multiple myeloma (MM) are rare. Although the development of blisters is mostly driven by amyloid deposits of paraproteins in the skin, autoimmunity may play a role. In this study, we report an unusual case of an MM patient with blisters who presented with both flaccid and tense vesicles and bullae. Direct immunofluorescence revealed IgA autoantibody deposits in the basement membrane zone (BMZ) and intercellular space of the epidermis, which displayed an atypical autoantibody deposition pattern. The patient showed rapid disease progression and died during follow-up. We performed a literature review of autoimmune bullous diseases (AIBDs) associated with MM or its precursors and found 17 previously reported cases. Together with the present case, cutaneous involvement of the skin folds was frequently reported, and mucous membranes were barely affected. IgA pemphigus, with consistent IgA monoclonality, was observed in half of the cases. Five patients displayed atypical autoantibody deposition patterns in the skin; the prognosis of these patients appeared to be poorer than that of other patients. We aim to increase our understanding of AIBDs associated with MM or its precursors.
Internal Limiting Membrane Peeling for Persistent Submacular Fluid after Successful Repair of Diabetic Tractional Retinal Detachment
Authors: Byung Ju Jung, Sohee Jeon, Kook Lee, Jiwon Baek, Won Ki Lee
Journal: J Ophthalmol (2019)

This study is for reporting the outcomes of internal limiting membrane (ILM) peeling on persistent submacular fluid (PSF) after otherwise successful pars plana vitrectomy (PPV) for diabetic tractional retinal detachment (TRD). In this retrospective case series, five consecutive patients (5 eyes) who exhibited PSF following successful repair of diabetic TRD were included. The second operation was performed to remove ILM. The area of ILM peeling was expanded up to the major vascular arcade. Only air tamponade was used. The median interval between the first PPV and the second PPV with ILM peeling was 4.8 months (range: 4-6 months). PSF resolved completely within one (2 eyes) or 2 months after ILM peeling. The median logMAR best-corrected visual acuity (BCVA) was improved from 1.00 (Snellen equivalent 20/200) to 0.70 (Snellen equivalent 20/100). In conclusion, wide ILM peeling is an effective treatment option for PSF subsequent to successful repair of diabetic TRD. ILM peeling might increase the elasticity of retina, thereby allowing the retina to flatten. This procedure can induce faster retinal reattachment in diabetic TRD involving the macula.
Oestrus ovis L. (Diptera: Oestridae) Induced Nasal Myiasis in a Dog from Northern Italy
Authors: Sergio A Zanzani, Luigi Cozzi, Emanuela Olivieri, Alessia L Gazzonis, Maria Teresa Manfredi
Journal: Case Rep Vet Med (2016)
MeSH terms: Case Reports

A companion dog from Milan province (northern Italy), presenting with frequent and violent sneezing, underwent rhinoscopy, laryngoscopy, and tracheoscopy procedures. During rhinoscopy, a dipteran larva was isolated from the dog and identified as first instar larval stage of O. ovis by morphological features. Reports of O. ovis in domestic carnivores are sporadic and nevertheless this infestion should be considered as a possible differential diagnosis of rhinitis in domestic carnivores living in contaminated areas by the fly as consequence of the presence of sheep and goats. This report described a case of autochthonous infestion in a dog from an area where O. ovis was not historically present but it could be affected by a possible expansion of the fly as a consequence of climate change. This is the first record of Oestrus ovis infestion in a dog in Italy and, at the same time, the most northerly finding of larvae of sheep bot fly in the country.
The presence of precursors of benign pre-B lymphoblasts (hematogones) in the bone marrow of a paediatric patient with cytomegalovirus infection
Authors: F Moreno-Madrid, J Uberos, M Díaz-Molina, A Ramírez-Arredondo, P Jiménez-Gámiz, A Molina-Carballo
Journal: Clin Med Oncol (2008)
Keywords: acute lymphoblastic leukemia, cytomegalovirus, hematogones, infants, leukemia, pre-b cells
MeSH terms: Case Reports

Hematogones are normal B-lymphoid precursors that multiply in the bone marrow of small children and of adults with ferropenic anaemia, neuroblastoma or idiopathic thrombocytopenic purpura. They are not normally found in peripheral blood, and the immunophenotype is virtually indistinguishable from that of B lymphoblasts. We discuss the case of a 3-month infant with an active cytomegalovirus infection, with hepatitis and pancytopenia associated with 13% hematogones in the bone marrow.
Leishmania life cycle images in the cutaneous cytologic smear of an immunocompetent patient
Authors: Roberta Zappacosta, Roberta Claudi, Salvatore Magnasco, Emma Dell'osa
Journal: J Cytol (2010)
Keywords: cutaneous leishmaniasis, leishmania, scrape cytology, sporadic leishmaniasis
MeSH terms: Case Reports

Cutaneous leishmania life cycle images on cytology smears are very rare. We report herein a gallery of cytologic images from a case of sporadic cutaneous leishmaniasis in a 61 year old man presenting with ulcerative skin lesion.
Myotonic Dystrophy and Anesthetic Challenges: A Case Report and Review
Authors: Chanchal Mangla, Kimmy Bais, Joel Yarmush
Journal: Case Rep Anesthesiol (2019)
MeSH terms: Case Reports

Providing anesthesia to patients with myotonic dystrophy (DM) can be very challenging due to the multisystemic effects of the disease and extreme sensitivity of these patients to sedatives, opioids, and anesthetic agents. Other factors such as hypothermia, shivering, or mechanical or electric stimulation during surgery can precipitate myotonia which is difficult to abolish and can lead to further complications. Generally, local or regional anesthesia is preferred to avoid the complications associated with general anesthesia in this group. However there are several case reports of successful use of general anesthesia (with or without volatile agents and with or without opioids). These general anesthetic cases led to postoperative admission to the regular floor or ICU. We present a case of a woman with a history of DM who underwent robotic assisted laparoscopic hysterectomy under general anesthesia and was discharged home on the same day.