# Lijst van nummer 1-hits in de UK Singles Chart in 1981

Deze hits stonden in 1981 op nummer 1 in de UK Singles Chart:
| Datum | Artiest | Titel |
| 3 januari | St Winifred's School Choir | There's no one quite like grandma |
| 10 januari | John Lennon | Imagine |
| 17 januari | John Lennon | Imagine |
| 24 januari | John Lennon | Imagine |
| 31 januari | John Lennon | Imagine |
| 7 februari | John Lennon | Woman |
| 14 februari | John Lennon | Woman |
| 21 februari | Joe Dolce Music Theatre | Shaddap you face |
| 28 februari | Joe Dolce Music Theatre | Shaddap you face |
| 7 maart | Joe Dolce Music Theatre | Shaddap you face |
| 14 maart | Roxy Music | Jealous guy |
| 21 maart | Roxy Music | Jealous guy |
| 28 maart | Shakin' Stevens | This ole house |
| 4 april | Shakin' Stevens | This ole house |
| 11 april | Shakin' Stevens | This ole house |
| 18 april | Bucks Fizz | Making your mind up |
| 25 april | Bucks Fizz | Making your mind up |
| 2 mei | Bucks Fizz | Making your mind up |
| 9 mei | Adam & the Ants | Stand and deliver |
| 16 mei | Adam & the Ants | Stand and deliver |
| 23 mei | Adam & the Ants | Stand and deliver |
| 30 mei | Adam & the Ants | Stand and deliver |
| 6 juni | Adam & the Ants | Stand and deliver |
| 13 juni | Smokey Robinson | Being with you |
| 20 juni | Smokey Robinson | Being with you |
| 27 juni | Michael Jackson | One day in your life |
| 4 juli | Michael Jackson | One day in your life |
| 11 juli | The Specials | Ghosttown |
| 18 juli | The Specials | Ghosttown |
| 25 juli | The Specials | Ghosttown |
| 1 augustus | Shakin' Stevens | Green door |
| 8 augustus | Shakin' Stevens | Green door |
| 15 augustus | Shakin' Stevens | Green door |
| 22 augustus | Shakin' Stevens | Green door |
| 29 augustus | Aneka | Japanese boy |
| 5 september | Soft Cell | Tainted love |
| 12 september | Soft Cell | Tainted love |
| 19 september | Adam & the Ants | Prince Charming |
| 26 september | Adam & the Ants | Prince Charming |
| 3 oktober | Adam & the Ants | Prince Charming |
| 10 oktober | Adam & the Ants | Prince Charming |
| 17 oktober | Dave Stewart & Barbara Gaskin | It's my party |
| 24 oktober | Dave Stewart & Barbara Gaskin | It's my party |
| 31 oktober | Dave Stewart & Barbara Gaskin | It's my party |
| 7 november | Dave Stewart & Barbara Gaskin | It's my party |
| 14 november | The Police | Every little thing she does is magic |
| 21 november | Queen & David Bowie | Under pressure |
| 28 november | Queen & David Bowie | Under pressure |
| 5 december | Julio Iglesias | Begin the beguine (Volver a empezar) |
| 12 december | Human League | Don't you want me |
| 19 december | Human League | Don't you want me |
| 26 december | Human League | Don't you want me |
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