# Genetics/Human Leukocyte Antigen/Linkage Disequilibrium/DR-DQ Blocks

(Block frequency is expressed as the negative of the decimal logarithm of the frequency, that is 1 is 1 in 10, 2 is 1 in 100, 3 is 1 in 1000, etc.)
| DRB1 | DRB345 | DQA1 | DQB1 | NegLogFreq | Notes |
| DRB1*01:01:01 | - | DQA1*01:01:01 | DQB1*05:01:01:01 | 1.1 | |
| DRB1*01:01:01 | - | DQA1*01:02:01:01 | DQB1*05:04 | 3 | |
| DRB1*01:02:01 | - | DQA1*01:01:01 | DQB1*05:01:01:01 | 1.7 | |
| DRB1*01:03 | - | DQA1*01:01:01 | DQB1*05:01:01:01 | 1.9 | |
| DRB1*01:03 | - | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 3 | |
| DRB1*03:01:01:01 | DRB3*01:01:02:01 | DQA1*05:01:01 | DQB1*02:01:01 | 1.1 | Associated with B8 |
| DRB1*03:01:01:01 | DRB3*02:02:01:01 | DQA1*05:01:01 | DQB1*02:01:01 | 1.7 | Not associated with B8 |
| DRB1*03:01:01:01 | DRB3*01:01:02:01 | DQA1*01:02:01:01 | DQB1*06:02:01 | 3.2 | |
| DRB1*03:01:01:01 | DRB3*01:01:02:01 | DQA1*05:01:01 | DQB1*03:01:01:01 | 3.5 | |
| DRB1*03:01:01:01 | DRB3*02:01 | DQA1*05:01:01 | DQB1*02:01:01 | 3.5 | Jewish (Rumania) |
| DRB1*03:02:01 | DRB3*01:01:02:01 | DQA1*04:01:01 | DQB1*04:02 | 2.5 | African |
| DRB1*03:02:01 | DRB3*03:01:01 | DQA1*04:01:01 | DQB1*04:02 | 3.5 | African |
| DRB1*04:01:01 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*03:01:01:01 | 1.4 | Associated with B*4402 |
| DRB1*04:01:01 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:02:01 | 1.4 | Associated with B*1501 |
| DRB1*04:01:01 | DRB4*01:03:01:02N | DQA1*03:01:01 | DQB1*03:02:01 | 3 | |
| DRB1*04:01:01 | DRB4*01:02 | DQA1*03:03 | DQB1*03:01:01:01 | 3.5 | |
| DRB1*04:02:01 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:02:01 | 2 | More in Jewish & Arab. Associated with B*3801. |
| DRB1*04:02:01 | DRB4*01:03:01:02N | DQA1*03:01:01 | DQB1*03:02:01 | 3.5 | More in Jewish & Arab. |
| DRB1*04:03:01 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:02:01 | 1.9 | |
| DRB1*04:03:01 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:04 | 2.8 | Sardinians |
| DRB1*04:03:01 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:05:01 | 2.8 | Eastern Europe and Jewish. |
| DRB1*04:04:01 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:02:01 | 1.4 | |
| DRB1*04:05:01 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*03:02:01 | 2.1 | Mediterranean & African |
| DRB1*04:05:01 | DRB4*01:03:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 3 | Sardinians |
| DRB1*04:05:01 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*02:02 | 3 | African & Jewish |
| DRB1*04:05:01 | DRB4*01:03:01:01 | DQA1*01:03:01:01 | DQB1*05:03:01:01 | 3.5 | Filipino |
| DRB1*04:05:01 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*04:01:01 | 3.5 | |
| DRB1*04:06:01 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:02:01 | 3.2 | Asian |
| DRB1*04:06:01 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*04:02 | 4 | African |
| DRB1*04:07:01 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:02:01 | 1.9 | Native American |
| DRB1*04:07:01 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*03:01:01:01 | 1.9 | Caucasian & African |
| DRB1*04:08:01 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*03:01:01:01 | 2.5 | |
| DRB1*04:08:01 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*03:04 | 2.9 | Czech |
| DRB1*04:09 | DRB4*01:03:01:01 | DQA1*03:03 | DQB1*03:01:01:01 | 4 | |
| DRB1*04:10 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*04:02 | 3.5 | Asian |
| DRB1*04:10 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:02:01 | 4 | |
| DRB1*04:11 | DRB4*01:03:01:01 | DQA1*03:01:01 | DQB1*03:02:01 | 2.6 | Asian & Native American |
| DRB1*07:01:01:01 | DRB4*01:01:01:01 | DQA1*02:01 | DQB1*02:02 | 1.2 | |
| DRB1*07:01:01:01 | DRB4*01:03:01:01 | DQA1*02:01 | DQB1*02:02 | 1.4 | |
| DRB1*07:01:01:01 | DRB4*01:03:01:02N | DQA1*02:01 | DQB1*02:02 | 3.5 | |
| DRB1*07:01:01:01 | DRB4*01:03:01:01 | DQA1*02:01 | DQB1*03:02:01 | 3.5 | |
| DRB1*08:01:01 | - | DQA1*04:01:01 | DQB1*04:02 | 1.9 | Caucasian |
| DRB1*08:01:01 | DRB3*02:02:01:01 | DQA1*04:01:01 | DQB1*04:02 | 3.5 | |
| DRB1*08:02:01 | - | DQA1*04:01:01 | DQB1*04:02 | 2.3 | Asian & Native American |
| DRB1*08:03:02 | - | DQA1*06:01:01 | DQB1*03:01:01:01 | 3.2 | Europe. Peculiar DQ block found in Europe with DRB1*080302 and in Asia with DRB1*120201 – DRB3*030101. |
| DRB1*08:03:02 | - | DQA1*04:01:01 | DQB1*06:01:01 | 3.5 | Asian |
| DRB1*08:04:01 | - | DQA1*05:05:01:01 | DQB1*03:19 | | African. DQA1*0505 needs confirmation, possibly it comes form the block DRB1*110201 - DRB3*0202 - DQA1*0505 - DQB1*0319. |
| DRB1*08:04:01 | - | DQA1*04:01:01 | DQB1*03:01:01:01 | 2.6 | African |
| DRB1*08:04:01 | - | DQA1*04:01:01 | DQB1*04:02 | 3.2 | Africa, Europe. Relatively to all DRB1*080401, this block is more common in Europe than in Africa. In Europe with B*5801 - Cw*0718. In Africa with B*8101 - Cw*1801. Associated with A*290201, regardless of the BC block. |
| DRB1*08:04:04 | - | DQA1*04:01:01 | DQB1*04:02 | | Mexican. With B*4002 - Cw*0306. |
| DRB1*08:06 | - | DQA1*01:02:01:01 | DQB1*06:02:01 | 2.9 | African |
| DRB1*08:07 | - | DQA1*04:01:01 | DQB1*04:02 | 3 | South American Indian |
| DRB1*08:11 | - | DQA1*04:01:01 | DQB1*04:02 | 3.5 | Pacific North West Indians & Eskimos |
| DRB1*09:01:02 | DRB4*01:03:01:01 | DQA1*03:02 | DQB1*03:03:02:01 | 2.1 | Caucasian, Asian, North American Indians |
| DRB1*09:01:02 | DRB4*01:01:01:01 | DQA1*03:02 | DQB1*02:02 | 2.7 | African |
| DRB1*10:01:01 | - | DQA1*01:04:01:01 | DQB1*05:01:01:01 | 2 | |
| DRB1*11:01:01 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 1.3 | |
| DRB1*11:01:01 | DRB3*01:01:02:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 3.2 | |
| DRB1*11:01:01 | DRB3*02:02:01:01 | DQA1*01:02:01:01 | DQB1*05:01:01:01 | 3.5 | Hispanic |
| DRB1*11:01:01 | DRB3*02:02:01:01 | DQA1*01:02:01:01 | DQB1*06:03:01 | 4 | |
| DRB1*11:01:02 | DRB3*02:02:01:01 | DQA1*01:02:01:01 | DQB1*06:02:01 | 3 | African |
| DRB1*11:01:02 | DRB3*03:01:01 | DQA1*01:02:01:01 | DQB1*05:02:01 | 3.5 | |
| DRB1*11:02:01 | DRB3*02:10 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 4 | |
| DRB1*11:02:01 | DRB3*03:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 4 | African |
| DRB1*11:03 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 2.4 | |
| DRB1*11:04:01 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 1.5 | Jewish and other populations |
| DRB1*11:04:01 | DRB3*02:02:01:01 | DQA1*01:03:01:01 | DQB1*06:03:01 | 3 | Exclusively Jewish |
| DRB1*11:04:01 | DRB3*02:02:01:01 | DQA1*01:02:01:01 | DQB1*06:02:01 | 3.5 | |
| DRB1*11:12:01 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 4 | |
| DRB1*11:14:01 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 4 | |
| DRB1*11:15 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 3.5 | |
| DRB1*11:42 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 3.5 | |
| DRB1*12:01:01 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 2.2 | Caucasian & Asian |
| DRB1*12:01:01 | DRB3*01:01:02:01 | DQA1*01:04:01:01 | DQB1*05:01:01:01 | 3 | African |
| DRB1*12:01:01 | DRB3*01:01:02:01 | DQA1*03:02 | DQB1*03:03:02:01 | 3.5 | African?, Asian |
| DRB1*12:01:01 | DRB3*02:02:01:01 | DQA1*01:04:01:01 | DQB1*05:01:01:01 | 4 | African |
| DRB1*12:02:01 | DRB3*03:01:01 | DQA1*06:01:01 | DQB1*03:01:01:01 | 2.8 | Asia. Peculiar DQ block found in Europe with DRB1*080302 and in Asia with DRB1*120201 – DRB3*030101. |
| DRB1*13:01:01 | DRB3*01:01:02:01 | DQA1*01:03:01:01 | DQB1*06:03:01 | 1.5 | |
| DRB1*13:01:01 | DRB3*02:02:01:01 | DQA1*01:03:01:01 | DQB1*06:03:01 | 1.7 | |
| DRB1*13:01:01 | DRB3*03:01:01 | DQA1*01:02:01:01 | DQB1*05:01:01:01 | 3.2 | |
| DRB1*13:01:01 | DRB3*01:01:02:01 | DQA1*01:02:01:01 | DQB1*05:01:01:01 | 3.5 | |
| DRB1*13:01:01 | DRB3*03:01:01 | DQA1*01:02:01:01 | DQB1*06:09 | 3.5 | |
| DRB1*13:01:01 | DRB3*01:01:02:01 | DQA1*01:03:01:01 | DQB1*06:02:01 | 3.5 | |
| DRB1*13:01:01 | DRB3*01:01:02:01 | DQA1*03:02 | DQB1*03:03:02:01 | 3.5 | |
| DRB1*13:01:01 | DRB3*03:01:01 | DQA1*01:02:01:01 | DQB1*06:04:01 | 3.5 | |
| DRB1*13:02:01 | DRB3*03:01:01 | DQA1*01:02:01:01 | DQB1*06:04:01 | 1.5 | |
| DRB1*13:02:01 | DRB3*03:01:01 | DQA1*01:02:01:01 | DQB1*06:09 | 2.1 | |
| DRB1*13:02:01 | DRB3*03:01:01 | DQA1*01:02:01:01 | DQB1*05:01:01:01 | 3 | |
| DRB1*13:02:01 | DRB3*02:02:01:01 | DQA1*01:02:01:01 | DQB1*06:04:01 | 3.5 | |
| DRB1*13:03:01 | DRB3*01:01:02:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 2 | |
| DRB1*13:03:01 | DRB3*02:02:01:01 | DQA1*02:01 | DQB1*02:02 | 3.5 | African |
| DRB1*13:04 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:19 | 3.5 | African |
| DRB1*13:05:01 | DRB3*02:02:01:01 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 2.6 | Jewish |
| DRB1*14:01:01 | DRB3*02:01 | DQA1*01:04:01:01 | DQB1*05:03:01:01 | 3.2 | Jewish |
| DRB1*14:02 | DRB3*01:01:02:01 | DQA1*05:03 | DQB1*03:01:01:01 | 2.6 | Native American & Asian |
| DRB1*14:02 | DRB3*01:01:02:01 | DQA1*05:03 | DQB1*03:04 | 3.5 | |
| DRB1*14:02 | DRB3*02:02:01:01 | DQA1*05:03 | DQB1*03:01:01:01 | 3.5 | |
| DRB1*14:04 | DRB3*02:02:01:01 | DQA1*01:04:01:01 | DQB1*05:03:01:01 | 4 | Indian |
| DRB1*14:05:01 | DRB3*02:02:01:01 | DQA1*01:04:01:01 | DQB1*05:03:01:01 | 4 | Oriental |
| DRB1*14:06:01 | DRB3*01:01:02:01 | DQA1*05:03 | DQB1*03:01:01:01 | 2.3 | Native American |
| DRB1*14:07:01 | DRB3*02:02:01:01 | DQA1*01:04:01:01 | DQB1*05:03:01:01 | 3.5 | |
| DRB1*14:17 | DRB3*01:01:02:01 | DQA1*01:02:01:01 | DQB1*06:04:01 | 3.5 | |
| DRB1*14:21 | DRB3*01:01:02:01 | DQA1*01:03:01:01 | DQB1*06:03:01 | 3.5 | |
| DRB1*14:54 | DRB3*02:02:01:01 | DQA1*01:04:01:01 | DQB1*05:03:01:01 | 1.6 | Universal |
| DRB1*14:54 | DRB3*02:02:01:01 | DQA1*01:04:01:01 | DQB1*05:02:01 | 3.2 | Asian |
| DRB1*14:54 | DRB3*02:02:01:01 | DQA1*01:04:01:01 | DQB1*06:02:01 | 3.5 | |
| DRB1*14:54 | DRB3*02:02:01:01 | DQA1*01:04:01:01 | DQB1*05:01:01:01 | 3.5 | |
| DRB1*14:54 | DRB3*02:03 | DQA1*01:04:01:01 | DQB1*05:03:01:01 | 4 | |
| DRB1*15:01:01:01 | DRB5*01:01:01 | DQA1*01:02:01:01 | DQB1*06:02:01 | 1 | |
| DRB1*15:01:01:01 | DRB5*01:01:01 | DQA1*01:02:01:01 | DQB1*06:03:01 | 2.3 | |
| DRB1*15:01:01:01 | DRB5*01:01:01 | DQA1*01:02:01:01 | DQB1*05:02:01 | 2.8 | |
| DRB1*15:01:01:01 | DRB5*01:01:01 | DQA1*01:02:01:01 | DQB1*06:04:01 | 3.5 | |
| DRB1*15:01:01:01 | - | DQA1*01:02:01:01 | DQB1*06:02:01 | 3.5 | B6763 |
| DRB1*15:01:01:01 | DRB5*01:01:02 | DQA1*01:02:01:01 | DQB1*06:02:01 | 4 | |
| DRB1*15:02:01 | DRB5*01:02 | DQA1*01:03:01:01 | DQB1*06:01:01 | 2.2 | |
| DRB1*15:03:01:01 | DRB5*01:01:01 | DQA1*01:02:01:01 | DQB1*06:02:01 | 2.2 | African |
| DRB1*15:03:01:01 | DRB5*01:01:01 | DQA1*03:02 | DQB1*06:03:01 | 3.5 | |
| DRB1*15:03:01:01 | DRB5*01:01:01 | DQA1*03:02 | DQB1*02:02 | 3.5 | |
| DRB1*15:03:01:01 | - | DQA1*01:02:01:01 | DQB1*06:02:01 | 3.5 | |
| DRB1*16:01:01 | DRB5*02:02 | DQA1*01:02:01:01 | DQB1*05:02:01 | 1.9 | Caucasian |
| DRB1*16:01:01 | DRB5*01:01:01 | DQA1*01:02:01:01 | DQB1*05:02:01 | 4 | Caucasian |
| DRB1*16:02:01 | DRB5*01:01:01 | DQA1*01:02:01:01 | DQB1*05:02:01 | | SE Asia |
| DRB1*16:02:01 | DRB5*02:02 | DQA1*01:02:01:01 | DQB1*05:02:01 | 2.6 | African, Asian |
| DRB1*16:02:01 | DRB5*02:02 | DQA1*05:05:01:01 | DQB1*03:01:01:01 | 2.6 | American |
| DRB1*16:02:01 | DRB5*02:03 | DQA1*01:02:01:01 | DQB1*05:02:01 | 3.5 | Asian |
| DRB1*16:05:01 | DRB5*02:02 | DQA1*01:02:01:01 | DQB1*05:02:01 | 3.5 | |