# ICD-10-CM (2010)/CHAPTER 18

​=Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)=
    This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
    Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated "not otherwise specified", "unknown etiology" or "transient". The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
    The conditions and signs or symptoms included in categories R00-R94 consist of: (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated: (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined; (c) provisional diagnosis in a patient who failed to return for further investigation or care;(d) cases referred elsewhere for investigation or treatment before the diagnosis was made; (e) cases in which a more precise diagnosis was not available for any other reason; (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
    Excludes2: abnormal findings on antenatal screening of mother (O28.-)
       certain conditions originating in the perinatal period (P04-P96)
       signs and symptoms classified in the body system chapters
       signs and symptoms of breast (N63, N64.5)
    This chapter contains the following blocks:
    R00-R09 Symptoms and signs involving the circulatory and respiratory systems
    R10-R19 Symptoms and signs involving the digestive system and abdomen
    R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
    R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
    R30-R39 Symptoms and signs involving the urinary system
    R40-R46 Symptoms and signs involving cognition, perception, emotional state and behavior
    R47-R49 Symptoms and signs involving speech and voice
    R50​R69 General symptoms and signs
    R70-R79 Abnormal findings on examination of blood, without diagnosis
    R80-R82 Abnormal findings on examination of urine, without diagnosis
    R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
    R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
    R97 Abnormal tumor markers
    R99 Ill-defined and unknown cause of mortality

# Symptoms and signs involving the circulatory and respiratory systems (R00-R09)Symptoms and signs involving the circulatory and respiratory systems (R00-R09)
## R00 Abnormalities of heart beatR00 Abnormalities of heart beat

    Excludes1: abnormalities originating in the perinatal period (P29.1)
       specified arrhythmias (I47-I49)
    R00.0 Tachycardia, unspecified
       Rapid heart beat
       Sinoauricular tachycardia NOS
       Sinus [sinusal] tachycardia NOS
       Excludes1: neonatal tachycardia (P29.11)
          paroxysmal tachycardia (I47.-)
    R00.1 Bradycardia, unspecified
       Sinoatrial bradycardia
       Sinus bradycardia
       Slow heart beat
       Vagal bradycardia
       Excludes1: neonatal bradycardia (P29.12)
    R00.2 Palpitations
       Awareness of heart beat
    R00.8 Other abnormalities of heart beat
    R00.9 Unspecified abnormalities of heart beat

## R01 Cardiac murmurs and other cardiac soundsR01 Cardiac murmurs and other cardiac sounds

    Excludes1: cardiac murmurs and sounds originating in the perinatal period (P29.8)
    R01.0 Benign and innocent cardiac murmurs
       Functional cardiac murmur
    R01.1 Cardiac murmur, unspecified
       Cardiac bruit NOS
       Heart murmur NOS
    R01.2 Other cardiac sounds
       Cardiac dullness, increased or decreased
       Precordial friction

## R03 Abnormal blood-pressure reading, without diagnosisR03 Abnormal blood-pressure reading, without diagnosis

    R03. ​0 Elevated blood-pressure reading, without diagnosis of hypertension
    Note: This category is to be used to record an episode of elevated blood pressure in a patient in whom no formal diagnosis of hypertension has been made, or as an isolated incidental finding.
    R03.1 Nonspecific low blood-pressure reading
       Excludes1: hypotension (I95.-)
          maternal hypotension syndrome (O26.5-)
          neurogenic orthostatic hypotension (G90.3)

## R04 Hemorrhage from respiratory passagesR04 Hemorrhage from respiratory passages

    R04.0 Epistaxis
       Hemorrhage from nose
       Nosebleed
    R04.1 Hemorrhage from throat
       Excludes2: hemoptysis (R04.2)
    R04.2 Hemoptysis
       Blood-stained sputum
       Cough with hemorrhage
    R04.8 Hemorrhage from other sites in respiratory passages
       Pulmonary hemorrhage NOS
       Excludes1: perinatal pulmonary hemorrhage (P26.-)
    R04.9 Hemorrhage from respiratory passages, unspecified

## R05 CoughR05 Cough

    Excludes1: cough with hemorrhage (R04.2)
       smoker's cough (J41.0)

## R06 Abnormalities of breathingR06 Abnormalities of breathing

    Excludes1: acute respiratory distress syndrome (J80)
       respiratory arrest (R09.2)
       respiratory arrest of newborn (P28.81)
       respiratory distress syndrome of newborn (P22.-)
       respiratory failure (J96.-)
       respiratory failure of newborn (P28.5)
    R06.0 Dyspnea
       Excludes1: tachypnea NOS (R06.82)
          transient tachypnea of newborn (P22.1)
       R06.00 Dyspnea NOS
       R06.01 Orthopnea
       R06.02 Shortness of breath
       R06.09 Other forms of dyspnea
    R06.1 Stridor
       Excludes1: congenital laryngeal stridor (P28.89)
          laryngismus (stridulus) (J38.5)
    R06.2 Wheezing
       Excludes1: Asthma (J45.-)
    R06. ​3 Periodic breathing
       Cheyne-Stokes breathing
    R06.4 Hyperventilation
       Excludes1: psychogenic hyperventilation (F45.8)
    R06.5 Mouth breathing
       Excludes2: dry mouth NOS (R68.2)
    R06.6 Hiccough
       Excludes1: psychogenic hiccough (F45.8)
    R06.7 Sneezing
    R06.8 Other abnormalities of breathing
       R06.81 Apnea, not elsewhere classified
          Apnea NOS
          Excludes1: apnea (of) newborn (P28.4)
             sleep apnea (G47.3-)
             sleep apnea of newborn (primary) (P28.3)
       R06.82 Tachypnea, not elsewhere classified
          Tachypnea NOS
          Excludes1: transitory tachypnea of newborn (P22.1)
       R06.83 Snoring
       R06.89 Other abnormalities of breathing
          Breath-holding (spells)
          Sighing
    R06.9 Unspecified abnormalities of breathing

## R07 Pain in throat and chestR07 Pain in throat and chest

    Excludes1: epidemic myalgia (B33.0)
    Excludes2: pain in breast (N64.4)
    R07.0 Pain in throat
       Excludes1: chronic sore throat (J31.2)
          sore throat (acute) NOS (J02.9)
       Excludes2: dysphagia (R13.1-)
          pain in neck (M54.2)
    R07.1 Chest pain on breathing
       Painful respiration
    R07.2 Precordial pain
    R07.8 Other chest pain
       R07.81 Pleurodynia
          Pleurodynia NOS
          Excludes1: epidemic pleurodynia (B33.0)
       R07.82 Intercostal pain
       R07.89 Other chest pain
          Anterior chest-wall pain NOS
    R07.9 Chest pain, unspecified

## R09 Other symptoms and signs involving the circulatory and respiratory systemR09 Other symptoms and signs involving the circulatory and respiratory system

    Excludes1: acute respiratory distress syndrome (J80)
       respiratory ​arrest of newborn (P28.81)
       respiratory distress syndrome of newborn (P22.0)
       respiratory failure (J96.-)
       respiratory failure of newborn (P28.5)
    R09.0 Asphyxia and hypoxemia
       Excludes1: asphyxia due to carbon monoxide (T58.-)
          asphyxia due to foreign body in respiratory tract (T17.-)
          birth (intrauterine) asphyxia (P84)
          hypercapnia (R06.4)
          hyperventilation (R06.4)
          traumatic asphyxia (T71-)
       R09.01 Asphyxia
       R09.02 Hypoxemia
    R09.1 Pleurisy
       Excludes1: pleurisy with effusion (J90)
    R09.2 Respiratory arrest
       Cardiorespiratory failure
       Excludes1: cardiac arrest (I46.-)
          respiratory arrest of newborn (P28.81)
          respiratory distress of newborn (P22.0)
          respiratory failure (J96.-)
          respiratory failure of newborn (P28.5)
          respiratory insufficiency (R06.89)
          respiratory insufficiency of newborn (P28.5)
    R09.3 Abnormal sputum
       Abnormal amount of sputum
       Abnormal color of sputum
       Abnormal odor of sputum
       Excessive sputum
       Excludes1: blood-stained sputum (R04.2)
    R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
       R09.81 Nasal congestion
       R09.82 Postnasal drip
       R09.89 Other specified symptoms and signs involving the circulatory and respiratory systems
          Bruit (arterial)
          Abnormal chest percussion
          Feeling of foreign body in throat
          Friction sounds in chest
          Chest tympany
          Choking sensation
          Rales
          Weak pulse
          Excludes2: foreign body in throat (T17.2-)
             wheezing (R06.2)

# Symptoms ​and signs involving the digestive system and abdomen (R10-R19)

    Excludes1: congenital or infantile pylorospasm (Q40.0)
       gastrointestinal hemorrhage (K92.0-K92.2)
       intestinal obstruction (K56.-)
       newborn gastrointestinal hemorrhage (P54.0-P54.3)
       newborn intestinal obstruction (P76.-)
       pylorospasm (K31.3)
       signs and symptoms involving the urinary system (R30-R39)
       symptoms referable to female genital organs (N94.-)
       symptoms referable to male genital organs male (N48-N50)

## R10 Abdominal and pelvic painR10 Abdominal and pelvic pain

    Excludes1: renal colic (N23)
    Excludes2: dorsalgia (M54.-)
       flatulence and related conditions (R14.-)
    R10.0 Acute abdomen
       Severe abdominal pain (generalized) (with abdominal rigidity)
       Excludes1: abdominal rigidity NOS (R19.3)
          generalized abdominal pain NOS (R10.84)
          localized abdominal pain (R10.1-R10.3-)
    R10.1 Pain localized to upper abdomen
       R10.10 Upper abdominal pain, unspecified
       R10.11 Right upper quadrant pain
       R10.12 Left upper quadrant pain
       R10.13 Epigastric pain
    R10.2 Pelvic and perineal pain
       Excludes1: vulvodynia (N94.81)
    R10.3 Pain localized to other parts of lower abdomen
       R10.30 Lower abdominal pain, unspecified
       R10.31 Right lower quadrant pain
       R10.32 Left lower quadrant pain
       R10.33 Periumbilical pain
    R10.8 Other abdominal pain
       R10.81 Abdominal tenderness
          Abdominal tenderness NOS
          R10.811 Right upper quadrant abdominal tenderness
          R10.812 Left upper quadrant abdominal tenderness
          R10.813 Right lower quadrant abdominal tenderness
          R10.814 Left lower quadrant abdominal tenderness
          R10.815 Periumbilic abdominal tenderness
          R10.816 Epigastric abdominal tenderness
          R10.817 Generalized abdominal tenderness
          R10.819 Abdominal tenderness, unspecified site
       R10. ​82 Rebound abdominal tenderness
          R10.821 Right upper quadrant rebound abdominal tenderness
          R10.822 Left upper quadrant rebound abdominal tenderness
          R10.823 Right lower quadrant rebound abdominal tenderness
          R10.824 Left lower quadrant rebound abdominal tenderness
          R10.825 Periumbilic rebound abdominal tenderness
          R10.826 Epigastric rebound abdominal tenderness
          R10.827 Generalized rebound abdominal tenderness
          R10.829 Rebound abdominal tenderness, unspecified site
       R10.83 Colic
          Colic NOS
          Infantile colic
          Excludes1: colic in adult and child over 12 months old (R10.84)
       R10.84 Generalized abdominal pain
          Excludes1: generalized abdominal pain associated with acute abdomen (R10.0)
    R10.9 Unspecified abdominal pain

## R11 Nausea and vomitingR11 Nausea and vomiting

    Excludes1: cyclical vomiting associated with migraine (G43.a-)
       excessive vomiting in pregnancy (O21.-)
       hematemesis (K92.0)
       neonatal hematemesis (P54.0)
       newborn vomiting (P92.0-)
       psychogenic vomiting (F50.8)
       vomiting associated with bulimia nervosa (F50.2)
       vomiting following gastrointestinal surgery (K91.0)
    R11.0 Nausea
       Nausea NOS
       Nausea without vomiting
    R11.1 Vomiting
       R11.10 Vomiting, unspecified
          Vomiting NOS
       R11.11 Vomiting without nausea
       R11.12 Projectile vomiting
       R11.13 Vomiting of fecal matter
       R11.14 Bilious vomiting
          Bilious emesis
    R11.2 Nausea with vomiting, unspecified
       Persistent nausea with vomiting NOS

## R12 HeartburnR12 Heartburn

    Excludes1: ​dyspepsia (K30)

## R13 Aphagia and dysphagiaR13 Aphagia and dysphagia

    R13.0 Aphagia
       Inability to swallow
       Excludes1: psychogenic aphagia (F50.9)
    R13.1 Dysphagia
       Code first, if applicable, dysphagia following cerebrovascular disease (I69. with final characters -91)
       Excludes1: psychogenic dysphagia (F45.8)
       R13.10 Dysphagia, unspecified
          Difficulty in swallowing NOS
       R13.11 Dysphagia, oral phase
       R13.12 Dysphagia, oropharyngeal phase
       R13.13 Dysphagia, pharyngeal phase
       R13.14 Dysphagia, pharyngoesophageal phase
       R13.19 Other dysphagia
          Cervical dysphagia
          Neurogenic dysphagia

## R14 Flatulence and related conditionsR14 Flatulence and related conditions

    Excludes1: psychogenic aerophagy (F45.8)
    R14.0 Abdominal distension (gaseous)
       Bloating
       Tympanites (abdominal) (intestinal)
    R14.1 Gas pain
    R14.2 Eructation
    R14.3 Flatulence
    R14.8 Other

## R15 Fecal incontinenceR15 Fecal incontinence

    Includes: encopresis NOS
    Excludes1: fecal incontinence of nonorganic origin (F98.1)

## R16 Hepatomegaly and splenomegaly, not elsewhere classifiedR16 Hepatomegaly and splenomegaly, not elsewhere classified

    R16.0 Hepatomegaly, not elsewhere classified
       Hepatomegaly NOS
    R16.1 Splenomegaly, not elsewhere classified
       Splenomegaly NOS
    R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
       Hepatosplenomegaly NOS

## R17 Unspecified jaundiceR17 Unspecified jaundice

    Excludes1: neonatal jaundice (P55, P57-P59)

## R18 AscitesR18 Ascites

    Includes: fluid in peritoneal cavity
    Excludes1: ascites in alcoholic cirrhosis (K70.31)
       ascites ​in alcoholic hepatitis (K70.11)
       ascites in toxic liver disease with chronic active hepatitis (K71.51)
    R18.0 Malignant ascites
       Code first malignancy, such as:
          malignant neoplasm of ovary (C56.-)
          secondary malignant neoplasm of retroperitoneum and peritoneum (C78.6)
    R18.8 Other ascites
       Ascites NOS
       Peritoneal effusion (chronic)

## R19 Other symptoms and signs involving the digestive system and abdomenR19 Other symptoms and signs involving the digestive system and abdomen

    Excludes1: acute abdomen (R10.0)
    R19.0 Intra-abdominal and pelvic swelling, mass and lump
       Excludes1: abdominal distension (gaseous) (R14.-)
          ascites (R18.-)
       R19.00 Intra-abdominal and pelvic swelling, mass and lump, unspecified site
       R19.01 Right upper quadrant abdominal swelling, mass and lump
       R19.02 Left upper quadrant abdominal swelling, mass and lump
       R19.03 Right lower quadrant abdominal swelling, mass and lump
       R19.04 Left lower quadrant abdominal swelling, mass and lump
       R19.05 Periumbilic swelling, mass or lump
          Diffuse or generalized umbilical swelling or mass
       R19.06 Epigastric swelling, mass or lump
       R19.07 Generalized intra-abdominal and pelvic swelling, mass and lump
          Diffuse or generalized intra-abdominal swelling or mass NOS
          Diffuse or generalized pelvic swelling or mass NOS
       R19.09 Other intra-abdominal and pelvic swelling, mass and lump
    R19.1 Abnormal bowel sounds
       R19.11 Absent bowel sounds
       R19.12 Hyperactive bowel sounds
       R19.15 Other abnormal bowel sounds
          Abnormal bowel sounds NOS
    R19.2 Visible peristalsis
       Hyperperistalsis
    R19.3 Abdominal rigidity
       Excludes1: abdominal rigidity with severe abdominal pain (R10.0)
       R19.30 Abdominal rigidity, unspecified site
       R19. ​31 Right upper quadrant abdominal rigidity
       R19.32 Left upper quadrant abdominal rigidity
       R19.33 Right lower quadrant abdominal rigidity
       R19.34 Left lower quadrant abdominal rigidity
       R19.35 Periumbilic abdominal rigidity
       R19.36 Epigastric abdominal rigidity
       R19.37 Generalized abdominal rigidity
    R19.4 Change in bowel habit
       Excludes1: constipation (K59.0-)
          functional diarrhea (K59.1)
    R19.5 Other fecal abnormalities
       Abnormal stool color
       Bulky stools
       Mucus in stools
       Occult blood in feces
       Occult blood in stools
       Excludes1: melena (K92.1)
          neonatal melena (P54.1)
    R19.6 Halitosis
    R19.7 Diarrhea, unspecified
       Diarrhea NOS
       Excludes1: functional diarrhea (K59.1)
          neonatal diarrhea (P78.3)
          psychogenic diarrhea (F45.8)
    R19.8 Other specified symptoms and signs involving the digestive system and abdomen

# Symptoms and signs involving the skin and subcutaneous tissue (R20-R23)Symptoms and signs involving the skin and subcutaneous tissue (R20-R23)

    Excludes2: symptoms relating to breast (N64.4-N64.5)

## R20 Disturbances of skin sensationR20 Disturbances of skin sensation

    Excludes1: dissociative anesthesia and sensory loss (F44.6)
       psychogenic disturbances (F45.8)
    R20.0 Anesthesia of skin
    R20.1 Hypoesthesia of skin
    R20.2 Paresthesia of skin
       Formication
       Pins and needles
       Tingling skin
       Excludes1: acroparesthesia (I73.8)
    R20.3 Hyperesthesia
    R20.8 Other disturbances of skin sensation
    R20.9 Unspecified disturbances of skin sensation

## R21 ​Rash and other nonspecific skin eruption

    Rash NOS
    Excludes1: specified type of rash- code to condition
       vesicular eruption (R23.8)

## R22 Localized swelling, mass and lump of skin and subcutaneous tissueR22 Localized swelling, mass and lump of skin and subcutaneous tissue

    Includes: subcutaneous nodules (localized)(superficial)
    Excludes1: abnormal findings on diagnostic imaging (R90-R93)
       edema (R60.-)
       enlarged lymph nodes (R59.-)
       localized adiposity (E65)
       swelling of joint (M25.4-)
    R22.0 Localized swelling, mass and lump, head
    R22.1 Localized swelling, mass and lump, neck
    R22.2 Localized swelling, mass and lump, trunk
       Excludes1: intra-abdominal or pelvic mass and lump (R19.0-)
          intra-abdominal or pelvic swelling (R19.0-)
       Excludes2: breast mass and lump (N63)
    R22.3 Localized swelling, mass and lump, upper limb
       R22.30 Localized swelling, mass and lump, upper limb, unspecified side
       R22.31 Localized swelling, mass and lump, right upper limb
       R22.32 Localized swelling, mass and lump, left upper limb
       R22.33 Localized swelling, mass and lump, upper limb, bilateral
    R22.4 Localized swelling, mass and lump, lower limb
       R22.40 Localized swelling, mass and lump, lower limb, unspecified side
       R22.41 Localized swelling, mass and lump, right lower limb
       R22.42 Localized swelling, mass and lump, left lower limb
       R22.43 Localized swelling, mass and lump, lower limb, bilateral
    R22.9 Localized swelling, mass and lump, unspecified

## R23 Other skin changesR23 Other skin changes

    R23.0 Cyanosis
       Excludes1: acrocyanosis (I73.8)
          cyanotic attacks of newborn (P28.2)
    R23.1 Pallor
       Clammy skin
    R23.2 Flushing
       Excessive blushing
       Code first, if applicable, menopausal and female climacteric states (N95.1)
    R23.3 Spontaneous ecchymoses
       Petechiae
       Excludes1: ​ecchymoses of newborn (P54.5)
          purpura (D69.-)
    R23.4 Changes in skin texture
       Desquamation of skin
       Induration of skin
       Scaling of skin
       Excludes1: epidermal thickening NOS (L85.9)
    R23.8 Other skin changes
    R23.9 Unspecified skin changes

# Symptoms and signs involving the nervous and musculoskeletal systems (R25-R29)Symptoms and signs involving the nervous and musculoskeletal systems (R25-R29)
## R25 Abnormal involuntary movementsR25 Abnormal involuntary movements

    Excludes1: specific movement disorders (G20-G26)
       stereotyped movement disorders (F98.4)
       tic disorders (F95.-)
    R25.0 Abnormal head movements
    R25.1 Tremor, unspecified
       Excludes1: chorea NOS (G25.5)
          essential tremor (G25.0)
          hysterical tremor (F44.4)
          intention tremor (G25.2)
    R25.2 Cramp and spasm
       Excludes2: carpopedal spasm (R29.0)
          charley-horse (M62.831)
          infantile spasms (G40.4-)
          muscle spasm of back (M62.830)
          muscle spasm of calf (M62.831)
    R25.3 Fasciculation
       Twitching NOS
    R25.8 Other abnormal involuntary movements
    R25.9 Unspecified abnormal involuntary movements

## R26 Abnormalities of gait and mobilityR26 Abnormalities of gait and mobility

    Excludes1: ataxia NOS (R27.0)
       hereditary ataxia (G11.-)
       locomotor (syphilitic) ataxia (A52.11)
       immobility syndrome (paraplegic) (M62.3)
    R26.0 Ataxic gait
       Staggering gait
    R26.1 Paralytic gait
       Spastic gait
    R26.2 Difficulty in walking, not elsewhere classified
       Excludes1: falling (R29.6)
          unsteadiness ​on feet (R26.81)
    R26.8 Other abnormalities of gait and mobility
       R26.81 Unsteadiness on feet
       R26.89 Other abnormalities of gait and mobility
    R26.9 Unspecified abnormalities of gait and mobility

## R27 Other lack of coordinationR27 Other lack of coordination

    Excludes1: ataxic gait (R26.0)
       hereditary ataxia (G11.-)
       vertigo NOS (R42)
    R27.0 Ataxia, unspecified
       Excludes1: ataxia following cerebrovascular disease (I69. with final characters -93)
    R27.8 Other lack of coordination
    R27.9 Unspecified lack of coordination

## R29 Other symptoms and signs involving the nervous and musculoskeletal systemsR29 Other symptoms and signs involving the nervous and musculoskeletal systems

    R29.0 Tetany
       Carpopedal spasm
       Excludes1: hysterical tetany (F44.5)
          neonatal tetany (P71.3)
          parathyroid tetany (E20.9)
          post-thyroidectomy tetany (E89.2)
    R29.1 Meningismus
    R29.2 Abnormal reflex
       Excludes2: abnormal pupillary reflex (H57.0)
          hyperactive gag reflex (J39.2)
          vasovagal reaction or syncope (R55)
    R29.3 Abnormal posture
    R29.4 Clicking hip
       Excludes1: congenital deformities of hip (Q65.-)
    R29.5 Transient paralysis
       Code first any associated spinal cord injury (S14.0, S14.1-, S24.0, S24.1-, S34.0, S34.1-)
       Excludes1: transient ischemic attack (G45.9)
    R29.6 Repeated falls
       Falling
       Tendency to fall
       Excludes2: at risk for falling (Z91.81)
          history of falling (Z91.81)
    R29.8 Other symptoms and signs involving the nervous and musculoskeletal systems
       R29.81 Other symptoms and signs involving the nervous system
          R29.810 Facial weakness
             Facial droop
             Excludes1: ​Bell's palsy (G51.0)
                facial weakness following cerebrovascular disease (I69. with final characters -92)
          R29.818 Other symptoms and signs involving the nervous system
       R29.89 Other symptoms and signs involving the musculoskeletal system
          Excludes2: pain in limb (M79.6-)
          R29.890 Loss of height
             Excludes1: osteoporosis (M80-M82)
          R29.891 Ocular torticollis
             Excludes1: congenital (sternomastoid) torticollis Q68.0
                psychogenic torticollis (F45.8)
                spasmodic torticollis (G24.3)
                torticollis due to birth injury (P15.8)
                torticollis NOS M43.6
          R29.898 Other symptoms and signs involving the musculoskeletal system
    R29.9 Unspecified symptoms and signs involving the nervous and musculoskeletal systems
       R29.90 Unspecified symptoms and signs involving the nervous system
       R29.91 Unspecified symptoms and signs involving the musculoskeletal system

# Symptoms and signs involving the genitourinary system (R30-R39)Symptoms and signs involving the genitourinary system (R30-R39)
## R30 Pain associated with micturitionR30 Pain associated with micturition

    Excludes1: psychogenic pain associated with micturition (F45.8)
    R30.0 Dysuria
       Strangury
    R30.1 Vesical tenesmus
    R30.9 Painful micturition, unspecified
       Painful urination NOS

## R31 HematuriaR31 Hematuria

    Excludes1: hematuria included with underlying conditions, such as:
       acute cystitis with hematuria (N30.01)
       acute prostatitis with hematuria (N41.01)
       recurrent and persistent hematuria in glomerular diseases (N02.-)
    R31.0 Gross hematuria
    R31. ​1 Benign essential microscopic hematuria
    R31.2 Other microscopic hematuria
    R31.9 Hematuria, unspecified

## R32 Unspecified urinary incontinenceR32 Unspecified urinary incontinence

    Includes: enuresis NOS
    Excludes1: functional urinary incontinence (R39.81)
       nonorganic enuresis (F98.0)
       stress incontinence and other specified urinary incontinence (N39.3-N39.4-)
       urinary incontinence associated with cognitive impairment (R39.81)

## R33 Retention of urineR33 Retention of urine

    Excludes1: psychogenic retention of urine (F45.8)
    R33.0 Drug induced retention of urine
       Code first (T36-T50) to identify the drug
    R33.8 Other retention of urine
       Code, if applicable, any causal condition first, such as:
          enlarged prostate (N40.1)
    R33.9 Retention of urine, unspecified

## R34 Anuria and oliguriaR34 Anuria and oliguria

    Excludes1: anuria and oliguria complicating abortion or ectopic or molar pregnancy (O00-O07, O08.4)
       anuria and oliguria complicating pregnancy (O26.83-)
       anuria and oliguria complicating the puerperium (O90.4)

## R35 PolyuriaR35 Polyuria

    Code, if applicable, any causal condition first, such as:
       enlarged prostate (N40.1)
    Excludes1: psychogenic polyuria (F45.8)
    R35.0 Frequency of micturition
    R35.1 Nocturia
    R35.8 Other polyuria
       Polyuria NOS

## R36 Urethral dischargeR36 Urethral discharge

    R36.0 Urethral discharge without blood
    R36.1 Hematospermia
    R36.9 Urethral discharge, unspecified
       Penile discharge NOS
       Urethrorrhea

## R39 Other and unspecified symptoms and signs involving the genitourinary systemR39 Other and unspecified symptoms and signs involving the genitourinary system

    R39.0 Extravasation of urine
    R39. ​1 Other difficulties with micturition
       Code, if applicable, any causal condition first, such as:
          enlarged prostate (N40.1)
       R39.11 Hesitancy of micturition
       R39.12 Poor urinary stream
          Weak urinary steam
       R39.13 Splitting of urinary stream
       R39.14 Feeling of incomplete bladder emptying
       R39.15 Urgency of urination
          Excludes1 urge incontinence (N39.41, N39.46)
       R39.16 Straining to void
       R39.19 Other difficulties with micturition
    R39.2 Extrarenal uremia
       Prerenal uremia
       Excludes1: uremia NOS (N19)
    R39.8 Other symptoms and signs involving the genitourinary system
       R39.81 Functional urinary incontinence
          Urinary incontinence due to cognitive impairment, or severe physical disability or immobility
          Excludes1: stress incontinence and other specified urinary incontinence (N39.3-N39.4-)
             urinary incontinence NOS (R32)
       R39.89 Other symptoms and signs involving the genitourinary system
    R39.9 Unspecified symptoms and signs involving the genitourinary system

# Symptoms and signs involving cognition, perception, emotional state and behavior (R40-R46)Symptoms and signs involving cognition, perception, emotional state and behavior (R40-R46)

    Excludes1: symptoms and signs constituting part of a pattern of mental disorder (F01-F99)

## R40 Somnolence, stupor and comaR40 Somnolence, stupor and coma

    Excludes1: neonatal coma (P91.5)
       somnolence, stupor and coma in diabetes (E08-E13)
       somnolence, stupor and coma in hepatic failure (K72.-)
       somnolence, stupor and coma in hypoglycemia (nondiabetic) (E15)
    R40.0 Somnolence
       Drowsiness
       Excludes1: coma (R40.2-)
    R40.1 Stupor
       Catatonic stupor
       Semicoma
       Excludes1: catatonic schizophrenia (F20.2)
          coma (R40.2-)
          depressive ​stupor (F31-F33)
          dissociative stupor (F44.2)
          manic stupor (F30.2)
    R40.2 Coma
       Coma NOS
       Unconsciousness NOS
       Codes first any associated:
          coma in fracture of skull (S02.-)
          coma in intracranial injury (S06.-)
       The appropriate 7th character is to be added to each code from subcategory R40.21-, R40.22-, R40.23-:
       0 unspecified time
       1 in the field [EMT or ambulance]
       2 at arrival to emergency department
       3 at hospital admission
       4 24 hours or more after hospital admission
       A code from each subcategory is required to complete the coma scale
       Note: These codes are intended primarily for trauma registry and research use but may be utilized by all users of the classification who wish to collect this information
       R40.20 Unspecified coma
       R40.21 Coma scale, eyes open
          R40.211 Coma scale, eyes open, never
          R40.212 Coma scale, eyes open, to pain
          R40.213 Coma scale, eyes open, to sound
          R40.214 Coma scale, eyes open, spontaneous
       R40.22 Coma scale, best verbal response
          R40.221 Coma scale, best verbal response, none
          R40.222 Coma scale, best verbal response, incomprehensible words
          R40.223 Coma scale, best verbal response, inappropriate words
          R40.224 Coma scale, best verbal response, confused conversation
          R40.225 Coma scale, best verbal response, oriented
       R40.23 Coma scale, best motor response
          R40.231 Coma scale, best motor response, none
          R40.232 Coma scale, best motor response, extension
          R40.233 Coma scale, best motor response, abnormal
          R40.234 Coma scale, best motor response, flexion withdrawal
          R40.235 Coma scale, best motor response, localizes pain
          R40. ​236 Coma scale, best motor response, obeys commands
    R40.3 Persistent vegetative state
    R40.4 Transient alteration of awareness

## R41 Other symptoms and signs involving cognitive functions and awarenessR41 Other symptoms and signs involving cognitive functions and awareness

    Excludes1: dissociative [conversion] disorders (F44.-)
    R41.0 Disorientation, unspecified
       Confusion NOS
       Delirium NOS
    R41.1 Anterograde amnesia
    R41.2 Retrograde amnesia
    R41.3 Other amnesia
       Amnesia NOS
       Memory loss NOS
       Excludes1: amnestic disorder due to known physiologic condition (F04)
          amnestic syndrome due to psychoactive substance use (F10-F19 with 5th character .6)
          transient global amnesia (G45.4)
    R41.4 Neurologic neglect syndrome
       Asomatognosia
       Hemi-akinesia
       Hemi-inattention
       Hemispatial neglect
       Left-sided neglect
       Sensory neglect
       Visuospatial neglect
    R41.8 Other symptoms and signs involving cognitive functions and awareness
       R41.81 Age-related cognitive decline
          Senility NOS
       R41.82 Altered mental status, unspecified
          Change in mental status NOS
          Excludes1: altered level of consciousness (R40.-)
             altered mental status due to known condition - code to condition
             delirium NOS (R41.0)
       R41.83 Borderline intellectual functioning
          IQ level 71 to 84
          Excludes1: mental retardation (F70-F79)
       R41.89 Other symptoms and signs involving cognitive functions and awareness
          Anosognosia
    R41.9 Unspecified symptoms and signs involving cognitive functions and awareness

## R42 ​Dizziness and giddiness

    Includes: light-headedness
       vertigo NOS
    Excludes1: vertiginous syndromes (H81.-)
       vertigo from infrasound (T75.23)

## R43 Disturbances of smell and tasteR43 Disturbances of smell and taste

    R43.0 Anosmia
    R43.1 Parosmia
    R43.2 Parageusia
    R43.8 Other disturbances of smell and taste
       Mixed disturbance of smell and taste
    R43.9 Unspecified disturbances of smell and taste

## R44 Other symptoms and signs involving general sensations and perceptionsR44 Other symptoms and signs involving general sensations and perceptions

    Excludes1: alcoholic hallucinations (F1.5)
       hallucinations in drug psychosis (F11-F19 with .5)
       hallucinations in mood disorders with psychotic symptoms (F30.2, F31.5, F32.3, F33.3)
       hallucinations in schizophrenia, schizotypal and delusional disorders (F20-F29)
    Excludes2: disturbances of skin sensation (R20.-)
    R44.0 Auditory hallucinations
    R44.1 Visual hallucinations
    R44.2 Other hallucinations
    R44.3 Hallucinations, unspecified
    R44.8 Other symptoms and signs involving general sensations and perceptions
    R44.9 Unspecified symptoms and signs involving general sensations and perceptions

## R45 Symptoms and signs involving emotional stateR45 Symptoms and signs involving emotional state

    R45.0 Nervousness
       Nervous tension
    R45.1 Restlessness and agitation
    R45.2 Unhappiness
    R45.3 Demoralization and apathy
       Excludes1: anhedonia (R45.84)
    R45.4 Irritability and anger
    R45.5 Hostility
    R45.6 Violent behavior
    R45.7 State of emotional shock and stress, unspecified
    R45.8 Other symptoms and signs involving emotional state
       R45.81 Low self-esteem
       R45.82 Worries
       R45.83 Excessive crying of child, adolescent or adult
          Excludes1: ​excessive crying of infant (baby) R68.11
       R45.84 Anhedonia
       R45.85 Suicidal ideation
          Excludes1: suicide attempt (T14.91)
       R45.86 Emotional lability
       R45.87 Impulsiveness
       R45.89 Other symptoms and signs involving emotional state

## R46 Symptoms and signs involving appearance and behaviorR46 Symptoms and signs involving appearance and behavior

    Excludes1: appearance and behavior in schizophrenia, schizotypal and delusional disorders (F20-F29)
       mental and behavioral disorders (F01-F99)
    R46.0 Very low level of personal hygiene
    R46.1 Bizarre personal appearance
    R46.2 Strange and inexplicable behavior
    R46.3 Overactivity
    R46.4 Slowness and poor responsiveness
       Excludes1: stupor (R40.1)
    R46.5 Suspiciousness and marked evasiveness
    R46.6 Undue concern and preoccupation with stressful events
    R46.7 Verbosity and circumstantial detail obscuring reason for contact
    R46.8 Other symptoms and signs involving appearance and behavior
       R46.81 Obsessive-compulsive behavior
          Excludes1: obsessive-compulsive disorder (F42)
       R46.89 Other symptoms and signs involving appearance and behavior
          Symptoms and signs involving speech and voice (R47-R49)

## R47 Speech disturbances, not elsewhere classifiedR47 Speech disturbances, not elsewhere classified

    Excludes1: autism (F84.0)
       cluttering (F98.8)
       specific developmental disorders of speech and language (F80.-)
       stuttering [stammering] (F98.5)
    R47.0 Dysphasia and aphasia
       R47.01 Aphasia
          Excludes1: aphasia following cerebrovascular disease (I69. with final characters -20)
             progressive isolated aphasia (G31.01)
       R47.02 Dysphasia
          Excludes1: dysphasia following cerebrovascular disease (I69. with final characters -21)
    R47.1 Dysarthria and anarthria
       Excludes1: ​dyarthria following cerebrovascular disease (I69. with final characters -22)
    R47.8 Other speech disturbances
       Excludes1: dyarthria following cerebrovascular disease (I69. with final characters -28)
       R47.81 Slurred speech
       R47.89 Other speech disturbances
    R47.9 Unspecified speech disturbances

## R48 Dyslexia and other symbolic dysfunctions, not elsewhere classifiedR48 Dyslexia and other symbolic dysfunctions, not elsewhere classified

    Excludes1: specific developmental disorders of scholastic skills (F81.-)
    R48.0 Dyslexia and alexia
    R48.1 Agnosia
       Astereognosia (astereognosis)
       Autotopagnosia
       Excludes1: visual object agnosia H53.16
    R48.2 Apraxia
       Excludes1: apraxia following cerebrovascular disease (I69. with final characters -90)
    R48.8 Other symbolic dysfunctions
       Acalculia
       Agraphia
    R48.9 Unspecified symbolic dysfunctions

## R49 Voice and resonance disordersR49 Voice and resonance disorders

    Excludes1: psychogenic voice and resonance disorders (F44.4)
    R49.0 Dysphonia
       Hoarseness
    R49.1 Aphonia
       Loss of voice
    R49.2 Hypernasality and hyponasality
       R49.21 Hypernasality
       R49.22 Hyponasality
    R49.8 Other voice and resonance disorders
    R49.9 Unspecified voice and resonance disorder
       Change in voice NOS
       Resonance disorder NOS

# General symptoms and signs (R50-R69)General symptoms and signs (R50-R69)
## R50 Fever of other and unknown originR50 Fever of other and unknown origin

    Excludes1: febrile convulsions (R56.0-)
       fever of unknown origin during labor (O75.2)
       fever of unknown origin in newborn (P81.9)
       malignant hyperthermia due to anesthesia (T88.3)
       puerperal ​pyrexia NOS (O86.4)
    R50.2 Drug induced fever
       Code first (T36-T50) to identify drug
       Excludes1: postvaccination (postimmunization) fever (R50.83)
    R50.8 Other specified fever
       R50.81 Fever presenting with conditions classified elsewhere
          Code first underlying condition when associated fever is present, such as with:
             leukemia (C91-C95)
             neutropenia (D70.-)
             sickle cell disease (D57.-)
       R50.82 Postprocedural fever
          Excludes1: postprocedural infection (T81.4)
             postvaccination (postimmunization) fever (R50.83)
       R50.83 Postvaccination fever
          Postimmunization fever
    R50.9 Fever, unspecified
       Fever NOS
       Fever of unknown origin [FUO]
       Fever with chills
       Fever with rigors
       Hyperpyrexia NOS
       Persistent fever
       Pyrexia NOS

## R51 HeadacheR51 Headache

    Includes: facial pain NOS
    Excludes1: atypical face pain (G50.1)
       migraine and other headache syndromes (G43-G44)
       trigeminal neuralgia (G50.0)

## R52 Pain, unspecifiedR52 Pain, unspecified

    Acute pain NOS
    Chronic pain NOS
    Generalized pain NOS
    Pain NOS
    Excludes1: acute and chronic pain, not elsewhere classified (G89.-)
       localized pain, unspecified type - code to pain by site, such as:
       abdomen pain (R10.-)
       back pain (M54.9)
       breast pain (N64.4)
       chest pain (R07.1-R07.9)
       ear pain (H92.0-)
       eye pain (H57.1)
       headache (R51)
       joint ​pain (M25.5-)
       limb pain (M79.6-)
       lumbar region pain (M54.57)
       pelvic and perineal pain (R10.2)
       shoulder pain (M25.51-)
       spine pain (M54.-)
       throat pain (R07.0)
       tongue pain (K14.6)
       tooth pain (K08.8)
       renal colic (N23)
       pain disorders exclusively related to psychological factors (F45.41)

## R53 Malaise and fatigueR53 Malaise and fatigue

    R53.0 Neoplastic (malignant) related fatigue
       Code first associated neoplasm
    R53.1 Weakness
       Asthenia NOS
       Excludes1: age-related weakness (R54)
          muscle weakness (M62.8-)
          senile asthenia (R54)
    R53.2 Functional quadriplegia
       Complete immobility due to severe physical disability or frailty
       Excludes1: frailty NOS (R54)
          hysterical paralysis (F44.4)
          immobility syndrome (M62.3)
          neurologic quadriplegia (G82.5-)
          quadriplegia (G82.50)
    R53.8 Other malaise and fatigue
       Excludes1: combat exhaustion and fatigue (F43.0)
          congenital debility (P96.9)
          exhaustion and fatigue due to:
          depressive episode (F32.-)
          excessive exertion (T73.3)
          exposure (T73.2)
          heat (T67.-)
          pregnancy (O26.8-)
          recurrent depressive episode (F33)
          senile debility (R54)
       R53.81 Other malaise
          Chronic debility
          Debility NOS
          General physical deterioration
          Malaise NOS
          Nervous debility
          Excludes1: age-related physical debility (R54)
       R53.82 Chronic fatigue, unspecified
          Chronic ​fatigue syndrome NOS
          Excludes1: postviral fatigue syndrome (G93.3)
       R53.83 Other fatigue
          Fatigue NOS
          Lack of energy
          Lethargy
          Tiredness

## R54 Age-related physical debilityR54 Age-related physical debility

    Frailty
    Old age
    Senescence
    Senile asthenia
    Senile debility
    Excludes1: age-related cognitive decline (R41.81)
       senile psychosis (F03)
       senility NOS (R41.81)

## R55 Syncope and collapseR55 Syncope and collapse

    Includes: blackout
       fainting
       vasovagal attack
    Excludes1: cardiogenic shock (R57.0)
       carotid sinus syncope (G90.01)
       heat syncope (T67.1)
       neurocirculatory asthenia (F45.3)
       neurogenic orthostatic hypotension (G90.3)
       orthostatic hypotension (I95.1)
       postprocedural shock (T81.1)
       psychogenic syncope (F48.8)
       shock NOS (R57.9)
       shock complicating or following abortion or ectopic or molar pregnancy (O00-O07, O08.3)
       shock complicating or following labor and delivery (O75.1)
       Stokes-Adams attack (I45.9)
       unconsciousness NOS (R40.2-)

## R56 Convulsions, not elsewhere classifiedR56 Convulsions, not elsewhere classified

    Excludes1: dissociative convulsions and seizures (F44.5)
       epileptic convulsions and seizures (G40.-)
       newborn convulsions and seizures (P90)
    R56.0 Febrile convulsions
       R56.00 Simple febrile convulsions
          Febrile convulsion NOS
          Febrile seizure NOS
       R56.01 Complex febrile convulsions
          Atypical febrile seizure
          Complex ​febrile seizure
          Complicated febrile seizure
          Excludes1: status epilepticus (G40.901)
    R56.9 Unspecified convulsions
       Convulsion disorder
       Fit NOS
       Recurrent convulsions
       Seizure(s) (convulsive) NOS

## R57 Shock, not elsewhere classifiedR57 Shock, not elsewhere classified

    Excludes1: anaphylactic shock NOS (T78.2)
       anaphylactic shock (reaction) due to adverse food reaction (T78.0-)
       anaphylactic shock due to serum (T80.5)
       anesthetic shock (T88.3)
       electric shock (T75.4)
       obstetric shock (O75.1)
       postprocedural shock (T81.1)
       psychic shock (F43.0)
       septic shock (R65.21)
       shock complicating or following ectopic or molar pregnancy (O00-O07, O08.3)
       shock due to lightning (T75.0)
       traumatic shock (T79.4)
       toxic shock syndrome (A48.3)
    R57.0 Cardiogenic shock
    R57.1 Hypovolemic shock
    R57.8 Other shock
    R57.9 Shock, unspecified
       Failure of peripheral circulation NOS

## R58 Hemorrhage, not elsewhere classifiedR58 Hemorrhage, not elsewhere classified

    Includes: hemorrhage NOS
    Excludes1: hemorrhage included with underlying conditions, such as:
       acute duodenal ulcer with hemorrhage (K26.0)
       acute gastritis with bleeding (K29.01)
       ulcerative enterocolitis with rectal bleeding (K51.01)

## R59 Enlarged lymph nodesR59 Enlarged lymph nodes

    Includes: swollen glands
    Excludes1: lymphadenitis NOS (I88.9)
       acute lymphadenitis (L04.-)
       chronic lymphadenitis (I88.1)
       mesenteric (acute) (chronic) lymphadenitis (I88.0)
    R59.0 Localized enlarged lymph nodes
    R59.1 Generalized enlarged lymph nodes
       Lymphadenopathy NOS
    R59.9 Enlarged lymph nodes, unspecified

## R60 ​Edema, not elsewhere classified

    Excludes1: angioneurotic edema (T78.3)
       ascites (R18.-)
       cerebral edema (G93.6)
       cerebral edema due to birth injury (P11.0)
       edema of larynx (J38.4)
       edema of nasopharynx (J39.2)
       edema of pharynx (J39.2)
       gestational edema (O12.0-)
       hereditary edema (Q82.0)
       hydrops fetalis NOS (P83.2)
       hydrothorax (J94.8)
       nutritional edema (E40-E46)
       hydrops fetalis NOS (P83.2)
       newborn edema (P83.3)
       pulmonary edema (J81.-)
    R60.0 Localized edema
    R60.1 Generalized edema
    R60.9 Edema, unspecified
       Fluid retention NOS

## R61 Generalized hyperhidrosisR61 Generalized hyperhidrosis

    Excessive sweating
    Night sweats
    Secondary hyperhidrosis
    Code first, if applicable, menopausal and female climacteric states (N95.1)
    Excludes1: focal (primary) (secondary) hyperhidrosis (L74.5-)
       Frey's syndrome (L74.52)
       localized (primary) (secondary) hyperhidrosis (L74.5-)

## R62 Lack of expected normal physiological development in childhood and adultsR62 Lack of expected normal physiological development in childhood and adults

    Excludes1: delayed puberty (E30.0)
       gonadal dysgenesis (Q99.1)
       hypopituitarism (E23.0)
    R62.0 Delayed milestone in childhood
       Delayed attainment of expected physiological developmental stage
       Late talker
       Late walker
    R62.5 Other and unspecified lack of expected normal physiological development in childhood
       Excludes1: HIV disease resulting in failure to thrive (B20)
          physical retardation due to malnutrition (E45)
       R62.50 Unspecified lack of expected normal physiological development in childhood
          Infantilism NOS
       R62. ​51 Failure to thrive (child)
          Failure to gain weight
          Excludes1: failure to thrive in child under 28 days old (P92.6)
       R62.52 Short stature (child)
          Lack of growth
          Physical retardation
          Short stature NOS
          Excludes1: short stature due to endocrine disorder (E34.3)
       R62.59 Other lack of expected normal physiological development in childhood
    R62.7 Adult failure to thrive

## R63 Symptoms and signs concerning food and fluid intakeR63 Symptoms and signs concerning food and fluid intake

    Excludes1: bulimia NOS (F50.2)
       eating disorders of nonorganic origin (F50.-)
       malnutrition (E40-E46)
    R63.0 Anorexia
       Loss of appetite
       Excludes1: anorexia nervosa (F50.0-)
          loss of appetite of nonorganic origin (F50.8)
    R63.1 Polydipsia
       Excessive thirst
    R63.2 Polyphagia
       Excessive eating
       Hyperalimentation NOS
    R63.3 Feeding difficulties
       Feeding problem (elderly) (infant) NOS
       Excludes1: feeding problems of newborn (P92.-)
          infant feeding disorder of nonorganic origin (F98.2-)
    R63.4 Abnormal weight loss
    R63.5 Abnormal weight gain
       Excludes1: excessive weight gain in pregnancy (O26.0-)
          obesity (E66.-)
    R63.6 Underweight
       Use additional code to identify body mass index (BMI), if known (Z68.-)
       Excludes1: abnormal weight loss (R63.4)
          anorexia nervosa (F50.0-)
          malnutrition (E40-E46)
    R63.8 Other symptoms and signs concerning food and fluid intake

## R64 CachexiaR64 Cachexia

    Includes: wasting syndrome
    Code first underlying condition, if known
    Excludes1: abnormal weight loss (R63.4)
       nutritional marasmus (E41)

## R65 ​Symptoms and signs specifically associated with systemic inflammation and infection

    R65.1 Systemic inflammatory response syndrome (SIRS) of non-infectious origin
       Code first underlying condition
       Excludes1: sepsis- code to infection
          severe sepsis (R65.2)
       R65.10 Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
          Systemic inflammatory response syndrome (SIRS) NOS
       R65.11 Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
          Use additional code to identify specific acute organ dysfunction, such as:
             acute kidney failure (N17.-)
             acute respiratory failure (J96.0)
             critical illness myopathy (G72.81)
             critical illness polyneuropathy (G62.81)
             disseminated intravascular coagulopathy [DIC] (D65)
             encephalopathy (metabolic) (septic) (G93.41)
             hepatic failure (K72.0-)
    R65.2 Severe sepsis
       Infection with associated acute organ dysfunction
       Sepsis with acute organ dysfunction
       Sepsis with multiple organ dysfunction
       Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
       Code first underlying infection, such as:
          Infection following a procedure (T81.4)
          Infections following infusion, transfusion and therapeutic injection (T80.2)
          Sepsis following complete or unspecified spontaneous abortion (O03.87)
          Sepsis following ectopic and molar pregnancy (O08.82)
          Sepsis following incomplete spontaneous abortion (O03.37)
          Sepsis following (induced) termination of pregnancy (O04.87)
          Sepsis NOS A41.9
       Use additional code to identify specific acute organ dysfunction, such as:
          acute kidney failure (N17.-)
          acute respiratory failure (J96.0)
          critical illness myopathy (G72.81)
          critical ​illness polyneuropathy (G62.81)
          disseminated intravascular coagulopathy [DIC] (D65)
          encephalopathy (metabolic) (septic) (G93.41)
          hepatic failure (K72.0-)
       R65.20 Severe sepsis without septic shock
          Severe sepsis NOS
       R65.21 Severe sepsis with septic shock

## R68 Other general symptoms and signsR68 Other general symptoms and signs

    R68.0 Hypothermia, not associated with low environmental temperature
       Excludes1: hypothermia NOS (accidental) (T68)
          hypothermia due to anesthesia (T88.51)
          hypothermia due to low environmental temperature (T68)
          newborn hypothermia (P80.-)
    R68.1 Nonspecific symptoms peculiar to infancy
       Excludes1: colic, infantile (R10.43)
          neonatal cerebral irritability (P91.3)
          teething syndrome (K00.7)
       R68.11 Excessive crying of infant (baby)
          Excludes1: excessive crying of child, adolescent, or adult (R45.83)
       R68.12 Fussy infant (baby)
          Irritable infant
       R68.13 Apparent life threatening event in infant [ALTE]
          Apparent life threatening event in newborn
          Use additional code(s) for associated signs and symptoms
          Excludes1: signs and symptoms associated with a confirmed diagnosis - code to confirmed diagnosis
       R68.19 Other nonspecific symptoms peculiar to infancy
    R68.2 Dry mouth, unspecified
       Excludes1: dry mouth due to dehydration (E86.0)
          dry mouth due to sicca syndrome [Sj?gren] (M35.0-)
          salivary gland hyposecretion (K11.7)
    R68.3 Clubbing of fingers
       Clubbing of nails
       Excludes1: congenital clubfinger (Q68.1)
    R68.8 Other general symptoms and signs
       R68.81 Early satiety
       R68.82 Decreased libido
          Decreased sexual desire
       R68.83 Chills (without fever)
          Chills NOS
          Excludes1: chills with fever (R50.9)
       R68.89 Other general symptoms and signs

## R69 Illness NOSR69 Illness NOS

    Includes: ​unknown and unspecified cases of morbidity

# Abnormal findings on examination of blood, without diagnosis (R70-R79)Abnormal findings on examination of blood, without diagnosis (R70-R79)

    Excludes1: abnormalities (of)(on):
       abnormal findings on antenatal screening of mother (O28.-)
       coagulation hemorrhagic disorders (D65-D68)
       lipids (E78.-)
       platelets and thrombocytes (D69.-)
       white blood cells classified elsewhere (D70-D72)
       diagnostic abnormal findings classified elsewhere - see Alphabetical Index
       hemorrhagic and hematological disorders of newborn (P50-P61)

## R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosityR70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

    R70.0 Elevated erythrocyte sedimentation rate
    R70.1 Abnormal plasma viscosity

## R71 Abnormality of red blood cellsR71 Abnormality of red blood cells

    Excludes1: anemias (D50-D64)
       anemia of premature infant (P61.2)
       benign (familial) polycythemia (D75.0)
       congenital anemias (P61.2-P61.4)
       newborn anemia due to isoimmunization (P55.-)
       polycythemia neonatorum (P61.1)
       polycythemia NOS (D75.1)
       polycythemia vera (D45)
       secondary polycythemia (D75.1)
    R71.0 Precipitous drop in hematocrit
       Drop (precipitous) in hemoglobin
       Drop in hematocrit
    R71.8 Other abnormality of red blood cells
       Abnormal red-cell morphology NOS
       Abnormal red-cell volume NOS
       Anisocytosis
       Poikilocytosis

## R73 Elevated blood glucose levelR73 Elevated blood glucose level

    Excludes1: diabetes mellitus (E08-E13)
       diabetes mellitus in pregnancy, childbirth and the puerperium (O24.-)
       neonatal disorders (P70.0-P70.2)
       postsurgical hypoinsulinemia (E89.1)
    R73.0 Abnormal glucose
       Excludes1: abnormal glucose in pregnancy (O99.81-)
          diabetes mellitus (E08-E13)
          dysmetabolic ​syndrome X (E88.81)
          gestational diabetes (O24.4)
          glycosuria (R81)
          hypoglycemia (E16.2)
       R73.01 Impaired fasting glucose
          Elevated fasting glucose
       R73.02 Impaired glucose tolerance (oral)
          Elevated glucose tolerance
       R73.09 Other abnormal glucose
          Abnormal glucose NOS
          Abnormal non-fasting glucose tolerance
          Latent diabetes
          Prediabetes
    R73.9 Hyperglycemia, unspecified

## R74 Abnormal serum enzyme levelsR74 Abnormal serum enzyme levels

    R74.0 Nonspecific elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
    R74.8 Abnormal levels of other serum enzymes
       Abnormal level of acid phosphatase
       Abnormal level of alkaline phosphatase
       Abnormal level of amylase
       Abnormal level of lipase [triacylglycerol lipase]
    R74.9 Abnormal serum enzyme level, unspecified

## R75 Inconclusive laboratory evidence of human immunodeficiency virus [HIV]R75 Inconclusive laboratory evidence of human immunodeficiency virus [HIV]

    Includes: nonconclusive HIV-test finding in infants
    Excludes1: asymptomatic human immunodeficiency virus [HIV] infection status (Z21)
       human immunodeficiency virus [HIV] disease (B20)

## R76 Other abnormal immunological findings in serumR76 Other abnormal immunological findings in serum

    R76.0 Raised antibody titer
       Excludes1: isoimmunization in pregnancy (O36.0-O36.1)
          isoimmunization affecting newborn (P55.-)
    R76.1 Abnormal reaction to tuberculin test
       Abnormal result of Mantoux test
    R76.8 Other specified abnormal immunological findings in serum
       Raised level of immunoglobulins NOS
    R76.9 Abnormal immunological finding in serum, unspecified

## R77 Other abnormalities of plasma proteinsR77 Other abnormalities of plasma proteins

    Excludes1: disorders of plasma-protein metabolism (E88.0)
    R77.0 Abnormality of albumin
    R77.1 Abnormality of globulin
       Hyperglobulinemia NOS
    R77. ​2 Abnormality of alphafetoprotein
    R77.8 Other specified abnormalities of plasma proteins
    R77.9 Abnormality of plasma protein, unspecified

## R78 Findings of drugs and other substances, not normally found in bloodR78 Findings of drugs and other substances, not normally found in blood

    Excludes1: mental or behavioral disorders due to psychoactive substance use (F10-F19)
    R78.0 Finding of alcohol in blood
       Use additional external cause code (Y90.-), for detail regarding alcohol level.
    R78.1 Finding of opiate drug in blood
    R78.2 Finding of cocaine in blood
    R78.3 Finding of hallucinogen in blood
    R78.4 Finding of other drugs of addictive potential in blood
    R78.5 Finding of other psychotropic drug in blood
    R78.6 Finding of steroid agent in blood
    R78.7 Finding of abnormal level of heavy metals in blood
       R78.71 Abnormal lead level in blood
          Excludes1: lead poisoning (T56.0-)
       R78.79 Finding of abnormal level of heavy metals in blood
    R78.8 Finding of other specified substances, not normally found in blood
       R78.81 Bacteremia
          Excludes1: sepsis-code to specified infection (A00-B99)
       R78.89 Finding of other specified substances, not normally found in blood
          Finding of abnormal level of lithium in blood
    R78.9 Finding of unspecified substance, not normally found in blood

## R79 Other abnormal findings of blood chemistryR79 Other abnormal findings of blood chemistry

    Excludes1: abnormality of fluid, electrolyte or acid-base balance (E86-E87)
       asymptomatic hyperuricemia (E79.0)
       hyperglycemia NOS (R73.9)
       hypoglycemia NOS (E16.2)
       neonatal hypoglycemia (P70.3-P70.4)
       specific findings indicating disorder of:
       amino-acid metabolism (E70-E72)
       carbohydrate metabolism (E73-E74)
       lipid metabolism (E75.-)
    R79.0 Abnormal level of blood mineral
       Abnormal blood level of cobalt
       Abnormal blood level of copper
       Abnormal blood level of iron
       Abnormal blood level of magnesium
       Abnormal blood level of mineral NEC
       Abnormal ​blood level of zinc
       Excludes1: abnormal level of lithium (R78.89)
          disorders of mineral metabolism (E83.-)
          neonatal hypomagnesemia (P71.2)
          nutritional mineral deficiency (E58-E61)
    R79.1 Abnormal coagulation profile
       Abnormal or prolonged bleeding time
       Abnormal or prolonged coagulation time
       Abnormal or prolonged partial thromboplastin time [PTT]
       Abnormal or prolonged prothrombin time [PT]
       Excludes1: coagulation defects (D68.-)
    R79.8 Other specified abnormal findings of blood chemistry
       R79.81 Abnormal blood-gas level
       R79.82 Elevated C-reactive protein (CRP)
       R79.89 Other specified abnormal findings of blood chemistry
    R79.9 Abnormal finding of blood chemistry, unspecified

# Abnormal findings on examination of urine, without diagnosis (R80-R82)Abnormal findings on examination of urine, without diagnosis (R80-R82)

    Excludes1: abnormal findings on antenatal screening of mother (O28.-)
       diagnostic abnormal findings classified elsewhere - see Alphabetical Index
       specific findings indicating disorder of:
       amino-acid metabolism (E70-E72)
       carbohydrate metabolism (E73-E74)

## R80 ProteinuriaR80 Proteinuria

    Excludes1: gestational proteinuria (O12.1-)
    R80.0 Isolated proteinuria
       Idiopathic proteinuria
       Excludes1: isolated proteinuria with specific morphological lesion (N06.-)
    R80.1 Persistent proteinuria, unspecified
    R80.2 Orthostatic proteinuria, unspecified
       Postural proteinuria
    R80.3 Bence Jones proteinuria
    R80.8 Other proteinuria
    R80.9 Proteinuria NOS
       Albuminuria NOS

## R81 GlycosuriaR81 Glycosuria

    Excludes1: renal glycosuria (E74.8)

## R82 Other and unspecified abnormal findings in urineR82 Other and unspecified abnormal findings in urine

    Includes: chromoabnormalities in urine
    Excludes2: hematuria (R31.-)
    R82.0 Chyluria
       Excludes1: ​filarial chyluria (B74.-)
    R82.1 Myoglobinuria
    R82.2 Biliuria
    R82.3 Hemoglobinuria
       Excludes1: hemoglobinuria due to hemolysis from external causes NEC (D59.6)
          hemoglobinuria due to paroxysmal nocturnal [Marchiafava-Micheli] (D59.5)
    R82.4 Acetonuria
       Ketonuria
    R82.5 Elevated urine levels of drugs, medicaments and biological substances
       Elevated urine levels of catecholamines
       Elevated urine levels of indoleacetic acid
       Elevated urine levels of 17-ketosteroids
       Elevated urine levels of steroids
    R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source
       Abnormal urine level of heavy metals
    R82.7 Abnormal findings on microbiological examination of urine
       Positive culture findings of urine
       Excludes1: colonization status (Z22.-)
    R82.8 Abnormal findings on cytological and histological examination of urine
    R82.9 Other and unspecified abnormal findings in urine
       R82.90 Unspecified abnormal findings in urine
       R82.91 Other chromoabnormalities of urine
          Chromoconversion (dipstick)
          Idiopathic dipstick converts positive for blood with no cellular forms in sediment
          Excludes1: hemoglobinuria (R82.3)
             myoglobinuria (R82.1)
       R82.99 Other abnormal findings in urine
          Cells and casts in urine
          Crystalluria
          Melanuria

# Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)

    Excludes1: abnormal findings on antenatal screening of mother (O28.-)
       diagnostic abnormal findings classified elsewhere - see Alphabetical Index
    Excludes2: abnormal findings on examination of blood, without diagnosis (R70-R79)
       abnormal findings on examination of urine, without diagnosis (R80-R82)
       abnormal tumor markers (R97.-)

## R83 ​Abnormal findings in cerebrospinal fluid

    R83.0 Abnormal level of enzymes in cerebrospinal fluid
    R83.1 Abnormal level of hormones in cerebrospinal fluid
    R83.2 Abnormal level of other drugs, medicaments and biological substances in cerebrospinal fluid
    R83.3 Abnormal level of substances chiefly nonmedicinal as to source in cerebrospinal fluid
    R83.4 Abnormal immunological findings in cerebrospinal fluid
    R83.5 Abnormal microbiological findings in cerebrospinal fluid
       Positive culture findings in cerebrospinal fluid
       Excludes1: colonization status (Z22.-)
    R83.6 Abnormal cytological findings in cerebrospinal fluid
    R83.8 Other abnormal findings in cerebrospinal fluid
       Abnormal chromosomal findings in cerebrospinal fluid
    R83.9 Unspecified abnormal finding in cerebrospinal fluid

## R84 Abnormal findings in specimens from respiratory organs and thoraxR84 Abnormal findings in specimens from respiratory organs and thorax

    Includes: abnormal findings in bronchial washings
       abnormal findings in nasal secretions
       abnormal findings in pleural fluid
       abnormal findings in sputum
       abnormal findings in throat scrapings
    Excludes1: blood-stained sputum (R04.2)
    R84.0 Abnormal level of enzymes in specimens from respiratory organs and thorax
    R84.1 Abnormal level of hormones in specimens from respiratory organs and thorax
    R84.2 Abnormal level of other drugs, medicaments and biological substances in specimens from respiratory organs and thorax
    R84.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from respiratory organs and thorax
    R84.4 Abnormal immunological findings in specimens from respiratory organs and thorax
    R84.5 Abnormal microbiological findings in specimens from respiratory organs and thorax
       Positive culture findings in specimens from respiratory organs and thorax
       Excludes1: colonization status (Z22.-)
    R84.6 Abnormal cytological findings in specimens from respiratory organs and thorax
    R84.7 Abnormal histological findings in specimens from respiratory organs and thorax
    R84.8 Other abnormal findings in specimens from respiratory organs and thorax
       Abnormal chromosomal findings in specimens from respiratory organs and thorax
    R84. ​9 Unspecified abnormal finding in specimens from respiratory organs and thorax

## R85 Abnormal findings in specimens from digestive organs and abdominal cavityR85 Abnormal findings in specimens from digestive organs and abdominal cavity

    Includes: abnormal findings in peritoneal fluid
       abnormal findings in saliva
    Excludes1: cloudy peritoneal dialysis effluent (R88.0)
       fecal abnormalities (R19.5)
    R85.0 Abnormal level of enzymes in specimens from digestive organs and abdominal cavity
    R85.1 Abnormal level of hormones in specimens from digestive organs and abdominal cavity
    R85.2 Abnormal level of other drugs, medicaments and biological substances in specimens from digestive organs and abdominal cavity
    R85.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity
    R85.4 Abnormal immunological findings in specimens from digestive organs and abdominal cavity
    R85.5 Abnormal microbiological findings in specimens from digestive organs and abdominal cavity
       Positive culture findings in specimens from digestive organs and abdominal cavity
       Excludes1: colonization status (Z22.-)
    R85.6 Abnormal cytological findings in specimens from digestive organs and abdominal cavity
       R85.61 Abnormal cytologic smear of anus
          Excludes1: abnormal cytological findings in specimens from other digestive organs and abdominal cavity (R85.69)
             carcinoma in situ of anus (histologically confirmed) (D01.3)
             anal intraepithelial neoplasia I [AIN I] (K62.82)
             anal intraepithelial neoplasia II [AIN II] (K62.82)
             anal intraepithelial neoplasia III [AIN III] (D01.3)
             dysplasia (mild) (moderate) of anus (histologically confirmed) (K62.82)
             severe dysplasia of anus (histologically confirmed) (D01.3)
          Excludes2: anal high risk human papillomavirus (HPV) DNA test positive (R85.81)
             anal low risk human papillomavirus (HPV) DNA test positive (R85.82)
          R85. ​610 Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US)
          R85.611 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of anus (ASC-H)
          R85.612 Low grade squamous intraepithelial lesion on cytologic smear of anus (LGSIL)
          R85.613 High grade squamous intraepithelial lesion on cytologic smear of anus (HGSIL)
          R85.614 Cytologic evidence of malignancy on smear of anus
          R85.615 Unsatisfactory cytologic smear of anus
             Inadequate sample of cytologic smear of anus
          R85.616 Satisfactory anal smear but lacking transformation zone
          R85.618 Other abnormal cytological findings on specimens from anus
          R85.619 Unspecified abnormal cytological findings in specimens from anus
             Abnormal anal cytology NOS
             Atypical glandular cells of anus NOS
       R85.69 Abnormal cytological findings in specimens from other digestive organs and abdominal cavity
    R85.7 Abnormal histological findings in specimens from digestive organs and abdominal cavity
    R85.8 Other abnormal findings in specimens from digestive organs and abdominal cavity
       R85.81 Anal high risk human papillomavirus (HPV) DNA test positive
          Excludes1: anogenital warts due to human papillomavirus (HPV) (A63.0)
             condyloma acuminatum (A63.0)
       R85.82 Anal low risk human papillomavirus (HPV) DNA test positive
          Use additional code for associated human papillomavirus (B97.7)
       R85.89 Other abnormal findings in specimens from digestive organs and abdominal cavity
          Abnormal chromosomal findings in specimens from digestive organs and abdominal cavity
    R85.9 Unspecified abnormal finding in specimens from digestive organs and abdominal cavity

## R86 Abnormal findings in specimens from male genital organsR86 Abnormal findings in specimens from male genital organs

    Includes: abnormal findings in prostatic secretions
       abnormal findings in semen, seminal fluid
       abnormal ​spermatozoa
    Excludes1: azoospermia (N46.0-)
       oligospermia (N46.1-)
    R86.0 Abnormal level of enzymes in specimens from male genital organs
    R86.1 Abnormal level of hormones in specimens from male genital organs
    R86.2 Abnormal level of other drugs, medicaments and biological substances in specimens from male genital organs
    R86.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from male genital organs
    R86.4 Abnormal immunological findings in specimens from male genital organs
    R86.5 Abnormal microbiological findings in specimens from male genital organs
       Positive culture findings in specimens from male genital organs
       Excludes1: colonization status (Z22.-)
    R86.6 Abnormal cytological findings in specimens from male genital organs
    R86.7 Abnormal histological findings in specimens from male genital organs
    R86.8 Other abnormal findings in specimens from male genital organs
       Abnormal chromosomal findings in specimens from male genital organs
    R86.9 Unspecified abnormal finding in specimens from male genital organs

## R87 Abnormal findings in specimens from female genital organsR87 Abnormal findings in specimens from female genital organs

    Includes: abnormal findings in secretion and smears from cervix uteri
       abnormal findings in secretion and smears from vagina
       abnormal findings in secretion and smears from vulva
    R87.0 Abnormal level of enzymes in specimens from female genital organs
    R87.1 Abnormal level of hormones in specimens from female genital organs
    R87.2 Abnormal level of other drugs, medicaments and biological substances in specimens from female genital organs
    R87.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from female genital organs
    R87.4 Abnormal immunological findings in specimens from female genital organs
    R87.5 Abnormal microbiological findings in specimens from female genital organs
       Positive culture findings in specimens from female genital organs
       Excludes1: colonization status (Z22.-)
    R87. ​6 Abnormal cytological findings in specimens from female genital organs
       R87.61 Abnormal cytological findings in specimens from cervix uteri
          Excludes1: abnormal cytological findings in specimens from other female genital organs (R87.69)
             abnormal cytological findings in specimens from vagina (R87.62-)
             carcinoma in situ of cervix uteri (histologically confirmed) (D06.-)
             cervical intraepithelial neoplasia I [CIN I] (N87.0)
             cervical intraepithelial neoplasia II [CIN II] (N87.1)
             cervical intraepithelial neoplasia III [CIN III] (D06.-)
             dysplasia (mild) (moderate) of cervix uteri (histologically confirmed) (N87.-)
             severe dysplasia of cervix uteri (histologically confirmed) (D06.-)
          Excludes2: cervical high risk human papillomavirus (HPV) DNA test positive (R87.810)
             cervical low risk human papillomavirus (HPV) DNA test positive (R87.820)
          R87.610 Atypical squamous cells of undetermined significance on cytologic smear of cervix (ASC-US)
          R87.611 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of cervix (ASC-H)
          R87.612 Low grade squamous intraepithelial lesion on cytologic smear of cervix (LGSIL)
          R87.613 High grade squamous intraepithelial lesion on cytologic smear of cervix (HGSIL)
          R87.614 Cytologic evidence of malignancy on smear of cervix
          R87.615 Unsatisfactory cytologic smear of cervix
             Inadequate sample of cytologic smear of cervix
          R87.616 Satisfactory cervical smear but lacking transformation zone
          R87.618 Other abnormal cytological findings on specimens from cervix uteri
          R87.619 Unspecified abnormal cytological findings in specimens from cervix uteri
             Abnormal cervical cytology NOS
             Abnormal Papanicolaou smear of cervix NOS
             Abnormal thin preparation smear of cervix NOS
             Atypical endocervial cells of cervix NOS
             Atypical ​endometrial cells of cervix NOS
             Atypical glandular cells of cervix NOS
       R87.62 Abnormal cytological findings in specimens from vagina
          Use additional code to identify acquired absence of uterus and cervix, if applicable (Z90.71-)
          Excludes1: abnormal cytological findings in specimens from cervix uteri (R87.61-)
             abnormal cytological findings in specimens from other female genital organs (R87.69)
             carcinoma in situ of vagina (histologically confirmed) (D07.2)
             vaginal intraepithelial neoplasia I [VAIN I] (N89.0)
             vaginal intraepithelial neoplasia II [VAIN II] (N89.1)
             vaginal intraepithelial neoplasia III [VAIN III] (D07.2)
             dysplasia (mild) (moderate) of vagina (histologically confirmed) (N89.-)
             severe dysplasia of vagina (histologically confirmed) (D07.2)
          Excludes2: vaginal high risk human papillomavirus (HPV) DNA test positive (R87.811)
             vaginal low risk human papillomavirus (HPV) DNA test positive (R87.821)
          R87.620 Atypical squamous cells of undetermined significance on cytologic smear of vagina (ASC-US)
          R87.621 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H)
          R87.622 Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)
          R87.623 High grade squamous intraepithelial lesion on cytologic smear of vagina (HGSIL)
          R87.624 Cytologic evidence of malignancy on smear of vagina
          R87.625 Unsatisfactory cytologic smear of vagina
             Inadequate sample of cytologic smear of vagina
          R87.628 Other abnormal cytological findings on specimens from vagina
          R87.629 Unspecified abnormal cytological findings in specimens from vagina
             Abnormal Papanicolaou smear of vagina NOS
             Abnormal thin preparation smear of vagina NOS
             Abnormal vaginal cytology NOS
             Atypical ​endocervical cells of vagina NOS
             Atypical endometrial cells of vagina NOS
             Atypical glandular cells of vagina NOS
       R87.69 Abnormal cytological findings in specimens from other female genital organs
             Abnormal cytological findings in specimens from female genital organs NOS
             Excludes1: dysplasia of vulva (histologically confirmed) (N90.0-N90.3)
    R87.7 Abnormal histological findings in specimens from female genital organs
       Excludes1: carcinoma in situ (histologically confirmed) of female genital organs (D06-D07.3)
          cervical intraepithelial neoplasia I [CIN I] (N87.0)
          cervical intraepithelial neoplasia II [CIN II] (N87.1)
          cervical intraepithelial neoplasia III [CIN III] (D06.-)
          dysplasia (mild) (moderate) of cervix uteri (histologically confirmed) (N87.-)
          dysplasia (mild) (moderate) of vagina (histologically confirmed) (N89.-)
          vaginal intraepithelial neoplasia I [VAIN I] (N89.0)
          vaginal intraepithelial neoplasia II [VAIN II] (N89.1)
          vaginal intraepithelial neoplasia III [VAIN III] (D07.2)
          severe dysplasia of cervix uteri (histologically confirmed) (D06.-)
          severe dysplasia of vagina (histologically confirmed) (D07.2)
    R87.8 Other abnormal findings in specimens from female genital organs
       R87.81 High risk human papillomavirus (HPV) DNA test positive from female genital organs
          Excludes1: anogenital warts due to human papillomavirus (HPV) (A63.0)
             condyloma acuminatum (A63.0)
          R87.810 Cervical high risk human papillomavirus (HPV) DNA test positive
          R87.811 Vaginal high risk human papillomavirus (HPV) DNA test positive
       R87.82 Low risk human papillomavirus (HPV) DNA test positive from female genital organs
          Use additional code for associated human papillomavirus (B97.7)
          R87.820 Cervical low risk human papillomavirus (HPV) DNA test positive
          R87.821 Vaginal low risk human papillomavirus (HPV) DNA test positive
       R87. ​89 Other abnormal findings in specimens from female genital organs
          Abnormal chromosomal findings in specimens from female genital organs
    R87.9 Unspecified abnormal finding in specimens from female genital organs

## R88 Abnormal findings in other body fluids and substancesR88 Abnormal findings in other body fluids and substances

    R88.0 Cloudy (hemodialysis) (peritoneal) dialysis effluent
    R88.8 Abnormal findings in other body fluids and substances

## R89 Abnormal findings in specimens from other organs, systems and tissuesR89 Abnormal findings in specimens from other organs, systems and tissues

    Includes: abnormal findings in nipple discharge
       abnormal findings in synovial fluid
       abnormal findings in wound secretions
    R89.0 Abnormal level of enzymes in specimens from other organs, systems and tissues
    R89.1 Abnormal level of hormones in specimens from other organs, systems and tissues
    R89.2 Abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues
    R89.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from other organs, systems and tissues
    R89.4 Abnormal immunological findings in specimens from other organs, systems and tissues
    R89.5 Abnormal microbiological findings in specimens from other organs, systems and tissues
       Positive culture findings in specimens from other organs, systems and tissues
       Excludes1: colonization status (Z22.-)
    R89.6 Abnormal cytological findings in specimens from other organs, systems and tissues
    R89.7 Abnormal histological findings in specimens from other organs, systems and tissues
    R89.8 Other abnormal findings in specimens from other organs, systems and tissues
       Abnormal chromosomal findings in specimens from other organs, systems and tissues
    R89.9 Unspecified abnormal finding in specimens from other organs, systems and tissues

# Abnormal ​findings on diagnostic imaging and in function studies, without diagnosis (R90-R94)

    Includes: nonspecific abnormal findings on diagnostic imaging by:
       computerized axial tomography [CAT scan]
       magnetic resonance imaging [MRI][NMR]
       positron emission tomography [PET scan]
       thermography
       ultrasound [echogram]
       X-ray examination
    Excludes1: abnormal findings on antenatal screening of mother (O28.-)
       diagnostic abnormal findings classified elsewhere - see Alphabetical Index

## R90 Abnormal findings on diagnostic imaging of central nervous systemR90 Abnormal findings on diagnostic imaging of central nervous system

    R90.0 Intracranial space-occupying lesion found on diagnostic imaging of central nervous system
    R90.8 Other abnormal findings on diagnostic imaging of central nervous system
       R90.81 Abnormal echoencephalogram
       R90.82 White matter disease, unspecified
       R90.89 Other abnormal findings on diagnostic imaging of central nervous system
          Other cerebrovascular abnormality found on diagnostic imaging of central nervous system

## R91 Abnormal findings on diagnostic imaging of lungR91 Abnormal findings on diagnostic imaging of lung

    Includes: coin lesion NOS found on diagnostic imaging of lung
       lung mass NOS found on diagnostic imaging of lung

## R92 Abnormal and inconclusive findings on diagnostic imaging of breastR92 Abnormal and inconclusive findings on diagnostic imaging of breast

    R92.0 Mammographic microcalcification found on diagnostic imaging of breast
       Excludes2: mammographic calcification (calculus) found on diagnostic imaging of breast (R92.1)
    R92.1 Mammographic calcification found on diagnostic imaging of breast
       Mammographic calculus found on diagnostic imaging of breast
    R92.2 Inconclusive mammogram
       Dense breasts NOS
       Inconclusive mammogram NEC
       Inconclusive mammography due to dense breasts
       Inconclusive mammography NEC
    R92. ​8 Other abnormal and inconclusive findings on diagnostic imaging of breast

## R93 Abnormal findings on diagnostic imaging of other body structuresR93 Abnormal findings on diagnostic imaging of other body structures

    R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
       Excludes1: intracranial space-occupying lesion found on diagnostic imaging (R90.0)
    R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
       Abnormal echocardiogram NOS
       Abnormal heart shadow
    R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
       Nonvisualization of gallbladder
    R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
    R93.4 Abnormal findings on diagnostic imaging of urinary organs
       Filling defect of bladder found on diagnostic imaging
       Filling defect of kidney found on diagnostic imaging
       Filling defect of ureter found on diagnostic imaging
       Excludes1: hypertrophy of kidney (N28.81)
    R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
    R93.6 Abnormal findings on diagnostic imaging of limbs
       Excludes2: abnormal finding in skin and subcutaneous tissue (R93.8)
    R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
       Excludes2: abnormal findings on diagnostic imaging of skull (R93.0)
    R93.8 Abnormal findings on diagnostic imaging of other specified body structures
       Abnormal finding by radioisotope localization of placenta
       Abnormal radiological finding in skin and subcutaneous tissue
       Mediastinal shift
    R93.9 Diagnostic imaging inconclusive due to excess body fat of patient

## R94 Abnormal results of function studiesR94 Abnormal results of function studies

    Includes: abnormal results of radionuclide [radioisotope] uptake studies
       abnormal results of scintigraphy
    R94.0 Abnormal results of function studies of central nervous system
       R94.01 Abnormal electroencephalogram [EEG]
       R94.02 Abnormal brain scan
       R94.09 Abnormal results of other function studies of central nervous system
    R94. ​1 Abnormal results of function studies of peripheral nervous system and special senses
       R94.11 Abnormal results of function studies of eye
          R94.110 Abnormal electro-oculogram [EOG]
          R94.111 Abnormal electroretinogram [ERG]
             Abnormal retinal function study
          R94.112 Abnormal visually evoked potential [VEP]
          R94.113 Abnormal oculomotor study
          R94.118 Abnormal results of other function studies of eye
       R94.12 Abnormal results of function studies of ear and other special senses
          R94.120 Abnormal auditory function study
          R94.121 Abnormal vestibular function study
          R94.128 Abnormal results of other function studies of ear and other special senses
       R94.13 Abnormal results of function studies of peripheral nervous system
          R94.130 Abnormal response to nerve stimulation, unspecified
          R94.131 Abnormal electromyogram [EMG]
             Excludes1: electromyogram of eye (R94.113)
          R94.138 Abnormal results of other function studies of peripheral nervous system
    R94.2 Abnormal results of pulmonary function studies
       Reduced ventilatory capacity
       Reduced vital capacity
    R94.3 Abnormal results of cardiovascular function studies
       R94.30 Abnormal result of cardiovascular function study, unspecified
       R94.31 Abnormal electrocardiogram [ECG] [EKG]
          Excludes1: long QT syndrome (I45.81)
       R94.39 Abnormal result of other cardiovascular function study
          Abnormal electrophysiological intracardiac studies
          Abnormal phonocardiogram
          Abnormal vectorcardiogram
    R94.4 Abnormal results of kidney function studies
       Abnormal renal function test
    R94.5 Abnormal results of liver function studies
    R94.6 Abnormal results of thyroid function studies
    R94.7 Abnormal results of other endocrine function studies
       Excludes2: abnormal glucose (R73.0-)
    R94.8 Abnormal results of function studies of other organs and systems
       Abnormal basal metabolic rate [BMR]
       Abnormal ​bladder function test
       Abnormal splenic function test

# Abnormal tumor markers (R97)Abnormal tumor markers (R97)
## R97 Abnormal tumor markersR97 Abnormal tumor markers

    Elevated tumor associated antigens [TAA]
    Elevated tumor specific antigens [TSA]
    R97.0 Elevated carcinoembryonic antigen [CEA]
    R97.1 Elevated cancer antigen 125 [CA 125]
    R97.2 Elevated prostate specific antigen [PSA]
    R97.8 Other abnormal tumor markers

# Ill-defined and unknown cause of mortality (R99)Ill-defined and unknown cause of mortality (R99)
## R99 Ill-defined and unknown cause of mortalityR99 Ill-defined and unknown cause of mortality

    Includes: Death (unexplained) NOS
       Unspecified cause ofmortality