# NIOSH Manual of Analytical Methods
## Chapters

* Chapter A: Purpose and Scope
* Chapter B: How to Use NMAM
* Chapter C: Quality Assurance
* Chapter D: General Considerations for Sampling Airborne Contaminants
* Chapter E: Development and Evaluation of Methods
* Chapter F: Application of Biological Monitoring Methods
* Chapter G: Aerosol Photometers for Respirable Dust Measurements
* Chapter H: Portable Electrochemical Sensor Methods
* Chapter I: Portable Gas Chromatography
* Chapter J: Sampling and Characterization of Bioaerosols
* Chapter K: Determination of Airborne Isocyanate Exposure
* Chapter L: Measurement of Fibers
* Chapter M: Sampling and Analysis of Soluble Metal Compounds
* Chapter N: Aerosol Sampling: Minimizing Particle Loss from Cassette Bypass Leakage
* Chapter O: Factors Affecting Aerosol Sampling
* Chapter P: Measurement Uncertainty and NIOSH Method Accuracy Range
* Chapter Q: Monitoring of Diesel Particulate Exhaust in the Workplace
* Chapter R: Determination of Airborne Crystalline Silica
* Glossary: Glossary of Abbreviations, Definitions, and Symbols

## Methods

| No. | | Method description |
| 0500 | … | Particulates Not Otherwise Regulated, Total |
| 0501 | … | Particulates Not Otherwise Regulated, Total |
| 0600 | … | Particulates Not Otherwise Regulated, Respirable |
| 0800 | … | Bioaerosol Sampling (Indoor Air) |
| 0801 | … | Aerobic Bacteria by GC-FAME |
| 0900 | … | Mycobacterium Tuberculosis, Airborne |
| 1000 | … | Allyl Chloride |
| 1001 | … | Methyl Chloride |
| 1002 | … | β-Chloroprene |
| 1003 | … | Hydrocarbons, Halogenated |
| 1004 | … | Dichloroethyl Ether |
| 1005 | … | Methylene Chloride |
| 1006 | … | Fluorotrichloromethane |
| 1007 | … | Vinyl Chloride |
| 1008 | … | Ethylene Dibromide |
| 1009 | … | Vinyl Bromide |
| 1010 | … | Epichlorohydrin |
| 1011 | … | Ethyl Bromide |
| 1012 | … | Difluorodibromomethane |
| 1013 | … | Propylene Dichloride |
| 1014 | … | Methyl Iodide |
| 1015 | … | Vinylidene Chloride |
| 1016 | … | 1,1,1,2-Tetrachloro-2,2-Difluoroethane and 1,1,2,2-Tetrachloro-1,2-Difluoroethane |
| 1017 | … | Trifluorobromomethane |
| 1018 | … | Chlorodifluoromethane |
| 1018 | … | Dichlorodifluoromethane |
| 1018 | … | 1,2-Dichlorotetrafluoroethane (1018) |
| 1019 | … | 1,1,2,2-Tetrachloroethane |
| 1020 | … | 1,1,2-Trichloro-1,2,2-Trifluoroethane |
| 1022 | … | Trichloroethylene |
| 1024 | … | 1,3-Butadiene |
| 1025 | … | 1- and 2-Bromopropane |
| 1026 | … | p-Chlorobenzotrifluoride |
| 1300 | … | Ketones I |
| 1301 | … | Ketones II |
| 1302 | … | n-Methyl-2-Pyrrolidinon |
| 1400 | … | Alcohols I |
| 1401 | … | Alcohols II |
| 1402 | … | Alcohols III |
| 1403 | … | Alcohols IV |
| 1404 | … | Methylcyclohexanol |
| 1405 | … | Alcohols Combined |
| 1450 | … | Esters 1 |
| 1451 | … | Methyl Cellosolve Acetate |
| 1452 | … | Ethyl Formate |
| 1453 | … | Vinyl Acetate |
| 1454 | … | Isopropyl Acetate |
| 1457 | … | Ethyl Acetate |
| 1458 | … | Methyl Acetate |
| 1459 | … | Methyl Acrylate |
| 1460 | … | Isopropyl Acetate |
| 1500 | … | Hydrocarbons, BP 36° - 216 °C |
| 1501 | … | Hydrocarbons, Aromatic |
| 1550 | … | Naphthas |
| 1551 | … | 1551 |
| 1552 | … | Terpenes |
| 1600 | … | Carbon Disulfide |
| 1601 | … | 1,1-Dichloro-1-Nitroethane |
| 1602 | … | Dioxane |
| 1603 | … | Acetic Acid |
| 1604 | … | Acrylonitrile |
| 1606 | … | Acetonitrile |
| 1608 | … | Glycidol |
| 1609 | … | Tetrahydrofuran |
| 1610 | … | Ethyl Ether |
| 1611 | … | Methylal |
| 1612 | … | Propylene Oxide |
| 1613 | … | Pyridine |
| 1614 | … | Ethylene Oxide |
| 1615 | … | Methyl tert-Butyl Ether |
| 1616 | … | n-Butyl Glycidyl Ether |
| 1617 | … | Phenyl Ether |
| 1618 | … | Isopropyl Ether |
| 1619 | … | Phenyl Glycidyl Ether |
| 1620 | … | Isopropyl Glycidyl Ether |
| 2000 | … | Methanol |
| 2002 | … | Amines, Aromatic |
| 2003 | … | 1,1,2,2-Tetrabromoethane |
| 2004 | … | Dimethylacetamide |
| 2005 | … | Nitroaromatic Compounds |
| 2007 | … | Aminoethanol Compounds I |
| 2008 | … | Chloroacetic Acid |
| 2010 | … | Amines, Aliphatic |
| 2011 | … | Formic Acid |
| 2012 | … | n-Butylamine |
| 2013 | … | Phenyl Ether–Diphenyl Mixture (2013) |
| 2014 | … | p-Chlorophenol |
| 2015 | … | Chloroacetaldehyde |
| 2016 | … | Formaldehyde |
| 2017 | … | Aniline, o-Toluidine, and Nitrobenzene |
| 2018 | … | Aliphatic Aldehydes |
| 2500 | … | Methyl Ethyl Ketone |
| 2501 | … | Acrolein |
| 2503 | … | Mevinphos |
| 2504 | … | Tetraethyl Pyrophosphate |
| 2505 | … | Furfuryl Alcohol |
| 2506 | … | Acetone Cyanohydrin |
| 2507 | … | Ethylene Glycol Dinitrate |
| 2507 | … | Nitroglycerin |
| 2508 | … | Isophorone |
| 2510 | … | 1-Octanethiol |
| 2513 | … | Ethylene Chlorohydrin |
| 2514 | … | Anisidine |
| 2515 | … | Diazomethane |
| 2516 | … | Dichlorofluoromethane |
| 2517 | … | Pentachloroethane |
| 2518 | … | Hexachloro-1,3-cyclopentadiene |
| 2519 | … | Ethyl Chloride |
| 2520 | … | Methyl Bromide |
| 2521 | … | Methylcyclohexanone |
| 2522 | … | Nitrosamines |
| 2523 | … | 1,3-Cyclopentadiene |
| 2524 | … | Dimethyl Sulfate |
| 2525 | … | n-Butyl Mercaptan |
| 2526 | … | Nitroethane |
| 2527 | … | Nitromethane |
| 2528 | … | 2-Nitropropane |
| 2529 | … | Furfural |
| 2530 | … | Diphenyl |
| 2531 | … | Glutaraldehyde |
| 2532 | … | Glutaraldehyde |
| 2533 | … | Tetraethyl Lead |
| 2534 | … | Tetramethyl Lead |
| 2535 | … | Toluene-2,4-diisocyanate |
| 2536 | … | Valeraldehyde |
| 2537 | … | Methyl and Ethyl Methacrylate |
| 2538 | … | Acetaldehyde by GC |
| 2539 | … | Aldehydes, Screening |
| 2540 | … | Triethylenetetramine |
| 2540 | … | Ethylenediamine |
| 2540 | … | Diethylenetriamine |
| 2541 | … | Formaldehyde by GC |
| 2542 | … | Mercaptans, Methyl-, Ethyl-, and n-Butyl- |
| 2543 | … | Hexachlorobutadiene |
| 2544 | … | Nicotine |
| 2545 | … | Allyl Glycidyl Ether |
| 2546 | … | Cresol (All Isomers) and Phenol |
| 2549 | … | Volatile Organic Compounds (Screening) |
| 2550 | … | Benzothiazole in Asphalt Fume |
| 2551 | … | Nicotine |
| 2552 | … | Methyl Acrylate |
| 2553 | … | Ketones II |
| 2554 | … | Glycol Ethers |
| 2555 | … | Ketones I |
| 2556 | … | Isophorone |
| 2557 | … | Diacetyl |
| 2558 | … | Acetoin |
| 2559 | … | Decabromodiphenyl Oxide |
| 2560 | … | 1-Nitropyrene in Diesel Particulates |
| 2561 | … | 2-(Dimethylamino)ethanol and 1-Dimethylamino-2-propanol |
| 2562 | … | 1,1,2,2-Tetrachloroethane |
| 3500 | … | Formaldehyde by VIS |
| 3502 | … | Phenol |
| 3503 | … | Hydrazine |
| 3505 | … | Tetramethyl Thiourea |
| 3506 | … | Acetic Anhydride |
| 3507 | … | Acetaldehyde |
| 3507 | … | Acetaldehyde by HPLC |
| 3508 | … | Methyl Ethyl Ketone Peroxide |
| 3509 | … | Aminoethanol Compounds II |
| 3510 | … | Monomethylhydrazine |
| 3511 | … | Monomethylaniline |
| 3512 | … | Maleic Anhydride |
| 3513 | … | Tetranitromethane |
| 3514 | … | Ethylenimine |
| 3515 | … | 1,1-Dimethylhydrazine |
| 3516 | … | Crotonaldehyde |
| 3518 | … | Phenylhydrazine |
| 3600 | … | Maneb Dermal Patch |
| 3601 | … | Maneb Hand Wash |
| 3700 | … | Benzene by Portable GC |
| 3701 | … | Trichloroethylene by Portable GC |
| 3702 | … | Ethylene Oxide by Portable GC |
| 3704 | … | Perchloroethylene (Portable GC) in Exhaled Breath and Air |
| 3800 | … | Organic and Inorganic Gases by Extractive FTIR Spectrometry |
| 4000 | … | Toluene (Diffusive Sampler) |
| 5000 | … | Carbon Black |
| 5001 | … | 2,4-D |
| 5001 | … | 2,4,5-T |
| 5002 | … | Warfarin |
| 5003 | … | Paraquat |
| 5004 | … | Hydroquinone |
| 5005 | … | Thiram |
| 5006 | … | Carbaryl |
| 5007 | … | Rotenone |
| 5008 | … | Pyrethrum |
| 5009 | … | Benzoyl Peroxide |
| 5010 | … | Bromoxynil and Bromoxynil Octanoate |
| 5011 | … | Ethylene Thiourea |
| 5012 | … | EPN |
| 5013 | … | Dyes, Benzidine-, o-Tolidine-, o-Dianisidine- |
| 5014 | … | Chlorinated Terphenyl (60% Chlorine) |
| 5016 | … | Strychnine |
| 5017 | … | Dibutyl Phosphate |
| 5018 | … | 2,4,7-Trinitrofluoren-9-one |
| 5019 | … | Azelaic Acid |
| 5020 | … | Di(2-ethylhexyl) Phthalate |
| 5020 | … | Di(2-ethylhexyl) Phthalate (Partial Evaluation) |
| 5021 | … | o-Terphenyl |
| 5022 | … | Arsenic, Organo- |
| 5023 | … | Coal Tar Pitch Volatiles |
| 5025 | … | Chlorinated Diphenyl Oxide |
| 5026 | … | Oil Mist, Mineral |
| 5027 | … | Ribavirin |
| 5029 | … | 4,4'-Methylenedianiline |
| 5030 | … | Cyanuric Acid |
| 5031 | … | Aspartame |
| 5032 | … | Pentamidine Isethionate |
| 5033 | … | p-Nitroaniline |
| 5034 | … | Tributyl Phosphate |
| 5035 | … | Super Absorbent Polymers |
| 5036 | … | Trimellitic Anhydride |
| 5037 | … | Triorthocresyl Phosphate |
| 5038 | … | Triphenyl Phosphate |
| 5039 | … | Chlorinated Camphene |
| 5040 | … | Diesel Particulate Matter (as Elemental Carbon) |
| 5041 | … | Capsaicin and Dihydrocapsaicin |
| 5042 | … | Benzene-Soluble Fraction and Total Particulate (Asphalt Fume) |
| 5043 | … | p-Toluenesulfonic Acid |
| 5044 | … | Estrogenic Compounds |
| 5046 | … | Tetrakis(hydroxymethyl)phosphonium Chloride |
| 5100 | … | Carbon Black |
| 5500 | … | Ethylene Glycol |
| 5502 | … | Aldrin |
| 5502 | … | Lindane |
| 5503 | … | Polychlorobiphenyls |
| 5504 | … | Organotin Compounds (as Sn) |
| 5506 | … | Polynuclear Aromatic Hydrocarbons by HPLC |
| 5508 | … | Kepone |
| 5509 | … | Benzidine |
| 5510 | … | Chlordane |
| 5512 | … | Pentachlorophenol |
| 5514 | … | Demeton |
| 5515 | … | Polynuclear Aromatic Hydrocarbons by GC |
| 5516 | … | 2,4- and 2,6-Toluenediamine (in the presence of isocyanates) |
| 5517 | … | Polychlorobenzenes |
| 5518 | … | Naphthylamines, α and β |
| 5519 | … | Endrin |
| 5521 | … | Isocyanates, Monomeric |
| 5522 | … | Isocyanate |
| 5523 | … | Glycols |
| 5524 | … | Metalworking Fluids (MWF) All Categories |
| 5525 | … | Isocyanates, Total (MAP) |
| 5526 | … | Methyltin Chlorides |
| 5527 | … | Triphenyl Tin Chloride (as Sn) |
| 5600 | … | Organophosphorus Pesticides |
| 5601 | … | Organonitrogen Pesticides |
| 5602 | … | Chlorinated and Organonitrogen Herbicides (Air Sampling) |
| 5603 | … | Alachlor in Air |
| 5606 | … | Thiphanate-Methyl in Air |
| 5700 | … | Formaldehyde on Dust (Textile or Wood) |
| 5701 | … | Resorcinol (5701) |
| 5800 | … | Polycyclic Aromatic Compounds, Total (PACs) |
| 6001 | … | Arsine |
| 6002 | … | Phosphine |
| 6004 | … | Sulfur Dioxide |
| 6005 | … | Iodone |
| 6006 | … | Diborane |
| 6007 | … | Nickel Carbonyl |
| 6008 | … | Stibine |
| 6009 | … | Mercury |
| 6010 | … | Hydrogen Cyanide |
| 6011 | … | Bromine |
| 6012 | … | Sulfuryl Fluoride |
| 6013 | … | Hydrogen Sulfide |
| 6014 | … | Nitric Oxide and Nitrogen Oxide |
| 6015 | … | Ammonia |
| 6016 | … | Ammonia by IC |
| 6017 | … | Hydrogen Cyanide |
| 6402 | … | Phosphorus Trichloride |
| 6600 | … | Nitrous Oxide |
| 6601 | … | Oxygen |
| 6602 | … | Sulfur Hexafluoride by Portable GC |
| 6603 | … | Carbon Dioxide |
| 6604 | … | Carbon Monoxide |
| 6700 | … | Nitrogen Dioxide (Diffusive Sampler) |
| 7013 | … | Aluminum and Compounds, as Al |
| 7020 | … | Calcium and Compounds, as Ca |
| 7024 | … | Chromium and Compounds, as Cr |
| 7027 | … | Cobalt and Compounds, as Co |
| 7029 | … | Copper (Dust and Fume) |
| 7030 | … | Zinc and Compounds, as Zn |
| 7048 | … | Cadmium and Compounds, as Cd |
| 7056 | … | Barium, Soluble Compounds |
| 7074 | … | Tungsten (Soluble and Insoluble) |
| 7082 | … | Lead by Flame AAS |
| 7102 | … | Beryllium and Compounds, as Be |
| 7015 | … | Lead by GFAAS |
| 7300 | … | Elements by ICP |
| 7301 | … | Elements by ICP (Aqua Regia Ashing) |
| 7302 | … | Elements by ICP (Microwave Digestion) |
| 7303 | … | Elements by ICP (Hot Block/HCl/HNO3 Digestion) |
| 7304 | … | Elements by ICP (Microwave Digestion) |
| 7306 | … | Elements by Cellulosic Internal Capsule Sampler |
| 7400 | … | Asbestos and Other Fibers by PCM |
| 7401 | … | Alkaline Dusts |
| 7402 | … | Asbestos by TEM |
| 7404 | … | Cellulose Insulation |
| 7500 | … | Silica, Crystalline, by XRD (Filter Redeposition) |
| 7501 | … | Silica, Amorphous |
| 7502 | … | Zinc Oxide |
| 7504 | … | Vanadium Oxides |
| 7505 | … | Lead Sulfide |
| 7506 | … | Boron Carbide |
| 7600 | … | Chromium, Hexavalent |
| 7601 | … | Silica, Crystalline, by VIS |
| 7602 | … | Silica, Crystalline by IR (KBr pellet) |
| 7603 | … | Quartz in Coal Mine Dust, by IR (Redeposition) |
| 7605 | … | Chromium, Hexavalent by Ion Chromatography |
| 7701 | … | Lead by Portable Ultrasonic Extraction/ASV |
| 7702 | … | Lead by Field Portable XRF |
| 7703 | … | Chromium, Hexavalent, by Field-Portable Spectrophotometry |
| 7704 | … | Beryllium in Air by Field-Portable Fluorometry |
| 7900 | … | Arsenic and Compounds, as As |
| 7901 | … | Arsenic Trioxide, as As |
| 7902 | … | Fluorides, Aerosol and Gas by ISE |
| 7903 | … | Acids, Inorganic |
| 7904 | … | Cyanides, Aerosol and Gas |
| 7905 | … | Phosphorus |
| 7906 | … | Particulate Fluorides and Hydrofluoric Acid by Ion Chromatography |
| 7907 | … | Volatile Acids by Ion Chromatography |
| 7908 | … | Non-Volatile Acids (Sulfuric Acid and Phosphoric Acid) |
| 8001 | … | Pentachlorophenol in Blood |
| 8002 | … | Methyl Ethyl Ketone, Ethanol, and Toluene in Blood |
| 8003 | … | Lead in Blood and Urine |
| 8004 | … | Polychlorobiphenyls in Serum |
| 8005 | … | Elements in Blood or Tissue |
| 8007 | … | Toluene in Blood |
| 8300 | … | Hippuric Acid in Urine |
| 8301 | … | Hippuric and Methyl Hippuric Acids in Urine |
| 8302 | … | MBOCA in Urine |
| 8303 | … | Pentachlorophenol in Urine |
| 8304 | … | Benzidine in Urine (Screening Test) |
| 8305 | … | Phenol and p-Cresol in Urine |
| 8306 | … | Benzidine in Urine |
| 8308 | … | Fluoride in Urine |
| 8310 | … | Metals in Urine |
| 8315 | … | Triazine Herbicides and Their Metabolites in Urine |
| 8316 | … | Butoxyacetic Acid in Urine |
| 8317 | … | Aniline and o-Toludine in Urine |
| 8319 | … | Acetone and Methyl Ethyl Ketone in Urine |
| 8322 | … | Trichloroacetic Acid in Urine |
| 8324 | … | 3-Bromopropionic Acid in Urine |
| 8326 | … | s-Benzylmercapturic Acid and s-Phenylmercapturic Acid in Urine |
| 9000 | … | Asbestos, Chrysotile by XRD |
| 9002 | … | Asbestos (Bulk) by PLM |
| 9100 | … | Lead in Surface Wipe Samples |
| 9101 | … | Chromium, Hexavalent, in Settled Dust Samples |
| 9102 | … | Elements on Wipes |
| 9105 | … | Lead in Dust Wipes by Chemical Spot Test |
| 9106 | … | Methamphetamine and Illicit Drugs, Precursors and Adulterants on Wipes by Liquid-Liquid Extraction |
| 9109 | … | Methamphetamine and Illicit Drugs, Precursors, and Adulterants on Wipes by Solid Phase Extraction |
| 9110 | … | Beryllium in Surface Wipes by Field-Portable Fluorometry |
| 9111 | … | Metamphetamine on Wipes by Liquid Chromatography/Mass Spectrometry |
| 9200 | … | Chlorinated and Organonitrogen Herbicides (Hand Wash) |
| 9201 | … | Chlorinated and Organonitrogen Herbicides (Patch) |
| 9202 | … | Captan and Thiphanate-Methyl in Handrinse |
| 9205 | … | Captan and Thiophanate-Methyl on Dermal Patch |
This work is a work of the National Institute for Occupational Safety and Health, part of the Centers for Disease Control and Prevention in the United States Department of Health and Human Services, taken or made as part of an employee's official duties. As a work of the U.S. federal government, it is in the public domain.
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