# Radiation Oncology/Breast/Guidelines

* Front Page: Radiation Oncology | RTOG Trials
* Breast: Main Page |
* Staging |
* Breast Overview |
* Prevention |
* Benign |
* DCIS |
* LCIS |
* Paget's |
* Phyllodes tumor |
* Early stage |
* Advanced stage |
* Post mastectomy |
* Inflammatory |
* Partial breast irradiation |
* Regional lymphatics |
* Hormonal therapy |
* Chemotherapy |
* RT technique |
* Recurrence |
* Toxicity of RT |
* Randomized |
* NSABP trials
Breast Cancer Official Guidelines

## Screening topics

Screening
* ACS: Breast Cancer: Early Detection
** Guideline link

## Testing / Workup topics

Tumor Markers
* ASCO: Tumor markers in breast cancer
** 2007 Guideline link PMID 17954709 -- "American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer." (Harris L, J Clin Oncol. 2007 Nov 20;25(33):5287-312.)
** The above showed values of CA125,CEA,ER/PR and Her2
HER2 testing
* ASCO:
** 2013 Guideline link PMID 24101045 -- "Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update" (Wolff AC, J Clin Oncol. 2013 Oct 7 [Epub ahead of print])

## Clinical / treatment topics

DCIS
* ACR: Appropriateness Criteria
** Ductal Carcinoma In Situ
* SSO / ASTRO: Margin width
** 2016 -- "Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma in Situ."
*** PMID 27538810 (Pract Radiat Oncol.), or PMID 27528719 (J Clin Oncol), or 27527714 (Ann Surg Oncol)
Sentinel Lymph Node
* ASCO:
** 2014 PMID 24663048 -- "Sentinel Lymph Node Biopsy for Patients With Early-Stage Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update" (Lyman GH, J Clin Oncol. 2014 Mar 24. [Epub ahead of print])
Margins
* SSO / ASTRO: Margin width (invasive carcinoma)
** 2014 -- "Society of Surgical Oncology–American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer"
*** PMID 24516019 Abstract (Moran MS, J Clin Oncol. 2014 Feb 10. [Epub ahead of print])
*** PMID 24521674 (Moran MS, Int J Radiat Oncol Biol Phys. 2014 Mar 1;88(3):553-64.)
*** PMID 24711553 (Buchholz TA, J Clin Oncol. 2014 Apr 7. [Epub ahead of print]) - ASCO endorsement of SSO/ASTRO guideline.
* SSO / ASTRO / ASCO: Margin width (DCIS)
** 2016 -- "Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma in Situ."
*** PMID 27538810 (Morrow M, Pract Radiat Oncol. 2016 Sep-Oct;6(5):287-95.)
*** PMID 27528719 (Morrow M, J Clin Oncol. 2016 Aug 15.[Epub ahead of print])
*** PMID 27527714 (Morrow M, Ann Surg Oncol. 2016 Nov;23(12):3801-3810.)
Breast Conservation
* ASTRO: Whole Breast Fractionation
** 2010 PMID 20638191 -- "Fractionation for Whole Breast Irradiation: An American Society for Radiation Oncology (ASTRO) Evidence-Based Guideline." (Smith BD, Int J Radiat Oncol Biol Phys. 2010 Jul 15. [Epub ahead of print])
* DEGRO: Breast Conserving Therapy
** 2007 PMID 18040609 -- "DEGRO practical guidelines for radiotherapy of breast cancer I: breast-conserving therapy." (Sautter-Bihl ML, Strahlenther Onkol. 2007 Dec;183(12):661-6.)
* ACR: Appropriateness Criteria
** Conservative Surgery and Radiation - Stage I and II
Accelerated Partial Breast Irradiation
* GEC-ESTRO: APBI Recommendations
** 2010 PMID 20181402 -- "Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: Recommendations of the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009)." (Polgar C, Radiother Oncol. 2010 Mar;94(3):264-273. Epub 2010 Feb 22.)
* ASTRO: APBI Consensus Statement
** 2009 PMID 19545784 -- "Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO)." (Smith BD, Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):987-1001.)
* ABS: APBI Guideline
** 2007 Guideline link
* ASBS: APBI Consensus Statement
** Guideline link
Postmastectomy Radiation
* DEGRO: Postmastectomy RT, regional lymphatics, and locally advanced disease
** 2008 PMID 19016032 -- "DEGRO practical guidelines for radiotherapy of breast cancer II. Postmastectomy radiotherapy, irradiation of regional lymphatics, and treatment of locally advanced disease." (Sautter-Bihl ML, Strahlenther Onkol. 2008 Jul;184(7):347-53.)
* ASCO: Clinical Practice Guideline
** 2001 PMID 11230499 -- "Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology." (Recht A, J Clin Oncol. 2001 Mar 1;19(5):1539-69.)
* ASTRO: PMRT Consensus Statement
** 1999 PMID 10421530 -- "Consensus Statement on postmastectomy radiation therapy." (Harris JR, Int J Radiat Oncol Biol Phys. 1999 Jul 15;44(5):989-90.)
* ACR: ACR Appropriateness Criteria
** Postmastectomy Radiotherapy
* ASCO / ASTRO / SSO: Guideline update
** 2016 PMID 27659727 (Pract Radiat Oncol), PMID 27646947 (JCO), PMID 27646018 (Ann Surg Oncol) -- "Postmastectomy Radiotherapy: An ASCO, ASTRO, SSO Focused Guideline Update." (Recht A)
Locally Advanced Breast Cancer
* ACR: ACR Appropriateness Criteria
** Locally Advanced Breast Cancer
Recurrence
* ACR: Appropriatness Critiera
** Local-Regional Recurrence and Salvage Surgery
RT in Metastatic Disease
* DEGRO: Brain Metastases and Leptomeningeal Carcinomatosis
** 2010 PMID 20127222 -- "DEGRO Practical Guidelines for Palliative Radiotherapy of Breast Cancer Patients: Brain Metastases and Leptomeningeal Carcinomatosis." (Feyer P, Strahlenther Onkol. 2010 Feb;186(2):63-69. Epub 2010 Jan 26.)
* DEGRO: Bone Metastases and Spinal Cord Compression
** 2009 PMID 19714302 -- "DEGRO practice guidelines for palliative radiotherapy of metastatic breast cancer: bone metastases and metastatic spinal cord compression (MSCC)." (Souchon R, Strahlenther Onkol. 2009 Jul;185(7):417-24. Epub 2009 Aug 28.)
Curative Approach to Metastatic Disease
* ESO-MBC: Can metastatic breast cancer be cured?
** 2010 PMID 20220104 -- "International guidelines for management of metastatic breast cancer: can metastatic breast cancer be cured?" (Pagani O, J Natl Cancer Inst. 2010 Apr 7;102(7):456-63. Epub 2010 Mar 10.)

## Follow-up topics

Follow-up
* ASCO: Breast Cancer Follow-Up and Management After Primary Treatment
** 2012 Guideline link PMID 23129741 -- "Breast Cancer Follow-Up and Management After Primary Treatment: American Society of Clinical Oncology Clinical Practice Guideline Update" (Khatcheressian JL, J Clin Oncol. 2013 Jan 14. -- early release)