# Exercise as it relates to Disease/Effects of yoga on cardiovascular health
## Cardiovascular disease: definition and significance

Cardiovascular disease is defined by a physiological dysfunction in the heart and/or the blood vessels. The following is a list of common cardiovascular diseases:
* coronary heart disease
* cerebrovascular disease
* peripheral arterial disease
* rheumatic heart disease
* congenital heart disease
* deep vein thrombosis and pulmonary embolism
Cardiovascular disease is the leading cause of mortality in the world, taking 17.5 million lives in 2012

## Yoga: definition and benefits

The practice of yoga originated in India and is composed of balance and body weight movements and stretches paired with meditation. It has been used for mind-body engagement for thousands of years. It’s believed that yoga alters the hormonal and sympathetic neuronal pathways in the body to bring a sense of general wellbeing while improving metabolic status and reducing inflammatory action. It has also been suggested that yoga alters the body’s preference for using the parasympathetic nervous system in a way that cardiac vagal reactivity is improved, as well as energy levels and mood.

## Yoga in cardiovascular disease: prevention and treatment

Due to the range of factors that can contribute to the development of cardiovascular disease, many studies have been conducted to determine whether yoga helps with different physiological functions. So far, research has found that it may protect against cardiovascular disease. Specific mechanisms include:
* Improving serum lipid levels
* Decreasing blood pressure, including in type 2 diabetics
* Controlling LDL cholesterol
* Improving parasympathetic activity in heart failure patients
* Regressing atherosclerosis
* Reducing peripheral vascular resistance and blood pressure-rise in response to stress

## Recommendations

As the research on this topic is inconclusive and a dose-response relationship has not been established, at this point there is no prescription for improving cardiovascular health by practicing yoga. Most research settings have been loosely controlled, too small to infer the results or in some cases heavily biased. However, the positive effects that yoga may have on cardiovascular and general health far outweigh the risks of practicing yoga. Perhaps an ideal approach would be to incorporate yoga into a physical activity regime that includes aerobic and resistance training as well as flexibility and meditation.

## Further reading

“Yoga and heart health” by the American Heart Association: http://www.heart.org/HEARTORG/GettingHealthy/PhysicalActivity/Yoga-and-Heart-Health_UCM_434966_Article.jsp
“Yoga: fight stress and find serenity” by Mayo Clinic: http://www.mayoclinic.org/healthy-living/stress-management/in-depth/yoga/art-20044733
“A holistic approach to heart disease” by Yoga Journal: http://www.yogajournal.com/article/health/straight-heart/
“Top 10 ways to reduce your risk of heart disease” by Gaiam Life: http://life.gaiam.com/article/top-10-ways-reduce-your-risk-heart-disease

## References

* ↑ World Health Organization. Cardiovascular diseases (CVDs) [Internet]. 2013 [updated 2013 Mar; cited 2014 Sep 26]. Fact sheet no.:317. Available from: http://www.who.int/mediacentre/factsheets/fs317/en/
* ↑ World Health Organization. The top 10 causes of death [Internet]. 2011 [updated 2011 June; cited 2014 Sep 26]. Fact sheet no.:310. Available from: http://www.who.int/mediacentre/factsheets/fs310/en/
* ↑ Manchanda SC, Madan K. Yoga and meditation in cardiovascular disease. Clin Res Cardiol. 2014;103:675–680. doi:10.1007/s00392-014-0663-9
* ↑ Sengupta P. Health impacts of yoga and pranayama: a state-of-the-art review. Int J Prev Med [Internet]. 2012 [cited 2014 Sep 25];3(7):444-458. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415184/
* ↑ Manchanda SC, Madan K. Yoga and meditation in cardiovascular disease. Clin Res Cardiol. 2014;103:675–680. doi:10.1007/s00392-014-0663-9
* ↑ Manchanda SC, Madan K. Yoga and meditation in cardiovascular disease. Clin Res Cardiol. 2014;103:675–680. doi:10.1007/s00392-014-0663-9
* ↑ Innes KE, Bourguignon C, Taylor AG. Risk indices associated with the insulin resistance syndrome, cardiovascular disease, and possible protection with yoga: a systematic review. J Am Board Fam Pract. 2005;18(6):491-519
* ↑ Jayasinghe SR. Yoga in cardiac health (a review). Eur J Cardiovasc Prev Rehabil. 2004;11(5):369-375
* ↑ Yang K. A review of yoga programs for four leading risk factors of chronic diseases. Evid Based Complement. 2007;4(4):487-491
* ↑ Mahajan AS, Reddy KS, Sachdeva U. Lipid profiles of coronary risk subjects following yogic lifestyle intervention. Indian Heart J. 1999;51:37–40
* ↑ Aivazyan TA, Zaitsev VP, Salenko BB, Yurenev AP, Patrusheva IF. Efficacy of relaxation techniques in hypertensive patients. Health Psychol. 1988;(7 Suppl):193–200
* ↑ Andrews G, Macmahon SW, Austin A, Byrne DG. Hypertension: comparison of drug and non-drug treatments. BMJ [Internet]. 1982 [cited 2014 Sep 25];284:15231526. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1498486/pdf/bmjcred00607-0023.pdf
* ↑ Cohen DL, Bloedon LT, Rothman RL, Farrar JT, Galantino ML, Volger S, Mayor C, Szapary PO, Townsend RR. Iyengar yoga versus enhanced usual care on blood pressure in patients with stage I hypertension: a randomized controlled trial. Evid Based Complement Alternat Med. 2011. doi:10.1093/ecam/nep130
* ↑ Dhameja K, Singh S, Mustafa MD, Singh KP, Banerjee BD, Agarwal M, Ahmed RS. Therapeutic effect of yoga in patients with hypertension with reference to GST gene polymorphism. J Altern Complement Med. 2012;18:1-7. doi:10.1089/acm.2011.0961
* ↑ Deepa T, Sethu G, Thirrunavukkarasu N. Effect of yoga and meditation on mild to moderate essential hypertensives. J Clinical Diagn Res. 2012;6: 21-26
* ↑ Frumkin K, Nathan RJ, Prout MF, Cohen MC. Nonpharmacologic control of essential hypertension in man: a critical review of the experimental literature. Psychosom Med. 1978;40:294–320
* ↑ Krishna BH, Pal P, Pal GK, Balachander J, Jayasettiaseelon E, Sreekanth Y, Sridhar MG, Gaur GS. Effect of yoga therapy on heart rate, blood pressure and cardiac autonomic function in heart failure. J Clin Diagn Res. 2014;8(1):12-16. doi:10.7860/JCDR/2014/7844.3983
* ↑ Madanmohan, Udupa K, Bhavanani AB, Shatapathy CC, Sahai A. Modulation of cardiovascular response to exercise by yoga training. Indian J Physiol Pharmacol. 2004;48:461–5
* ↑ McCaffrey R, Ruknui P, Hatthakit U, Kasetsomboon P. The effects of yoga on hypertensive persons in Thailand. Holist Nurs Pract. 2005;19:173-180. doi:10.1097/00004650-200507000-00009
* ↑ Murugesan R, Govindarajulu N, Bera TK. Effect of selected yogic practices on the management of hypertension. Indian J Physiol Pharmacol. 2000;44(2): 207-210
* ↑ Saptharishi L, Soudarssanane M, Thiruselvakumar D, Navasakthi D, Mathanraj S, Karthigeyan M, Sahai A. Community-based randomized controlled trial of non-pharmacological interventions in prevention and control of hypertension among young adults. Indian J Community Med. 2009;34:329–34. doi: 10.4103/0970-0218.58393
* ↑ Schwickert M, Langhorst J, Paul A, Michalsen A, Dobos GJ. Stress management in the treatment of essential arterial hypertension. MMW Fortschr Med. 2006;148:40–2
* ↑ Subramanian H, Soudarssanane MB, Jayalakshmy R, Thiruselvakumar D, Navasakthi D, Sahai A, Saptharishi LG. Non-pharmacological interventions in hypertension: a community-based cross-over randomized controlled trial. Indian J Community Med. 2011;36(3):191-196. doi:10.4103/0970-0218.86519
* ↑ Singh S, Malhotra V, Singh KP, Madhu SV, Tandon OP. Role of yoga in modifying certain cardiovascular functions in type 2 diabetic patients. J Assoc Physicians India. 2004;52:203–6
* ↑ Mahajan AS, Reddy KS, Sachdeva U. Lipid profiles of coronary risk subjects following yogic lifestyle intervention. Indian Heart J. 1999;51:37–40
* ↑ Krishna BH, Pal P, Pal GK, Balachander J, Jayasettiaseelon E, Sreekanth Y, Sridhar MG, Gaur GS. Effect of yoga therapy on heart rate, blood pressure and cardiac autonomic function in heart failure. J Clin Diagn Res. 2014;8(1):12-16. doi:10.7860/JCDR/2014/7844.3983
* ↑ Manchanda SC, Narang R, Reddy KS, Sachdeva U, Prabhakaran D, Dharmanand S. Rajani M, Bijlani R. Retardation of coronary atherosclerosis with yoga lifestyle intervention. J Assoc Physicians India. 2000;48:687–94
* ↑ Aivazyan TA, Zaitsev VP, Salenko BB, Yurenev AP, Patrusheva IF. Efficacy of relaxation techniques in hypertensive patients. Health Psychol. 1988;(7 Suppl):193–200
* ↑ Wang J, Xiong X, Liu W. Yoga for essential hypertension: a systematic review. PLoS ONE. 2013;8(10):e76357. doi:10.1371/journal.pone. 0076357