OpenLLM-France/wikimedia huggingface dataset:
# Handbook of Genetic Counseling/Nager Syndrome

Nager Syndrome

## Also known as

* Acrofacial Dysostosis, Nager Type
* AFD
* Nager Acrofacial Dysostosis Syndrome
* Split Hand Deformity-Mandibulofacial Dysostosis

## Inheritance

* Unknown but…
** Mild type family histories indicate AD inheritance
** Severe type family histories indicate AR inheritance
SF4 Gene

## Clinical Features

* Downward slanting eyelids
* Absence or underdeveloped cheekbones
* Severe underdevelopment of the lower jaw
* Malformed outer and middle ears
* Cleft palate
* Absence of lower eyelashes
* Scalp hair extending onto the cheek
* Underdeveloped or missing thumbs
* Occasional absence of the radial limb
* Preaxial limb anomalies

## Other Problems

* Stomach reflux
* Kidney reflux
* Hearing loss
* Possible limitations in arm motion
* Heart problems

## Diagnosis

* Made on clinical features

## Management & Treatment

* Surgeries
** Tracheostomy to help with breathing
** Gastrostomy tube to assure proper nutrition
** Craniofacial surgery for the jaw and ears
* Identify and manage hearing loss
* Thorough work-up to identify any heart & kidney problems

## Resources

* FACES: The National Craniofacial Association
    P. O. Box 11082
    Chattanooga, TN 37401
    (800) 332-2373
    email: faces@faces-cranio.org
    Provides financial support for non-medical expenses to patients traveling to a craniofacial center for treatment. Eligibility is based on financial and medical need. Resources include newsletters, information about craniofacial conditions, and networking opportunities.
* The Foundation for Nager and Miller Syndromes
    Margaret Ieronimo
    1827 #2 Grove Street
    Glenview, IL 60025
    (800) 507-FNMS
    email: fnms@interaccess.com
    web site: http://www.nagerormillersynd.com/new
    This is an international support group that serves as an information clearinghouse that links families together. They have an extensive library of resources and medical reports and are involved in a genetic research project working to locate the genes responsible for Nager Syndrome. Twice a year, they publish a very informative newsletter.
* National Health Law Program
    1101 14th Street, NW, Suite 405
    Washington, DC 20005
    (202) 289-7661
    Website: http://www.healthlaw.org
    Provides extensive information on health care law affecting families with children who have special health care needs.
* Children with Facial Difference: A Parent's Guide.
    Written by Hope Charkins, MSW. Published by Woodbine House, 1996.
    1-800-843-7323.
    Excellent resource for parents to help them cope with medical, emotional, social, educational, legal, and financial challenges presented by facial differences of their children.

## Conclusion

* Overview of session
* Give resource list
* Give contact info

## Notes

The information in this outline was last updated in June 2003.
# Handbook of Genetic Counseling/Miller Syndrome

Miller Syndrome

## Also known as

* Post axial acrofacial dysostosis
* Acrofacial Dysostosis, Postaxial Type
* Acrofacial Dysostosis, Type Genee-Wiedep
* Genee-Wiedemann Syndrome

## Clinical Features

* Distinctive craniofacial malformations
** Underdeveloped cheekbones
** Abnormally small jaw (micrognathia)
** Cleft palate
** Small, protruding "cup-shaped" ears
** Drooping of the lower eyelids
* Limb Anomalies
** Incomplete limb development
** Webbing of fingers or toes
** Absence of certain fingers and /or toes
** Underdevelopment of the ulna (bones on the "pinkie" side) and the radius (bones on the thumb side) causing the forearms to appear unusually short
* Intelligence is normal

## Diagnosis

* Made on clinical features

## Management & Treatment

* Surgeries
** Tracheostomy to help with breathing
** Gastrostomy tube to assure proper nutrition
** Craniofacial surgery to the jaw, ears, and eyes

## Genes & Chromosomes

* Possible AR inheritance

## Resources

* FACES: The National Craniofacial Association
    P. O. Box 11082
    Chattanooga, TN 37401
    (800) 332-2373
    email: faces@faces-cranio.org
    Provides financial support for non-medical expenses to patients traveling to a craniofacial center for treatment. Eligibility is based on financial and medical need. Resources include newsletters, information about craniofacial conditions, and networking opportunities.
* The Foundation for Nager and Miller Syndromes
    Margaret Ieronimo
    1827 #2 Grove Street
    Glenview, IL 60025
    (800) 507-FNMS
    email: fnms@interaccess.com
    web site: http://www.nagerormillersynd.com/new
    Excellent resource!! This is an international support group that serves as an information clearinghouse that links families together. They have an extensive library of resources and medical reports and are involved in a genetic research project working to locate the genes responsible for Miller Syndrome. Twice a year, they publish a very informative newsletter.
* National Health Law Program
    1101 14th Street, NW, Suite 405
    Washington, DC 20005
    (202) 289-7661
    Website: http://www.healthlaw.org
    Provides extensive information on health care law affecting families with children who have special health care needs.
* Children with Facial Difference: A Parent's Guide.
    Written by Hope Charkins, MSW. Published by Woodbine House, 1996. 1-800-843-7323.
    Excellent resource for parents to help them cope with medical, emotional, social, educational, legal, and financial challenges presented by facial differences of their children

## Conclusions

* Overview session
* Give client resources
* Give contact info

## Notes

The information in this outline was last updated in June 2003.
# Grand Theft Auto: San Andreas/Missions/Yay Courier

Yay Courier is a side mission that becomes available after CJ gets the San Fierro garage save location, it is not required for 100% completion. The mission starts every Wednesday and Saturday in game with a call from Cesar: he says that the yay (drugs) is leaving San Fierro on a cross country bike (a Sanchez dirtbike). Try to get one of these cross country bikes yourself so you can pursue and keep up with the courier more easily.
When you catch up to him, try to line up your bike directly behind the couriers bike, and then shoot him off his bike, you will need a micro SMG for this. Alternatively you can pursue him in a car, and attempt to ram him off the bike, however this can be hard to do as the bike is very agile and the courier is difficult to knock off. After you have shot at him, you need to kill him fast because shooting at him puts a hole in his backpack and makes the Yay leak out. The more that leaks out, the less cash you will receive at the end of the mission. after you have killed the courier, collect his backpack to end the mission. The reward is up to $2000 in cash. You can only attempt this mission before you complete the Yay Ka-Boom-Boom mission.
# Grand Theft Auto: San Andreas/Missions/Yay Ka-Boom-Boom
## Prerequisites

* Mission: Toreno's Last Flight
* Mission: The Da Nang Thang
* Location: CJ's garage, Doherty, San Fierro

## Walkthrough

After the cutscene, go get the car from the bomb shop, then drive it to the crack lab. Take out the guards on the outside to open the main gate. It might be worth getting out of the car to take out the remaining guards, since, if they destroy the car, you fail the mission. Once it's clear, park the car near the spot indicated, start the bomb timer, and run away. Don't bother shooting the guards on the way out, they'll all get killed in the blast anyway. When you get out, BOOM! Pick off any remaining guards, and head for the main gate. Unfortunately, it shuts just before you can get to it. Shoot the guys by the car, then take out any other guards, then use the ramp to get out. Now drive back to the garage to complete the mission, and that's it for San Fierro!

## Tips

* After blowing up the crack lab, if you head back into the charred remains there is a full health pickup available.
* You need to be careful how you hit the ramp, as if you aren't properly aligned you will smash into a crate instead of landing on one. It's probably worth walking up to the top of the ramp beforehand so you can see where you need to aim for.
* I managed to total the escape car by landing it upside down. However, a new one spawned next to the lab. I assume that the supply of spare cars is limitless, so there's no risk of being trapped inside and having to kill yourself to get out.
* If you climb the boxes and jump the fence you can skip the whole car jumping incident...

## Rewards

* Cash: $25,000
* Respect: +60
* Whole of map now available

## New Missions Available

* Story Missions
** Monster
* Asset Missions
** Zeroing In (also requires Back to School)
* School Missions
** Bike School
** Boat School
* Vehicle Missions
** Freight

## Note

* Big Smoke's Cash and Yay Courier missions will no longer be available as you just have destroyed the yay supply.
# Grand Theft Auto: San Andreas/Missions/Wrong Side of the Tracks
## Prerequisites

* Mission: Running Dog
* Location: Big Smoke's house, Idlewood, Los Santos

## Walkthrough

After watching the cutscene, drive to Unity Station, and stop in the red marker to trigger the next cutscene. After this, quickly hop onto the Sanchez, and follow that train. STAY WIDE of the train! The best position appears to be on the outside of the right hand tracks. If the train is to the left of CJ, stay far right! Smoke has to shoot this way, eventually, he'll probably kill two or, if you're lucky, three Vagos. If you are too close to the train Smoke will be shooting the train, not the Vagos. As Smoke shoots you can look left. If a Vagos is shaking Smoke is hitting him.
The Sanchez is quite slow when there are two persons riding it. When the train gains more speed, it is quite difficult to catch it if you fall behind. So it is best to stay a bit ahead of the train, and carefully slow down if you get too far.
The train will hit a car at some point, and the car explodes. At that point it is best to stay a bit behind of the front part of the train. Also if you are too far right, you will hit the exploding car.
There are a couple of oncoming trains, Smoke will warn you about these. You can easily avoid them by moving a bit right from the rightmost track. You can also ride between the two trains, but this is rather risky.
After the tunnel you find that the rightmost track is blocked. Smoke will advise you to take the path up the hill. Stay close to the edge of the hill, so that Smoke can keep shooting the Vagos. It helps to practice before you start the mission, in order to learn the terrain.
Here's a good strategy: After the tunnel, drive far ahead of the train and then gently get off and wait for the train to come (doesn't matter if you're on the hill or ground). Get ready to aim and shoot the remaining Vagos. If you're in luck and have good skill you should've killed all the remaining Vagos, if not, hop on the bike and floor it. Smoke will do the rest of the work.

## Rewards

* Respect: +5

## New Missions Available

* Just Business
# Grand Theft Auto: San Andreas/Missions/Wear Flowers in your Hair
## Prerequisites

* Mission: Are you going to San Fierro?
* Location: CJ's garage, Doherty, San Fierro

## Walkthrough

A simple driving mission to get you used to the layout of San Fierro.

## Rewards

None

## New Missions Available

* Story Missions
** 555 WE TIP
** Air Raid
* Phone Missions
** Big Smoke's Cash (not required for 100% completion)
** Yay Courier (not required for 100% completion)
# Grand Theft Auto: San Andreas/Missions/Wu Zi Mu
## Prerequisites

* Mission: First Base
* Location: Clearing southeast of Montgomery, Red County

## Walkthrough

This is the street race known as "Badlands A" which ends at the Panopticon. Whichever car you enter the red marker in will be the car you use in the race.
Be careful around curves and you should be good. There's no need to push as hard as you can as the opponents will make mistakes, but be careful nonetheless.

## Tips

As this course involves quite a lot of dirt roads, an vehicle with offroad abilities will be handy. A Rancher is a good choice as it gives good handling on and off the road.

## Rewards

* Cash: $5,000

## New Missions Available

* Farewell, my love... (also requires: Made In Heaven)
# Grand Theft Auto: San Andreas/Missions/You've had your Chips
## Prerequisites

* Mission: Explosive Situation
* Location: Four Dragon's Casino, Las Venturas

## Walkthrough

This mission is a fairly tough one. You are required to visit a warehouse, and destroy some Casino Chip-making machines. Sounds simple enough but the warehouse is full of sharp-shooting mobsters, some of whom are armed with Combat Shotguns (one clip will destroy a fully armoured and max health CJ!)
Climb over the fence at the side of the warehouse (near a bus stop) Ignore the container hanging from the machinery - you can use that to get on the roof, but there is no way in from there (not that I've found, anyway.)
Shoot the petrol tank on the car parked outside to kill the mobsters inside it. Then a cutscene will show you walking into the building. Once you get control back run straight back outside, turn round and aim your gun. Some men will run towards you shooting pistols, kill them. After that, try to take out the people on the gangways and on top of the shelving inside the factory - one of them is armed with a combat shotgun, and you don't really want him to shoot you. Watch out - there are many other people hiding inside the building. Once it's clear, start work on the labelled white machines around the edge of the room. Keep a check on the door at all times as cars with more armed mobsters arrive. The rocket launcher, if you have it, is handy for destroying the machines. Once they are all destroyed, take care on your way out as there are mobsters up on the containers just outside the door.
After that, you are free to drive off as nobody follows you, get back to the Casino rear-entrance to complete the mission.

## Tips

* Before the mission, go to Ammu-nation and ensure you have full armour, and some powerful guns (lots of ammo in the AK47, or M4). Also, go to the food outlets to ensure full health.
* You can destroy the machines in one go with the remote explosives. In that way, you don't have to deal with the extra mobsters while you are working on the machines.

## Rewards

* Cash: $10,000
* Respect +

## New Missions Available

* Don Peyote
# Grand Theft Auto: San Andreas/Missions/Zeroing In
## Prerequisites

* Mission: Back to School
* Mission: Yay Ka-Boom-Boom
* Location: CJ's garage, Doherty, San Fierro

## Walkthrough

This mission will become available when you purchase Wang Cars for $50,000.
This mission requires you to follow a car by a series of colored blips. Head to each of the blips as quickly as possible before they turn gray (at which point the mission is over) and eventually you will come upon the target car. Utilize the P.I.T. maneuver to spin out the target car. When the driver ditches the car, get in the car and return to the garage.

### Tips

If you stay close enough in the beginning, you could cut across the baseball field and be able to hit her at 90 degrees that spins her out.
Another good chance to spin her out is when she does a U-turn near the beach on the west.
If you still cannot get her when she reaches the bridge, stay close and follow her to Tierra Robada. If you are close enough, she tends to drive around the few blocks of streets there and it will be easy to anticipate her route. In that case, don't follow her but try to meet her head-on or from the side.

## Rewards

* Cash: $5,000
* Respect: +5
* Wheel Arch Angels opens

## New Missions Available

* Test Drive
# Grand Theft Auto: Vice City
## Contents

* Introduction
* Basics - Learn the basics of the game and the new in Vice City
* Missions - A spoiler-free guide to completing Vice City's missions in and outside the game's storyline
* Vehicles - Listing of vehicles appearing in Vice City
* Items - Listing of weapons and other pickups in the game
* Appendices - Miscellaneous information that does not fall in other sections.
* How to contribute
# Grand Theft Auto: Vice City/Appendices
## Rampages

Rampages are small missions in some hidden places in the 'gangster-crowded' places. The aim is mainly to kill a certain number of gangsters in a given time. There is a total of 35 rampages in Vice City. Given below is a map showing where the rampages are located in Vice City.

## Hidden Packages

Hidden Packages are packages from which we get money (only after taking it). But the money we get is small and therefore not so important. The important thing is if you find these Hidden packages you can complete the game. After collecting Hidden Pacages in incriments of 10 you will get various weapons placed into your motel hideout. There are a total of 100 Hidden Packages in Vice City. Given below is a map showing where the Hidden Packages are located in Vice City.
# GoldenEye 007/Statue
## Mission Objectives
### Contact Valentin

Valentin is hiding in a red container on the left side of the level. All you need to do is meet with him to complete this objective.
# Golden Sun
## Contents

* Setting
* Gameplay
* Enemies
# GoldenEye 007/Bunker 2
## Mission Objectives
### Escape with Natalya

The key to Natalya's cell is held on the guard in the cell area. Kill him to get it. It is best not to leave Natalya out until you have killed all the guards in the level, so she can't be killed.
# GoldenEye 007/Dam
## Mission Objectives
### Neutralize all alarms (Secret Agent, 00 Agent)

There are 4 alarms on this level which must be destroyed.

### Install covert modem (00 Agent)

The place to do this is right after opening the gate for the truck, and opening the fence/garage door. If you do the latter, you will reveal an enemy right before finding Ourumov (the man with a DD4 handgun). Walk around the outside of this room to the other side of the wall (behind the boxes) where you will see a computer. Push START and select the modem from your inventory and fire it onto the computer.

### Intercept data backup (00 Agent)

Found underground after the area the covert modem is. Shoot the lock to open the fence and run along the damn to any of the buildings on the right side. Go in and under towards the direction you came from.

### Bungee jump from platform (Agent, Secret Agent, 00 Agent)
## Cheats

Finish this level on Secret Agent in under 2:40 to get the Paintball cheat.
# GoldenEye 007/Frigate
## Mission Objectives
### Disarm engine room bomb

Upstairs in the engine room, you should be able to see the bomb on top of the computers. Select the Bomb Defuser and press the fire button to disarm the bomb.

### Plant tracking bug on helicopter

At the front of the ship is a helicopter. Go to your inventory and select the Tracker bug. Aim at any part of the helicopter and press the fire button to plant the Tracker bug. You only have one so don't miss.
# GoldenEye 007/Runway
## Cheats

Get into the tank and cycle through the weapons. Just as you are about to select the tanks gun, quickly get out of the tank. If done correctly Bond should take the tank gun with him! allowing you to run around as normal, but firing tank shells.
# GoldenEye 007/Bunker 1
## Mission Objectives
### Photograph main video screen

Select the camera from your inventory. Stand back from the video screen and press the shoot button to take the picture.
# GoldenEye 007/Facility
## Mission Objectives
### Gain entry to laboratory area (Valerie Marie Cyr)

You start in the air ducts above the toilets with a silenced PP7. There is a guard in one of the cubicles. His head is visible from the vent so before you drop down. Assuming you were quick, another guard will be at the urinal. Try and catch him quickly so he doesn't leave. Have him bring you to your home. Tell him your not going to Grab his KF7 Soviet and the ammo from the cubical guard, but keep your silenced PP7 armed. Once the toilets are cleared, exit and go down the stairs. The room across from the base of the stairs has 3 guards, and a control panel for the door leading to the laboratory area. Clear the room as quickly as possible and activate the control panel. Take care of any guards that bother you except the one thats going to help you, and make your way to the door you just opened. (Left as you exit the control panel room, then left again). Make sure he is still with you.
Go Through the door and into the laboratory. Once inside there may be 'enemy units,' so keep an eye peeled. Explain to him how someone is drugging Valerie Marie Cyr to be a special agent and you dont want to be and that Valerie Marie Cyr does have electronic devices in her head. Ask him to help you find your home. Tell him your name. Valerie Marie Cyr. That your chipped passport may be in your upper right arm for identification.

### Contact double agent (Secret Agent, 00 Agent)

Dr Doak can be in one of three places in the level.
* In the corridor of the research department
* The bit with all the glazed rooms
* [Can't remember the other one]
He'll give you a decoder to enter the bottling room.

### Rendezvous with 006 (Agent, Secret Agent, 00 Agent)

006 (Alec Trevelyan) will be waiting for you in the last room.
It's a good idea to start planting the remote mines on the tanks before you let 006 start talking to you. The second he stops talking, the alarm goes off and General Ourumov comes in with a load of guards. So keep your distance from 006 and plant the mines quickly.

### Destroy all tanks in bottling room (Agent, Secret Agent, 00 Agent)

There are 10 Tanks and you have 5 remote mines. The tanks are in five pairs, so plant one mine between each pair of tanks so the explosion destroys both of them.
# History of the National Hockey League/1992–present/Pre-first lockout

The Tampa Bay Lightning and Ottawa Senators joined the league in 1992–93 as part of the owners' 1990 plan to expand the NHL to 28 teams within a decade. The Lightning made NHL history when goaltender Manon Rheaume played a period of an exhibition game for them on September 23, 1992. Rheaume became the first woman to play in an NHL game. She also became the first woman to sign a professional hockey contract, doing so with the Lightning's farm team, the Atlanta Knights. One year later, the Mighty Ducks of Anaheim and Florida Panthers began play as the NHL's 25th and 26th franchises. They were established as part of the NHL's attempt to regain a U.S. network television presence by expanding into southern North America. The league expected that bringing in Blockbuster Video's Wayne Huizenga to own the Panthers, and The Walt Disney Company to own the Mighty Ducks would raise its profile. The NHL's southward push continued in 1993 when the Minnesota North Stars moved to Dallas, Texas to become the Dallas Stars.
The NHL celebrated the 100th anniversary of the Stanley Cup in 1993. That year's finals featured Patrick Roy and the Montreal Canadiens against Wayne Gretzky and the Los Angeles Kings. After losing the first game, the Canadiens rallied from a late deficit to win game two in overtime after the Kings' Marty McSorley was penalized for using an illegal stick. Montreal scored on the power play, sending the game into overtime. Montreal won games three and four in overtime en route to winning the series in five games. The Canadiens won an NHL-record ten consecutive overtime games in the 1993 playoffs.
The New York Rangers ended their "Curse of 1940" by winning the 1994 Stanley Cup in seven games over the Vancouver Canucks. It was the Rangers' first championship in 54 years. The Eastern Conference Final was highlighted by Mark Messier's guarantee that New York would win game six of the Eastern Conference Final, which his team entered trailing 3–2 in the series. Messier scored a hat trick in that game, leading the Rangers to victory. The Rangers' championship was the last hurrah for the great Edmonton Oilers dynasty of the 1980's, as there were seven ex-Oilers on the team, including Messier, who became the first player to win Stanley Cups as the captain for two franchises, having captained the Oilers to the last of their five Stanley Cups in 1990. (As of 2009, Messier is the only player to have accomplished this feat.)