# Radiation Oncology/CNS

* Front Page: Radiation Oncology | RTOG Trials | Randomized Trials

## Clinical Sections

Introduction
Adult:
* Glioma
* Meningioma
* Primary CNS Lymphoma
* Pineal Gland Tumors
* Metastatic to brain
* CSF involvement
* Spine
* Cerebral cavernous malformation
* Miscellaneous CNS Tumors
Pediatric:
* Craniopharyngioma
* Glioma:
** Optic Pathway Glioma
** Brainstem Glioma
** Pilocytic Astrocytoma
* Germinoma
* Ependymoma
* Choroid Plexus Tumor
* Medulloblastoma
* CNS PNET
* Pineal Gland tumors
* Atypical Teratoid Rhabdoid Tumor (AT/RT)
* Retinoblastoma
Benign:
* Acoustic Neuroma (Vestibular Schwannoma)
* Pituitary Adenoma
* Trigeminal Neuralgia
* Sphenopalatine Neuralgia
* Chronic Cluster Headaches
* Arteriovenous Malformation (AVM)
* Cavernous Malformation
* Hypothalamic Hamartoma
* Glomus Jugulare (Paraganglioma)
* Epilepsy
* Cancer pain
See also:
* Hemangiopericytoma
Proton therapy
CNS Toxicity:
* Brain toxicity
* Brainstem toxicity
RTOG Brain Trials

## 2007 WHO Classification

Neuroepithelial Tumors
* Astrocytic Tumors
** Pilocytic astrocytoma 9421/1
*** Pilomyxoid astrocytoma 9425/3
** Subependymal giant cell astrocytoma 9384/1
** Pleomorphic xanthoastrocytoma 9424/3
** Diffuse astrocytoma 9400/3
*** Fibrillary astrocytoma 9420/3
*** Protoplasmic astrocytoma 9410/3
*** Gemistocytic astrocytoma 9411/3
** Anaplastic astrocytoma 9401/3
** Glioblastoma 9440/3
*** Giant cell glioblastoma 9441/3
*** Gliosarcoma 9442/3
** Gliomatosis cerebri 9381/3
* Oligodendroglial tumours
** Oligodendroglioma 9450/3
** Anaplastic oligodendroglioma 9451/3
* Oligoastrocytic tumours
** Oligoastrocytoma 9382/3
** Anaplastic oligoastrocytoma 9382/3
* Ependymal tumours
** Subependymoma (WHO Grade 1) 9383/1
** Myxopapillary ependymoma (WHO Grade 1) 9394/1
** Ependymoma (WHO Grade 2) 9391/3
*** Cellular 9391/3
*** Papillary 9393/3
*** Clear cell 9391/3
*** Tanycytic 9391/3
** Anaplastic ependymoma (WHO Grade 3) 9392/3
* Choroid plexus tumours
** Choroid plexus papilloma 9390/0
** Atypical choroid plexus papilloma 9390/1*
** Choroid plexus carcinoma 9390/3
* Other neuroepithelial tumours
** Astroblastoma 9430/3
** Chordoid glioma of the third ventricle 9444/1
** Angiocentric glioma 9431/1*
* Neuronal and mixed neuronal-glial tumours
** Dysplastic gangliocytoma of cerebellum (Lhermitte-Duclos) 9493/0
** Desmoplastic infantile astrocytoma/ganglioglioma 9412/1
** Dysembryoplastic neuroepithelial tumour 9413/0
** Gangliocytoma 9492/0
** Ganglioglioma 9505/1
** Anaplastic ganglioglioma 9505/3
** Papillary glioneuronal tumor 9509/1*
** Rosette-forming glioneuronal tumour of the fourth ventricle 9509/1*
** Central neurocytoma 9506/1
** Extraventricular neurocytoma 9506/1*
** Cerebellar liponeurocytoma 9506/1*
** Paraganglioma of the filum terminale 8680/1
Tumours of the pineal region
** Pineocytoma 9361/1
** Pineal parenchymal tumour of intermediate differentiation 9362/3
** Pineoblastoma 9362/3
** Papillary tumour of the pineal region 9395/3*
Embryonal tumours
* Medulloblastoma 9470/3
** Desmoplastic/nodular medulloblastoma 9471/3
** Medulloblastoma with extensive nodularity 9471/3*
** Anaplastic medulloblastoma 9474/3*
** Large cell medulloblastoma 9474/3
* CNS primitive neuroectodermal tumours (PNETs)
** CNS PNET, NOS 9473/3
** CNS neuroblastoma 9500/3
** CNS ganglioneuroblastoma 9490/3
** Medulloepithelioma 9501/3
** Ependymoblastoma 9392/3
* Atypical teratoid / rhabdoid tumour 9508/3
Tumors of the Cranial and Paraspinal Nerves
* Schwannoma (Neurilemoma, neurinoma) 9560/0
** Cellular 9560/0
** Plexiform 9560/0
** Melanotic 9560/0
* Neurofibroma 9540/0
** Plexiform 9550/0
* Perineurioma 9571/0
** Intraneural perineurioma 9571/0
** Soft tissue perineurioma 9571/0
* Malignant peripheral nerve sheath tumour (MPNST) 9540/3
** Epithelioid 9540/3
** MPNST with divergent mesenchymal and / or epithelial differentiation 9540/3
** Melanotic 9540/3
Tumors of the Meninges
* Tumours of meningothelial cells
** Meningioma 9530/0
* Mesenchymal tumours
** Lipoma 8850/0
** Angiolipoma 8861/0
** Hibernoma 8880/0
** Liposarcoma (intracranial) 8850/3
** Solitary fibrous tumour 8815/0
** Fibrosarcoma 8810/3
** Malignant fibrous histiocytoma 8830/3
** Leiomyoma 8890/0
** Leiomyosarcoma 8890/3
** Rhabdomyoma 8900/0
** Rhabdomyosarcoma 8900/3
** Chondroma 9220/0
** Chondrosarcoma 9220/3
** Osteoma 9180/0
** Osteosarcoma 9180/3
** Osteochondroma 9210/0
** Haemangioma 9120/0
** Epithelioid haemangioendothelioma 9133/1
** Haemangiopericytoma 9150/1
** Angiosarcoma 9120/3
** Kaposi sarcoma 9140/3
* Primary melanocytic lesions
** Diffuse melanocytosis 8728/0
** Melanocytoma 8728/1
** Malignant melanoma 8720/3
** Meningeal melanomatosis 8728/3
* Other neoplasms related to the meninges
** Haemangioblastoma 9161/1
Lymphomas and Hematopoietic Neoplasms
* Malignant lymphomas 9590/3
* Plasmacytoma 9731/3
* Granulocytic sarcoma 9930/3
Germ Cell Tumors
* Germinoma 9064/3
* Embryonal carcinoma 9070/3
* Yolk sac tumour 9071/3
* Choriocarcinoma 9100/3
* Teratoma 9080/1
** Mature 9080/0
** Immature 9080/3
** Teratoma with malignant transformation 9084/3
* Mixed germ cell tumours 9085/3
Tumors of the Sellar Region
* Craniopharyngioma 9350/1
** Adamantinomatous 9351/1
** Papillary 9352/1
* Granular cell tumour 9582/0
* Pituicytoma 9432/1*
* Spindle cell oncocytoma of the adenohypophysis 8291/0*
Metastatic Tumors