# Radiation Oncology/TOC

* Front Page: Radiation Oncology | RTOG Trials | Randomized Trials
TABLE OF CONTENTS

## Preface

* Introduction
* Instructions for authors
* Author List
* Cancer epidemiology
* Cancer staging

## Treatment by Disease Site
### Central Nervous System Tumors

* Introduction
* Glioma
* Meningioma
* Primary CNS Lymphoma
* Pineal Gland Tumors
* Metastatic to brain
* CSF involvement
* Spine
* Miscellaneous CNS Tumors
Pediatric:
* Craniopharyngioma
* Germinoma
* Ependymoma
* Optic Pathway Glioma
* Brainstem Glioma
* Pilocytic Astrocytoma
* Medulloblastoma
* CNS PNET
* Pineal Gland tumors
* Atypical Teratoid Rhabdoid Tumor (AT/RT)
* Retinoblastoma
Benign:
* Acoustic Neuroma (Vestibular Schwannoma)
* Trigeminal neuralgia
* Sphenopalatine Neuralgia
* Chronic Cluster Headaches
* Arteriovenous Malformation (AVM)
* Cavernous Malformation
* Glomus Jugulare (Paraganglioma)
* Cancer pain

### Skull Base Tumors

* Chordoma
* Chondrosarcoma

### Head and Neck Tumors

* General Head and Neck
* Post-operative Head and Neck
* Oral cavity
* Pharynx:
** Nasopharynx
** Oropharynx
** Hypopharynx
* Larynx
* Sinonasal tumors:
** Nasal cavity
** Maxillary sinus
** Ethmoid sinuses
* Salivary glands
* Unknown primary
* Thyroid
* IMRT

### Eye and Orbit

* Choroidal metastasis
* Ocular melanoma
* Graves' Ophthalmopathy
* Retinoblastoma

### Thoracic Tumors

* Lung Cancer
** NSCLC
** SCLC
* Carcinoid of the lung
* Mesothelioma
* Thymoma
* Superior Vena Cava Syndrome

### Gastrointestinal Tumors

* Esophagus
* Stomach
* Gastrointestinal stromal tumors
* Pancreas
* Bile duct (Cholangiocarcinoma)
* Gall bladder
* Liver
* Small intestine
* Colon
* Rectum
* Anal canal

### Genitourinary Tumors

* Prostate
* Bladder
* Kidney
* Testis
* Penis
* Urethra
* Renal pelvis and ureter
Benign
* Peyronie's Disease

### Gynecologic Tumors

* Vulva
* Vagina
* Cervix
** Cervical brachytherapy
* Uterus
** Endometrial carcinoma
** Leiomyosarcoma
* Fallopian tube
* Ovary

### Breast Cancer

* Breast

### Hematologic Malignancies

* Hodgkin lymphoma
* Non-Hodgkin lymphoma
* Primary CNS lymphoma
* Leukemia
* Multiple myeloma and plasmacytoma
* Waldenstroms macroglobulinemia
* Mycosis fungoides
* Cutaneous B-cell lymphoma
* Spleen Irradiation
* Total Body Irradiation
* Miscellaneous

### Sarcoma

Soft tissue tumors:
* Soft tissue sarcomas
* Retroperitoneal sarcomas
* Dermatofibrosarcoma protuberans
* Synovial sarcoma
* Angiosarcoma
* Malignant Peripheral Nerve Sheath Tumor and Malignant Intracerebral Nerve Sheath Tumor
* Hemangiopericytoma
* EBV-associated Smooth Muscle Tumor (EBV-SMT)
Bone tumors:
* Osteosarcoma
* Chondrosarcoma
* Ewing's sarcoma
* Fibrosarcoma
* Chordoma
* Bone PNET
Benign:
* Angiomyxoma

### Skin

* Melanoma
* Non-melanoma skin cancer
* Merkel cell carcinoma
* Kaposi's sarcoma
* Eccrine Porocarcinoma
* Extramammary Paget's disease

### Neuroendocrine Tumors

* Medullary carcinoma of the thyroid
* Small cell lung cancer
* Large cell neuroendocrine carcinoma of the lung
* Paraganglioma
* Adrenocortical Carcinoma
* Merkel cell
* Neuroblastoma

### Germ cell tumors

* Testicular GCTs
* CNS GCTs

### Pediatric Tumors

* Brain Tumors
** Craniopharyngioma
** Germ cell tumors
** Ependymoma
** Medulloblastoma
** Optic Pathway Glioma
** Pilocytic Astrocytoma
** CNS PNET
** Atypical Teratoid Rhabdoid Tumor
* Nephroblastoma (Wilms')
* Neuroblastoma
* Rhabdomyosarcoma
* Retinoblastoma
* Ewing's sarcoma
* Bone PNET
* Pediatric Hodgkin's
* Burkitt's Lymphoma

### Miscellaneous Tumors

* Miscellaneous

### Benign Non-Neoplastic Diseases

* Trigeminal Neuralgia
* Sphenopalatine Neuralgia
* Chronic Cluster Headaches
* Acoustic neuroma (vestibular schwannoma)
* Graves' Disease
* Heterotopic ossification
* Ankylosing spondylitis
* Heel Spurs
* Keloid
* Angiomyxoma
* Peyronie's Disease
* Vascular Brachytherapy
* Arteriovenous malformation
* Cavernous malformation

### Palliation

* Overview of palliation
* Superior vena cava syndrome
* Spinal cord compression
* Bone mets
* Brain mets
* NSCLC palliation
* Pelvic palliation

## Treatment toxicity

* Grading of toxicity
* NTCP (Normal tissue complication probability)
* Normal tissue tolerance (Emami estimates)
* Brain
* Vision
* Head & Neck
* Heart
* Lung
* Esophagus
* Small bowel
* Genitourinary
* Bone marrow
* Second malignancies
* Skin

## Supportive Care

* Supportive care (general)
* Anemia
* Cachexia
* Dyspnea
* Fatigue
* Gastrointestinal symptoms
* Skin care
* Head and neck
* Hot flashes
* Neurologic symptoms
* Pain
* Thromboembolism

## Radiation Techniques

* External Beam
** Cranial stereotactic radiosurgery (SRS)
** Stereotactic body radiation therapy (SBRT)
** Whole brain RT (WBRT)
** Cranio-Spinal Irradiation (CSI)
** Total Body Irradiation (TBI)
** Total Scalp Irradiation (TSI)
** Intensity modulated radiation therapy (IMRT)
** Image-guided radiotherapy
** Adaptive radiotherapy
* Brachytherapy
* Intraoperative RT (IORT)
* Unsealed sources
* Particle Therapy
** Neutrons
** Protons
** Charged Particles
* Hyperthermia

## Treatment Planning

* Contraindications to radiotherapy
* Anatomy
* Bone marrow distribution
* Examples of treatment fields
* Tumor motion
* IMRT
* Devices used in simulation
* Treatment of patients with pacemakers

## Other Topics
### Radiobiology

* Classic radiobiology
* Effect of time to treatment and overall treatment time
* Cancer biology
* Antibodies
* Small molecules
* Radiation modulators
* Radiation Sensitizers
* Radiation Protectors
* List of Chromosomes and their related cancer genes
* Tumor markers

### Health Technology Assessment

* Radiation Oncology/Cost-Effectiveness
* Radiation Oncology/Protons/Economics

## Drugs

* Chemotherapy drugs
* Chemotherapy combinations
* Endocrine drugs
* Cytokines and immunomodulators
* Immunosuppresive drugs

## Appendices
### Clinical trials

* Recent Studies Posted
* Numeric list of RTOG trials
* Search the NCI website for protocols - gives publication info for completed trials
* Other cooperative groups:
** ACOSOG
** CALGB
** COG
** ECOG
** EORTC
** GOG
** NCI-Canada
** NSABP
** SIOP trials
* Lists of current protocols:
** GRCOP list of active protocols - lists Fast Facts for several national protocols
** CTSU - Cancer Trials Support Unit, part of the NCI.

### Cancer statistics

* 2007 Cancer Facts and Figures - from the American Cancer Society, good resource for number of cases/year
* List of most commons (e.g. What is the 3rd most common pediatric extracranial malignancy?)
* Worldwide cancer statistics
* USA cancer statistics
* Survival curve terminology definitions

### Other

* AJCC/TNM staging editions
* Historical documents about radiation
* Karnofsky performance status scale
* Online tools
* Education
* Corporate

## Supplementary Material

* ASTRO meeting webcasts - ASTRO Spring Refresher Course, etc.
* Other meeting presentations
* National Cancer Institute PDQ (Physician Data Query) - information about treatment, supportive care, clinical trials, etc. An invaluable resource.
* Oncolink - U.Pennsylvania, provides summaries of trials presented at scientific meetings including ASTRO, ASCO, and others. Very nice.