# 2022 Internazionali Femminili di Tennis Città di Caserta – Singles

Varvara Gracheva was the defending champion but chose not to participate.
Kristina Mladenovic won the title, defeating Camilla Rosatello in the final, 6–4, 4–6, 7–6$^{(7–3)}$.

## Seeds

* Clara Burel (first round)
* Kristina Mladenovic (champion)
* Elina Avanesyan (second round)
* Despina Papamichail (first round)
* Moyuka Uchijima (semifinals)
* Simona Waltert (first round)
* Federica Di Sarra (quarterfinals)
* Daniela Vismane (quarterfinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| WC | Nuria Brancaccio | 4 | 1 | | | | | |
| | Camilla Rosatello | 6 | 6 | | | | | |
| | Camilla Rosatello | 6 | 6 | | Camilla Rosatello | 4 | 6 | 6$^3$ |
| | | | | 2 | Kristina Mladenovic | 6 | 4 | 7$^7$ |
| 5 | Moyuka Uchijima | 3 | 3 | 2 | Kristina Mladenovic | 6 | 4 | 7$^7$ |
| 2 | Kristina Mladenovic | 6 | 6 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | C Burel | 5 | 6 | 4 | | | | | | | | | | | | | |
| | K Gerlach | 7 | 2 | 6 | | K Gerlach | 7 | 0 | 4 | | | | | | | | |
| WC | N Brancaccio | 4 | 6 | 6 | WC | N Brancaccio | 5 | 6 | 6 | | | | | | | | |
| | M Bondarenko | 6 | 0 | 1 | | | | | | WC | N Brancaccio | 7$^7$ | 6 | | | | |
| | M Di Giuseppe | 2 | 6 | 6 | | | | | | 7 | F Di Sarra | 6$^1$ | 2 | | | | |
| WC | M Delai | 6 | 2 | 2 | | M Di Giuseppe | 6$^5$ | 1 | | | | | | | | | |
| Q | O Gavrilă | 1 | 5 | | 7 | F Di Sarra | 7$^7$ | 6 | | | | | | | | | |
| 7 | F Di Sarra | 6 | 7 | | | | | | | | | | | WC | N Brancaccio | 4 | 1 |
| 4 | D Papamichail | 6 | 6$^4$ | 6$^5$ | | | | | | | | | | | C Rosatello | 6 | 6 |
| | C Ferrando | 1 | 7$^7$ | 7$^7$ | | C Ferrando | 5 | 2 | | | | | | | | | |
| | P Marčinko | 5 | 6 | 6$^2$ | | C Rosatello | 7 | 6 | | | | | | | | | |
| | C Rosatello | 7 | 2 | 7$^7$ | | | | | | | C Rosatello | 6 | 6 | | | | |
| | A Prisăcariu | 6 | 6 | | | | | | | 8 | D Vismane | 3 | 1 | | | | |
| Q | E Malõgina | 3 | 4 | | | A Prisăcariu | 2 | 7$^7$ | 1 | | | | | | | | |
| WC | A Aragosa | 1 | 2 | | 8 | D Vismane | 6 | 6$^5$ | 6 | | | | | | | | |
| 8 | D Vismane | 6 | 6 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5 | M Uchijima | 6 | 6 | | | | | | | | | | | | | | |
| Q | A Raggi | 1 | 3 | | 5 | M Uchijima | 6 | 6 | | | | | | | | | |
| Q | F Bilardo | 2 | 3 | | Q | Z Kulambayeva | 4 | 3 | | | | | | | | | |
| Q | Z Kulambayeva | 6 | 6 | | | | | | | 5 | M Uchijima | 6 | 6 | | | | |
| | G Cé | 6 | 2 | 6$^6$ | | | | | | Q | D Cherubini | 3 | 1 | | | | |
| Q | D Cherubini | 4 | 6 | 7$^8$ | Q | D Cherubini | 6 | 7 | | | | | | | | | |
| Q | I Lavino | 2 | 3 | | 3 | E Avanesyan | 3 | 5 | | | | | | | | | |
| 3 | E Avanesyan | 6 | 6 | | | | | | | | | | | 5 | M Uchijima | 3 | 3 |
| 6 | S Waltert | 3 | 4 | | | | | | | | | | | 2 | K Mladenovic | 6 | 6 |
| WC | L Pigato | 6 | 6 | | WC | L Pigato | 5 | 6 | 6 | | | | | | | | |
| | B Turati | 3 | 3 | | | F Jorge | 7 | 2 | 3 | | | | | | | | |
| | F Jorge | 6 | 6 | | | | | | | WC | L Pigato | 2 | 5 | | | | |
| | M Helgø | 6 | 6 | | | | | | | 2 | K Mladenovic | 6 | 7 | | | | |
| Q | M Mutavdzic | 0 | 3 | | | M Helgø | 3 | 4 | | | | | | | | | |
| | C Dinu | 3 | 2 | | 2 | K Mladenovic | 6 | 6 | | | | | | | | | |
| 2 | K Mladenovic | 6 | 6 | | | | | | | | | | | | | | |