OpenLLM-France/wikimedia huggingface dataset:
# HLA-DR16

HLA-DR16(DR16) is a HLA-DR serotype that recognizes the DRB1*1601, *1602 and *1604 gene products. DR16 is found in the Mediterranean at modest frequencies. DR16 is part of the older HLA-DR2 serotype group which also contains the similar HLA-DR15 antigens.

## Alleles

DR16, DR2 and other serotype recognition of some DRB1*16 alleles :
| DRB1* | DR16 | DR2 | DR15 | Sample |
| allele | % | % | % | size (N) |
| 1601 | 41 | 29 | 19 | 703 |
| 1602 | 47 | 30 | 16 | 239 |
| 1604 | >50 | | | 1 |

## Disease associations

DR16 is associated with Chaga's cardiomyopathy, rheumatic heart disease, coronary artery ectasia, and chronic discoid lupus erythematosus.
DRB1*1601 is associated with tuberculosis risk
DRB1*1602: Juvenile rheumatoid arthritis, rheumatic heart disease, Takayasu arteritis Archived 2007-08-07 at the Wayback Machine, systemic sclerosis (SSc) & anti-DNA topoisomerase I (anti-topo I) antibody, melioidosis (Burkholderia pseudomallei infection)

### Extended linkage

DRB1*1601:DQA1*0102:DQB1*0502 haplotype is associated with tubeculousis risk
** *1602:DQA1*0102:DQB1*0502 haplotype: graves disease, cervical cancer (human papilloma virus infection), scleroderma
** *1602:DQA1*05:DQB1*0301 haplotype: rheumatic heart disease, systemic sclerosis

## Genetic Linkage

HLA-DR16 is genetically linked to HLA-DR51 and HLA-DQ5 serotypes.
# HLA-DR4

HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of moderate frequency alleles spread over large regions of the world.

## Serology

DR4 serological recognition of the gene products of some DRB1*04 alleles :
| DRB1* | DR4 | Sample |
| allele | % | size (N) |
| 04:01 | 98 | 5118 |
| 04:02 | 92 | 1029 |
| 04:03 | 92 | 748 |
| 04:04 | 89 | 2164 |
| 04:05 | 91 | 505 |
| 04:06 | 89 | 83 |
| 04:07 | 86 | 846 |
| 04:08 | 86 | 258 |
| 04:09 | 95 | 13 |
| 04:10 | 84 | 29 |
| 04:11 | 93 | 76 |
| 04:12 | >50 | 1 |
| 04:13 | >30 | 3 |
The serological identification of DR4 is good. The serology of DRB1*04:17 to *04:60 is unknown.

## Disease associations
### By serotype

DR4 is associated with extraarticular rheumatoid arthritis, hydralazine-induced female systemic lupus erythematosus, pemphigoid gestationis, pemphigus foliaceus, obstructive hypertrophic cardiomyopathy, IgA nephropathy, 'shared syndrome'-systemic sclerosis/rheumatoid arthritis and polymyalgia rheumatica.

### By allele

DRB1*04 is associated with increased risk for alopecia areata.
DRB1*04:01 is associated with multiple sclerosis, rheumatoid arthritis, type 1 diabetes, lyme disease induced arthritis. HLA-DRB1*04:01 gene variant is found three times more often in asymptomatic carriers of SARS-CoV-2 than in patients with symptoms of COVID-19. It is known that the prevalence of the HLA-DRB1*04:01 variant directly correlates with the latitude and longitude of the population. This variant of the gene is more common in northern and western Europe, which means that people of European descent are more likely to be asymptomatic carriers that can transmit the disease to more susceptible populations.
DRB1*04:02: drug-triggered/idiopathic pemphigus vulgaris, type 1 diabetes, SLE associated anti-cardiolipin and anti-β$_2$ glycoprotein I.
DRB1*04:03: polycystic ovary syndrome, SLE associated anti-cardiolipin and anti-β$_2$ glycoprotein I.
DRB1*04:04: anti-citrullinated fibrinogen in rheumatoid arthritis, autoimmune hepatitis.
DRB1*04:05: rheumatoid arthritis, Autoimmune hepatitis, type 1 diabetes.
DRB1*04:06: caspase-8 autoantibodies silicosis-systemic sclerosis (SSc)-systemic lupus erythematosus (SLE).
DRB1*04:09: T. cruzi infection with cardiomyopathy.

### By haplotype

DR4-DQ8 is a risk factor for papillary thyroid carcinoma, juvenile diabetes, coeliac disease and rheumatoid arthritis.
DRB1*04:DQA1*03:03-DQB1*04:01 haplotype: type III autoimmune polyglandular syndrome, autoimmune hepatitis, autoimmune pancreatitis.
DRB1*04:DQA1*03-DQB1*03:02 haplotype: Type 1 diabetes with DRB1*04:01, *04:05, *04:02 increasing risk when DQ8 is present.

### By genotype

DRB1*01:01/*04:04 and *01:01/*04:01 increases risk of mortality in rheumatoid arthritis, with ischemic heart disease and smoking. these same genotypes are associated with rheumatoid vasculitis.
# Habibullah Abdurazzaq

Habibullah Abdurazzaq (Tajik: Ҳабибуллоҳ Абдураззоқ) (7 November 1937 – 19 January 2021) was a Tajik actor and director of theater and cinema. He was a made a member of the Union of Cinematographers of the USSR in 1973.
# HMS Mediator (1745)

HMS Mediator was a 10-gun single-masted sloop of war of the Royal Navy, in service in American in 1745, during the War of the Austrian Succession. Built in Chesapeake Bay in 1741, she was purchased by the Navy four years later and sailed to Portsmouth for fitting out by Peirson Lock.
She was captured by a French privateer in June 1745, but recaptured the following day.
Mediator sprang a leak and foundered in Ostend harbor on 29 July 1745.

## Construction

Mediator was built as a private merchant vessel in early 1741, on the shore of Chesapeake Bay in the British colony of Virginia. She was a single-masted sloop with sloop-rigged sails, a 44 ft 0 in (13.4 m) keel and a substantial 21 ft 2 in (6.5 m) beam.
# HMS Meda (1880)

HMS Meda was a schooner of the Royal Navy, built by William Westacott Ship Building Company, Barnstaple and purchased by the Royal Navy in 1880.
She commenced service on the Australia Station in 1880 as a survey vessel for hydrographic surveys. She undertook survey work along North West Australia. The Meda River and Meda Passage are named after her. She was sold in 1887 to the Colony of Western Australia.

## Fate

She was sold to the Wesleyan Board of Missions in 1896. Meda was wrecked on a reef near East Cape, New Guinea on 14 June 1897.

## Citations

* 1 2 3 Bastock, p. 79.
* ↑ "The Sydney Morning Herald, Thursday 8 July 1897, p. 5". Sydney Morning Herald. 8 July 1897. Retrieved 23 October 2010.
# Ardoileán

Ardoileán or Ard Oileán, known in English as High Island (a translation of the Irish name), is a small island off the northwest coast of Connemara in County Galway, Ireland. It was once the site of an early Irish monastic community.

## Hermitage

It is one of thirty-odd islands off the west coast of Ireland, between Inishtrahull and Clear Island, which were settled by hermits and monastic communities in the early Christian period. Other such islands in the direct vicinity of Ardoiléan include Clare Island, Chapel Island, Caher Island, Inishturk, Inishbofin and Inishark. Since (at least) the seventh century, Ardoiléan had been the site of an early monastery or hermitage, reputedly founded by St Féchín of Fore (d. 665).
Above the south landing-place, near the remains of the monastery, there is a Christian cross-slab dating perhaps to the seventh century.

## Modern history

Between 1969 and 1998, the island was in the possession of Irish poet Richard Murphy, then a resident of Inishbofin. In personal memoirs published by Granta in The Kick (2002), Murphy remembers the opportunity when the previous owner considered selling the island: "I got excited at the thought of buying this inaccessible holy island, restoring the beehive cells and oratory of its derelict hermitage and preserving the place from destruction either by tourists or by sheep."
In February 2019, the island was put up for sale for €1.25 million by Spencer Auctioneers.
# HMS Turquoise

Four ships of the Royal Navy have been named HMS Turquoise.
* HMS Turquoise (1876), an Emerald-class corvette in service 1876–1892
* HMS Turquoise (1893), a fleet messenger sunk in the Atlantic by SM U-28 on 31 July 1915
* HMS Turquoise (1918), an S-class destroyer in service 1919–1928 and sold 1932
* HMS Turquoise (T45), a naval trawler, damaged on 31 August 1942 after colliding with the destroyer HMS Vanessa which lost control after an attack by German aircraft
# HMS Meon

HMS Meon was a River-class frigate that served with the Royal Navy and Royal Canadian Navy in the Second World War. The vessel was used primarily as a convoy escort in the Battle of the Atlantic, but also took part in the Invasion of Normandy. After the war, the ship was converted to a headquarters vessel for amphibious operations, and saw service in the Persian Gulf from 1952 to 1965, before being scrapped in 1966. She was named for the River Meon in the United Kingdom and was sponsored by the town of Bletchley in Buckinghamshire.
Meon was ordered on 24 January 1942. The ship was laid down on 31 December 1942 by A. & J. Inglis at Glasgow and launched 4 August 1943. She was commissioned into the Royal Navy on 31 December 1943.

## War service

After commissioning and trials, Meon sailed with convoy ON 220 to Canada. Once there she was recommissioned into the Royal Canadian Navy at Halifax, Nova Scotia on 7 February 1944. After working up with her new Canadian crew, she joined convoy escort group 9 in May 1944. Following the ship's arrival in Londonderry Port to join the group, the vessel spent until October 1944 in the waters around the United Kingdom. It was during this period that Meon participated in Operation Neptune, the sea component of the invasion of Normandy and was present on D-day.
Arriving at Halifax on 19 October 1944, Meon joined local convoy escort group 27 and was named Senior Officer's ship. She remained with the group until the end of March 1945, when the vessel returned to the United Kingdom and was handed back over to the Royal Navy at Southampton on 23 April 1945.

## Postwar service

Following return from the Canadians, Meon was converted at Southampton into a combined operations headquarters ship for use in South-East Asia. The ship's 4-inch guns were removed, as were the Hedgehog anti-submarine mortars, with armament reducing to three Bofors guns, allowing extra communications equipment and accommodation to be added. The conversion was completed in December 1945, and Meon was laid up in reserve at Harwich. After being used as an accommodation ship at Harwich, Meon, still in reserve, moved to Sheerness in 1949.
Meon recommissioned in April 1951, and in July 1952 was transferred to the Persian Gulf to serve as HQ ship for the Amphibious Warfare Squadron (Gulf). In 1953, back in British waters for a refit, Meon took part in the Fleet Review to celebrate the Coronation of Queen Elizabeth II. In 1956 Meon took part in the Suez Crisis, commanding landing craft during Operation Musketeer. In late June 1961, in response to Iraqi threats to annex Kuwait, Meon took part in Operation Vantage, helping landings of British troops and equipment in Kuwait. The vessel remained in the Gulf until 1965. The ship was laid up at Portsmouth until being sold to Hughes Bolckow Ltd and being broken up at Blyth, Northumberland from 14 May 1966.
# Hacıahmetlitepeköy, Ağaçören

Hacıahmetlitepeköy is a village in the Ağaçören District, Aksaray Province, Turkey. Its population is 170 (2021).
# Seric

Seric is a South Slavic surname. Notable people with the surname include:
* Anthony Šerić (born 1979), Australia-born Croatian soccer player
* Andrea Šerić (born 1985), Croatian handball player
# Arghavan

Arghavan (Persian: ارغوان, also Romanized as Arghavān) is a village in Jowzam Rural District, Dehaj District, Shahr-e Babak County, Kerman Province, Iran. At the 2006 census, its population was 15 distributed in 8 families.
# Himayatnagar taluka

Himayatnagar taluka is a taluka in Nanded district in the state of Maharashtra, India.

## Demographics

Religions in Himayatnagar taluk (2011) :
| Religion | Religion | Percent | Percent |
| Hinduism | Hinduism | 77.01% | 77.01% |
| Islam | Islam | 11.89% | 11.89% |
| Buddhism | Buddhism | 10.33% | 10.33% |
| Other or not stated | Other or not stated | 0.77% | 0.77% |
At the time of the 2011 census, Himayatnagar taluk had 22,669 households and a population of 109,727. Himayatnagar taluk had a sex ratio of 948 females per 1000 males and a literacy rate of 72.48%. 16,339 (14.89%) were under 6 years of age. Scheduled Castes and Scheduled Tribes made up 13.73% and 16.89% of the population respectively.
Languages of Himayatnagar taluk (2011)
At the time of the 2011 census, 79.25% of the population spoke Marathi, 8.38% Urdu, 7.83% Lambadi and 3.45% Hindi as their first language.
# Hantsambou

Hantsambou is a village on the island of Grande Comore (Ngazidja) in the Comoros. According to the 1991 census, the village had a population of 1015.
# G0711 Ürümqi–Ruoqiang Expressway

The G0711 Ürümqi–Ruoqiang Expressway (Chinese: 乌鲁木齐至若羌高速公路), also referred to as the Wuruo Expressway (Chinese: 乌若高速公路), is an expressway in Xinjiang, China that connects Ürümqi to Ruoqiang County.

## Route

The expressway starts in Saybag District, Ürümqi, then passes through Korla and Yuli County along the eastern part of the Taklimakan Desert to Ruoqiang County.
# Uganda at the 1972 Summer Paralympics

Uganda made its Paralympic Games début at the 1972 Summer Paralympics in Heidelberg, West Germany - shortly after Idi Amin's rise to power.

## Background

Uganda made their Paralympic debut at the 1972 Summer Paralympics in Heidelberg, West Germany.

## Team

Uganda sent a two sportspeople strong delegation to the Games.

## Athletics

The country entered only two athletes, who both competed in men's javelin and shot put. Neither of them won a medal.
# USS Urdaneta

USS Urdaneta – occasionally misspelled Undaneta – was an iron-hulled gunboat in the United States Navy. She was named for Spanish friar and explorer Andres de Urdaneta.
Urdaneta was built for the Spanish government at the Cavite Arsenal near Manila, Philippines, in 1882 and 1883 and was apparently captured by the United States Army during the Spanish–American War in 1898. Acquired from the War Department by the Navy on 17 January 1899, Urdaneta went into commission on 2 June 1899.

## Service history

The gunboat conducted local patrols into the summer months to interdict the flow of munitions and arms to the opposition during the Philippine–American War. On 17 September 1899, Urdaneta ran aground in the Orani River, near Manila, on a soft mud shoal. Insurrectionists along the river soon opened a withering enfilading fire, killing the gunboat's commanding officer, Naval Cadet Welborn C. Wood, and some of his crew.
Urdaneta resumed her service in the spring of the following year, being commissioned at Cavite on 12 May 1900. She departed Cavite on the 14th and served for a time as guard ship at Olongapo before shifting to Subic, and eventually, to Cavite, where she spent the remainder of May undergoing repairs and alterations.
Urdaneta subsequently operated as guard vessel at Subic Bay and conducted surveys in connection with the impending visits of the commission investigating naval base sites in the Philippines. She remained engaged in these vital but unglamourous duties until she was decommissioned on 12 December 1902 at Cavite. Struck from the Navy list on 15 December 1904, Urdaneta was apparently reinstated on the Navy list as a tug, although there is no extant record of this event. The ship is listed in Ship's Data, United States Naval Vessels editions for 1912 through 1916 as a yard tug operating at Cavite. Her subsequent fate is unknown.
# Victoria Daly Regional Council

The Victoria Daly Regional Council is a local government area in the Northern Territory of Australia. The shire covers an area of 153,287 square kilometres (59,184 sq mi) and had a population of 3,138 in June 2018.

## History

In October 2006 the Northern Territory Government announced the reform of local government areas. The intention of the reform was to improve and expand the delivery of services to towns and communities across the Northern Territory by establishing eleven new shires. The Victoria Daly Shire was created on 1 July 2008 as were the remaining ten shires. The first election for the Shire was held on 25 October 2008.
The Shire became the Victoria Daly Region on 1 January 2014.
Most of the land now part of the Region used to be unincorporated, but several existing LGAs were merged into it:
* Daguragu Community
* Nauiyu Nambiyu Community
* Timber Creek Community
* Walangeri Ngumpinku Community
* Pine Creek Community
* Woolianna Community
On 1 July 2014, the boundaries on its west side were revised to create a new local government area called the West Daly Region which consisted of the following three wards from the Victoria Daly Region - Nganmarriyanga, Thamarrurr/Pindi Pindi and Tyemirri.
A general election was held in September 2017. Councillor Brian Pedwell was elected Mayor of Victoria Daly Regional Council.

## Wards

The Victoria Daly Regional Council is divided into 5 wards, which is governed by 5 councillors:
* Pine Creek (1)
* Milngin (1)
* Timber Creek (1)
* Walangeri (1)
* Daguragu (1)

## Localities and communities

Land within the Victoria Daly Shire was divided in 2007 into bounded areas for the purpose of creating an address for a property. Most bounded areas are called "localities" while those associated with aboriginal communities are called "communities".

### Communities

| Community | Population |
| Daguragu | 196 (SAL 2021) |
| Kalkarindji | 383 (SAL 2021) |
| Nauiyu | 350 (SAL 2021) |
| Pigeon Hole | 121 (SAL 2021) |
| Yarralin (Walangeri) | 283 (SAL 2021) |

### Localities

* Baines
* Bradshaw
* Buchanan
* Burrundie
* Claravale
* Daly River
* Delamere
* Douglas-Daly (part)
* Edith
* Fleming
* Gregory
* Gurindji (part)
* Maranunga
* Nemarluk (part)
* Pine Creek
* Timber Creek
* Tipperary
* Top Springs
* Victoria River
# 2023 Georgia's Rome Tennis Open – Doubles

Sophie Chang and Angela Kulikov were the defending champions but Kulikov chose not to participate. Chang partnered alongside Kayla Day, but lost to Beatrice Gumulya and Hsieh Yu-chieh in the quarterfinals.
Fanny Stollár and Lulu Sun won the title, defeating Mana Ayukawa and Gabriela Knutson in the final, 6–3, 6–0.

## Seeds

* Arianne Hartono / Eva Vedder (first round)
* Beatrice Gumulya / Hsieh Yu-chieh (semifinals)
* Francesca Di Lorenzo / Marcela Zacarías (first round)
* Irene Burillo Escorihuela / Andrea Lázaro García (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking
| First round | First round | First round | First round | First round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| 1 | A Hartono E Vedder | 3 | 3 | | | | | | | | | | | | | |
| | M Kozyreva A Lahey | 6 | 6 | | | M Kozyreva A Lahey | w/o | | | | | | | | | |
| | R Anderson M Mateas | 6 | 6 | | | R Anderson M Mateas | | | | | | | | | | |
| WC | S Daavettila M Kononova | 4 | 4 | | | | | | | | M Kozyreva A Lahey | 5 | 5 | | | |
| 4 | I Burillo Escorihuela A Lázaro García | 3 | 7 | [8] | | | | | | | M Ayukawa G Knutson | 7 | 7 | | | |
| | P Marčinko J Svendsen | 6 | 5 | [10] | | P Marčinko J Svendsen | 4 | 2 | | | | | | | | |
| | A Zamarripa M Zamarripa | 1 | 2 | | | M Ayukawa G Knutson | 6 | 6 | | | | | | | | |
| | M Ayukawa G Knutson | 6 | 6 | | | | | | | | | | | M Ayukawa G Knutson | 3 | 0 |
| WC | K Cross K Hui | 3 | 5 | | | | | | | | | | | F Stollár L Sun | 6 | 6 |
| | F Stollár L Sun | 6 | 7 | | | F Stollár L Sun | 7$^7$ | 7$^7$ | | | | | | | | |
| | D Hewitt K Jokić | 6 | 7$^7$ | | | D Hewitt K Jokić | 6$^1$ | 6$^5$ | | | | | | | | |
| 3 | F Di Lorenzo M Zacarías | 4 | 6$^3$ | | | | | | | | F Stollár L Sun | 7 | 6 | | | |
| | S Chang K Day | 6 | 6 | | | | | | | 2 | B Gumulya Y-c Hsieh | 5 | 3 | | | |
| | H Arakawa N Arakawa | 0 | 0 | | | S Chang K Day | 7 | 4 | [8] | | | | | | | |
| WC | G Price K Shaffer | 4 | 4 | | 2 | B Gumulya Y-c Hsieh | 5 | 6 | [10] | | | | | | | |
| 2 | B Gumulya Y-c Hsieh | 6 | 6 | | | | | | | | | | | | | |
# Victoria Hospital, Rothesay

Victoria Hospital is a health facility in High Street, Rothesay, Scotland. It is managed by NHS Highland.

## History

The facility has its origins in the Robertson Stewart Hospital for infectious diseases which opened in 1873. A new hospital, which was designed by John Russell Thomson, was built adjacent to the original facility and opened as the Victoria Cottage Hospital in 1897. It was extended in 1927 and, after joining the National Health Service in 1948, it was re-organised to create a dedicated palliative care area in 2018.
# Grand Canyon (1949 film)

Grand Canyon is a 1949 American Western film starring Richard Arlen. It was the directorial debut of veteran editor Robert Landres and was financed by Robert L. Lippert. It was shot at the Nassour Studios.
Lippert assigned Carl Hittleman to produce the film after the success of I Shot Jesse James.
# Vinelli

Vinelli is a surname. Notable people with the surname include:
* Felice Vinelli (1774–1825),Italian painter
* Paul Vinelli (1922–1997), Italian-American-Honduran economist
# Victorino

Victorino is both a given name and a surname. Notable people with the name include:

## Surname

* Cesáreo Victorino (born 1979), Mexican footballer
* Mauricio Victorino (born 1982), Uruguayan football defender
* Mike Victorino (born 1952), Mayor of Maui County, father of Shane Victorino
* Shane Victorino (born 1980), American baseball outfielder, son of Mike Victorino
* Waldemar Victorino (born 1952), Uruguayan football forward

## Given name

* Victorino Chua, Stepping Hill nurse found guilty of eating murdering patients
* Victorino Abente y Lago (1846 - 1935) Paraguayan poet
* Victorino de la Plaza (1840 - 1919), President of Argentina
* Victorino Mapa (1855 - 1927), Philippines Chief of Justice
* Victorino Márquez Bustillos, President of Venezuela
# Villa Carlotta (Los Angeles County)

Villa Carlotta is the name of two landmark buildings in greater Los Angeles, California.

## Altadena

Villa Carlotta is a 7,000-square-foot Mission Revival-style house at 234 East Mendocino Street in Altadena, California. It was listed on the National Register of Historic Places in 2014. Completed in 1917, it was one of the first houses in Altadena in which electrical wiring was incorporated into the original architectural plans.
The house was built by Francis Raymond Welles, who hired architect Myron Hunt. Hunt incorporated features of the Welles' family estate in France in the plans for Villa Carlotta, as evidenced by the house's high ceilings and tall windows. It remains a private house.

## Franklin Village

Villa Carlotta is a 50-unit Spanish Colonial-style apartment house at 5959 Franklin Avenue in the Franklin Village neighborhood of Hollywood, California. It was built in 1926 for the widow of Thomas H. Ince and designated a Los Angeles historical cultural monument in 1986.
The four-story building was designed by Arthur E. Harvey, who also designed the nearby Château Élysée.
The building's notable tenants include actor Edward G. Robinson, actress Marion Davies, writer William Saroyan, film producer David O. Selznick, and architect Wallace Neff. Louella Parsons wrote her gossip column from her two-story apartment in the building.
The Lesser family trust owned the building from the 1950s to 2014, when it was bought by investment firm CGI Strategies. Gidi Cohen and Adrian Goldstein of CGI Strategies are committed to restoring and renovating the historic building with a focus on preserving its architectural heritage, including keeping and refreshing the features and fixtures that made it a special place for residents and visitors. The renovation work allow for the building to be shared by the entire community. In 2018, Villa Carlotta and CGI Strategies received the California Preservation Design Award.
It took CGI Strategies two years to restore Villa Carlotta. They carefully painted stenciled wood beams and coffered ceilings by hand and preserved much of the original wood, stone, and marble. CGI Strategies' restoration retained Villa Carlotta's original 1926 contractor to fabricate and install new exterior awnings.