# 2021 Cleveland Open – Singles

Mikael Torpegaard was the defending champion but lost in the first round to Lucas Catarina.
Bjorn Fratangelo won the title after defeating Jenson Brooksby 7–5, 6–4 in the final.

## Seeds

* James Duckworth (first round)
* Go Soeda (first round)
* Emilio Gómez (semifinals)
* Mikael Torpegaard (first round)
* Mitchell Krueger (first round)
* Brayden Schnur (second round)
* Thai-Son Kwiatkowski (first round)
* Roberto Cid Subervi (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| | Jenson Brooksby | 2 | 7 | 6 | | | |
| 3 | Emilio Gómez | 6 | 5 | 4 | | | |
| 3 | Emilio Gómez | 6 | 5 | 4 | Jenson Brooksby | 5 | 4 |
| | | | | | Bjorn Fratangelo | 7 | 6 |
| Q | Aleksandar Kovacevic | 3 | 6 | 1 | Bjorn Fratangelo | 7 | 6 |
| | Bjorn Fratangelo | 6 | 2 | 6 | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | J Duckworth | 6$^{11}$ | 1 | | | | | | | | | | | | | | | |
| | Mi Redlicki | 7$^{13}$ | 6 | | | Mi Redlicki | 6 | 6 | | | | | | | | | | |
| WC | L Draxl | 7$^8$ | 6 | | WC | L Draxl | 3 | 3 | | | | | | | | | | |
| | R Quiroz | 6$^6$ | 4 | | | | | | | | Mi Redlicki | 6$^5$ | 4 | | | | | |
| | J Brooksby | 7$^7$ | 7$^7$ | | | | | | | | J Brooksby | 7$^7$ | 6 | | | | | |
| WC | Z Svajda | 6$^4$ | 6$^5$ | | | J Brooksby | 6 | 7$^7$ | | | | | | | | | | |
| Q | Felix Corwin | 6$^0$ | 6$^4$ | | 6 | B Schnur | 2 | 6$^5$ | | | | | | | | | | |
| 6 | B Schnur | 7$^7$ | 7$^7$ | | | | | | | | | | | | J Brooksby | 2 | 7 | 6 |
| 3 | E Gómez | 6 | 6 | | | | | | | | | | | 3 | E Gómez | 6 | 5 | 4 |
| Alt | E King | 4 | 2 | | 3 | E Gómez | 1 | 7$^7$ | 6 | | | | | | | | | |
| Alt | N Mejía | 6 | 4 | 6 | Alt | N Mejía | 6 | 6$^4$ | 1 | | | | | | | | | |
| Q | Evan Song | 3 | 6 | 3 | | | | | | 3 | E Gómez | 6 | 6 | | | | | |
| | H Moriya | 6 | 4 | 2 | | | | | | | C Eubanks | 3 | 3 | | | | | |
| | C Eubanks | 4 | 6 | 6 | | C Eubanks | 6 | 6 | | | | | | | | | | |
| | D King | 6 | 5 | 7 | | D King | 1 | 2 | | | | | | | | | | |
| 5 | M Krueger | 3 | 7 | 5 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | R Cid Subervi | 2 | 4 | | | | | | | | | | | | | | | | |
| Q | A Kovacevic | 6 | 6 | | Q | A Kovacevic | 7$^7$ | 6 | | | | | | | | | | | |
| | N Chappell | 4 | 7 | 4 | WC | R Smith | 6$^4$ | 3 | | | | | | | | | | | |
| WC | Roy Smith | 6 | 5 | 6 | | | | | | Q | A Kovacevic | 5 | 6 | 6 | | | | | |
| | K King | 4 | 6$^1$ | | | | | | | | Yo Watanuki | 7 | 2 | 3 | | | | | |
| | Yo Watanuki | 6 | 7$^7$ | | | Yo Watanuki | 6 | 5 | 6 | | | | | | | | | | |
| Alt | L Catarina | 5 | 6 | 6 | Alt | L Catarina | 3 | 7 | 1 | | | | | | | | | | |
| 4 | M Torpegaard | 7 | 3 | 4 | | | | | | | | | | | Q | A Kovacevic | 3 | 6 | 1 |
| 7 | T-S Kwiatkowski | 4 | 2 | | | | | | | | | | | | | B Fratangelo | 6 | 2 | 6 |
| | B Fratangelo | 6 | 6 | | | B Fratangelo | 6 | 6 | | | | | | | | | | | |
| | A Ritschard | 7$^7$ | 5 | 7 | | A Ritschard | 3 | 2 | | | | | | | | | | | |
| | JC Aragone | 6$^5$ | 7 | 5 | | | | | | | B Fratangelo | 6 | 5 | | | | | | |
| Q | A Galarneau | 6 | 6 | | | | | | | Q | A Galarneau | 3 | 0$^r$ | | | | | | |
| | Shuichi Sekiguchi | 3 | 1 | | Q | A Galarneau | 7 | 7 | | | | | | | | | | | |
| | D Young | 6 | 6$^5$ | 7 | | D Young | 5 | 5 | | | | | | | | | | | |
| 2 | G Soeda | 3 | 7$^7$ | 5 | | | | | | | | | | | | | | | |