# 2022 Rancho Santa Fe Open – Singles

Rebecca Peterson was the defending champion but withdrew before her first round match.
Marcela Zacarías won the title, defeating Katrina Scott in the final, 6–1, 6–2.

## Seeds

* Rebecca Peterson (withdrew)
* Yuan Yue (first round)
* Katie Volynets (second round)
* Nao Hibino (quarterfinals)
* Caroline Dolehide (first round)
* Katarzyna Kawa (first round)
* Carol Zhao (first round)
* Arianne Hartono (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| | Marcela Zacarías | 3 | 7$^7$ | 6 | | | |
| WC | Elvina Kalieva | 6 | 6$^5$ | 4 | | | |
| WC | Elvina Kalieva | 6 | 6$^5$ | 4 | Marcela Zacarías | 6 | 6 |
| | | | | | Katrina Scott | 1 | 2 |
| | Katrina Scott | 6 | 7$^7$ | | Katrina Scott | 1 | 2 |
| Q | Storm Sanders | 3 | 6$^5$ | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| LL | A Reami | 7 | 2 | 5 | | | | | | | | | | | | | | |
| Q | H Inoue | 5 | 6 | 7 | Q | H Inoue | 1 | 5 | | | | | | | | | | |
| | W Osuigwe | 3 | 3 | | | M Zacarías | 6 | 7 | | | | | | | | | | |
| | M Zacarías | 6 | 6 | | | | | | | | M Zacarías | 6 | 7 | | | | | |
| WC | D Hewitt | 1 | 6 | 0 | | | | | | Q | A Eala | 2 | 5 | | | | | |
| Q | A Eala | 6 | 2 | 6 | Q | A Eala | 7$^8$ | 6 | | | | | | | | | | |
| | K Sebov | 4 | 7$^7$ | 6 | | K Sebov | 6$^6$ | 2 | | | | | | | | | | |
| 7 | C Zhao | 6 | 6$^5$ | 2 | | | | | | | | | | | M Zacarías | 3 | 7$^7$ | 6 |
| 3 | K Volynets | 6 | 5 | 6 | | | | | | | | | | WC | E Kalieva | 6 | 6$^5$ | 4 |
| | A Sharma | 2 | 7 | 4 | 3 | K Volynets | 4 | 6 | 1 | | | | | | | | | |
| | D Shnaider | 6 | 6 | | | D Shnaider | 6 | 2 | 6 | | | | | | | | | |
| Q | A Rogers | 2 | 4 | | | | | | | | D Shnaider | 0 | 3 | | | | | |
| | C Harrison | 4 | 6$^3$ | | | | | | | WC | E Kalieva | 6 | 6 | | | | | |
| SE | R Montgomery | 6 | 7$^7$ | | SE | R Montgomery | 2 | 6 | 6$^1$ | | | | | | | | | |
| WC | E Kalieva | 6 | 7 | | WC | E Kalieva | 6 | 2 | 7$^7$ | | | | | | | | | |
| 5 | C Dolehide | 4 | 5 | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | A Hartono | 6 | 6 | | | | | | | | | | | | | | |
| Q | C-y Hsu | 4 | 2 | 8 | A Hartono | 5 | 4 | | | | | | | | | | |
| Q | E Perez | 2 | 6$^6$ | | K Scott | 7 | 6 | | | | | | | | | | |
| | K Scott | 6 | 7$^8$ | | | | | | | K Scott | 2 | 7 | 6 | | | | |
| | D Lao | 6 | 6 | | | | | | 4 | N Hibino | 6 | 5 | 2 | | | | |
| | R Zarazúa | 2 | 4 | | D Lao | 3 | 5 | | | | | | | | | | |
| WC | J Tjen | 2 | 2 | 4 | N Hibino | 6 | 7 | | | | | | | | | | |
| 4 | N Hibino | 6 | 6 | | | | | | | | | | | | K Scott | 6 | 7$^7$ |
| 6 | K Kawa | 4 | 3 | | | | | | | | | | | Q | S Sanders | 3 | 6$^5$ |
| | A Krueger | 6 | 6 | | A Krueger | 6 | 7$^7$ | | | | | | | | | | |
| | S Chang | 6 | 6 | | S Chang | 3 | 6$^3$ | | | | | | | | | | |
| Q | E Shibahara | 1 | 4 | | | | | | | A Krueger | 2 | 3 | | | | | |
| Q | U Radwańska | 2 | 0 | | | | | | Q | S Sanders | 6 | 6 | | | | | |
| Q | S Sanders | 6 | 6 | Q | S Sanders | 6 | 6$^3$ | 6 | | | | | | | | | |
| | L Chirico | 6 | 6 | | L Chirico | 1 | 7$^7$ | 0 | | | | | | | | | |
| 2 | Y Yuan | 4 | 1 | | | | | | | | | | | | | | |