OpenLLM-France/wikimedia huggingface dataset:
# Multinucleate cell angiohistiocytoma

Multinucleate cell angiohistiocytoma (MCAH) is a cutaneous condition that presents as slowly growing, multiple, discrete but grouped, red to violaceous papules

## Signs and symptoms

Lesions are asymptomatic and most commonly found on the face and acral regions, however they have been described in other locations such as the trunk and, less frequently, the mucous membranes; they are usually unilateral and appear as papules ranging in diameter from 2 to 15mm.
They can be smooth and flat, or they can seem like reddish, pink, violaceous, or brown papules with a slightly elevated dome-shaped surface. There have been a few cases reported with bilateral involvement and even widespread forms. MCAH lesions do not seem to spontaneously remit; instead, they grow over weeks to months.

## Causes

While there are still many unanswered questions regarding the etiology and pathogenesis of MCAH, the general consensus is that lesions result from a reactive process rather than a neoplastic one.

## Mechanism

This disease is thought to be caused by enhanced cutaneous vascularity and an aggressive inflammatory response to intravascular macrophage migration. Furthermore, impacted regions demonstrate an overabundance of estrogen receptor α. Angiogenesis has been associated with estrogen signaling. This discovery may help to explain why MCAH is more common in women and why it is extremely vascular.

## Diagnosis

Histopathologically, multinucleated cells with angular outlines in the dermis and vascular hyperplasia linked to a rise in factor XIIIa-positive fibrohistiocytic interstitial cells are the hallmarks of MCAH. The most specific histological finding (3–10 hyperchromatic nuclei with basophilic cytoplasm) is the presence of multinucleated giant cells, albeit this finding does not necessarily indicate the presence of MCAH.
Immunohistochemistry demonstrates that vascular endothelial cells are positive for Factor VIII, vimentin, CD31, and CD34 antibodies, but negative for Bcl-2 and HHV-8 antigens. Vimentin, Factor XIIIa, CD68, alpha-1-antitrypsin, and lysozyme are expressed by mononuclear cells, although neither S100 nor CD1a are. The MAC387 expression is not constant. While multinucleate cells are negative for other monocyte/macrophage lineage markers, they are significantly positive for vimentin. CD68 expression can be either positive or negative. In interstitial and perivascular spindle cells, as well as rarely in multinucleate cells, estrogen receptor α has significant expression.
Angiofibroma/fibrous papule, dermatofibroma, microvenular hemangioma, Kaposi's sarcoma, and acroangiodermatitis are among the histopathologic differential diagnoses.

## Treatment

Treatment is not required because the lesion is benign, but it might be suggested for itchy or unappealing lesions. The literature has reported on a number of treatment approaches, such as intense pulsed light, cryosurgery, corticosteroids, argon and carbon dioxide lasers, and surgical excision.
# Cocks & Féret

Cocks & Féret or simply Féret, is the colloquial name of a Bordeaux wine directory originally created by Charles Cocks and Michel-Édouard Féret in 1846, which was published under the name Bordeaux, its Wines and the Claret Country and translated into French and published as the first edition of Bordeaux et ses vins in 1850. It is regarded as the classic reference work on Bordeaux wines, and is to date considered the most comprehensive information source on Bordeaux' wineries.

## History

Jean-Baptiste Féret founded the publishing house La Librairie Féret in Bordeaux in 1812, which became Féret et fils in 1841. In 1846 Michel-Édouard Féret approached Charles Cocks, an English schoolmaster and wine enthusiast living in Bordeaux since 1840, to publish a directory of wine aimed at his compatriots. At 84 pages containing historical observations and assessment of Bordeaux wine, Bordeaux, its Wines and the Claret Country was published in London that year.
It was not the first publication dealing solely with Bordeaux wines however, in many ways its forerunner is cited as Traite sur les vins du Medoc (1824) by William Franck.
A French translation was proposed by Féret, which led to Guide de l'étranger à Bordeaux et dans la Gironde. Bordeaux, ses environs et ses vins classés par ordre de mérite published in 1850, with further emphasis on classifying wines in order of merit. This directory would be considered the first edition of Bordeaux et ses Vins.
Charles Cocks died in 1854, while the second edition, Bordeaux et ses Vins 2ème édition, appeared in 1868, and the succession of publications provide a useful historical record of the evolution of different properties' and districts' reputations.
Revisions are published to date, usually referred to as "Le Féret", most recently with the 2007 edition of Bordeaux et ses Vins 18ème édition. The English language translations are titled Bordeaux and Its Wines, with the seventeenth edition published in 2004.

## Early classification

Nearly a decade before the Bordeaux Wine Official Classification of 1855, Cocks assessed Château Lafite, Château Latour, Château Margaux and Château Haut-Brion as First Growths, while ranking as Second Growths Château Mouton, Château Léoville (present day Château Léoville-Las Cases, Château Léoville-Poyferré and Château Léoville Barton) Château Rauzan (present day Château Rauzan-Ségla and Château Rauzan-Gassies), Château Durfort, Château Gruaud-Larose, Château Lascombes and Château Gorse (present day Château Brane-Cantenac).
# Mauroniscidae

Mauroniscidae is a family of cleroid beetles, formerly included in the family Melyridae. There are presently five or six genera and roughly 30 described species in Mauroniscidae, all of which are native to the Americas. Almost nothing is known about their biology.

## Genera

* Amecomycter Majer, 1995
* Mauroniscus Bourgeois, 1911
* Mecomycter Horn, 1882
* Mectemycor Majer, 1995
* Scuromanius Majer, 1995

### Incertae sedis in Mauroniscidae

* Dasyrhadus Fall, 1910
# Chasm (song)

"Chasm" is the fourth single by Flyleaf from their second album, Memento Mori. The song was officially available for digital download on September 27, 2010.

## Content

Chasm is based on the New Testament parable of The Rich Man and Lazarus. In the parable, the rich man dies and goes to hell. From hell, he looks up to Heaven and sees Lazarus, a beggar who had scrounged crumbs from underneath his table, sitting next to the Jewish patriarch Abraham. The rich man begs Abraham to allow Lazarus to dip his finger in water and come down to hell to soothe his burning tongue. This is impossible because of a wide chasm between Heaven and hell. The rich man then begs Abraham to send Lazarus back to Earth to warn the rich man's brothers to follow the Law of God so that they won't end up next to him in hell. This request is also denied. Abraham responds that his brothers have the words of Moses and the prophets. If they won't believe Moses or the prophets, they won't believe Lazarus even if he returns from the dead.

## Music video

Giles Timms directed, animated and illustrated the animated music video for Chasm. The music video premiered on Vevo on September 22, 2010.

## Letters from the Commander/History of Memento Mori

3.16.01 Chasm (third part of the History of Memento Mori)
While the enemy was losing the battle today, they cried out to us, "Memento Mori, we are human too! We are in pain and we are dying!". I answered them, hoping they would listen, "Break off your pact with the Dread Army! That is what is killing you! Walk away and take your life back! I know it's all you've ever known, and walking away will leave a wound, but it will heal! When it does, do not enter into your pact with the vultures again! You don't have to be slaves to death! We've come to bring the truth of freedom! You were meant to be free!" But they wouldn't listen and kept crying out, "Please give me something! I'm so thirsty." I tried again with more urgency. "If you die here this way, you will have wasted your life on death and you will have never lived! Once you die here, the chasm will be fixed and you can never undo it. Turn from death and drink this life-giving water we are offering you!" The battle continued to rage, some turning and joining the Passerby Army, others dying.

## Chart performance

| Chart (2010) | Peak position |
| US Mainstream Rock Songs (Billboard) | 26 |
| US Rock Songs (Billboard) | 48 |
# CAR-226,086

CAR-226,086 is a potent anticholinergic deliriant drug with a fairly long duration of action, related to the chemical warfare agent 3-quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program, during research to improve upon the properties of earlier agents such as QNB.
CAR-226,086 was relatively poorly researched compared to other compounds in the series, but notably was found to have the highest central to peripheral effects ratio out of all compounds tested, even higher than that of other CNS-selective agents such as EA-3443.
# Magnapinna sp. C

Magnapinna sp. C is an undescribed species of bigfin squid known only from a single specimen of 79-millimetre (3.1 in) mantle length (ML) collected in the southern Atlantic Ocean and held in the Natural History Museum.

## Description

It is characterised by several morphological features: the proximal tentacles are more slender than arm pair IV, pigmentation is contained in the chromatophores, and "white nodules" are absent from the fins and glandular regions of the proximal tentacles.

## Taxonomy

Magnapinna sp. C was originally illustrated in The Open Sea in 1956 and identified as Octopodoteuthopsis.
# Maguindanao (disambiguation)

Maguindanao may refer to:
* Maguindanao, a former province of the Philippines currently partitioned into :
** Maguindanao del Norte, province
** Maguindanao del Sur, province
* Maguindanao people, in the Philippines
** Maguindanao language, their Austronesian language
* Sultanate of Maguindanao, a former sultanate in the province
* Maguindanao massacre
# Mahl (surname)

Mahl is a surname. Notable people with the surname include:
* Claire Mahl Moore (1912–1988), American artist
* Emil Mahl (1899–1967)
* Evald Mahl (1915–2001), Estonian basketball player
* Victor Mahl (1889–1915), English aviator
# Mahla

Mahla may refer to:
* Mahla (short film), a 2009 short film
* Mahla Lake, a lake in Douglas County, Minnesota, US
* Mahla Momenzadeh (born 2002), Iranian Taekwondo athlete
* Mahla Pearlman (1937–2011), Australian lawyer and chief judge of the Land and Environment Court of New South Wales
* Mahla Zamani, Iranian fashion designer
# Magika

Magika is a 2010 Malaysian Malay-language musical adventure fantasy film directed by Edry Abdul Halim starring Diana Danielle, Mawi and Fimie Don.

## Plot

Ayu and Malik, two siblings are going through their darkest moments of lives when their beloved mother just died. Malik feels so depressed believing that he was the main cause of his mother's death. During one of the evenings after a fight with his sister, Malik left to take a stroll in the forest. On and on he went until he realised he was lost and the next very moment, he appeared in another dimension called Magika.
Not only had he gotten himself lost, he was captured by a Nenek Kebayan and her follower, Awang Kenit. He is now subjected to be used as an experiment by the Nenek Kebayan to produce Essence of Youth made of human child's tears. Upon hearing Malik's cries for help, Ayu rushed to help her brother and she too is sucked in the Magika mystical land.
Ayu had to endure various types of challenges and obstacles to find and save her brother in her journey in the Magika world. And so begins the encounters of both the siblings with famous Malay heroes and myths like Badang, Dragon of Chini Lake, Nenek Kebayan, Puteri Bunian, Pak Pandir, Hang Tuah and the Warriors of Malacca, Mount Ledang Princess, Bawang Putih and a lot more characters, all of whom communicate with each other in song.

## Cast

* Diana Danielle as Ayu
* Mawi as Bad
* Fimie Don as Malik
* Ziana Zain as Nenek Kebayan
* Ning Baizura as Puteri Gunung Ledang
* Maya Karin as Bunian
* Raja Azura as Mak Andeh
* Norman Abdul Halim as Pokok Bersaudara 1
* Edry Abdul Halim as Pokok Bersaudara 2
* Yusry Abdul Halim as Pokok Bersaudara 3
* Aznil Nawawi as Pak Pandir
* M. Nasir as the Chini Lake dragon
* Jalaluddin Hassan as Murad
* Ogy Ahmad Daud as Ija
* Sharifah Amani as Bawang Putih
* Sharifah Aleya as Bawang Merah
* Adibah Noor as Makcik Halia
* Ruminah Sidek as Tok Wan
* Sabri Yunus as the Bendahara
* Saiful Apek as Hang Tuah
* Lan Pet Pet as Hang Jebat
* Azlee Jaafar as Hang Kasturi
* Hamdan Ramli as Hang Lekir
* Ilya Buang as Hang Lekiu
* Vanida Imran as Mahsuri
* Norman Hakim as Awang Lembing
* Nabil Ahmad as Orang Minyak
* Zaibo as Pak Belalang
* Hadziq as Belalang
* Marsha Milan Londoh as Puteri Santubong
* Azhari Zain as the Doctor
# Maida Clark

Maida Jessie Clark QSO JP (5 November 1902 – 31 May 1991) was a New Zealand educator, politician, and community leader. She served as principal of Wellington Girls' College between 1950 and 1958, and was a Wellington city councillor from 1959 to 1968.

## Early life and family

Clark was born in Wellington on 5 November 1902, the daughter of Jessie and Donald George Clark. She was educated at Wellington Girls' College, and went on to study history at Victoria University College, graduating with a Master of Arts degree with second-class honours in 1925.

## Teaching career

Clark became a schoolteacher, and worked at New Plymouth Girls' High School, Auckland Girls' Grammar School, and Napier Girls' High School, as well as gaining experience teaching in England. She became headmistress of Wellington Girls' College, serving in that role from 1950 to 1958.

## Political and other activities

At the 1959 local-body elections, Clark was elected under the banner of the Wellington Citizens' Association as a member of the Wellington City Council, polling fifth out of 46 candidates. She was re-elected at the next two elections, serving as a city councillor until 1968. She was a member of the city council's housing allocation committee, and represented the council on the state housing allocation committee.
In August 1960, Clark was selected as the National Party's candidate for the Onslow electorate at that year's general election. Standing against the Labour incumbent, Henry May, Clark gained 7880 votes, losing to May by 790 votes.
Clark was appointed to the Cinematograph Films Censorship Board of Appeal by Leon Götz, Minister of Internal Affairs, in 1962, serving until 1974. During her tenure, significant rulings in which Clark was involved include overturning the chief censor's ban on The Knack ...and How to Get It in 1966, and upholding the censor's decisions not to allow My Lover, My Son (1970), What Do You Say to a Naked Lady? (1972), and Last Tango in Paris (1973) to be screened in New Zealand. In the case of Last Tango in Paris, the review body's decision was not unanimous, but Clark agreed with the majority decision to ban the film.
From 1962 to 1963, Clark served as president of the New Zealand Library Association. Between 1962 and 1974, she was a member of the Golden Kiwi distribution committee for youth and recreation matters. She was also active in sports administration, serving as patron of the Wellington Women's Cricket Association in 1961, vice president of the New Zealand Women's Hockey Association, and patron of the Wellington Women's Hockey Association. From 1950 to 1960, Clark was president of the Wellington YWCA board of directors, and she was president of Ohariu Golf Club in 1963.

## Later life and death

In the 1975 Queen's Birthday Honours, Clark was appointed a Companion of the Queen's Service Order, for services to education and the community. She died in Lower Hutt on 31 May 1991, at the age of 88.
# COMC

COMC may refer to:
* Canadian Open Mathematics Challenge, competition
* L-2-hydroxycarboxylate dehydrogenase (NAD+), enzyme
* (2R)-3-sulfolactate dehydrogenase (NADP+), enzyme
# Mags Harries and Lajos Héder

Mags Harries and Lajos Héder are artists working collaboratively to create public art across the United States from their studio.

## Career

A married couple, they formed Harries/Héder Collaborative in 1990 and have worked together on major public art commissions since then. Based in Cambridge, Massachusetts, they have completed over thirty public projects with budgets up to $6 million. They designed Acoustic Weir in Cambridge, Massachusetts.

## Biographies

Mags Harries (born 1945), a Welsh sculptor born in Wales, attended Leicester College of Art before immigrating to the United States to study at Southern Illinois University. She teaches at the School of the Museum of Fine Arts, Boston on sculpture, installation, and public art. Her 1976 work Asaroton was installed in Boston. She created the Glove Cycle installation at a Boston subway station in 1984. Two of her untitled 1972 prints are held by Harvard Art Museums, and a 1975 charcoal on paper work Theater is held by Museum of Fine Arts, Boston.
Lajos Héder, an artist born in Hungary, studied architecture and urban planning at Harvard University. Before forming Harries/Héder Collaborative, he worked on community projects, urban design, site planning, architecture, and construction. He was the principal author of the US Department of Transportation's Aesthetics in Transportation (1980).
They have two daughters, writer/director Sian Heder and author/artist Thyra Heder.

## Selected works

* Wall Cycle to Ocotillo (1992), Phoenix, Arizona
* Miramar Park, Florida (2000)
* City at the Falls, Commonwealth Convention Center, Louisville, Kentucky (2000) design team artists
* Drawn Water, Cambridge Water Department, Cambridge, Massachusetts (2001) design team artist
* WaterWorks at Arizona Falls, Arizona Falls, Phoenix, Arizona (2003) design team artists
* The Benefit of Mr. Kite, San Diego Port Authority, San Diego, California (2003)
* Connections, [Central Connecticut State University], New Britain, Connecticut (2005)
* Arbors and Ghost Trees, Baseline Road, Phoenix, Arizona (2005) with Ten Eyck Landscape Architects
* Terra Fugit, Miramar Park, Fort Lauderdale, Florida (2006) design team artists
* The Big Question, Des Moines Science Museum, Des Moines, Iowa (2007)
* Concord River Greenway Trail Master Plan, Lowell, Massachusetts (2007)
* A MoonTide Garden, International Ferry Terminal, Portland, Maine (2007)
* Solar Light Raft, Havana Square, Stapleton, Colorado (2008)
* Sun Flowers, an Electric Garden, Mueller Development, Austin, Texas (2009)
* History Colorado Center, Denver, Colorado (2009)
* Zanjero's Line, Highline Canal, Phoenix, Arizona (2010) with Ten Eyck Landscape Architects
* Terpsichore for Kansas City, Arts District Parking Garage, Kansas City, Missouri (2011) with David Moulton, Roberta Vacca, Bobby Watson
* Xixi Umbrellas, Xixi Wetland Park, Hangzhou, China (2012) Westlake International Invitational Sculpture Exhibition
* Meeting Place, The Downtown Greenway, Greensboro, North Carolina (2014)
# CPAConnect

CPAConnect is an affiliate association of CPAmerica made up of small, independent Certified Public Accountant firms and sole practitioners in the United States, Puerto Rico and Mexico. CPAConnect is an alliance of CPAmerica, Inc., one of the nation’s largest associations of major independent CPA firms. Both associations operate out of CPAmerica’s headquarters building in Gainesville, Florida.
Total revenue of all CPAConnect firms is approximately $155 million. Average firm size is seven employees, which includes two partners. The total number of employees nationwide surpasses 1,650.
CPAConnect members receive practice management advice, CPE training, marketing products and access to national consultants. They share knowledge and information through e-mail discussion lists, conference calls, an online sharing library, an annual CPAConnect conference and other conferences with CPAmerica members.

## History

Founded in 1994, CPAConnect was created by its parent association, CPAmerica. Within a year, membership had grown to 60 firms. By 2004, membership had expanded to include more than 150 firms and, by 2015, nearly 200 firms.
# Mahecha

Mahecha is a Basque surname. Notable people with the surname include:
* Carlos Mahecha (born 1992), Colombian swimmer
* Juan Mahecha (born 1987), Colombian footballer
* Lizeth Mahecha (born 1971), Colombian actress
# Mahee Castle

Mahee Castle, also known as Nendrum Castle, is a small ruined tower house near Nendrum Monastery on Mahee Island in Strangford Lough, County Down, Northern Ireland. It was built in 1570 by Captain Thomas Browne. It was abandoned by the early 17th century, and fell into disrepair. In 1923, H.C. Lawlor and the Belfast Natural History and Philosophical Society partly renovated the tower house to avoid further erosion and built a buttress wall to support the northwest corner of the tower.

## Location

Mahee Castle is in the west of Mahee Island. It is beside a causeway; the only land crossing to the island. Today this causeway is crossed by a narrow road. Mahee Island is near the western shore of Strangford Lough, southeast of the town of Comber. The tower house sits on a drumlin. Nearby is a car park.

## Architecture

The rectangular tower house guards the bridge onto the island, and to the southwest there are the remains of a walled enclosure, known as a bawn. Mahee Castle encloses a boatbay, lying on the shore of the lake, and is quite small, with only two rooms on the ground floor. The main part, the tower-house, is three stories tall, although little remains of the upper floors. The entrance passes under a murder-hole.

## History

The tower house was built in 1570 by an English soldier, Captain Thomas Browne, after petition to the Bishop of Down. It was abandoned by the early 17th century. The corner stones may have been taken for local building projects, and stones from the northeastern wall were used to make the causeway to the island. During the 15th and 16th centuries, Mahee Castle was near the border of two territories: Clandeboye to the north and Dufferin to the south. At this time the area would have been subject to border conflicts, and Mahee Castle may have changed hands many times.
In 1923, under the direction of H.C. Lawlor, restoration works were undertaken by the Belfast Natural History and Philosophical Society. As part of this work, ivy was removed from the wall, cracks were grouted with cement, the top was waterproofed and a buttress wall was built to support the northeast corner of the tower.

### Excavations

Under a program sponsored by the Environment and Heritage Service of Ireland, archaeological excavations were carried out at Mahee Castle during 2001 and 2002. This included detailed stratigraphic sequencing, which revealed animal remains and remnants dated to the Late Medieval period, meaning that the building could have existed before 1570. The goal of the excavations was to evolve a restoration program.
The archaeological finds consisted of shells and animal bones, knives and an array of pottery ranging over several centuries. Large quantities of modern glass were found, in addition to flint and pot shards. The excavations revealed that the foundation of the tower was on an artificial terrace which was created for the purpose on the northeastern end of a drumlin. The rear end of this terrace had been stabilised by a buttress retaining wall built in 1923, 4 metres (13 ft) from the tower's southwestern end.
# COPS7A

COP9 signalosome complex subunit 7a is a protein that in humans is encoded by the COPS7A gene.