# 2018 Samarkand Challenger – Singles

Adrián Menéndez Maceiras was the defending champion but chose not to defend his title.
Luca Vanni won the title after defeating Mario Vilella Martínez 6–4, 6–4 in the final.

## Seeds

* Denis Istomin (first round)
* Attila Balázs (quarterfinals)
* Nikola Milojević (semifinals)
* Uladzimir Ignatik (semifinals)
* Lloyd Harris (quarterfinals)
* Aleksandr Nedovyesov (first round)
* Egor Gerasimov (first round)
* Yang Tsung-hua (quarterfinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| | Luca Vanni | 6 | 6 | | | |
| 4 | Uladzimir Ignatik | 3 | 3 | | | |
| 4 | Uladzimir Ignatik | 3 | 3 | Luca Vanni | 6 | 6 |
| | | | | Mario Vilella Martínez | 4 | 4 |
| 3 | Nikola Milojević | 2 | 4 | Mario Vilella Martínez | 4 | 4 |
| | Mario Vilella Martínez | 6 | 6 | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1/WC | D Istomin | 6$^3$ | 4 | | | | | | | | | | | | | | |
| | P Cachin | 7$^7$ | 6 | | | P Cachin | 6 | 4 | 6$^4$ | | | | | | | | |
| | L Vanni | 6 | 6 | | | L Vanni | 4 | 6 | 7$^7$ | | | | | | | | |
| | Carlos Boluda-Purkiss | 0 | 1 | | | | | | | | L Vanni | 6 | 6 | | | | |
| | A Šetkić | 7$^7$ | 6$^1$ | 6 | | | | | | 8 | T-h Yang | 2 | 4 | | | | |
| WC | S Fayziev | 6$^4$ | 7$^7$ | 3 | | A Šetkić | 2 | 3 | | | | | | | | | |
| WC | F Dustov | 1 | 3 | | 8 | T-h Yang | 6 | 6 | | | | | | | | | |
| 8 | T-h Yang | 6 | 6 | | | | | | | | | | | | L Vanni | 6 | 6 |
| 4 | U Ignatik | 6 | 6 | | | | | | | | | | | 4 | U Ignatik | 3 | 3 |
| | R Ortega Olmedo | 2 | 4 | | 4 | U Ignatik | 6 | 6$^5$ | 6 | | | | | | | | |
| Q | M Peña López | 6 | 6 | | Q | M Peña López | 4 | 7$^7$ | 1 | | | | | | | | |
| SE | S Betov | 1 | 1 | | | | | | | 4 | U Ignatik | 6 | 6 | | | | |
| | D Muñoz de la Nava | 6 | 6 | | | | | | | 5 | L Harris | 3 | 3 | | | | |
| | A Basso | 2 | 1 | | | D Muñoz de la Nava | 7$^7$ | 5 | 6$^3$ | | | | | | | | |
| WC | J Karimov | 3 | 3 | | 5 | L Harris | 6$^4$ | 7 | 7$^7$ | | | | | | | | |
| 5 | L Harris | 6 | 6 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | A Nedovyesov | 4 | 4 | | | | | | | | | | | | | | | |
| | M Zekić | 6 | 6 | | | M Zekić | 6 | 6 | | | | | | | | | | |
| Q | R Safiullin | 7$^7$ | 6 | | Q | R Safiullin | 1 | 4 | | | | | | | | | | |
| | T Gabashvili | 6$^4$ | 4 | | | | | | | | M Zekić | 2 | 1 | | | | | |
| | I Gakhov | 7 | 7$^7$ | | | | | | | 3 | N Milojević | 6 | 6 | | | | | |
| | Patricio Heras | 5 | 6$^5$ | | | I Gakhov | 3 | 4 | | | | | | | | | | |
| Q | S Fomin | 0 | 0 | | 3 | N Milojević | 6 | 6 | | | | | | | | | | |
| 3 | N Milojević | 6 | 6 | | | | | | | | | | | | 3 | N Milojević | 2 | 4 |
| 7 | E Gerasimov | 7 | 6$^8$ | 4 | | | | | | | | | | | | M Vilella Martínez | 6 | 6 |
| | M Vilella Martínez | 5 | 7$^{10}$ | 6 | | M Vilella Martínez | 6 | 5 | 6 | | | | | | | | | |
| | JC Aragone | 7$^9$ | 7$^7$ | | | JC Aragone | 4 | 7 | 0 | | | | | | | | | |
| | E Karlovskiy | 6$^7$ | 6$^5$ | | | | | | | | M Vilella Martínez | 5 | 6 | 6 | | | | |
| | F Horanský | 6 | 4 | 4 | | | | | | 2 | A Balázs | 7 | 4 | 4 | | | | |
| Q | S Balaji | 0 | 6 | 6 | Q | S Balaji | 6$^5$ | 6$^3$ | | | | | | | | | | |
| | C Rodríguez | 4 | 2 | | 2 | A Balázs | 7$^7$ | 7$^7$ | | | | | | | | | | |
| 2 | A Balázs | 6 | 6 | | | | | | | | | | | | | | | |