# List of estrogens

This is a list of steroidal estrogens or derivatives of estradiol, estrone, and estriol. Most esters of these estrogens are not included in this list; for esters, see here instead.

## Estradiol derivatives

| Compound | Chemical name | Marketed |
| Estradiol (E2) | Estra-1,3,5(10)-triene-3,17β-diol | ✓ |
| 2-Hydroxyestradiol | 2-Hydroxyestradiol | – |
| 4-Hydroxyestradiol | 4-Hydroxyestradiol | – |
| 4-Methoxyestradiol | 4-Methoxyestradiol | – |
| 8β-VE$_2$ | 8β-Vinylestradiol | – |
| 16α-IE$_2$ | 16α-Iodoestradiol | – |
| 16α-LE$_2$ | Estradiol 21,16α-lactone$^?$ | – |
| Cloxestradiol | Estradiol 17β-chloral hemiacetal ether | – |
| Cloxestradiol acetate | Estradiol 17β-chloral hemiacetal ether O,O-diacetate | ✓ |
| Estradiol sulfate | Estradiol 3-sulfate | – |
| Estrapronicate | Estradiol 3-propionate 17β-nicotinate | ✓ |
| Orestrate | Estradiol 3-propionate 17β-(1-cyclohexenyl) ether | – |
| Polyestradiol phosphate | Estradiol 17β-phosphate polymer | ✓ |
| Promestriene | Estradiol 3-propyl 17β-methyl diether | ✓ |

### 17α-Substituted estradiol derivatives

| Compound | Chemical name | Marketed |
| Cyclodiol | 14α,17α-Ethanoestradiol | – |
| Estrazinol | 8-Aza-17α-ethynylestradiol 3-methyl ether | – |
| Estrofurate | 17α-(3-Furyl)-δ$^7$-estradiol 3-acetate | – |
| Etamestrol (eptamestrol) | 1-Hydroxy-7α-methyl-17α-ethynylestradiol 1,3-dibenzoate | – |
| Ethinylestradiol (EE) | 17α-Ethynylestradiol | ✓ |
| Ethinylestradiol sulfonate (EES) | 17α-Ethynylestradiol 3-isopropylsulfonate | ✓ |
| Ethylestradiol | 17α-Ethylestradiol | – |
| Mestranol (EE3ME) | 17α-Ethynylestradiol 3-methyl ether | ✓ |
| Methylestradiol | 17α-Methylestradiol | ✓ |
| Moxestrol | 11β-Methoxy-17α-ethynylestradiol | ✓ |
| Quinestrol | 17α-Ethynylestradiol 3-cyclopentyl ether | ✓ |
| RU-16117 | 11α-Methoxy-17α-ethynylestradiol | – |

### Nitrogen mustard-coupled alkylating antineoplastic estradiol derivatives

| Compound | Chemical name | Marketed |
| Alestramustine | Estradiol 3-(bis(2-chloroethyl)carbamate) 17β-(2β-aminopropanoate) | – |
| Atrimustine | Estradiol 3-benzoate 17β-(4-(4-(bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)acetate | – |
| Estramustine | Estradiol 3-(bis(2-chloroethyl)carbamate) | – |
| Estramustine phosphate | Estradiol 3-(bis(2-chloroethyl)carbamate) 17β-phosphate | ✓ |

### 17β-Aminoestrogens

| Compound | Chemical name | Marketed |
| Aminoestradiol | 17β-Aminoestradiol | – |
| Butolame | 17β-((4-Hydroxybutyl)amino)estradiol | – |
| Hexolame | 17β-((6-Hydroxyhexyl)amino)estradiol | – |
| Pentolame | 17β-((5-Hydroxypentyl)amino)estradiol | – |
| Prodiame | 17β-((3-Aminopropyl)amino)estradiol | – |
| Prolame | 17β-((3-Hydroxypropyl)amino)estradiol | – |

## Estrone derivatives

| Compound | Chemical name | Marketed |
| Estrone (E1) | Estra-1,3,5(10)-triene-3-ol-17-one | ✓ |
| 2-Hydroxyestrone | 2-Hydroxyestrone | – |
| 4-Hydroxyestrone | 4-Hydroxyestrone | – |
| 4-Methoxyestrone | 4-Methoxyestrone | – |
| 16α-Hydroxyestrone | 16α-Hydroxyestrone | – |
| Almestrone | 7α-Methylestrone | ✓ |
| Clomestrone | 16α-Chloroestrone 3-methyl ether | ✓ |
| Estrone sulfate | Estrone 3-sulfate | ✓ |
| Estropipate | Estrone 3-sulfate piperazine salt | ✓ |
| Hydroxyestrone diacetate | 16α-Hydroxyestrone 3,16α-diacetate | ✓ |

### Nitrogen mustard-coupled alkylating antineoplastic estrone derivatives

| Compound | Chemical name | Structure | Marketed |
| Estromustine | Estrone 3-(bis(2-chloroethyl)carbamate) | | – |

## Estriol derivatives

| Compound | Chemical name | Marketed |
| Estriol (E3) | 16α-Hydroxyestradiol | ✓ |
| Estetrol (E4) | 15α-Hydroxyestriol | – |
| Quinestradol | Estriol 3-cyclopentyl ether | ✓ |

### 17α-Substituted estriol derivatives

| Compound | Chemical name | Marketed |
| Cyclotriol | 14α,17α-Ethanoestriol | – |
| Ethinylestriol | 17α-Ethynylestriol | – |
| Nilestriol | 17α-Ethynylestriol 3-cyclopentyl ether | ✓ |

## Other estrogen derivatives
### Epimers

| Compound | Chemical name | Marketed |
| 17α-Estradiol (alfatradiol) | 17α-Estradiol | ✓ |
| 16β-Epiestriol (epiestriol) | 16β-Hydroxy-17β-estradiol | ✓ |
| 17α-Epiestriol | 16α-Hydroxy-17α-estradiol | – |
| 16β,17α-Epiestriol | 16β-Hydroxy-17α-estradiol | – |
| Epimestrol | 17α-Epiestriol 3-methyl ether | ✓ |
| Mytatrienediol | 16α-Methyl-16β-epiestriol 3-methyl ether | – |

### Equine estrogens

| Compound | Chemical name | Marketed |
| Equilin | Δ$^7$-Estrone | ✓ |
| Equilenin | Δ$^{6,8}$-Estrone | ✓ |
| 17α-Dihydroequilin | Δ$^7$-17α-Estradiol | ✓ |
| 17β-Dihydroequilin | Δ$^7$-17β-Estradiol | ✓ |
| 17α-Dihydroequilenin | Δ$^{6,8}$-17α-Estradiol | ✓ |
| 17β-Dihydroequilenin | Δ$^{6,8}$-17β-Estradiol | ✓ |
| 8,9-Dehydroestrone | Δ$^8$-Estrone | ✓ |
| 8,9-Dehydroestradiol | Δ$^8$-17β-Estradiol | ✓ |
| Hippulin | Δ$^8$-14-Isoestrone | ✓ |