# Syndromes affecting the heart

A syndrome is a set of medical signs and symptoms that are correlated with each other. A syndrome can affect one or more of body systems. Different syndromes affect different groups of organs. This is a list of syndromes that may affect the heart. Syndromes affecting primarily the heart are written in bold letters.
| Syndrome | Cause | cardiac signs and symptoms | Other symptoms or organs affected | Notes |
| 1q21.1 deletion syndrome | genetic (Chromosome 1) | Cardiovascular anomalies are present in 30% of the cases (for example anomalous origin of the coronary artery in "Class II-deletion") | TAR syndrome Neuropsychiatric Craniofacial abnormalities Eye Kidney | |
| DiGeorge syndrome | genetic (Chromosome 22) | commonly interrupted aortic arch, truncus arteriosus and tetralogy of Fallot | Craniofacial Thymic aplasia Cleft palate Hypocalcemia/hypoparathyroidism | |
| Acute coronary syndrome | | Commonly associated with three clinical manifestations: ST elevation myocardial infarction (STEMI, 30%), non ST elevation myocardial infarction (NSTEMI, 25%), or unstable angina (38%) | | Blockage of a coronary artery |
| Adams–Nance syndrome | maybe disturbance in glycine metabolism | persistent tachycardia, paroxymal hypertension | Seizure Eye (Microphthalmia, Cataract) | |
| Alagille syndrome | genetic (Autosomal dominant inheritance: loss of function mutations in either JAG1 or NOTCH2) | Congenital heart problems e.g. pulmonary artery stenosis (common), Tetralogy of Fallot, overriding aorta, ventricular septal defect; and right ventricular hypertrophy. | Liver (jaundice, pruritus, hepatosplenomegaly, acholia, xanthoma) | |
| Andersen–Tawil syndrome | | | | This condition affects the QT interval (in blue) |
| Antley–Bixler syndrome | | | | |
| Barth syndrome | | | | |
| Brugada syndrome | | | | |
| Cantú syndrome | genetic (Chromosome 12, autosomal dominant) | | | |
| Cardiac syndrome X | | | | |
| Cardiorenal syndrome | | | Kidney | |
| Cat eye syndrome | | | | |
| CHARGE syndrome | | | | |
| Coffin–Lowry syndrome | genetic (RPS6KA3 gene mutation, Chromosome X) | | | |
| Costello syndrome | | | | |
| Down syndrome | genetic (Chromosome 21) | | | |
| Dressler syndrome | autoimmune inflammatory reaction secondary to MI. | | | |
| Edwards syndrome | genetic (Chromosome 18) | | | |
| Eisenmenger's syndrome | | | | |
| Ellis–van Creveld syndrome | | | | |
| Emanuel syndrome | | | | |
| HEC syndrome | | | | |
| Heyde's syndrome | | | | |
| Ho–Kaufman–Mcalister syndrome | | | | |
| Holt–Oram syndrome | | ASD, and a first degree heart block. | | |
| Hypoplastic left heart syndrome | | | | |
| Jacobsen syndrome | genetic (Chromosome 11q deletion) | | | |
| Jaffe–Campanacci syndrome | | | | |
| Jervell and Lange-Nielsen syndrome | genetic (autosomal recessive) | | | a type of long QT syndrome |
| Kabuki syndrome | | | | |
| Kearns–Sayre syndrome | | | | |
| Long QT syndrome | | | | |
| Lutembacher's syndrome | | | | |
| Malpuech facial clefting syndrome | | | | |
| Marden–Walker syndrome | | | | |
| Marfan syndrome | | | | |
| McKusick–Kaufman syndrome | | | | |
| McLeod syndrome | | | | |
| Noonan syndrome | | | | |
| Noonan syndrome with multiple lentigines | | | | |
| Ortner's syndrome | | | | |
| Bouveret Hoffmann syndrome | | | | another name for "Paroxysmal tachycardia" |
| Patau syndrome | genetic (Chromosome 13) | | | |
| Pre-excitation syndrome | | | | |
| Romano–Ward syndrome | | | | |
| Scimitar syndrome | | | | |
| Shone's syndrome | | | | |
| Short QT syndrome | | | | |
| Sick sinus syndrome | | | | |
| Taussig–Bing syndrome | | double outlet right ventricle (DORV) and subpulmonic VSD. | | a cyanotic congenital heart defect |
| Timothy syndrome | | | | |
| Townes–Brocks syndrome | | | | |
| Triploid syndrome | | | | |
| Turner syndrome | | | | |
| VACTERL syndrome | | | | |
| Wellens' syndrome | | | | |
| Williams syndrome | | | | |
| Wolff–Parkinson–White syndrome | | | | A Delta wave often seen in an affected individual |
| Zunich–Kaye syndrome | | | | |
| Lown–Ganong–Levine syndrome | | | | |