# 2022 San Luis Open Challenger – Singles

Marc-Andrea Hüsler was the defending champion but lost in the semifinals to Antoine Bellier.
Bellier won the title after defeating Renzo Olivo 6–7$^{(2–7)}$, 6–4, 7–5 in the final.

## Seeds

* Andrej Martin (quarterfinals)
* Nicolás Jarry (semifinals)
* Ernesto Escobedo (quarterfinals)
* Facundo Mena (first round)
* Jay Clarke (second round)
* Marc-Andrea Hüsler (semifinals)
* Federico Gaio (second round)
* Renzo Olivo (final)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| Q | Antoine Bellier | 2 | 6 | 6 | | | | | |
| 6 | Marc-Andrea Hüsler | 6 | 3 | 3 | | | | | |
| 6 | Marc-Andrea Hüsler | 6 | 3 | 3 | Q | Antoine Bellier | 6$^2$ | 6 | 7 |
| | | | | | 8 | Renzo Olivo | 7$^7$ | 4 | 5 |
| 8 | Renzo Olivo | 6 | 6 | | 8 | Renzo Olivo | 7$^7$ | 4 | 5 |
| 2 | Nicolás Jarry | 3 | 2 | | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | A Martin | 6 | 6 | | | | | | | | | | | | | | | | |
| | J Lenz | 1 | 1 | | 1 | A Martin | 2 | 6 | 6 | | | | | | | | | | |
| | N Kuhn | 7$^7$ | 5 | 6 | | N Kuhn | 6 | 4 | 4 | | | | | | | | | | |
| | JP Ficovich | 6$^2$ | 7 | 3 | | | | | | 1 | A Martin | 3 | 4 | | | | | | |
| | FC Jianu | 3 | 6 | 5 | | | | | | Q | A Bellier | 6 | 6 | | | | | | |
| Q | A Bellier | 6 | 3 | 7 | Q | A Bellier | 6 | 1 | 6 | | | | | | | | | | |
| Alt | P Krstin | 2 | 6 | 5 | 7 | F Gaio | 3 | 6 | 3 | | | | | | | | | | |
| 7 | F Gaio | 6 | 2 | 7 | | | | | | | | | | | Q | A Bellier | 2 | 6 | 6 |
| 4 | F Mena | 6$^3$ | 1 | | | | | | | | | | | | 6 | M-A Hüsler | 6 | 3 | 3 |
| | Zh Zhang | 7$^7$ | 6 | | | Zh Zhang | 7 | 6$^4$ | 6 | | | | | | | | | | |
| | N Mejía | 7 | 6$^3$ | 7$^7$ | | N Mejía | 5 | 7$^7$ | 3 | | | | | | | | | | |
| Alt | V Durasovic | 5 | 7$^7$ | 6$^3$ | | | | | | | Zh Zhang | 4 | 6 | 3 | | | | | |
| Q | J Shang | 4 | 7$^7$ | 6 | | | | | | 6 | M-A Hüsler | 6 | 3 | 6 | | | | | |
| Q | H Habib | 6 | 6$^1$ | 2 | Q | J Shang | 4 | 6$^6$ | | | | | | | | | | | |
| Q | R Quiroz | 6$^1$ | 3 | | 6 | M-A Hüsler | 6 | 7$^8$ | | | | | | | | | | | |
| 6 | M-A Hüsler | 7$^7$ | 6 | | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | R Olivo | 6 | 3 | 6 | | | | | | | | | | | | | | |
| | A Cazaux | 4 | 6 | 4 | 8 | R Olivo | 5 | 6 | 6 | | | | | | | | | |
| | G Oliveira | 6 | 7 | | | G Oliveira | 7 | 3 | 2 | | | | | | | | | |
| WC | S Mochizuki | 4 | 5 | | | | | | | 8 | R Olivo | 6 | 2 | 6 | | | | |
| | M Pucinelli de Almeida | 7$^7$ | 1 | 3 | | | | | | 3 | E Escobedo | 4 | 6 | 4 | | | | |
| | D Istomin | 6$^3$ | 6 | 6 | | D Istomin | 4 | 6 | 3 | | | | | | | | | |
| WC | A Hernández | 4 | 2 | | 3 | E Escobedo | 6 | 4 | 6 | | | | | | | | | |
| 3 | E Escobedo | 6 | 6 | | | | | | | | | | | | 8 | R Olivo | 6 | 6 |
| 5 | J Clarke | 6 | 6 | | | | | | | | | | | | 2 | N Jarry | 3 | 2 |
| Q | Matías Zukas | 3 | 4 | | 5 | J Clarke | 4 | 0 | | | | | | | | | | |
| | F Meligeni Alves | 7$^7$ | 6 | | | F Meligeni Alves | 6 | 6 | | | | | | | | | | |
| | E Donskoy | 6$^2$ | 3 | | | | | | | | F Meligeni Alves | 6 | 4 | 5 | | | | |
| Q | Gilbert Klier Júnior | 7$^9$ | 6 | | | | | | | 2 | N Jarry | 4 | 6 | 7 | | | | |
| WC | R Pacheco Méndez | 6$^7$ | 4 | | Q | G Klier Júnior | 7$^8$ | 4 | 4 | | | | | | | | | |
| | G Melzer | 6 | 3 | 6$^4$ | 2 | N Jarry | 6$^6$ | 6 | 6 | | | | | | | | | |
| 2 | N Jarry | 2 | 6 | 7$^7$ | | | | | | | | | | | | | | |