# 2022 Open de Oeiras – Singles

Gastão Elias was the defending champion and successfully defended his title, defeating Nino Serdarušić 6–3, 6–4 in the final.

## Seeds

* Benoît Paire (withdrew)
* Gianluca Mager (first round, retired)
* Stefano Travaglia (second round)
* Thiago Monteiro (quarterfinals)
* Zdeněk Kolář (second round)
* Nuno Borges (semifinals)
* Vít Kopřiva (quarterfinals)
* Alessandro Giannessi (semifinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| | Nino Serdarušić | 6 | 6 | | | |
| 6 | Nuno Borges | 2 | 3 | | | |
| 6 | Nuno Borges | 2 | 3 | Nino Serdarušić | 3 | 4 |
| | | | | Gastão Elias | 6 | 6 |
| 8 | Alessandro Giannessi | 3 | 3 | Gastão Elias | 6 | 6 |
| | Gastão Elias | 6 | 6 | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| Q | E Kırkın | 1 | 3 | | | | | | | | | | | | | | | |
| | N Serdarušić | 6 | 6 | | | N Serdarušić | 7$^7$ | 6 | | | | | | | | | | |
| Q | Lucas Gerch | 3 | 4 | | | P Sousa | 6$^3$ | 2 | | | | | | | | | | |
| | P Sousa | 6 | 6 | | | | | | | | N Serdarušić | 6$^5$ | 6 | 7 | | | | |
| Q | N Rubin | 4 | 6 | 6 | | | | | | Q | N Rubin | 7$^7$ | 2 | 5 | | | | |
| SE | D Michalski | 6 | 3 | 1 | Q | N Rubin | 6 | 6 | | | | | | | | | | |
| | M Bourgue | 4 | 1 | | 5 | Z Kolář | 4 | 4 | | | | | | | | | | |
| 5 | Z Kolář | 6 | 6 | | | | | | | | | | | | | N Serdarušić | 6 | 6 |
| 4 | T Monteiro | 7$^7$ | 7$^8$ | | | | | | | | | | | | 6 | N Borges | 2 | 3 |
| | GM Moroni | 6$^5$ | 6$^6$ | | 4 | T Monteiro | 6$^5$ | 6 | 7$^7$ | | | | | | | | | |
| | T Skatov | 6 | 6 | | | T Skatov | 7$^7$ | 2 | 6$^4$ | | | | | | | | | |
| WC | T Cação | 2 | 1 | | | | | | | 4 | T Monteiro | 7$^8$ | 6$^2$ | 5 | | | | |
| LL | F Forti | 2 | 1 | | | | | | | 6 | N Borges | 6$^6$ | 7$^7$ | 7 | | | | |
| | D Kuzmanov | 6 | 6 | | | D Kuzmanov | 6$^5$ | 5 | | | | | | | | | | |
| WC | Pedro Araújo | 4 | 2 | | 6 | N Borges | 7$^7$ | 7 | | | | | | | | | | |
| 6 | N Borges | 6 | 6 | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | A Giannessi | 6 | 6 | | | | | | | | | | | | | | | |
| | N Kuhn | 3 | 4 | | 8 | A Giannessi | 6 | 6 | | | | | | | | | | |
| Alt | R Bonadio | 6 | 6$^3$ | 6 | Alt | R Bonadio | 2 | 1 | | | | | | | | | | |
| | L Giustino | 2 | 7$^7$ | 0 | | | | | | 8 | A Giannessi | 1 | 7 | 6 | | | | |
| WC | J Domingues | 4 | 2 | | | | | | | | G Zeppieri | 6 | 5 | 3 | | | | |
| | G Zeppieri | 6 | 6 | | | G Zeppieri | 7$^{10}$ | 6 | | | | | | | | | | |
| Q | Matthieu Perchicot | 1 | 1 | | 3 | S Travaglia | 6$^8$ | 4 | | | | | | | | | | |
| 3 | S Travaglia | 6 | 6 | | | | | | | | | | | | 8 | A Giannessi | 3 | 3 |
| 7 | V Kopřiva | 6 | 6 | | | | | | | | | | | | | G Elias | 6 | 6 |
| Alt | L Rosol | 4 | 0 | | 7 | V Kopřiva | 6 | 6 | | | | | | | | | | |
| | D Popko | 3 | 2 | | Q | L Darderi | 3 | 2 | | | | | | | | | | |
| Q | L Darderi | 6 | 6 | | | | | | | 7 | V Kopřiva | 3 | 2 | | | | | |
| | G Elias | 6 | 3 | 6 | | | | | | | G Elias | 6 | 6 | | | | | |
| Q | A Rybakov | 4 | 6 | 2 | | G Elias | 6 | 4 | 7$^8$ | | | | | | | | | |
| Alt | A Vavassori | 4 | 6 | 4 | Alt | A Vavassori | 4 | 6 | 6$^6$ | | | | | | | | | |
| 2 | G Mager | 6 | 4 | 0$^r$ | | | | | | | | | | | | | | |