# 2021 Potchefstroom Open II – Singles

This was the second of two editions of the tournament in the 2021 tennis season. Benjamin Bonzi was the defending champion but lost in the second round to Jenson Brooksby.
Brooksby won the title after defeating Teymuraz Gabashvili 2–6, 6–3, 6–0 in the final.

## Seeds

* Prajnesh Gunneswaran (first round)
* Benjamin Bonzi (second round)
* Marc-Andrea Hüsler (second round)
* Liam Broady (semifinals)
* Jay Clarke (first round)
* Brayden Schnur (first round)
* Cem İlkel (quarterfinals)
* Peter Polansky (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| | Teymuraz Gabashvili | 1 | 6 | 6 | | | | | |
| 4 | Liam Broady | 6 | 4 | 4 | | | | | |
| 4 | Liam Broady | 6 | 4 | 4 | | Teymuraz Gabashvili | 6 | 3 | 0 |
| | | | | | PR | Jenson Brooksby | 2 | 6 | 6 |
| Q | Lucas Miedler | 5 | 2 | | PR | Jenson Brooksby | 2 | 6 | 6 |
| PR | Jenson Brooksby | 7 | 6 | | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | P Gunneswaran | 3 | 6 | 5 | | | | | | | | | | | | | | | |
| | A Santillan | 6 | 3 | 7 | | A Santillan | 6 | 3 | 6 | | | | | | | | | | |
| | N Kuhn | 6 | 6 | | | N Kuhn | 4 | 6 | 4 | | | | | | | | | | |
| | E Benchetrit | 3 | 4 | | | | | | | | A Santillan | 6$^5$ | 6 | 3 | | | | | |
| | T Gabashvili | 2 | 6 | 6 | | | | | | | T Gabashvili | 7$^7$ | 4 | 6 | | | | | |
| WC | Alec Beckley | 6 | 1 | 1 | | T Gabashvili | 6 | 1 | 6 | | | | | | | | | | |
| | U Blanch | 7$^7$ | 6 | | | U Blanch | 4 | 6 | 3 | | | | | | | | | | |
| 8 | P Polansky | 6$^4$ | 3 | | | | | | | | | | | | | T Gabashvili | 1 | 6 | 6 |
| 4 | L Broady | 6 | 6 | | | | | | | | | | | | 4 | L Broady | 6 | 4 | 4 |
| | V Galović | 3 | 1 | | 4 | L Broady | 6 | 6 | | | | | | | | | | | |
| Alt | V Kopřiva | 1 | 1 | | | G Blancaneaux | 3 | 0 | | | | | | | | | | | |
| | G Blancaneaux | 6 | 6 | | | | | | | 4 | L Broady | 4 | 6 | 6 | | | | | |
| | A Menéndez Maceiras | 6 | 6 | | | | | | | | A Menéndez Maceiras | 6 | 3 | 1 | | | | | |
| | Z Kolář | 4 | 0 | | | A Menéndez Maceiras | 6 | 6 | | | | | | | | | | | |
| WC | Khololwam Montsi | 6 | 6 | | WC | K Montsi | 3 | 0 | | | | | | | | | | | |
| 6 | B Schnur | 4 | 1 | | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5 | J Clarke | 7 | 3 | 6$^2$ | | | | | | | | | | | | | | |
| | D Kuzmanov | 5 | 6 | 7$^7$ | | D Kuzmanov | 7 | 7$^7$ | | | | | | | | | | |
| | R Quiroz | 5 | 5 | | | T Lamasine | 5 | 6$^5$ | | | | | | | | | | |
| | T Lamasine | 7 | 7 | | | | | | | | D Kuzmanov | 7 | 2 | 2 | | | | |
| Q | L Miedler | 6 | 6 | | | | | | | Q | L Miedler | 5 | 6 | 6 | | | | |
| | P Krstin | 2 | 0 | | Q | L Miedler | 4 | 6 | 6 | | | | | | | | | |
| WC | Vaughn Hunter | 3 | 2 | | 3 | M-A Hüsler | 6 | 3 | 4 | | | | | | | | | |
| 3 | M-A Hüsler | 6 | 6 | | | | | | | | | | | | Q | L Miedler | 5 | 2 |
| 7 | C İlkel | 6 | 7$^7$ | | | | | | | | | | | | PR | J Brooksby | 7 | 6 |
| PR | J Cagnina | 1 | 6$^1$ | | 7 | C İlkel | 7$^7$ | 7 | | | | | | | | | | |
| | C-h Tseng | 6 | 3 | 6 | | C-h Tseng | 6$^3$ | 5 | | | | | | | | | | |
| Q | M Bašić | 4 | 6 | 3 | | | | | | 7 | C İlkel | 1 | 4 | | | | | |
| Q | R Peniston | 7$^9$ | 2 | 2 | | | | | | PR | J Brooksby | 6 | 6 | | | | | |
| PR | J Brooksby | 6$^7$ | 6 | 6 | PR | J Brooksby | 6 | 5 | 6 | | | | | | | | | |
| Q | J Draper | 1 | 2 | | 2 | B Bonzi | 3 | 7 | 3 | | | | | | | | | |
| 2 | B Bonzi | 6 | 6 | | | | | | | | | | | | | | | |