OpenLLM-France/wikimedia huggingface dataset:
# Fibroblast growth factor receptor 4

Fibroblast growth factor receptor 4 (FGFR-4) is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334 (cluster of differentiation 334).
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. In a meta-analisis study, the functional polymorphism Gly388Arg (rs351855) of FGFR4 was observed to be significantly associated with nodal involvement and overall survival in patients with different types of cancer.

## Interactions

Fibroblast growth factor receptor 4 has been shown to interact with FGF1.
# Enfield 8000

The Enfield 8000 is a two-seater battery-electric city car, introduced in 1973 and developed in the United Kingdom by Isle of Wight company Enfield Automotive, owned by Greek millionaire Giannis Goulandris. The car was designed by a group of Greek and British engineers headed by Constantine Adraktas (Chairman and Managing Technical Director of Enfield) with John Ackroyd as project designer, who later went on to the Thrust 2 project. The prototypes and initial production were built at the Somerton Works in Northwood, near Cowes.
Immediately after its introduction, production was moved to the Greek island of Syros. 120 cars were built in total, of which 65 were used by the Electricity Council and electricity boards in the south of England.
Powered by an 8 bhp (6 kW) electric motor and lead-acid batteries, the car has a top speed of around 48 mph (77 km/h) and a range of around 40 miles (64 km). In Autocar's test in 1975 they found it had a usable range of 25 miles (40 km). It could accelerate from 0 to 10 mph (16 km/h) in 1.6 seconds, 20 mph (32 km/h) in 4.7 seconds and 30 mph (48 km/h) in 15.7 seconds. Brakes are by drums front and back.
It has a ladder-type square section tube chassis frame with aluminium alloy body panels stretched over steel frames. It uses suspension parts from the Hillman Imp, doors were adapted from the Mini and a rear axle derived from Reliant three-wheelers.

## Neorion

The company had been incorporated into the Greek Neorion company, also owned by Goulandris, and production was transferred to Syros, the company having transformed into a new Greek company, Enfield-Neorion, headquartered in Piraeus. There have been many arguments regarding the reason why Mr. Goulandris decided to produce the car in Greece, including conspiracy theories. Thanos Lebesis, then General Manager of Enfield-Neorion, argues that Mr. Goulandris had thought that "the company was owned by Greeks, the car was designed by Greeks, so it should also be produced by Greeks". However, it could not be legally sold in Greece due to tax categorization issues connected with electric power, so production was exported to the United Kingdom. Enfield-Neorion developments included a "Jeep" version aiming at the rent-a-car market in the Greek islands, but none could be sold locally.

## "Flux Capacitor"

A highly customised Enfield 8000 named "Jonny's Flux Capacitor" was converted by Jonny Smith into a street-legal electric drag racer. which for a time claimed to be the world's fastest street legal electric vehicle.
# Erin Kelly

Erin Kelly may refer to:
* Erin Kelly (actress) (born 1981), American actress
* Erin Kelly (author) (born 1976), British journalist
* Erin Entrada Kelly, Filipino-American writer of children's literature
* Erin I. Kelly, American philosopher
# Dyschromatosis symmetrica hereditaria

Dyschromatosis symmetrica hereditaria (also known as "reticulate acropigmentation of Dohi", and "symmetrical dyschromatosis of the extremities") is a rare autosomally inherited dermatosis. It is characterized by progressively pigmented and depigmented macules, often mixed in a reticulate pattern, concentrated on the dorsal extremities.$^{:855}$ It was first reported in Japan, but has also been found to affect individuals from Europe, India and the Caribbean.

## Genetics

This disease is caused by mutation in the double stranded RNA specific adenosine deaminase (ADAR1) gene. This gene is located on the long arm of chromosome 1 (1q21).

## Diagnosis

Diagnosis is by visualisation and skin biopsy.
# Clifton F. Conrad

Clifton F. Conrad is Vilas Distinguished Achievement Professor and Professor of Higher Education at the University of Wisconsin–Madison.
Conrad was president of the Association for the Study of Higher Education in 1987–1988. He has consulted, taught, or both in South America, Europe, Asia, and the Middle East.
# Galle (lunar crater)

Galle is a small lunar impact crater on the Mare Frigoris, to the north-northeast of the prominent crater Aristoteles. The formation is nearly circular, with a sharp-edged rim and little appearance of erosion. There are slight outward bulges in the rim to the north and northeast, but otherwise the formation is relatively symmetrical.

## Satellite craters

By convention these features are identified on lunar maps by placing the letter on the side of the crater midpoint that is closest to Galle.
| Galle | Latitude | Longitude | Diameter |
| A | 53.9° N | 22.3° E | 6 km |
| B | 55.4° N | 17.4° E | 7 km |
| C | 57.8° N | 24.5° E | 11 km |
# Chhotaki Masaudhi Halt railway station

Chhotaki Masaudhi Halt railway station is a halt railway station on the Patna–Gaya line under Danapur railway division of the East Central Railway zone. The station is situated beside Masaurhi Road at Tineri in Patna district in the Indian state of Bihar.

## History

Gaya was connected to Patna in 1900 by East Indian Railway Company by Patna–Gaya line. The Gaya to Jahanabad was electrified in 2002–2003. Electrification of the Patna–Gaya line was completed in 2003.
# Melrose Apartments

Melrose Apartments may refer to:
* Melrose Apartments (St. Louis, Missouri), listed on the National Register of Historic Places (NRHP) in St. Louis, Missouri
* Melrose Apartments (Omaha, Nebraska), listed on the NRHP in Nebraska as The Melrose
# Paramimiculus

Paramimiculus pterolophioides is a species of beetle in the family Cerambycidae, and the only species in the genus Paramimiculus. It was described by Breuning in 1964.
# Ferrissia tenuis

Ferrissia tenuis is a species of a freshwater snail or limpet, an aquatic gastropod in the family Planorbidae.

## Distribution

This species is found in India.

## Ecology

The population trend of this species is unknown.
Ferrissia tenuis is considered as a suspected host of Schistosoma haematobium in India.
# Endenicher Bach

Endenicher Bach ("stream of Endenich") is a river of North Rhine-Westphalia, Germany.
The Endenicher Bach is called Katzenlochbach at its origin but goes through some name changes on its way to a confluence with the Hardtbach (commonly known as the Dransdorfer Bach), which later flows into the river Rhine. It first changes into Endenicher Bach and later into Lengsdorfer Bach. With a length of 11 kilometres (6.8 mi), it's the longest stream in Bonn.
# Espace 1100

The Espace 1100 (English: Space) is a French sailboat that was designed by Philippe Briand as a cruiser and first built in 1985. The boat is one of the Espace series of cruising sailboats and its designation indicates its approximate length overall in centimeters.

## Production

The design was built by Jeanneau in France, from 1985 until 1989.

## Design

The Espace 1100 is a recreational keelboat, built predominantly of fiberglass, with wood trim. It has a masthead sloop rig, with aluminum spars with stainless steel wire rigging. The hull has a raked stem, a reverse transom with a swimming platform, a skeg-mounted rudder controlled by two wheels, one in the cockpit and one in the wheelhouse. It has a fixed fin keel or optional keel and centerboard. The fin keel version displaces 14,080 lb (6,387 kg) and carries 4,873 lb (2,210 kg) of ballast, while the centerboard-equipped version displaces 14,168 lb (6,426 kg).
The keel-equipped version of the boat has a draft of 5.42 ft (1.65 m), while the centerboard-equipped version has a draft of 7.33 ft (2.23 m) with the centerboard extended and 4.0 ft (1.2 m) with it retracted, allowing operation in shallow water.
The boat is fitted with a British Perkins Engines 4-154 diesel engine for docking and maneuvering. The fuel tank holds 52 U.S. gallons (200 L; 43 imp gal) and the fresh water tank has a capacity of 66 U.S. gallons (250 L; 55 imp gal).
The design has sleeping accommodation for six people, with a double "V"-berth in the bow cabin, double settee port amidships and an aft cabin with a double berth on the starboard side. The galley is located on the starboard amidships. The galley is equipped with a two-burner stove, ice box and a double sink. A navigation station is opposite the galley, centered above, in the wheelhouse next to the salon. The head is located just aft of the bow cabin on the port side and includes a shower.
For sailing downwind the design may be equipped with a symmetrical spinnaker.
The design has a hull speed of 7.36 kn (13.63 km/h).
# Cairo Skywatch Tower

Cairo Skywatch Tower, also known as Delta Lima 3 Green Ground Observation Tower, is a historic watchtower located in Tippecanoe Township, Tippecanoe County, Indiana. It was built in 1952, and is a 40-foot tall wooden structure. It once had a glass-enclosed office. It was the first officially commissioned rural skywatch tower by the United States Air Force's Civilian Ground Observation Corps under the Operation Skywatch program.$^{:5–6}$ In 1959, after the dissolution of the Civilian Ground Observation Corps, the watchtower was also abandoned.
It was listed on the National Register of Historic Places in 2002.
# Laraesima ochreoapicalis

Laraesima ochreoapicalis is a species of beetle in the family Cerambycidae. It was described by Stephan von Breuning in 1973. It is known from Brazil.
# Paramimus

Paramimus is a genus of skippers in the family Hesperiidae.
# Festival IGA Supermarkets

Festival IGA Supermarkets (also known as Festival Supermarkets or Festival IGA) was a branding name for IGA. The name was launched in June 1992 in Victoria by Davids Holdings (now known as Metcash). The first Festival IGA supermarkets were launched in Canberra on 26 October 1992 in Hackett, Lyneham, Florey, Charnwood, Kingston and Hawker.
Within 1995, more Festival IGA Supermarkets were opened throughout Canberra and New South Wales: Deakin, Richardson, Kaleen, Jindabyne, Tumut, Merimbula, Moruya, Batemans Bay, Ainslie and Wanniassa.
By 1999, the Festival brand had disappeared and was renamed under the IGA banner. However, the IGA Supermarkets in Tasmania kept the Festival branding until at least 2012.

## Slogans

* "Best and Fresh and Costs you Less"
* "The Friendly sized supermarket"

## Logo

The logo for Festival IGA was the wording "Festival" in a red font with yellow shadowing in the background and there was a blue star on top of the "I".
# Espace 800

The Espace 800 (English: Space) is a French sailboat that was designed by Philippe Briand as a cruising motorsailer and first built in 1981. The boat is part of the Espace series of cruising sailboats and its designation indicates its length overall in centimeters.

## Production

The design was built by Jeanneau in France, from 1981 to 1984, but it is now out of production.

## Design

The Espace 800 is a recreational keelboat, built predominantly of fiberglass. It has a fractional sloop rig, with a single set of spreaders and aluminum spars with stainless steel wire rigging. The mainsheet is rigged to a cockpit arch. The hull has a raked stem, a reverse transom, an internally mounted spade-type rudder controlled by a wheel and a fixed stub keel with a retractable centerboard. It displaces 7,716 lb (3,500 kg) and carries 2,646 lb (1,200 kg) of ballast.
The boat has a draft of 6.07 ft (1.85 m) with the centerboard extended and 3.22 ft (0.98 m) with it retracted, allowing operation in shallow water or ground transportation on a trailer.
The boat is fitted with an inboard engine for docking and maneuvering. The fuel tank holds 29 U.S. gallons (110 L; 24 imp gal) and the fresh water tank has a capacity of 25 U.S. gallons (95 L; 21 imp gal).
The design has sleeping accommodation for five people, with a double "V"-berth in the bow cabin, an L-shaped settee and a straight settee in the main cabin. The galley is located on the port side amidships. The galley is equipped with a two-burner stove and a sink. The head is located just aft of the bow cabin on the starboard side and includes a shower.
The design has a hull speed of 6.07 kn (11.24 km/h).
# Buccinum fukureum

Buccininum fukureum is a species of Buccinidae. The species is distributed in the southern Sea of Okhotsk, off the Gulf of Patience. Specimens have generally measured 90-92 millimeters. The species is generally found at depths of about 250–300 meters. The species was first described in 1976.
# Galford

Galford can refer to:
* Ellen Galford, American-born Scottish writer
* Galford near Lew Trenchard in Devon, England; the likely site of Gafulford where a battle took place in 825 AD
* Galford D. Weller, a character from the Samurai Shodown game series
* Robert M. Galford, American author
# Paramillo Massif

The Paramillo Massif (Nudo de Paramillo) is a mountain range of the Tropical Andes System, located at the northern end of the Cordillera Occidental (West Andes) range in Colombia.

## Geography

Administratively, the Paramillo Massif is located in the municipalities of Ituango and Peque in Antioquia Department; and Puerto Libertador and Tierralta in Córdoba Department.
The municipalities that surround this massif are Chigorodó, Mutatá, Tarazá, Cáceres and Caucasia in Antioquia.
This massif is intervisible with several peaks in the Sierra Nevada, e.g. Pico Simón Bolívar 5,700 m (18,700 ft) in the north of Colombia. This implies a theoretical direct line of sight of just over 500 km (310 mi), reported to be the longest between any two points on the surface of the Earth.

### Subranges

This mountainous region gives rise to three smaller ranges that spread northward and recede into the Caribbean plain.
* The Abibe Mountains (Serranía de Abibe) form a natural border between the Antioquia Department and Córdoba Department.
* The San Jerónimo Mountains (Serranía de San Jerónimo) separates the watersheds of the San Jorge River and Sinú River.
* The Ayapel Mountains (Serranía de Ayapel) divides the watersheds of the San Jorge and Cauca Rivers, as well as forming a natural border between Antioquia and Córdoba Departments.

### Paramillo Natural National Park

Most of the area is within the Paramillo Natural National Park, which extends from the massif into the lowlands of the Caribbean Plain. The ecosystems found within the massif are characteristic of the Tropical Andes which include páramo and mountain forests.
It is one of two regions where the bird Paramillo tapaculo (Scytalopus canus), an endangered species, is found.
One of the massif's highland mammal species is the vulnerable Spectacled bear (Tremarctos ornatus).
# Bumetopia trigonocephala

Bumetopia trigonocephala is a species of beetle in the family Cerambycidae. It was described by Heller in 1923. It is known from the Philippines.
# Festival Iberoamericano de Publicidad

Festival Iberoamericano de Publicidad was created in 1969 by Alberto Gollán - a pioneer of Argentine Television. The objective of this first Spanish and Portuguese-speaking advertising festival, has been since then, to promote and integrate the communication of the region.
The globalization of the communications and the use of new techniques made the FIAP to widen its spectrum with the creation of new disciplines matching those changes:
Media Innovation, Audiovisual Production Techniques and Interactive and Direct Marketing are the most relevant.
More than 8500 advertisements compete in the Festival, and around 2000 delegates from Ibero-America, United States and Europe participate of the event every year.
The winners of FIAP are included into ABC Show
# Filopaludina sumatrensis

Filopaludina sumatrensis is a species of large freshwater snail with a gill and an operculum, an aquatic gastropod mollusc in the family Viviparidae.

## Subspecies

* Filopaludina sumatrensis peninsularis Brandt, 1974
* Filopaludina sumatrensis polygramma (Martens, 1860)
* Filopaludina sumatrensis speciosa (Deshayes, 1876)
* Filopaludina sumatrensis sumatrensis (Dunker, 1852) represented as Filopaludina sumatrensis (Dunker, 1852) (alternate representation)

## Distribution

This species is found in Cambodia, Indonesia, Laos, Malaysia, Myanmar, Singapore, Thailand and Vietnam.

## Description

The width of the shell is 21 mm. The height of the shell is 32 mm.
# Escanaba in Love

Escanaba in Love is the play written by Jeff Daniels as a prequel to Escanaba in da Moonlight (1995). It had its world premiere in 2006 at the Purple Rose Theatre with former PRTC Apprentices Charlyn Swarthout as Big Betty Baloo and Jake Christensen as Albert Soady, Jr.
# Calagrassor tashiensis

Calagrassor tashiensis is a species of sea snail, a marine gastropod mollusk in the family Eosiphonidae, the true whelks and their allies.

## Distribution

This marine species occurs off Taiwan.
# EPB41L1

Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene.

## Function

Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them has been determined.

## Interactions

EPB41L1 has been shown to interact with:
* CENTG1,
* Dopamine receptor D2,
* Dopamine receptor D3,
* ITPR1, and
* Nuclear mitotic apparatus protein 1.
# Buccinum coronatum

Buccinum coronatum is a species of sea snail, a marine gastropod mollusk in the family Buccinidae, the true whelks.

## Nomenclature

The species Buccinum coronatum Golikov, 1980, is valid, but the name is preoccupied several times. The name is thus invalid, but it has no synonym or replacement name. One is needed. .
* Buccinum coronatum Bruguière, 1789: synonym of Nassarius coronatus (Bruguière, 1789)
* Buccinum coronatum Gmelin, 1791: synonym of Nassa serta (Bruguière, 1789)
* Buccinum coronatum Quoy & Gaimard, 1833: synonym of Nassarius distortus (A. Adams, 1852)
# Lanzhou Xinqu railway station

Lanzhou Xinqu railway station (Chinese: 兰州新区站; pinyin: Lánzhōu Xīnqū zhàn; lit. 'Lanzhou New Area railway station') is a railway station located in Lanzhou New Area, Yongdeng County in Lanzhou, on the Lanzhou–Zhongchuan Airport Intercity Railway.
It takes about 30 minutes to the Lanzhou West railway station as well as the city proper, although the station is close to the commercial centre of the Qilihe District. The station is opened on 30 September 2015, along with the railway.
# More to Life

"More to Life" is a theme-song to the early 1990s Trainer TV series. The song was written by Simon May and Mike Read. The theme won them a TRIC award for Best TV Theme.
Sung by Cliff Richard, it was released as a single in the UK in September 1991 and reached number 23 on the UK Singles Chart.

## Track listing

UK 7" single (EM 205), CD single (CDEM 205), cassette (TCEM 205)
* "More to Life"
* "Mo's Theme" (instrumental)

## Chart performance

| Chart (1992) | Peak position |
| UK Singles (OCC) | 23 |
# Don't Wake Me

"Don't Wake Me" is a song by Australian pop-rock group Uncanny X-Men. The song was released in September 1986 as the second single from the band's second studio album, What You Give Is What You Get. The song peaked at number 31 on the Kent Music Report.

## Track listing

7" Vinyl (CBS - BA 3486)
* "Don't Wake Me"
* "Truckin' on into Alice"

## Charts

| Chart (1986) | Position |
| Australian Kent Music Report | 31 |
# Chientina

Chientina is a village in Tuscany, central Italy, administratively a frazione of the comune of Terricciola, province of Pisa.
Chientina is about 32 km from Pisa and 5 km from Terricciola.
# Autosomal recessive GTP cyclohydrolase I deficiency

Autosomal recessive GTP cyclohydrolase I deficiency (AR-GTPCHD) is a disorder associated with the deficient operation of the enzyme GTP cyclohydrolase I. The condition leads to insufficient production of the cofactor tetrahydrobiopterin necessary for the proper synthesis of dopamine and serotonin and for maintenance of adequate levels of phenylalanine. As of 2020, autosomal recessive GTP cyclohydrolase I deficiency was one of the six known causes of tetrahydrobiopterin deficiency. It is also considered part of the spectrum of dopa-responsive dystonias.

## Symptoms and signs

Patients may present with developmental delay, axial hypotonia, delayed development of speech, or dysarthria. The list of possible motor disturbances includes dystonia, oculogyric crises, parkinsonism/hypokinesia. Patients may have a number of psychiatric symptoms.
Biochemically, patients present with hyperphenylalaninemia, and usually have decreased levels of biopterin and neopterin in urine and in dry blood spots.

## Treatment

According to a consensus guideline published in 2020, patients may be put on a phenylalanine-restricted diet to help bring down their elevated phenylalanine levels. To the same effect, and to normalise their production of neurotransmitters, they may be prescribed sapropterin, an artificially produced analogue of tetrahydrobiopterin. Another first-line drug in this disease is L-DOPA. Prescription of 5-hydroxytryptophan is also possible.
Prolonged therapy with large doses of L-DOPA may lead to the development of cerebral folate deficiency, therefore patients with decreased concentrations of 5-MTHF in their cerebrospinal fluid may be prescribed folinic acid, which efficiently penetrates the blood-cerebrospinal fluid barrier and helps restore the folate status.
# Final Vinyl

Final Vinyl may refer to:
* Final Vinyl (Hot Tuna album), 1979
* Final Vinyl (The Teardrops album), 1980
# CloudBioLinux

CloudBioLinux is an open-source project providing machine images for bioinformatics on cloud computing platforms. CloudBioLinux provides a build and deployment system which can deploy directly to desktop machines, to desktop Virtual Machines (VMs), or to cloud providers such as the Amazon Elastic Compute Cloud (EC2). The project also provides a pre-built Amazon Machine Image (AMI) for use on Amazon EC2, and downloadable pre-built virtual machine images for the desktop virtual machine software VirtualBox and for use on a private Eucalyptus cloud.

## Related projects

BioLinux provides linux distributions configured for bioinformatics. The CloudBioLinux project grew out of the BioLinux project.
The open-source CloudMan project builds on CloudBioLinux and Galaxy to provide pre-configured Galaxy virtual clusters on cloud computing platforms.
# E231

E231 may refer to:
* 2-Phenylphenol, a food additive
* E231 series, a Japanese train type
* European route E231, a European Class-B road in the Netherlands