# 2018 Uruguay Open – Singles

Pablo Cuevas was the defending champion but lost in the first round to Mario Vilella Martínez.
Guido Pella won the title after defeating Carlos Berlocq 6–3, 3–6, 6–1 in the final.

## Seeds

* Pablo Cuevas (first round)
* Guido Pella (champion)
* Guido Andreozzi (second round)
* Pablo Andújar (second round)
* Thiago Monteiro (second round)
* Hugo Dellien (second round)
* Paolo Lorenzi (second round)
* Juan Ignacio Londero (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| | Mario Vilella Martínez | 1 | 4 | | | | | | |
| | Carlos Berlocq | 6 | 6 | | | | | | |
| | Carlos Berlocq | 6 | 6 | | | Carlos Berlocq | 3 | 6 | 1 |
| | | | | | 2 | Guido Pella | 6 | 3 | 6 |
| | Pedro Sousa | 6 | 3 | 4 | 2 | Guido Pella | 6 | 3 | 6 |
| 2 | Guido Pella | 2 | 6 | 6 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals |
| 1 | P Cuevas | 2 | 2 | | | | | | | | | | | | | | |
| | M Vilella Martínez | 6 | 6 | | | M Vilella Martínez | 6 | 7$^7$ | | | | | | | | | |
| WC | T Seyboth Wild | 2 | 6 | 2 | Q | D Kuzmanov | 2 | 6$^3$ | | | | | | | | | |
| Q | D Kuzmanov | 6 | 4 | 6 | | | | | | | M Vilella Martínez | 6 | 6 | | | | |
| WC | C Taberner | 6$^7$ | 6$^5$ | | | | | | | WC | M Cuevas | 3 | 4 | | | | |
| WC | M Cuevas | 7$^9$ | 7$^7$ | | WC | M Cuevas | 4 | 7 | 7 | | | | | | | | |
| Q | F Díaz Acosta | 2 | 5 | | 5 | T Monteiro | 6 | 5 | 5 | | | | | | | | |
| 5 | T Monteiro | 6 | 7 | | | | | | | | | | | | M Vilella Martínez | 1 | 4 |
| 4 | P Andújar | 6 | 6 | | | | | | | | | | | | C Berlocq | 6 | 6 |
| | J Domingues | 0 | 3 | | 4 | P Andújar | 6$^4$ | 5 | | | | | | | | | |
| Alt | F Argüello | 5 | 6 | 6 | Alt | F Argüello | 7$^7$ | 7 | | | | | | | | | |
| | A De Greef | 7 | 3 | 3 | | | | | | Alt | F Argüello | 3 | 6 | 5 | | | |
| | F Bagnis | 2 | 0 | | | | | | | | C Berlocq | 6 | 3 | 7 | | | |
| | C Berlocq | 6 | 6 | | | C Berlocq | 3 | 6 | 7 | | | | | | | | |
| Q | F Coria | 6 | 0 | 6$^2$ | 7 | P Lorenzi | 6 | 2 | 5 | | | | | | | | |
| 7 | P Lorenzi | 3 | 6 | 7$^7$ | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | H Dellien | 6 | 6 | | | | | | | | | | | | | | | | |
| WC | F Llanes | 2 | 3 | | 6 | H Dellien | 5 | 5 | | | | | | | | | | | |
| | D Gimeno Traver | 6 | 6 | | | D Gimeno Traver | 7 | 7 | | | | | | | | | | | |
| | G Elias | 4 | 1 | | | | | | | | D Gimeno Traver | 6 | 5 | 1 | | | | | |
| | G Clezar | 1 | 2 | | | | | | | | P Sousa | 3 | 7 | 6 | | | | | |
| | P Sousa | 6 | 6 | | | P Sousa | 6 | 6 | | | | | | | | | | | |
| Q | Juan Ignacio Galarza | 6 | 5 | 3 | 3 | G Andreozzi | 1 | 3 | | | | | | | | | | | |
| 3 | G Andreozzi | 1 | 7 | 6 | | | | | | | | | | | | P Sousa | 6 | 3 | 4 |
| 8 | JI Londero | 7 | 1 | 2 | | | | | | | | | | | 2 | G Pella | 2 | 6 | 6 |
| | P Cachin | 5 | 6 | 6 | | P Cachin | 1 | 3 | | | | | | | | | | | |
| | L Giustino | 6 | 6 | | | L Giustino | 6 | 6 | | | | | | | | | | | |
| | T Bellucci | 3 | 3 | | | | | | | | L Giustino | 1 | 2$^r$ | | | | | | |
| | F Gaio | 6$^5$ | 5 | | | | | | | 2 | G Pella | 6 | 3 | | | | | | |
| | P Krstin | 7$^7$ | 7 | | | P Krstin | 6 | 3 | 5 | | | | | | | | | | |
| | R Cid Subervi | 4 | 1 | | 2 | G Pella | 1 | 6 | 7 | | | | | | | | | | |
| 2 | G Pella | 6 | 6 | | | | | | | | | | | | | | | | |