# Andrea Hayes-Jordan

Andrea A. Hayes Dixon (born 1965) is an American surgeon. She was the first pediatric surgeon to perform a high-risk, life-saving procedure in children with a rare form of cancer and developed the first orthotropic xenograft model of metastatic Ewing's sarcoma. In 2002, she became the first African American female pediatric surgeon board-certified in the United States.
Dixon is the Chairwoman of Surgery at Howard University Hospital.

## Early life and education

Dixon was born in Los Angeles, California in 1965. She enrolled at Dartmouth College for a Bachelor of Arts degree in Religion but accepted an opportunity to work in a leukemia lab at the medical school. Dixon then enrolled at Geisel School of Medicine wanting to be a pediatrician but was inspired by Thomas Colacchio to shift her focus. While completing her sub-internship at Stanford University, she studied pediatric surgery and chose to pursue the profession as a career.

## Career

Upon graduating from medical school, Dixon decided to focus on pediatric surgery but was rejected three times from hospitals for their training programs. When her mentor asked why she was being rejected, one surgeon replied that bringing in the first black woman was too much of a risk for his program. As a result, Hayes-Jordan went to a training program in Toronto and in 2002, she became the first black, female, board-certified pediatric surgeon in the United States. She started working with children with cancer at St. Jude's Hospital before specifically focusing on abdomen cancer.
Six years later, Dixon developed the first orthotropic xenograft model of metastatic Ewing's sarcoma while simultaneously completing the first cytoreductive surgery and hyper-thermic intraperitoneal chemotherapy HIPEC for children with sarcomatosis. By 2006, Dixon became the first surgeon in the United States to successfully use hyperthermic intraperitoneal chemotherapy on a child. During the 12-hour operation, she removed all the tumors before pumping a chemotherapy drug heated to 103 degrees throughout the abdominal cavity.

### UNC

In 2018, Dixon was appointed Chief of the Division of Pediatric Surgery at UNC School of Medicine and named Surgeon-in-Chief at the North Carolina Children's Hospital. While serving in this role, she was appointed by President Donald Trump to sit on the National Cancer Advisory Board, where she would advise and assist the National Cancer Institute Director on the activities of the National Cancer Program. On September 25, 2019, Hayes-Jordan was honored with the Byah Thomason Doxey-Sanford Doxey Distinguished Professorship.
During the COVID-19 pandemic in North America, Dixon was named to American Pediatric Surgical Association's board of directors and elected President of the Society of Black Academic Surgeons, replacing Martin Karpeh. She was also recognized by the Triangle Business Journal as one of its 2020 Health Care Heroes for her "outstanding accomplishments as a surgeon, teacher, and leader."

## Personal life

Dixon was married to former National Football League linebacker Darin Jordan; the couple had two children.She is now married to Philadelphia author Hugh Nichols Dixon Sr.

## Selected papers

* Emma C Hamilton; Thomas Curtin; Rebecca S Slack; Christine Ge; Austen D Slade; Andrea Hayes-Jordan; Kevin P Lally; Mary T Austin (3 July 2017). "Surgical Feeding Tubes in Pediatric and Adolescent Cancer Patients: A Single-institution Retrospective Review". Journal of Pediatric Hematology/Oncology. doi:10.1097/MPH.0000000000000902. ISSN 1077-4114. PMC 5610072. PMID 28678086. Wikidata Q38662651.
* David O Walterhouse; Alberto S Pappo; Jane L Meza; et al. (17 February 2017). "Reduction of cyclophosphamide dose for patients with subset 2 low-risk rhabdomyosarcoma is associated with an increased risk of recurrence: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group". Cancer. 123 (12): 2368–2375. doi:10.1002/CNCR.30613. ISSN 0008-543X. PMC 5662934. PMID 28211936. Wikidata Q40330433.
* Carmen Lopez; Arlene Correa; Ara Vaporciyan; Mary Austin; David Rice; Andrea Hayes-Jordan (28 October 2016). "Outcomes of chest wall resections in pediatric sarcoma patients". Journal of Pediatric Surgery. 52 (1): 109–114. doi:10.1016/J.JPEDSURG.2016.10.035. ISSN 0022-3468. PMID 27914587. Wikidata Q39028317.
* Benjamin Freemyer; Emma Hamilton; Carla L Warneke; Ali M Ali; Cynthia Herzog; Andrea Hayes-Jordan; Mary Austin (17 September 2016). "Treatment outcomes in pediatric melanoma-Are there benefits to specialized care?". Journal of Pediatric Surgery. 51 (12): 2063–2067. doi:10.1016/J.JPEDSURG.2016.09.039. ISSN 0022-3468. PMID 27686483. Wikidata Q40560126.
* Andrea Hayes-Jordan; Michael P LaQuaglia; Shakeel Modak (14 September 2016). "Management of desmoplastic small round cell tumor". Seminars in pediatric surgery. 25 (5): 299–304. doi:10.1053/J.SEMPEDSURG.2016.09.005. ISSN 1055-8586. PMC 5614508. PMID 27955733. Wikidata Q39036554.
* Pascal Owusu-Agyemang; Juan P Cata; Keith F Fournier; Acsa M Zavala; Jose Soliz; Mike Hernandez; Andrea Hayes-Jordan; Vijaya Gottumukkala (14 March 2016). "Evaluating the Impact of Total Intravenous Anesthesia on the Clinical Outcomes and Perioperative NLR and PLR Profiles of Patients Undergoing Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy". Annals of Surgical Oncology. 23 (8): 2419–2429. doi:10.1245/S10434-016-5176-5. ISSN 1068-9265. PMID 26975738. Wikidata Q38774380.
* Andrea Hayes-Jordan; C Lopez; H L Green; L C Xiao; W Huh; C E Herzog (25 October 2015). "Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in pediatric ovarian tumors: a novel treatment approach". Pediatric Surgery International. 32 (1): 71–73. doi:10.1007/S00383-015-3814-9. ISSN 0179-0358. PMC 5098267. PMID 26500075. Wikidata Q37397505.
* Andrea Hayes-Jordan (1 August 2015). "Cytoreductive Surgery Followed by Hyperthermic Intraperitoneal Chemotherapy in DSRCT: Progress and Pitfalls". Current Oncology Reports. 17 (8): 38. doi:10.1007/S11912-015-0461-1. ISSN 1523-3790. PMID 26092407. Wikidata Q38532596.
* Allyson M Womack; Andrea Hayes-Jordan; Rajarshi Pratihar; Denise A Barringer; James H Hall; Paul W Gidley; Jan S Lewin (1 November 2014). "Evaluation of ototoxicity in patients treated with hyperthermic intraperitoneal chemotherapy (HIPEC) with cisplatin and sodium thiosulfate". Ear and Hearing. 35 (6): e243-7. doi:10.1097/AUD.0000000000000070. ISSN 0196-0202. PMC 4208970. PMID 25127324. Wikidata Q34401647.
* Andrea Hayes-Jordan; Yong Xin Wang; Peter Walker; Charles S Cox (30 May 2014). "Mesenchymal Stromal Cell Dependent Regression of Pulmonary Metastasis from Ewing's". Frontiers in pediatrics. 2: 44. doi:10.3389/FPED.2014.00044. ISSN 2296-2360. PMC 4039072. PMID 24910847. Wikidata Q33688230.
* Pascal Owusu-Agyemang; Jose Soliz; Andrea Hayes-Jordan; Nusrat Harun; Vijaya Gottumukkala (28 August 2013). "Safety of epidural analgesia in the perioperative care of patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy". Annals of Surgical Oncology. 21 (5): 1487–1493. doi:10.1245/S10434-013-3221-1. ISSN 1068-9265. PMID 23982249. Wikidata Q33410026.
* Vivek Subbiah; Robert E Brown; Yunyun Jiang; Jamie Buryanek; Andrea Hayes-Jordan; Razelle Kurzrock; Pete M Anderson (29 July 2013). "Morphoproteomic profiling of the mammalian target of rapamycin (mTOR) signaling pathway in desmoplastic small round cell tumor (EWS/WT1), Ewing's sarcoma (EWS/FLI1) and Wilms' tumor(WT1)". PLOS One. 8 (7): e68985. Bibcode:2013PLoSO...868985S. doi:10.1371/JOURNAL.PONE.0068985. ISSN 1932-6203. PMC 3726753. PMID 23922674. Wikidata Q34901968.
* Winston W Huh; Nancy E Fitzgerald; Anita Mahajan; Andrea Hayes-Jordan (21 September 2012). "Peritoneal sarcomatosis in pediatric malignancies". Pediatric Blood & Cancer. 60 (1): 12–17. doi:10.1002/PBC.24293. ISSN 1545-5009. PMID 23002005. Wikidata Q38045850.
* Beverly Raney; Winston Huh; Douglas Hawkins; et al. (7 September 2012). "Outcome of patients with localized orbital sarcoma who relapsed following treatment on Intergroup Rhabdomyosarcoma Study Group (IRSG) Protocols-III and -IV, 1984-1997: a report from the Children's Oncology Group". Pediatric Blood & Cancer. 60 (3): 371–376. doi:10.1002/PBC.24289. ISSN 1545-5009. PMC 5140272. PMID 22961750. Wikidata Q37478437.{{cite journal}}: CS1 maint: multiple names: authors list (link)
* Andrea Hayes-Jordan; Holly Green; Victor Prieto; Johannes E Wolff (1 April 2012). "Unusual cases: melanomatosis and nephroblastomatosis treated with hyperthermic intraperitoneal chemotherapy". Journal of Pediatric Surgery. 47 (4): 782–787. doi:10.1016/J.JPEDSURG.2011.12.018. ISSN 0022-3468. PMID 22498396. Wikidata Q38002223.
* Andrea Hayes-Jordan (1 February 2012). "Recent advances in non-rhabdomyosarcoma soft-tissue sarcomas". Seminars in pediatric surgery. 21 (1): 61–67. doi:10.1053/J.SEMPEDSURG.2011.10.006. ISSN 1055-8586. PMID 22248971. Wikidata Q37976208.
* Chelsea C Pinnix; Hiral P Fontanilla; Andrea Hayes-Jordan; et al. (19 November 2011). "Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery". International Journal of Radiation Oncology Biology Physics. 83 (1): 317–326. doi:10.1016/J.IJROBP.2011.06.1985. ISSN 0360-3016. PMC 4005898. PMID 22104361. Wikidata Q33398380.
* Andrea Hayes-Jordan; Peter M Anderson (1 July 2011). "The diagnosis and management of desmoplastic small round cell tumor: a review". Current Opinion in Oncology. 23 (4): 385–389. doi:10.1097/CCO.0B013E3283477AAB. ISSN 1040-8746. PMID 21577112. Wikidata Q37876163.
* Stacey Moore-Olufemi; Cynthia Herzog; Carla Warneke; et al. (1 June 2011). "Outcomes in pediatric melanoma: comparing prepubertal to adolescent pediatric patients". Annals of Surgery. 253 (6): 1211–1215. doi:10.1097/SLA.0B013E318217E852. ISSN 0003-4932. PMID 21451389. Wikidata Q37859591.
* Winston W Huh; Carrie Yuen; Mark Munsell; et al. (10 March 2011). "Liposarcoma in children and young adults: a multi-institutional experience". Pediatric Blood & Cancer. 57 (7): 1142–1146. doi:10.1002/PBC.23095. ISSN 1545-5009. PMC 3134599. PMID 21394894. Wikidata Q34627494.
* David O Walterhouse; Jane L Meza; John C Breneman; et al. (4 February 2011). "Local control and outcome in children with localized vaginal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma committee of the Children's Oncology Group". Pediatric Blood & Cancer. 57 (1): 76–83. doi:10.1002/PBC.22928. ISSN 1545-5009. PMC 3459820. PMID 21298768. Wikidata Q36284400.
* Phillip A Letourneau; Brett Shackett; Lianchun Xiao; Jonathan Trent; Kuo Jen Tsao; Kevin Lally; Andrea Hayes-Jordan (1 February 2011). "Resection of pulmonary metastases in pediatric patients with Ewing sarcoma improves survival". Journal of Pediatric Surgery. 46 (2): 332–335. doi:10.1016/J.JPEDSURG.2010.11.013. ISSN 0022-3468. PMC 3097027. PMID 21292083. Wikidata Q34989361.
* Feiyan Liu; Xiaolin Hu; Mary Zimmerman; Jennifer L Waller; Ping Wu; Andrea Hayes-Jordan; Dina Lev; Kebin Liu (17 January 2011). "TNFα cooperates with IFN-γ to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis". PLOS One. 6 (1): e16241. Bibcode:2011PLoSO...616241L. doi:10.1371/JOURNAL.PONE.0016241. ISSN 1932-6203. PMC 3022032. PMID 21264227. Wikidata Q33802588.
* Beverly Raney; Julie Stoner; James Anderson; et al. (1 November 2010). "Impact of tumor viability at second-look procedures performed before completing treatment on the Intergroup Rhabdomyosarcoma Study Group protocol IRS-IV, 1991-1997: a report from the children's oncology group". Journal of Pediatric Surgery. 45 (11): 2160–2168. doi:10.1016/J.JPEDSURG.2010.07.021. ISSN 0022-3468. PMC 3128803. PMID 21034938. Wikidata Q35084188.
* Suizhao Wang; Wenhong Ren; Jeffery Liu; et al. (20 April 2010). "TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in vivo". Clinical Cancer Research. 16 (9): 2591–2604. doi:10.1158/1078-0432.CCR-09-2443. ISSN 1078-0432. PMC 2967255. PMID 20406839. Wikidata Q34256933.
* Nathan D Allison; Christopher M Anderson; Shinil K Shah; Kevin P Lally; Andrea Hayes-Jordan; Kuo-Jen Tsao; Richard J Andrassy; Charles S Cox (1 October 2009). "Outcomes of truncal vascular injuries in children". Journal of Pediatric Surgery. 44 (10): 1958–1964. doi:10.1016/J.JPEDSURG.2009.01.005. ISSN 0022-3468. PMC 3086260. PMID 19853755. Wikidata Q34908328.
* Andrea Hayes-Jordan; Richard Andrassy (1 June 2009). "Rhabdomyosarcoma in children". Current Opinion in Pediatrics. 21 (3): 373–378. doi:10.1097/MOP.0B013E32832B4171. ISSN 1040-8703. PMID 19448544. Wikidata Q37485855.
* David A Rodeberg; Julie A Stoner; Andrea Hayes-Jordan; Simon C Kao; Suzanne L Wolden; Steve J Qualman; William H Meyer; Douglas S Hawkins (26 May 2009). "Prognostic significance of tumor response at the end of therapy in group III rhabdomyosarcoma: a report from the children's oncology group". Journal of Clinical Oncology. 27 (22): 3705–3711. doi:10.1200/JCO.2008.19.5933. ISSN 0732-183X. PMC 3020959. PMID 19470937. Wikidata Q34490071.
* Dafeng Yang; Suizhao Wang; Craig Brooks; et al. (1 February 2009). "IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression". Cancer Research. 69 (3): 1080–8. doi:10.1158/0008-5472.CAN-08-2520. ISSN 0008-5472. PMC 2633427. PMID 19155307. Wikidata Q24642376.
* Andrea Hayes-Jordan; Julie A Stoner; James R Anderson; et al. (1 May 2008). "The impact of surgical excision in chest wall rhabdomyosarcoma: a report from the Children's Oncology Group". Journal of Pediatric Surgery. 43 (5): 831–836. doi:10.1016/J.JPEDSURG.2007.12.021. ISSN 0022-3468. PMC 4646069. PMID 18485948. Wikidata Q36283032.
* Dolly Aguilera; Andrea Hayes-Jordan; Peter Anderson; Shiao Woo; Margaret Pearson; Holly Green (2008). "Outpatient and home chemotherapy with novel local control strategies in desmoplastic small round cell tumor". Sarcoma. 2008: 261589. doi:10.1155/2008/261589. ISSN 1357-714X. PMC 2430011. PMID 18566684. Wikidata Q21342824.
* Andrea Hayes-Jordan; Debra K Doherty; Sonlee D West; R Beverly Raney; Martin L Blakely; Charles S Cox; Richard J Andrassy; Kevin P Lally (1 April 2006). "Outcome after surgical resection of recurrent rhabdomyosarcoma". Journal of Pediatric Surgery. 41 (4): 633-8; discussion 633-8. doi:10.1016/J.JPEDSURG.2005.12.002. ISSN 0022-3468. PMID 16567168. Wikidata Q36433063.
* Andrea Hayes-Jordan (1 May 2005). "Surgical management of the incidentally identified ovarian mass". Seminars in pediatric surgery. 14 (2): 106–110. doi:10.1053/J.SEMPEDSURG.2005.01.006. ISSN 1055-8586. PMID 15846567. Wikidata Q36104546.