# 2016 Knoxville Challenger – Singles

Daniel Evans was the defending champion but lost in the second round to Peter Polansky.
Michael Mmoh won the title after defeating Polansky 7–5, 2–6, 6–1 in the final.

## Seeds

* Daniel Evans (second round)
* Frances Tiafoe (second round)
* Jared Donaldson (semifinals)
* Bjorn Fratangelo (first round)
* Denis Kudla (first round)
* Tim Smyczek (second round)
* Henri Laaksonen (first round)
* Stefan Kozlov (semifinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| | Peter Polansky | 6 | 6 | | | | |
| 3 | Jared Donaldson | 2 | 4 | | | | |
| 3 | Jared Donaldson | 2 | 4 | Peter Polansky | 5 | 6 | 1 |
| | | | | Michael Mmoh | 7 | 2 | 6 |
| 8 | Stefan Kozlov | 0 | 3 | Michael Mmoh | 7 | 2 | 6 |
| | Michael Mmoh | 6 | 6 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | D Evans | 6 | 6 | | | | | | | | | | | | | | | |
| | M Krueger | 2 | 3 | | 1 | D Evans | 6 | 6$^5$ | 2 | | | | | | | | | |
| | P Polansky | 6 | 6 | | | P Polansky | 1 | 7$^7$ | 6 | | | | | | | | | |
| Q | L Broady | 3 | 4 | | | | | | | | P Polansky | 6$^8$ | 6 | 5 | | | | |
| Q | D Cox | 2 | 2 | | | | | | | WC | M McDonald | 7$^{10}$ | 4 | 1$^r$ | | | | |
| WC | M McDonald | 6 | 6 | | WC | M McDonald | 6 | 6 | | | | | | | | | | |
| | D Novikov | 6 | 3 | 6 | | D Novikov | 4 | 1 | | | | | | | | | | |
| 5 | D Kudla | 4 | 6 | 4 | | | | | | | | | | | | P Polansky | 6 | 6 |
| 3 | J Donaldson | 6 | 6 | | | | | | | | | | | | 3 | J Donaldson | 2 | 4 |
| WC | M Lībietis | 2 | 4 | | 3 | J Donaldson | 6 | 7 | | | | | | | | | | |
| | S Bangoura | 3 | 6 | 4 | WC | R Williams | 4 | 5 | | | | | | | | | | |
| WC | R Williams | 6 | 2 | 6 | | | | | | 3 | J Donaldson | 6 | 5 | 6 | | | | |
| | R Bemelmans | 5 | 7$^7$ | 6 | | | | | | | R Bemelmans | 3 | 7 | 4 | | | | |
| | J De Loore | 7 | 6$^3$ | 4 | | R Bemelmans | 6 | 6 | | | | | | | | | | |
| | N Rubin | 6 | 6 | | | N Rubin | 4 | 4 | | | | | | | | | | |
| 7 | H Laaksonen | 3 | 3 | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | S Kozlov | 6 | 7 | | | | | | | | | | | | | | |
| Alt | S Barry | 4 | 5 | | 8 | S Kozlov | 6 | 6 | | | | | | | | | |
| | T Sandgren | 6 | 6 | | | T Sandgren | 2 | 4 | | | | | | | | | |
| Q | Jared Hiltzik | 4 | 3 | | | | | | | 8 | S Kozlov | 6 | 6 | | | | |
| | E Corrie | 7$^7$ | 2 | 6 | | | | | | | E Corrie | 4 | 3 | | | | |
| WC | R Sarmiento | 6$^5$ | 6 | 4 | | E Corrie | 3 | 6 | 7$^7$ | | | | | | | | |
| | S Groth | 7 | 4 | 6 | | S Groth | 6 | 3 | 6$^3$ | | | | | | | | |
| 4 | B Fratangelo | 5 | 6 | 2 | | | | | | | | | | 8 | S Kozlov | 0 | 3 |
| 6 | T Smyczek | 7$^7$ | 6 | | | | | | | | | | | | M Mmoh | 6 | 6 |
| LL | T van Rijthoven | 6$^2$ | 4 | | 6 | T Smyczek | 3 | 2 | | | | | | | | | |
| Q | Y Bhambri | 4 | 6$^8$ | | | M Mmoh | 6 | 6 | | | | | | | | | |
| | M Mmoh | 6 | 7$^{10}$ | | | | | | | | M Mmoh | 6 | 6 | | | | |
| | B Baker | 6 | 2 | 6$^4$ | | | | | | | A Krajicek | 4 | 4 | | | | |
| | A Krajicek | 4 | 6 | 7$^7$ | | A Krajicek | 6 | 3 | 6 | | | | | | | | |
| | B Klein | 6 | 5 | 1 | 2 | F Tiafoe | 3 | 6 | 3 | | | | | | | | |
| 2 | F Tiafoe | 3 | 7 | 6 | | | | | | | | | | | | | |