# List of Late Night with Jimmy Fallon episodes (2010)

This is the list of episodes for Late Night with Jimmy Fallon in 2010.

## 2010
### January

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 173 | January 4, 2010 (2010-01-04) | Bill Hader, Fred Willard | Japandroids |
| ?uestions, Cell Phone Shootout ||||
| 174 | January 5, 2010 (2010-01-05) | Michael Cera, Ana Gasteyer | Shwayze |
| Wheel Of Carpet Samples, Taboo - Michael Cera ||||
| 175 | January 6, 2010 (2010-01-06) | Ethan Hawke, Gabourey Sidibe | Clipse |
| Post-Apocalyptic Andy Rooney, Celebrity Man Boobs, Three-Point Shootout with Ethan Hawke ||||
| 176 | January 7, 2010 (2010-01-07) | Amy Adams, John Oliver | Fela |
| New Velvet Elvises, Bull Riding Lessons, Karaoke Time - Amy Adams ||||
| 177 | January 8, 2010 (2010-01-08) | Matthew Broderick, Ashley Greene | Nick Jonas and the Administration ("Who I Am") |
| Thank You Notes, Dance Your Hat And Gloves Off ||||
| 178 | January 11, 2010 (2010-01-11) | Maggie Gyllenhaal, David Ortiz | Lenny Clarke |
| Obama Expressions, Competitive Spit Takes ||||
| 179 | January 12, 2010 (2010-01-12) | Ringo Starr | Ringo Starr |
| Freestylin' With The Roots ||||
| 180 | January 13, 2010 (2010-01-13) | Freddie Prinze Jr., Anthony Anderson | Kesha ("Tik Tok") |
| Head Swap, Air Drum Challenge ||||
| 181 | January 14, 2010 (2010-01-14) | Sigourney Weaver, Jeremy Renner | Loudon Wainwright III |
| Neil Young covers Pants on the Ground, Who Cares Hindenburg, Ultimate Mustache Fighter 4 "Hell's Unshaven" - Brimley Vs. 80's Bird, Beer Pong - Sigourney Weaver ||||
| 182 | January 15, 2010 (2010-01-15) | Kiefer Sutherland, Kerry Washington | Hotrats ("Queen Bitch") |
| Thank You Notes, Hot Dog In A Hole - Fox News Edition ||||
| 183 | January 18, 2010 (2010-01-18) | Ashley Judd, Jimmie Johnson | The Cribs |
| Shout Outs, Video Vision - Fire Safety, Bumper Car Race ||||
| 184 | January 19, 2010 (2010-01-19) | Randy Jackson, Paul Teutul Sr. | The Mountain Goats |
| iPhone Apps, Product Placement Preacher ||||
| 185 | January 20, 2010 (2010-01-20) | Tom Brokaw, Richard Belzer, Kerry Rhodes | Switchfoot |
| Obama's Angel and Devil, Audience Suggestion Box ||||
| 186 | January 21, 2010 (2010-01-21) | Queen Latifah, Rose Byrne | Fela! |
| Lick It For $10 - Winter Games Edition, Late Night Charades with Queen Latifah ||||
| 187 | January 22, 2010 (2010-01-22) | Brendan Fraser, Tracey Ullman | Beach House |
| A Tribute to Conan O'Brien At Studio 6A, Thank You Notes, Biathlon ||||

### February

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 188 | February 1, 2010 (2010-02-01) | Rosario Dawson, Tony Siragusa | New Kids on the Block |
| 6-bee, Cell Phone Shootout ||||
| 189 | February 2, 2010 (2010-02-02) | Meredith Vieira, Jesse Tyler Ferguson | Motion City Soundtrack |
| Kirk's Groundhog Day Song, Competitive Spit Takes, Snowball Throwing Contest ||||
| 190 | February 3, 2010 (2010-02-03) | Jessica Alba, Michael Strahan | Harper Simon |
| ?uestions, Dance Your Hat And Gloves Off, Beer Pong - Jessica Alba ||||
| 191 | February 4, 2010 (2010-02-04) | Channing Tatum, Aubrey Plaza | Hot Chip |
| TV Show Mash-Ups, Freestylin' With The Roots, Three-Point Shootout with Channing Tatum ||||
| 192 | February 5, 2010 (2010-02-05) | Brian Williams, Amanda Seyfried | Sean Patton |
| Slow Jam The News with Brian Williams, Thank You Notes, Grad Students Super Bowl ||||
| 193 | February 8, 2010 (2010-02-08) | Stephen Colbert, Willie Garson | Éric Ripert |
| Late Preview, Late Night Recognizes The Olympics - Snow Bobbing, Tea Party Karaoke ||||
| 194 | February 9, 2010 (2010-02-09) | Jeff Musial, Bill Paxton, James Van Der Beek | Regina Spektor |
| Spider-Man & Superman Brothers Breakdance, Late Night Recognizes The Olympics - Ski Boot Power Walking, Jeff Musial's Animals ||||
| 195 | February 10, 2010 (2010-02-10) | Dick Cavett, Christian Siriano | Yeasayer |
| Late Night Recognizes The Olympics - Finger Skating, Product Placement Preacher ||||
| 196 | February 11, 2010 (2010-02-11) | John Lithgow, Jessica Szohr | Neon Indian |
| Robert is Bothered, Cougar Hunting Song, Late Trailer ||||
| 197 | February 12, 2010 (2010-02-12) | Benicio del Toro, Selena Gomez, Kim Kardashian, Reggie Bush | Selena Gomez & the Scene ("Naturally") |
| Thank You Notes, Late - Episode 1 ||||

### March

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 198 | March 1, 2010 (2010-03-01) | Robert Pattinson, Judah Friedlander | Mario Batali |
| Anniversary Song - Freshman 15, Late - Episode 2, Robert Is Bothered ||||
| 199 | March 2, 2010 (2010-03-02) | Wesley Snipes, Emilie de Ravin | Ludacris ("How Low") |
| Shout Outs, Ultimate Mustache Fighter 5 "Mucho Macho Mayhem" - '70s Reynolds Vs. '80s Selleck, Three-Point Shootout with Wesley Snipes ||||
| 200 | March 3, 2010 (2010-03-03) | Barbara Walters, Regina King | Erykah Badu |
| Video Vision - Sexual Harassment, Audience Suggestion Box ||||
| 201 | March 4, 2010 (2010-03-04) | Zach Galifianakis, Mia Wasikowska | Silversun Pickups |
| California Dreams Reunion, Let Us Play with Your Look ||||
| 202 | March 5, 2010 (2010-03-05) | Mike Myers, Matt Lucas | Joanna Newsom |
| Thank You Notes, Winds Of War, Mike's Canada Corner ||||
| 203 | March 8, 2010 (2010-03-08) | Abigail Breslin, Chris Parnell | Ted Leo and the Pharmacists |
| Who Cares Hindenburg, Freestylin' With The Roots, Lazy Sunday ||||
| 204 | March 9, 2010 (2010-03-09) | Chelsea Handler, Matt Walsh | Allman Brothers ("Whipping Post") |
| President Of The Audience, Martini Race (Jimmy Fallon Cuts Hand) ||||
| 205 | March 10, 2010 (2010-03-10) | Forest Whitaker, Rachael Harris | The National |
| Letters Home, Blimp Race ||||
| 206 | March 11, 2010 (2010-03-11) | Michael Moore, Chris Hardwick | Broken Bells ("Holiday") |
| Eric Massa's Larry King Interview Outtakes, Dancing On Air ||||
| 207 | March 12, 2010 (2010-03-12) | Parker Posey, Jason Sudeikis | Vampire Weekend |
| Thank You Letters, Cell Phone Shootout, Jimmy and Parker Dance-Off ||||
| 208 | March 15, 2010 (2010-03-15) | Julianne Moore, Toni Collette | Freeway |
| Obama Expressions, Late Night Charades with Julianne Moore & Toni Collette, Late Promo ||||
| 209 | March 16, 2010 (2010-03-16) | Kristen Stewart, Bee Gees, Dr. Drew Pinsky | The Script ("Breakeven") |
| Late - Episode 3 ||||
| 210 | March 17, 2010 (2010-03-17) | Dakota Fanning, Joseph Fiennes | The XX |
| Siena Saints Support, Irish Spring Breaker Song, Wheel Of Carpet Samples ||||
| 211 | March 18, 2010 (2010-03-18) | Lucy Liu, Gene Simmons | Universal Record Database |
| Go Siena Go, Dance Your Hat And Gloves Off, Beer Pong - Lucy Liu ||||
| 212 | March 19, 2010 (2010-03-19) | Ted Danson, Kara DioGuardi | Air |
| Thank You Notes, Siena Wrap-Up, Battle Of The Instant Bands, Ted Danson Boring Interview ||||
| 213 | March 22, 2010 (2010-03-22) | Alicia Silverstone, Mark Valley | Rogue Wave |
| Parliamentary Procedure, Hot Dog In A Hole - Health Care Heroes Edition, Rockapella, Fake Fighting Lesson with Mark Valley ||||
| 214 | March 23, 2010 (2010-03-23) | Janet Jackson, John Cena | The Besnard Lakes |
| Pros & Cons - Health Care Reform, Competitive Spit Takes ||||
| 215 | March 24, 2010 (2010-03-24) | Ben Stiller, Hoda Kotb | Clientele |
| Big Effing Deal Bill, ?uestions, Health Care Hits Karaoke ||||
| 216 | March 25, 2010 (2010-03-25) | Liev Schreiber, Rob Corddry | Robert Randolph ("Purple Haze") |
| Freestylin' With The Roots, Audience Suggestion Box ||||
| 217 | March 26, 2010 (2010-03-26) | Bryan Cranston, Jill Scott | Morgan Murphy |
| Thank You Notes, Beef Solvers ||||
| 218 | March 29, 2010 (2010-03-29) | Jeff Goldblum, Jennifer Morrison | Julian Casablancas |
| Slow Jam The News with Brian Williams, Ultimate Mustache Fighter 6 - Santana Vs. Oates ||||
| 219 | March 30, 2010 (2010-03-30) | Fred Armisen, Chuck Liddell | Moshe Kasher |
| Late - Episode 4, Chuck Liddell Choke Hold Lesson ||||
| 220 | March 31, 2010 (2010-03-31) | Tyler Perry, Dan Dunn's Paint Jam | Drive-By Truckers |
| Pros & Cons - Dancing With The Stars, Dancing On Air, Remote Control Blimp Race ||||

### April

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 221 | April 1, 2010 (2010-04-01) | Ricky Gervais, Anthony Mackie | Easton Corbin ("A Little More Country Than That") |
| iPhone Apps, Put It In Reverse ||||
| 222 | April 2, 2010 (2010-04-02) | Sam Worthington, Joshua Topolsky | Liquid Liquid |
| Thank You Notes, Rejected "Clash of the Titans" Catchphrases, A Look At The iPad ||||
| 223 | April 5, 2010 (2010-04-05) | Jeff Musial, Bob Costas, James Badge Dale | Peter Wolf with Shelby Lynne |
| Dancing With The Cardboard Cutouts Of The Stars, Jeff Musial's Animals ||||
| 224 | April 6, 2010 (2010-04-06) | Christopher Meloni, Taraji P. Henson | Dr. Dog |
| Pros & Cons - Tiger Woods' Return To Golf, Kate Gosselin's Paparazzi Dance, Three-Point Shootout with Christopher Meloni ||||
| 225 | April 7, 2010 (2010-04-07) | Rachel Maddow, The Mighty Boosh, Dave Annable | Suzanne Vega |
| Who Cares Hindenburg, Battle Of The Instant Bands, Mixing Drinks with Rachel Maddow ||||
| 226 | April 8, 2010 (2010-04-08) | Tina Fey, Justin Bieber | Mario Batali |
| 6-bee, Late Night Charades - Fallon & Fey Vs. Amy Poehler & Seth Meyers ||||
| 227 | April 9, 2010 (2010-04-09) | Jeff Daniels, Olivia Munn | Black Rebel Motorcycle Club |
| Thank You Notes, Cell Phone Shootout ||||
| 228 | April 12, 2010 (2010-04-12) | Alan Cumming, Greta Gerwig, Cliff Bleszinski | Baron Vaughn |
| Tiger Woods Giraffe Song, Freestylin' With The Roots, Gears Of War 3 World Premiere Trailer - "Ashes To Ashes" ||||
| 229 | April 13, 2010 (2010-04-13) | Kelly Ripa, Eric Stonestreet | The Specials ("A Message to You, Rudy") |
| Pros & Cons - KFC Double Down Sandwich, Competitive Spit Takes, Beer Pong - Kelly Ripa ||||
| 230 | April 14, 2010 (2010-04-14) | Stevie Starr, Michael J. Fox, Green Day | Kaki King |
| Spanx But No Spanx ||||
| 231 | April 15, 2010 (2010-04-15) | Chris Rock, Emma Stone | The Unseen |
| Shout Outs, Say What!? ||||
| 232 | April 16, 2010 (2010-04-16) | Tracy Morgan, Kevin Rose, Alex Albrecht, Ndamukong Suh | The Flaming Lips with Stardeath and White Dwarfs ("Breathe") |
| Thank You Notes, Strait No Chaser performs medley of TGIF theme songs ||||
| 233 | April 26, 2010 (2010-04-26) | Kathie Lee Gifford, Brian Posehn | Gogol Bordello |
| Hubble Gotchu, Letters Home, Identify That Ditty with Kathie Lee Gifford ||||
| 234 | April 27, 2010 (2010-04-27) | Brendan Fraser, Rebecca Hall | The Whigs |
| Pros & Cons - Kentucky Derby, Dance Your Hat And Gloves Off ||||
| 235 | April 28, 2010 (2010-04-28) | Michael Caine, Mary Lynn Rajskub | Sharon Jones & the Dap-Kings |
| Late - Episode 5 ||||
| 236 | April 29, 2010 (2010-04-29) | Ed Burns, Jackie Earle Haley | Paramore |
| Shared Experiences, Skittles - Fallon Vs. Burns ||||
| 237 | April 30, 2010 (2010-04-30) | Gwyneth Paltrow, Colin Quinn | Jabbawockeez |
| Thank You Notes, Battle Of The Instant Bands, The Best Of Shazzazz ||||

### May

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 238 | May 3, 2010 (2010-05-03) | Sarah Silverman, Joan Rivers | Corinne Bailey Rae |
| Wheel Of Carpet Samples, Let Us Play With Your Look ||||
| 239 | May 4, 2010 (2010-05-04) | Ellen Pompeo, Lea Michele | OK Go |
| Pros & Cons - Cinco De Mayo, Put It In Reverse ||||
| 240 | May 5, 2010 (2010-05-05) | Joel McHale, Nina Dobrev, Roger Waters | The New Pornographers |
| Big Heads, Spanx But No Spanx ||||
| 241 | May 6, 2010 (2010-05-06) | Betty White, Oliver Platt | Pete Holmes |
| New Velvet Elvises, Beer Pong - Betty White ||||
| 242 | May 7, 2010 (2010-05-07) | Maya Rudolph, Common | Court Yard Hounds |
| Thank You Notes, Cell Phone Shootout, Karaoke Time - Maya Rudolph ||||
| 243 | May 10, 2010 (2010-05-10) | Kristen Wiig, Jim Cramer | Green Day ("Rip This Joint"), Taj Mahal ("Shine a Light") |
| Lick It For $10 - Rolling Stones Edition ||||
| 244 | May 11, 2010 (2010-05-11) | Evangeline Lilly, Kenan Thompson | Keith Urban ("Tumbling Dice") |
| Late - Episode 6, Intense Lost Questions ||||
| 245 | May 12, 2010 (2010-05-12) | Queen Latifah, Sheryl Crow | Sheryl Crow ("All Down the Line") |
| Pros & Cons - Re-release of Exile on Main St., Robert Is Bothered, Three-Point Shootout with Queen Latifah ||||
| 246 | May 13, 2010 (2010-05-13) | Keith Richards, LL Cool J, Sam Rockwell | Phish ("Loving Cup") |
| Freestylin' With The Roots, featuring Dr. John ||||
| 247 | May 14, 2010 (2010-05-14) | Stones in Exile | N/A |
| World Premiere of Stones in Exile ||||
| 248 | May 17, 2010 (2010-05-17) | Randy Jackson, David Boreanaz, Russell Hantz, Parvati Shallow, Sandra Diaz-Twine | Public Image Ltd |
| Competitive Spit Takes ||||
| 249 | May 18, 2010 (2010-05-18) | Matthew Fox, Jane Lynch | Ray Wylie Hubbard |
| Pros & Cons - Outdoor Summer Concert Festivals, Ladysmith Snack Mambazo - Hot Pockets, Intense Lost Questions, Late Promo ||||
| 250 | May 19, 2010 (2010-05-19) | Jerry Seinfeld, Jesse Eisenberg | Mumford & Sons |
| Slow Jam The News with Brian Williams, Hubble Gotchu ||||
| 251 | May 20, 2010 (2010-05-20) | Will Forte, Jim Parsons | John Delucie |
| Late - Episode 7, Will Forte's MacGruber Song ||||
| 252 | May 21, 2010 (2010-05-21) | Donald Trump, Jorge Garcia | Robbie Dupree ("Steal Away") |
| Yacht Rock 2010, Shared Experiences, Thank You Notes, Yacht Race, Intense Lost Questions ||||
| 253 | May 24, 2010 (2010-05-24) | Sir Ben Kingsley, Rosemarie DeWitt | Kumail Nanjiani |
| Obama Expressions, Say What!?, Space Train - Sir Ben Kingsley ||||
| 254 | May 25, 2010 (2010-05-25) | Kim Cattrall, Dana White | Frightened Rabbit |
| Pros & Cons - American Idol Finale, Think About It, Sex And The City 2 Screen Test ||||
| 255 | May 26, 2010 (2010-05-26) | Jake Gyllenhaal, Mario Cantone | The Black Keys |
| Cold Opening with Dr. Oz, Shout Outs, American Idol Hedgehog Song, Mario Cantone sings Route 66 ||||
| 256 | May 27, 2010 (2010-05-27) | Jeff Musial, Ann Curry, JoAnn & Steve Ward | Talib Kweli and Hi-Tek as Reflection Eternal |
| Remix The Clips, Jeff Musial's Animals, Out Of Bounds with Steve & JoAnn Ward ||||
| 257 | May 28, 2010 (2010-05-28) | Ice Cube, Gemma Arterton | Stars |
| Thank You Notes, Audience Suggestion Box, Jimmy Sings "Balls in Your Mouth" ||||

### June

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 258 | June 7, 2010 (2010-06-07) | Molly Shannon, Chris Colfer, Ian Poulter | Kings of Convenience |
| iPhone Apps, Tiger Woods PGA TOUR 2011 Demo ||||
| 259 | June 8, 2010 (2010-06-08) | Holly Hunter, Lee DeWyze | Circa Survive |
| Pros & Cons - Going To The Beach, Cell Phone Shootout, BP Oil Spill Song ||||
| 260 | June 9, 2010 (2010-06-09) | Jessica Biel, Craig Robinson | Phish |
| Jimmy Waves Back to Craig Ferguson, ?uestions, Battle Of The Instant Bands, Tandem Bike Ride with Jessica Biel ||||
| 261 | June 10, 2010 (2010-06-10) | John C. Reilly, Justin Bartha, Brendan Hunt | Sarah McLachlan |
| Remix The Clips, Dance Your Hat And Gloves Off, John C. Reilly Is Not Steve Brule ||||
| 262 | June 11, 2010 (2010-06-11) | Bradley Cooper, Robin Antin | Dave Arnold & Nils Norén |
| Thank You Notes, Put It In Reverse ||||
| 263 | June 14, 2010 (2010-06-14) | Joy Behar, Carson Kressley | Gail Simmons |
| Kirk's Flag Day Song, Video Vision - Finding A Hobby ||||
| 264 | June 15, 2010 (2010-06-15) | Cedric the Entertainer, Fred Willard | Broken Social Scene |
| Pros & Cons - Watching The World Cup, World Cup Commentators, Cedric the Entertainer Entertains ||||
| 265 | June 16, 2010 (2010-06-16) | Lisa Kudrow, Big Show | The Gaslight Anthem |
| Who Cares Hindenburg, Wheel Of Carpet Samples, Late Night Charades Fallon Vs. Kudrow ||||
| 266 | June 17, 2010 (2010-06-17) | Seth Meyers, Bethenny Frankel | Blitzen Trapper |
| Remix The Clips, Competitive Spit Takes, Seth and Josh Meyers "Brother Trivia" ||||
| 267 | June 18, 2010 (2010-06-18) | Kate Walsh, Jim Breuer | The Roots featuring Yim Yames |
| Thank You Notes, Freestylin' With The Roots ||||
| 268 | June 21, 2010 (2010-06-21) | Jada Pinkett Smith, Miranda Cosgrove, Microsoft Kinect | Travie McCoy ("Billionaire") |
| Robert is Bothered, Ladysmith Snack Mambazo - Ben & Jerry's, Microsoft Kinect Demo ||||
| 269 | June 22, 2010 (2010-06-22) | Salma Hayek Pinault, Jeffrey Donovan, Call of Duty: Black Ops | Herbie Hancock ("Imagine") |
| Slow Jam The News with Brian Williams, Pros & Cons - Wimbledon, Call Of Duty: Black Ops Demo ||||
| 270 | June 23, 2010 (2010-06-23) | Heidi Klum, Joshua Topolsky, Need for Speed: Hot Pursuit | Macy Gray |
| At The Bar with Roger Federer, Audience Suggestion Box, BP Oil Spill Song, Need For Speed: Hot Pursuit Demo ||||
| 271 | June 24, 2010 (2010-06-24) | David Spade, Beth Ostrosky Stern, Killzone 3 | MGMT |
| 7th Floor West - Episode 13, Killzone 3 Demo ||||
| 272 | June 25, 2010 (2010-06-25) | Adam Sandler, Oliver Stone, David Chang, Donkey Kong Country Returns | Eminem ("Won't Back Down") |
| Thank You Notes, Donkey Kong Country Returns Demo ||||

### July

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 273 | July 12, 2010 (2010-07-12) | Eddie Izzard, Angie Harmon | Big Boi |
| Shout Outs, Cell Phone Shootout ||||
| 274 | July 13, 2010 (2010-07-13) | Nicolas Cage, Jennifer Lawrence | Squeeze |
| Pros & Cons - Summer Family BBQs, Audience Artwork ||||
| 275 | July 14, 2010 (2010-07-14) | Martha Stewart, Jack McBrayer | Paper Tongues ("Ride to California") |
| Twitter Song - Black Thought's Favorite Dinosaurs, Dancing On Air ||||
| 276 | July 15, 2010 (2010-07-15) | Jennifer Love Hewitt, John Henson, Thierry Henry | Million Dollar Quartet |
| Remix The Clips, Ultimate Mustache Fighter 7 - Dr. Phil Vs. Oates, Shots On Goal with Thierry Henry ||||
| 277 | July 16, 2010 (2010-07-16) | Joseph Gordon-Levitt, Piper Perabo | Kurt Metzger |
| Thank You Notes, Say What!? ||||
| 278 | July 19, 2010 (2010-07-19) | Horatio Sanz | Widespread Panic |
| Late Night Hashtags - #whydonttheymakethat, Freestylin' With The Roots, Horatio's Larry King Audition ||||
| 279 | July 20, 2010 (2010-07-20) | Zach Braff, Jemaine Clement | Crowded House |
| Pros & Cons - Summer Camp, Mel Gibson Karaoke ||||
| 280 | July 21, 2010 (2010-07-21) | Steve Carell, Selena Gomez | Halestorm |
| Obama Expressions, Audience Suggestion Box, BP Oil Spill Song ||||
| 281 | July 22, 2010 (2010-07-22) | Kevin Connolly, Christina Hendricks | Sheryl Crow |
| Remix The Clips, And The Winner Is, Three-Point Shootout with Kevin Connolly ||||
| 282 | July 23, 2010 (2010-07-23) | January Jones, Susie Essman | Rick Ross |
| Thank You Notes, Competitive Spit Takes, Beer Pong - January Jones ||||
| 283 | July 26, 2010 (2010-07-26) | Kevin Kline, Chace Crawford | Hanson |
| He Said She Said, Wheel of Carpet Samples ||||
| 284 | July 27, 2010 (2010-07-27) | Rachel Weisz, Chris Bosh | Angélique Kidjo featuring John Legend ("Move On Up") |
| Pros & Cons - The New Season of Jersey Shore, 7th Floor West - Episode 14, One On One with Chris Bosh ||||
| 285 | July 28, 2010 (2010-07-28) | Luke Wilson, Tommy Davidson, Universal Record Database | Dierks Bentley |
| Late Night Hashtags - #ifihadasuperpower, Universal Record Attempts ||||
| 286 | July 29, 2010 (2010-07-29) | 50 Cent, Lucy Punch | Of Montreal featuring Solange ("Sex Karma") |
| Remix The Clips, Neil Young sings Double Rainbow ||||
| 287 | July 30, 2010 (2010-07-30) | Paul Rudd, Jordana Spiro | Green Day ("Last of the American Girls") |
| Thank You Notes, Dance Your Hat And Gloves Off ||||

### August

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 288 | August 2, 2010 (2010-08-02) | Kathy Griffin, Adam McKay | Trey Songz |
| New Velvet Elvises, Hubble Gotchu ||||
| 289 | August 3, 2010 (2010-08-03) | Samuel L. Jackson, Giovanni Ribisi | Spoon |
| Pros & Cons - Shark Week, Put It In Reverse ||||
| 290 | August 4, 2010 (2010-08-04) | Will Ferrell, Tim DeKay | Mike Posner ("Cooler Than Me") |
| Late Night Hashtags - #myparentsareweird, Jacob's Patience ||||
| 291 | August 5, 2010 (2010-08-05) | Denis Leary, Connie Britton | Titus Andronicus |
| Remix The Clips, Summer Do Not Read List, Air Hockey - Jimmy vs. Denis Leary ||||
| 292 | August 6, 2010 (2010-08-06) | Billy Crudup, J. B. Smoove | Step Up 3D Dancers |
| Thank You Notes, iPhone Apps, Late Night Golf Invitational with Billy Crudup ||||
| 293 | August 9, 2010 (2010-08-09) | Jason Bateman, Kieran Culkin, China Chow | Menomena |
| Cell Phone Shootout ||||
| 294 | August 10, 2010 (2010-08-10) | Dylan McDermott, Perez Hilton | Slayer |
| JetBlue Song - The Ballad of Steven Slater, Pros & Cons - Madden 2011, Perez Hilton's Found Footage of Steven Slater, Office Ukulele ||||
| 295 | August 11, 2010 (2010-08-11) | Michael Cera, Landon Donovan | JP, Chrissie & the Fairground Boys |
| Late Night Hashtags - #thereshouldbealaw, JetBlue Song - The Ballad of Steven Slater, Ladysmith Snack (Theme Park) Mambazo - Six Flags, Late Night Charades with Michael Cera, FIFA Soccer 11 with Landon Donovan ||||
| 296 | August 12, 2010 (2010-08-12) | Mickey Rourke, The Kids in the Hall | Walkmen |
| Remix The Clips, 7th Floor West - Episode 15 ||||
| 297 | August 13, 2010 (2010-08-13) | Gabourey Sidibe, Aubrey Plaza | Bobby Slayton |
| Thank You Notes, JetBlue Song - The Ballad of Steven Slater, Battle Of The Instant Bands, Beer Pong - Gabourey Sidibe ||||
| 298 | August 30, 2010 (2010-08-30) | The Best of Late Night with Jimmy Fallon | N/A |
| 6-bee, The Best Of Late, Robert Is Bothered, Head Swap, The Real Housewives of Late Night - Episode 5, Susan Boyle Reaction ||||
| 299 | August 31, 2010 (2010-08-31) | Drew Barrymore, Snoop Dogg | Black Mountain |
| Pros & Cons - Hosting The Emmys, Let Us Play With Your Look, Total Iceholes ||||

### September

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 300 | September 1, 2010 (2010-09-01) | Anna Wintour, Marc Jacobs, John Cena | Yo Gabba Gabba! ("Spirit of the Boogie") |
| Twitter Song - I Love Your Elbows, Competitive Spit Takes ||||
| 301 | September 2, 2010 (2010-09-02) | Rachel Maddow, Jon Glaser | Heart |
| Play Guitar with Pavement Contest Announcement, Remix The Clips, Dance Your Hat And Gloves Off, Mixing Drinks with Rachel Maddow ||||
| 302 | September 3, 2010 (2010-09-03) | Wendy Williams, Amber Riley | Never Shout Never |
| Thank You Notes, Freestylin' With The Roots, Ask Wendy ||||
| 303 | September 7, 2010 (2010-09-07) | Ashley Tisdale, Margaret Cho | Robert Randolph and the Family Band ("Walk Don't Walk") |
| Pros & Cons - Football Season, At The Bar with Roger Federer ||||
| 304 | September 8, 2010 (2010-09-08) | Elijah Wood, Maggie Q | Andy Haynes |
| Late Night Hashtags - #myroommateisweird, Do Not Read List, Stump Game with Elijah Wood ||||
| 305 | September 9, 2010 (2010-09-09) | Ali Larter, Mario Batali | Jerry Lee Lewis |
| Remix The Clips, Put It In Reverse ||||
| 306 | September 10, 2010 (2010-09-10) | Nathan Lane, Kris Jenner, Khloé Kardashian, Kim Kardashian | Chris Gethard |
| Thank You Notes, Kardashians Family Game ||||
| 307 | September 13, 2010 (2010-09-13) | Christina Ricci, Robert Plant | Memphis |
| Video Vision - Sports Fan, Cell Phone Shootout ||||
| 308 | September 14, 2010 (2010-09-14) | Justin Long, Tommy Hilfiger | Promises, Promises |
| Play Guitar with Pavement Contest Update, Pros & Cons - Freshmen Year In College, Dancing On Air ||||
| 309 | September 15, 2010 (2010-09-15) | Regis Philbin, Emma Stone | American Idiot |
| Late Night Hashtags - #icantbelieveididthat, Shared Experiences, Regis Philbin Sings ||||
| 310 | September 16, 2010 (2010-09-16) | Jon Hamm, Amy Ryan | Bloody Bloody Andrew Jackson |
| Remix The Clips, Name That Guy, Football Poker with Jon Hamm ||||
| 311 | September 17, 2010 (2010-09-17) | Will Arnett, Jason Ritter | Patti LuPone |
| Thank You Notes, Late Night Golf Invitational with Will Arnett ||||
| 312 | September 20, 2010 (2010-09-20) | Julianna Margulies, Cory Monteith | Superchunk |
| Monkey Shoot, Audience Suggestion Box, Musical Instrument Game - Fallon Vs. Margulies ||||
| 313 | September 21, 2010 (2010-09-21) | Tina Fey, Colin Hanks | Robert Plant, Band of Joy |
| Pros & Cons - Fall TV Premieres, Shout Outs, Late Night Charades - Fallon & Fey Vs. Higgins & Hanks ||||
| 314 | September 22, 2010 (2010-09-22) | Jeff Musial, Josh Brolin, Ben Rappaport | Kerry Simon |
| Late Night Hashtags - #ifihadonewish, Jeff Musial's Animals ||||
| 315 | September 23, 2010 (2010-09-23) | Amy Poehler, Rashida Jones, Aaron Johnson | Pavement |
| Remix the Clips ||||
| 316 | September 24, 2010 (2010-09-24) | Kristin Chenoweth, Super Grover 2.0 | John Legend and The Roots |
| Slow Jam The News, Reflections With Justin Bieber, Thank You Notes ||||
| 317 | September 27, 2010 (2010-09-27) | Susan Sarandon, Andrew Garfield | The Temper Trap |
| 7th Floor West - FINALE, Models & Buckets ||||
| 318 | September 28, 2010 (2010-09-28) | Christopher Meloni, JoAnna Garcia | Teenage Fanclub |
| Pros & Cons - The Gym, Freestyling With The Roots, Water War - Fallon Vs. Meloni ||||
| 319 | September 29, 2010 (2010-09-29) | Justin Timberlake, Jann Wenner | Belle and Sebastian |
| Late Night Hashtags - #worstjobieverhad, Tuba Gooding Jr. CD, History of Rap 1 ||||
| 320 | September 30, 2010 (2010-09-30) | Bryan Cranston, Jesse Eisenberg, Joshua Topolsky | The Vaselines |
| Remix The Clips, How You Like Me Now? ||||

### October

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 321 | October 1, 2010 (2010-10-01) | Helen Mirren, Aaron Sorkin | Anthony Jeselnik |
| Thank You Notes, Audience Craigslist Items, Beer Pong - Fallon Vs. Mirren ||||
| 322 | October 4, 2010 (2010-10-04) | Morgan Freeman, Josh Lucas | Gayngs |
| He Said She Said, Teleprompter Limbo - Jersey Shore ||||
| 323 | October 5, 2010 (2010-10-05) | Tom Selleck, Anthony Bourdain | Trace Adkins |
| Pros & Cons - 2010 MLB Postseason, Do Not Read List ||||
| 324 | October 6, 2010 (2010-10-06) | Diane Lane, Peter Sagal, Carl Kasell | Fistful of Mercy |
| Late Night Hashtags - #mycoworkerisweird, Baby Bird, Total Iceholes ||||
| 325 | October 7, 2010 (2010-10-07) | Jane Lynch, Emma Roberts | Pete Yorn |
| Remix The Clips, Wheel Of Carpet Samples ||||
| 326 | October 8, 2010 (2010-10-08) | Naomi Watts, Nick Swardson | Alton Brown |
| Thank You Notes, Battle of the Instant Bands ||||
| 327 | October 11, 2010 (2010-10-11) | Donald Trump, Sam Rockwell | Brad |
| iPhone Apps, Photo Machine Match Game ||||
| 328 | October 12, 2010 (2010-10-12) | Johnny Knoxville, Judah Friedlander | Everest |
| Pros & Cons - Obama's MTV Youth Town Hall Special, Ultimate Mustache Fighter 8 - Einstein Vs. Richie ||||
| 329 | October 13, 2010 (2010-10-13) | Whoopi Goldberg, Kevin O'Connor, Tom Silva, Richard Trethewey, Roger Cook | My Morning Jacket |
| Late Night Hashtags - #thatwouldbeawesome, Reflections With Justin Bieber ||||
| 330 | October 14, 2010 (2010-10-14) | Steve-O, Pee-wee Herman, Nick Hornby, Joy Bryant | Ben Folds |
| Remix the Clips ||||
| 331 | October 15, 2010 (2010-10-15) | Edward Norton, Bam Margera | Nick Vatterott |
| Thank You Notes, Tank Tops Talk Show ||||
| 332 | October 25, 2010 (2010-10-25) | Molly Shannon, Paul Scheer | Norah Jones |
| Obama Expressions, Dance Your Hat & Gloves Off, Charades - Fallon Vs. Shannon ||||
| 333 | October 26, 2010 (2010-10-26) | Joan Rivers, Juliette Lewis | Underworld |
| Pros & Cons - Halloween Parties, Competitive Spit Takes ||||
| 334 | October 27, 2010 (2010-10-27) | Alan Cumming, Donnie Wahlberg, Rich Little | School of Seven Bells |
| If Puppies Could Vote, Models & Buckets ||||
| 335 | October 28, 2010 (2010-10-28) | Dana Carvey, Jason Hawes, Grant Wilson | GWAR |
| Remix The Clips, Head Swap ||||
| 336 | October 29, 2010 (2010-10-29) | Laura Linney, Josh Charles | Ming Tsai |
| Thank You Notes, If Puppies Could Vote, Put It In Reverse, Elevator Dodgeball - Jimmy Fallon & Chris Canty Vs. Josh Charles & Jon Hamm ||||

### November

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 337 | November 1, 2010 (2010-11-01) | Jonah Hill, Russell Simmons | Jonathan Richman |
| If Puppies Could Vote, Shoutouts ||||
| 338 | November 3, 2010 (2010-11-03) | Zach Galifianakis, Danny Boyle | Kid Cudi |
| Negative Puppy Ad, Late Night Hashtags - #voteforme, Jacob's Patience ||||
| 339 | November 4, 2010 (2010-11-04) | Dr. Phil McGraw, Nina Dobrev | Duffy |
| Remix The Clips, Battle Of The Instant Dance Crew, Microsoft Xbox Kinect Demo ||||
| 340 | November 5, 2010 (2010-11-05) | Elvis Costello, Lewis Black | Elvis Costello |
| Thank You Notes, Buzzwords ||||
| 341 | November 8, 2010 (2010-11-08) | Scarlett Johansson, Chris Morris | Toots & the Maytals |
| Suckers - Episode 1, Musical Instrument Game - Fallon Vs. Johansson ||||
| 342 | November 9, 2010 (2010-11-09) | Rosario Dawson, Ty Burrell | Rory Scovel |
| Pros & Cons - George W. Bush's Memoir, Do Not Read List, Total Iceholes - Fallon Vs. Dawson ||||
| 343 | November 10, 2010 (2010-11-10) | Rainn Wilson, Biz Stone, Evan Williams, Carla Gugino | Jónsi |
| Late Night Hashtags - #awwhellno, Charmed Scene Revisited ||||
| 344 | November 11, 2010 (2010-11-11) | Jeff Goldblum, Mark Valley | Robyn |
| Remix The Clips, Cell Phone Shootout ||||
| 345 | November 12, 2010 (2010-11-12) | Tracy Morgan, Dick Cavett | Kings of Leon |
| Slappington Manor, Thank You Notes, Won't You Pop My Balloon ||||
| 346 | November 15, 2010 (2010-11-15) | Daniel Radcliffe, Quincy Jones | Grinderman |
| Video Vision - Preparing Thanksgiving, Name That Guy ||||
| 347 | November 16, 2010 (2010-11-16) | Bruce Springsteen | N/A |
| Pros & Cons - Bruce Springsteen's Darkness on the Edge of Town, Neil Young - "Whip My Hair" by Willow ||||
| 348 | November 17, 2010 (2010-11-17) | Amanda Peet, Peter Krause | Rascal Flatts |
| Late Night Hashtags - #slapyourself, Harry Potter Super Fan Contest ||||
| 349 | November 18, 2010 (2010-11-18) | Anne Hathaway, Zachary Levi, Frank Shamrock | The Frames |
| Remix The Clips, Copy Machine Match Game ||||
| 350 | November 19, 2010 (2010-11-19) | Jake Gyllenhaal, Scott Caan, Kelli Giddish | Sufjan Stevens |
| Thank You Notes, Banana Boyz & Jake Gyllenhaal - Sarah Palin Reality Show ||||
| 351 | November 22, 2010 (2010-11-22) | David Hyde Pierce, Jimmie Johnson, Bobby Flay | Freddie Jackson |
| He Said She Said, Karate Pinata, Big Wheel Grand Prix ||||
| 352 | November 23, 2010 (2010-11-23) | Jessica Simpson, Chris Christie | Regina Spektor |
| Pros & Cons - Holiday Travel, Audience Suggestion Box, Tic-Tac-Toe - Fallon Vs. Simpson ||||
| 353 | November 24, 2010 (2010-11-24) | Colin Firth, Fran Lebowitz | N.E.R.D |
| Late Night Hashtags - #myfamilyisweird, Letters Home ||||
| 354 | November 25, 2010 (2010-11-25) | Bill Hader, Victoria Justice | James Otto, Ronnie Milsap |
| Thank You Notes, Freestyling With The Roots ||||

### December

| No. | Original air date | Guest(s) | Musical/entertainment guest(s) |
| 355 | December 6, 2010 (2010-12-06) | Martha Stewart, Gary Dell'Abate | R. Kelly |
| Reflections With Justin Bieber, Models & Buckets ||||
| 356 | December 7, 2010 (2010-12-07) | Michael C. Hall, Busy Philipps | R. Kelly |
| Pros & Cons - Being A Mall Santa, Competitive Spit-Takes ||||
| 357 | December 8, 2010 (2010-12-08) | Amy Adams, Mike Sorrentino | Adam Ferrara |
| 12 Days Of Christmas Sweaters Day 12, Late Night Hashtags - #keepyourpantson ||||
| 358 | December 9, 2010 (2010-12-09) | Paul McCartney, Nick Cannon | N/A |
| 12 Days Of Christmas Sweaters Day 11 ||||
| 359 | December 10, 2010 (2010-12-10) | Kirsten Dunst, Dee Snider | Maroon 5 |
| 12 Days Of Christmas Sweaters Day 10, Thank You Notes ||||
| 360 | December 13, 2010 (2010-12-13) | Jessica Alba, Colin Quinn | Stephen Bishop |
| 12 Days Of Christmas Sweaters Day 9, Battle Of The Instant Dance Crews, PS3 Uncharted Demo ||||
| 361 | December 14, 2010 (2010-12-14) | Bette Midler, Mario Batali, Rula Jebreal | Pegi Young |
| 12 Days Of Christmas Sweaters Day 8, Pros & Cons - Office Holiday Parties, John Bainer Press Conference ||||
| 362 | December 15, 2010 (2010-12-15) | Ben Stiller, Mike Mizanin | Annie Lennox |
| Slow Jam The News, 12 Days Of Christmas Sweaters Day 7, Charades - Fallon & Ben Stiller Vs. Anne Meara & Jerry Stiller ||||
| 363 | December 16, 2010 (2010-12-16) | Paul Rudd, Jon Lovitz | Aloe Blacc |
| 12 Days Of Christmas Sweaters Day 6, Late Night & Late Late Show Gift Exchange, Drunk On Christmas Song ||||
| 364 | December 17, 2010 (2010-12-17) | Jeff Bridges, Blythe Danner | Robert Plant & Band of Joy |
| 12 Days Of Christmas Sweaters Day 5, Thank You Notes, Cellphone Shootout ||||
| 365 | December 20, 2010 (2010-12-20) | Jason Segel, Hailee Steinfeld, Joshua Topolsky | Dr. Elmo |
| 12 Days Of Christmas Sweaters Day 4, Robert Is Bothered, Rockapella ||||
| 305F5F | December 21, 2010 (2010-12-21) | Jack Black, Stephen Dorff | The Roots |
| 12 Days Of Christmas Sweaters Day 3, Late Night Hashtags - #hohohellno, Jack Black singing "Holy Diver", Little Drummer Boy ||||
| 367 | December 22, 2010 (2010-12-22) | Ethan Hawke, Gillian Jacobs | José Feliciano |
| Head Swap, 12 Days Of Christmas Sweaters Day 2, Topical Carolers ||||
| 368 | December 23, 2010 (2010-12-23) | James Earl Jones, Dave Attell | Aaron Neville |
| 12 Days Of Christmas Sweaters Day 1, Remix the Clips ||||