# 2021 Challenger La Manche – Singles

Roman Safiullin was the defending champion but chose not to defend his title.
Ruben Bemelmans won the title after defeating Lukáš Rosol 6–4, 6–4 in the final.

## Seeds

* Denis Kudla (second round)
* Antoine Hoang (second round)
* Arthur Rinderknech (semifinals)
* Jurij Rodionov (second round)
* Peter Gojowczyk (second round)
* Bernabé Zapata Miralles (first round)
* Brandon Nakashima (withdrew)
* Sebastian Ofner (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| | Ruben Bemelmans | 6 | 3 | 7 | | | |
| 3 | Arthur Rinderknech | 3 | 6 | 5 | | | |
| 3 | Arthur Rinderknech | 3 | 6 | 5 | Ruben Bemelmans | 6 | 6 |
| | | | | | Lukáš Rosol | 4 | 4 |
| | Hugo Gaston | 5 | 6 | 3 | Lukáš Rosol | 4 | 4 |
| | Lukáš Rosol | 7 | 2 | 6 | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | D Kudla | 6 | 6 | | | | | | | | | | | | | | | | |
| Alt | N Serdarušić | 3 | 1 | | 1 | D Kudla | 1 | 7$^7$ | 3 | | | | | | | | | | |
| Q | M Geerts | 6$^2$ | 6 | 6 | Q | M Geerts | 6 | 6$^5$ | 6 | | | | | | | | | | |
| Q | J Forejtek | 7$^7$ | 4 | 2 | | | | | | Q | M Geerts | 6 | 1 | 6$^4$ | | | | | |
| | R Bemelmans | 3 | 6 | 6 | | | | | | | R Bemelmans | 4 | 6 | 7$^7$ | | | | | |
| LL | C Denolly | 6 | 1 | 4 | | R Bemelmans | 6 | 7$^7$ | | | | | | | | | | | |
| | D Istomin | 6 | 5 | 6 | | D Istomin | 4 | 6$^4$ | | | | | | | | | | | |
| Q | N Lammons | 3 | 7 | 4 | | | | | | | | | | | | R Bemelmans | 6 | 3 | 7 |
| 3 | A Rinderknech | 4 | 6 | 6 | | | | | | | | | | | 3 | A Rinderknech | 3 | 6 | 5 |
| | A Vatutin | 6 | 0 | 3 | 3 | A Rinderknech | 7$^7$ | 6 | | | | | | | | | | | |
| | I Sijsling | 2 | 4 | | WC | E Furness | 6$^5$ | 3 | | | | | | | | | | | |
| WC | E Furness | 6 | 6 | | | | | | | 3 | A Rinderknech | 7$^7$ | 7$^7$ | | | | | | |
| | C Lestienne | 1 | 6 | 6 | | | | | | | C Lestienne | 6$^4$ | 6$^3$ | | | | | | |
| Q | T Droguet | 6 | 1 | 2 | | C Lestienne | 6 | 6 | | | | | | | | | | | |
| WC | M Martineau | 7$^{14}$ | 6 | | WC | M Martineau | 3 | 4 | | | | | | | | | | | |
| 6 | B Zapata Miralles | 6$^{12}$ | 3 | | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5 | P Gojowczyk | 6 | 6 | | | | | | | | | | | | | | | |
| | T-l Wu | 2 | 4 | | 5 | P Gojowczyk | 6 | 3 | 2 | | | | | | | | | |
| | J Lenz | 1 | 6 | 3 | | H Gaston | 4 | 6 | 6 | | | | | | | | | |
| | H Gaston | 6 | 3 | 6 | | | | | | | H Gaston | 6 | 6 | | | | | |
| | G Oliveira | 1 | 4 | | | | | | | Alt | L Klein | 0 | 3 | | | | | |
| Alt | L Klein | 6 | 6 | | Alt | L Klein | 4 | 6 | 6 | | | | | | | | | |
| WC | K de Schepper | 5 | 6 | 3 | 4 | J Rodionov | 6 | 1 | 3 | | | | | | | | | |
| 4 | J Rodionov | 7 | 3 | 6 | | | | | | | | | | | H Gaston | 5 | 6 | 3 |
| 8 | S Ofner | 6 | 6 | | | | | | | | | | | | L Rosol | 7 | 2 | 6 |
| | Y Maden | 1 | 3 | | 8 | S Ofner | 3 | 2 | | | | | | | | | | |
| | M Janvier | 6$^4$ | 0$^r$ | | | K Żuk | 6 | 6 | | | | | | | | | | |
| | K Żuk | 7$^7$ | 1 | | | | | | | | K Żuk | 6$^2$ | 6 | 6$^2$ | | | | |
| | L Rosol | 1 | 6 | 7$^8$ | | | | | | | L Rosol | 7$^7$ | 4 | 7$^7$ | | | | |
| Alt | A Molčan | 6 | 3 | 6$^6$ | | L Rosol | 6 | 5 | 7 | | | | | | | | | |
| | M Trungelliti | 1 | 0 | | 2 | A Hoang | 3 | 7 | 5 | | | | | | | | | |
| 2 | A Hoang | 6 | 6 | | | | | | | | | | | | | | | |