# 2022 Internazionali di Tennis Città di Trieste – Singles

Tomás Martín Etcheverry was the defending champion but chose not to defend his title.
Francesco Passaro won the title after defeating Zhang Zhizhen 4–6, 6–3, 6–3 in the final.

## Seeds

* Norbert Gombos (quarterfinals)
* Franco Agamenone (quarterfinals)
* Gianluca Mager (first round)
* Dennis Novak (first round)
* Marco Cecchinato (second round)
* Nikola Milojević (first round)
* Santiago Rodríguez Taverna (second round)
* Alexandre Müller (semifinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| | Francesco Passaro | 6 | 6 | | | | | |
| SE | Francesco Maestrelli | 1 | 2 | | | | | |
| SE | Francesco Maestrelli | 1 | 2 | | Francesco Passaro | 4 | 6 | 6 |
| | | | | Q | Zhang Zhizhen | 6 | 3 | 3 |
| Q | Zhang Zhizhen | 6 | 6 | Q | Zhang Zhizhen | 6 | 3 | 3 |
| 8 | Alexandre Müller | 3 | 2 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | N Gombos | 6 | 6 | | | | | | | | | | | | | | | |
| | F Gaio | 2 | 1 | | 1 | N Gombos | 6 | 6 | | | | | | | | | | |
| | A Collarini | 4 | 6 | 6 | | A Collarini | 3 | 2 | | | | | | | | | | |
| Alt | L Darderi | 6 | 1 | 3 | | | | | | 1 | N Gombos | 3 | 6 | 2 | | | | |
| | A Seppi | 2 | 0 | | | | | | | | F Passaro | 6 | 3 | 6 | | | | |
| WC | M Bellucci | 6 | 6 | | WC | M Bellucci | 6$^2$ | 1 | | | | | | | | | | |
| | F Passaro | 7 | 6 | | | F Passaro | 7$^7$ | 6 | | | | | | | | | | |
| 6 | N Milojević | 5 | 1 | | | | | | | | | | | | | F Passaro | 6 | 6 |
| 3 | G Mager | 3 | 0 | | | | | | | | | | | | SE | F Maestrelli | 1 | 2 |
| Alt | N Fatić | 6 | 6 | | Alt | N Fatić | 3 | 6 | 3 | | | | | | | | | |
| Q | G Oradini | 3 | 4 | | | S Caruso | 6 | 2 | 6 | | | | | | | | | |
| | S Caruso | 6 | 6 | | | | | | | | S Caruso | 3 | 3 | | | | | |
| SE | F Maestrelli | 6 | 6 | | | | | | | SE | F Maestrelli | 6 | 6 | | | | | |
| Q | Andrey Chepelev | 2 | 3 | | SE | F Maestrelli | 7 | 7$^7$ | | | | | | | | | | |
| Q | E Gulbis | 4 | 6$^2$ | | 7 | S Rodríguez Taverna | 5 | 6$^2$ | | | | | | | | | | |
| 7 | S Rodríguez Taverna | 6 | 7$^7$ | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5/WC | M Cecchinato | 1 | 6 | 7 | | | | | | | | | | | | | | |
| | A Martin | 6 | 4 | 5 | 5/WC | M Cecchinato | 3 | 2 | | | | | | | | | | |
| | M Pucinelli de Almeida | 3 | 2 | | Q | Zh Zhang | 6 | 6 | | | | | | | | | | |
| Q | Zh Zhang | 6 | 6 | | | | | | | Q | Zh Zhang | 2 | 6 | 6 | | | | |
| | G Blancaneaux | 6 | 7$^7$ | | | | | | | | F Meligeni Alves | 6 | 3 | 3 | | | | |
| | G Simon | 3 | 6$^4$ | | | G Blancaneaux | 7$^8$ | 2 | 6$^3$ | | | | | | | | | |
| | F Meligeni Alves | 2 | 7 | 6 | | F Meligeni Alves | 6$^6$ | 6 | 7$^7$ | | | | | | | | | |
| 4 | D Novak | 6 | 5 | 4 | | | | | | | | | | | Q | Zh Zhang | 6 | 6 |
| 8 | A Müller | 5 | 6 | 6 | | | | | | | | | | | 8 | A Müller | 3 | 2 |
| | A Pellegrino | 7 | 3 | 2 | 8 | A Müller | 7 | 6 | | | | | | | | | | |
| WC | M Gigante | 6 | 3 | 4 | Q | L Neumayer | 5 | 0 | | | | | | | | | | |
| Q | L Neumayer | 1 | 6 | 6 | | | | | | 8 | A Müller | 6 | 6$^4$ | 6 | | | | |
| Q | Samuel Vincent Ruggeri | 2 | 4 | | | | | | | 2 | F Agamenone | 0 | 7$^7$ | 2 | | | | |
| | R Olivo | 6 | 6 | | | R Olivo | 6 | 5 | 1 | | | | | | | | | |
| | A Arnaboldi | 4 | 3$^r$ | | 2 | F Agamenone | 1 | 7 | 6 | | | | | | | | | |
| 2 | F Agamenone | 6 | 2 | | | | | | | | | | | | | | | |