OpenLLM-France/wikimedia huggingface dataset:
# 2',3'-Cyclic-nucleotide 3'-phosphodiesterase

2′,3′-Cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37, CNPase, systematic name nucleoside-2′,3′-cyclic-phosphate 2′-nucleotidohydrolase) is an enzyme that in humans is encoded by the CNP gene.

## Reaction

CNPase catalyzes the following reaction:
    nucleoside 2′,3′-cyclic phosphate + H$_2$O $\rightleftharpoons$ nucleoside 2′-phosphate

## Function

CNPase is a myelin-associated enzyme that makes up 4% of total CNS myelin protein, and is thought to undergo significant age-associated changes. It is named for its ability to catalyze the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides, though a cohesive understanding of its specific physiologic functions are still ambiguous.
Structural studies have revealed that four classes of CNPases belong to one protein superfamily. CNPase's catalytic core consists of three alpha-helices and nine beta-strands. The proposed mechanism of CNPases phosphodiesterase catalytic activity is similar to the second step of the reaction mechanism for RNase A.
CNPase is expressed exclusively by oligodendrocytes in the CNS, and the appearance of CNPase seems to be one of the earliest events of oligodendrocyte differentiation. CNPase is thought to play a critical role in the events leading up to myelination.
CNPase also associates with microtubules in brain tissue and FRTL-5 thyroid cells, and is reported to have microtubule-associated protein-like activity (MAP; see MAP2), being able to catalyze microtubule formation at low molar ratios. Deletion of the C-terminus of CNPase or phosphorylation abolish the catalytic activity of microtubule formation. CNPase can link tubulin to cellular membranes, and might be involved in the regulation cytoplasmic microtubule distribution.
CNPase has also been demonstrated to inhibit the replication of HIV-1 and other primate lentiviruses by binding the retroviral Gag protein and inhibiting the genesis of nascent viral particles. Whether this is a biological function of CNPase or a coincidental activity remains unclear.
# 1964 NC State Wolfpack football team

The 1964 NC State Wolfpack football team represented North Carolina State University during the 1964 NCAA University Division football season. The Wolfpack were led by 11th-year head coach Earle Edwards and played their home games at Riddick Stadium in Raleigh, North Carolina. They competed as a member of the Atlantic Coast Conference, finishing as conference champions with a record of 5–2.

## Schedule

| Date | Opponent | Site | Result | Attendance |
| September 19 | at North Carolina | Kenan Memorial StadiumChapel Hill, NC (rivalry) | W 14–13 | 45,500 |
| September 26 | Clemson | Riddick StadiumRaleigh, NC (rivalry) | W 9–0 | 17,500 |
| October 3 | Maryland | Riddick StadiumRaleigh, NC | W 14–13 | 14,500 |
| October 10 | at No. 3 Alabama* | Denny StadiumTuscaloosa, AL | L 0–21 | 37,827 |
| October 17 | at Duke | Duke StadiumDurham, NC (rivalry) | L 3–35 | 34,000 |
| October 24 | at Virginia | Scott StadiumCharlottesville, VA | W 24–15 | 20,100 |
| October 31 | South Carolina | Riddick StadiumRaleigh, NC | W 17–14 | 21,000 |
| November 7 | at Virginia Tech* | Miles StadiumBlacksburg, VA | L 19–28 | 11,500 |
| November 14 | at Florida State* | Doak Campbell StadiumTallahassee, FL | L 6–28 | 24,250 |
| November 20 | at Wake Forest | Bowman Gray StadiumWinston-Salem, NC (rivalry) | L 13–27 | 17,300 |
| *Non-conference gameRankings from AP Poll released prior to the game ||||||
# Wilhelms

Wilhelms is a surname. Notable people with the surname include:
* Carl Wilhelms [fi] (1889–1953), Finnish artist
* Don Wilhelms (born 1930), American geologist, namesake of minor planet 4826 Wilhelms
* Einar Wilhelms (1895–1978), Norwegian footballer
* Eino Wilhelms [fi] (1918–2010), Finnish theologian
* Gary Wilhelms (born 1938), American politician
* Jane Wilhelms (died 2005), American biologist and computer scientist
* Jenny Wilhelms (born 1974), Finnish musician
* Manfred Wilhelms [de], German cinematographer
* Ralf Wilhelms (born 1962), German footballer
* Thorsten Wilhelms (born 1969), German cyclist
# Botsford Inn

The Botsford Inn is a nineteenth century inn and tavern located at 28000 Grand River Avenue in Farmington, Michigan. It was listed on the National Register of Historic Places in 1979.

## History

In 1836, Orrin Weston, a farmer, constructed the original portion of this inn as his personal residence. In 1841, Stephen Jennings purchased the house and converted it into a tavern. The building served as a stagecoach stop on what was then the Grand River Plank Road, connecting Detroit to Lansing and Grand Rapids. Jennings likely enlarged the house at this time, adding a rear ell and two bays onto the previously extant structure. In 1860, Milton C. Botsford purchased the inn, renaming it the Botsford Tavern. The Tavern served as a popular meeting place for farmers, drovers, local residents and travelers.
The Botsford family owned the inn until the 1920s. At that time, Grand River Avenue was being widened to create U.S. Route 16, and the inn was in danger of being razed. However, in 1924, Henry Ford purchased the Inn from the Botsford family and moved it back from its original site out of the way of the road widening project. Ford had attended gatherings at the inn when he was younger, and had courted his wife Clara there. Ford rehabilitated the structure, enlarging the ell and installing period woodwork.
The Ford family continued to operate the Botsford Inn as a restaurant until 1951, when it was purchased by John Anhut. Anhut preserved the interior of the old inn much as the Fords left it, but the popularity of the inn led him to construct several new wings after 1960. While Anhut was owner the Botsford Inn was presented with a painting by Michigan-based folk artist Grace McArthur.
In the mid-1960, a development group purchased much of the property associated with the Inn, constructing Botsford Hospital and House of Botsford Apartments. However, by the 1990s, economic pressures made it difficult to keep the inn open. In 1993, the Anhut family sold the Inn to Creon Smith. By 2000, the inn had closed. In 2007, Botsford Hospital razed the 1960 wings of the Inn to make room for a new cancer center. The hospital restored the historic portions of the building, and the Inn is now part of the Botsford Hospital complex.

## Description

The Botsford Inn is a two-story, seven-bay, flank-gable-roofed, clapboarded structure with a two-story porch across the front. A long, six-bay ell extends to the rear on one side. The original 1836 building consists of the encompasses the five bays on the left-hand side, between the chimneys. The rightmost two bays were likely added in about 1841, at the same time that the front porch was constructed. An elaborate Federal style doorway with sidelights opens on the first story, with a less elaborate doorway directly above.
The interior has much of the original simple trim, including horizontal board wainscoting, plain millwork window and door casings, and several Federal style mantels as well as some wide-board floors. During the 1924 renovation, some excellent reproduction woodwork was installed.
# St. Peter's Church, Laragh

St. Peter's Church in Laragh, County Monaghan, Ireland, is a tin tabernacle constructed in 1890 from corrugated iron and timber.

## History

The Swiss-Gothic design of the church was inspired by travels on the continent in the 1800s by Laragh Tweed Mill operator James McKean and his wife.
Local rumour suggests McKean had the mill river realigned to create the spectacular site in Aughnamullen parish, the intention being to build a Catholic church to serve the mill workers of the town. However, following a breakdown in industrial relations, a falling out with the local clergy and the eventual permanent closure of the Irish Laragh Tweed factory in 1885, St. Peter's was eventually built in 1890 and consecrated as Church of Ireland on 13 August 1891.
St. Peter's was de-consecrated in 1962.

## Restoration

In 2012, Laragh Heritage group was formed to raise funds to restore St. Peter's back to its former glory.
On 13 September 2014, St. Peter's Church was officially reopened.
* An interior view of the altar and stained glass window
# Torynorrhina hyacinthina

Torynorrhina hyacinthina is a beetle of the family Scarabaeidae and subfamily Cetoniinae.

## Distribution

This flower beetle can be found from India to Thailand.
# Wilkiea kaarruana

Wilkiea kaarruana is a species of flowering plant in the family Monimiaceae, and is endemic to northern Queensland. It is a shrub or small tree with elliptic to oblong leaves, and male and female flowers on separate plants, each with 4 to 6 tepals. Male flowers usually have 2 pairs of stamens and female flowers have about 21 to 26 carpels.

## Description

Wilkiea kaarruana is a shrub or small tree that typically grows to a height of 5–12 m (16–39 ft) and has thick, corky, fissured bark. Its leaves are elliptic to oblong, 60–150 mm (2.4–5.9 in) long and 25–60 mm (0.98–2.36 in) wide on a petiole 5–12 mm (0.20–0.47 in) long. The leaves are glabrous and slaty-green on the upper surface. Male and female flowers are borne on separate plants with 4 to 6 tepals. Male flowers are borne in clusters of up to 15, 10–40 mm (0.39–1.57 in) long in leaf axils, on the ends of branches or on the sides of woody branches, each flower more or less spherical 2.0–3.5 mm (0.079–0.138 in) long on a pedicel 5–18 mm (0.20–0.71 in) long with 2 pairs of stamens. Female flowers are borne on the ends of branchlets in groups of 6 to 14, 30–50 mm (1.2–2.0 in) long, each flower more or less spherical, about 7 mm (0.28 in) in diameter, on a pedicel 11–24 mm (0.43–0.94 in) long, with 20 to 26 carpels. Flowering has been observed in October and November, but mature fruit have not been observed.

## Taxonomy

Wilkiea kaarruana was first formally described in 2011 by Frank Zich and Andrew James Ford, from specimens collected by Ford in the Wooroonooran National Park in 2007. The specific epithet (kaarruana) refers to Kaarru (pronounced "Kaa-roo") Creek, where several plants, and the first female examples, were found.

## Distribution and habitat

This species grows in mountainous rainforest in the Ngalba Bulal National Park, the headwaters of the Daintree River, on Mount Bartle Frere and in the catchment of the South Johnstone River in far north Queensland.
# Twardowski

Twardowski (feminine: Twardowska, plural: Twardowscy) is a Polish surname. Tvardovsky, feminine: Tvardovskaya, are English transliterations from Russian. Notable people with the surname include:
* Jan Twardowski (1915–2006), Polish priest and poet
* Julia Twardowska (born 1995), Polish female volleyball player
* Kasper Twardowski, (1592-ca. 1641), Polish poet
* Kazimierz Twardowski (1866–1938), Polish philosopher and logician
* Romuald Twardowski (1930–2024), Polish composer
* Aleksandr Tvardovsky (1910–1971), Russian poet

## Fictional characters

* Pan Twardowski, a fictional character from Polish folklore and literature, who sold his soul in exchange for special powers
* Pani Twardowska from the humorous ballad by Adam Mickiewicz
# 1967 Irish Greyhound Derby

The 1967 Irish Greyhound Derby took place during July and August with the final being held at Harold's Cross Stadium in Dublin on 4 August 1967.
The winner Russian Gun won £2,000 and was trained by Tom Lynch, owned by Hugh Marley and bred by Frank Muldoon.

## Final result

At Harold's Cross, 4 August (over 525 yards):
| Position | Winner | Breeding | Trap | SP | Time | Trainer |
| 1st | Russian Gun | Pigalle Wonder - Shandaroba | 3 | 5-1 | 29.44 | Tom Lynch |
| 2nd | Dry Flash | Prairie Flash - Newhill Snowdrop | 6 | 3-1 | 29.68 | |
| 3rd | Hurricane Bertie | Prairie Flash - unknown | 2 | 10-1 | 29.84 | |
| 4th | Ricard Flash | Prairie Flash - unknown | 1 | 11-4f | | |
| 5th | Proud Lincoln | Clonalvy Pride - Gettysburgh Princess | 4 | 7-2 | | Ger McKenna |
| 6th | Baled Hay | Prairie Flash - unknown | 5 | 5-1 | 00.00 | |

### Distances

3, 2 (lengths)

## Competition Report

Legendary Irish trainer Tom Lynch was ill in hospital when he received a telephone call from a Portadown building contractor called Hugh Marley. Marley had seen his black dog Russian Gun eliminated from the 1967 English Greyhound Derby at the qualifying round stage but persuaded Lynch to train him for a tilt at the Irish Derby. Marley had paid breeder Frank Muldoon £3,000 for greyhound.
During the first round Yanka Boy recorded 29.31, Public Reply (the McAlinden Cup winner) won in 29.32; other winners were Ricard Flash 29.37, Proud Lincoln 29.44, Whiteleas Gift (Produce Stake winner) 29.61 and Sutton Valley 29.64.
In round two Whiteleas Gift impressed after setting a very fast time of 29.20 and both Mount Mick and Hack It Buffalo went very well recording 29.24 and 29.37 respectively. Yanka Boy won again and Dry Flash beat Russian Gun, the latter still yet to win a heat.
Before the semi-finals Yanka Boy and Whiteleas Gift were the new competition favourites but the round proved pivotal as the major names crashed out, the first semi saw Hurricane Bertie defeat Dry Flash with Yanka Boy managing just third place. Baled Hay beat Ricard Flash in the second heat before Proud Lincoln won the third from Russian Gun with Whiteleas Gift failing to make the final.
When the traps rose for the final Russian Gun (normally a slow starter) bolted from the traps and that was that, the crowd knew there would be no catching him and he duly wrapped up an easy victory in 29.44. Dry Flash ran well for second place with the strong finishing Hurricane Bertie taking third place. It was to be the last Derby ever held at Harold's Cross.
# Yargo Department

Yargo is a department or commune of Kouritenga Province in eastern Burkina Faso. Its capital lies at the town of Yargo. According to the 1996 census the department has a total population of 14,473.

## Towns and villages

* Yargo (1 014 inhabitants) (capital)
* Balbzinko (783 inhabitants)
* Balgo (1 680 inhabitants)
* Bissiga (647 inhabitants)
* Bissiga-Peulh (29 inhabitants)
* Daltenga (991 inhabitants)
* Kamsansin (362 inhabitants)
* Kanougou (646 inhabitants)
* Kokossé Tandaga (883 inhabitants)
* Kokossin Nabikome (898 inhabitants)
* Lilyala (575 inhabitants)
* Pissi-Sebgo (965 inhabitants)
* Poétenga (1 216 inhabitants)
* Sawadogo (373 inhabitants)
* Silmaiougou-Boumdoundi (1 110 inhabitants)
* Silmiougou-Peulh (202 inhabitants)
* Silmiougou-Yarcé (850 inhabitants)
* Tandadtenga (506 inhabitants)
* Zanrin (740 inhabitants)
# CEAM Modèle 1950

The CEAM Modèle 1950 was a prototype assault rifle chambered in the .30 Carbine round. It was developed by Centre d'Etudes et d'Armement de Mulhouse (CEAM) of France during the late 1940s/early 1950s, as a development of the German StG 45(M) assault rifle. The three initial prototypes, designated Modèle 1, were chambered in 7.92×33mm Kurz, 7.65×35mm (an experimental French cartridges developed by Cartoucherie de Valence), and .30 Carbine. All succeeding prototypes (Modèle 1949, Modèle II, and the definitive Modèle 1950) were chambered in .30 Carbine. All versions of the design included a combined bipod/handguard and a folding buttstock. Due to economic considerations, with France fighting the Indochina War and being the second biggest NATO contributor, the weapon was cancelled. Co-designer Ludwig Vorgrimler then left for Spain, where he further developed the concept into the CETME rifle, which in turn was developed into the Heckler & Koch G3.
# Bourcia

Bourcia (French pronunciation:) is a former commune in the Jura department in Bourgogne-Franche-Comté in eastern France. On 1 January 2017, it was merged into the new commune Val Suran.
# St Julitta's Church, Lanteglos-by-Camelford

St Julitta's Church, Lanteglos-by-Camelford is a Grade I listed parish church in the Church of England Diocese of Truro in Lanteglos-by-Camelford, Cornwall. (St Julitta's Church, St Juliot, is dedicated to the same local saint.)

## History

The church dates from the 12th century, with a 14th-century tower. The six bay south aisle and possibly also the south porch were added in the 15th century.
In 1860 the church was re-roofed.
It was restored in a heavy-handed manner by James Piers St Aubyn starting in 1865. Restoration of the nave and south aisle by Messrs Westlake and Cann were completed by August 1867 such that the church could be reopened but further work was still ongoing.
Further restoration was done in 1873.
In 1870, one of the choristers, George Perry, aged 12, an inmate of the workhouse, was detected stealing half a crown (equivalent to £15.11 in 2023) from the offertory whilst “bearing the bag” in the church. He was remanded for a month.

## Parish status

The church is in a joint benefice with:
* St Adwen's Church, Advent
* St Thomas of Canterbury's Church, Camelford

## Memorials

* W. Inch (d. 1815) by Robert Isbell of Stonehouse

## Organ

The organ dated from around 1793 and was built by William Allen of London. A specification of the organ can be found in the National Pipe Organ Register. It was removed in 1986.

## Bells

The tower contains a peal of 6 bells. Four date from 1783 and are by John II Pennington and Christopher IV Pennington. The remaining two are from 1883 by John Warner & Sons.

## Churchyard crosses

The church is noted for the four medieval wheel-headed crosses and an inscribed stone from the 10th century which reads AELSELD 7 GENERED WOHTE YSNE SYBSTEL FOR AELWYNEYS SOUL 7 FOR HEYSEL. This has been translated as Aelsel and Genere made this family stone or place of peace for Aelwine's soul and for themselves or Heysel. Discovered at Castle Goff Farm in 1858, it was relocated here in 1900 and is now a scheduled monument. The Anglo-Saxon inscription is hard to read: another version is "Aelselth ⁊ Genereth wohte thisne sybstel for Aelwines soul ⁊ for heysel" (Alseth and Generth wrought this personal memorial for Aelwine and for themselves).
# Tic&Tac

Professional ratings :
| Review scores ||
| Source | Rating |
| Allmusic | (?) |
Tic&Tac is the eighth album of the jazz fusion band Area and was released in 1980. It is the first album without Demetrio Stratos as he died a year earlier, and it is generally more jazzy than progressive. This is the only album in which Larry Nocella [it] performs. After releasing this, Area toured until 1983, then disbanded. Giulio Capiozzo [it] in 1986 formed a jazz fusion band called Area II, but was the only original member. Area reformed officially in 1993 with a concert in Rome, as a trio, with Ares Tavolazzi, Patrizio Fariselli [it] and Capiozzo. However, they didn't record anything new in studio until 1997 when the album "Chernobyl 7991" was released (without Tavolazzi). This album is completely instrumental, save for the final track "Antes de Hablar Abra la Boca".

## Track listing
### Side one

* "La Torre Dell'Alchimista" (Fariselli) – 5:50
* "Danza ad Anello" (Fariselli) – 5:13
* "A.S.A." (Fariselli) – 4:34
* "Lectric Rag" (Fariselli) – 1:50
* "La Luna Nel Pozzo" (Fariselli) – 3:41

### Side two

* "Tic & Tac" (Fariselli) – 4:38
* "Quartet" (Tavolazzi) – 2:12
* "Sibarotega" (Fariselli) – 4:16
* "Chantee D'Amour" (Tavolazzi) – 4:47
* "Antes de Hablar Abra la Boca" (Fariselli) – 4:22

## Personnel

* Patrizio Fariselli – acoustic and electric piano, synthesizers
* Larry Nocella – tenor sax
* Giulio Capiozzo – drums
* Ares Tavolazzi – electric bass, double bass, guitar

### Guest musicians

* Guido Guidoboni – trumpet in "Danza ad anello" and "Sibarotega"
* Luciano Biasutti – trumpet in "Antes de Hablar Abra la Boca"
* Pino Vicari – voice in "Antes de Hablar Abra la Boca"
# Wayne E. Whitlatch

Wayne E. Whitlatch (9 October 1928 – 26 October 2017) was a retired major general in the United States Air Force who served as commander of the Air Force Test and Evaluation Center from 1980 to 1982.
# Twardzik

Twardzik is a surname. Notable people with the surname include:
* Dan Twardzik (born 1991), Czech footballer
* Dave Twardzik (born 1950), American basketball player
* Dick Twardzik (1931–1955), American jazz pianist
* Filip Twardzik (born 1993), Czech footballer
* Patrik Twardzik (born 1993), Czech footballer
* René Twardzik (born 1970), Czech footballer
* Ted Twardzik, Mrs. T's Pierogies founder
# 2,3-Dihydroxycinnamic acid

2,3-Dihydroxycinnamic acid is a hydroxycinnamic acid. It is an isomer of caffeic acid.
It is a metabolite found in human urine.
# Yargo (novel)

Yargo is a romantic science fiction novel by Jacqueline Susann. It was written during the 1950s, but not published until 1979, four years after Susann's death.

## Plot summary

Yargo tells the story of Janet Cooper, a young woman from Avalon, New Jersey, who is abducted by aliens from the planet Yargo. During her interplanetary adventures with these intelligent but emotionless extraterrestrials, she falls in love with their leader.

## Background

Jacqueline Susann had long been interested in science fiction; her widower, Irving Mansfield, said that when they first met, she wanted to spend their dates at the Hayden Planetarium instead of at nightclubs. In the early 1950s, she began to write Yargo, originally called The Stars Scream. She finished the book in 1956, and gave it to MCA agent George Chasin, who attempted to sell the story to Hollywood. Unsuccessful, he put the manuscript aside, where it was forgotten until Chasin reportedly was cleaning out a filing cabinet after Susann's death. Irving Mansfield suggested Chasin send it to Bantam Books, Susann's long-time paperback publisher; Bantam accepted it for publication, with a first printing of 1.3 million copies. The story also appeared in the February 1979 issue of the Ladies' Home Journal, which had enjoyed a huge success five years earlier when it published Susann's original novella, Dolores. Yargo was published on February 28, 1979.

## Reception

Critical notices were negative: one critic wrote, "It's awful, as usual, and it will sell, as usual." The Science Fiction & Fantasy Book Review stated that Yargo is "mildly entertaining," but "has no lasting value... except perhaps as a curiosity." Yargo was, nonetheless, a best seller, spending seven weeks on the New York Times Mass Market Paperback list. The blog The Sleaze Factor, that celebrates trashy books, movies and pop culture, found Yargo "Very delightful indeed." He continues, "Contrary to what some may believe, Yargo is surprisingly effective. Of course you have to dig Jacqueline Susann to really get this one. We’re not talking about [fantasy and science fiction author] Alan Dean Foster here. Yargo is just a quick and satisfying—and yes, silly—read that will make anyone on the Susann band wagon smile and appreciate her range as a trashy novelist."
# St Julian's Road

St Julian's Road is a former football stadium in Omagh, Northern Ireland. It was the home ground of Omagh Town until the dissolution of the club in June 2005. The ground, which featured a grass pitch, had a capacity of 5000, made up of thirty 30 VIP places, 250 covered seats, 4720 standing places (3220 covered and 1500 uncovered). In 2020 the former site of the ground was demolished after laying derelict since the clubs demise and renovated into St Julians Park.

## History

Town first leased the Mullaghmore site, which had previously served as a rubbish tip, from Omagh District Council in 1987, with the stadium opening three years later. As well as football the ground has also hosted Gaelic Athletic Association events.

## Charity matches

Among the clubs to play at St. Julian's Road were Manchester United, who faced Omagh Town in a friendly game there in 1999 in order to raise money for the Omagh bombing appeal. The match ended in a 9–0 win to the visitors with Teddy Sheringham netting four times. Both Chelsea and Liverpool also faced the home side at St Julian's Road as part of the same charity initiative.

## Current use

Following the collapse of the football club, the stadium fell into disuse although in January 2010, Sean Begley, a Sinn Féin councillor, brought a proposal before the council to revive St Julian's Road as a football venue. In 2020 the remains of the ground were demolished and renovated into a public park.