# Swimming at the 2022 European Aquatics Championships – Men's 4 × 100 metre medley relay

The Men's 4 × 100 metre medley relay competition of the 2022 European Aquatics Championships was held on 17 August 2022.

## Records

Prior to the competition, the existing world, European and championship records were as follows.
| | Team | Time | Location | Date |
| World record | United States | 3:26.78 | Tokyo | 1 August 2021 |
| European record | Great Britain | 3:27.51 | Tokyo | 1 August 2021 |
| European record | Italy | 3:27.51 | Budapest | 25 June 2022 |
| Championship record | Great Britain | 3:28.59 | Budapest | 23 May 2021 |
The following new records were set during this competition.
| Date | Event | Nation | Time | Record |
| 17 August | Final | Italy | 3:28.46 | CR |

## Results
### Heats

The heats were started at 10:11.
| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| 1 | 1 | 2 | Italy | Michele Lamberti (54.95) Federico Poggio (59.70) Federico Burdisso (51.37) Manuel Frigo (48.33) | 3:34.35 | Q |
| 2 | 2 | 5 | Austria | Bernhard Reitshammer (55.31) Valentin Bayer (59.43) Simon Bucher (51.85) Heiko Gigler (48.23) | 3:34.82 | Q |
| 3 | 2 | 2 | Great Britain | Jonathon Marshall (54.67) James Wilby (59.92) Jacob Peters (52.67) Jacob Whittle (48.19) | 3:35.45 | Q |
| 4 | 1 | 4 | France | Mewen Tomac (54.72) Antoine Viquerat (1:00.71) Clément Secchi (51.74) Charles Rihoux (48.29) | 3:35.46 | Q |
| 5 | 2 | 0 | Poland | Kacper Stokowski (54.09) Dawid Wiekiera (1:00.85) Adrian Jaśkiewicz (52.03) Kamil Sieradzki (49.07) | 3:36.04 | Q |
| 6 | 2 | 8 | Ukraine | Oleksandr Zheltyakov (55.10) Volodymyr Lisovets (1:00.36) Denys Kesil (52.49) Sergii Shevtsov (48.74) | 3:36.69 | Q |
| 7 | 2 | 3 | Germany | Ole Braunschweig (54.17) Lucas Matzerath (1:00.61) Björn Kammann (53.87) Peter Varjasi (48.30) | 3:36.95 | Q |
| 8 | 1 | 3 | Spain | Nicolás García (55.66) Carles Coll (1:01.45) Mario Mollà (52.09) Sergio de Celis (47.89) | 3:37.09 | Q |
| 9 | 1 | 7 | Bulgaria | Kaloyan Levterov (55.76) Tonislav Sabev (1:00.82) Antani Ivanov (52.78) Deniel Nankov (48.66) | 3:38.02 | |
| 10 | 1 | 1 | Greece | Theodoros Andreopoulos (55.12) Arkadios Aspougalis (1:02.16) Konstantinos Stamou (53.03) Stergios Bilas (49.04) | 3:39.35 | |
| 11 | 1 | 6 | Lithuania | Erikas Grigaitis (56.05) Andrius Šidlauskas (1:00.20) Danas Rapšys (53.94) Tomas Navikonis (50.01) | 3:40.20 | |
| 12 | 1 | 5 | Sweden | Björn Seeliger (56.59) Daniel Räisänen (1:01.55) Oskar Hoff (53.68) Robin Hanson (49.88) | 3:41.70 | |
| 13 | 2 | 4 | Luxembourg | Max Mannes (56.96) Pit Brandenburger (1:04.55) Julien Henx (55.11) Rémi Fabiani (49.72) | 3:46.34 | |
| | 1 | 8 | Norway | Markus Lie (55.53) Christoffer Haarsaker (1:01.62) Jon Jøntvedt Nicholas Lia | Disqualified | Disqualified |
| | 2 | 1 | Ireland | | Did not start | Did not start |
| | 2 | 6 | Netherlands | | Did not start | Did not start |
| | 2 | 7 | Switzerland | | Did not start | Did not start |

### Final

The final was held at 19:25.
| Rank | Lane | Nation | Swimmers | Time | Notes |
| | 4 | Italy | Thomas Ceccon (52.82) Nicolò Martinenghi (57.72) Matteo Rivolta (50.75) Alessandro Miressi (47.17) | 3:28.46 | CR |
| | 6 | France | Yohann Ndoye-Brouard (53.06) Antoine Viquerat (1:00.48) Clément Secchi (51.53) Maxime Grousset (47.43) | 3:32.50 | |
| | 5 | Austria | Bernhard Reitshammer (54.68) Valentin Bayer (59.54) Simon Bucher (50.97) Heiko Gigler (48.09) | 3:33.28 | |
| 4 | 3 | Great Britain | Luke Greenbank (54.28) James Wilby (59.51) Edward Mildred (51.72) Thomas Dean (48.09) | 3:33.60 | |
| 5 | 2 | Poland | Ksawery Masiuk (53.49) Dawid Wiekiera (1:00.79) Jakub Majerski (51.17) Karol Ostrowski (48.71) | 3:34.16 | |
| 6 | 7 | Ukraine | Oleksandr Zheltyakov (54.60) Volodymyr Lisovets (59.40) Denys Kesil (52.12) Sergii Shevtsov (48.54) | 3:34.66 | NR |
| 7 | 1 | Germany | Ole Braunschweig (54.40) Lucas Matzerath (59.74) Björn Kammann (53.60) Peter Varjasi (47.91) | 3:35.65 | |
| 8 | 8 | Spain | Nicolás García (55.30) Carles Coll (1:01.31) Mario Mollà (52.20) Sergio de Celis (48.44) | 3:37.25 | |