OpenLLM-France/wikimedia huggingface dataset:
# CVac

CVac (short for Cancer Vaccine), is an immunotherapeutic agent that was 1st developed in Australia.
CVac was developed by the biotechnology company Prima BioMed (Nasdaq: PBMD) through to Phase II clinical studies between 2001 and 2015. After inconclusive clinical data in ovarian cancer 2013 and 2014, Prima announced in February 2015 that it had ceased recruiting into CVAc clinical studies and was seeking commercial partners for the product.

## Treatment method

CVac is an ex vivo dendritic cell priming technology involving MFP, or mannan fusion protein, where a fusion protein of MUC1 and Glutathione S-transferase is coupled to oxidized polymannose. The dendritic cells are the orchestrators of the immune system. 'Priming' dendritic cells involves exposing those cells to disease antigens in order to get the immune system to properly recognise the antigen and mount an appropriate response. With CVac this takes place outside the body of the patient (ex vivo), with dendritic cells obtained by leukapheresis. The antigen in this case is MUC1, known to be overexpressed on a variety of cancer cells and in CVac MUC1 is conjugated to the carbohydrate mannan to facilitate uptake by the dendritic cells. CVAc can be administered subcutaneously, whereas Provenge is intravenous.

## Early development in Melbourne

CVac originated in the mid-1990s at the Austin Research Institute, a medical research facility then associated with Melbourne's Austin Hospital (and that merged with the Burnet Institute in 2006). The original version of the product was developed in the laboratory of the Austin Professor Ian McKenzie in 1993. CVac therapy was originally intended to be in vivo but the Austin researchers started getting better results in ex vivo therapy.

## Development by Prima BioMed

Prima BioMed was formed around 2001 to commercialise a number of Austin Research Institute projects including CVac. The company was taken public in July 2001 on the ASX in a reverse takeover of a defunct mineral explorer called Prima Resources. CVac ultimately ended up as Prima BioMed's core project until Prima's acquisition of the French biotechnology company Immutep SA in 2014.

## Dubai Approval

CVac was approved for use by the Dubai Health City Authority in May 2011.

## Manufacturing

CVac was manufactured in Germany by Fraunhofer IZI (Das Fraunhofer-Institut für Zelltherapie und Immunologie), an institute of the Fraunhofer Society in Leipzig, Saxony The Fraunhofer IZI was authorized to manufacture the treatment in Europe in late 2011 after meeting criteria laid down by the German Arzneimittelgesetz (Drug Law). Prima intended that its product would be manufactured at this one central location, with patient blood being flown to Leipzig and primed dendritic cells being shipped back to the relevant trial site.
# La Coloma

La Coloma is a Cuban village and consejo popular ("people's council", i.e. hamlet) of the municipality of Pinar del Río, in Pinar del Río Province. In 2011 it had a population of about 7,000.

## History

The settlement, founded in 1607 and used by the Spanish Empire as a shipyard, due to its natural harbor, was known as Partido San Rosendo until April 30, 1840, when it took the current name. Originally part of the municipality of San Luis, La Coloma passed under the adjacent administration of Pinar del Río in 1977, following the Cuban administrative reform. Prior to that, in the early 1900s, Spaniards began immigrating to Cuba, with some, mostly Galicians, settling in La Coloma. In the 1930s, during the Great Depression, the village suffered from extreme poverty. Later, at the height of the Cuban Revolution, La Coloma served as a strategic location of the 26th of July Movement and was used to smuggle in weapons to aid in the fight against Fulgencio Batista, as well as other acts of sabotage to weaken the efforts of rural guards. This culminated in the takeover and occupation of its Military Naval Port by village residents on January 1, 1959. Today, La Coloma’s main economic driver is the industrial fishing complex building.

## Geography

La Coloma is located on the Gulf of Batabanó, by the Caribbean Coast and the western shore of La Coloma River mouth, in front of Cayos de San Felipe $_{(fr)}$. Among the western Caribbean coast, from Cape San Antonio until Surgidero de Batabanó, in Mayabeque Province, is one of the very few settlements and the largest one.
The village lies 24 km south of Pinar del Río, 21 from San Luis, 32 from San Juan y Martínez, 48 from Consolación del Sur, 52 from Viñales and 83 from Sandino. Playa las Canas, a small village and beach, lies few km west of La Coloma's port.

## Economy

The main economic activity of La Coloma is the fishing industry. The Combinado Pesquero Industrial La Coloma complex, built in 1976, is located by the port.
The administration of the biology station for the National Park Cayos de San Felipe (Nacional Cayos de San Felipe) is also in La Coloma.

## Transport

La Coloma Airport (IATA: LCL, ICAO: MULM) lies 17 km north and serves Pinar del Río, replacing the abandoned Pinar del Río Airport. The village has a seaport on the mouth of La Coloma River, mainly used for fishing activities and with some ferries to Nueva Gerona, in the Isla de la Juventud. It is the southern end of 1-192 highway, crossed by the Carretera Central highway in Pinar del Río; and is 25 km from the A4 motorway Pinar del Río-Havana.
# Rahmbo

The nickname Rahmbo can apply to multiple individuals
* Rahm Emanuel, American politician and diplomat (born 1959)
* Jon Rahm, Spanish golfer (born 1994)
# Roelofsen

Roelofsen is a Dutch patronymic surname ("Roelof's son"). People with this surname include:
* Diane Roelofsen [de; nl] (born 1975), Dutch handball player
* Grant Roelofsen (born 1996), South African cricketer
* Johan Roelofsen (1933–2011), Dutch milkman and inventor of wagon-bed riding
* Marco Roelofsen (born 1969), Dutch association football midfielder
* Pieter Roelofsen (1908–1966), Dutch rower
* Richard Roelofsen (born 1968), Dutch association football striker
* Ruan Roelofse (born 1989), South African tennis player
# Meilyr Brydydd

Meilyr Brydydd ap Mabon (fl. 1100–1137) is the earliest of the Welsh Poets of the Princes or Y Gogynfeirdd (The Less Early Poets) whose work has survived.
Meilyr was the court poet of Gruffudd ap Cynan (ca. 1055–1137), king of Gwynedd. He composed a notable awdl farwnad (elegy) on the death of his patron and a marwysgafn on his own approaching end, noted for its intensity and depth of feeling. He had a son named Gwalchmai ap Meilyr.
# Something in Red (song)

"Something in Red" is a song written and originally recorded by Angela Kaset. Her version was released as a single in the UK by Dover Records on 7 May 1991, and peaked at number 124 in the UK Singles Chart. American country music artist Lorrie Morgan released her version in May 1992 as the fourth single and title track from her second studio album, Something in Red. Morgan's version reached number 14 on the Billboard Hot Country Singles & Tracks chart and peaked at number 10 on the RPM Country Tracks in Canada. The song also earned Morgan her first and only nomination for the Grammy Award for Best Female Country Vocal Performance.
In 2004, British musical theater actress Elaine Paige recorded the song for inclusion on her "best of" compilation album Centre Stage, released the same year.

## Background

Kaset described "Something in Red" in 1992 as a "basic life-of-love kind of story that most people who ever have a relationship go through... the beginning with the red and meeting somebody and wanting to catch their eye".
The song is sung from the perspective of a woman going through the romantic events of her life looking for certain colors for a dress reflecting her current emotional state. For instance, the titular color red grabs the attention of her future lover; while green illustrates envy and jealousy to bring him back after a breakup; white reflects purity and perfection in a wedding dress; and she requests blue for a baby boy, born as she is experiencing a lull in the adventure of her marriage. She concludes the song by looking for a red dress "like the one when I first turned his head", suggesting that the passion has cooled, but is far from dead.

## Charts

| Chart (1991) | Peak position |
| UK Singles Chart (OCC) | 124 |

## Lorrie Morgan version

Morgan came to record the song after Kaset's publisher, Barry and Jewel Coburn, pitched the song to Morgan's producer Barry Beckett and record label RCA Records. Morgan admitted her initial reluctance to record the song, telling the Gannett News Service in 1992, "I just couldn't hear it. I never got past the first verse. I turned if off and said it's not me. I didn't give it a chance because I didn't know what it was about." During the recording of her second studio album, Morgan's new producer Richard Landis also suggested she record the song. She revealed, "I finally got to the third verse and said 'golly, what have I been missing?' Once I got it, it was a hit."

### Music video

The music video was directed by Jim Shea and premiered in March 1992.

### Charts

| Chart (1992) | Peak position |
| Canada Country Tracks (RPM) | 10 |
| US Hot Country Songs (Billboard) | 14 |

#### Year-end charts

| Chart (1992) | Position |
| Canada Country Tracks (RPM) | 93 |
# Kirkjuá

Kirkjuá is a river which runs through the village of Sørvágur in the Faroe Islands. The name Kirkjuá translates to 'Church river', and the name of the river comes from the fact, that it runs in proximity to the church in Sørvágur.
Kirkjuá runs through the valley of Húsadalur and out to the sea.
* This Faroe Islands location article is a stub. You can help Wikipedia by expanding it.
* v
* t
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# K. Balakrishnan Nair

Kesavan Nair Balakrishnan Nair (born 12 April 1948) is a former Judge of Kerala High Court, serving from 2001 to 2010. He was born on 12 April 1948 and was educated at L.P.G. School, Trikalathoor; N.S.S. U.P. School, Mannoor; St. Thomas High School, Keezhillam; Nirmala College, Muvattupuzha and Kerala Law Academy Law College, Thiruvananthapuram.
He was enrolled as an Advocate on the rolls of Bar Council of Kerala on 9 November 1975. Practised at the Civil and Criminal Courts at Muvattupuzha as junior to Late V.A. Joy. Shifted practice to Ernakulam in 1978 as associate of Mr. Justice K.A. Abdul Gafoor and Late K.A. Abraham. Later, practised as junior to late Mr. Justice V. Sivaraman Nair and late Mr. V.M. Nayanar, then Director of Public Prosecutions. In 1988 started independent practice in Civil, Criminal, Labour and Constitutional matters before the High Court of Kerala. Worked as the Standing Counsel for Kerala Agricultural University; Ernakulam and Kollam District Co-operative Banks; Kochi Corporation and Kerala Motor Transport Workers Welfare Fund Board.
He was initially appointed as an Additional Judge of the High Court of Kerala on 7 September 2001 and later, on 27 November 2002 as Permanent Judge. He demitted the office on 11 April 2010. When the Government of Kerala set up an Administrative Tribunal, he was appointed as its First Chairman and assumed office on 03.09.2010. He demitted the office of the Chairman, Kerala Administrative Tribunal, Trivandrum in 2015.
Smt. Girija Balakrishnan a lawyer who joined the Federal Bank is his better half. Shyam Balakrishnan and Meera Balakrishnan are his two children. He has three sisters and one elder brother. Sri. Raveendran Muvattupuzha is his half brother.
# Daryl Jones

Daryl Jones may refer to:
* Daryl Jones (politician) (born 1955), politician from Miami, Florida, United States
* Daryl Jones (baseball) (born 1987), American baseball outfielder
* Daryl Jones (American football) (born 1979), former American football wide receiver
* Daryl Jones (sprinter), winner of the 1982 NCAA Division I outdoor 4 × 400 meter relay championship
# Franz Fischer (cellist)

Franz von Fischer (29 July 1849 – 8 June 1918) was a German cellist and conductor.

## Life

Born in Munich, Fischer started piano lessons at the age of nine, but soon turned to the cello. From 1860 he took lessons in harmony at the Munich Conservatory with the solo cellist Hippolyt Müller and Barraga. Already in 1861 he appeared as a cellist for the first time. 1870 Hans Richter engaged him for three years as a solo cellist at the National Theatre in Pest, where he met his later wife Miczi Környei. In 1875 he was placed by Hans Richter in Bayreuth, where Richard Wagner employed him for two years as a solo répétiteur and held him in high esteem, so that already in 1876 he could participate as a choir conductor in the world premiere of his Ring des Nibelungen. In spring 1877, Wagner even took him to London. From November 1877 until 1880, he was Kapellmeister at the Mannheim National Theatre where he made a name for himself especially as a conductor of Wagner's operas, so that in December 1880, he was invited to perform Wagner's recommendation, he was appointed Kapellmeister at the Munich Court Opera, and only two years later was appointed Court Kapellmeister. In the years 1882, 1883, 1884 and 1899 he conducted the performances of Wagner's Parsifal in Bayreuth in alternation with Hermann Levi. (See Bayreuth premiere cast of Parsifal).
In 1888, he conducted the posthumous premiere of his early opera Die Feen, although there was a conflict with the much younger 3rd Kapellmeister Richard Strauss, who had conducted all rehearsals and felt betrayed.
Beside his tireless work as an opera conductor at the court theatre, where he often stood in for colleagues who were unable to attend, he conducted the famous Odeon concerts of the "Musikalische Akademie" for almost 30 years, from 1883 on, all alone from 1888 to 1892, otherwise mostly the big choir concerts. As a highlight of his career, Fischer conducted the festive concert for the 100th anniversary of the "Musikalische Akademie" on 6 December 1911 with Beethoven's Symphony No. 9.
Fischer died in Munich at the age of 68.
# Cabum

Cabum, born Frank Kwame Gyasi- Frimpong on 15 June 1985, to Ghanaian highlife musician Alhaji Kwame Frimpong (popularly known as Alhaji K. Frimpong) and Joyce Asabia Frimpong, is a Ghanaian rapper from Kumasi.

## Career

After two years of work, he got signed to Rock Entertainment and worked with a few managers including Andy Kem and Yaw Sarpong-Kumankuma. He has since released his first studio album "The Beginning". His slogan or emblem which literally means "Cherish it" normally precedes or ends all his records. He uses that slogan to usher his listeners into his music to cherish his lyrics. Cabum has since shared the stage with Angelique Kidjo and Youssou Ndour at the Mo Ibrahim Freedom Concert.

## Nominations
### Ghana Music Awards

| Year | Nominee / work | Award | Result |
| 2016 | Aka Blay ft Cabum | Highlife Song of the Year | Nominated |
| 2017 | Okyeame Kwame ft. Cabum, Medikal, Sister Derby, | HIP-HOP SONG OF THE YEAR. | Nominated |

## Discography
### Studio albums

* The Beginning

### Singles

* "Dodoodo"
* "Atingya"
* "Style Bea be"
* "Devile in my temple"
* "To be a man"
# Ragnhild Skoftesdotter

Ragnhild Skoftesdotter (12th century) was a Norwegian noblewoman and landowner.

## Life

Ragnhild Skoftesdotter was a daughter of Skofte Ogmundsson (ca. 1040–1103) who was a leading member of the Giske family (Giskeætten) of Sunnmøre and the cousin of King Olav Kyrre who ruled Norway from 1067 until his death in 1093.
Ragnhild Skoftesdotter was married to Dag Eilivsson who was associated with the founding of Gimsøy Abbey. They were the parents of several children, among them Baugeid Dagsdatter. The family resided on the farm Bratsberg (Bratsberg gaard i Gjerpen) in Gjerpen (now Telemark).
Ragnhild Skoftesdotter lived just prior to the beginning of the civil war era in Norway. During a portion of that time, Norway was ruled jointly by three half-brothers; Inge, Sigurd and Eystein. All three were recognized as sons of King Harald Gille and joint heirs to the throne of Norway. This arrangement ultimately resulted in a power-struggle pitting brother against brother.
Ragnhild Skoftesdotter was the mother of two sons (Vatnorm Dagsson and Gregorius Dagsson) both of whom would play key roles within this power-struggle as supporter in the cause of King Inge.
# Roggan River, Quebec

Roggan River is a small village in Northern Quebec, Canada, situated on the Roggan River along a peninsula at the edge of James Bay and Hudson Bay.
# Meilyr ap Gwalchmai

Meilyr ap Gwalchmai (fl. second half of the 12th century) was the son of the Welsh poet Gwalchmai ap Meilyr (fl. 1130–1180) and brother of another poet, Einion ap Gwalchmai. His surviving work is religious in nature.
# Something in Common (Sam Jones album)

Something in Common is a studio album by American jazz bassist Sam Jones, released on September 13, 1977 via the Muse label. The record, with three bonus tracks, was re-released on CD in 2000 and as a digital download in 2009.

## Reception

Professional ratings :
| Review scores ||
| Source | Rating |
| AllMusic | |
Alex Henderson of AllMusic wrote: "In the 1970s, Jones' recordings as a leader were quite consistent, and Something in Common is a rewarding example of the type of solid, hard-swinging bop and post-bop that people expected from him. The only Jones piece that the sextet embraces is "Seven Minds"; other selections were written by Hampton ("Every Man Is a King"), Walton ("Something in Common" and the better known "Bolivia"), and Mitchell ("Blue Silver"). A reviewer with All About Jazz stated: "Jones' only original tune from that 1978 album, Seven Minds, opens the CD with one of his ominous solos, backed by Higgins' cymbaled shimmering and Walton's upper-register ornamentation, before Jones leads into an enthralling, charging modal romp that challenges all of the players."

## Track listing

Three songs, "Shoulders", "One for Amos", and "You Are the Sunshine of My Life", are bonus tracks from the 1974 album, Cedar Walton-Firm Roots, included in later releases.

## Personnel
### Musicians

* Sam Jones – bass
* Blue Mitchell – trumpet
* Billy Higgins – drums
* Bob Berg – sax (tenor)
* Slide Hampton – trombone
* Louis Hayes – drums
* Cedar Walton – keyboards, producer, piano

### Production

* Todd Barkan – compilation producer, liner notes
* Tom Copi – photography
* Thomas Hampson – engineer
* Chuck Irwin – engineer
* Gene Paul – mastering
* Bob Porter – original album producer
* Page Simon – cover design
* Dan Mueller – production coordination
# Kirkjuvatn

Kirkjuvatn is a lake in Suðuroy, Faroe Islands. The lake is located just north of the village of Fámjin, which is located on the west coast of Suðuro]. Fámjin is the only village on the island which is facing directly west. Only one other village, Sumba is also located on the west coast, but Sumba is facing south-west. The name of the lake means Church Lake – kirkja means church and vatn means lake in this case, although the most common meaning of the word vatn is water. The lake is 0.2 km$^2$, the largest lake in the island of Suðuroy. The lake is among the 10 largest lakes in the Faroe Islands.

## Tourism

Kirkjuvatn has become a tourist attraction; tourists often go for a walk from the village to Kirkjuvatn. They can also go fishing to Kirkjuvatn.
# Norzang

Norzang (1403–1466), in full Norbu Zangpo (Tibetan: ཎོར་བུ་བཟང་པོ, Wylie: Nor bu bzang po), was the founder of the power of the Rinpungpa Dynasty in Central Tibet.

## Religious activities

Norzang was the son of Namkha Gyalpo, the chief of the Rinpung fief in Tsang (West Central Tibet). His grandfather Namkha Gyaltsen, the founder of the line, married a sister of the Phagmodrupa ruler Drakpa Gyaltsen. Namkha Gyalpo was one of the principal ministers of the Phagmodrupa dynasty, and the patron of the Tsangrong monastery. Norzang inherited his functions at the early age of eleven and completed the construction of the Chamchen temple. In religious matters he favoured the Sakya and Kagyud sects of Buddhism. According to a somewhat doubtful story a Sakya cleric, the Choje of Ngor, gave religious instructions to Norzang in return for the promise that the Rinpung lord would fulfil three wishes of the Choje. These were to force all members of the rival Geden sect to yield to Sakya, to put an end to the construction of a monastery directed by Gedun Drub (posthumously counted as the first Dalai Lama), and to supply provisions for the female servants of the new monastery at Ngor. Norzang refused the requests since they would cause disturbances.

## Taking power

When the king Drakpa Gyaltsen died in 1432 the succession of the Phagmodrupa throne was in doubt. The influential Norzang recommended that a revered abbot who was a member of the dynasty, the Chenga of Thel, should make the decision. The latter pointed out Drakpa Jungne, nephew of the deceased ruler. In 1434 the old Chenga himself died and the Phagmodrupa were wrecked by a violent internal conflict when Drakpa Jungne's father Sangye Gyaltsen tried to secure power at the expense of his own son. The disturbances enabled the Rinpungpa to take control over the strategic town Shigatse in Tsang in 1435 (or, according to recent research, in 1446 when there was a Phagmodrupa interregnum). The place was later on headed by Norzang's son Dondup Dorje. Seeing this as an act of open defiance against the Phagmodrupa, the elites of Tsang began to ally with the Rinpungpa. Norzang brought various Tibetan petty princes under his authority.

## Later years

In spite of the violent expansion of Norzang's power, he continued to pay formal homage to the Phagmodrupa monarchs Drakpa Jungne (1432–45) and Kunga Lekpa (1448–81). A Rinpungpa lady was given to Kunga Lekpa as his wife. However, the marriage was unhappy, and Kunga Lekpa felt dissatisfied with Norzang's behaviour when he made a tour in Tsang. Norzang and his brother Rinchen Palzang married the Phagmodrupa princess Yeshe Tsogyal, daughter of Sangye Rinchen, thus following the Tibetan practice of polyandry. He or his brother sired three sons in this marriage, namely Upasika (b. 1444), Kunzang (1445–c. 1479), and Dondup Dorje (b. 1447). By a different woman he begot Tsokye Dorje (1450–1510) and Shakya Gyaltsen (1456–1488). He died in 1466, and his death caused a temporary downturn in the fortunes of the Rinpungpa.
# Darin Knight

Darin Knight is an American sound engineer. He won an Oscar for Best Sound for the film The Deer Hunter.

## Selected filmography

* The Deer Hunter (1978)
# Russell Bishop

Russell Bishop may refer to:
* Russell Bishop (academic), New Zealand professor of Māori Education at the University of Waikato
* Russell Bishop (murderer) (1966–2022), British convicted child murderer and sex offender