OpenLLM-France/wikimedia huggingface dataset:
# APOBEC

APOBEC ("apolipoprotein B mRNA editing enzyme, catalytic polypeptide") is a family of evolutionarily conserved cytidine deaminases.

## Function

A mechanism of generating protein diversity is mRNA editing. The APOBEC family of proteins perform mRNA modifications by deaminating cytidine bases to uracil. The N-terminal domain of APOBEC-like proteins is the catalytic domain, while the C-terminal domain is a pseudocatalytic domain. More specifically, the catalytic domain is a zinc dependent cytidine deaminase domain and is essential for cytidine deamination. The positively charged zinc ion in the catalytic domain attracts to the partial-negative charge of RNA.
In the case of APOBEC-1, the mRNA transcript of intestinal apolipoprotein B is altered. RNA editing by APOBEC-1 requires homodimerization and this complex interacts with RNA-binding proteins to form the editosome. The resulting structure interacts with the codon CAA at codon 2153 and deaminates it into UAA, producing a stop codon that results in mRNA that is translated into the intestinal apoB-48 isoform. For other APOBEC-modified transcripts such as in the site-specific deamination of a CGA to a UGA stop codon in neurofibromatosis type 1 (NF1) mRNA, the resulting proteins are predicted to be truncated as well, although these transcripts are possibly degraded.
C-to-U modifications do not always result in the truncation of proteins. For example, in humans/mammals they help protect from viral infections. APOBEC family proteins are widely expressed in cells of the human innate immune system.

## Cancer

These enzymes, when misregulated, are a major source of mutation in numerous cancer types. When the expression of APOBEC family proteins is triggered, accidental mutations in somatic cells can lead to the development of oncogenes, cells which have the potential to develop into a tumor. APOBEC proteins are further expressed in attempt to regulate tumor formation. This makes APOBEC proteins a helpful marker for diagnosing malignant tumors.

## Structure

A 2013 review discussed the structural and biophysical aspects of APOBEC3 family enzymes. Many of the APOBEC protein features are described in the widely studied APOBEC3G's page.

## Family members

Human genes encoding members of the APOBEC protein family include:
* APOBEC1
* APOBEC2
* APOBEC3A
* APOBEC3B
* APOBEC3C
* APOBEC3D ("APOBEC3E" now refers to this)
* APOBEC3F
* APOBEC3G
* APOBEC3H
* APOBEC4
* Activation-induced (cytidine) deaminase (AID)
# Within Sand

Within Sand is a Saudi Arabian film directed by Mohammed Al-Atawi. It features an all-Saudi cast led by Raed Alshammari and tells a tale of survival and self-discovery. The film mark as the first Saudi Arabian film to feature.

## Synopsis

The film follows Snam, a 23-year-old tobacco merchant, on his journey across the desert after being ambushed and left for dead. Snam's quest to reunite with his pregnant wife turns into a harrowing fight for survival as he travels with a wolf trailing him

## Production

Director Mohammed Al-Atawi aimed to capture a genuine relationship between a man and a wolf, showcasing the mysterious beauty of the north Saudi desert. The film's title, Within Sand, reflects the significance of the desert environment where the story unfolds. The production team included over 60% Saudis, with contributions from more than 20 nationalities and local support from Tabuk.

## Release

Within Sand was released in cinemas across Saudi Arabia on February 15, 2024. It received logistical support from NEOM Media Industries and marks Alsarid Films' debut release.
# Orthophytum glabrum

Orthophytum glabrum is a plant species in the genus Orthophytum. This species is native to Brazil.

## Cultivars

* Orthophytum 'Cabernet'
# Gondola Point

Gondola Point is a former Canadian village and current neighborhood of the town of Quispamsis located in Kings County, New Brunswick. It was amalgamated with the town of Quispamsis in 1998.
It is the location site of the Gondola Point Ferry, a cable ferry crossing that connects the Gondola Point Arterial to Route 845 at Reed's Point on the Kingston Peninsula.
It is also the location site of the St. Luke's Anglican Church. Built in 1833, the church is a National Historic Site of Canada and was registered in 2009.

## History

Between May 31 - June 1, 1937, the former Gondola Point schoolhouse was destroyed by a fire, which started around 11 p.m. on the night of May 31. At the time of the fire, the schoolhouse had been unused for multiple years. The origin of the fire was unknown.
On January 1, 1998, the village of Gondola Point, the town of Quispamsis, as well as a portion of the community of Wells merged to form an expanded version of Quispamsis. The former mayor of Gondola Point at the time, Leslie Hamilton-Brown, was named the mayor of the expanded town of Quispamsis.
# X300

X300 may refer to:
* AMD X300 platform, a system on a chip solution for AMD Ryzen processors
* Dell Latitude X300
* ThinkPad X300
* Toshiba Qosmio X300
* Radeon X300
* Jaguar XJ (X300)
# Malang Plain

Malang Plain is a group of nine ash cones, maars and volcanic plugs. It is located around the city of Malang, from southeast to northeast, in East Java, Indonesia. Some of the cones might be parasitic cones from Tengger caldera complex.
# ACRV1

Acrosomal protein SP-10 is a protein that in humans is encoded by the ACRV1 gene.
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
# Outback (lesbian newsletter)

Outback was a lesbian newsletter, self-published in Cornwall from 1996 to 2008. Archives of the newsletter are stored in Kresen Kernow.
# Orthohepadnavirus

Orthohepadnavirus is a genus of viruses, in the family Hepadnaviridae. Humans and other mammals serve as natural hosts. There are 12 species in this genus. Diseases associated with this genus include: hepatitis, hepatocellular carcinoma (chronic infections), and cirrhosis.

## Taxonomy

The genus contains the following species:
* Capuchin monkey hepatitis B virus
* Chinese shrew hepatitis B virus
* Domestic cat hepatitis B virus
* Ground squirrel hepatitis virus
* Hepatitis B virus
* Long-fingered bat hepatitis B virus
* Pomona bat hepatitis B virus
* Roundleaf bat hepatitis B virus
* Taï Forest hepadnavirus
* Tent-making bat hepatitis B virus
* Woodchuck hepatitis virus
* Woolly monkey hepatitis B virus

## Structure

Viruses in the genus Orthohepadnavirus are enveloped, with spherical geometries, and T=4 symmetry. The diameter is around 42 nm. Genomes are circular, around 3.2kb in length. The genome codes for 7 proteins.
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
| Orthohepadnavirus | Icosahedral | T=4 | Non-enveloped | Circular | Monopartite |

## Life cycle

Viral replication is nucleo-cytoplasmic. Replication follows the dsDNA(RT) replication model. DNA-templated transcription, specifically dsDNA(RT) transcription, with some alternative splicing mechanism is the method of transcription. Translation takes place by leaky scanning. The virus exits the host cell by budding, and nuclear pore export. Human and mammals serve as the natural host. Transmission routes are sexual, blood, and contact.
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
| Orthohepadnavirus | Humans; mammals | Hepatocytes | Cell receptor endocytosis | Budding | Nucleus | Cytoplasm | Vertical: parental; sex; blood |
# List of governors of Burgenland

This is a list of governors of the Austrian state of Burgenland:
| No. | Portrait | Name | Term | Term | Term | Party | Party | Period |
| No. | Portrait | Name | Took office | Left office | Duration | Party | Party | Period |
| 1 | | Robert Davy as Landesverwalter | 10 March 1921 | 5 March 1922 | | | Independent | First Republic (1921–1934) |
| 2 | | Alfred Rausnitz | 5 March 1922 | 14 July 1923 | | | Independent | First Republic (1921–1934) |
| 3 | | Alfred Walheim | 14 July 1923 | 4 January 1924 | | | Greater German | First Republic (1921–1934) |
| 4 | | Josef Rauhofer | 4 January 1924 | 10 January 1928 | | | Christian Social | First Republic (1921–1934) |
| 5 | | Anton Schreiner | 10 January 1928 | 24 July 1929 | | | Christian Social | First Republic (1921–1934) |
| 6 | | Johann Thullner | 24 July 1929 | 10 December 1930 | | | Christian Social | First Republic (1921–1934) |
| (5) | | Anton Schreiner | 10 December 1930 | 25 November 1931 | | | Christian Social | First Republic (1921–1934) |
| (3) | | Alfred Walheim | 25 November 1931 | 22 February 1934 | | | Landbund | First Republic (1921–1934) |
| 7 | | Hans Sylvester | 22 February 1934 | 11 March 1938 | | | Fatherland's Front | Austrofascism (1934–1938) |
| 8 | | Tobias Portschy | 11 March 1938 | 15 October 1938 | | | NSDAP | Nazi Germany (1938–1945) |
| Nazi Germany (1938–1945) ||||||||
| 9 | | Ludwig Leser | 1 October 1945 | 4 January 1946 | | | SPÖ | Second Republic (1945–present) |
| 10 | | Lorenz Karall | 4 January 1946 | 22 June 1956 | | | ÖVP | Second Republic (1945–present) |
| 11 | | Johann Wagner | 22 June 1956 | 8 August 1961 | | | ÖVP | Second Republic (1945–present) |
| 12 | | Josef Lentsch | 8 August 1961 | 12 June 1964 | | | ÖVP | Second Republic (1945–present) |
| 13 | | Hans Bögl | 12 June 1964 | 28 June 1966 | | | SPÖ | Second Republic (1945–present) |
| 14 | | Theodor Kery | 28 June 1966 | 30 October 1987 | | | SPÖ | Second Republic (1945–present) |
| 15 | | Johann Sipötz | 30 October 1987 | 18 July 1991 | | | SPÖ | Second Republic (1945–present) |
| 16 | | Karl Stix | 18 July 1991 | 27 December 2000 | | | SPÖ | Second Republic (1945–present) |
| 17 | | Hans Niessl | 28 December 2000 | 28 February 2019 | | | SPÖ | Second Republic (1945–present) |
| 18 | | Hans Peter Doskozil | 28 February 2019 | Incumbent | | | SPÖ | Second Republic (1945–present) |
# CopSSH

CopSSH is an implementation of OpenSSH for Windows. CopSSH offers both SSH client and server functionality and can be used for remote administration of Windows systems. CopSSH contains DLLs from the Cygwin Linux environment and a version of OpenSSH compiled from Cygwin. An administration GUI is also provided as of version 4.0.0.

## History

The first version of CopSSH was developed in mid-2003 and was published as a free package on the Security Focus Secure Shell mailing list. CopSSH has since then become very well known and has been given various updates with newer versions of its underlying solutions.

## Features

The CopSSH client can be used to initiate SSH/SFTP/SCP connections, while the CopSSH server is used as the SSH or SFTP server.
CopSSH administration GUI has the following features:
* Service, connection, and event status
* User Access Control with activation wizard
* Public Key Administration with PKA wizard
* SSH Server Configuration
* SFTP Server Configuration
# Maeve Gilroy

Maeve Gilroy is a former camogie player, winner of the Cuchulainn award in 1966 and of All Ireland medals in 1956 and 1967.

## Career

Gilroy was already regarded as one of the country's best players when she scored two goals for Antrim against Dublin in the historic 1956 All Ireland semi-final, a match that prevented Dublin winning 19 All Ireland titles in a row. She was goalscorer and lead forward on the first ever Queen's University Belfast team to defeat UCD, by a score of 3–1 to 3–0 in the Ashbourne Cup of 1959, but the cup went to UCD at the end of the round-robin series. When the competition reverted to knock-out in 1961, she was on the QUB team that beat UCC 7–2 to 2–1 at Cherryvale in the Ashbourne Cup semi-final, alongside Margaret Treacy, Eileen Maguire and Maire O’Kane.
Playing in defence through the second half of her career, she was playmaker for the team that defeated Dublin in a 1967 replay and for the Ulster team that won their first Gael Linn Cup in 1967. She continued to play until Antrim's defeat in the All Ireland final of 1969.

## Coach and referee

She coached the Queens' University Ashbourne Cup teams in the 1960s and refereed matches up to All Ireland level, taking charge of the All Ireland finals of 1961 and 1962.
# Wu Qiuhua

Wu Qiuhua (born 21 June 1959) is a Chinese fencer. She competed in the women's team foil event at the 1984 Summer Olympics.
# Malikzada Manzoor Ahmad

Malikzada Manzoor Ahmad (born Malikzada Manzuur Ahmad; 17 October 1929 – 22 April 2016) was an Indian Urdu poet, composer, compere, educationist and humorist. Primarily known for compering mushairas in India and abroad and contributing to Urdu literature, he also compered the DCM mushaira, India–Pakistan poetry conference from 1952 to 2016. He also compered the India–Pakistan mushaira in Ambala and in the Red Fort.

## Biography

He was born as Malikzada Manzuur Ahmad in Ambedkar Nagar, Uttar Pradesh. He wrote novels, poetry and prose such as College Girl (1954 novel), Urdu Ka Mas’laa (1957 monograph), Shahr-e-Sukhan (1961 poetry), and Raqs-e-Sharar (2004 autobiography).
He also wrote numerous uncertain books such as autobiography and poetry, however his work was focused on research by scholarly topics related to Urdu poetry. He was awarded three PhD degrees by Jammu University, Nagpur University and Gorakhpur University. He was later awarded an MPhil degree by an uncertain university.
He served at various universities such as lecturer of history in Mahrajganj, Azamgarh, lecturer of English in Azamgarh and lecturer of Urdu in Gorakhpur University. He retired as professor of Urdu from Lucknow University.
He served as a president of Urdu Academy, Uttar Pradesh, chairman of government of Uttar Pradesh's Fakhruddin Ali Ahmad Memorial Committee, member executive council for the National Council for Promotion of Urdu Language besides serving as the member of Prasar Bharati and member executive council for Lucknow University among others.
He was the recipient of eighty uncertain awards in recognition of his contribution to Urdu literature.

## Death

He was suffering from cardiovascular disease and was admitted to a private hospital two days before he died on 22 Apr 2016 in Lucknow.
# ACS-Itaipu Sora-E

The Sora-E is a two-seat electric powered aircraft. It is a joint venture between ACS Aviation of Brazil and Itaipu Binacional of Paraguay.

## Development

The Sora-E is a side-by-side two seat low wing tri-cycle gear aircraft of composite construction. A Slovenian electric engine is powered by six lithium-ion polymer (LiPo) batteries.

## Specifications (Sora-E)

Data from AVweb
General characteristics
* Crew: 1
* Capacity: 1 passenger
* Powerplant: 1 × electric motor
Performance
* Cruise speed: 190 km/h (120 mph, 100 kn)
# Origanum × hybridum

Origanum × hybridum, synonym Origanum × pulchellum, is an ornamental plant of hybrid origin. Its two parents are O. dictamnus and O. sipyleum. It is known as the showy marjoram or the showy oregano.
# Cora ixtlanensis

Cora ixtlanensis is a species of basidiolichen in the family Hygrophoraceae. Found in Mexico, it was formally described as a new species in 2019 by Bibiana Moncada, Rosa Emilia Pérez-Pérez, and Robert Lücking. The type specimen was collected in Cerro Pelón (Santiago Comaltepec, Oaxaca) in a cloud forest at an altitude of 2,990 m (9,810 ft). The lichen is only known from the type locality, where it grows terrestrially. The specific epithet refers to the Ixtlán community in Ixtlán de Juárez, who, according to the authors, are "renowned for their sustainable ecosystem management and ecotourism".
# Suwannee, Florida

Suwannee is an unincorporated community in Dixie County, Florida, United States. It is located on the Suwannee River near its mouth, at the southern end of the Big Bend region of Florida. It is 23 miles southwest of Old Town, to which it is connected by County Road 349.
Suwannee is a fishing village, with a population of about 300. It caters for both freshwater fishing in the river and saltwater fishing in the Gulf of Mexico. During the 19th century, the area on which the town sits was an important staging ground for goods traveling to and from the cotton and tobacco plantations throughout the Suwannee Valley. The 1939 Florida guide notes that "small wood-burning sternwheelers of the Mississippi type plied the lower stretches of the Suwannee, carrying cotton, tobacco, peanuts, naval stores, and lumber from the interior to the high-masted schooners anchored at the river mouth. The Belle of the Suwannee, Captain Robert Bartlett commanding, was the queen of the fleet. During the war blockade runners traveled up and down the stream; several were burned and sunk, but many succeeded in eluding the Federal gunboats."
The town is surrounded by the Lower Suwannee National Wildlife Refuge. There is a canoe/kayak trail into the refuge from launch sites in the town.
# Gongora (disambiguation)

Gongora is a genus of orchids, named after Antonio Caballero y Góngora.
Gongora may also refer to:
* Luis de Góngora (1561-1627), Spanish poet frequently known as "Góngora"
* Góngora (surname)
# Syzygium tenuifolium

Syzygium tenuifolium is a species of plant in the family Myrtaceae. It is a tree endemic to Peninsular Malaysia. Under the synonym Pseudoeugenia tenuifolia, it was classed as endangered and threatened by habitat loss.
# AH84

Asian Highway 84 (AH84) is a road in the Asian Highway Network running 1074 km (667 miles) from Doğubeyazıt to Mersin, Turkey. The route is concurrent with European route E90 and European route E99. The route is as follows:

## Turkey

* D.975 Road D975: Doğubeyazıt - Muradiye
* D.280 Road D280: Muradiye - Erciş
* D.290 Road D290: Erciş - Adilcevaz
* D.965 Road D965: Adilcevaz - Baykan
* D.360 Road D360: Baykan - Diyarbakır - Siverek
* D.885 Road D885: Siverek - Şanlıurfa
* Otoyol 52: Şanlıurfa - Gaziantep - Toprakkale - Adana
** Branch Otoyol 53: Toprakkale - Iskenderun
* Otoyol 50: Adana
* Otoyol 51: Adana - Mersin
* This article related to a road in Asia is a stub. You can help Wikipedia by expanding it.
* v
* t
* e
# Otto Hoynck

Otto Hoynck (1630, The Hague – after 1706), was a Dutch Golden Age portrait painter active in England.

## Biography

According to the RKD he was trained in The Hague as a pupil of Arnold van Ravesteyn and Pieter Hermansz Verelst (Verelst became his father-in-law). He moved to England after being registered in Amsterdam in 1686. Jacob Campo Weyerman listed him as Otto Hoijink.
# William Sinclaire

William Sinclaire is an American polo player.

## Biography

As a player, he was on the winning USA team in the Camacho Cup series with Mexico in 1975, and he won the Butler Handicap in 1976.
Shortly after the Second World War, he helped develop polo in the Rocky Mountain area, especially around Denver, Colorado. He served as Governor of the United States Polo Association (USPA) from 1969 to 1971, Treasurer from 1971 to 1973, Vice President from 1973 to 1976, President from 1976 to 1980, and Chairman from 1980 to 1984. He now serves as Honorary Governor. In 1989, he was awarded the Hugo Dalmar Award from the USPA.
He was inducted into the Museum of Polo and Hall of Fame on February 16, 2007.
# Andrew Mead

Andrew MacDonald Mead (born 1952) is a justice of the Maine Supreme Judicial Court since 2007. His current term expires in 2021.
Mead attended the University of Maine and New York Law School.
He has been a member of the Bangor law firms of Paine, Lynch & Weatherbee and Mitchell & Stearns. He is a past President of the Maine State Bar Association. He was appointed to the Maine District Court in 1990 and the Maine Superior Court in 1992. He served as chief justice of the Maine Superior Court from 1999 to 2001. He was appointed to the Maine Supreme Judicial Court in 2007. He has served as judicial liaison to the Maine Rules of Evidence Advisory Committee and chaired the Task Force on Electronic Court Records. He has been active in a number of court technology and jury reform initiatives. He is a member of the University of Maine adjunct faculty.
# Cosmisoma scopulicorne

Cosmisoma scopulicorne is a species of beetle in the family Cerambycidae. It was described by William Kirby in 1818.
# Suwannee Canal Company

Chartered in 1890, the Suwannee Canal Company (also seen as the Suwanee Canal Company) had attempted to drain the Okefenokee Swamp. The company had hoped that they could sell the drained land for various agricultural plantations. The company also built a cypress lumber sawmill and the Brunswick and Pensacola Railroad to haul the lumber. The company went bankrupt in 1897.

## History

There was an early attempt to survey and sell land in the Okekenokee swamp through a Georgia state land in the early 1800s, though many of these lots were not claimed. Starting in the early 1850s, various land speculators attempted acquisition of swap land from Georgia, yet most of these contracts were never completed and the land reverted to the state. In 1889, the Georgia Legislature approved a plan to auction the swamp and requested bids for the state land on March 18, 1890. The winning bid of 26.5 cents per acre was tendered by syndics Henry Jackson, Frank Coxe, Marshall A. Phillips, H.S. Little, and PMB Young, who incorporated as the Suwannee Canal Company.