# 2022 I.ČLTK Prague Open – Women's singles

Jule Niemeier was the defending champion but chose not to participate.
Maja Chwalińska won the title, defeating Ekaterine Gorgodze in the final, 7–5, 6–3.

## Seeds

* Ekaterine Gorgodze (final)
* Réka Luca Jani (quarterfinals)
* Yuan Yue (first round)
* Despina Papamichail (first round)
* Rebecca Šramková (first round)
* Valentini Grammatikopoulou (first round)
* Suzan Lamens (withdrew)
* Lizette Cabrera (quarterfinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 1 | Ekaterine Gorgodze | 6 | 6 | | | | |
| | Fernanda Contreras | 4 | 3 | | | | |
| | Fernanda Contreras | 4 | 3 | 1 | Ekaterine Gorgodze | 5 | 3 |
| | | | | | Maja Chwalińska | 7 | 6 |
| | Maja Chwalińska | 7 | 6 | | Maja Chwalińska | 7 | 6 |
| WC | Miriam Kolodziejová | 5 | 2 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | E Gorgodze | 6 | 6 | | | | | | | | | | | | | | |
| Q | L Meyer auf der Heide | 1 | 4 | | 1 | E Gorgodze | 6 | 6 | | | | | | | | | |
| | C McNally | 6 | 6 | | | C McNally | 4 | 0 | | | | | | | | | |
| Q | L Klimovičová | 3 | 3 | | | | | | | 1 | E Gorgodze | 6 | 6 | | | | |
| LL | AS Sánchez | 4 | 4 | | | | | | | 8 | L Cabrera | 2 | 2 | | | | |
| | J Malečková | 6 | 6 | | | J Malečková | 6 | 5 | 5 | | | | | | | | |
| Q | N Hanatani | 3 | 3 | | 8 | L Cabrera | 2 | 7 | 7 | | | | | | | | |
| 8 | L Cabrera | 6 | 6 | | | | | | | | | | | 1 | E Gorgodze | 6 | 6 |
| 3 | Y Yuan | 2 | 2 | | | | | | | | | | | | F Contreras | 4 | 3 |
| Q | N Stevanović | 6 | 6 | | Q | N Stevanović | 5 | 3 | | | | | | | | | |
| Q | A Prisăcariu | 6$^3$ | 6 | 7$^7$ | Q | A Prisăcariu | 7 | 6 | | | | | | | | | |
| WC | B Palicová | 7$^7$ | 3 | 6$^4$ | | | | | | Q | A Prisăcariu | 3 | 6$^4$ | | | | |
| | F Contreras | 6 | 6$^6$ | 6 | | | | | | | F Contreras | 6 | 7$^7$ | | | | |
| Q | A Laboutková | 4 | 7$^8$ | 3 | | F Contreras | 3 | 6 | 7 | | | | | | | | |
| PR | P Hon | 6 | 6 | | PR | P Hon | 6 | 4 | 5 | | | | | | | | |
| 5 | R Šramková | 2 | 1 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| Q | A Dețiuc | 2 | 5 | | | | | | | | | | | | | | | |
| | B Gatica | 6 | 7 | | | B Gatica | 7$^7$ | 6 | | | | | | | | | | |
| WC | D Lopatetska | 7 | 1 | 2 | Q | D Šalková | 6$^4$ | 3 | | | | | | | | | | |
| Q | D Šalková | 5 | 6 | 6 | | | | | | | B Gatica | 6$^2$ | 1 | | | | | |
| | L Nosková | 1 | 1 | | | | | | | | M Chwalińska | 7$^7$ | 6 | | | | | |
| SE | N Bartůňková | 6 | 6 | | SE | N Bartůňková | 3 | 0 | | | | | | | | | | |
| | M Chwalińska | 7$^7$ | 6 | | | M Chwalińska | 6 | 6 | | | | | | | | | | |
| 4 | D Papamichail | 6$^2$ | 1 | | | | | | | | | | | | | M Chwalińska | 7 | 6 |
| 6 | V Grammatikopoulou | 4 | 2 | | | | | | | | | | | | WC | M Kolodziejová | 5 | 2 |
| | S Bandecchi | 6 | 6 | | | S Bandecchi | 5 | 3 | | | | | | | | | | |
| WC | L Havlíčková | 4 | 6$^4$ | | WC | M Kolodziejová | 7 | 6 | | | | | | | | | | |
| WC | M Kolodziejová | 6 | 7$^7$ | | | | | | | WC | M Kolodziejová | 4 | 7 | 6 | | | | |
| | C Alves | 4 | 7$^7$ | 3 | | | | | | 2 | RL Jani | 6 | 5 | 2 | | | | |
| | M Uchijima | 6 | 6$^5$ | 6 | | M Uchijima | 1 | 6 | 4 | | | | | | | | | |
| | H Chang | 0 | 6 | 2 | 2 | RL Jani | 6 | 4 | 6 | | | | | | | | | |
| 2 | RL Jani | 6 | 4 | 6 | | | | | | | | | | | | | | |