# 2016 Karshi Challenger – Singles

Teymuraz Gabashvili was the defending champion but chose not to participate.
Marko Tepavac won the title after defeating Dudi Sela 2–6, 6–3, 7–6$^{(7–4)}$ in the final.

## Seeds

* Dudi Sela (final)
* Karen Khachanov (quarterfinals)
* Radu Albot (semifinals)
* Aleksandr Nedovyesov (second round)
* Amir Weintraub (first round)
* Denys Molchanov (first round)
* Dmitry Popko (quarterfinals)
* Aslan Karatsev (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| 1 | Dudi Sela | 6 | 6 | | | | | | |
| 3 | Radu Albot | 4 | 4 | | | | | | |
| 3 | Radu Albot | 4 | 4 | | 1 | Dudi Sela | 6 | 3 | 6$^4$ |
| | | | | | | Marko Tepavac | 2 | 6 | 7$^7$ |
| | Ilya Ivashka | 4 | 6 | 5 | | Marko Tepavac | 2 | 6 | 7$^7$ |
| | Marko Tepavac | 6 | 3 | 7 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | D Sela | 6 | 2 | | | | | | | | | | | | | | | |
| Q | S Betov | 1 | 1$^r$ | | 1 | D Sela | 6 | 6 | | | | | | | | | | |
| WC | Pavel Tsoy | 1 | 3 | | | N Milojević | 1 | 2 | | | | | | | | | | |
| | N Milojević | 6 | 6 | | | | | | | 1 | D Sela | 6$^5$ | 7$^7$ | 6 | | | | |
| | A Velotti | 6 | 6 | | | | | | | 7 | D Popko | 7$^7$ | 6$^3$ | 4 | | | | |
| Q | D Matsukevich | 1 | 4 | | | A Velotti | 6 | 5 | 4 | | | | | | | | | |
| Q | Francesco Vilardo | 3 | 6 | 6$^4$ | 7 | D Popko | 4 | 7 | 6 | | | | | | | | | |
| 7 | D Popko | 6 | 1 | 7$^7$ | | | | | | | | | | | 1 | D Sela | 6 | 6 |
| 3 | R Albot | 7$^7$ | 6 | | | | | | | | | | | | 3 | R Albot | 4 | 4 |
| WC | S Fayziev | 6$^3$ | 4 | | 3 | R Albot | 6 | 6 | | | | | | | | | | |
| | C Zampieri | 2 | 6$^4$ | | | N Barrientos | 0 | 1 | | | | | | | | | | |
| | N Barrientos | 6 | 7$^7$ | | | | | | | 3 | R Albot | 7$^7$ | 2 | 6 | | | | |
| | L Harris | 7 | 3 | 3 | | | | | | | M Dubarenco | 6$^2$ | 6 | 0 | | | | |
| | M Dubarenco | 5 | 6 | 6 | | M Dubarenco | 6 | 6 | | | | | | | | | | |
| | A Bossel | 4 | 6 | 3 | 8 | A Karatsev | 1 | 2 | | | | | | | | | | |
| 8 | A Karatsev | 6 | 4 | 6 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | D Molchanov | 6$^7$ | 2 | | | | | | | | | | | | | | |
| Q | R Muzaev | 7$^9$ | 6 | | Q | R Muzaev | 1 | 4 | | | | | | | | | |
| | S Diez | 6 | 7$^9$ | | | S Diez | 6 | 6 | | | | | | | | | |
| | S Griekspoor | 2 | 6$^7$ | | | | | | | | S Diez | 3 | 1 | | | | |
| WC | T Ismailov | 5 | 4 | | | | | | | | I Ivashka | 6 | 6 | | | | |
| | I Ivashka | 7 | 6 | | | I Ivashka | 6 | 3 | 6 | | | | | | | | |
| | E López-Pérez | 3 | 6 | 3 | 4 | A Nedovyesov | 3 | 6 | 2 | | | | | | | | |
| 4 | A Nedovyesov | 6 | 4 | 6 | | | | | | | | | | I Ivashka | 4 | 6 | 5 |
| 5 | A Weintraub | 4 | 2 | | | | | | | | | | | M Tepavac | 6 | 3 | 7 |
| | A Bega | 6 | 6 | | | A Bega | 5 | 4 | | | | | | | | | |
| | T-h Yang | 3 | 1 | | | M Tepavac | 7 | 6 | | | | | | | | | |
| | M Tepavac | 6 | 6 | | | | | | | | M Tepavac | 7$^7$ | 6 | | | | |
| WC | Shonigmatjon Shofayziyev | 7$^8$ | 2 | 6$^2$ | | | | | | 2 | K Khachanov | 6$^5$ | 4 | | | | |
| LL | S Barry | 6$^6$ | 6 | 7$^7$ | LL | S Barry | 1 | 4 | | | | | | | | | |
| | A Metreveli | 2 | 2 | | 2 | K Khachanov | 6 | 6 | | | | | | | | | |
| 2 | K Khachanov | 6 | 6 | | | | | | | | | | | | | | |