# 2022 Open Ciudad de Valencia – Singles

Arantxa Rus was the defending champion but lost in the second round to Leyre Romero Gormaz.
Marina Bassols Ribera won the title, defeating Ylena In-Albon in the final, 6–4, 6–0.

## Seeds

* Tamara Korpatsch (semifinals)
* Cristina Bucșa (first round)
* Océane Dodin (quarterfinals, retired)
* Kristina Mladenovic (first round, retired)
* Magdalena Fręch (second round, retired)
* Arantxa Rus (second round)
* Alycia Parks (semifinals)
* Rebeka Masarova (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| 1 | Tamara Korpatsch | 3 | 1 | | | |
| | Marina Bassols Ribera | 6 | 6 | | | |
| | Marina Bassols Ribera | 6 | 6 | Marina Bassols Ribera | 6 | 6 |
| | | | | Ylena In-Albon | 4 | 0 |
| 7 | Alycia Parks | 5 | 6$^4$ | Ylena In-Albon | 4 | 0 |
| | Ylena In-Albon | 7 | 7$^7$ | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | T Korpatsch | 6 | 7 | | | | | | | | | | | | | |
| LL | Ç Büyükakçay | 4 | 5 | | 1 | T Korpatsch | 6 | 6 | | | | | | | | |
| WC | M Ristić | 6 | 0 | 0 | WC | I Burillo Escorihuela | 1 | 3 | | | | | | | | |
| WC | I Burillo Escorihuela | 1 | 6 | 6 | | | | | 1 | T Korpatsch | 6 | 6 | | | | |
| LL | A Prisăcariu | 1 | 2 | | | | | | | J Bouzas Maneiro | 4 | 1 | | | | |
| | J Bouzas Maneiro | 6 | 6 | | | J Bouzas Maneiro | 6 | 3 | | | | | | | | |
| | I Khromacheva | 1 | 4 | | 5 | M Fręch | 0 | 0$^r$ | | | | | | | | |
| 5 | M Fręch | 6 | 6 | | | | | | | | | | 1 | T Korpatsch | 3 | 1 |
| 4 | K Mladenovic | 1 | 0$^r$ | | | | | | | | | | | M Bassols Ribera | 6 | 6 |
| | C Monnet | 6 | 2 | | | C Monnet | 2 | 1 | | | | | | | | |
| | M Bassols Ribera | 4 | 6 | 6 | | M Bassols Ribera | 6 | 6 | | | | | | | | |
| Q | I Shymanovich | 6 | 0 | 2 | | | | | | M Bassols Ribera | 6 | 7 | | | | |
| Q | A Moratelli | 2 | 1 | | | | | | | L Romero Gormaz | 0 | 5 | | | | |
| | L Romero Gormaz | 6 | 6 | | | L Romero Gormaz | 6 | 6 | | | | | | | | |
| Q | L Nguyen Tan | 0 | 0 | | 6 | A Rus | 2 | 4 | | | | | | | | |
| 6 | A Rus | 6 | 6 | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 7 | A Parks | 6 | 6 | | | | | | | | | | | | | |
| LL | C Scholl | 1 | 1 | 7 | A Parks | 6$^3$ | 6 | 6 | | | | | | | | |
| | C Rosatello | 2 | 2 | Q | F Curmi | 7$^7$ | 0 | 4 | | | | | | | | |
| Q | F Curmi | 6 | 6 | | | | | | 7 | A Parks | 6 | 3 | | | | |
| | A Bolsova | 7$^7$ | 6 | | | | | | 3 | O Dodin | 0 | 0$^r$ | | | | |
| Q | N Brancaccio | 6$^3$ | 4 | | A Bolsova | 3 | 4 | | | | | | | | | |
| LL | IG Ghioroaie | 3 | 3 | 3 | O Dodin | 6 | 6 | | | | | | | | | |
| 3 | O Dodin | 6 | 6 | | | | | | | | | | 7 | A Parks | 5 | 6$^4$ |
| 8 | R Masarova | 6 | 6 | | | | | | | | | | | Y In-Albon | 7 | 7$^7$ |
| WC | A Lázaro García | 0 | 3 | 8 | R Masarova | 6 | 6$^3$ | 4 | | | | | | | | |
| Q | C Hoste Ferrer | 3 | 3 | Q | V Erjavec | 2 | 7$^7$ | 6 | | | | | | | | |
| Q | V Erjavec | 6 | 6 | | | | | | Q | V Erjavec | 3 | 5 | | | | |
| | D Papamichail | 4 | 3 | | | | | | | Y In-Albon | 6 | 7 | | | | |
| Q | S Nahimana | 6 | 6 | Q | S Nahimana | 4 | 0$^r$ | | | | | | | | | |
| | Y In-Albon | 6 | 6 | | Y In-Albon | 6 | 2 | | | | | | | | | |
| 2 | C Bucșa | 2 | 2 | | | | | | | | | | | | | |