# 2021 Macha Lake Open – Singles

Barbora Krejčíková was the defending champion, having won the previous edition in 2019, but chose not to participate.
Zheng Qinwen won the title, defeating Aleksandra Krunić in the final, 7–6$^{(7–5)}$, 6–3.

## Seeds

* Kristína Kučová (first round)
* Çağla Büyükakçay (first round)
* Allie Kiick (first round, retired)
* Réka Luca Jani (quarterfinals)
* Rebecca Šramková (first round)
* Julia Grabher (second round)
* Verónica Cepede Royg (first round)
* Gabriela Talabă (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| | Zheng Qinwen | 7 | 6 | | | |
| WC | Linda Nosková | 5 | 4 | | | |
| WC | Linda Nosková | 5 | 4 | Zheng Qinwen | 7$^7$ | 6 |
| | | | | Aleksandra Krunić | 6$^5$ | 3 |
| | Aleksandra Krunić | 6 | 6 | Aleksandra Krunić | 6$^5$ | 3 |
| | Alexandra Cadanțu | 2 | 4 | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | K Kučová | 0 | 3 | | | | | | | | | | | | | | |
| | Q Zheng | 6 | 6 | | | Q Zheng | 4 | | | | | | | | | | |
| | R Hogenkamp | 3 | 6 | 1 | | V Kan | 0$^r$ | | | | | | | | | | |
| | V Kan | 6 | 4 | 6 | | | | | | | Q Zheng | 7$^7$ | 6 | | | | |
| Q | İ Öz | 1 | 1 | | | | | | | | T Mrdeža | 6$^2$ | 2 | | | | |
| | T Mrdeža | 6 | 6 | | | T Mrdeža | 7 | 6$^2$ | 6 | | | | | | | | |
| WC | D Viďmanová | 6 | 2 | 4 | 6 | J Grabher | 5 | 7$^7$ | 3 | | | | | | | | |
| 6 | J Grabher | 4 | 6 | 6 | | | | | | | | | | | Q Zheng | 7 | 6 |
| 3 | A Kiick | 1$^r$ | | | | | | | | | | | | WC | L Nosková | 5 | 4 |
| | K Gerlach | 4 | | | | K Gerlach | 1 | 6 | 1 | | | | | | | | |
| Q | D Šalková | 4 | 7$^7$ | 3 | Q | I Burillo Escorihuela | 6 | 3 | 6 | | | | | | | | |
| Q | I Burillo Escorihuela | 6 | 6$^4$ | 6 | | | | | | Q | I Burillo Escorihuela | 5 | 2 | | | | |
| | A Bondár | 6 | 6 | | | | | | | WC | L Nosková | 7 | 6 | | | | |
| Q | M Kolodziejová | 4 | 4 | | | A Bondár | 1 | 7$^7$ | 5 | | | | | | | | |
| WC | L Nosková | 7$^7$ | 6 | | WC | L Nosková | 6 | 6$^2$ | 7 | | | | | | | | |
| 7 | V Cepede Royg | 6$^5$ | 4 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals |
| 8 | G Talabă | 6 | 6 | | | | | | | | | | | | | |
| Q | K Zimmermann | 2 | 3 | | 8 | G Talabă | 5 | 1 | | | | | | | | |
| Q | A Prisăcariu | 6 | 3 | 2 | | A Krunić | 7 | 6 | | | | | | | | |
| | A Krunić | 3 | 6 | 6 | | | | | | A Krunić | 6 | 3 | 6 | | | |
| | W Osuigwe | 6 | 6$^3$ | 4 | | | | | 4 | RL Jani | 2 | 6 | 3 | | | |
| WC | S Bejlek | 2 | 7$^7$ | 6 | WC | S Bejlek | 4 | 3 | | | | | | | | |
| | S Waltert | 4 | 6 | 4 | 4 | RL Jani | 6 | 6 | | | | | | | | |
| 4 | RL Jani | 6 | 2 | 6 | | | | | | | | | | A Krunić | 6 | 6 |
| 5 | R Šramková | 6 | 3 | 4 | | | | | | | | | | A Cadanțu | 2 | 4 |
| WC | N Bartůňková | 1 | 6 | 6 | WC | N Bartůňková | 6$^4$ | 1 | | | | | | | | |
| PR | D Aiava | 3 | 3 | | | A Cadanțu | 7$^7$ | 6 | | | | | | | | |
| | A Cadanțu | 6 | 6 | | | | | | | A Cadanțu | 5 | 6 | 4 | | | |
| Q | T Smitková | 6 | 6 | | | | | | PR | A Dulgheru | 7 | 1 | 1$^r$ | | | |
| Q | J Marková | 3 | 4 | | Q | T Smitková | 6$^4$ | 1 | | | | | | | | |
| PR | A Dulgheru | 6 | 6 | | PR | A Dulgheru | 7$^7$ | 6 | | | | | | | | |
| 2 | Ç Büyükakçay | 2 | 4 | | | | | | | | | | | | | |