OpenLLM-France/wikimedia huggingface dataset:
# Matrix metallopeptidase 13

Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene. It is a member of the matrix metalloproteinase (MMP) family. Like most MMPs, it is secreted as an inactive pro-form. MMP-13 has a predicted molecular weight around 54 kDa. It is activated once the pro-domain is cleaved, leaving an active enzyme composed of the catalytic domain and the hemopexin-like domain PDB: 1PEX​. Although the actual mechanism has not been described, the hemopexin domain participates in collagen degradation, the catalytic domain alone being particularly inefficient in collagen degradation. During embryonic development, MMP-13 is expressed in the skeleton as required for restructuring the collagen matrix for bone mineralization. In pathological situations it is highly overexpressed; this occurs in human carcinomas, rheumatoid arthritis and osteoarthritis.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

## Regulation

Transcriptional regulation of MMP-13 is tightly controlled due to its potent proteolytic capacity. There are several binding domains for various transcription factors including AP-1, PEA-3 and OSE-2 as well as a sequence with homology to a TGF-β inhibitory element (TIE). Moreover, several cytokines and growth factors have been demonstrated to affect Mmp13 gene expression, including parathyroid hormone, IGF-1, TGF-β, hepatocyte growth factor and many inflammatory cytokines such as IL-1α and IL-1β.
The upstream regulatory region of the Mmp13 gene contains a number of transcription factor binding sites but it was recently discovered that there is a conserved forkhead response element (FHRE) consensus sequence for FOXO3a in the human, mouse and rat Mmp13 promoter. Endogenous FOXO3a activation results in marked upregulation of Mmp13 expression which is capable of promoting extracellular matrix degradation and apoptotic cell death.

## Clinical Relevance

MMP-13 has long been a protein of interest in the context of osteoarthritis and rheumatoid arthritis.
The role of MMP-13 has also been thoroughly examined in atherosclerosis, specifically in potentially reducing the collagen content of the fibrous cap.
# Matsumyia nigrofacies

Matsumyia nigrofacies is a species of hoverfly in the family Syrphidae.

## Distribution

Japan.
# Moira (Moira Dela Torre EP)

Moira is the first extended play (EP) by Filipina singer Moira Dela Torre. The EP is self-titled and consists of six tracks, all songs were originally written by Moira Dela Torre herself.

## Background

After joining the first season of The Voice of the Philippines, Dela Torre has kept her music career on track by working on corporate jingles and theme songs: including McDonald's "Hooray for Today", Surf's "Pinalaki", and Johnson & Johnson's "Signature of Love". In 2014, Dela Torre caught the attention of Ivory Music and offered her a recording contract for her self-titled debut EP, Moira.

## Track listing

6 songs were written by Dela Torre.
# Zarija Popović

Zarija R. Popović (Gjilan, 5 February 1856 - Belgrade, August 1934) was a Serbian national and educational worker, writer and head of State Statistics.
In 1870, Popović entered the oldest educational institution in the Belgrade the Saint Sava Seminary, founded in 1808 by the then minister of education Dositej Obradović. He was an excellent theology student, the first among his peers, and in the last year, he has ordained as a celibate priest by Metropolitan Mihailo, who recognized Zarija's natural acuity and intelligence for the teaching profession.
He first taught in his home town of Gjilan from 1874 to 1878 when he welcomed the victorious Serbian army. After the armed forces left Giljan, Popović went with the Serbian army to quell the attacks on the Serbs during the Serbian-Ottoman War in Vranje, where he remained as a teacher, and then as an administrative clerk at the Serbian Orthodox Diocese of Vranje. He was later twice appointed bishop by the Serbian Orthodox Church, to the Metropolitanate of Skopje and the Diocese of Prizren, but both times refused to accept the challenge, preferring to continue teaching instead.
In 1887, he was transferred to Belgrade and the Ministry of Education and the Public Relations Department for Education in Old Serbia and Macedonia. Two years later, when the department was added to the Ministry of Foreign Affairs, Zarija Popović started working at the Светосавсокој вечерњој школи/Svetosavsokoj večernjoj školi, the Saint Sava Evening School until 1912.
Popović wrote several interesting books recalling his time in Old Serbia.

## Works

* Pred Kosovom
* Pripovedke iz Stare Srbije
# Q'ara Qullu (disambiguation)

Q'ara Qullu (Aymara q'ara bare, bald, qullu mountain, "bare mountain", also spelled Cara Kkollu, Caracollo, Khara Khollu, Khara Kkollu) may refer to:
* Caracollo, a town in Bolivia
* Q'ara Qullu, a mountain in the Achacachi Municipality, Omasuyos Province, La Paz Department, Bolivia
* Q'ara Qullu (Ancoraimes), a mountain in the Achacachi Municipality, Omasuyos Province, La Paz Department, Bolivia
* Q'ara Qullu (Loayza), a mountain the Loayza Province, La Paz Department, Bolivia
* Q'ara Qullu (Sajama), a mountain the Sajama Province, Oruro Department, Bolivia
# Lyons Township, Mills County, Iowa

Lyons Township is a township in Mills County, Iowa, United States.

## History

Lyons Township was organized in 1857.
# Yativṛṣabha

Yativṛṣabha (Yativrishabha), also known as Jadivasaha, was a mathematician and Jain monk. He is believed to have lived during the 6th century, probably during 500–570. He studied under Arya Manksu and Nagahastin. He lived and worked between the periods of two great Indian mathematicians, Aryabhata (476 – 550) and Brahmagupta (598-668).

## Works

He compiled many works in Prakrit expounding Jain traditions. One of these, the Tiloyapannatti — a description of the universe and its parts, is of some importance to historians of Indian science because it incorporates formulas representative of developments in Jain mathematics between the older canonical works and the later texts of the ninth and following centuries. He wrote the book named Tiloyapannatti which describes cosmology from the point of view of Jain religion and philosophy. "The work also gives various units for measuring distances and time." Tiloya Panatti postulated different concepts about infinity. His work also describes the construction of the Universe expressed in specific numbers; for example, the diameter of the circular Jambu continent, upon which India is located, is 100,000 yojanas and its circumference is 316,227 yojanas, 3 krośas, 128 daṇḍas, 13 aṅgulas, 5 yavas, 1 yūkā, 1 ṛikṣā, 6 karmabhūmivālagras, 7 madhyabhogabhūmivālagras, 5 uttamabhogabhūmivālagras, 1 rathareṇu, 3 trasareṇus, 2 sannāsannas, and 3 avasannāsannas, plus a remainder of 23213/105409.
# MVCML

Multiple-valued current mode logic (MVCML) or current mode multiple-valued logic (CM-MVL) is a method of representing electronic logic levels in analog CMOS circuits. In MVCML, logic levels are represented by multiples of a base current, I$_{base}$, set to a certain value, x. Thus, level 0 is associated with the value of null, level 1 is associated with I$_{base}$ = x, level 2 is represented by I$_{base}$ = 2x, and so on.
# Scotch doubles (curling)

Scotch doubles is a type of curling played with two players per team and six stones per end per team. Three stones are delivered by each player, with six ends per game. Sweeping is permitted only after the far hog-line. Until two stones have been played (one from each side), stones in the free guard zone (those stones left in the area between the hog and tee lines, excluding the house) may not be removed by an opponent's stone.
# Vanavälja

Vanavälja may refer to several places in Estonia:
* Vanavälja, Jõgeva County, village in Jõgeva Parish, Jõgeva County
* Vanavälja, Viljandi County, village in Viljandi Parish, Viljandi County
# Maureen Francisco

Maureen Francisco is the executive producer of NW Productions, a media company that produces live shows and red carpet events. She is known for her role on the reality show Solitary 3.0.

## Personal life

Maureen Francisco came from humble beginnings. She was born in Manila, Philippines. She moved to the United States with her family at the age of 5. She attended Pacific Lutheran University and received a bachelor's degree in Journalism in 1999.

## Career

After she graduated, she went on to be a TV reporter around the US. In 2007, she was the first contestant on CBS's Power of 10, hosted by Drew Carey. Then in 2009, Maureen was contestant #5 on Fox Reality Channel's Solitary 3.0, where she finished in sixth place.
Today, Maureen is the executive producer of NW Productions and published author of It Takes Moxie: Off the Boat, Out of School, To Making It Your Way in America. She is also the co-founder of Beauty | Brand | Believe Expo, a confidence building workshop and The Global Beauty Awards Show that celebrates the pageant community (all systems) at the international level.
# Maughan (surname)

Maughan is a surname. Notable people with the surname include:
* Ariel Maughan (1923–1997), American professional basketball player
* Arthur Maughan, American wrestler
* Bridget Atkinson (née Maughan) (1732–1814) English farmer and shell collector who amassed a collection from around the world. First honorary member of the Society of Antiquaries of Newcastle upon Tyne.
* Clyde Maughan, American engineer
* Cynthia Maughan (born 1949), American video artist
* Deryck Maughan (born 1947), British businessman and philanthropist
* George Maughan (1910–2003), Canadian boxer who competed in the 1932 Summer Olympics
* James Maughan (1826–1871), Methodist minister in Adelaide, South Australia, father of Milton Moss Maughan
* John Maughan Barnett (1867–1938), New Zealand organist, choirmaster, pianist, composer and conductor
* Margaret Maughan (1928–2020), British Paralympic archer
* Milton Moss Maughan (1856–1921), South Australian educationalist, son of James Maughan
* Monica Maughan (1933–2010), Australian actor with roles in film, theatre, radio and television
* Noel Maughan, Australian politician, Nationals member for Rodney in the Victorian Legislative Assembly 1989–2006
* Peter Maughan (1811–1871), early Mormon pioneer who settled the Cache Valley of Utah under the direction of Brigham Young
* Rex Maughan, the founder, president, and CEO of Forever Living Products and Terry Labs
* Russell Maughan, pioneer aviator and U.S. military pilot
* Sharon Maughan (born 1950), British actress
* Susan Maughan (born 1938), English singer who released successful singles in the 1960s
* William Maughan (footballer) (1894–1916), English footballer
* William Ryott Maughan (1863–1933), English-born Australian politician
# Maum

An Mám (anglicized as Maum, or sometimes Maam) is a small Gaeltacht village and its surrounding lands in Connemara, County Galway, Ireland.

## Name

An Mám is Irish for "the pass" and as this is a Gaeltacht (principally Irish-speaking) area, the area's name formally exists only in Irish - the anglicised form has no official standing, although it has been in use for centuries, too.

## Location and access

The village is located at the southern end of the Maam Valley, where it comes to Lough Corrib; the other end lies at Leenaun on Killary Harbour. The settlement lies at an altitude of around 20 metres, between where the main river of the southern two thirds of the valley, Joyce's River, is captured by the larger Abhainn Béal Átha na mBreac (Bealnabrack River) and where the Failmore River joins that river's mouth at the northern end of the lake. It sits at the edge of a mountainous area, the principal part of which forms the Maumturk or Maamturk Mountains.
An Mám lies north of Maam Cross, an important crossroads from which the main road serving the settlement, and providing a secondary route through the Maam Valley to Leenaun, the R336, comes, splitting off from the R59 Galway to Clifden road. Maam Bridge, built in 1823, takes the R336 across the Bealnabrack River.

## History

This area formed part of the wider Joyce Country, named for a key family grouping, the Joy family, originally from Wales, which dominated the region for centuries.

## Features

Historically there was a castle in the area, and from the 19th century, a small courthouse (closed in 2004) and a post office. Alexander Nimmo built an inn in 1820 at the eastern end of Maam Bridge, and this later became the Maum Hotel, owned by the family of Lord Leitrim for many years; it now operates as Keane's Pub.
The area has several B&B establishments, and there is a hotel complex and service station at Maam Cross. Many community facilities are provided from Leenaun. There is free fishing in the river and the nearer parts of the lake, and a jetty was built by Maam Bridge to facilitate angling access.
# Maurice O'Shea

Maurice O'Shea may refer to:
* Maurice O'Shea (hurler)
* Maurice O'Shea (winemaker)
# Maurice O'Shea (hurler)

Maurice O'Shea (27 December 1879 – 14 August 1911) was an Irish hurler who played as a forward with the Cork senior hurling team. He was an All-Ireland Championship winner in 1902.

## Career

O'Shea began his hurling career at club level with Dungourney in East Cork. He played at a time when the club enjoyed its most successful era ever and won Cork Senior Championship titles in 1902, 1907 and 1909.
At inter-county level, O'Shea first played for the Cork senior hurling team on 9 August 1903 in what was the delayed 1902 championship. After missing Cork's Munster Championship triumph, he later won an All-Ireland Championship medal after a 3-13 to no score defeat of London at the Cork Athletic Grounds. O'Shea later lined with Cork on a number of occasions before playing his last game on 29 August 1909.
O'Shea died in a drowning accident at Lough Carrig Bay in Cork Harbour on 14 August 1911.

## Honours
### Dungourney

* Cork Senior Hurling Championship (3): 1902, 1907, 1909

### Cork

* All-Ireland Senior Hurling Championship (1): 1902
# Mavjuda Hakimova

Mavjuda Hakimova (5 May 1932 – 1993) was a Soviet-Tajikistani poet and playwright. She is sometimes known by the mononym Mavjuda.

## Life

Born into a family of workers in Khujand, then called Leninabad, Hakimova graduated from the Tajikistan State University in Dushanbe in 1958 and began working as an editor for numerous journals, including Pioneri Tojikiston (Pioneer of Tajikistan), Komsomoli Tojikiston (Komsomol of Tajikistan), Maš'al (Torch), and Zanoni Tojikiston (Women of Tajikistan). She joined the Communist Party of the Soviet Union in 1962. Her first poems appeared in 1951; with the publication of her first collection, Surudi sahar (Sunrise Song) in 1964, she gained much acclaim, and won a place in the Union of Soviet Writers in 1965. Much of her work combines the conventions of Persian poetry with standard Soviet ideas, and deals with the themes of love and nature. In the 1970s Hakimova turned to writing plays, depicting daily life in Tajikistan in the post-Stalin era. She also wrote two volumes of poetry for children. Hakimova was much awarded during her career; among the decorations which she received from the Soviet government were the Order of the Badge of Honour, the Order of Friendship of Peoples, and the Jubilee Medal "In Commemoration of the 100th Anniversary of the Birth of Vladimir Ilyich Lenin". Hakimova died in Khujand in 1993.

## Works

Source:

### In Tajik

* Surudi sahar, 1964
* Mavjuda Hakimova, Dushanbe, 1970 (in the "Ilhom" series)
* Mošinai mošinsavor, 1972
* ''Zistan meḵohad, 1973
* Afsonai solinavī, Dushanbe, 1973
* Habiba, Dushanbe, 1973
* Soyai gunoh, 1974
* Intizorī, 1975
* Yak qatra oftob, Tashkent, 1975
* ''Ba sūi nur, 1976
* Nabzi roh, Dushanbe, 1977
* Bačahoi guldast, 1978
* Zafar, Dushanbe, 1979
* Tūi bahor, Dushanbe, 1980
* ''Daryoi mehr, 1982
* Šaršara, Dushanbe, 1982
* Maro naḡz mebined? Še'rhoi bačagona, Dushanbe, 2008

### In Russian

* Dalëkiĭ put' k svetu. Stikhi i poèma, tr. R. F. Kazakova, Moscow, 1974.
* Kto krasivyĭ. Stikhi, tr. M. Khakimova, Moscow, 1982.
* Reka lyubvi. Stikhi, tr. V. Savel'ev, Moscow, 1987.
* Blagodarenie. Stikhi i poèmy, tr. R. F. Kazakova and V. Savel'ev, Dushanbe, 1988

### Studies

* S. Davronov, "Mavjuda," in Èntsiklopediyai adabiët va san'ati tojik II, ed. A. Q. Qurbonov et al., Dushanbe, 1989, p. 123.
* Mirzā Mollā-Aḥmadov, Ḵubān-e Pārsigu: bānovān-e soḵansarā-ye tājik, Tehran, 2003.
* Pisateli Tadzhikistana, Dushanbe, 1986, pp. 444–46.
* Usmon Tojī, Šoirahoi boiste'dod, Dushanbe, 1962.
# Mavuzi Hydroelectric Power Station

The Mavuzi Hydroelectric Power Station is an operational 41 megawatts (55,000 hp) hydroelectric power project in Mozambique. The power plant, first established in 1957, underwent upgrades and rehabilitation in 2017, adjusting its generating capacity, from 52 megawatts to 41 megawatts, with prolongation of its lifespan by another thirty years.

## Location

The power station is located near the villages of Maria and Costina, in Manica Province, along the Revue River, downstream of the Chicamba Hydroelectric Power Station. This location is approximately 132 kilometres (82 mi), by road, south-east of the town of Manica, where the provincial capital is located. Costina is located about 64 kilometres (40 mi), by road, south of the city of Chimoio, the largest city in Manica Province. The geographical coordinates of Mavuzi HPP are: 19°31'34.0"S, 33°29'35.0"E (Latitude:-19.526111, Longitude:33.493056).

## Overview

Mavuzi Hydroelectric Power Station (41 megawatts), together with nearby Chicamba Hydroelectric Power Station (44 megawatts), both located in Manica Province, were intended to supply electricity to the provinces of Manica and neighboring Sofala, supplemented with power obtained from the Cahora Bassa Dam.
Due to their age; Mavuzi HPP was commissioned in 1957, and Chicamba HPP was established in 1968, many replacement parts are not available on the market anymore and maintenance was a challenge in the 21st century. For a period of 3.5 years, beginning in 2013 until February 2017, both stations underwent refurbishment and upgrades, with the contractor manufacturing new hardware to replace what could not purchased on the open market.

## Refurbishment and improvements

The refurbishment contract was awarded to a consortium comprising Rainpower, a Norwegian supplier of hydroelectricity generating hardware and Cegelec, a French engineering company. Other entities included Hydrokarst, a French company that socializes in underwater inspection and installations.

## Construction costs

The rehabilitation bill in 2017 for both and Mavuzi HPP and Chicamba HPP is quoted as US$120 million (€90 million at that time). The sources of funding are illustrated in the table below:
Funding Sources for Mavuzi and Chicamba Hydroelectric Power Plants Rehabilitation :
| Rank | Funder | Amount in Euros | US $ Equivalent | Percentage | Notes |
| 1 | Swedish International Development Cooperation Agency | 30.00 million | 40.0 million | 33.3 | Loan |
| 2 | KfW | 15.8 million | 21.2 million | 17.6 | Loan |
| 3 | Agence Française de Développement (AFD) | 44.2 million | 58.8 million | 49.1 | Loan |
| | All | 90 million | 120 million | 100.00 | Total |
# Maulawi Dadullah

Maulawi Dadullah may refer to:
* Maulawi Dadullah (c. 1966–2007), Afghan Taliban leader
* Maulawi Dadullah (Pakistani Taliban) (c. 1965–2012), Pakistani Taliban leader
# Maximilian Herregouts

Maximilian Herregouts (fl. 1674) was a painter from the artist family Herregouts.
Maximilian Herregouts was born in Roermond, Limburg, present-day Netherlands (then Spanish Netherlands). He was the son of David Herregouts and Cecilia Genits. He was thus a brother of fellow painters Hendrik I, Guillaume and Jan Baptist Herregouts. His sister Elisabeth married Mechelen painter Gillis Smeyers.
Two works by Herregouts are known, one entitled Kitchen, in which a woman is busy baking pancakes (1674), dated and signed with his name, and a second entitled Eliezer and Rebecca at the well.
# Maurizio Sciarra

Maurizio Sciarra (born 15 April 1955) is an Italian film director.

## Awards

He was awarded the Golden Leopard at the 2001 Locarno International Film Festival for Off to the Revolution by a 2CV
# Maykor

MAYKOR is a Russian company and provider of IT and business process outsourcing services. It was founded in 2010 and is headquartered in Moscow, Russia. The company's main business areas include support services for: IT infrastructure; business applications; Telecommunication, Retail, banking, oil and gas, and transportation and logistics equipment; facility management; as well as business process outsourcing. The company has 83 branches and more than 400 service units in Russia.
The employee headcount as of 2015 is more than 5,200

## History

The company was founded in 2010. From the beginning, the company had specialized in IT outsourcing services and facility management. In 2012, MAYKOR embarked on a mergers and acquisitions strategy that resulted in regional expansion. The company built its wholly owned network of 83 branches and 400 service subdivisions across Russia and developed new business lines in business application support services and industry specific services for banking, retail, gas and oil, and transportation and logistics.
In 2012, MAYKOR joined the Russian Association of Strategic Outsourcing, ASTRA, and the International Association of Outsourcing Professionals (IAOP). The company is co-chair of IAOP's Russia Chapter.
In June 2013, MAYKOR completed acquisition of GMCS, a provider of business management information systems development services.
In August 2013, the Russian Direct Investment Fund, the European Bank for Reconstruction and Development, and the CapMan Russia II Fund signed an agreement to invest $100 million in MAYKOR. The RDIF, Russia's state owned investment fund, had committed $50 million, while EBRD and CapMan planned an investment of $25 million each over a 12-month period.
In August 2014, MAYKOR completed acquisition of the ВТЕ Group of Companies. With this acquisition, MAYKOR's banking equipment servicing resources were combined with BTE's assets to form a new subsidiary. MAYKOR now owns 74,99% of BTE.

## Management

MAYKOR is headed by its president, Sergey Sulgin.

## Awards and achievements

The International Association of Outsourcing Professionals (IAOP) has named MAYKOR to the top-ranked Leaders Category of The Global Outsourcing 100 in February 2014. The company received this recognition again in 2015. MAYKOR was also recognized as one of the top ten providers in the EMEA region in the 2Q 2015 ISG Outsourcing Index. At the end of 2014, the company was ranked as one of the leaders in IT services by the Russian business magazine "Kommersant-Dengi", as well as by Russian rating agencies RAEX and RIA Rating.
# McCrostie

McCrostie is a surname. Notable people with the surname include:
* John McCrostie (born c. 1970), American politician
* Lauren McCrostie (born 1996), English actress