OpenLLM-France/wikimedia huggingface dataset:
# Rab geranylgeranyltransferase

Rab geranylgeranyltransferase also known as (protein) geranylgeranyltransferase II is one of the three prenyltransferases. It transfers (usually) two geranylgeranyl groups to the cystein(s) at the C-terminus of Rab proteins.
    geranylgeranyl diphosphate + protein-cysteine $\rightleftharpoons$ S-geranylgeranyl-Cys-protein + diphosphate
The C-terminus of Rab proteins varies in length and sequence and is referred to as hypervariable. Thus Rab proteins do not have a consensus sequence, such as the CAAX box, which the Rab geranylgeranyltransferase can recognise. Instead Rab proteins are bound by the Rab escort protein (REP) over a more conserved region of the Rab protein and then presented to the Rab geranylgeranyltransferase.
Once Rab proteins are prenylated, the lipid anchor(s) ensure that Rabs are no longer soluble. REP therefore plays an important role in binding and solubilising the geranylgeranyl groups and delivers the Rab protein to the relevant cell membrane.

## Reaction

Rab geranylgeranyltransferase (RabGGTase; enzyme commission code EC 2.5.1.60) is classified as a transferase enzyme; specifically, it is in the protein prenyltransferase family along with two other enzymes (protein farnesyltransferase and protein geranylgeranyltransferase type-I). The reaction catalyzed by RabGGTase is summarized as follows:
* geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate
This reaction is essential in the control of membrane docking and fusion. Studies of mice have shown that Rab GGTase genes are expressed in all major adult organs, as well as in some embryonic units, including the spinal cord and liver (Chinpaisal).
Rab geranylgeranyltransferase’s “outsourcing” of specificity (using REP to interact with the Rab proteins it prenylates, as mentioned above) is unique among prenyltransferases. Rab GGTase is “responsible for the largest number of individual protein prenylation events in the cell,” probably due to this ability to interact with many different Rab proteins (it can prenylate any sequence containing a cysteine residue).
In vitro studies have shown that Rab GGTase can be inhibited by nitrogen-containing bisphosphonate drugs such as risedronate; however, the effects of such drugs seem to be much more limited in vivo (Coxon).

## Structure

RabGGTase is a heterodimer composed of alpha and beta subunits that are encoded by the RABGGTA and RABGGTB genes, respectively. The structure of rat RabGGTase has been determined by X-ray diffraction (see image to the left) to a resolution of 1.80 Å. RabGGTase’s secondary structure is largely composed of alpha helices; the alpha subunit is 74% helical with no beta sheets, while the beta subunit is 51% helical and 5% beta sheet. There are 28 alpha helices total (15 in the alpha subunit and 13 in the beta subunit) and 15 very short (no more than 4 residues) beta sheets. Functional RabGGTase binds three metal ions as ligands: two calcium ions (Ca$^{2+}$) and a zinc ion (Zn$^{2+}$), all of which interact with the beta subunit.
# Rab Wilson

Rab Wilson (born 1 September 1960, in New Cumnock, Ayrshire) is a Scottish poet who writes mainly in the Scots language. His works include a Scots translation of the Rubaiyat of Omar Khayyam, and the poetry books Accent o the Mind, Life Sentence, and A Map for the Blind.

## Life

He held an engineering apprenticeship with the National Coal Board, working at Barony Pit in Ayrshire, but gave up mining as a result of the UK miners' strike (1984–1985) and instead trained as a psychiatric nurse.
As well as poetry, he has also campaigned on health issues, for the rights of health workers to speak openly about their concerns and act as whistleblowers.
In 2012 he spoke to lawyers at the 4th European Collaborative Conference.
He is closely connected with Scottish national poet Robert Burns, who was also from Ayrshire. Wilson worked on the project Burnsiana with Calum Colvin and discovered that Burns may have taken part of Tam O' Shanter from English poet Edmund Bolton.
In 2013 he was selected as the first James Hogg Creative Resident, living and writing in Ettrick Valley, home of the poet and writer James Hogg.
He won the 2008 McCash Scots poetry competition.
In 2009 he jokingly threatened to behead Conservative politician Kenneth Baker while giving the address to the haggis at the Wordsworth Trust Book Festival Burns Night.

## Works
### The Ruba'iyat of Omar Khayyam

His free translation of The Ruba'iyat of Omar Khayyam was published in 2010.

### The Jolly Beggars

Wilson adapted Robert Burns' The Jolly Beggars for the stage. It was a runner-up for the 2007 McLellan Award for Play Writing.

### Ye're There Horace!

Ye're There Horace! was an art book based on the Roman satirist Horace, made in conjunction with artist Hugh Bryden.

### Burnsiana

Burnsiana is a collaboration with artist Calum Colvin, producing an art exhibition and book featuring poems written by Wilson in response to the work of Robert Burns. Colvin produced artworks by painting Burns-related images onto rooms full of objects.

### Other poetry

His other works include the 15-sonnet sequence 1957 Flying Scot, a tribute to a Scottish bicycle manufacturer's marque, Flying Scot. The sequence has been performed as far afield as Brooklyn.
# Heroes (book series)

Heroes is a series of short novels and plays intended for young boys, created with series editor Frank Cottrell Boyce. The series includes teaching resources and is designed to motivate reluctant readers.
The series comprises three novels and one play intended for use in Year 7, and three novels and one play intended for use in Year 8, as part of Key Stage 3 . Each novel and play is also accompanied by an "ActiveTeach" CD-ROM providing interactive learning opportunities linked to the source material. There is also a Teacher Guidebook, Improve Boys' Reading.

## Books
### For Year 7 teaching

* Eg and Me (by David Grant)
* Ghost Game (by Nigel Hinton)
* i-ssassins (by Christopher Edge)

### For Year 8 teaching

* Blood Oath (by Chris Priestley)
* Do Not Wake the Devil (by A&P Peters)
* Monster Island (by Justin Richards)

## Plays
### For Year 7 teaching

* The Death of Jude Hill (by Richard Conlon)

### For Year 8 teaching

* Chamber of Nothing (by Cathy Forde)
# José Contreras (disambiguation)

José Contreras (born 1971) is a Cuban Major League Baseball pitcher.
José Contreras may also refer to:
* José Castellanos Contreras (1893–1977), Salvadoran military officer and diplomat who rescued Jews during the Holocaust
* José Alirio Contreras (born 1978), Venezuelan cyclist
* José Contreras (footballer, born 1982), Chilean football right-back
* José Manuel Contreras (born 1986), Guatemalan football midfielder
* José Contreras (footballer, born 1994), Venezuelan football goalkeeper
* José Miguel Contreras, Canadian rock singer and guitarist of By Divine Right
# Brody, Końskie County

Brody is a village in the administrative district of Gmina Końskie, within Końskie County, Świętokrzyskie Voivodeship, in south-central Poland. It lies approximately 6 kilometres (4 mi) south-west of Końskie and 36 km (22 mi) north-west of the regional capital Kielce.
# Marti Barris

Marti Barris (April 6, 1937 – December 13, 1995) was an American actress and popular singer. She recorded for Keen Records during the late 1950s and early 1960s, but never had a big hit. She was the daughter of Harry Barris and Loyce Whiteman, both musicians.
Baris graduated from Burbank High School. When she was 19, she signed with Verve Records. She was the first female vocalist to sing with Freddy Martin's orchestra. In 1960, she began playing Peppi Mint on the Howdy Doody television program.

## Discography

* "Can't You Read Between the Lines"/"Ahbe Casabe"-Keen 4018
* "You're My Thrill"/"Sweet Talk"-Keen 1959
# SS Patrick H. Morrissey

SS Patrick H. Morrissey was a Liberty ship built in the United States during World War II. She was originally named after Patrick H. Morrissey, a former head of the Brotherhood of Railway Trainmen. She was transferred to the British Ministry of War Transportation (MoWT) and renamed Samdee upon completion.

## Construction

Patrick H. Morrissey was laid down on 23 October 1943, under a Maritime Commission (MARCOM) contract, MC hull 1507, by J.A. Jones Construction, Brunswick, Georgia; she was sponsored by Katherine M. Geraghty, daughter of Patrick H. Morrissey, and launched on 9 December 1943.

## History

She was allocated to Thos. & Jno. Brocklebank, Ltd., on 17 December 1943. On or about 18 April 1947, she was sold to Thos. & Jno. Brocklebank, Ltd. Samdee was scrapped in 1967.
# Rosières-sur-Barbèche

Rosières-sur-Barbèche (French pronunciation:) is a commune in the Doubs département in the Bourgogne-Franche-Comté region in eastern France.

## Geography

The commune lies 15 km (9.3 mi) southwest of Pont-de-Roide.
# Heyden's gecko

Heyden's gecko (Hemidactylus robustus) is a species of geckos, family Gekkonidae, found in northeastern Africa and in the Middle East.

## Distribution

It may be found in Egypt, Sudan, Eritrea, Ethiopia, Somalia, Kenya, Yemen, Oman, Qatar, Iraq, Iran, Saudi Arabia, the United Arab Emirates and Pakistan.

## Conservation status

In Egypt, it is expected to lose much of its currently suitable distribution in the future due to anthropogenic climate change.

## Original publication

* Heyden, 1827 : Atlas zu der Reise im nördlichen Afrika. I. Zoologie. Reptilien. H. L. Brönner, p. 1-24 (integrated text).
# S/2019 S 19

S/2019 S 19 is a natural satellite of Saturn. Its discovery was announced by Edward Ashton and Brett J. Gladman on May 15, 2023 from observations taken between July 3, 2019 and July 8, 2021.
S/2019 S 19 is about 3 kilometers in diameter, and orbits Saturn at a distance of 23.472 Gm in 1,342.57 days, at an inclination of 146.8, orbits in retrograde direction and eccentricity of 0.372. S/2019 S 19 belongs to the Norse group and its inclination is similar to Bestla and Narvi.
# SAP BI Accelerator

In computing, the SAP BW Accelerator is a computer appliance - preinstalled software on predefined hardware - which is used to speed up OLAP queries. The software was initially known as the BI Accelerator.
SAP BW Accelerator includes indexes that are vertically inverted reproductions of all the data included in InfoCubes (i.e., fact and dimension tables as well as master data). Note that there is no relational or other database management systems in BW Accelerator. There is only a file system, and indexes are essentially held as flat files. The second primary component of SAP BW Accelerator is the engine that processes the queries in memory - it uses the SAP TREX search engine. The software is running on an expandable rack of blade servers. The operating system used for BW Accelerator is 64-bit SUSE Linux Enterprise Server (SLES).

## Hardware partners

The software is optimized for specific hardware and operating system combinations.
The list of partners which deliver the appliance is:
* IBM BW Accelerator solution
* HP
* Fujitsu Siemens Computers
* Sun BI Accelerator Offering
# S.K. Roeselare

Sportkring Roeselare, abbreviated to SK Roeselare, also known in French as SK Roulers, is a Belgian football club from the city of Roeselare in West Flanders. The club currently play in Belgian Division 2, the fourth tier of Belgian football. Its matricule is 8264 and club has black and white as club colours.

## History

In 1975, VK Dadizele joined the Belgian FA, receiving matricule 8264. The club never left the Belgian Provincial Leagues, but almost gained promotion to the national level in 2019 via the promotion playoffs.
In 2021, the club merged with K.S.V. Roeselare, which had just gone bankrupt while playing in the Belgian National Division 1 (third level). The club continued as SK Roeselare-Daisel using the matricule of VK Dadizele and continuing from the level of Dadizele (at that time the sixth level (First Provincial Division West-Flanders)). In its first season, the club was immediately promoted to the national leagues after finishing second.
In 2023, the name was changed to SK Roeselare and at the end of the season after finishing 4th, the club promoted to Belgian Division 2 via end of season promotion playoffs.
# Herold Georg Wilhelm Johannes Schweickerdt

Herold Georg Wilhelm Johannes Schweickerdt (28 February 1903, Schmie, Baden-Württemberg – 21 February 1977, Pretoria) was a German botanist.
In 1904 he moved with his parents to Pretoria, where he later studied at Transvaal University. From 1922 to 1924 he was a student at the University of Bonn (1922–24), later becoming a professor in Pretoria. From 1940 to 1964 he served as inspector of the Botanical Garden at the University of Göttingen.
During his career he collected plants in Transvaal, South-West Africa, Rhodesia, Mozambique and Natal. The plant species Gasteria schweickerdtiana is named after him.
The H.G.W.J Schweickerdt Herbarium (PRU) at the University of Pretoria is named in his honour.

## Publications

* Untersuchungen über Photodinese bei Vallisneria spiralis, 1928 - Studies on photodinese in Vallisneria spiralis.
# Heroldishausen

Heroldishausen is a village and a former municipality in the Unstrut-Hainich-Kreis district of Thuringia, Germany. Since 1 January 2019, it is part of the municipality Unstrut-Hainich.
# Herold J. Weiler

Herold J. Weiler (April 12, 1886 – November 18, 1945) was a United States Army officer who served as acting Chief of the National Guard Bureau.

## Early life

Herold James Weiler was born in Tioga, Illinois on April 12, 1886. He was raised and educated in Corsicana, Texas, and enlisted in the Texas National Guard's, Troop D, 1st Cavalry Squadron in 1907.
Weiler rose through the ranks and was a First Sergeant when he was commissioned as a First Lieutenant in 1912.
In his civilian career Weiler was the owner and operator of Weiler Manufacturing, makers of heavy duty overalls, pants, and other outdoor wear for oil field and oil rig workers. In the 1920s he also worked in other management positions within the oil industry.
Weiler served on the Mexican border during the Pancho Villa Expedition in 1916 as a member of Troop D.

## World War I

During World War I Weiler served in France as a member of the 131st Field Artillery Regiment, a unit of the 36th Infantry Division.

## Post World War I

After World War I, Weiler continued his military service, including command of 2nd Battalion, 131st Field Artillery as a Major.
Weiler was a Lieutenant Colonel when he graduated from the United States Army Command and General Staff College in 1929.

## National Guard Bureau

In the early 1930s, Weiler was assigned to full-time National Guard duty with the Militia Bureau (now National Guard Bureau), serving as Chief of the Personnel Division.
Weiler was acting Chief of the Militia Bureau (now Chief of the National Guard Bureau) from December, 1935 to January, 1936.

## Return to Texas

In 1935, Weiler returned to Texas as commander of the 131st Field Artillery Regiment and U.S. Property and Disbursing Officer for Texas.
Weiler graduated from Washington College of Law in 1936 and passed the bar in Texas and Washington, D.C.

## World War II

During World War II Weiler served as procurement officer for the Texas Selective Service Department. He was approaching the mandatory retirement age of 60 and was on terminal leave at the time of his death.

## Death and burial

Weiler died in Refugio, Texas on November 18, 1945. He was killed in an accident while hunting, when a motorist drove through a field and crashed his car into Weiler's duck blind. Weiler was buried at Oakwood Cemetery in Corsicana.
# Hideaway Beach

Hideaway Beach, also known as Pali Ke Kua Beach, is a small, secluded beach located on the north shore of Kauai. It sits under the cliffs of Princeville. The beach is small and secluded, with white sand and clear waters. The water is typically calm and protected from the wind, making it a great place for swimming and snorkeling.

## Overview

The coral reefs offshore are home to a variety of colorful fish and sea creatures. The beach itself is stunning, offering clean white sand, breezy shade from the trees, and excellent swimming and snorkeling when the surf is low. The underwater world here is teeming with marine life, including colorful tropical fish, sea turtles, and various coral species. Snorkelers and divers can explore the vibrant reef systems just offshore, making it a popular spot for underwater enthusiasts.

## Geography

The coordinates of the beach in degrees-minutes-seconds format are 22°13′24″N 159°29′44″W﻿ / ﻿22.22333°N 159.49556°W﻿ / 22.22333; -159.49556.
Address: Hideaway Beach, Princeville, HI 96722, United States
# Hideaki Kobayashi

Hideaki Kobayashi may refer to:
* Hideaki Kobayashi (composer) (born 1973), game music composer for Sega
* Hideaki Kobayashi (diplomat) (born 1945), Japanese diplomat
# SCAT-I

SCAT-I (Special CATegory I) is an instrument landing system for aircraft, based on Differential GPS. It is developed under project management by Avinor, the Norwegian airport administration. It is installed on several short runway airports for domestic operation in Norway. It requires special equipment to be installed in the aircraft, and allows precision landings in bad visibility, something that is important on short runways where bad weather including snow storms are common. The system was operational for the first time in 2007, first installed at Brønnøysund, then at several other airports. As of 2013 it is installed at 21 regional airports in Norway.
# Hesse Peak

Hesse Peak (54°2′S 38°0′W﻿ / ﻿54.033°S 38.000°W﻿ / -54.033; -38.000) is, at 515 metres (1,690 ft), the highest peak on Paryadin Ridge, lying midway between Cape Alexandra and Cape Paryadin at the west end of South Georgia. It was charted and named by a German expedition under Kohl-Larsen in 1928–29.
# Hesse pencil

In mathematics, the syzygetic pencil or Hesse pencil, named for Otto Hesse, is a pencil (one-dimensional family) of cubic plane elliptic curves in the complex projective plane, defined by the equation
    $\lambda (x^{3}+y^{3}+z^{3})+\mu xyz=0.$
Each curve in the family is determined by a pair of parameter values ($\lambda ,\mu$) (not both zero) and consists of the points in the plane whose homogeneous coordinates $(x,y,z)$ satisfy the equation for those parameters. Multiplying both $\lambda$ and $\mu$ by the same scalar does not change the curve, so there is only one degree of freedom in selecting a curve from the pencil, but the two-parameter form given above allows either $\lambda$ or $\mu$ (but not both) to be set to zero.
Each curve in the pencil passes through the nine points of the complex projective plane whose homogeneous coordinates are some permutation of 0, –1, and a cube root of unity. There are three roots of unity, and six permutations per root, giving 18 choices for the homogeneous coordinates of each point, but they are equivalent in pairs giving only nine points. The family of cubics through these nine points forms the Hesse pencil. More generally, one can replace the complex numbers by any field containing a cube root of unity and define the Hesse pencil over this field to be the family of cubics through these nine points.
The nine common points of the Hesse pencil are the inflection points of each of the cubics in the pencil. Any line that passes through at least two of these nine points passes through exactly three of them; the nine points and twelve lines through triples of points form the Hesse configuration.
Every elliptic curve is birationally equivalent to a curve of the Hesse pencil; this is the Hessian form of an elliptic curve. However, the parameters ($\lambda ,\mu$) of the Hessian form may belong to an extension field of the field of definition of the original curve.
# SNF1LK2

Serine/threonine-protein kinase SIK2 is an enzyme that in humans is encoded by the SIK2 gene.

## Interactions

SNF1LK2 has been shown to interact with CRTC2.
# SHAZAM (interbank network)

SHAZAM is a United States–based interbank network and EFTPOS network headquartered in Johnston, Iowa that operates primarily in the Midwestern United States. The network was founded in 1976 and is a member-owned financial services and payments processing company.
SHAZAM is a single-source provider of debit cards, automated teller machines (ATMs), merchant, marketing, training, risk, fraud prevention and ACH Network services.
They are partnered with Presto!, a similar network covering the southeastern part of the US.
# Hicom

Hicom or HICOM may refer to:
* Hicom (telecommunication) [de], a PBX/ISDN telephone system family, including the Hicom 300, by Siemens
* HICOM (holding company) [de] (Heavy Industries Corporation of Malaysia) aka HICOM Holding Berhad
* HICOM Automotive Manufacturers (Malaysia)
* DRB-HICOM, a Malaysian company after the merger of DRB and HICOM
# Higashiibaraki District, Ibaraki

Higashiibaraki District (東茨城郡, Higashiibaraki-gun) is a district located in Ibaraki Prefecture, Japan.
As of 2003, the district has an estimated population of 122,478 and a density of 284 persons per km$^2$. The total area is 431.44 km$^2$.

## Towns and villages

* Ibaraki
* Ōarai
* Shirosato

## Mergers

* On October 16, 2004 the town of Ōmiya absorbed the villages of Miwa and Ogawa, all from Naka District; the town of Yamagata, and the village of Gozenyama, in order to turn the town into the current city of Hitachiōmiya.
* On February 1, 2005 the town of Jōhoku, and village of Katsura merged with the village of Nanakai, from Nishiibaraki District, to form the new town of Shirosato.
* Also on February 1, 2005 the town of Uchihara merged into the city of Mito.
* On March 20, 2006 the towns of Ogawa and Minori merged with the village of Tamari, from Niihari District, to form the new city of Omitama.
* On December 8, 2007 the town of Ibaraki was scheduled to merge into the city of Mito, but those plans were abandoned.