# List of leaders during the Byzantine Papacy

The Byzantine emperor, Pope of Rome, and Patriarch of Constantinople often came into conflict during the Byzantine Papacy (537–752). Rival claimants to either See or the throne often buttressed their authority by the endorsement of or attempted to depose other incumbents.
| Period | Pope | Emperor | Patriarch |
| 537–552 | Vigilius (537–555) | Justinian I (527–565) | Menas (536–552) |
| 552–555 | Vigilius (537–555) | Justinian I (527–565) | Eutychius (552–565) |
| 555–561 | Pegalius I (556–561) | Justinian I (527–565) | Eutychius (552–565) |
| 561–565 | John III (561–574) | Justinian I (527–565) | Eutychius (552–565) |
| 565–574 | John III (561–574) | Justin II (565–578) | John Scholasticus (565–577) |
| 574–577 | Benedict I (575–579) | Justin II (565–578) | John Scholasticus (565–577) |
| 577–578 | Benedict I (575–579) | Justin II (565–578) | Eutychius (577–582), restored |
| 578–579 | Benedict I (575–579) | Tiberius II Constantine (578–582) | Eutychius (577–582), restored |
| 579–582 | Pelagius II (579–590) | Tiberius II Constantine (578–582) | Eutychius (577–582), restored |
| 582–590 | Pelagius II (579–590) | Maurice (582–602) | John IV Nesteutes (582–595) |
| 590–596 | Gregory I (590–604) | Maurice (582–602) | John IV Nesteutes (582–595) |
| 596–602 | Gregory I (590–604) | Maurice (582–602) | Cyriacus II (596–606) |
| 602–604 | Gregory I (590–604) | Phocas (602–610) | Cyriacus II (596–606) |
| 604–607 | Sabinian (604–606) | Phocas (602–610) | Cyriacus II (596–606) |
| 607–608 | Boniface III (607) | Phocas (602–610) | Thomas I (607–610) |
| 608–610 | Boniface IV (608–615) | Phocas (602–610) | Thomas I (607–610) |
| 610–615 | Boniface IV (608–615) | Heraclius (610–641) | Sergius I (610–638) |
| 615–619 | Adeodatus I (615–618) | Heraclius (610–641) | Sergius I (610–638) |
| 619–625 | Boniface V (619–625) | Heraclius (610–641) | Sergius I (610–638) |
| 625–638 | Honorius I (625–638) | Heraclius (610–641) | Sergius I (610–638) |
| 638–640 | Interregnum | Heraclius (610–641) | Pyrrhus I (638–641) |
| 640 | Severinus (640) | Heraclius (610–641) | Pyrrhus I (638–641) |
| 640–641 | John IV (640–642) | Heraclius (610–641) | Pyrrhus I (638–641) |
| 641 | John IV (640–642) | Constantine III (Feb.-May 641) Heraklonas (Feb.-Sept. 641) co-ruler Constans II (641) | Pyrrhus I (638–641) |
| 641–642 | John IV (640–642) | Constans II, as sole ruler (641–668) | Paul II (641–653) |
| 642–649 | Theodore I (642–649) | Constans II, as sole ruler (641–668) | Paul II (641–653) |
| 649–654 | Martin I (649–653) | Constans II, as sole ruler (641–668) | Paul II (641–653) |
| 654–657 | Eugene I (654–657) | Constans II, as sole ruler (641–668) | Peter (654–666) |
| 657–667 | Vitalian (657–672) | Constans II, as sole ruler (641–668) | Peter (654–666) |
| 667–668 | Vitalian (657–672) | Constans II, as sole ruler (641–668) | Thomas II (667–669) |
| 668–669 | Vitalian (657–672) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | Thomas II (667–669) |
| 669–672 | Vitalian (657–672) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | John V (669–675) |
| 672–675 | Adeodatus II (672–676) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | John V (669–675) |
| 675–676 | Adeodatus II (672–676) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | Constantine I (675–677) |
| 676–677 | Donus (676–678) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | Constantine I (675–677) |
| 677–678 | Donus (676–678) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | Theodore I (677–679) |
| 678–679 | Agatho (678–681) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | Theodore I (677–679) |
| 679–682 | Agatho (678–681) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | George I (679–686) |
| 682–684 | Leo II (682–683) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | George I (679–686) |
| 684–685 | Benedict II (684–685) | Constantine IV (668–685) Mezezius, usurper (668) co-ruler Justinian II (681–685) | George I (679–686) |
| 685–686 | John V (685–686) | Justinian II, as sole ruler (685–695) | George I (679–686) |
| 686–687 | Conon (686–687) | Justinian II, as sole ruler (685–695) | Interregnum |
| 687–693 | Sergius I (687–701) Theodore (687) Paschal (687) | Justinian II, as sole ruler (685–695) | Paul III (687–693) |
| 693–695 | Sergius I (687–701) Theodore (687) Paschal (687) | Justinian II, as sole ruler (685–695) | Callinicus I (693–705) |
| 695–698 | Sergius I (687–701) Theodore (687) Paschal (687) | Leontios (695–698) | Callinicus I (693–705) |
| 698–701 | Sergius I (687–701) Theodore (687) Paschal (687) | Tiberios III (698–705) | Callinicus I (693–705) |
| 701–705 | John VI (701–705) | Tiberios III (698–705) | Callinicus I (693–705) |
| 705–708 | John VII (705–707) | Justinian II, restored (705–711) | Cyrus (705–711) |
| 708 | Sisinnius (708) | Justinian II, restored (705–711) | Cyrus (705–711) |
| 708–711 | Constantine (708–715) | Justinian II, restored (705–711) | Cyrus (705–711) |
| 711–712 | Constantine (708–715) | Philippikos (711–713) | Interregnum |
| 712–713 | Constantine (708–715) | Philippikos (711–713) | John VI (712–715) |
| 713–715 | Constantine (708–715) | Anastasios II (713–715) | John VI (712–715) |
| 715–717 | Gregory II (715–731) | Theodosios III (715–717) | Germanus I (715–730) |
| 717–730 | Gregory II (715–731) | Leo III the Isaurian (717–741) co-ruler Constantine V (720–741) | Germanus I (715–730) |
| 730–731 | Gregory II (715–731) | Leo III the Isaurian (717–741) co-ruler Constantine V (720–741) | Anastasius (730–754) |
| 731–741 | Gregory III (731–741) | Leo III the Isaurian (717–741) co-ruler Constantine V (720–741) | Anastasius (730–754) |
| 741–752 | Zachary (741–752) | Constantine V, as sole ruler (741–775) | Anastasius (730–754) |