# List of bus routes in Onondaga County, New York

The following routes are operated by CNYRTA's CNY Centro division, in and around the City of Syracuse and Onondaga, Cayuga, and Oswego counties.
| Base Route | Terminals | Terminals | Major streets | Areas & Landmarks served |
| 8 Syrculator | Centro Transit HUB | 8: W. Washington & S. Clinton Streets | Salina Street, Franklin Street, Washington Street, S. State Street, Harrison Street | Onondaga County Central Library, Clinton Square, Franklin Square, City Hall, City & County Government buildings, War Memorial, Everson Museum Free Downtown Syracuse circulator |
| 10 S. Salina St | Centro Transit HUB | 110: Valley Plaza | South Salina Street | One Centro Center, Upstate University Hospital, Valley Plaza, Clary Middle School, Green Hills Farms Shopping Center, Nedrow |
| 10 S. Salina St | Centro Transit HUB | 410: Conklin Ave | South Salina Street | One Centro Center, Upstate University Hospital, Valley Plaza, Clary Middle School, Green Hills Farms Shopping Center, Nedrow |
| 16 N. Salina St | Centro Transit HUB | 16: Regional Transportation Center & Destiny USA | North Salina Street, 1st North Street, Buckley Road, 7th North Street, Old Liverpool Road, Electronics Parkway | Little Italy, Regional Transportation Center, Destiny USA, Lockheed Martin, Liverpool |
| 16 N. Salina St | Centro Transit HUB | 116: 7th North Street | North Salina Street, 1st North Street, Buckley Road, 7th North Street, Old Liverpool Road, Electronics Parkway | Little Italy, Regional Transportation Center, Destiny USA, Lockheed Martin, Liverpool |
| 16 N. Salina St | Centro Transit HUB | 216: Electronics Parkway | North Salina Street, 1st North Street, Buckley Road, 7th North Street, Old Liverpool Road, Electronics Parkway | Little Italy, Regional Transportation Center, Destiny USA, Lockheed Martin, Liverpool |
| 16 N. Salina St | Centro Transit HUB | 316: Electronics Parkway via Old Liverpool Road | North Salina Street, 1st North Street, Buckley Road, 7th North Street, Old Liverpool Road, Electronics Parkway | Little Italy, Regional Transportation Center, Destiny USA, Lockheed Martin, Liverpool |
| 20 James St | Centro Transit HUB | 20: Eastwood – Lamson Street | James Street, Midler Avenue, Molloy Road | Bryant & Stratton College, Lincoln Middle School, Eastwood, Hancock Airpark |
| 20 James St | Centro Transit HUB | 120: Midler Ave | James Street, Midler Avenue, Molloy Road | Bryant & Stratton College, Lincoln Middle School, Eastwood, Hancock Airpark |
| 20 James St | Centro Transit HUB | 220: Hancock Airpark | James Street, Midler Avenue, Molloy Road | Bryant & Stratton College, Lincoln Middle School, Eastwood, Hancock Airpark |
| 21 James St - Sunnycrest | Centro Transit HUB | 21: Sunnycrest Road | James Street, Teall Avenue, Sunnycrest Road | Bryant & Stratton College, Lincoln Middle School, Henninger High School, Shop City, Eastwood |
| 21 James St - Sunnycrest | Centro Transit HUB | 121: Sunnycrest Road via Shop City | James Street, Teall Avenue, Sunnycrest Road | Bryant & Stratton College, Lincoln Middle School, Henninger High School, Shop City, Eastwood |
| 22 James St - Rt. 298 | Centro Transit HUB | 22: Rt. 298/Carrier Circle | James Street, Thompson Road, Fly Road | Bryant & Stratton College, Lincoln Middle School, Eastwood, Carrier Circle |
| 22 James St - Rt. 298 | Centro Transit HUB | 122: East Syracuse via Fly Road | James Street, Thompson Road, Fly Road | Bryant & Stratton College, Lincoln Middle School, Eastwood, Carrier Circle |
| 23 James St - East Syracuse | Centro Transit HUB | 23: East Syracuse | James Street, Manlius Street, Fremont Road, Kirkville Road | Bryant & Stratton College, Lincoln Middle School, Eastwood, East Syracuse, Minoa |
| 23 James St - East Syracuse | Centro Transit HUB | 123: East Syracuse Walmart | James Street, Manlius Street, Fremont Road, Kirkville Road | Bryant & Stratton College, Lincoln Middle School, Eastwood, East Syracuse, Minoa |
| 23 James St - East Syracuse | Centro Transit HUB | 323/323X: Minoa | James Street, Manlius Street, Fremont Road, Kirkville Road | Bryant & Stratton College, Lincoln Middle School, Eastwood, East Syracuse, Minoa |
| 26 South Ave | Centro Transit HUB | 26: Corcoran High School | South Avenue, Bellevue Avenue, West Onondaga Avenue & West Onondaga Street, Valley Drive, Onondaga Road, Velasko Road | Corcoran High School, Community General Hospital, Onondaga Community College, Van Duyn Nursing Home, Onondaga Hill 226X, 426, 526 - trips continue on South Avenue and do not serve Bellevue or Onondaga Avenues |
| 26 South Ave | Centro Transit HUB | 126: Upstate Hospital at Community General | South Avenue, Bellevue Avenue, West Onondaga Avenue & West Onondaga Street, Valley Drive, Onondaga Road, Velasko Road | Corcoran High School, Community General Hospital, Onondaga Community College, Van Duyn Nursing Home, Onondaga Hill 226X, 426, 526 - trips continue on South Avenue and do not serve Bellevue or Onondaga Avenues |
| 26 South Ave | Centro Transit HUB | 226/226X: Onondaga Community College | South Avenue, Bellevue Avenue, West Onondaga Avenue & West Onondaga Street, Valley Drive, Onondaga Road, Velasko Road | Corcoran High School, Community General Hospital, Onondaga Community College, Van Duyn Nursing Home, Onondaga Hill 226X, 426, 526 - trips continue on South Avenue and do not serve Bellevue or Onondaga Avenues |
| 26 South Ave | Centro Transit HUB | 326: High Acres via Onondaga Community College | South Avenue, Bellevue Avenue, West Onondaga Avenue & West Onondaga Street, Valley Drive, Onondaga Road, Velasko Road | Corcoran High School, Community General Hospital, Onondaga Community College, Van Duyn Nursing Home, Onondaga Hill 226X, 426, 526 - trips continue on South Avenue and do not serve Bellevue or Onondaga Avenues |
| 26 South Ave | Centro Transit HUB | 426: Upstate Hospital at Community General via Valley Drive | South Avenue, Bellevue Avenue, West Onondaga Avenue & West Onondaga Street, Valley Drive, Onondaga Road, Velasko Road | Corcoran High School, Community General Hospital, Onondaga Community College, Van Duyn Nursing Home, Onondaga Hill 226X, 426, 526 - trips continue on South Avenue and do not serve Bellevue or Onondaga Avenues |
| 26 South Ave | Centro Transit HUB | 526: Onondaga Community College via Valley Drive | South Avenue, Bellevue Avenue, West Onondaga Avenue & West Onondaga Street, Valley Drive, Onondaga Road, Velasko Road | Corcoran High School, Community General Hospital, Onondaga Community College, Van Duyn Nursing Home, Onondaga Hill 226X, 426, 526 - trips continue on South Avenue and do not serve Bellevue or Onondaga Avenues |
| 30 SU - Westcott | Centro Transit HUB | 130: Nottingham High School | Irving Avenue, Waverly Avenue, Euclid Avenue, Westcott Street, East Genesee Street, Erie Boulevard East, Bridge Street | University Hill, Upstate University Hospital, Syracuse University, Nottingham High School, Dewitt, East Syracuse |
| 30 SU - Westcott | Centro Transit HUB | 230: Menorah Park | Irving Avenue, Waverly Avenue, Euclid Avenue, Westcott Street, East Genesee Street, Erie Boulevard East, Bridge Street | University Hill, Upstate University Hospital, Syracuse University, Nottingham High School, Dewitt, East Syracuse |
| 30 SU - Westcott | Centro Transit HUB | 330 Wegman’s Dewitt Park-N-Ride | Irving Avenue, Waverly Avenue, Euclid Avenue, Westcott Street, East Genesee Street, Erie Boulevard East, Bridge Street | University Hill, Upstate University Hospital, Syracuse University, Nottingham High School, Dewitt, East Syracuse |
| 30 SU - Westcott | Centro Transit HUB | 530: East Syracuse Walmart | Irving Avenue, Waverly Avenue, Euclid Avenue, Westcott Street, East Genesee Street, Erie Boulevard East, Bridge Street | University Hill, Upstate University Hospital, Syracuse University, Nottingham High School, Dewitt, East Syracuse |
| 36 Camillus | Centro Transit HUB | 36: Camillus | West Genesee Street, South State Street, Erie Boulevard West | Nation Grid, Westvale, Fairmount, West Genesee High School, Camillus Commons, Camillus |
| 36 Camillus | Centro Transit HUB | 136: Camillus Commons | West Genesee Street, South State Street, Erie Boulevard West | Nation Grid, Westvale, Fairmount, West Genesee High School, Camillus Commons, Camillus |
| 38 Auburn - Syracuse | Centro Transit HUB | 138: Auburn, NY | Grand Ave, Howlett Hill Road, Old Seneca Turnpike, Genesee Street | Western Lights, Township 5, Camillus Commons, Marcellus, Welch Allyn, Auburn |
| 38 Auburn - Syracuse | Auburn | 238: Camillus Commons | Grand Ave, Howlett Hill Road, Old Seneca Turnpike, Genesee Street | Western Lights, Township 5, Camillus Commons, Marcellus, Welch Allyn, Auburn |
| 40 SU - Hospitals | Centro Transit HUB | 40: Syracuse University | Adams Street, Irving Avenue, Waverly Avenue, Comstock Avenue, East Colvin Street, Brighton Avenue | Upstate University Hospital, Syracuse University, Outer Comstock, Meadowbrook, Drumlins Country Club, Nob Hill Apartments, Iroquois Nursing Home |
| 40 SU - Hospitals | Centro Transit HUB | 140: Thurber Street | Adams Street, Irving Avenue, Waverly Avenue, Comstock Avenue, East Colvin Street, Brighton Avenue | Upstate University Hospital, Syracuse University, Outer Comstock, Meadowbrook, Drumlins Country Club, Nob Hill Apartments, Iroquois Nursing Home |
| 40 SU - Hospitals | Centro Transit HUB | 240: Nob Hill | Adams Street, Irving Avenue, Waverly Avenue, Comstock Avenue, East Colvin Street, Brighton Avenue | Upstate University Hospital, Syracuse University, Outer Comstock, Meadowbrook, Drumlins Country Club, Nob Hill Apartments, Iroquois Nursing Home |
| 40 SU - Hospitals | Centro Transit HUB | 340: Drumlins | Adams Street, Irving Avenue, Waverly Avenue, Comstock Avenue, East Colvin Street, Brighton Avenue | Upstate University Hospital, Syracuse University, Outer Comstock, Meadowbrook, Drumlins Country Club, Nob Hill Apartments, Iroquois Nursing Home |
| 40 SU - Hospitals | College Place | 340C: Drumlins | Adams Street, Irving Avenue, Waverly Avenue, Comstock Avenue, East Colvin Street, Brighton Avenue | Upstate University Hospital, Syracuse University, Outer Comstock, Meadowbrook, Drumlins Country Club, Nob Hill Apartments, Iroquois Nursing Home |
| 43 Main Campus | College Place | 43: West Campus | Irving Avenue, Waverly Avenue, East Fayette Street, East Genesee Street, Westcott Street, | Flint Hall, Brewster-Boland Hall, Archbold Gym, Carrier Dome, SUNY ESF, Syracuse Stage, Schine Student Center, Bird Library Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free 243 - Operates in counter-clockwise loop, serving Westcott Street, then East Genesee Street and West Campus 343 - Operates in clock-wise loop, serving East Genesee Street, then Westcott street 443 - After arriving at College Place, trips continue to South Campus |
| 43 Main Campus | College Place | 243: East Genesee & University Ave | Irving Avenue, Waverly Avenue, East Fayette Street, East Genesee Street, Westcott Street, | Flint Hall, Brewster-Boland Hall, Archbold Gym, Carrier Dome, SUNY ESF, Syracuse Stage, Schine Student Center, Bird Library Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free 243 - Operates in counter-clockwise loop, serving Westcott Street, then East Genesee Street and West Campus 343 - Operates in clock-wise loop, serving East Genesee Street, then Westcott street 443 - After arriving at College Place, trips continue to South Campus |
| 43 Main Campus | College Place | 343: Westcott Street & Euclid Avenue | Irving Avenue, Waverly Avenue, East Fayette Street, East Genesee Street, Westcott Street, | Flint Hall, Brewster-Boland Hall, Archbold Gym, Carrier Dome, SUNY ESF, Syracuse Stage, Schine Student Center, Bird Library Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free 243 - Operates in counter-clockwise loop, serving Westcott Street, then East Genesee Street and West Campus 343 - Operates in clock-wise loop, serving East Genesee Street, then Westcott street 443 - After arriving at College Place, trips continue to South Campus |
| 43 Main Campus | College Place | 443: The Warehouse | Irving Avenue, Waverly Avenue, East Fayette Street, East Genesee Street, Westcott Street, | Flint Hall, Brewster-Boland Hall, Archbold Gym, Carrier Dome, SUNY ESF, Syracuse Stage, Schine Student Center, Bird Library Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free 243 - Operates in counter-clockwise loop, serving Westcott Street, then East Genesee Street and West Campus 343 - Operates in clock-wise loop, serving East Genesee Street, then Westcott street 443 - After arriving at College Place, trips continue to South Campus |
| 44 Manley Field House | College Place | 44: Manley South Parking Lot | Comstock Avenue, Small Road, Skytop Road, Slocum Drive, Lambreth Lane, Winding Ridge Road | College Place, Manley Field House, Goldstein Student Center, Skyhall, Skytop Office Building Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free. 344 - Select trips serve Skyhall both before and after serving the Skytop Office Building |
| 44 Manley Field House | College Place | 244: Goldstein Student Center | Comstock Avenue, Small Road, Skytop Road, Slocum Drive, Lambreth Lane, Winding Ridge Road | College Place, Manley Field House, Goldstein Student Center, Skyhall, Skytop Office Building Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free. 344 - Select trips serve Skyhall both before and after serving the Skytop Office Building |
| 44 Manley Field House | College Place | 344: Skytop | Comstock Avenue, Small Road, Skytop Road, Slocum Drive, Lambreth Lane, Winding Ridge Road | College Place, Manley Field House, Goldstein Student Center, Skyhall, Skytop Office Building Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free. 344 - Select trips serve Skyhall both before and after serving the Skytop Office Building |
| 44 Manley Field House | College Place | 444: Small Road & Lambreth Lane | Comstock Avenue, Small Road, Skytop Road, Slocum Drive, Lambreth Lane, Winding Ridge Road | College Place, Manley Field House, Goldstein Student Center, Skyhall, Skytop Office Building Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free. 344 - Select trips serve Skyhall both before and after serving the Skytop Office Building |
| 45 SU - Destiny USA | College Place | 45: Destiny USA | Irving Avenue, Comstock Avenue, East Colvin Avenue, Jamesville Avenue, Brighton Avenue, Thurber Street | College Place, Destiny USA, Manley Field House, SU Physical Plant, Clarendon Heights, Hidden Valley, Remington Gardens Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free. 45 - Operates Saturdays, late afternoon & early evenings only 345 - Operates Weekdays, early & late mornings only |
| 45 SU - Destiny USA | College Place | 345: Thurber Street | Irving Avenue, Comstock Avenue, East Colvin Avenue, Jamesville Avenue, Brighton Avenue, Thurber Street | College Place, Destiny USA, Manley Field House, SU Physical Plant, Clarendon Heights, Hidden Valley, Remington Gardens Syracuse University campus shuttle route. Operates only when classes are in session August - May. Students and staff ride free. 45 - Operates Saturdays, late afternoon & early evenings only 345 - Operates Weekdays, early & late mornings only |
| 46 Liverpool - Rt. 57 | Centro Transit HUB | 46: Wegmans – Route 31 | South State Street, Old Liverpool Road, Route 57, Soule Road, Route 31, Route 481 | Upstate University Hospital, Syracuse University, Destiny USA, Liverpool, Great Northern Mall, Oswego, Fulton |
| 46 Liverpool - Rt. 57 | Centro Transit HUB | 246/246X: Oswego | South State Street, Old Liverpool Road, Route 57, Soule Road, Route 31, Route 481 | Upstate University Hospital, Syracuse University, Destiny USA, Liverpool, Great Northern Mall, Oswego, Fulton |
| 46 Liverpool - Rt. 57 | Fulton | 346: Oswego | South State Street, Old Liverpool Road, Route 57, Soule Road, Route 31, Route 481 | Upstate University Hospital, Syracuse University, Destiny USA, Liverpool, Great Northern Mall, Oswego, Fulton |
| 48 Liverpool - Morgan Rd | Centro Transit HUB | 48: Grampian Road | South State Street, Old Liverpool Road, John Glenn Boulevard, Route 57 | Destiny USA, Liverpool, Bayberry, Wegmans Liverpool |
| 48 Liverpool - Morgan Rd | Centro Transit HUB | 148: Wegmans via Bayberry | South State Street, Old Liverpool Road, John Glenn Boulevard, Route 57 | Destiny USA, Liverpool, Bayberry, Wegmans Liverpool |
| 48 Liverpool - Morgan Rd | Centro Transit HUB | 248: Wegmans via John Glenn Boulevard | South State Street, Old Liverpool Road, John Glenn Boulevard, Route 57 | Destiny USA, Liverpool, Bayberry, Wegmans Liverpool |
| 50 Destiny USA | Centro Transit HUB | 50: Destiny USA via I-81 | South State Street, I-81, Solar Street, Park Street | Franklin Square, Inner Harbor, Regional Transportation Center, Destiny USA |
| 50 Destiny USA | Centro Transit HUB | 550: Destiny USA via Solar Street | South State Street, I-81, Solar Street, Park Street | Franklin Square, Inner Harbor, Regional Transportation Center, Destiny USA |
| 510 Tully - LaFayette | Centro Transit HUB | 510: Tully Community Church Park-N-Ride | Adams Street, Harrison Street, I-81, Route 11 | SUNY Upstate Hospital, Tully, LaFayette |
| 52 Court St | Centro Transit HUB | 52: Shop City | North Salina Street, Townsend Street, Butternut Street, Park Street, Grant Boulevard, Court Street, Molloy Road | Northside, Grant Middle School, Shop City, Henninger High School |
| 52 Court St | Centro Transit HUB | 152: Industrial Park | North Salina Street, Townsend Street, Butternut Street, Park Street, Grant Boulevard, Court Street, Molloy Road | Northside, Grant Middle School, Shop City, Henninger High School |
| 54 Midland | Centro Transit HUB | 54: Matson | South Salina Street, South Avenue, Midland Avenue, Ballantyne Road, Valley Drive, Seneca Turnpike | One Centro Center, Shop Rite, Meachem Field, Valley Vista Apartments, Bernadine Apartments, Valley Plaza |
| 54 Midland | Centro Transit HUB | 254: Valley Plaza | South Salina Street, South Avenue, Midland Avenue, Ballantyne Road, Valley Drive, Seneca Turnpike | One Centro Center, Shop Rite, Meachem Field, Valley Vista Apartments, Bernadine Apartments, Valley Plaza |
| 58 Parkhill | Centro Transit HUB | 58: Bishop Grimes High School | Washington Street, Burnet Avenue, Thompson Road | Midtown, Eastwood, Carrier Circle, East Syracuse |
| 62 Fayetteville | Centro Transit HUB | 62: Towne Center at Fayetteville | East Genesee Street, I-690, I-481, Widewaters Parkway, Route 92, Route 257 | Widewaters Parkway, Dewitt Wegmans Park-N-Ride, SUNY Upstate Hospital, Towne Center at Fayetteville, Northeast Medical Center, Fayetteville, Manlius |
| 62 Fayetteville | Centro Transit HUB | 162: Manlius via I-690 & Widewaters Parkway | East Genesee Street, I-690, I-481, Widewaters Parkway, Route 92, Route 257 | Widewaters Parkway, Dewitt Wegmans Park-N-Ride, SUNY Upstate Hospital, Towne Center at Fayetteville, Northeast Medical Center, Fayetteville, Manlius |
| 62 Fayetteville | Centro Transit HUB | 262: Manlius via East Genesee Street | East Genesee Street, I-690, I-481, Widewaters Parkway, Route 92, Route 257 | Widewaters Parkway, Dewitt Wegmans Park-N-Ride, SUNY Upstate Hospital, Towne Center at Fayetteville, Northeast Medical Center, Fayetteville, Manlius |
| 62 Fayetteville | Centro Transit HUB | 262X: Manlius via I-481 & SUNY Upstate Hospital | East Genesee Street, I-690, I-481, Widewaters Parkway, Route 92, Route 257 | Widewaters Parkway, Dewitt Wegmans Park-N-Ride, SUNY Upstate Hospital, Towne Center at Fayetteville, Northeast Medical Center, Fayetteville, Manlius |
| 62 Fayetteville | Centro Transit HUB | 362: Wegmans Dewitt Park-N-Ride via I-690 & Widewaters Parkway | East Genesee Street, I-690, I-481, Widewaters Parkway, Route 92, Route 257 | Widewaters Parkway, Dewitt Wegmans Park-N-Ride, SUNY Upstate Hospital, Towne Center at Fayetteville, Northeast Medical Center, Fayetteville, Manlius |
| 62 Fayetteville | Centro Transit HUB | 462: Manlius via I-690 & I-481 | East Genesee Street, I-690, I-481, Widewaters Parkway, Route 92, Route 257 | Widewaters Parkway, Dewitt Wegmans Park-N-Ride, SUNY Upstate Hospital, Towne Center at Fayetteville, Northeast Medical Center, Fayetteville, Manlius |
| 64 Western Lights | Centro Transit HUB | 64: Western Lights via West Onondaga Street | Gifford Street, West Onondaga Street, Bellevue Avenue, Grand Avenue, Fay Road | Near Westside, Western Lights Plaza, Taunton, Bishop Ludden High School |
| 64 Western Lights | Centro Transit HUB | 164: Bellevue Avenue via Western Lights | Gifford Street, West Onondaga Street, Bellevue Avenue, Grand Avenue, Fay Road | Near Westside, Western Lights Plaza, Taunton, Bishop Ludden High School |
| 64 Western Lights | Centro Transit HUB | 264: St. Camillus via West Onondaga Street | Gifford Street, West Onondaga Street, Bellevue Avenue, Grand Avenue, Fay Road | Near Westside, Western Lights Plaza, Taunton, Bishop Ludden High School |
| 64 Western Lights | Centro Transit HUB | 364: Western Lights via Grand Avenue | Gifford Street, West Onondaga Street, Bellevue Avenue, Grand Avenue, Fay Road | Near Westside, Western Lights Plaza, Taunton, Bishop Ludden High School |
| 64 Western Lights | Centro Transit HUB | 464: St. Camillus via Grand Avenue | Gifford Street, West Onondaga Street, Bellevue Avenue, Grand Avenue, Fay Road | Near Westside, Western Lights Plaza, Taunton, Bishop Ludden High School |
| 68 E. Fayette - Erie Blvd | Centro Transit HUB | 68: Westmoreland Avenue | East Fayette Street, Erie Boulevard East, Bridge Street | Midtown, Rolling Green Estates, Erie Boulevard retail corridor, DeWitt, East Syracuse Walmart |
| 68 E. Fayette - Erie Blvd | Centro Transit HUB | 168: Widewaters Parkway | East Fayette Street, Erie Boulevard East, Bridge Street | Midtown, Rolling Green Estates, Erie Boulevard retail corridor, DeWitt, East Syracuse Walmart |
| 72 Townsend - E. Colvin | Centro Transit HUB | 72: Toomey Abbott Apartments | Oakwood Avenue, Garfield Avenue, East Colvin Street, Comstock Avenue | Pioneer Homes, Central Village, Almus Oliver Apartments, Manley Field House, Loretto & Iroquois Nursing Homes |
| 72 Townsend - E. Colvin | Centro Transit HUB | 172: Loretto Health & Rehab | Oakwood Avenue, Garfield Avenue, East Colvin Street, Comstock Avenue | Pioneer Homes, Central Village, Almus Oliver Apartments, Manley Field House, Loretto & Iroquois Nursing Homes |
| 74 Solvay | Centro Transit HUB | 74: Solvay via Milton Avenue | Gifford Street, Avery Avenue, Milton Avenue | Near Westside, PSLA @ Fowler High School, Solvay |
| 74 Solvay | Centro Transit HUB | 274: Solvay via Avery Avenue | Gifford Street, Avery Avenue, Milton Avenue | Near Westside, PSLA @ Fowler High School, Solvay |
| 74 Solvay | Centro Transit HUB | 374: Township 5 | Gifford Street, Avery Avenue, Milton Avenue | Near Westside, PSLA @ Fowler High School, Solvay |
| 76 Salt Springs | Centro Transit HUB | 76: Le Moyne College | East Genesee Street, Salt Springs Road, Bridge Street | Midtown, Eastside, Le Moyne College, DeWitt |
| 76 Salt Springs | Centro Transit HUB | 176: Widewaters Parkway | East Genesee Street, Salt Springs Road, Bridge Street | Midtown, Eastside, Le Moyne College, DeWitt |
| 80 Grant Blvd | Centro Transit HUB | 80: Shop City | James Street, Butternut Street, Grant Boulevard | Northside, Eastwood, Shop City, Grant Village Apartments, Eastwood Homes |
| 80 Grant Blvd | Centro Transit HUB | 180: Taft & Dunlap Avenues | James Street, Butternut Street, Grant Boulevard | Northside, Eastwood, Shop City, Grant Village Apartments, Eastwood Homes |
| 82 Baldwinsville | Centro Transit HUB | 82: Baldwinsville – Spruce Street | State Fair Boulevard, I-690, Downer Street | Baldwinsville, Fairgrounds, Destiny USA. 682 - Regular service operates Saturday & Sunday only, Memorial Day – Labor Day. Special event service operates for events at the Lakeview Amphitheater. During the New York State Fair, service is replaced by various Park-N-Ride shuttles. |
| 82 Baldwinsville | Centro Transit HUB | 182: Baldwinsville – Mott Road via Indian Springs | State Fair Boulevard, I-690, Downer Street | Baldwinsville, Fairgrounds, Destiny USA. 682 - Regular service operates Saturday & Sunday only, Memorial Day – Labor Day. Special event service operates for events at the Lakeview Amphitheater. During the New York State Fair, service is replaced by various Park-N-Ride shuttles. |
| 82 Baldwinsville | Centro Transit HUB | 682: Lakeview Park/Fairgrounds | State Fair Boulevard, I-690, Downer Street | Baldwinsville, Fairgrounds, Destiny USA. 682 - Regular service operates Saturday & Sunday only, Memorial Day – Labor Day. Special event service operates for events at the Lakeview Amphitheater. During the New York State Fair, service is replaced by various Park-N-Ride shuttles. |
| 84 Mattydale | Centro Transit HUB | 84: Brewerton Road | Brewerton Road, Molloy Road, Allen Road, Chestnut Street | Northside, Mattydale, Northern Lights Plaza, North Syracuse |
| 84 Mattydale | Centro Transit HUB | 184 Allen Road | Brewerton Road, Molloy Road, Allen Road, Chestnut Street | Northside, Mattydale, Northern Lights Plaza, North Syracuse |
| 86 Henry Clay Blvd | Centro Transit HUB | 186: Wetzel Road via YMCA | South State Street, I-81, Buckley Road, Taft Road, Henry Clay Boulevard, Wetzel Road | Salina, North Medical Center, Liverpool |
| 86 Henry Clay Blvd | Centro Transit HUB | 286 Wetzel Road | South State Street, I-81, Buckley Road, Taft Road, Henry Clay Boulevard, Wetzel Road | Salina, North Medical Center, Liverpool |
| 88 North Syracuse | Centro Transit HUB | 88: Cicero Wegmans Park-N-Ride | South State Street, I-81, Brewerton Road | Syracuse University, SUNY Upstate, Destiny USA, Airport Plaza Park-N-Ride, Cicero Wegmans Park-N-Ride, North Syracuse, Cicero, Central Square All 88, 188, 288, and 388 trips operate express between Downtown Syracuse and Northern Lights Plaza Select trips operate to Destiny USA 288 – Operates express between North Syracuse and Central Square 388X – Operates express between Downtown Syracuse and Central Square |
| 88 North Syracuse | Centro Transit HUB | 188: Cicero Commons | South State Street, I-81, Brewerton Road | Syracuse University, SUNY Upstate, Destiny USA, Airport Plaza Park-N-Ride, Cicero Wegmans Park-N-Ride, North Syracuse, Cicero, Central Square All 88, 188, 288, and 388 trips operate express between Downtown Syracuse and Northern Lights Plaza Select trips operate to Destiny USA 288 – Operates express between North Syracuse and Central Square 388X – Operates express between Downtown Syracuse and Central Square |
| 88 North Syracuse | Centro Transit HUB | 288: Central Square via North Syracuse | South State Street, I-81, Brewerton Road | Syracuse University, SUNY Upstate, Destiny USA, Airport Plaza Park-N-Ride, Cicero Wegmans Park-N-Ride, North Syracuse, Cicero, Central Square All 88, 188, 288, and 388 trips operate express between Downtown Syracuse and Northern Lights Plaza Select trips operate to Destiny USA 288 – Operates express between North Syracuse and Central Square 388X – Operates express between Downtown Syracuse and Central Square |
| 88 North Syracuse | Centro Transit HUB | 388: Central Square via Cicero & North Syracuse | South State Street, I-81, Brewerton Road | Syracuse University, SUNY Upstate, Destiny USA, Airport Plaza Park-N-Ride, Cicero Wegmans Park-N-Ride, North Syracuse, Cicero, Central Square All 88, 188, 288, and 388 trips operate express between Downtown Syracuse and Northern Lights Plaza Select trips operate to Destiny USA 288 – Operates express between North Syracuse and Central Square 388X – Operates express between Downtown Syracuse and Central Square |
| 88 North Syracuse | Centro Transit HUB | 388X: Central Square Express | South State Street, I-81, Brewerton Road | Syracuse University, SUNY Upstate, Destiny USA, Airport Plaza Park-N-Ride, Cicero Wegmans Park-N-Ride, North Syracuse, Cicero, Central Square All 88, 188, 288, and 388 trips operate express between Downtown Syracuse and Northern Lights Plaza Select trips operate to Destiny USA 288 – Operates express between North Syracuse and Central Square 388X – Operates express between Downtown Syracuse and Central Square |
| 90 Wegmans Shopper | Wegmans | Various | James Street, West Onondaga Street, Brewerton Road, East Genesee Street | Direct service from various Nursing & Senior Living Facilities to Wegmans store locations in Eastwood, Cicero, Western Lights, and DeWitt |
| 92 TOPS Shopper | TOPS | Various | Grant Boulevard, Brewerton Road, East Genesee Street, Nottingham Road | Direct service from various Nursing & Senior Living Facilities to TOPS store locations in North Syracuse, Shop City, Fayetteville, Meadowbrook |
| 94 J Lot Shuttle | J Lot | 94: VA Medical Center | Cortland Avenue, Adams Street, Irving Ave | Parking lot shuttle for Syracuse VA Medical Center employees |
| Community Extra | CBA, Bishop Grimes, Bishop Ludden, Corcoran HS, PSLA @ Fowler HS, Henninger HS, ITC HS, Nottingham HS, OnTECH Charter HS, Syracuse Academy of Science Charter HS | Various | North Salina Street, Court Street, Park Street, Butternut Street, Grant Boulevard, Lodi Street, James Street, Burnet Avenue, Teall Avenue, Midler Avenue, East Genesee Street, Salt Springs Road, Euclid Avenue, Meadowbrook Drive, East Colvin Street, Jamesville Avenue, Townsend Avenue, South Salina Street, Brighton Avenue, Midland Avenue, Ballantyne Road, Valley Drive, South Avenue, Bellevue Avenue, West Onondaga Street, Grace Street, Gifford Street, Grand Avenue, Winkworth Parkway, Avery Avenue, Milton Avenue, West Genesee Street | Direct service provided to all public, charter, and parochial high schools attended by students who reside within the Syracuse City School District. Routes deviate greatly from regular bus routes to better serve neighborhoods and schools. Routes have a four digit number - the first two digits identify the school served; by using the number of the regular route that serves the school, and the last two digits identify the general area served; by using the number of the regular route for that area. For example, route "2610 Glenwood - S. Salina St" serves Corcoran High School (route #26) and provides extra service to the S. Salina St. area (route #10). |