OpenLLM-France/wikimedia huggingface dataset:
# SMC6

Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene.

## Structure

The SMC6 was discovered first in fission yeast as RAD18 (SMC6). It forms a heterodimeric complex with Spr18 (SMC5) protein. In yeast, SMC5/6 complex has sub-units which consists of SMC5, SMC6 and six nonstructural maintenance of chromosomes (NSE) proteins. Nse1-Nse3-Nse4 subunits bridge the Smc5 head Smc6 and allow the binding of DNA.
It is potentially involved in the Alternative lengthening of telomeres cancer mechanism.

## Nse subunits

Nse1-Nse3-Nse4 subunits bridge the heads of the Smc5 and Smc6 proteins and allow the complex to bind DNA. Nse5 and Nse6 form a sub-complex which localizes to the head of the SMC5/6 complex in the budding yeast Saccharomyces cerevisiae, and to the hinges of the SMC5/6 complex in the fission yeast Schizosaccharomyces pombe. The Nse5/6 sub-complex is required for the replication of S. cerevisiae, but has not been characterized as essential in S. pombe. Orthologous proteins to Nse5-Nse6 exist in other eukaryotes, namely ASAP1-SNI1 in Arabidopsis thaliana and SLF1-SLF2 in humans, which are believed have similar function to their Nse counterparts. The localization of SLF1 and SLF2 on the human SMC5/6 complex is unknown.

## Localization

The Smc5/6 complex has localization methods which are not heavily conserved. In humans the complex is localized to viral DNA sequences using SMC5/6 localization factors 1 and 2 (SLF1 and SLF2) which contributes to viral resistance. In the plant A. thaliana, this heterodimer can be localized to double stranded breaks for homologous recombination using the SWI3B complex of the SWI/SNF pathway. Once localized to the DNA, the SCM5/6 complex non-specifically binds to ~20 DNA base pairs.

## Role in recombination and meiosis

Smc6 and Smc5 proteins form a heterodimeric ring-like structure and together with other non-SMC elements form the SMC-5/6 complex. In the worm Caenorhabditis elegans this complex interacts with the HIM-6(BLM) helicase to promote meiotic recombination intermediate processing and chromosome maturation. The SMC-5/6 complex in mouse oocytes is essential for the formation of segregation competent bivalents during meiosis. In the yeast Saccharomyces cerevisiae, SMC6 is necessary for resistance to DNA damage as well as for damage-induced interchromosomal and sister chromatid recombination. In humans, a chromosome breakage syndrome characterized by severe lung disease in early childhood is associated with a mutation in a component of the SMC-5/6 complex. Patient’s cells display chromosome rearrangements, micronuclei, sensitivity to DNA damage and defective homologous recombination.
# Bethany Baptist Church (Newark, New Jersey)

Bethany Baptist Church is a historic church at 117 W. Market Street in Newark, Essex County, New Jersey, United States.
The church traces its origins to 1870, when a group of African Americans established the church on Broad Street in Newark in the building of the Peddie Memorial Baptist Church. Under the leadership of the Reverend Ebenezer Bird, who had come from Virginia to lead the congregation of about 26 members, the group was officially sanctioned as a church by the Council of Baptist Churches in June 1871. Thus, the church prides itself on being the "first Baptist congregation founded by people of African descent."
The Romanesque style church building was constructed in 1866. It was added to the National Register of Historic Places in 1989.
The church was under the stewardship of M. William Howard, Jr., from 2000 to 2015.
The old building appears to have been replaced by a housing complex, which has been replaced by a new building at 275 W. Market Street. The new building was dedicated on May 2, 1976.
# Yodi Karone

Yodi Karone (born Alan Dye, 15 March 1954) is a writer of Cameroonian origin. He is the author (in French) of four novels and a play; his novel Nègre de Paille won the Grand prix littéraire d'Afrique noire in 1982. In the 1980s he was one of the "leading young novelists" of a group of writers of African descent who lived in Paris.

## Career

Karone started as a playwright; his first play was Palabres de nuit ("Discussions of Night") in 1978. A second play was published in 1980, Sacré dernier. After that he wrote novels. Karone was a musician and a sculptor also, and this influenced his writing; he drew on "rhythm and visual images to enhance his narrative".
Le bal des caïmans, his first novel, is political, describing injustices suffered when an entire population is oppressed and repressed; a man is chased and captured, and put on trial. The testimony of the witnesses at this parody of a trial make up the novel. According to Ange-Séverin Malanda and Thomas Mpoyi-Buatu, who interviewed Karone in 1980, the limited perspective offered by these characters enhances the force of their experience even while it expressed errors and contradictions. Malanda and Mpoyi-Buatu said this stylistic feature was new in the African novel, and contributed to the idea of a search for subjectivity. Karone said he chose to have the caiman, an animal that does not actually live in Africa, in the title to express a distance from any particular country and achieve a kind of universality.
His 1988 novel A la Recherche du cannibale amour opens in the metro station Châtelet, in Paris, where the protagonist, a novelist from Africa, listens to a saxophone player, and promptly loses the manuscript for his novel. This starts a search that takes him to Cameroon and then to Harlem, and then back.

## Works
### Drama

* Palabres de nuit (1978)
* Sacré dernier (1980)

### Fiction

* Le bal des Caïmans (1980)
* Nègre de Paille (1982)
* A la Recherche du cannibale amour (1988)
* Les beaux gosses (1988)
# Broomhead

Broomhead is a surname of English origin and was a surname based on the location of the person it was given to. This surname is most commonly found in North Central England.

## History

The surname first appears on record in Yorkshire, England in 1290 with the name Henry de Bromeheuede. Surnames were created in England at that time due to the introduction of personal taxes known at that time as Poll Tax. Throughout the centuries, surnames varied in spelling. The surname Broomhead was variously spelt Bromehe(a)d, Bromhead, Bromet, Brumhead, Brummitt and more.

## Present day

The surname today is still most prevalent in the UK. Despite that, it is a rare surname and it is estimated that for every million people in the UK, only 27 have the surname Broomhead.
The surname is also found in the following countries,
* USA
* Canada
* France
* Germany
* South Africa
* Australia (see "Notable people" section below).
* New Zealand

## Notable people

* David Broomhead (1950-2014), British mathematician
* Malcolm Broomhead (born 1952), Australian businessman
* Tim Broomhead (born 1994), Australian rules footballer
* Mark Broomhead, bassist of Christian metal band Seventh Angel and vocalist/bassist of thrash metal band Detritus.

## Places

* Broomhead Hall, South Yorkshire
* Broomhead Reservoir, South Yorkshire
# Red turtle

Red turtle may refer to:
* Red side-necked turtle, a species of turtle found in Colombia and possibly Peru and Brazil.
* Red-eared slider, the most popular pet turtle species in the United States and a popular pet turtle around the world.
* Red-faced turtle, a turtle found across much of northern Australia.
* Painted turtle, the most widespread native turtle of North America. Can have a red line on the top shell or a red pattern on the bottom shell.
* Red-crowned roofed turtle
* Red-necked pond turtle
* Red-bellied short-necked turtle
* Red-headed Amazon River turtle
* Pseudemys, a turtle genus, known as cooters with several red-bellied turtle species.
** Alabama red-bellied cooter
** Florida red-bellied cooter
** Northern red-bellied cooter
* The Red Turtle, 2016 animated film
# Jodis inumbrata

Jodis inumbrata is a species of moth of the family Geometridae. It is found in Bhutan and Taiwan.
# Webb Island

Webb Island (67°27′S 67°56′W﻿ / ﻿67.450°S 67.933°W﻿ / -67.450; -67.933) is a rocky island in Antarctica, 1.5 nautical miles (2.8 km) long, lying in Laubeuf Fjord about 3 nautical miles (6 km) south of the entrance to Stonehouse Bay, close to Adelaide Island. It was discovered by the French Antarctic Expedition under Jean Baptiste Charcot, 1908–10, and named by him for Captain (later Admiral Sir) Richard C. Webb of the Royal Navy, commanding officer of an English cruiser in Argentine waters at that time.
# Pitthea famula

Pitthea famula is a species of moth in the family Geometridae. It was first described by Dru Drury in 1773 from Calabar, in what is now Nigeria. It is found in Angola, Benin, Cameroon, the Republic of the Congo, the Democratic Republic of the Congo, Equatorial Guinea (Bioko), Nigeria, Sierra Leone and Zambia.

## Description

Upperside: antennae long and pectinated (comb like). Thorax spiral. Neck orange. Thorax and abdomen dusky grey. Anterior wings about halfway from the tips black, but at the base are of a pellucid (transparent) white; being surrounded along the anterior edge and part of the posterior with black; an oblong white spot is placed near the tips on the black part. Posterior wings black and white; the white entirely surrounded by the black, which on the anterior and abdominal edges is very narrow.
Underside: palpi orange, black at the tips. Neck, breast, and sides orange. Feet black. Thighs white. Abdomen white, annulated with dusky grey. Anterior wings as on the upperside, the black parts being of a russet hue. Posterior wings differ a little, the white part running down to the middle of the external edges, with a white spot at the upper corners. Margins of the wings entire.
Wingspan 2 inches (50 mm).
# Shigeru Sugishita

Shigeru Sugishita (杉下 茂, Sugishita Shigeru, September 17, 1925 – June 12, 2023) was a Japanese professional baseball pitcher and coach. Renowned for his forkball, Sugishita dominated the Central League from 1950–1955, winning more than 30 games twice (winning at least 23 games each season), and garnering three Eiji Sawamura Awards. Sugishita usually split his time between starting games and pitching in relief. He played 11 seasons, ten of them for the Chunichi/Nagoya Dragons.

## Biography

Born in Tokyo Prefecture, Sugishita attended Teikyo Shogyo High School and Meiji University.
In 1950, Sugishita led the Central League in strikeouts and innings pitched. In 1951, he went 28-13 with a 2.36 ERA, leading the Central League in victories and winning his first Eiji Sawamura Award. 1952 was another stellar campaign for Sugishita, as he went 32-14 with a 2.33 ERA, pitching in 61 games and throwing 355+2⁄3 innings. That year he again won the Sawamura Award.
In 1954, Sugishita won his third Sawamura Award, going 32-12 with a 1.39 ERA. He pitched 395+1⁄3 innings, had 27 complete games, 7 shutouts, and 273 strikeouts, and was named Most Valuable Player of the Central League. Capping off the season, he was the MVP of 1954 Japan Series, pitching in four of the seven games and winning three of them, including the game-seven clincher. He is one of only three players in NPB history to win the Sawamura Award, the MVP award, and the Japan Series MVP in the same season.
Despite only being 32 years old, Sugishita retired from playing after the 1958 season and became the Dragons' manager. After guiding the team for two seasons, Sugishita was let go after the 1960 season, when the Dragons finished in fifth place.
In 1961, Sugishita returned to playing, pitching mostly in relief for the Daimai Orions. He went 4-6 with a respectable 2.44 ERA.
Sugishita went back to managing, leading the Hanshin Tigers in 1966, and returning to Chunichi in 1968. His teams did not perform well, and Sugishita moved on to announcing baseball on television.
Shigeru Sugishita was elected to the Japanese Baseball Hall of Fame in 1985.
Sugishita died of pneumonia at a Tokyo hospital on June 12, 2023, at the age of 97.
# Paul Ururuka

Paul Omerenyia Ururuka (1910-1970) was a former Minister of Works in the Old Eastern Region of Nigeria and a former Minister of Commerce, and of Transport in the Administration of Dr. Michael Okpara, the Premier of Eastern Nigeria. In 1965, he was conferred with the National Honour of the Commander of the Federal Republic (CFR) by the President, Rt. Hon. Dr. Nnamdi Azikiwe, in recognition of his services to Nigeria.

## Early life and education

Ururuka was born in 1910 in Umunkpeyi, Nvosi, Isiala Ngwa South of Abia State, Nigeria to Mr. Ururuka Ajereh and Orianu Ururuka Ajereh. He obtained his Standard Six Certificate with distinction from Christ the King School, Aba. He later enrolled at the St. Charles Teachers' Training College, Onitsha, obtaining a Teacher Grade II and later Grade I Certificates and subsequently enrolled for the General Certificate of Education, London as a private student. For further education, Ururuka proceeded to the Trinity College, Dublin, where he obtained a Bachelor of Arts in Geography and an MSc in Geography.

## Career

Ururuka was elected in 1954 to represent Ngwaland in the Eastern Region House of Assembly, and was later appointed Minister in the Cabinet of Dr. Nnamdi Azikiwe and Dr. Michael Okpara. He held several cabinet positions in the Eastern Region.

## Statue and immortalization

A statue of Ururuka was erected at the Obikabia Junction in Aba by Dr. Okezie Ikpeazu, the then Governor of Abia State to immortalise him. Ururuka is fondly remembered for bringing infrastructural development to Ngwa land, and for building strong and durable road networks which have stood the test of time, facilitating commerce, logistics and road travel.
# S78

S78 may refer to:
* S78 (New York City bus) serving Staten Island
* County Route S78 (California)
* Greek submarine Poseidon (S-78)
# Bethany Baptist Church (New York City)

Bethany Baptist Church is a Baptist church located at 303 West 153rd Street in Manhattan, New York City. The church building was originally built for as the Washington Heights Evangelical Lutheran Church, built 1921 to designs by architect Francik Averkamp of 600 West 181st Street. A minor brick and stone fence was built in 1911 to designs by Upjohn & Conable, indicating an earlier building.
Bethany Baptist was founded by the Rev. John Joseph on February 12, 1932 at 327 West 126th Street, New York City. There is no current pastor at this time.
# Broomhead Reservoir

Broomhead Reservoir is a reservoir located in the Ewden Valley, near Sheffield in South Yorkshire, England. The reservoir is located to the south of Bolsterstone and is linked to the More Hall Reservoir to the east. It covers 50 hectares (120 acres) of land and can hold more than 1,000 million gallons of water.

## History

The reservoir, like the neighbouring More Hall Reservoir, was first planned by the Corporation of Sheffield in the late 19th century after a chronic shortage of clean water around the city had led to outbreaks of cholera. Broomhead was planned to be the main "supply" reservoir. Following a dispute over who owned the rights to the land, construction of the reservoirs started in 1913, but was interrupted because of the outbreak of the First World War, and did not restart until 1920. Four years later, workers noticed a land slip north of the reservoir site while digging a channel, which required a 50-foot drain and removing 400,000 cubic yards of soil to fix.
Work was completed in 1934. Ground movement continued to be problematic after the reservoir began to be used, and required further remodelling the landscape and removing another 160,000 cubic yards of soil. In all, remedial work on the reservoirs is believed to have cost as much as the original construction.
The reservoir was originally maintained by the Sheffield Corporation Waterworks Department. It is now operated by Yorkshire Water.

## Tourism

The reservoir and surrounding land are open for ramblers. In 2014, the weir leading the reservoir was unblocked to allow wild brown trout to reach it for the first time. Fishing is allowed in the reservoir, as is sailing and water sports.
Broomhead, like several other reservoirs, has people swimming in hot weather. In 2012, a group set up a camp by the reservoir and built a rope swing for people to dive into the water. Yorkshire Water condemned the action, highlighting the reservoir has a strong current that could prove fatal even for experienced swimmers. Despite signs reading "Cold water kills – bathing prohibited" around the reservoir, it has continued to attract open water swimmers.
# Red urine

Red urine may refer to:
* Beeturia, betacyanin-colored urine
* Blood-colored urine, including:
** Hematuria, the presence of red blood cells (erythrocytes) in the urine
** Hemoglobinuria, excess hemoglobin filtered by the kidneys into the urine
# Webb Lake

Webb Lake may refer to:
* Webb Lake (Antarctica), a lake in Victoria Land, Antarctica
* Webb Lake (Maine), a lake
* Webb Lake, Wisconsin, a town
** Webb Lake (community), Wisconsin, an unincorporated community within the town
# Pioneer Trail (film)

Pioneer Trail is a 1938 American Western film directed by Joseph Levering and starring Jack Luden, Joan Barclay and Slim Whitaker.

## Cast

* Jack Luden as Breezy
* Joan Barclay as Alice Waite
* Slim Whitaker as Curley
* Leon Beaumon as Henchman Joe
* Hal Taliaferro as Henchman Smokey
* Marin Sais as Belle
* Eva McKenzie as Ma Allen
* Hal Price as Baron Waite
* Dick Botiller as Pedro
* Tom London as Sam Harden
# Kane County

Kane County is the name of two counties in the United States:
* Kane County, Illinois
** Kane County Cougars, a minor league baseball team based in Kane County, Illinois
* Kane County, Utah
# Paulo Adriano

Paulo Adriano Almeida Simões (born 3 March 1977 in Anadia, Aveiro District), known as Adriano, is a Portuguese former footballer who played as a midfielder.

## Honours

Brașov
* Liga II: 2007–08
Anadia
* Terceira Divisão: 2009–10
# S79

S79 may refer to:
* County Route S79 (Bergen County, New Jersey)
* Expressway S79 (Poland)
* Green Sea Airport in Horry County, South Carolina, United States
* INS Dolphin (S79), a submarine of the Israeli Navy
* S79 Select Bus Service (New York City bus) serving Staten Island
* Savoia-Marchetti S.79, an Italian bomber
# San Josécito

San Josecito is a district of the Alajuelita canton, in the San José province of Costa Rica.

## Geography

San Josecito has an area of 2.42 km$^2$ and an elevation of 1,200 metres.

## Demographics

For the 2011 census, San Josecito had a population of 10,506 inhabitants.

## Transportation
### Road transportation

The district is covered by the following road routes:
* National Route 105
* National Route 217
# Yellow-throated squirrel

The yellow-throated squirrel (Sciurus gilvigularis) is a tree squirrel in the genus Sciurus endemic to South America. It is found in Brazil, Guyana and Venezuela.
# Reason (Selah Sue album)

Reason is the second studio album by the Belgian recording artist Selah Sue. Distributed by Warner Music Group, it was released by Because Music on March 26, 2015.

## Track listing
### Notes and sample credits

denotes co-producer

## Certifications

| Region | Certification | Certified units/sales |
| Belgium (BEA) | Gold | 15,000$^*$ |
| $^*$ Sales figures based on certification alone. |||
In 2016, it was awarded a gold certification from the Independent Music Companies Association, indicating sales of at least 75,000 copies throughout Europe.
# Joe Skladany

Joseph Peter "Muggsy" Skladany (May 25, 1911 – August 9, 1972) was an American football player and coach. He played college football at the University of Pittsburgh, where he was consensus All-American at end in 1932 and 1933. Skladany played professionally for one season, in 1934, with the Pittsburgh Pirates of the National Football League (NFL).
Skladany served as the head football coach at the Carnegie Institute of Technology—now known as Carnegie Mellon University—for one season, in 1943, compiling a record of 0–4–1.
Skladany was found dead on August 9, 1972, at the Penn Harris Hotel in Harrisburg, Pennsylvania. He was inducted into the College Football Hall of Fame as a player in 1975.

## Head coaching record

| Year | Team | Overall |
| Carnegie Tech Tartans (Independent) (1943) ||||||
| 1943 | Carnegie Tech | 0–4–1 |
| Carnegie Tech: | Carnegie Tech: | 0–4–1 |
| Total: | Total: | 0–4–1 |
# Welles-Pérennes

Welles-Pérennes (French pronunciation:) is a commune in the Oise department in northern France.
# Helmut Freitag

Helmut Freitag (born July 1960) is a German pianist, organist, conductor and academic teacher.

## Education

Born in Bad Kreuznach, Freitag studied church music, music school (state examination in history and music) and orchestral conducting (diploma with distinction) in Saarbrücken, Düsseldorf and Geneva. His teachers were André Luy, Lionel Rogg, Jean Micault, Hans Drewanz and Hartmut Schmidt.

## Career

From 1988 to 1991, Freitag directed the music school of the district of Kaiserslautern. Since 1989, he has directed the Kaiserslautern Chamber Orchestra. With this orchestra, he has performed in the US, Scandinavia, Switzerland and Italy. On Easter Monday 1991, he became district cantor of the Protestant deaneries of Kaiserslautern and Otterbach. In 2001, he was appointed Kirchenmusikdirektor. Also, since 1991, he has held a teaching position for vocal correpetition at the Hochschule für Musik und Darstellende Kunst Mannheim. In 2002, he was appointed University Music Director of the Saarland University. In 2006, he was awarded the cultural prize of the city of Bad Kreuznach. In 2007, the Saarland University appointed him honorary professor [de] of musicology.
Freitag is the initiator of the carillon in the Kaiserslautern Collegiate Church, which was installed in 2009 and, with 47 bells, is one of the largest instruments of its kind in Germany. He has performed his solo organ concerts in almost all European countries.
In 2017, Freitag was awarded a Doctorate (Dr. phil.) with the dissertation Komponisten der Naheregion:Gerhard Fischer-Münster, Fridel Grenz, Magdalene Schauss-Flake, Dieter Wellmann. Studien zur regionalen Kirchenmusik unter besonderer Berücksichtigung der Werke für Orgel.
# Short Sherpa

Two aircraft built by Short Brothers have been named Sherpa:
* Short SB.4 Sherpa, a jet-powered experimental wing research aircraft, first flight 1953
* Short C-23 Sherpa, military version of the Short 330 and 360 turboprop powered transport aircraft, introduced 1985
# Pedro Ferré

Pedro Ferré (29 June 1788 - 21 January 1867) was an Argentine politician and military officer, who served in four terms as Governor of Corrientes Province (1824-1828, 1830-1833, 1839 and the last term between 1839 and 1842) and was constitutional delegate for the redaction of the Argentine Constitution of 1853.
He was elected National Senator and was designated provisional president of the Senate between 1864 and 1865.