OpenLLM-France/wikimedia huggingface dataset:
# F15845

F15845 is a cardiac drug proposed to have beneficial effects for the treatment of angina pectoris, arrhythmias and ischemia by inhibiting the persistent sodium current. The drug, currently in phase II of clinical trials, targets the persistent sodium current with selectivity and produces minimal adverse effects in current experimental studies.

## Persistent sodium current

In the cardiac myocyte, the persistent sodium current corresponds to the delayed inactivation of the major sodium channel Nav1.5. In a functional muscle cell, this sodium channel plays an important role in the propagation of an action potential through the heart. Sodium influx is a key component in the initial depolarisation of the cell, followed by quick inactivation to allow for a plateau phase and calcium influx. Persistent sodium current prevents this normal action potential pattern, resulting in a prolonged action potential and increased sodium levels within the cardiac myocyte. Under these conditions the heart is more susceptible to damage and malfunctions. Inhibition of the persistent sodium current is a novel therapeutic target to prevent long term changes in the heart resulting from ischemia. Hypoxia, heart failure and oxygen derived free radicals are all factors believed to activate the persistent sodium current. In ischemia, the major damage to the cardiac myocyte, due to hypoxia, is seen following the reperfusion of blood. High intracellular sodium levels from the persistent current results in high influx of calcium during reperfusion; leading to calcium overload, hypercontraction and cardiac myocyte death. The main contributor to this calcium overload is the sodium/calcium exchanger working in reverse, driven by the high intracellular concentration of sodium exchanging out of the cell with the extracellular calcium moving in.

## Pharmacology

F15845 has been shown to selectively inhibit the persistent sodium current of Nav1.5 exerting cardioprotective effects following ischemia. In vitro testing showed minimal effects of F15845 on other important ion channels of the heart, including major Ca2+ and K+ channels. This characteristic is thought to account for the limited effect of F15845 to change other heart parameters such as basal cardiac function, hemodynamic functions and ventricular fibrillation. F15845 was also shown to exert improved effects when the membrane potential was depolarized, by acting on the extracellular side of the channel. This effect of the F15845 on the depolarised state of the persistent sodium current renders the drug particularly useful in ischemic conditions when the cardiac cell is depolarised.

## F15845 and angina

The F15845 drug has been developed as a potential drug for therapy of angina pectoris. Current anti-anginal drugs, aiming to prevent ischemic events resulting from angina, fail to completely relieve symptoms without further cardiovascular effects (Vacher et al., 2009). In addition to F15845 being more selective to the persistent sodium current compared to its counterparts, it has also been shown to inhibit ST segment changes in the canine model of angina.
# Universal Typeface Experiment

The Universal Typeface Experiment was a promotional website funded by Bic, the maker of the Bic pen. The website crowdsourced a typeface with mobile users who entered their handwriting on the website using a touchpad and the then newly updated BIC pen called the Cristal Stylus, which included a touchpad-friendly rubber tip.
Though it was possible to participate using one's fingers, writing with a pen was significantly easier. Notwithstanding this difference, the website offered the contributor the opportunity to sign in and answer some demographic questions, enabling automatic aggregation of statistics about handwriting that sparked an article in the Smithsonian magazine. The downloadable font created by this averaged handwriting experiment was heavily influenced by the user prompt, whereby the user was presented with 26 capital letters in random order in the Arial font. Within the confines of this self-selection bias, regional differences were easily recognizable.
The website, hosted by Tribal DDB and developed by the Dutch ad agency MediaMonks, was originally intended as a product launch and was scheduled to be taken down in August 2014. It won the "Site of the Month" award by the Favourite Website Awards (FWA) and was still live and accepting contributions in January 2015.
# Vokesimurex recurvirostris

Vokesimurex recurvirostris, common name : the bent-beak murex, is a species of sea snail, a marine gastropod mollusk in the family Muricidae, the murex snails or rock snails.

## Description

The shell size varies between 36 mm and 88 mm
This is a comparatively small species, rarely exceeding two inches (5.08 cm) in length. The varices are thick, plait-like and tuberculated by the crossing of elevated lines which also cut the three inter-variceal ribs into tubercles. These tubercles are sometimes developed into short spines, one on the upper part of each varix, and there are also one or two on each varix below the aperture. The color varies from whitish to livid with two or three broad brown bands which are most visible within the aperture.

## Distribution

This species occurs in the Pacific Ocean off Mexico to Ecuador.
# Nottingham English School

Nottingham English School is a specialist provider of English language tuition based in the city of Nottingham in England. The School is an academic department forming part of Nottingham College, based at the historic Adams Building in the Lace Market area of Nottingham city centre.
The Nottingham English School offers English language training including:
* General English
* Academic English
* Preparation for the IELTS test
* Summer School programmes
* CELTA teacher training programmes
* Bespoke study opportunities for groups
The Nottingham English School offers British Council-accredited English Language tuition and is a member of English UK. Nottingham College is licensed to sponsor migrants by the UK Visas and Immigration under Tier 4 of the British points-based immigration system.
# Hunter 146

The Hunter 146 is an American sailing dinghy that was designed by Chuck Burns and the Hunter Design Team as a novice sailboat and first built in 2003.
The design was renamed the Hunter 15 in 2008 and is now referred to as the Marlow-Hunter 15.

## Production

The design has been built by Hunter Marine in the United States, starting in 2003 and remains in production under the designation Marlow-Hunter 15.

## Design

The Hunter 146 is a small recreational dinghy, built predominantly of ACP. It has a fractional sloop rig, a raked stem, an open reverse transom, a transom-hung rudder controlled by a tiller and a retractable centerboard. It displaces 340 lb (154 kg) and can accommodate up to four people.
The boat has a draft of 3.00 ft (0.91 m) with the centreboard extended and 0.50 ft (0.15 m) with it retracted, allowing beaching or ground transportation on a trailer.
# Norwich City (disambiguation)

Norwich City is an English professional football club.
Norwich City may also refer to:
* Norwich, the city in Norfolk, England
* Norwich City, an English former railway station
* Norwich City Council, the local authority for the city of Norwich, England
* Norwich City L.F.C., an English women's football club
* SS Norwich City, a British merchant ship built in 1911
# Norway at the 1976 Summer Paralympics

Norway sent a delegation to compete at the 1976 Summer Paralympics in Toronto, Canada. Its athletes finished sixteenth in the overall medal count.

## Medalists

| Medal | Name | Sport | Event |
| Gold | Casper Caspersen | Archery | Men's tetraplegic round A-C |
| Gold | Jarle Johnsen | Athletics | Men's long jump A |
| Gold | Reidun Laengen | Athletics | Women's 100m B |
| Gold | Reidun Laengen | Athletics | Women's long jump B |
| Gold | Erling Trondsen | Swimming | Men's 100m freestyle C1 |
| Gold | Idar Hunstad | Swimming | Men's 100m breaststroke B |
| Gold | Erling Trondsen | Swimming | Men's 100m butterfly C1 |
| Gold | Erling Trondsen | Swimming | Men's 200m individual medley C1 |
| Gold | Bente Gronli | Swimming | Women's 50m backstroke 4 |
| Silver | Oddbjorn Stebekk | Archery | Men's FITA round tetraplegic A-C |
| Silver | Karlsen | Archery | Women's advanced metric round open |
| Silver | Jarle Johnsen | Athletics | Men's 60m A |
| Silver | L. Larsen | Athletics | Men's 1500m F |
| Silver | Terje Hansen | Athletics | Men's javelin throw B |
| Silver | Hans Anton Aalien | Swimming | Men's 100m breaststroke A |
| Bronze | O. Holen | Archery | Women's advanced metric round open |
| Bronze | Jarle Johnsen | Athletics | Men's high jump (two foot take off) A |
| Bronze | Idar Hunstad | Athletics | Men's javelin throw B |
| Bronze | Casper Caspersen Jan Erik Stenberg | Table tennis | Men's doubles 1A |
# Notocrater youngi

Notocrater youngi is a species of small sea snail, a marine gastropod mollusk in the family Pseudococculinidae, the false limpets.

## Distribution

This species occurs in the Atlantic Ocean off the Bahamas; and at the Caribbean coast of Colombia.

## Description

The maximum recorded shell length is 3.14 mm.

## Habitat

Minimum recorded depth is 70 m. Maximum recorded depth is 518 m.
# Humin, Palpa

Humin is a village development committee in Palpa District in the Lumbini Zone of southern Nepal. At the time of the 1991 Nepal census it had a population of 3191 people living in 325 individual households.
# Hungarian school of violin playing

The Hungarian violin school started with Jòzsef Joseph Böhm, when in 1819 he began to teach the first violin class of Vienna's Conservatory. Böhm studied in Budapest, with his father, and with Pierre Rode (probably when he was in Russia), so he is the link between the French school (an evolution of the Italian school through Viotti) and the Hungarian one.

## Böhm's classes

Böhm's classes gave birth to the following Hungarian violinists: Joachim, Grün, Auer, Flesch, (Tivadar Nachez), Hubay; and to violinists of other nationalities as: Hellmesberger, Jacob Dont, Ernst, Ferdinand Laub, Franz Kneisel and Karl Klingler. The importance: Joachim will teach in Berlin, Auer in Russia and in America, Flesch in Switzerland and England, Hellmesberger and Dont in Vienna, Hubay in Brussels and Budapest, Laub in Russia, Klingler in Germany and Kneisel in America. Among the violinists who were pupils in the Budapest academy, created by Hubay, we find: Tibor Varga (director of Sion academy), André Gertler (head of string-department in Brussels), Joseph Szigeti (head of string-department in Budapest), Sandor Vegh (director of the Mozarteum), Ilona Feher (teacher of Shlomo Mintz in Tel Aviv), Oskar Back (founder of Amsterdam's school), Béla Katona. Someone will perhaps have heard about Kato Havas, Géza Szilvay, Paul Rolland, Robert Gerle or Shinichi Suzuki. The first four have studied in Budapest academy in the same cultural atmosphere and with the same technique. Suzuki studied in Berlin with Klingler (Joachim's pupil). These violinists are mentioned because of their fame, but they are part of a long list of key-persons in world musical life coming from the Hungarian school. the way from Karl Klingler also leads to Alphonse Brun, Alfred Ellenberger in Switzerland.
Kato Havas is author of the book "Stage fright" in which all the problems of posture are faced. Sensitive to these problems, Rolland has created the violin school system in the U.S. and collaborated with F. Matthias Alexander. Silvay organized the string-department in Helsinki "Sibelius" academy. Gerle collaborated with Rolland and Havas and worked in U.S. It must be told that in Budapest academy there is a violin pedagogy class since the year of its foundation in 1875. Since then it is collecting the elements of the violin playing tradition and those of researchers. Very big importance is given to pedagogy and to its diffusion.
# Hydrostone

Hydrostone is a neighbourhood in the North End of the Halifax Peninsula in the Halifax Regional Municipality, Nova Scotia, Canada. It consists of ten short parallel streets and is bordered by Duffus Street to the north, Young Street to the south, Isleville Street to the west and Novalea Drive to the east. The Hydrostone District has about 9.3 ha (23 acres) of landmass.
The neighbourhood was designed by architect Thomas Adams to provide housing for working-class families displaced by the Halifax Explosion in 1917. Architectural design was by George Ross of the Montreal architectural firm of Ross and Macdonald. The neighbourhood draws its name from the special cinderblocks from which the houses were constructed. Most of the dwellings are row-houses in groups of four and six, except for the large, two-storey single-family houses at the eastern end of each street. Some have been converted to sets of flats.
All of the streets in the Hydrostone are boulevards except Stanley Place. These boulevards have treed, grassy strips which serve as communal outdoor space for the neighbourhood. This is consistent with the Garden city movement by which Adams was influenced. All streets are also served by back lanes, a feature characteristic of Western Canadian cities, but not usually found in Eastern Canadian communities.
It is designated a National Historic Site of Canada.

## Construction

Following the Halifax Explosion, many of the wood-frame buildings collapsed on their coal stoves and furnaces and caught on fire, which was a concern when reconstruction was being planned. To minimize the danger of fire, Adams and Ross proposed the use of non-combustible hydrostone for the reconstruction of this area.
Hydrostone was a concrete block that was finished with crushed rock (granite, in this case) to approximate the appearance of cut-stone construction. The concrete blocks and their faces were amalgamated through a hydraulic pressing process, patented by a Chicago firm. Manufacture of the blocks was done in a plant located in Eastern Passage and the finished stones were hauled across Halifax Harbour by barge.
Transporting the stones to the construction site was problematic, due to the steep rise from the harbour. To solve this problem and make the area more easily accessible, two diagonal streets were included in the Richmond district reconstruction plans: Devonshire Street / Avenue and Dartmouth Avenue.

## The Hydrostone today

Today, the Hydrostone has become a gentrified area, sought after by young professionals and small families for its ample green space and proximity to shops and transit. Recently, this newer generation has been buying and renovating the area's homes, pushing up property values and displacing longtime residents.
In 2011, the Canadian Institute of Planners named the Hydrostone the Second Greatest Neighbourhood in its inaugural Great Places in Canada contest.
# Hymenopodidae

Hymenopodidae is a family of the order Mantodea (mantises), which contains six subfamilies. Some of the species in this family mimic flowers and are found camouflaged among them; these are called flower mantises. Their coloration is aggressive mimicry, luring prey to approach close enough to be seized and eaten.

## Subfamilies, tribes and genera

The Mantodea Species File lists:

### Acromantinae

Auth: Giglio-Tos, 1919
* tribe Acromantini
** Acromantis Saussure, 1870
** Ambivia Stal, 1877
** Citharomantis Rehn, 1909
** Majangella Giglio-Tos, 1915
** Metacromantis Beier, 1930
** Oligomantis Giglio-Tos, 1915
** Parapsychomantis Shcherbakov, 2017
** Psychomantis Giglio-Tos, 1915
** Rhomantis Giglio-Tos, 1915
* tribe Otomantini
** Anasigerpes Giglio-Tos, 1915
** Chrysomantis Giglio-Tos, 1915
** Otomantis Bolivar, 1890
** Oxypiloidea Schulthess, 1898

### Hymenopodinae

Auth: Giglio-Tos, 1919
* tribe Anaxarchini
** Anaxarcha Stal, 1877
** Euantissa Giglio-Tos, 1927
** Heliomantis Giglio-Tos, 1915
** Nemotha Wood-Mason, 1884
** Odontomantis Saussure, 1871
** Werneriana Shcherbakov, Ehrmann & Borer, 2016
* tribe Hymenopodini
** Chlidonoptera Karsch, 1892
** Chloroharpax Werner, 1908
** Creobroter (Westwood, 1889)
** Helvia Stal, 1877
** Hymenopus (Serville, 1831)
** Panurgica Karsch, 1896
** Pseudocreobotra Saussure, 1870
** Theopropus Saussure, 1898

### Oxypilinae

Auth: Giglio-Tos, 1919
* tribe Hestiasulini
** Astyliasula Schwarz & Shcherbakov, 2017
** Catestiasula Giglio-Tos, 1915
** Ephestiasula Giglio-Tos, 1915
** Hestiasula Saussure, 1871
** Pseudohestiasula' Schwarz & Shcherbakov, 2017
* tribe Oxypilini
** Ceratomantis Wood-Mason, 1876
** Junodia Schulthess-Rechberg, 1899
** Oxypilus Serville, 1831
** Pachymantis Saussure, 1871
** Pseudoxypilus Giglio-Tos, 1915

### Phyllocraniinae

Africa:
* Phyllocrania Burmeister, 1838

### Phyllothelyinae

South-East Asia:
* tribe Parablepharini
** Parablepharis Saussure, 1870
* tribe Phyllothelyini
** Ceratocrania Westwood, 1889
** Phyllothelys Wood-Mason, 1877

### Sibyllinae

Africa:
* Leptosibylla Roy, 1996
* Presibylla Bolivar, 1908
* Sibylla Stal, 1856
NB: The Epaphroditinae Giglio-Tos, 1915 (from the Caribbean) are now placed in a separate family Epaphroditidae.

## Gallery

* Sudanese Hymenopodid Mantis, Pseudocreobotra species
* Adult female Chlidonoptera vexillum
* Adult female Pseudoharpax virescens
* Adult female Creobroter species from West Java
* Adult female Pseudocreobotra wahlbergii
* Adult male Creobroter gemmatus
* Dead adult female C. gemmatus
* Adult female Acromantis japonica
* Adult female Ephestiasula species
* Four dead adult female Hymenopus coronatus
* Dead adult male Hymenopus coronatus
* Subadult female Hymenopus coronatus head
* Subadult female H. coronatus
* Subadult female H. coronatus eating
* Adult female pakyulisis titinggalit
* Subadult female Phyllocrania paradoxa
* Two adult female P. paradoxa
* Subadult female P. paradoxa
* Male Phyllocrania paradoxa, probably subadult
* Adult female Hestiasula brunneriana
* Pseudocreobotra ocellata nymph
# Hymenophyllum wilsonii

Hymenophyllum wilsonii, the Wilson's filmy-fern, is a small, fragile, perennial leptosporangiate fern which forms large dense colonies from creeping rhizomes.

## Distribution

Confined to western Europe (Britain, Ireland, France, Norway, Spain and The Faeroes) and Macaronesia.

## Gallery

* Detail of Hymenophyllum wilsonii fronds. Indusia are present.
* Hymenophyllum wilsonii colony.
* Hymenophyllum wilsonii habitat. Near Kendal, Cumbria, England.
# Northwest Kainji languages

The six Northwest Kainji languages, also known as the Lela languages or the Duka languages, are spoken near Kainji Lake on the Niger River in Nigeria. They are distinguishable from other Kainji languages by the reduction of their noun-class prefixes to single consonants.

## Classification
### Blench (2018)

Northwest Kainji classification by Blench (2018):
* Northwest Kainji
** ? Damakawa
*** cLela
*** Hun-Saare
*** Ma'in, Wurə-Gwamhyə-Mba
The position of Damakawa is uncertain.

### Blench (2010)

In Blench (2010), Lela (C'lela and Ribah) is divergent from the other languages, though poorly attested Damakawa has similarities.
* Northwest Kainji
** Lela (C'lela), ? Damakawa
*** Gwamhi-Wuri
*** ut-Ma'in (Fakai), Hun-Saare (Duka)
# Now I'm Nailed to Your Bedroom Wall, I've Only Got Myself to Blame

Professional ratings :
| Review scores ||
| Source | Rating |
| Rock Sound | |
Now I'm Nailed to Your Bedroom Wall, I've Only Got Myself to Blame is a compilation album by London-based glam rockers Rachel Stamp. It was released in April 2009 via Serena/Cargo Records. The album takes its name from the lyrics of the Rachel Stamp song, "Pink Skab".

## The Album

Released April 27, 2009 on CD & Digital Download (SRCD 9001)

## Track listing

The tracks chosen for the compilation were selected by David Ryder-Prangley. The album was mixed, edited and mastered by Drew Richards with sleeve notes written by Simon Price. Originally, the album was to be released with a bonus DVD, but after reviewing the material, the band have decided to release the DVD separately later this year. The album features many rare tracks such as "Dead Girl" (which was only available on a free CD given away with Kerrang! magazine and the band's Sweet Shop compilation CD) and "Every Night I Pray for the Bomb" (which was only available on the "Bring Me the Head of Rachel Stamp EP")

### CD version

* Black Cherry (album version)
* Queen of the Universe
* Dead Girl
* Hey Hey Michael You're Really Fantastic (single edit)
* My Sweet Rose (single version)
* I Like Girlz
* I Got the Worm
* Do Me In Once and I'll Be Sad, Do Me In Twice and I'll Know Better (radio edit)
* Black Tambourine
* Monsters of the New Wave
* True Love
* Twisted
* Les Oceans De Venus
* I Wanna Be Your Doll
* Every Night I Pray for the Bomb
* Pink Skab
* Jet Black Supersonic
* Stealing Clothes From Shelley Barrett
* Witches of Angelholm
* Didn't I Break My Heart Over You (radio edit)

### Digital download

The digital download version of the album replaces "Hey Hey Michael You're Really Fantastic" and "Every Night I Pray for the Bomb" with "Home Made Sex Change" and "Creeps". "Home Made Sex Change" was given away as a free download on the band's official website in 2002 and "Creeps" was available as a free track on a Metal Hammer compilation CD, given away with a copy of the magazine in November, 2004.
* Black Cherry (album version)
* Queen of the Universe
* Dead Girl
* My Sweet Rose (single version)
* I Like Girlz
* I Got the Worm
* Do Me In Once and I'll Be Sad, Do Me In Twice and I'll Know Better (radio edit)
* Black Tambourine
* Monsters of the New Wave
* True Love
* Twisted
* Les Oceans De Venus
* I Wanna Be Your Doll
* Pink Skab
* Jet Black Supersonic
* Stealing Clothes from Shelley Barrett
* Witches of Angelholm
* Didn't I Break My Heart Over You (radio edit)
* Home Made Sex Change
* Creeps

## Production and promotions

To promote the release, Rachel Stamp reformed for a sold out, one off show at the O2 Islington Academy, London on April 10, 2009.