OpenLLM-France/wikimedia huggingface dataset:
# GTP cyclohydrolase I

GTP cyclohydrolase I (GTPCH) (EC 3.5.4.16) is a member of the GTP cyclohydrolase family of enzymes. GTPCH is part of the folate and biopterin biosynthesis pathways. It is responsible for the hydrolysis of guanosine triphosphate (GTP) to form 7,8-dihydroneopterin triphosphate (7,8-DHNP-3'-TP, 7,8-NH$_2$-3'-TP).

## Gene

GTPCH is encoded by the gene GCH1. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all of the variants give rise to a functional enzyme.

## Clinical significance

At least 94 disease-causing mutations in this gene have been discovered. Mutations in this gene are associated with two disorders: autosomal recessive GTP cyclohydrolase I deficiency and autosomal dominant GTP cyclohydrolase I deficiency. These may present with malignant phenylketonuria (PKU) and hyperphenylalaninemia (HPA) and lead to a lack of certain neurotransmitters (dopamine, norepinephrine, epinephrine and serotonin). The dominant form, with mutation in only one of the two alleles for GTP cyclohydrolase I, causes dopamine-responsive dystonia, characterized by childhood-onset dystonia. Patients with the recessive form have mutations in both alleles for GTP cyclohydrolase I. Patients present with developmental delays and neurological dysfunction with trunk hypotonia, hypertonia of the extremities, abnormal movements, tremors, convulsions, and sometimes autonomic dysfunction. Response to treatment is variable and the long-term and functional outcome is unknown. To provide a basis for improving the understanding of the epidemiology, genotype/phenotype correlation and outcome of these diseases their impact on the quality of life of patients, and for evaluating diagnostic and therapeutic strategies a patient registry was established by the noncommercial International Working Group on Neurotransmitter Related Disorders (iNTD).

## Function

The transcribed protein is the first and rate-limiting enzyme in tetrahydrobiopterin (THB, BH$_4$) biosynthesis, catalyzing the conversion of GTP into 7,8-DHNP-3'-TP. THB is an essential cofactor required by the aromatic amino acid hydroxylase (AAAH) and nitric oxide synthase (NOS) enzymes in the biosynthesis of the monoamine neurotransmitters serotonin (5-hydroxytryptamine (5-HT)), melatonin, dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), and nitric oxide (NO), respectively.
GTPCH (GCH1) and tetrahydrobiopterin were found to protect against cell death by ferroptosis. Tetrahydrobiopterin (BH$_4$) acts as a potent, diffusable antioxidant that resists oxidative stress and enables cancer cell survival.
# Tomskiy Khutor

Tomskiy Khutor is a village located in the Kharmang District of Gilgit-Baltistan, Pakistan. The Pakistani Air Force has a base here.
# Vera Hatz

Vera Hatz (1923 - 2010) was a German numismatist, who specialised in medieval European coinage, in particular that of the tenth and eleventh centuries in northern Europe. She was jointly awarded the Royal Numismatic Society Medal, as well as the Gunnar Holst Medal.

## Biography

Born Vera Jammer on 15 August 1923 in Hamburg, she was awarded her PhD from the University of Hamburg. Entitled "Die Anfänge der Münzprägung im Herzogtum Sachsen. (10. und 11. Jahrhundert)", it was supervised by Walter Hävernick (de) and published in 1952. By 1951 she had begun work in the numismatic department at the Museum for Hamburg History. In 1954 Hatz became part of an international collaborative project 'Corpus Nummorum Saeculorum IX-XI qui in Suecia Reperti Sunt' alongside Peter Berghaus, Michael Dolley, Ulla S. Linder-Welin and Brita Malmer. A further collaborator was her husband Gert Hatz. She was also known for her work on the Otto-Adelheid coinage.
In 1988 the festschrift Commentationes numismaticae 1988: Festgabe für Gert und Vera Hatz was published. The volume recognised the important contributions both made to numismatics, and in particular coinage of the Viking world.
In 2013 a medal was designed by Peter-Götz Güttler, posthumously commemorating Hatz's 90th birthday.

## Awards

* Royal Numismatic Society Medal - 2003 (with Gert Hatz)
* Gunnar Holst Medal - 2007 (with Gert Hatz)
# Wilbert Das

Wilbert Das (born 2 December 1963) is a Dutch fashion designer.

## Biography

Wilbert Das spent his formative years working on his parents dairy farm in the small village of Riethoven in the southern Netherlands. At age 19, he left Riethoven to study fashion design at the Academy of Fine Arts in Arnhem, where he received his diploma in 1988. Das was intrigued by the revolution that was taking place in Italian fashion; after graduating from Arnhem, Das travelled to Italy for an interview with clothing manufacturer Renzo Rosso, the owner of the fashion brand Diesel. Das was offered a job on the spot. In fact, he started working at Diesel that day in the role of assistant male designer on the Male, Accessories, Leather and Kids lines; he was soon directing the style office. In 1993, Das was recognized with the title of Creative Director.

## Collection Design

During Das' early years with Diesel, the company became most famous for its denim collections. Throughout this time, Diesel used many techniques to age jeans and give them a more vintage feel; this included experimenting with dyes, destruction, movement of pockets, reshaping and introduction of curves.
In subsequent years, and under Das's creative direction, Diesel introduced collections of footwear, eyewear (Diesel Shades), jewellery (Diesel Jewellery), and watches (Diesel Timeframes).

## Communications & Advertising

As well as being responsible for the development of all Diesel's fashion and accessories collection, in his role as Creative Director, Das also oversaw the creative aspects of every Diesel campaign from the time the company began advertising until 2009. The influence of Diesel's communications campaigns, published under the umbrella label “For Successful Living”, have won Diesel and Das the Grand Prix, Gold, and ‘Advertiser of the Year’ awards at the International Festival of Advertising at Cannes.
# Usutuaije Maamberua

Usutuaije Maamberua (born 5 August 1957) is a Namibian politician. He was the president of the South West Africa National Union (SWANU) from 2007 until 2017. Maamberua has served in the National Assembly of Namibia since 2010.

## Early life and education

Born in 1957 in Tsumeb, Maamberua earned three Master of Arts degrees (from the University of Namibia, Heriot-Watt University and the University of Southampton) and one Ph.D. (University of the Witwatersrand) in business and economics related fields.

## Politics

An accountant by training, Maamberua worked as the permanent secretary of the Ministry of Finance from 1997. In 2003, he was demoted to the Ministry of Prisons and Correctional Services. Shortly after receiving the demotion, Maamberua resigned to pursue other career opportunities. He became head of the accounting department at the University of Namibia in 2007.
Maamberua was elected to the National Assembly in the November 2009 general election. Meanwhile, as SWANU's presidential candidate, Maamberua received 2,968 votes, which placed him eighth out of twelve candidates. He was re-elected to the National Assembly in the November 2014 parliamentary election; he was again the only SWANU candidate to win a seat.
# Gypsochares kyraensis

Gypsochares kyraensis is a moth of the family Pterophoridae that is found in Russia (the South Siberian Mountains).
# Van Dyks Bay

Van Dyks Bay is a settlement in Overberg District Municipality in the Western Cape province of South Africa.
# Felicity's Wood

Felicity's Wood is a woodland in Leicestershire, England, near the village of Woodhouse Eaves. It covers a total area of 8.77 hectares (21.67 acres). It is owned and managed by the Woodland Trust.
# Norman Sperling

Norman Sperling (born March 19, 1947) is an author, editor, publisher, teacher, and telescope designer living in San Mateo, California.
Sperling received a BA from Michigan State University after graduating from Montgomery Blair High School in Silver Spring, Maryland. He followed that with an MA in History of Science from the University of California, Berkeley. He has taught astronomy and related courses at Sonoma State University, California State University, Hayward, UC Berkeley, and San Francisco State University.

## Publisher and author

Sperling founded astronomical supplier and publisher Everything in the Universe in 1977. He has been assistant editor for Sky & Telescope magazine and was science editor for AltaVista. As of 2011, Sperling is the editor and publisher of the Journal of Irreproducible Results, a science humor magazine. He authored What Your Astronomy Textbook Won't Tell You and Any Parent's Recipe for Great Baseball He edited and published John Dobson's book How and Why to Make a User-Friendly Sidewalk Telescope. He has also been published in Academic American Encyclopedia, Encyclopedia Americana online, Technology Review, San Francisco Examiner, Astronomy, Pacific Discovery, Journal of College Science Teaching, Mercury, Rittenhouse, Popular Astronomy, Telescope Making, Griffith Observer, Reflector, and The Pundit.
Sperling created the Catalog of North American Planetaria (CATNAP), which later expanded into the Planetarium Directory. He has been planetarium director at Duncan Planetarium, Princeton Day School, New Jersey; Rotary-Chabot Planetarium, Chabot Observatory and Science Center, California; and Edgewood Junior High School Planetarium, Maryland, and he has been a lecturer at Morrison Planetarium in San Francisco.

## Inventor

As an inventor, Sperling, with Mike Simmons, created the Astroscan telescope for Edmund Scientific, as well as "The Stars Above" star-finder for Spherical Concepts.

## Expert witness

Sperling serves occasionally as an expert witness in the field of astronomy. The most high-profile case in which he testified was known as the Billionaire Boys Club case in 1992. He was able to nullify the testimony of a key prosecution witness. The defendant was acquitted.

## Volunteer service

Norman Sperling is a recipient of the National Service Award by the Western Amateur Astronomers, and had been recognized "For special and meritorious service for his unusual dedication and service to the astronomical community in all areas of astronomy" by the Astronomical Association of Northern California. He is a Fellow of the International Planetarium Society (first induction).
Sperling is active in the Bay Area Skeptics, Northern California Historical Astronomy Luncheon and Discussion Association.
# Valgjärve

Valgjärve is a village in Kanepi Parish, Põlva County in southeastern Estonia.
# If... (The Bluetones song)

"If..." is a song by The Bluetones, released as the second single from their second album, Return to the Last Chance Saloon, in 1998. It reached number thirteen on the UK Singles Chart.
In 2006, it was included on the band's two-disc compilation album, A Rough Outline: The Singles & B-Sides 95–03.

## Track listing
### CD

* "If..."
* "Blue Shadows"
* "The Watchman"

### 7" / Cassette

* "If..."
* "Blue Shadows"

## Trivia

The title and font are a reference to the 1968 film if.....
# IfMUD

ifMUD is a MUD associated with the rec.arts.int-fiction newsgroup accessible via telnet or a MUD client. It is central to the interactive fiction community, frequented by many of the genre's best-known writers. Every year, the XYZZY Awards are hosted on ifMUD during an online ceremony.
ifMUD was founded in 1997 by Liza Daly. It is written in the Perl computer programming language making use of an extensive hack of the earlier PerlMUD, with many additional features.

## Game characteristics

ifMUD is organized into areas, with a distinct area usually the work of a particular contributor or group of contributors and having its own interactive fiction plot. For example, Save Princeton was created by Jacob Weinstein and Karine Schaefer.

## Innovations

The tradition of SpeedIF, in which short interactive fiction works, created around story prompts, are developed and shared in a two-hour timeframe, was originated on ifMUD by David Cornelson.

## MUD bots

Two major bots exist on ifMUD, Alex and Floyd.
Floyd acts as an interpreter for many different IF writing platforms. It was named after a fictional character from the Planetfall game by Infocom.
Alex, a "parrot" bot named after Alex Pepperberg, keeps track of memos on any topic, editable by anyone, similar to a wiki. It was written by Dan Shiovitz and was inspired by the Perl infobot Purl.

## Reception

ifMUD has, at times, simultaneously been praised for its service to the interactive fiction community and criticized for fostering an excessively self-referential, socially impenetrable environment.
Its userbase has been described as a "small but friendly multinational tribe".
# Olle Andersson (speedway rider)

Anders Olof Andersson also known as Olle Andersson (1932–2017) was an international speedway rider from Sweden.

## Speedway career

Andersson reached the final of the Speedway World Championship in the 1956 Individual Speedway World Championship.
After visiting the United States in 1957 he emigrated to the United States the following year.

## World Final Appearances
### Individual World Championship

* 1956 - London, Wembley Stadium - 14th - 2pts
# Idlewild Blue (Don'tchu Worry 'Bout Me)

"Idlewild Blue (Don'tchu Worry 'Bout Me)" is the third single released from American musical duo OutKast's sixth studio album, Idlewild, and the first from the album that is sung by André 3000. Andre also plays the guitar for the song, using the standard 12-bar blues. The song tells the story of a character wishing to gain his independence by leaving the familiarity of his family, friends and town. The video shows Andre and the band playing in an old house during a thunder storm, with people dancing around him. The building slowly fills with rain water, and by the end of the video, everything in the house is underwater. Because of the proximity in which the video was filmed, some viewers interpret the video to be a visual allusion to the New Orleans flooding following Hurricane Katrina, while others think the water represents the "blues" that can flood over someone's life. The end of the video features a text that reads, "Dedicated to all those tryin' to stay afloat."

## Track listings
### CD single

* "Idlewild Blue (Don'tchu Worry 'Bout Me)" – 3:24
* "She Lives in My Lap" (featuring Rosario Dawson) – 4:29

### Promo

* "Idlewild Blue (Don'tchu Worry 'Bout Me)" (main version) – 3:24
* "Idlewild Blue (Don'tchu Worry 'Bout Me)" (clean version) – 3:24
* "Idlewild Blue (Don'tchu Worry 'Bout Me)" (instrumental) – 3:24

## Charts

Weekly chart positions for "Idlewild Blue (Don'tchu Worry 'Bout Me)" :
| Chart (2006) | Peak position |
| Romania (Romanian Top 100) | 71 |
| US Billboard Hot 100 | 100 |
| US Pop 100 (Billboard) | 80 |
# Old Style common year starting on Saturday

This is the calendar for any Old Style common year starting on Saturday, 25 March. The Old Style calendar ended with the following March, on 24 March. Examples: Julian year 1301, 1413 or 1514 (see bottom tables).
A common year is a year with 365 days, in other words, not a leap year, which has 366.
| January (prior year) Su Mo Tu We Th Fr Sa 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 | February (prior year) Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 | March Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 |
| April Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 | May Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 | June Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 |
| July Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 | August Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 | September Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 |
| October Su Mo Tu We Th Fr Sa 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 | November Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 | December Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 |
| January (year end) Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 | February (year end) Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 | March (new year) Su Mo Tu We Th Fr Sa   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 |
| Millennium | Century | Old Style Year | Old Style Year | Old Style Year | Old Style Year | Old Style Year | Old Style Year | Old Style Year | Old Style Year | Old Style Year | Old Style Year | Old Style Year |
| 2nd Millennium: | 13th century: | 1206 | 1217 | 1223 | 1234 | 1245 | 1251 | 1262 | 1273 | 1279 | 1290 |
| 2nd Millennium: | 14th century: | 1301 | 1307 | 1318 | 1329 | 1335 | 1346 | 1357 | 1363 | 1374 | 1385 | 1391 |
| 2nd Millennium: | 15th century: | 1402 | 1413 | 1419 | 1430 | 1441 | 1447 | 1458 | 1469 | 1475 | 1486 | 1497 |
| 2nd Millennium: | 16th century: | 1503 | 1514 | 1525 | 1531 | 1542 | 1553 | 1559 | 1570 | 1581 | 1587 | 1598 |
| 2nd Millennium: | 17th century: | 1609 | 1615 | 1626 | 1637 | 1643 | 1654 | 1665 | 1671 | 1682 | 1693 | 1699 |
| 2nd Millennium: | 18th century: | 1710 | 1721 | 1727 | 1738 | 1749 | 1755 | 1766 | 1777 | 1783 | 1794 |
# Iffley Halt railway station

Iffley Halt railway station was built by the Great Western Railway to serve Iffley, a suburb of Oxford; it was actually in Kennington, and not in Iffley.
The station was situated at the western end of Kennington Railway Bridge, which crosses the River Thames. Access from Iffley was via the River Thames towpath, which has a footbridge over Hinksey Stream close to this point. It was opened on 1 February 1908 along with four other halts on the former Wycombe Railway route between Oxford and Wheatley.
Services were provided by steam railmotors based at Oxford, which was also the western terminus; the eastern terminus of these services was Wheatley, Thame or Princes Risborough. When the railmotor services were withdrawn on 22 March 1915, the halt closed. The line remained open for through passenger services, but these did not call at Iffley Halt.

## Route

vteRailways around Oxford :
Legend :
| Preceding station | Disused railways | Following station |
| Abingdon Road Halt | Great Western Railway 1908-1915 | Littlemore |
# Olenelloidea

The Olenelloidea are a superfamily of trilobites, a group of extinct marine arthropods. They lived during the late Lower Cambrian and species occurred on all paleocontinents.

## Taxonomy

Palmer and Repina assigned Gabriellus and Callavia to the Olenelloidea, but the ocular lobes in these two genera circumscribe the entire lateral border of the frontal lobe of the glabella, and thus, do not belong to this superfamily, but to the Judomioidea. Geyer assigned Cambropallas to the Olenelloidea, but it lacks the diagnostic features and appears to be closely related to Andalusiana, and is now considered to be an advanced member of the Nevadioidea.

## Distribution

In western Laurentia Fallotaspididae and Archaeaspididae proceed the first Olenelloidea. The Holmiidae occur at the late Atdabanian, and are contemporary with the Nevadioidea. They are followed by Biceratopsidae and Olenellidae.

## Description

As with most early trilobites, the Olenelloidea have an almost flat exoskeleton, that is only thinly calcified, and has crescent-shaped eye ridges. As part of the Olenellina suborder, the Olenelloidea lack dorsal sutures. The superfamily can be distinguished from all other Olenellina by features of the cephalon and in particular the glabella. The backward portion of the third lateral lobe of the glabella counted from the back (L3) bulges laterally relative to the first lateral lobe (L1). The front end of the eye lobe (or ocular lobe) is connected only to the back half of the frontal lobe (AL or L4) of the glabella, and merges smoothly with it (rather than merely contacting it). The ocular lobe consists of an inner and outer band.
# Oldham Metrolink station

Oldham Metrolink station may refer to:

## Metrolink tram stops

* Oldham Mumps tram stop, a station on Greater Manchester's Metrolink system which opened in 2014
* Oldham Central tram stop
* Oldham King Street tram stop
* Westwood tram stop

## Historic railway stations

* Oldham Central railway station
* Oldham Werneth railway station
* Clegg Street railway station
* Glodwick Road railway station
# Oldham Local Studies and Archives

Oldham Local Studies and Archives holds the archives for the town of Oldham. The archives are held at Union Street, Oldham, and run by Oldham Council. The archives date back to 1597 and include local authority records for the areas of Chadderton, Crompton, Failsworth, Lees, Oldham, Royton and Saddleworth.
# Oldham Methodist Church

The Oldham Methodist Church is a historic church at Main Street and Epton Avenue in Oldham, South Dakota, USA. It was built in 1914 and was added to the National Register in 1987.
It has an L-shaped plan with a bell tower rising from the intersection of its two gables. It was deemed notable as a "rare, practically uncorrupted example" of "the L-shaped form in its pure state. Other original features include Gothic arched window and door openings, decorative bargeboard, hardwood interior appointments and furniture, lighting fixtures, and a pressed-metal ceiling."
# Ikhernofret Stela

The Ikhernofret Stela (Berlin Museum ref 1204) is an ancient Egyptian stela dated to the Middle Kingdom and is notable for its veiled description of how the mysteries of the deity Osiris were carried out in Abydos. The stela is 100 cm high and made of limestone. Osiris is depicted standing under a winged sun disk facing Senusret III. The text is laid out below Osiris in twenty-four horizontal lines. Underneath the text, Ikhernofret, a 12th Dynasty treasurer under Pharaoh Senusret III, is depicted at an offering table with his family. The rituals celebrated the god's kingship, death and resurrection.
The stela describes how Ikhernofret is regarded as a beloved "foster child" of the King who was made "Companion of the King" when twenty-six. He is sent on a mission to Abydos by the King to carry out work in honour of the Kings Father "Osiris, Foremost of the Westerners".
The stela records how the festivities were celebrated in four main parts.
* Procession of Wepwawet ("The Opener of the Ways"). Wepwawet was in this instance a manifestation of the triumphant Horus who came to the aid of his father Osiris. The rite involved excoriation rituals relating to the enemies of Osiris.
* Great Procession. Leaving the Temple of Osiris, a re-enactment of the funeral procession of Osiris in the Neshmet-Barque.
* Haker Festival ("The Night of the Battling Horus"). The acting out of the battle between Horus and Set.
* Procession to the Temple of Osiris. Osiris returns to the Temple, symbolising resurrection and the triumph over death.
The Egyptologist and novelist Christian Jacq used the Ikehernofret inscriptions as the foundation of his Osirian series "The Mysteries of Osiris".