# 2010 Sarasota Open – Singles

James Ward was the defending champion, but he lost against Víctor Estrella in the first round. Kei Nishikori, who played in this tournament as a 'special exempt', won in the final 2–6, 6–3, 6–4, against Brian Dabul.

## Seeds

* Taylor Dent (first round, retired)
* Jesse Levine (quarterfinals)
* Carsten Ball (withdrew due to Davis Cup)
* Brian Dabul (final)
* Kevin Kim (second round)
* Ryan Sweeting (semifinals)
* Donald Young (first round)
* Alex Kuznetsov (second round)
* Robert Kendrick (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| SE | Kei Nishikori | 6 | 6 | | | | | |
| 6 | Ryan Sweeting | 4 | 2 | | | | | |
| 6 | Ryan Sweeting | 4 | 2 | SE | Kei Nishikori | 2 | 6 | 6 |
| | | | | 4 | Brian Dabul | 6 | 3 | 4 |
| 4 | Brian Dabul | 6 | 6 | 4 | Brian Dabul | 6 | 3 | 4 |
| Q | Daniel Garza | 1 | 2 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | T Dent | 6 | 2 | r | | | | | | | | | | | | | |
| | T Smyczek | 2 | 4 | | | T Smyczek | 4 | 3 | | | | | | | | | |
| WC | Vamsee Chappidi | 1 | 1 | | SE | K Nishikori | 6 | 6 | | | | | | | | | |
| SE | K Nishikori | 6 | 6 | | | | | | SE | K Nishikori | 6 | 6 | | | | | |
| | J Witten | 3 | 3 | | | | | | LL | B Rodríguez | 1 | 2 | | | | | |
| LL | B Rodríguez | 6 | 6 | | LL | B Rodríguez | 6 | 6 | | | | | | | | | |
| | V Pospisil | 6$^3$ | 3 | | 5 | K Kim | 2 | 3 | | | | | | | | | |
| 5 | K Kim | 7 | 6 | | | | | | | | | | | SE | K Nishikori | 6 | 6 |
| 9 | R Kendrick | 1 | 5 | | | | | | | | | | | 6 | R Sweeting | 4 | 2 |
| WC | S Bangoura | 6 | 7 | | WC | S Bangoura | 2 | 4 | | | | | | | | | |
| | R DeHeart | 7 | 0 | 0$^r$ | WC | B Reynolds | 6 | 6 | | | | | | | | | |
| WC | B Reynolds | 6$^5$ | 6 | 3 | | | | | WC | B Reynolds | 6$^3$ | 6 | 3 | | | | |
| | J Baker | 6$^1$ | 6 | 6 | | | | | 6 | R Sweeting | 7 | 3 | 6 | | | | |
| WC | M Venus | 7 | 1 | 4 | | J Baker | 2 | 4 | | | | | | | | | |
| | J Statham | 2 | 3 | | 6 | R Sweeting | 6 | 6 | | | | | | | | | |
| 6 | R Sweeting | 6 | 6 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | A Kuznetsov | 6 | 6 | | | | | | | | | | | | | | | |
| | G Jones | 4 | 3 | | 8 | A Kuznetsov | 6 | 3 | 3 | | | | | | | | | |
| Q | M Reid | 7 | 6 | | Q | M Reid | 4 | 6 | 6 | | | | | | | | | |
| LL | N Monroe | 6$^3$ | 1 | | | | | | | Q | M Reid | 2 | 2 | | | | | |
| | J Ward | 7 | 1 | 4 | | | | | | 4 | B Dabul | 6 | 6 | | | | | |
| | V Estrella | 6$^1$ | 6 | 6 | | V Estrella | 4 | 2 | | | | | | | | | | |
| | L Cook | 2 | 1 | | 4 | B Dabul | 6 | 6 | | | | | | | | | | |
| 4 | B Dabul | 6 | 6 | | | | | | | | | | | | 4 | B Dabul | 6 | 6 |
| 7 | D Young | 4 | 4 | | | | | | | | | | | | Q | D Garza | 1 | 2 |
| SE | J Sirianni | 6 | 6 | | SE | J Sirianni | 3 | 6$^5$ | | | | | | | | | | |
| Q | D Garza | 6 | 4 | 6 | Q | D Garza | 6 | 7 | | | | | | | | | | |
| PR | A Satschko | 4 | 6 | 1 | | | | | | Q | D Garza | 6 | 4 | 7 | | | | |
| Q | Dayne Kelly | 2 | 6 | 6 | | | | | | 2 | J Levine | 4 | 6 | 5 | | | | |
| Q | M Ryderstedt | 6 | 3 | 4 | Q | D Kelly | 1 | 1 | | | | | | | | | | |
| | C Gârd | 3 | 2 | | 2 | J Levine | 6 | 6 | | | | | | | | | | |
| 2 | J Levine | 6 | 6 | | | | | | | | | | | | | | | |