OpenLLM-France/wikimedia huggingface dataset:
# Ernie Smith (American football coach)

Ernie E. Smith was an American football coach. He was the eighth head football coach at Adams State College—now known as Adams State University—in Alamosa, Colorado, serving for two seasons, from 1957 to 1958, and compiled a record of 1–17–1.
Smith played college football at Colorado State College of Education—now known as University of Northern Colorado, where he was All-Rocky Mountain Conference selection at tackle. From 1951 to 1955, he coached football at Holly High School in Holly, Colorado, where he led his teams to a record of 55–5 and three state championships in five seasons. Smith joined the coaching staff at Adams State in 1956 as line coach under head football coach Michael Stimack.
Smith resigned from his post at Adams State after the 1958 season. In 1967, he was hired to coach the line at Southern Colorado State College—now known as Colorado State University Pueblo—under head football coach Joe Prater.

## Head coaching record
### College

| Year | Team | Overall | Conference | Standing |
| Adams State Indians (Rocky Mountain Conference) (1957–1958) ||||||
| 1957 | Adams State | 0–9–1 | 0–4–1 | 6th |
| 1958 | Adams State | 1–8 | 1–4 | 5th |
| Adams State: | Adams State: | 1–17–1 | 1–8–1 | |
| Total: | Total: | 1–17–1 | | |
# 1964 State College of Iowa Panthers football team

The 1964 State College of Iowa Panthers football team represented the State College of Iowa in the 1964 NCAA College Division football season. The Panthers offense scored 269 points while the defense allowed 100 points.
Junior halfback Randy Schultz received first-team honors on the 1964 Little All-America college football team after tallying more rushing yards than all of the Panthers' opponents.

## Schedule

| Date | Opponent | Site | Result | Attendance |
| September 12 | Northern Michigan* | O. R. Latham StadiumCedar Falls, IA | W 14–7 | |
| September 19 | at Mankato State* | Blakeslee StadiumMankato, MN | W 36–0 | |
| September 23 | North Dakota State | O. R. Latham StadiumCedar Falls, IA | L 7–14 | 7,000 |
| October 3 | at North Dakota | Memorial StadiumGrand Forks, ND | W 34–0 | 2,500–2,677 |
| October 10 | Drake* | O. R. Latham StadiumCedar Falls, IA | W 41–14 | |
| October 17 | Morningside | O. R. Latham StadiumCedar Falls, IA | W 24–14 | |
| October 24 | Augustana (SD) | O. R. Latham StadiumCedar Falls, IA | W 49–0 | |
| October 31 | at South Dakota State | Coughlin–Alumni StadiumBrookings, SD | W 23–14 | |
| November 7 | at South Dakota | Inman FieldVermillion, SD | W 13–6 | 5,000 |
| November 14 | at Northern Illinois* | Glidden FieldDeKalb, IL | L 9–14 | 7,018–7,019 |
| December 12 | vs. Lamar Tech* | Shotwell StadiumAbilene, TX (Pecan Bowl) | W 19–17 | 7,500 |
| *Non-conference game ||||||

## Team players in the NFL

* Running back Randy Schultz was drafted by the Cleveland Browns in the 5th round (74th overall) of the 1966 NFL draft and was also drafted by the New York Jets in the 20th round (177th overall) of the AFL 1966 Draft.
# Adrian Ellis (composer)

Adrian Ellis is a Canadian film and television composer. He is most noted for his work on the 2022 film Cult Hero, for which he received a Canadian Screen Award nomination for Best Original Score at the 11th Canadian Screen Awards in 2023.
His other credits have included the films The Scarehouse, The Man in the Shadows, The Hoard, The Hyperborean and Mother Father Sister Brother Frank, and the web series Clutch and Out with Dad. He has received several Indie Series Award nominations for his work on Clutch and Out with Dad, and was a Canadian Screen Music Award nominee for Best Original Score for a Short Film in 2022 for Old Mother Tongue.
He has also served as vice-president of the Screen Composers Guild of Canada.
# 1995 Irish Greyhound Derby

The 1995 Irish Greyhound Derby took place during August and September with the final being held at Shelbourne Park in Dublin on 23 September 1995.
The winner Batties Rocket won £50,000 and was trained by Matt O'Donnell, owned and bred by Alicia Swaffield. The race was sponsored by the Kerry Group's dog food product 'Respond'.

## Final result

At Shelbourne, 23 September (over 550 yards):
| Position | Winner | Breeding | Trap | SP | Time | Trainer |
| 1st | Batties Rocket | Batties Whisper - Lady Arrancourt | 6 | 9-2 | 30.19 | Matt O'Donnell |
| 2nd | Batties Spirit | Batties Whisper - Lady Arrancourt | 4 | 7-2 | 30.23 | Matt O'Donnell |
| 3rd | Dew Reward | Phantom Flash - Highway Mystery | 3 | 6-4f | 30.38 | Michael O'Sullivan |
| 4th | Iago | Manx Treasure - Limekiln Pearl | 5 | 33-1 | 30.50 | Matt O'Donnell |
| 5th | Liffey Mills | Phantom Flash - Newhill Abbey | 1 | 5-1 | 30.63 | Ger McKenna |
| 6th | Summerhill Joy | Low Sail - Grange Joy | 2 | 10-1 | 30.64 | Michael Enright |

### Distances

½, 1¾, 1½, 1½, short-head (lengths)

## Competition Report

Trainer Nick Savva sent his 1994 greyhound of the year Westmead Chick and the recent Bar One International winner Westmead Merlin over to Ireland from the UK but in a significant misunderstanding he had failed to bring their stud cards (not needed in UK racing because of the NGRC identity book system). Both had to be withdrawn in an what was a disaster for Savva and the competition. Then Ireland's leading trainer Ger McKenna had greyhounds withdrawn for the same reason but had no misunderstanding to blame.
With the two Westmeads missing it was left to Michael Enright’s 1995 English Greyhound Derby runner-up Summerhill Joy to take the tag as the ante post favourite. Matt O’Donnell and Ger McKenna were well represented as usual as was the exiled John 'Ginger' McGee Sr.
Summerhill Joy duly recorded the fastest qualifying time in 30.33 sec and O’Donnell’s River Lad followed that up by becoming the best in round one with 30.34 but Irish Oaks winner Cool Survivor and Velvet Rocket were both eliminated. Another O’Donnell star Batties Spirit set the standard in round two with a 30.24.
Michael O'Donovan’s Dew Reward impressed throughout the competition and in the quarter-finals Matt O'Donnell trained four runners through to the semi-finals. The first of those four put his name in the record books producing a track record of 29.97 and breaking the 30 second barrier for 550 yards. The previous mark (29.99) by Trade Official set two months previous had been bettered. Batties Rocket and Iago earned O'Donnell two more finalists. The second semi-final resulted in Batties Spirit defeating Summerhill Joy and Liffey Mills.
Dew Reward was a hot favourite for the final but made a mess of the start, this left Batties Rocket to take up the early lead before his sister Batties Spirit challenged. At the first bend Dew Reward was making progress but as Batties Spirit was forced to check she bumped into Dew Reward leaving Batties Rocket with a clear lead. He held on despite a renewed attempt from his sister who only lost out by three quarters of a length.
# Alistair Sutcliffe

Alistair G. Sutcliffe (born 1951) is a British scientist and Emeritus Professor of Systems Engineering at the School of Informatics of the University of Manchester, specialized in requirements engineering, user interface design and safety-critical systems.

## Life and work

Sutcliffe received his MA in Natural Sciences from the University of Cambridge, and his PhD in Ethology from the University of Wales.
Before he started his academic career in the City and Manchester Universities, he had worked in the civil service, the finance industry and the IT industry. He retired from the University of Manchester in October 2011.
His research spans "software engineering, human computer interaction, cognitive and social science, with recent interests in scenario based design, methods for requirements engineering, analysis and modelling complex socio technical systems, visualisation and creative design."

## Publications

* — (1988). Jackson system development.
* — (1995) [1988]. Human-computer interface design (2nd ed.).
* — (1994). Business information systems.
* — (2002). User-Centred Requirements Engineering. Springer.
* — (2002). The Domain Theory: Patterns for knowledge and software reuse. Lawrence Erlbaum Associates.
* — (2003). Designing multisensory user interfaces. Lawrence Erlbaum Associates.
Articles, a selection:
* — (2000). "Requirements analysis for socio-technical system design". Information Systems. 25 (3): 213–233. CiteSeerX 10.1.1.99.5356. doi:10.1016/S0306-4379(00)00016-8.
# Eubela aequatorialis

Eubela aequatorialis is a species of sea snail, a marine gastropod mollusk in the family Raphitomidae.

## Distribution

This marine species occurs off Northeast Sumatra at a depth of 750 m.
# Ashebir Woldegiorgis

Ashebir Woldegiorgis is a member of the Ethiopian parliament and former president of the Ethiopian Football Federation. He is notable as he is the sole independent in the EPDRF-dominated chamber, representing the Bonga constituency. He defeated the head of the Prime Minister's Office and Cabinet Affairs Minister Berhanu Adelo, one of only two EPRDF candidates to be defeated in the 2010 election.
# 1874 in France

Events from the year 1874 in France.

## Incumbents

* President: Patrice de MacMahon, Duke of Magenta
* President of the Council of Ministers: Albert, duc de Broglie (until 22 May), Ernest Courtot de Cissey (starting 22 May)

## Events

* 15 March – France and the Nguyễn dynasty of Vietnam sign the Second Treaty of Saigon, further recognizing the full sovereignty of France over Cochinchina.

## Arts and literature

* 23 January – Camille Saint-Saëns' composition Danse Macabre is premiered.
* 25 April – Louis Leroy reviews the First Impressionist Exhibition, held in Paris, and coins the term with reference to Claude Monet's Impression, Sunrise.

## Births
### January to June

* 21 January – René-Louis Baire, mathematician (died 1932)
* 19 February – Rose Gelbert, golfer (died 1956)
* 22 March – Jean Cau, rower.
* 3 May – François Coty, perfume manufacturer (died 1934)
* 14 May – Polaire (Emilie Marie Bouchaud), singer and actress (died 1939)

### July to December

* 29 July – Auguste Giroux, rugby union player (died 1953)
* 4 September – Jean d'Orléans, duc de Guise, great-grandson of Louis Philippe I, King of the French (died 1940)
* 4 October – Joseph d'Arbaud, poet (died 1950)
* 25 October – Henri Bénard, physicist (died 1939)
* 2 November – Georges Andrique, painter (died 1964)
* 14 November – André-Gaston Prételat, general (died 1969)
* 5 December – Henriette Caillaux, socialite and assassin (died 1943)
* 6 December – Lucien Démanet, gymnast
* 24 December – Yves Le Febvre, writer and politician (died 1959)

## Deaths

* 8 January – Abbé Charles Étienne Brasseur de Bourbourg, writer, historian (born 1814)
* 9 February – Jules Michelet, historian (born 1798)
* 26 August – Julie-Victoire Daubié, journalist (born 1824)
* 12 September – François Guizot, Prime Minister (born 1787)
* 22 December – Louis Aubert-Roche, physician (born 1818)
# Ernie Sings & Glen Picks

Professional ratings :
| Review scores ||
| Source | Rating |
| Allmusic | |
Ernie Sings & Glen Picks is an album by singer Tennessee Ernie Ford and singer/guitarist Glen Campbell, released in 1975.

## Track listing

Side 1:
* "Trouble in Mind" (Richard M. Jones) – 3:02
* "(I'd Be) A Legend in My Time" (Don Gibson) – 2:31
* "Here Comes My Baby Back Again" (Dottie West, Bill West) – 2:52
* "There Goes My Everything" (Dallas Frazier) – 2:55
* "She Called Me Baby" (Harlan Howard) – 3:03
Side 2:
* "Gotta Get My Baby Back" (Floyd Tillman) – 3:40
* "Nobody Wins" (Kris Kristofferson) – 2:52
* "Loving Her Was Easier" (Kris Kristofferson) – 3:02
* "I Really Don't Want to Know" (Music – Don Robertson; Lyrics – Howard Barnes) – 2:48
* "For the Good Times" (Kris Kristofferson) – 3:38

## Personnel

* Ernie Ford – lead vocals
* Glen Campbell – acoustic guitars, harmony vocals
* Chuck Domanico – bass fiddle

## Production

* Producer – Steve Stone
* Engineer – Hugh Davis
* Photography – Rick Rankin
# Adelphocoris rapidus

Adelphocoris rapidus, common names for which are rapid plant bug or superb plant bug, is a species of Hemiptera in the family Miridae, that can be found everywhere in the United States (except for central), and in the Peace–Athabasca Delta, Canada. The species are larger than other members of the family (7–8 millimetres or 0.28–0.31 inch), and are either yellowish-black or orange-black coloured.

## Life cycle
### Egg

Females can lay 35–100 eggs. The greenish-white coloured eggs are laid singly in the stems of plants. The eggs could also be yellow coloured and can turn red by the time of hatching. They are 1.2–1.3 millimetres (0.047–0.051 inches) in length and are 0.3 millimetres (0.012 inches) wide. The eggs shape are cylindrical and are curved, which causes them to be mistaken for the eggs of tarnished plant bugs and pale legume bugs. However, the difference between the species eggs is that rapid plant bug's eggs have a distinct extension or spine. The incubation of the eggs takes 15–20 days of summer.

### Nymph

The nymph have five stages of development and could appear either within 1.8, 2.4, 3.0, 3.8, or 4.8 days, with the total time of 15.4 days. When they appear, they are either brightly red or yellow coloured which depends on the stage in which they currently are. The start out as yellow coloured, transform to reddish-green by next stage, and ending up dark at the very last one. Their abdomen have a wide reddish-brown band that is located near the tip. The antennae have constantly changeable colour light and dark bands,m which usually are of either red or yellow. Both the species abdomen and thorax don't have dark spots that are usually found on the tarnished and pale legume bugs.

### Adult

The adults are 6.8–7.4 millimetres (0.27–0.29 inches) long, with yellowish to red coloured head, legs, and prothorax. Their pronotum is either yellow or yellowish-brown, although they have two large black spots near the hind margin. The hemelytra are brown other than for the lateral edges, which are narrow and yellow coloured. The antennae are black and are ringed with yellowish-white colour. The adult species also could fly, but not high, since the dispersal is not rapid.

## Enemies

Little is known about the predators that hunt this species. In Ontario, they might get eaten by a Peristenus pallipes, a species of parasitoids. The assassin and ambush bugs are common predators too, especially in Alberta.

## Pest

The species feed on alfalfa and sweet clover. They also enjoy feeding on vegetables such as beans, carrots, celery, and potatoes. But they don't stop there, they tend to feed on field crops such as cotton and sugarbeet and also on such weeds as Canada thistle (Cirsium arvense), Rumex and yarrow (Achillea).

## International names

The species are called capside du bouleau in French.
# Dienst

Dienst is a surname. Notable people with the surname include:
* Gottfried Dienst (1919–1998), Swiss football referee
* Robert Dienst (1928–2000), Austrian footballer
# 1995 Comcast U.S. Indoor – Doubles

Jacco Eltingh and Paul Haarhuis were the defending champions, but lost in the final this year.
Jim Grabb and Jonathan Stark won the title, defeating Eltingh and Haarhuis 7–6, 6–7, 6–3 in the final.

## Seeds

* Jacco Eltingh / Paul Haarhuis (final)
* Todd Woodbridge / Mark Woodforde (semifinals)
* Jan Apell / Jonas Björkman (first round)
* Jared Palmer / Richey Reneberg (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Draw

| First round | First round | First round | First round | First round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| 1 | J Eltingh P Haarhuis | 6 | 6 | | | | | | | | | | | | | | | | |
| WC | L Jensen M Jensen | 4 | 2 | | 1 | J Eltingh P Haarhuis | 7 | 6 | | | | | | | | | | | |
| Q | N Broad G Van Emburgh | 6 | 3 | | WC | M Joyce V Spadea | 6 | 3 | | | | | | | | | | | |
| WC | M Joyce V Spadea | 7 | 6 | | | | | | | 1 | J Eltingh P Haarhuis | 7 | 6 | | | | | | |
| 3 | J Apell J Björkman | 4 | 3 | | | | | | | | M Knowles D Nestor | 6 | 4 | | | | | | |
| | M Knowles D Nestor | 6 | 6 | | | M Knowles D Nestor | 6 | 6 | 6 | | | | | | | | | | |
| | T Kronemann D Macpherson | 6 | 6 | 6 | | R Leach S Melville | 7 | 3 | 4 | | | | | | | | | | |
| | R Leach S Melville | 7 | 4 | 7 | | | | | | | | | | | 1 | J Eltingh P Haarhuis | 6 | 7 | 3 |
| | A O'Brien S Stolle | 6 | 3 | | | | | | | | | | | | | J Grabb J Stark | 7 | 6 | 6 |
| | M Bauer D Nargiso | 7 | 6 | | | M Bauer D Nargiso | 4 | 4 | | | | | | | | | | | |
| | J Grabb J Stark | 6 | 6 | | | J Grabb J Stark | 6 | 6 | | | | | | | | | | | |
| 4 | J Palmer R Reneberg | 2 | 4 | | | | | | | | J Grabb J Stark | 6 | 1 | 6 | | | | | |
| | S Lareau B Steven | 4 | 6 | | | | | | | 2 | T Woodbridge M Woodforde | 4 | 6 | 3 | | | | | |
| WC | C van Rensburg D Visser | 6 | 7 | | WC | C van Rensburg D Visser | 4 | 6 | 3 | | | | | | | | | | |
| | J Fitzgerald P Rafter | 3 | 2 | | 2 | T Woodbridge M Woodforde | 6 | 3 | 6 | | | | | | | | | | |
| 2 | T Woodbridge M Woodforde | 6 | 6 | | | | | | | | | | | | | | | | |

## Qualifying
### Qualifiers

* Neil Broad / Greg Van Emburgh

### Qualifying seeds

* Andrew Florent / Kevin Ullyett (qualifying competition)
* Neil Broad / Greg Van Emburgh (qualified)

### Qualifying draw

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 1 | Andrew Florent Kevin Ullyett | 7 | 6 | | | | |
| WC | David DiLucia Jeff Tarango | 6 | 4 | 1 | Andrew Florent Kevin Ullyett | 3 | 6 |
| | Brent Haygarth Byron Talbot | 5 | 5 | 2 | Neil Broad Greg Van Emburgh | 6 | 7 |
| 2 | Neil Broad Greg Van Emburgh | 7 | 7 | | | | |
# Alisma canaliculatum

Alisma canaliculatum, commonly known as channelled water plantain, is a species of plants in the Alismataceae. It is native to Japan, Korea, the Ryukyu Islands, Taiwan, the Kuril Islands, and China (Anhui, Fujian, Guizhou, Henan, Hubei, Hunan, Jiangsu, Jiangxi, Shandong, Sichuan, Zhejiang).
Alisma canaliculatum is a perennial herb with tubers up to 3 cm across. Leaves are lanceolate, up to 50 cm long. Flowers are white, borne in a branching panicle.
# Australasian Mediterranean Sea

The Australasian Mediterranean Sea is a mediterranean sea located in the area between Southeast Asia and Australasia. It connects the Indian and Pacific oceans. It has a maximum depth of 7,440 m and a surface area of 9.08 mil. km².

## Geography

In contrast to the American Mediterranean Sea and Mediterranean Sea, it is not surrounded by continents, only by islands and peninsulas. It includes the following seas:
* South China Sea - 3.5 million km$^2$
* Banda Sea - 695,000 km$^2$
* Arafura Sea - 650,000 km$^2$
* Timor Sea - 610,000 km$^2$
* Java Sea - 320,000 km$^2$
* Gulf of Thailand - 320,000 km$^2$
* Gulf of Carpentaria - 300,000 km$^2$
* Celebes Sea - 280,000 km$^2$
* Sulu Sea - 260,000 km$^2$
* Flores Sea - 240,000 km$^2$
* Molucca Sea - 200,000 km$^2$
* Gulf of Tonkin - 126,250 km$^2$
* Halmahera Sea - 95,000 km$^2$
* Bali Sea - 45,000 km$^2$
* Savu Sea - 35,000 km$^2$
* Joseph Bonaparte Gulf - 26,780 km$^2$
* Seram Sea - 12,000 km$^2$
* Straits of Johor
* Riau Strait
* Karimata Strait
* Lombok Strait
* Luzon Strait
* Makassar Strait
* Ombai Strait
* Strait of Malacca
* Qiongzhou Strait
* Singapore Strait
* Taiwan Strait
* Sunda Strait
* Gaspar Strait
* Wetar Strait
States or territories with a coast on the Australasian Mediterranean Sea are: Australia, Brunei, China, Indonesia, Cambodia, Malaysia, Papua New Guinea, Philippines, Singapore, Taiwan, Thailand, Timor-Leste and Vietnam. It includes the straits of Malacca, Singapore and Luzon, and adjoins the peninsulas of Indochina and Malaysia. The following islands are located within it:
* Bathurst Island, Groote Eylandt, Hainan Dao, Phú Quốc, Ko Chang, Samui archipelago, Nang Yuan, Ko Phangan, Ko Samui, Ko Tao, Tioman, Melville islands, Maluka islands, New Guinea, Paracel Islands, Pratas Island, Philippines, Riau Islands, Sangir Archipelago, Spratly Islands, Greater Sunda Islands (Borneo, Sumatra, Java, Sulawesi), Lesser Sunda Islands (Bali, Flores, Komodo Islands, Lombok, Sumba, Sumbawa, Timor), Taiwan, and Talaud Islands.
# 1874 in Australian literature

This article presents a list of the historical events and publications of Australian literature during 1874.

## Books

* Rolf Boldrewood — My Run Home
* Mary Anne Broome — Sybil's Book
* Marcus Clarke — Chidiock Tichbourne, or The Catholic Conspiracy
* Maud Jean Franc — John's Wife
* Henry Kingsley — Reginald Hetherege

## Short stories

* Marcus Clarke — "Gipsies of the Sea, or The Island of Gold"

## Poetry

* Catherine Martin— The Explorers and Other Poems
* Henry Kendall
** "Rover"
** "Song of the Shingle Splitters"
** "The Voice in the Native Oak"

## Births

A list, ordered by date of birth (and, if the date is either unspecified or repeated, ordered alphabetically by surname) of births in 1874 of Australian literary figures, authors of written works or literature-related individuals follows, including year of death.
* 22 April — James Francis Dwyer, short story writer (died 1952)
* 19 May — Will M. Fleming, politician, novelist and poet (died 1961)
* 31 August — Ambrose Pratt, novelist (died 1944)
* 17 September — Walter Murdoch, academic and essayist (died 1970)
* 17 October — Lionel Lindsay, artist and essayist (died 1961)
* 23 December — Marie Bjelke Petersen, novelist (died 1969)
* 26 December — J. H. M. Abbott, poet and novelist (died 1953)
# Dhandhar River

Dhandhar River is a river near Lalpur, Jamnagar district of Gujarat, India.

## Geology

Dhandhar River is a monsoon river that has water only in the Monsoon season. It has a very less quantity of water in winters while the volume of water increases in the summer season. It flows nearby from Jamnagar's city Lalpur.

## Bridge

Dhandhar River has a bridge in City Lalpur, which is built by Government. It connects Lalpur City to the Temple.

### Tragic accident

Once in past, one GSRTC bus wants to pass from this bridge while raining. But due to water over-flowing, buses go away with water. Most passengers of the people died. Help comes to save them, but all goes in vain. All passengers died due to drowning.

## Use of water

Each drop of water should be used, where there is a shortage of water. Here water shortage happened in every year. In this river, there is no water in summer. But in winter and monsoon, there is some water. And in monsoon, sometimes, there is over-flow of water. So people around the river drain water from the river and use it for agriculture use and personal use also.
# Efax (software)

efax is an integrated fax program for Unix-like computer systems, produced by Casas Communications Engineering since 1993.
The software allows users to send and receive faxes using a computer, fax modem, and telephone line. It is command-line based, but there are several graphical user interfaces available.
efax is open-source and free software, licensed under the GPL. It is included in several major Linux distributions, including Debian, Red Hat, Mandriva, and others. There is also a BSD version, and it forms part of the Apple Mac OS X Darwin system.
# Diflomotecan

Diflomotecan (also known as BN80905) is a chemotherapeutic agent that is a topoisomerase inhibitor (Top1). It varies from other camptothecin based Top1 inhibitors like topotecan in having a 7-membered E-ring. The oxepan-2-one ring in the homocamptothecin analogues is more stable in plasma compared to the 6-membered lactone in camptothecin. Diflomotecan was the first homocamptothecin to enter clinical trials and is currently in phase I for treating patients with sensitive small cell lung cancer (SCLC).