# 2022 Orlando Open – Singles

Christopher Eubanks was the defending champion but lost in the quarterfinals to Wu Yibing.
Wu won the title after Jason Kubler retired in the middle of the third set with the score 6–7$^{(5–7)}$, 6–4, 3–1 in favor of Wu.

## Seeds

* J. J. Wolf (semifinals)
* Emilio Gómez (semifinals)
* Christopher Eubanks (quarterfinals)
* Jason Kubler (final, retired)
* Michael Mmoh (first round)
* Altuğ Çelikbilek (first round)
* Bjorn Fratangelo (first round)
* Rinky Hijikata (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| 1 | J. J. Wolf | 1 | 3 | | | | | |
| 4 | Jason Kubler | 6 | 6 | | | | | |
| 4 | Jason Kubler | 6 | 6 | 4 | Jason Kubler | 7$^7$ | 4 | 1$^r$ |
| | | | | PR | Wu Yibing | 6$^5$ | 6 | 3 |
| PR | Wu Yibing | 6 | 6 | PR | Wu Yibing | 6$^5$ | 6 | 3 |
| 2 | Emilio Gómez | 4 | 1 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | J. J. Wolf | 6 | 6 | | | | | | | | | | | | | | | |
| Q | M Damm | 3 | 1 | | 1 | J. J. Wolf | 7 | 3 | 6 | | | | | | | | | |
| WC | B Holt | 6 | 6 | | WC | B Holt | 5 | 6 | 3 | | | | | | | | | |
| | E Kırkın | 2 | 3 | | | | | | | 1 | J. J. Wolf | 4 | 6 | 6 | | | | |
| | Y Uchiyama | 1 | 6 | 6 | | | | | | | T-l Wu | 6 | 3 | 2 | | | | |
| Alt | D Yevseyev | 6 | 3 | 2 | | Y Uchiyama | 6 | 6$^3$ | 1 | | | | | | | | | |
| | T-l Wu | 6 | 7$^7$ | | | T-l Wu | 4 | 7$^7$ | 6 | | | | | | | | | |
| 7 | B Fratangelo | 4 | 6$^5$ | | | | | | | | | | | | 1 | J. J. Wolf | 1 | 3 |
| 4 | J Kubler | 6 | 6 | | | | | | | | | | | | 4 | J Kubler | 6 | 6 |
| Q | K Smith | 2 | 2 | | 4 | J Kubler | 6 | 6 | | | | | | | | | | |
| | S Fanselow | 2 | 6$^5$ | | | N Mejía | 2 | 1 | | | | | | | | | | |
| | N Mejía | 6 | 7$^7$ | | | | | | | 4 | J Kubler | 6 | 3 | 6 | | | | |
| Q | Gilbert Klier Júnior | 6$^5$ | 4 | | | | | | | | U Blanch | 3 | 6 | 1 | | | | |
| | U Blanch | 7$^7$ | 6 | | | U Blanch | 6 | 3 | 6 | | | | | | | | | |
| WC | B Shelton | 3 | 6$^8$ | | 8 | R Hijikata | 0 | 6 | 3 | | | | | | | | | |
| 8 | R Hijikata | 6 | 7$^{10}$ | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | A Çelikbilek | 2 | 2 | | | | | | | | | | | | | | |
| PR | Y Wu | 6 | 6 | | PR | Y Wu | 7$^7$ | 6 | | | | | | | | | |
| | C Harrison | 6 | 6 | | | C Harrison | 6$^2$ | 0 | | | | | | | | | |
| | G Villanueva | 4 | 2 | | | | | | | PR | Y Wu | 6 | 7$^8$ | | | | |
| | K Uchida | 7 | 4 | 3 | | | | | | 3 | C Eubanks | 4 | 6$^6$ | | | | |
| Q | A Andreev | 5 | 6 | 6 | Q | A Andreev | 4 | 7 | 2 | | | | | | | | |
| WC | A Kovacevic | 6$^1$ | 6 | 6$^4$ | 3 | C Eubanks | 6 | 5 | 6 | | | | | | | | |
| 3 | C Eubanks | 7$^7$ | 1 | 7$^7$ | | | | | | | | | | PR | Y Wu | 6 | 6 |
| 5 | M Mmoh | 5 | 3 | | | | | | | | | | | 2 | E Gómez | 4 | 1 |
| Alt | R Quiroz | 7 | 6 | | Alt | R Quiroz | 7 | 7$^8$ | | | | | | | | | |
| Q | M Pervolarakis | 6 | 1 | 4 | Q | M Pecotić | 5 | 6$^6$ | | | | | | | | | |
| Q | M Pecotić | 3 | 6 | 6 | | | | | | Alt | R Quiroz | 2 | 1$^r$ | | | | |
| | H Moriya | 2 | 2 | | | | | | | 2 | E Gómez | 6 | 3 | | | | |
| Alt | M Jaziri | 6 | 6 | | Alt | M Jaziri | 6$^4$ | 2 | | | | | | | | | |
| | Zh Zhang | 4 | 4 | | 2 | E Gómez | 7$^7$ | 6 | | | | | | | | | |
| 2 | E Gómez | 6 | 6 | | | | | | | | | | | | | | |