# Development, Growth & Differentiation

Development Growth & Differentiation is a peer-reviewed scientific journal published by Wiley on behalf of the Japanese Society of Developmental Biologists. It was established in 1950 as Embryologia, obtaining its current title in 1969. The editor-in-chief is Masanori Taira (Chuo University). According to the Journal Citation Reports, the journal has a 2021 impact factor of 3.063.

## Awards

Since 2017, the journal gives three annual awards. The "Editor-in-Chief Prize" is awarded to the most cited article of the last three years, while the "Wiley Prize" has been awarded to the most downloaded article of the previous year. Since 2011, the "Young Investigator Paper Award" have been awarded to a post-doc or graduate student's first author.

## DGD Awards

Editor-in-Chief Prize (Most cited) :
| Year | Author | vol. | page | published | Title | citation |
| 2022 | Kono, N. & Arakawa, K. | 61 | 316- 326 | 2019 | Nanopore sequencing: Review of potential applications in functional genomics | 54 |
| 2021 | Nagata, R. and Igaki, T. | 60 | 522- 530 | 2018 | Cell competition: Emerging mechanisms to eliminate neighbors. | 11 |
| 2020 | Sasaki, Hiroshi | 59 | 12-20 | 2017 | Roles and regulations of Hippo signaling during preimplantation mouse development. | 13 |
| 2019 | Niwa, Yuko S., Niwa, Ryusuke | 58 | 94-105 | 2016 | Transcriptional regulation of insect steroid hormone biosynthesis and its role in controlling timing of molting and metamorphosis. | 12 |
| 2018 | Kazumasa Ohashi | 57 | 275-290 | 2015 | Roles of cofilin in development and its mechanisms of regulation. | 9 |
| 2017 | Noriyuki Kishi, Kenya Sato, Erika Sasaki and Hideyuki Okano | 56 | 53-62 | 2014 | Common marmoset as a new model animal for neuroscience research and genome editing technology | 18 |
| 2016 | Masamitsu Konno, Atsushi Hamabe, Shinichiro Hasegawa, Hisataka Ogawa, Takahito Fukusumi, Shimpei Nishikawa, Katsuya Ohta, Yoshihiro Kano, Miyuki Ozaki, Yuko Noguchi, Daisuke Sakai, Toshihiro Kudoh, Koichi Kawamoto, Hidetoshi Eguchi, Taroh Satoh, Masahiro Tanemura, Hiroaki Nagano, Yuichiro Doki, Masaki Mori and Hideshi Ishii | 55 | 309-318 | 2013 | Adipose-derived mesenchymal stem cells and regenerative medicine. | 32 |
| 2015 | Ramesh S Pillai and Shinichiro Chuma | 54 | 78-92 | 2012 | piRNAs and their involvement in male germline development in mice | 39 |
| 2014 | Erina Kuranaga | 53 | 137-148 | 2011 | Caspase signaling in animal development. | |
| 2013 | Shibata N, Rouhana L, Agata K | 52 | 27-41 | 2010 | Cellular and molecular dissection of pluripotent adult somatic stem cells in planarias | |
| 2012 | Yoshihiko Umesono & Kiyokazu Agata | 51 | 185-195 | 2009 | Evolution and regeneration of the planarian central nervous system. | |
| 2011 | Nagahama, Yoshitaka, Yamashita, Masakane | 50 | 195-219 | 2008 | Regulation of oocyte maturation in fish | 32 |
| 2010 | Agata K, Saito Y, Nakajima E. | 49 | 73-78 | 2007 | Unifying principles of regeneration I: Epimorphosis versus morphallaxis. | |
| 2009 | Agata K, Saito Y, Nakajima E. | 49 | 73-78 | 2007 | Unifying principles of regeneration I: Epimorphosis versus morphallaxis. | |
| 2008 | Zhao, CT; Meng, AM. | 47 | 201-211 | | Sp1-like transcription factors are regulators of embryonic development in vertebrates. | |
| 2007 | Kojima, T. | 46 | 115-129 | 2004 | The mechanism of Drosophila leg development along the proximodistal axis. | |
Wiley Prize (Most downloaded) :
| Year | Author | vol | page | Published | Title | Download# |
| 2022 | Thompson, W. L. & Takebe, T. | 63 | 47- 58 | 2021 | Human liver model systems in a dish | 2766 |
| 2021 | Sakano, H. | 62 | 199- 213 | 2020 | Developmental regulation of olfactory circuit formation in mice. | 1495 |
| 2020 | Kono, Nobuaki, Kono and Kazuharu, Arakawa | 61 | 316-326 | 2019 | Nanopore sequencing: Review of potential applications in functional genomics. | 8171 |
| 2019 | Masaki Kinoshita, Austin Smith | 60 | 44-52 | 2018 | Pluripotency Deconstructed. | 1519 |
| 2018 | Hiroshi Sasaki | 59 | 12-20 | 2017 | Roles and regulations of Hippo signaling during preimplantation mouse development. | 1135 |
| 2017 | Luan Wen and Yun-Bo Shi | 58 | 106-115 | 2016 | Regulation of growth rate and developmental timing by Xenopus thyroid hormone receptor α. | |
| 2016 | Kwok Yeung Tsang, Danny Chan and Kathryn S. E. Cheah | 57 | 179-192 | 2015 | Fate of growth plate hypertrophic chondrocytes: Death or lineage extension? | 733 |
| 2015 | Daisuke Mashiko, Samantha A. M. Young, Masanaga Muto, Hirotaka Kato, Kaori Nozawa, Masaki Ogawa, Taichi Noda, Yeon-Joo Kim, Yuhkoh Satouh, Yoshitaka Fujihara and Masahito Ikawa | 56 | 122-129 | 2014 | Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes. | 3237 |
| 2014 | Ken-ichi Nishijima and Shinji Iijima | 55 | 207-216 | 2013 | Transgenic chickens | |
| 2013 | Ramesh S Pillai and Shinichiro Chuma | 54 | 78-92 | 2012 | piRNAs and their involvement in male germline development in mice. | |
| 2012 | Erina Kuranaga | 53 | 137-148 | 2011 | Caspase signaling in animal development | |
| 2011 | Kazutoshi Takahashi | 52 | 181-193 | 2010 | Direct reprogramming. | 1073 |
| 2010 | Katsube K, Sakamoto K, Tamamura Y, Yamaguchi A. | 51 | 55-67 | 2009 | Role of CCN, a vertebrate specific gene family, in development. | |
| 2009 | Katsube K, Sakamoto K, Tamamura Y, Yamaguchi A. | 51 | 55-67 | 2009 | Role of CCN, a vertebrate specific gene family, in development. | |
| 2008 | Tadahiro Iimura, Olivier Pourquie | 49 | 265-275 | 2007 | Hox genes in time and space during vertebrate body formation. | |
| 2007 | Baharvand H, Jafary H, Massumi M, and Ashtiani SK. | 48 | 323-332 | 2006 | Generation of insulin-secreting cells from human embryonic stem cells. | |
Young Investigator Paper Award :
| Year | Authors・Awardee(bold) | vol | page | published | Title |
| 2022 | Seya, Daiki, Ihara, D., Shirai, M., Kawamura, T., Watanabe, Y. & Nakagawa, O. | 63 | 82- 92 | 2021 | A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis |
| 2022 | Hiraga, Hirokuni, Ishita, Y., Chihara, T. & Okumura, M. | 63 | 488- 500 | 2021 | Efficient visual screening of CRISPR/Cas9 genome editing in the nematode Pristionchus pacificus |
| 2022 | Diaz-Cuadros, Margarete & Pourquie, O. | 63 | 140- 153 | 2021 | In vitro systems: A new window to the segmentation clock |
| 2021 | Inamori, S., Fujii, M., Satake, S., Iida, H., Teramoto, M., Sumi, T., Meno, C., Ishii, Y. and Kondoh, H. | 62 | 243- 259 | 2020 | Modeling early stages of endoderm development in epiblast stem cell aggregates with supply of extracellular matrices. |
| 2021 | Das, P., Salazar, J. L., Li-Kroeger, D., Yamamoto, S., Nakamura, M., Sasamura, T., Inaki, M., Masuda, W., Kitagawa, M., Yamakawa, T., and Matsuno, K. | 62 | 80- 93 | 2020 | Maternal almondex, a neurogenic gene, is required for proper subcellular Notch distribution in early Drosophila embryogenesis. |
| 2021 | Enny, A., Flaherty, K., Mori, S., Turner, N. and Nakamura, T. | 62 | 311- 325 | 2020 | Developmental constraints on fin diversity. |
| 2021 | Onimaru, K. | 62 | 326- 333 | 2020 | The evolutionary origin of developmental enhancers in vertebrates: Insights from non-model species. |
| 2020 | Shiori Yamamoto, Yuji Uchida, Tomomi Ohtani, Erina Nozaki, Chunyang Yin, Yoshihiro Gotoh, Nayuta Yakushiji-Kaminatsui, Tetsuya Higashiyama, Takamasa Suzuki. Tatsuya Takemoto, Yo-ichi Shiraishi,Atsushi Kuroiwa | 61 | 228-251 | 2019 | Hoxa13 regulates expression of common Hox target genes involved in cartilage development to coordinate the expansion of the autopodal anlage. |
| 2020 | Misaki Shirahama, Ichie Steinfeld, Akari Karaiwa, Shigeru Taketani, Astrid Vogel-Höpker, Paul G. Layer, Masasuke Araki | 61 | 252-262 | 2019 | Change in the developmental fate of the chick optic vesicle from the neural retina to the telencephalon. |
| 2020 | Hirono Kina, Takashi Yoshitani, Kazuko Hanyu, Akira Nakamura | 61 | 265-275 | 2019 | Rapid and efficient generation of GFP-knocked-in Drosophila by the CRISPR-Cas9-mediated genome editing. |
| 2019 | Takebayashi-Suzuki, Kimiko, Konishi, H., Miyamoto, T., Nagata, T., Uchida, M., Suzuki, A | 60 | 158-173 | 2018 | Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14. |
| 2019 | Tatsuya Kamimura, Toshiyuki Yamagishi, Yuji Nakajima | 60 | 97-111 | 2018 | Avian coronary endothelium is a mosaic of sinus venosus- and ventricle-derived endothelial cells in a region-specific manner. |
| 2019 | Kazutaka Hosoda, Minako Motoishi, Takuya Kunimoto, Osamu Nishimura, Byulnim Hwang, Sumire Kobayashi, Shigenobu Yazawa, Makoto Mochii, Kiyokazu Agata, Yoshihiko Umesono | 60 | 341-353 | 2018 | Role of MEKK1 in the anterior-posterior patterning during planarian regeneration. |
| 2018 | Hidetaka Katow, Teppei Kanaya, T. Ogawa, R. Egawa and H. Yawo | 59 | 115-128 | 2017 | Regulation of axon arborization pattern in the developing ciliary ganglion: Possible involvement of caspase 3. |
| 2018 | Mayoko Tsuji, M. Morishima, K. Shimizu, S. Morikawa, M. Heglind, S. Enerback, T. Ezaki and J. Tamaoki | 59 | 501-514 | 2017 | Foxc2 influences alveolar epithelial cell differentiation during lung development. |
| 2018 | Kanami Noguchi, Ryota Ishikawa, M. Kawaguchi, K. Miyoshi, T. Kawasaki, T. Hirata, M. Fukui, S. Kuratani, M. Tanaka and Y. Murakami | 59 | 270-285 | 2017 | Expression patterns of Sema3A in developing amniote limbs: With reference to the diversification of peripheral nerve innervation. |
| 2017 | Junming Chen, Xiuli Lian, Juan Du, Songhua Xu, Jianen Wei, Lili Pang, Chanchan Song, Lin He and Shie Wang | 58 | 280-292 | 2016 | Inhibition of phosphorylated Ser473-Akt from translocating into the nucleus contributes to 2-cell arrest and defective zygotic genome activation in mouse preimplantation embryogenesis. |
| 2017 | Yukika Saga, Tomoka Inamura, Nao Shimada and Takefumi Kawata | 58 | 383-399 | 2016 | Regulation of ecmF gene expression and genetic hierarchy among STATa, CudA, and MybC on several prestalk A-specific gene expressions in Dictyostelium. |
| 2017 | Yudai Tokumasu, Atsuo Iida, Zi Wang, Satoshi Ansai, Masato Kinoshita and Atsuko Sehara-Fujisawa. | 58 | 409-421 | 2016 | ADAM12-deficient zebrafish exhibit retardation in body growth at the juvenile stage without developmental defects. |
| 2016 | Eriko Nishitani, Chong Li, Jaehoon Lee, Hiroyo Hotta, Yuta Katayama, Masahiro Yamaguchi and Tsutomu Kinoshita | 57 | 591-600 | 2015 | Pou5f3.2-induced proliferative state of embryonic cells during gastrulation of Xenopus laevis embryo. |
| 2016 | Yasuhiko Tosa, Ayako Hirao, Ikumi Matsubara, Masahumi Kawaguchi, Makiko Fukui, Shigeru Kuratani and Yasunori Murakami | 57 | 40-57 | 2015 | Development of the thalamo-dorsal ventricular ridge tract in the Chinese soft-shelled turtle, Pelodiscus sinensis. |
| 2016 | Caixia Li, Pingping Zhang and Jieruo G. | 57 | 264-237 | 2015 | miR-29a modulates tumor necrosis factor-α-induced osteogenic inhibition by targeting Wnt antagonists. |
| 2015 | Maha Anani, Ikuo Nobuhisa, Mitsujiro Osawa, Atsushi Iwama, Kaho Harada, Kiyoka Saito and Tetsuya Taga | 56 | 469-479 | 2014 | Sox17 as a candidate regulator of myeloid restricted differentiation potential. |
| 2015 | Akiha Nishihara and Chikara Hashimoto | 56 | 214-222 | 2014 | Tail structure is formed when blastocoel roof contacts blastocoel floor in Xenopus laevis. |
| 2015 | Yoshiyuki Matsubara, Atsushi Sakai, Atsushi Kuroiwa and Takayuki Suzuki | 56 | 573-582 | 2014 | Efficient embryonic culture method for, and its early developmental stages. |
| 2014 | Yosuke Horikawa, Haruka Matsumoto, Fumika Yamaguchi, Satomi Ishida and Shigeki Fujiwara | 55 | 776-785 | 2013 | Transcriptional regulation in the early ectodermal lineage of ascidian embryos. |
| 2014 | Shoko Mori, Yuki Moriyama, Kumiko Yoshikawa, Tomoyo Furukawa and Hiroki Kuroda | 55 | 350-358 | 2013 | β-adrenergic signaling promotes posteriorization in Xenopus early development. |
| 2014 | Tong Sun, Bohye Kim and Lou W. Kim | 55 | 207-216 | 2013 | Glycogen Synthase Kinase 3 influences cell motility and chemotaxis by regulating PI3K membrane localization in Dictyostelium. |
| 2013 | Namiko Kamiyama, Ryohei Seki, Hitoshi Yokoyama and Koji Tamura | 54 | 619-632 | 2012 | Heterochronically early decline of Hox expression prior to cartilage formation in the avian hindlimb zeugopod. |
| 2013 | Emiko Yamanishi, Masanori Takahashi, Yumiko Saga and Noriko Osumi | 54 | 785-800 | 2012 | Penetration and differentiation of cephalic neural crest-derived cells in the developing mouse telencephalon. |
| 2013 | Hiroki Ohgami, Masateru Hiyoshi, Md. Golam Mostafa, Hideo Kubo, Shin-Ichi Abe and Kazufumi Takamune | 54 | 660-671 | 2012 | Xtr, a plural tudor domain-containing protein, is involved in the translational regulation of maternal mRNA during oocyte maturation in Xenopus laevis. |
| 2012 | Nariaki Yanagawa, Masahide Sakabe, Hirokazu Sakata, Toshiyuki Yamagishi, Yuji Nakajima | 53 | 366-377 | 2011 | Nodal signal is required for morphogenetic movements of epiblast layer in the pre-streak chick blastoderm. |
| 2012 | Junichi Tasaki, Norito Shibata, Toshihide Sakurai, Kiyokazu Agata, Yoshihiko Umesono | 53 | 389-400 | 2011 | Role of c-Jun N-terminal kinase activation in blastema formation during planarian regeneration. |
| 2012 | Noha Dabour, Tetsuya Bando, Taro Nakamura, Katsuyuki Miyawaki, Taro Mito, Hideyo Ohuchi and Sumihare Noji | 53 | 857-869 | 2011 | Cricket body size is altered by systemic RNAi against insulin signaling components and epidermal growth factor receptor. |
| 2011 | Hideyuki Dekimoto, Toshio Terashima and Yu Katsuyama | 52 | 181-193 | 2010 | Dispersion of the neurons expressing layer specific markers in the reeler brain. |
| 2011 | Nagamoto Kaneko, You Katsuyama, Kazuo Kawamura, and Shigeki Fujiwara | 52 | 457-468 | 2010 | Regenaration of the gut requires retinoic acid in the budding ascidian Polyandrocarpa misakinesis. |
| 2011 | Asaka Uejima, Takanori Amano, Naoki Nomura, Miyuki Noro, Taiji Yasue, Toshihiko Shiroishi, Kunimasa Ohta, Hitoshi Yokoyama1 and Koji Tamura | 52 | 223-234 | 2010 | Anterior shift in gene expression precedes anteriormost digit formation in amniote limbs. |

## Editors-in-chief

The following persons are or have been editor-in-chief:
* Masanori Taira (starting 2020)
* Harukazu Nakamura (2007-2019)
* Sadao Yasugi (2003-2006)
* Makoto Asashima (2000-2002)
* Shimada Hikaru (1997-1999)
* Motonori Hoshi (1995-1996)
* Chiaki Katagiri (1990-1004)
* Mitsuki Yoneda (1987-1989)
* Kiyotaka Yamana (1982-1986)
* Tokindo Okada (1974-1981)
* Masao Sugiyama (1970-1973)
* Tadao Sato (1950-1969)