# 2020–21 Coupe de France preliminary rounds, Nouvelle-Aquitaine

The 2020–21 Coupe de France preliminary rounds, Nouvelle-Aquitaine was the qualifying competition to decide which teams from the leagues of the Nouvelle-Aquitaine region of France took part in the main competition from the seventh round.
A total of eleven teams qualified from the Nouvelle-Aquitaine preliminary rounds. In 2019–20, Pau FC progressed furthest in the main competition, reaching the round of 16 before losing to Paris Saint-Germain 0–2.

## Schedule

A total of 674 teams entered from the region. The draw required a preliminary round involving 132 clubs on 23 August 2020. The remaining 488 teams from the district divisions, Régional 2 and Régional 3 entered at the first round stage on 30 August 2020. The 35 Régional 1 teams entered at the second round stage on 6 September 2020.
The third round draw, which saw the entry of the Championnat National 3 teams, was made on 15 September 2020. The fourth round draw, which saw the entry of the Championnat National 2 teams, was made on 24 September 2020. The fifth round draw was made on 8 October 2020. The sixth round draw was made on 22 October 2020.

### Preliminary round

These matches were played on 22 and 23 August 2020.
Preliminary round results: Nouvelle Aquitaine :
| Tie no | Home team (tier) | Score | Away team (tier) |
| 1. | Football Sud Bastide (10) | 1–6 | AS Pellegrue (12) |
| 2. | Pleumartin-La Roche-Posay FC (12) | 3–1 | Amicale Coussay-les-Bois (11) |
| 3. | AS Civaux (11) | 7–0 | Entente Nanteuil-Verteuil (12) |
| 4. | US Oradour-sur-Glane (11) | 2–0 | FC Chaillac Saillat (12) |
| 5. | ES Montignac 16 (11) | 1–0 | Entente Foot 16 (11) |
| 6. | FC Rouillac (11) | 1–0 | US Pont l'Abbé d'Arnoult (11) |
| 7. | FC Saint-Fraigne (11) | 0–2 | FC de la Soie (11) |
| 8. | AR Cherveux (12) | 0–4 | AS Augé/Azay-le-Brûlé (11) |
| 9. | SEPC Exireuil (11) | 3–2 | AS Sainte-Néomays Romans (12) |
| 10. | AS Saint-Martin-lès-Melle (11) | 2–0 | AS Exoudun (12) |
| 11. | FC Canton de Courçon (11) | 1–3 | US Champdeniers-Pamplie (11) |
| 12. | Croutelle FC (12) | 3–0 | AS Saint-Eloi (11) |
| 13. | ASPTT Bessines (12) | 4–1 | US Chenay-Chey-Sepvret (11) |
| 14. | CS Venise Verte (11) | 3–2 | US Vivonne (11) |
| 15. | US Lambon (12) | 0–8 | Amicale Saint-Martin (12) |
| 16. | SC Bédenac Laruscade (12) | 4–2 | AS Montguyon (11) |
| 17. | FC Valence-en-Pitou/Couhé (13) | 3–0 | ES Aunac (13) |
| 18. | AS Saint-Saviol (12) | 1–2 | US Abzac (11) |
| 19. | AS Blanzay (13) | 1–0 | Espérance Saint-Bonnet-de-Bellac (11) |
| 20. | CAS Bouresse (13) | 0–3 | AS La Jonchère-Saint-Maurice (11) |
| 21. | JS Angoulins (11) | 1–11 | Avenir Autize (11) |
| 22. | US Prahecq (12) | 2–3 | ASS Portugais La Rochelle (11) |
| 23. | Entente Voulmentin-Saint-Aubin-du-Plain-La Coudre (11) | 2–0 | US La Chapelle-Viviers (12) |
| 24. | SC Vouzailles (13) | 0–2 | US Vouillé (11) |
| 25. | AS Saint-Christophe 86 (12) | 1–3 | Bel-Air Rocs OC Poitiers (11) |
| 26. | ASA Couronneries (11) | 1–1 (3–4 p) | AS Saint-Léger Montbrillais (11) |
| 27. | ASC Portugais Parthenay et de Gâtine (11) | 2–4 | US Brion 79 (11) |
| 28. | ASC Poitiers-Biard (11) | 2–1 | ES Saint-Amand-sur-Sèvre (11) |
| 29. | SC L'Absie-Largeasse/Moutiers-sous-Chantmerle (11) | 3–0 | CDJ Pompaire (12) |
| 30. | US Vergentonnaise (12) | 2–1 | FC Jardres (12) |
| 31. | ES Vouneuil-sous-Biard (12) | 4–1 | AS Coulonges-Thouarsais (11) |
| 32. | FC ASM (11) | 2–3 | US Leigné-sur-Usseau (11) |
| 33. | ES Boismé Clessé (12) | 1–1 (5–4 p) | FC Chiché (11) |
| 34. | AS Colombiers (13) | 4–2 | US Mirebeau (11) |
| 35. | FC Saint-Jean-Missé (11) | 5–1 | US Cissé (12) |
| 36. | SC Champagné-Saint-Hilaire (12) | 0–3 | Diables Bleus Bersac (11) |
| 37. | US Availles-Limouzine (14) | 1–8 | Fontafie FC (11) |
| 38. | CS Chatain (12) | 1–0 | Entente Saint-Maurice-Gençay (14) |
| 39. | CMS Haut-Médoc (11) | 2–3 | Alerte Cussacaise FC (11) |
| 40. | Saint-Aulaye Sports (11) | 1–7 | AS Pugnac (10) |
| 41. | JS Grand Champagne (11) | 1–3 | US Coutras (11) |
| 42. | AS Sauveterrienne (11) | 2–0 | AS Beautiran FC (12) |
| 43. | AS Morizes (11) | 0–6 | ES Mazères-Roaillan (11) |
| 44. | Union Saint-Jean (11) | 0–1 | SC Monségur (11) |
| 45. | US Allemans-du-Dropt (11) | 1–1 (9–8 p) | SC Saint-Morillon (11) |
| 46. | US Farguais (11) | 1–3 | SJ Yvrac (11) |
| 47. | SC Astaffortais (11) | 1–1 (11–10 p) | SJ Bergerac (11) |
| 48. | RC Dax (11) | 1–1 (2–4 p) | SC Taron Sévignacq (11) |
| 49. | Arranoak FC (11) | 1–2 | Kanboko Izarra (11) |
| 50. | Monein FC (11) | 0–1 | Entente Haut Béarn (11) |
| 51. | FC Cubzac-les-Ponts (11) | 4–0 | AS Saint-Germain-Chantérac (11) |
| 52. | AS Coursac (11) | 2–6 | APIS en Aquitaine (12) |
| 53. | FC Pineuilh (11) | 1–2 | US Ludon (11) |
| 54. | Stade Boisseuillais (12) | 2–4 | US Anais (11) |
| 55. | Espoir Haut Vals de Saintonge (11) | 2–3 | ES Fléac (11) |
| 56. | AC Gond-Pontouvre (12) | 0–0 (4–5 p) | CS Trizay-Beurlay (11) |
| 57. | FC Spartak Carsac (12) | 2–1 | AS Villac (12) |
| 58. | CA Brignac (11) | 2–4 | FC Pays Arédien (11) |
| 59. | AS Portugaise Sarlat (11) | 2–1 | APCS Mahorais Brive (11) |
| 60. | SC Séreilhac (11) | 0–1 | USA Terrasson (11) |
| 61. | FC Coly (12) | 8–1 | AS Glandon (13) |
| 62. | AS Marcillac Clergoux (11) | 3–2 | FC Saint-Jal (11) |
| 63. | Parempuyre FC (11) | 3–1 | AS Salles-d'Angles (11) |
| 64. | Saint-Seurin JC (12) | 1–2 | AS Avensan-Moulis-Listrac (11) |
| 65. | AG Vendays-Montalivet (11) | 3–1 | JS Abzac (11) |
| 66. | Ciboure FC (11) | 4–1 | Union Saint-Maurice/Grenade (11) |
* 1 2 3 4 Match won through forfeit.

### First round

These matches were played on 29 and 30 August 2020, with a number postponed until 2, 5 and 6 September 2020.
First round results: Nouvelle Aquitaine :
| Tie no | Home team (tier) | Score | Away team (tier) |
| 1. | FC Parentis (9) | 0–8 | ES Audenge (7) |
| 2. | FC Born (9) | 4–2 | JS Teichoise (9) |
| 3. | AS Facture-Biganos Boïens (8) | 1–0 | Biscarrosse OFC (8) |
| 4. | Stade Ygossais (7) | 3–1 | Les Labourdins d'Ustaritz (8) |
| 5. | JA Biarritz (7) | 0–0 (3–4 p) | FC Belin-Béliet (8) |
| 6. | AS Pontonx (8) | 2–2 (4–5 p) | Croisés Saint-André Bayonne (7) |
| 7. | Hasparren FC (8) | 6–1 | FC Morcenx-Arengosse (8) |
| 8. | Landes Girondines FC (10) | 1–7 | Elan Boucalais (7) |
| 9. | US Armagnac (11) | 3–5 | Papillons de Pontacq (10) |
| 10. | FC Nérac en Albret (9) | 1–5 | US Portugais Pau (7) |
| 11. | FC Casteljaloux (10) | 1–4 | FC des Graves (7) |
| 12. | Fraternelle Landiras (10) | 0–4 | FA Morlaàs Est Béarn (7) |
| 13. | FC Oloronais (9) | 2–3 | FC Roquefort Saint-Justin (9) |
| 14. | Association Saint-Laurent Billère (9) | 2–1 | Langon FC (7) |
| 15. | FC Espagnol Pau (11) | 0–9 | Patronage Bazadais (8) |
| 16. | FC Lacajunte-Tursan (9) | 3–1 | ES Meillon-Assat-Narcastet (8) |
| 17. | FC La Ribère (8) | 2–0 | ES Bournos-Doumy-Garlède (10) |
| 18. | Monflanquin FC (9) | 2–4 | Montesquieu FC (8) |
| 19. | AS Pays de Montaigne et Gurçon (9) | 2–4 | FC Grand Saint-Emilionnais (7) |
| 20. | Colayrac FC (9) | 0–3 | AGJA Caudéran (10) |
| 21. | Prigonrieux FC (7) | 0–2 | FC Côteaux Libournais (8) |
| 22. | US Pays Maixentais (8) | 1–2 | Antran SL (8) |
| 23. | FC Smarves Iteuil (9) | 2–1 | FC Vrines (9) |
| 24. | Gati-Foot (10) | 1–0 | ES Oyré-Dangé (9) |
| 25. | La Ligugéenne Football (7) | 2–0 | ES Saint-Cerbouillé (8) |
| 26. | SL Cenon-sur-Vienne (11) | 2–5 | FC Airvo Saint-Jouin (9) |
| 27. | US Envigne (9) | 2–1 | FC Pays de l'Ouin (8) |
| 28. | US Aigrefeuille (9) | 3–1 | FC Boutonnais (10) |
| 29. | Aviron Boutonnais (9) | 0–1 | US Frontenay-Saint-Symphorien (9) |
| 30. | JS Sireuil (7) | 3–0 | AS Réthaise (7) |
| 31. | UAS Verdille (9) | 2–1 | AS Andilly (10) |
| 32. | ALFC Fontcouverte (10) | 1–2 | Jarnac SF (7) |
| 33. | Saint-Porchaire-Corme Royal FC (10) | 1–1 (2–4 p) | GSF Portugais Angoulême (9) |
| 34. | La Jarrie FC (10) | 3–0 | AS Merpins (7) |
| 35. | US La Crèche (10) | 1–1 (4–5 p) | Capaunis ASPTT FC (8) |
| 36. | FC Portes d'Océan 17 (9) | 2–3 | AS Pays Mellois (8) |
| 37. | FC Périgny (7) | 2–0 | AS Puymoyen (8) |
| 38. | Rochefort FC (7) | 2–2 (3–4 p) | Stade Vouillé (8) |
| 39. | ES Montignac 16 (11) | 4–1 | AS Vérines (11) |
| 40. | AAAM Laleu-La Pallice (8) | 1–2 | Aunis AFC (9) |
| 41. | AS Cabariot (8) | 2–3 | ES Saintes (7) |
| 42. | ES Aunisienne Aytré (10) | 0–7 | Saint-Palais SF (8) |
| 43. | Canton Aunis FC (10) | 3–1 | FC Nord 17 (8) |
| 44. | US Nantiat (9) | 7–0 | CA Égletons (9) |
| 45. | CA Meymac (8) | 1–1 (2–4 p) | Vigenal FC Limoges (8) |
| 46. | Avenir Nord Foot 87 (10) | 1–0 | ES Bénévent-Marsac (9) |
| 47. | Limoges Football (9) | 2–2 (3–0 p) | ES Ussel (9) |
| 48. | EF Aubussonnais (8) | 0–1 | JS Lafarge Limoges (7) |
| 49. | Pleumartin-La Roche-Posay FC (12) | 1–1 (2–4 p) | JS Nieuil l'Espoir (8) |
| 50. | FC Charentais L'Isle-d'Espagnac (10) | 0–4 | Stade Ruffec (7) |
| 51. | USA Montbronn (10) | 0–4 | US Lessac (10) |
| 52. | ACG Foot Sud 86 (10) | 0–2 | FC Charente Limousine (7) |
| 53. | AS Brie (9) | 12–1 | US Le Dorat (10) |
| 54. | Fontafie FC (11) | 1–1 (2–1 p) | OFC Ruelle (8) |
| 55. | AS Civaux (11) | 0–1 | FC Fleuré (9) |
| 56. | FC Confolentais (9) | 2–0 | AS Valdivienne (10) |
| 57. | SC Verrières (9) | 3–2 | US Vicq-sur-Gartempe (8) |
| 58. | US Anais (11) | 3–2 | CS Saint-Angeau (10) |
| 59. | ES Champniers (8) | 1–1 (5–6 p) | FC Rouillé (9) |
| 60. | US Oradour-sur-Glane (11) | 1–1 (1–3 p) | US Leignes-sur-Fontaine (10) |
| 61. | ES Mornac (10) | 2–0 | AS Lussac-les-Églises (11) |
| 62. | FC Canton d'Oradour-sur-Vayres (10) | 2–2 (4–5 p) | US Chasseneuil (10) |
| 63. | AS Saint-Yrieix (9) | 0–0 (4–3 p) | FC Pessac Alouette (7) |
| 64. | Entente Saint-Séverin/Palluaud (10) | 2–0 | FC Cubzac-les-Ponts (11) |
| 65. | CS Saint-Michel-sur-Charente (9) | 1–1 (3–2 p) | SJ Macaudaise (9) |
| 66. | CS Bussac-Forêt (9) | 2–0 | ES Canéjan (10) |
| 67. | AJ Montmoreau (10) | 1–6 | FC Talence (7) |
| 68. | USA Saint-Aigulin (10) | 1–2 | FC Martignas-Illac (8) |
| 69. | SC Mouthiers (9) | 4–1 | ES Eysinaise (9) |
| 70. | CMO Bassens (9) | 3–0 | Gué-de-Sénac FC (10) |
| 71. | FC Arsac-Pian Médoc (8) | 1–1 (3–1 p) | ES Ambares (8) |
| 72. | Périgueux Foot (10) | 4–6 | US Saint-Clementoise (9) |
| 73. | US Pays de Fénelon (10) | 0–1 | ES Nonards (8) |
| 74. | CS Allassac (9) | 0–3 | FC Sarlat-Marcillac (8) |
| 75. | ES Montignacoise (9) | 0–1 | Amicale Saint-Hilaire Venersal (10) |
| 76. | Entente Perpezac Sadroc (9) | 0–3 | SA Sanilhacois (9) |
| 77. | CO Coulouniex-Chamiers (9) | 5–1 | FC Objat (10) |
| 78. | FC Argentat (8) | 2–2 (5–4 p) | Foot Sud 87 (9) |
| 79. | AS Chamberet (8) | 0–3 | AS Eymoutiers (9) |
| 80. | FC Pays Arédien (11) | 1–3 | La Thibérienne (8) |
| 81. | Peyrehorade SF (10) | 4–3 | Baiona FC (10) |
| 82. | CS Lantonnais (8) | 6–0 | FC Barpais (9) |
| 83. | Kanboko Izarra (11) | 0–2 | Labenne OSC (8) |
| 84. | Ciboure FC (11) | 0–7 | AS Tarnos (8) |
| 85. | ES Pyrénéenne (10) | 2–5 | JA Dax (7) |
| 86. | Carresse Salies FC (10) | 0–0 (3–2 p) | AS Lous Marous/FC Saint-Geours (10) |
| 87. | Cazaux Olympique (9) | 1–0 | FREP Saint-Vincent-de-Paul (9) |
| 88. | CA Sallois (9) | 1–1 (4–5 p) | FC Saint-Martin-de-Seignanx (8) |
| 89. | AS des Églantines de Hendaye (9) | 1–1 (3–5 p) | Seignosse-Capbreton-Soustons FC (7) |
| 90. | FC Garazi (10) | 3–5 | Marensin FC (10) |
| 91. | JS Laluque-Rion (9) | 3–2 | SA Mauléonais (8) |
| 92. | Ardanavy FC (11) | 2–0 | Chalosse FC (10) |
| 93. | US Illats (10) | 1–4 | Pardies Olympique (8) |
| 94. | AS Villandraut-Préchac (11) | 3–1 | FA Bourbaki Pau (9) |
| 95. | Sud Gironde FC (10) | 0–2 | AS Mourenx-Bourg (9) |
| 96. | SC Saint-Symphorien (10) | 0–3 | Violette Aturine (8) |
| 97. | CA Castets-en-Dorthe (11) | 1–2 | AS Artix (8) |
| 98. | ES Mazères-Roaillan (11) | 0–0 (5–6 p) | Bleuets Pau (8) |
| 99. | Entente Haut Béarn (11) | 1–1 (4–5 p) | FC Pays Aurossais (8) |
| 100. | FC Artiguelouve-Arbus-Aubertin (10) | 0–0 (2–4 p) | FC Doazit (7) |
| 101. | US Castétis-Gouze (19) | 1–2 | FC Hagetmautien (8) |
| 102. | US Marsan (9) | 0–0 (5–4 p) | Union Jurançonnaise (8) |
| 103. | FC des Enclaves et du Plateau (10) | 1–4 | SC Saint-Pierre-du-Mont (7) |
| 104. | ES Latrille-Saint-Agnet (10) | 0–2 | AL Poey-de-Lescar (7) |
| 105. | SC Arthez Lacq Audejos (8) | 3–1 | SA Saint-Séverin (8) |
| 106. | SC Taron Sévignacq (11) | 0–3 | ES Montoise (8) |
| 107. | VS Caudrot (9) | 2–0 | Saint-Perdon Sports (9) |
| 108. | FC Vallée de l'Ousse (9) | 0–2 | USV Gelosienne (8) |
| 109. | Étoile Béarnaise FC (10) | 1–2 | FC Lons (8) |
| 110. | Avenir Mourenxois (10) | 3–2 | FC Luy du Béarn (8) |
| 111. | ES Nay-Vath-Vielha (9) | 1–2 | AS Mazères-Uzos-Rontignan (8) |
| 112. | FC Côteaux Pécharmant (9) | 0–3 | FC Loubesien (9) |
| 113. | Bouliacaise FC (11) | 2–1 | Pays de l'Eyraud (10) |
| 114. | US Gontaud (9) | 3–5 | US Lamothe-Mongauzy (10) |
| 115. | SC Bastidienne (9) | 1–1 (3–4 p) | AS Marcellus-Cocumont (9) |
| 116. | RC Chambéry (10) | 1–0 | ASSA Pays du Dropt (8) |
| 117. | AS Lusitanos Cenon (9) | 4–0 | Pays de la Force-Ginestet (9) |
| 118. | USJ Saint-Augustin Club Pyrénées Aquitaine (10) | 3–1 | AF Casseneuil-Pailloles-Lédat (8) |
| 119. | CM Floirac (10) | 0–3 | SU Agen (8) |
| 120. | AS Côteaux Dordogne (10) | 3–0 | FC Monbazillac-Sigoules (10) |
| 121. | AS Sauveterrienne (11) | 0–7 | FC Pont-du-Casse-Foulayronnes (9) |
| 122. | USC Léognan (10) | 2–2 (4–5 p) | US La Catte (7) |
| 123. | Sporting Chantecler Bordeaux Nord le Lac (8) | 1–0 | US Virazeil-Puymiclan (9) |
| 124. | CA Carbon-Blanc (10) | 2–5 | FC Vallée du Lot (7) |
| 125. | Targon-Soulignac FC (9) | 2–4 | FC Faux (9) |
| 126. | US Allemans-du-Dropt (11) | 0–2 | CA Béglais (7) |
| 127. | UFC Saint-Colomb-de-Lauzun (9) | 3–0 | FCC Créonnais (10) |
| 128. | SC Astaffortais (11) | – | US Cenon Rive Droite (8) |
| 129. | Agen RC (10) | 1–1 (3–4 p) | Stade Saint-Médardais (7) |
| 130. | SC Monségur (11) | 0–4 | Confluent Football 47 (7) |
| 131. | CS Portugais Villenave-d'Ornon (9) | 4–2 | Montpon-Ménesplet FC (8) |
| 132. | AS Pellegrue (12) | 2–7 | US Bazeillaise (11) |
| 133. | AS Gensac-Montcaret (8) | 2–0 | AS Castillonnès Cahuzac Lalande (8) |
| 134. | RC Bordeaux Métropole (8) | 4–3 | AS Miramont-Lavergne (9) |
| 135. | Mas AC (9) | 0–4 | FC Gradignan (10) |
| 136. | Passage FC (10) | 1–2 | FC Côteaux Bordelais (8) |
| 137. | SC Cadaujac (8) | 1–0 | Entente Boé Bon-Encontre (7) |
| 138. | FC Loudun (10) | 6–1 | ACS Mahorais 79 (10) |
| 139. | ES Boismé Clessé (12) | 0–1 | ASC Poitiers-Biard (11) |
| 140. | Amicale Saint-Martin (12) | 2–7 | Ozon FC (9) |
| 141. | ES La Pallu (11) | 1–2 | US Vasléenne (9) |
| 142. | SEPC Exireuil (11) | 2–2 (3–4 p) | US Thuré-Besse (10) |
| 143. | US Brion 79 (11) | 0–5 | AS Mignaloux-Beauvoir (7) |
| 144. | US Vouillé (11) | 1–3 | RC Parthenay Viennay (7) |
| 145. | US Avanton (10) | 0–2 | ES Aubinrorthais (8) |
| 146. | AS Colombiers (13) | 0–3 | ES Louzy (10) |
| 147. | ES Trois Cités Poitiers (9) | 2–1 | Espérance Terves (8) |
| 148. | SA Mauzé-Rigné (11) | 0–6 | FC Fontaine-le-Comte (8) |
| 149. | US Champdeniers-Pamplie (11) | 1–3 | US Béruges (10) |
| 150. | FC Clazay Bocage (11) | 1–3 | US Jaunay-Clan (10) |
| 151. | US Nord Vienne (10) | 1–2 | SA Moncoutant (7) |
| 152. | FC Montamisé (10) | 0–2 | FC Sud Gâtine (10) |
| 153. | SC L'Absie-Largeasse/Moutiers-sous-Chantmerle (11) | 1–1 (4–3 p) | Chasseneuil-Saint-Georges FC (9) |
| 154. | AS Saint-Léger Montbrillais (11) | 5–3 | CL Noirlieu-Chambroutet Bressuire (11) |
| 155. | Croutelle FC (12) | 0–4 | FC Chanteloup-Courlay-Chapelle (10) |
| 156. | US Saint-Varent Pierregeay (8) | 2–1 | ES Nouaillé (8) |
| 157. | ES Brion-Saint-Secondin (10) | 2–3 | CO Cerizay (8) |
| 158. | ES Beaulieu-Breuil (10) | 2–1 | CEP Poitiers (11) |
| 159. | Bel-Air Rocs OC Poitiers (11) | 0–3 | US Vrère-Saint-Léger-de-Montbrun (10) |
| 160. | US Vergentonnaise (12) | 1–3 | Boivre SC (10) |
| 161. | Avenir Autize (11) | 0–1 | AAS Saint-Julien-l'Ars (10) |
| 162. | Entente Voulmentin-Saint-Aubin-du-Plain-La Coudre (11) | 2–5 | US Mélusine (9) |
| 163. | US Leigné-sur-Usseau (11) | 4–7 | CA Saint-Aubin-le-Cloud (9) |
| 164. | Espérance Availles-en-Châtellerault (10) | 0–6 | US Saint-Sauveur (7) |
| 165. | AS Portugais Châtellerault (8) | 1–1 (1–3 p) | Avenir 79 FC (9) |
| 166. | AS Augé/Azay-le-Brûlé (11) | 1–1 (2–4 p) | ES Saint-Benoit (8) |
| 167. | Union Cernay-Saint-Genest (10) | 0–2 | ES Pays Thénezéen (10) |
| 168. | Buslaurs Thireuil (10) | 1–4 | CS Naintré (7) |
| 169. | ES Château-Larcher (9) | 2–1 | EF Le Tallud (7) |
| 170. | FC Saint-Jean-Missé (11) | 1–3 | ES Beaumont-Saint-Cyr (7) |
| 171. | ES Vouneuil-sous-Biard (12) | 0–1 | ES Ardin (9) |
| 172. | Inter Bocage FC (9) | 2–0 | AS Sèvres-Anxaumont (10) |
| 173. | FC Pays Argentonnais (9) | 0–4 | US Migné-Auxances (7) |
| 174. | ES Fléac (11) | 2–2 (3–4 p) | JS Semussac (10) |
| 175. | SL Châteaubernard (11) | 2–7 | AS Saint-Christophe 17 (10) |
| 176. | FC Haut Val de Sèvre (10) | 1–6 | FC Seudre Ocean (10) |
| 177. | ASPTT Bessines (12) | 2–7 | AS Cozes (7) |
| 178. | ASS Portugais La Rochelle (11) | 2–0 | AL Saint-Brice (10) |
| 179. | ES Clussais (11) | 0–4 | EFC DB2S (8) |
| 180. | FC Essouvert Loulay (10) | 0–5 | UA Niort Saint-Florent (7) |
| 181. | FC de la Soie (11) | 0–3 | ASFC Vindelle (8) |
| 182. | AS Argenteuil Angerien Poursay-Garnaud (10) | 1–2 | ES Celles-Verrines (8) |
| 183. | CS Venise Verte (11) | 0–2 | US Marennaise (8) |
| 184. | AS Aiffres (7) | 1–1 (3–5 p) | Avenir Matha (7) |
| 185. | ES Mougon (11) | 0–2 | US Aulnay (9) |
| 186. | ACS La Rochelle (10) | 1–1 (5–4 p) | CS Leroy Angoulême (7) |
| 187. | AS Saint-Martin-lès-Melle (11) | 0–6 | Oléron FC (8) |
| 188. | US Mauzé-sur-le-Mignon (10) | 1–1 (2–4 p) | Breuil-Magné FC (11) |
| 189. | CS Beauvoir-sur-Niort (10) | 5–0 | ES Tonnacquoise-Lussantaise (10) |
| 190. | ES Saint Just-Luzac (9) | 1–1 (6–7 p) | US Lezay (10) |
| 191. | JS Basseau Angoulême (9) | 0–2 | DR Boucholeurs-Châtelaillon-Yves (10) |
| 192. | FC Marsais (11) | 1–2 | FC Rouillac (11) |
| 193. | ESAB 96 FC (10) | 0–2 | La Rochelle Villeneuve FC (7) |
| 194. | CS Trizay-Beurlay (11) | 0–9 | FC Atlantique (10) |
| 195. | Entente Soubise Port-des-Barques (10) | 0–4 | AS Maritime (8) |
| 196. | FC Saint-Rogatien (10) | 1–2 | US Saujon (9) |
| 197. | AS Reterre Fontanières (10) | 0–5 | AS Ambazac (9) |
| 198. | US Vallière (10) | 2–2 (4–3 p) | AS Saint-Just-le-Martel (10) |
| 199. | ES Evaux-Budelière (10) | 1–0 | FC Saint-Priest-sous-Aixe (10) |
| 200. | US Auzances (9) | 1–1 (0–2 p) | AS Limoges Roussillon (8) |
| 201. | US Felletin (8) | 1–1 (3–4 p) | CA Rilhac-Rancon (7) |
| 202. | US Saint-Vaury (9) | 2–2 (2–4 p) | SA Le Palais-sur-Vienne (7) |
| 203. | RFC Sainte-Feyre (9) | 1–1 (4–5 p) | US Bessines-Morterolles (8) |
| 204. | USC Bourganeuf (9) | 1–2 | USE Couzeix-Chaptelat (7) |
| 205. | CA Peyrat-la-Nonière (9) | 2–3 | Amicale Franco-Portugais Limoges (7) |
| 206. | AC Kurdes Limoges (10) | 1–2 | ES Marchoise (7) |
| 207. | ES Soursac (10) | 2–5 | Limoges Landouge (7) |
| 208. | AS Saint-Louis Val de l'Aurence (10) | 6–0 | AS Bord-Saint-Georges (10) |
| 209. | ES Dun-Naillet (10) | 0–2 | US Saint-Léonard-de-Noblat (8) |
| 210. | Creuse Avenir 2005 (9) | 0–6 | AS Panazol (7) |
| 211. | SC Flayat (11) | 2–7 | US Versillacoise (9) |
| 212. | JS Chambon-sur-Voueize (9) | 0–1 | SC Verneuil-sur-Vienne (8) |
| 213. | Diables Bleus Bersac (11) | 0–5 | CS Boussac (8) |
| 214. | AS La Jonchère-Saint-Maurice (11) | 0–7 | AS Gouzon (7) |
| 215. | US Saint-Fiel (9) | 2–2 (2–4 p) | AS Aixoise (7) |
| 216. | US Beaune-les-Mines (9) | 2–2 (1–2 p) | SC Sardent (9) |
| 217. | AS Saint-Sulpice-le-Guérétois (8) | 0–1 | ES Beaubreuil (7) |
| 218. | US Ma Campagne Angoulême (10) | 3–4 | CA Saint-Savin-Saint-Germain (7) |
| 219. | CS Chatain (12) | 0–4 | FC des 2 Vallées (9) |
| 220. | AS Blanzay (13) | 1–4 | Coqs Rouges Mansle (10) |
| 221. | AS Soyaux (8) | 4–1 | AS Saint-Junien (8) |
| 222. | FC Haute Charente (11) | 0–2 | AS Bel-Air (11) |
| 223. | CA Saint-Victurnien (10) | 1–2 | Avenir Bellac-Berneuil-Saint-Junien-les-Combes (8) |
| 224. | US Abzac (11) | 0–1 | Rochechouart OC (11) |
| 225. | FC Valence-en-Pitou/Couhé (13) | 0–2 | Tardoire FC La Roche/Rivières (8) |
| 226. | FC Usson-Isle (9) | 3–2 | FC Saint-Brice-sur-Vienne (10) |
| 227. | ESE Charentais (10) | 1–1 (3–2 p) | AS Payroux Charroux Mauprévoir (11) |
| 228. | Valence-en-Pitou OC (10) | 1–3 | OC Sommières Saint-Romain (11) |
| 229. | Tour Sportive et Merles Blancs 88 (10) | 0–4 | AS Taillan (8) |
| 230. | AS Saint-Aubin-de-Médoc (10) | 1–2 | Union Pauillac Saint-Laurent (9) |
| 231. | JS Douzillac Saint-Louis (10) | 2–5 | Coqs Rouges Bordeaux (7) |
| 232. | AS Le Haillan (10) | 1–3 | CO La Couronne (8) |
| 233. | FC Cubnezais (11) | 3–1 | US Châteauneuf 16 (10) |
| 234. | AS Neuvic-Saint-Léon (10) | 2–3 | CA Sainte-Hélène (7) |
| 235. | FC Montendre (9) | 0–1 | Union Saint-Bruno (7) |
| 236. | SJ Yvrac (11) | 2–3 | FC Pays de Mareuil (8) |
| 237. | US Coutras (11) | 4–2 | Clérac-Orignolles-Saint-Martin-du-Lary (9) |
| 238. | ES Bruges (10) | 1–0 | ES Linars (9) |
| 239. | AS Avensan-Moulis-Listrac (11) | 2–2 (2–4 p) | AS Villebois Haute Boême (9) |
| 240. | US Ludon (11) | 0–9 | Alliance Foot 3B (8) |
| 241. | Stade Pessacais UC (10) | 4–1 | CA Ribéracois (8) |
| 242. | Nersac FC (10) | 1–2 | AS Pugnac (10) |
| 243. | Entente Grignols Villambard (11) | 0–5 | FC Saint André-de-Cubzac (7) |
| 244. | US Nord Gironde (10) | 3–4 | FC Roullet-Saint-Estèphe (8) |
| 245. | SC Bédenac Laruscade (12) | 4–1 | Saint-Seurin Saint-Estèphe FC (11) |
| 246. | AS Montferrand (10) | 0–2 | FC Sévigné Jonzac-Saint-Germain (8) |
| 247. | US Siant-Denis-de-Pile (10) | 2–1 | FC Médoc Océan (8) |
| 248. | APIS en Aquitaine (12) | 2–1 | FC Médoc Côte d'Argent (7) |
| 249. | ES Fronsadaise (9) | 1–0 | Andernos Sport FC (7) |
| 250. | Alerte Cussacaise FC (11) | 0–1 | Saint-Médard SC (10) |
| 251. | Parempuyre FC (11) | 0–4 | US Bouscataise (7) |
| 252. | FC Lesparre Médoc (10) | 1–3 | RC Laurence (10) |
| 253. | AG Vendays-Montalivet (11) | 2–1 | Stade Blayais (11) |
| 254. | Bordeaux Étudiants CF (10) | 1–2 | FCA Moron (8) |
| 255. | US Marsaneix Manoire (11) | 0–2 | ASPO Brive (8) |
| 256. | USA Terrasson (11) | 1–2 | AS Beynat (8) |
| 257. | Varetz AC (9) | 1–1 (7–6 p) | FC Bassimilhacois (9) |
| 258. | FC Atur (11) | 0–2 | ASV Malemort (9) |
| 259. | US Chancelade/Marsac (9) | 8–0 | Cosnac FC (10) |
| 260. | Entente Troche-Vigeois (10) | 0–1 | Athlético Vernois (10) |
| 261. | ES Ussac (9) | 2–4 | FC Périgord Centre (8) |
| 262. | US Tocane-Saint-Apre (10) | 0–3 | Entente SR3V (9) |
| 263. | Les Aiglons Razacois (10) | 2–11 | US Donzenac (7) |
| 264. | AS Meyssac (11) | 0–7 | US Annesse-et-Beaulieu (10) |
| 265. | Limens JSA (8) | 10–0 | FREP Saint-Germain (9) |
| 266. | AS Collonges Chauffour (11) | 2–0 | FC Spartak Carsac (12) |
| 267. | Olympique Larche Lafeuillade (9) | 4–0 | FC Limeuil (9) |
| 268. | FC Coly (12) | 1–6 | SS Sainte-Féréole (8) |
| 269. | Condat FC (10) | 1–3 | Auvézère Mayne FC (9) |
| 270. | AS Portugaise Sarlat (11) | 2–2 (4–5 p) | US Lanteuil (9) |
| 271. | AS Marcillac Clergoux (11) | 1–5 | AS Châteauneuf-Neuvic (8) |
| 272. | Espoirs La Geneytouse (9) | 2–2 (4–2 p) | FC Cornilois-Fortunadais (9) |
| 273. | Boisseuil FC (10) | 2–3 | Tulle Football Corrèze (7) |
| 274. | Entente des Barrages de la Xaintrie (9) | 1–0 | US Solignac-Le Vigen (10) |
| 275. | Occitane FC (9) | 1–2 | AS Seilhac (10) |
| 276. | AS Nexon (9) | 0–1 | AS Nontron-Saint-Pardoux (7) |
| 277. | US La Roche l'Abeille (9) | 1–1 (3–4 p) | FC Thenon-Limeyrat-Fossemagne (7) |
* 1 2 3 4 Tie reversed from original draw.
* 1 2 3 4 5 Match won by means of forfeit.
* ↑ Match abandoned with the scoreline 1–0. US Cenon Rive Droite penalised. SC Astaffortais qualify.

### Second round

These matches were played on 5, 6, 12 and 13 September 2020, with a number postponed pending outcomes from the previous round.
Second round results: Nouvelle Aquitaine :
| Tie no | Home team (tier) | Score | Away team (tier) |
| 1. | AS Mazères-Uzos-Rontignan (8) | 1–0 | La Brède FC (6) |
| 2. | AS Bel-Air (11) | 0–2 | ES Nonards (8) |
| 3. | ES Celles-Verrines (8) | 1–1 (5–4 p) | FC Chauray (6) |
| 4. | US Marennaise (8) | 1–4 | ES Blanquefort (6) |
| 5. | CA Rilhac-Rancon (7) | 2–0 | SC Verneuil-sur-Vienne (8) |
| 6. | AS Marcellus-Cocumont (9) | 0–1 | Saint-Médard SC (10) |
| 7. | US Envigne (9) | 3–1 | US Saint-Sauveur (7) |
| 8. | JS Nieuil l'Espoir (8) | 0–2 | ES Ardin (9) |
| 9. | CO Cerizay (8) | 2–2 (4–3 p) | US Migné-Auxances (7) |
| 10. | ES Saint-Benoit (8) | 1–3 | Inter Bocage FC (9) |
| 11. | Gati-Foot (10) | 1–1 (1–3 p) | ES Trois Cités Poitiers (9) |
| 12. | FC Airvo Saint-Jouin (9) | 1–4 | ES Buxerolles (6) |
| 13. | FC Loudun (10) | 2–3 | ES Aubinrorthais (8) |
| 14. | Canton Aunis FC (10) | 2–1 | Avenir Matha (7) |
| 15. | DR Boucholeurs-Châtelaillon-Yves (10) | 4–1 | La Jarrie FC (10) |
| 16. | ES Montignac 16 (11) | 0–5 | UA Niort Saint-Florent (7) |
| 17. | US Aulnay (9) | 0–3 | FC Périgny (7) |
| 18. | US Anais (11) | 1–1 (5–3 p) | AS Échiré St Gelais (6) |
| 19. | FC Rouillé (9) | 0–3 | La Rochelle Villeneuve FC (7) |
| 20. | Capaunis ASPTT FC (8) | 2–0 | US Aigrefeuille (9) |
| 21. | FC Rouillac (11) | 0–2 | Oléron FC (8) |
| 22. | US Bessines-Morterolles (8) | 0–0 (5–3 p) | Tardoire FC La Roche/Rivières (8) |
| 23. | ES Mornac (10) | 0–8 | Amicale Franco-Portugais Limoges (7) |
| 24. | Avenir Nord Foot 87 (10) | 0–5 | UES Montmorillon (6) |
| 25. | US Donzenac (7) | 1–1 (3–4 p) | FC Roullet-Saint-Estèphe (8) |
| 26. | FC Sarlat-Marcillac (8) | 7–1 | Entente des Barrages de la Xaintrie (9) |
| 27. | FC Périgord Centre (8) | 4–2 | FC Argentat (8) |
| 28. | Entente Saint-Séverin/Palluaud (10) | 1–3 | AS Saint-Pantaleon (6) |
| 29. | FC Thenon-Limeyrat-Fossemagne (7) | 1–1 (4–5 p) | ASPO Brive (8) |
| 30. | Entente SR3V (9) | 0–4 | CS Saint-Michel-sur-Charente (9) |
| 31. | Auvézère Mayne FC (9) | 4–2 | AS Nontron-Saint-Pardoux (7) |
| 32. | CO Coulouniex-Chamiers (9) | 2–1 | ESA Brive (6) |
| 33. | ES Montoise (8) | 0–2 | Élan Béarnaise Orthez (6) |
| 34. | FC Lacajunte-Tursan (9) | 0–2 | FC Lescar (6) |
| 35. | Patronage Bazadais (8) | 2–0 | Bleuets Pau (8) |
| 36. | FC des Graves (7) | 4–1 | AS Artix (8) |
| 37. | Hasparren FC (8) | 1–2 | St Paul Sport (6) |
| 38. | FC Born (9) | 1–3 | Arin Luzien (6) |
| 39. | Labenne OSC (8) | 2–3 | FC Martignas-Illac (8) |
| 40. | AS Facture-Biganos Boïens (8) | 2–2 (3–2 p) | FC St Médard-en-Jalles (6) |
| 41. | CS Bussac-Forêt (9) | 1–5 | FCE Mérignac Arlac (6) |
| 42. | CA Sainte-Hélène (7) | 4–0 | Saint-Palais SF (8) |
| 43. | FC Sévigné Jonzac-Saint-Germain (8) | 1–0 | AS Lusitanos Cenon (9) |
| 44. | FC Sud Gâtine (10) | 2–3 | CS Naintré (7) |
| 45. | Boivre SC (10) | 4–1 | ES Beaulieu-Breuil (10) |
| 46. | FC Fontaine-le-Comte (8) | 0–0 (8–9 p) | US Saint-Varent Pierregeay (8) |
| 47. | US Leignes-sur-Fontaine (10) | 0–0 (2–4 p) | RC Parthenay Viennay (7) |
| 48. | US Béruges (10) | 1–4 | FC Nueillaubiers (6) |
| 49. | AAS Saint-Julien-l'Ars (10) | 0–5 | SA Moncoutant (7) |
| 50. | SC L'Absie-Largeasse/Moutiers-sous-Chantmerle (11) | 0–3 | AS Mignaloux-Beauvoir (7) |
| 51. | US Vrère-Saint-Léger-de-Montbrun (10) | 1–1 (3–5 p) | US Jaunay-Clan (10) |
| 52. | US Thuré-Besse (10) | 0–11 | Thouars Foot 79 (6) |
| 53. | AS Saint-Léger Montbrillais (11) | 4–1 | US Vasléenne (9) |
| 54. | ES Pays Thénezéen (10) | 0–3 | CA Saint-Savin-Saint-Germain (7) |
| 55. | FC Chanteloup-Courlay-Chapelle (10) | 1–1 (6–7 p) | ES Beaumont-Saint-Cyr (7) |
| 56. | ES Louzy (10) | 1–2 | FC Smarves Iteuil (9) |
| 57. | Avenir 79 FC (9) | 3–3 (4–3 p) | Antran SL (8) |
| 58. | ASC Poitiers-Biard (11) | 0–6 | La Ligugéenne Football (7) |
| 59. | FC Atlantique (10) | 1–5 | Stade Ruffec (7) |
| 60. | ACS La Rochelle (10) | – | Jarnac SF (7) |
| 61. | AS Saint-Christophe 17 (10) | 1–2 | FC Usson-Isle (9) |
| 62. | AS Pays Mellois (8) | 0–3 | ES La Rochelle (6) |
| 63. | Coqs Rouges Mansle (10) | 2–7 | FC Seudre Ocean (10) |
| 64. | JS Semussac (10) | 3–2 | SC Verrières (9) |
| 65. | Breuil-Magné FC (11) | 1–0 | US Mélusine (9) |
| 66. | OC Sommières Saint-Romain (11) | 1–4 | OL Saint-Liguaire Niort (6) |
| 67. | CS Beauvoir-sur-Niort (10) | 2–1 | AS Maritime (8) |
| 68. | ES Château-Larcher (9) | 1–3 | SC Saint-Jean-d'Angély (6) |
| 69. | Stade Vouillé (8) | 1–1 (5–3 p) | US Frontenay-Saint-Symphorien (9) |
| 70. | ASS Portugais La Rochelle (11) | 0–3 | FC Fleuré (9) |
| 71. | EFC DB2S (8) | 2–0 | AS Brie (9) |
| 72. | ASFC Vindelle (8) | 1–1 (2–3 p) | JS Sireuil (7) |
| 73. | ES Evaux-Budelière (10) | 0–2 | Limoges Football (9) |
| 74. | AS Saint-Louis Val de l'Aurence (10) | 3–0 | SA Le Palais-sur-Vienne (7) |
| 75. | US Nantiat (9) | 1–0 | Limoges Landouge (7) |
| 76. | AS Ambazac (9) | 1–0 | US Saint-Léonard-de-Noblat (8) |
| 77. | ESE Charentais (10) | 0–2 | CS Feytiat (6) |
| 78. | US Vallière (10) | 1–4 | Avenir Bellac-Berneuil-Saint-Junien-les-Combes (8) |
| 79. | AS Panazol (7) | 1–0 | FC Charente Limousine (7) |
| 80. | US Versillacoise (9) | 0–8 | JS Lafarge Limoges (7) |
| 81. | AS Eymoutiers (9) | 0–2 | AS Aixoise (7) |
| 82. | AS Limoges Roussillon (8) | 2–1 | FC Confolentais (9) |
| 83. | US Lessac (10) | 2–5 | AS Châteauneuf-Neuvic (8) |
| 84. | Rochechouart OC (11) | 0–3 | ES Guérétoise (6) |
| 85. | GSF Portugais Angoulême (9) | 3–0 | AS Seilhac (10) |
| 86. | ASV Malemort (9) | 1–2 | ES Boulazac (6) |
| 87. | AS Collonges Chauffour (11) | 0–7 | SA Sanilhacois (9) |
| 88. | US Lanteuil (9) | 0–3 | AS Soyaux (8) |
| 89. | US Chancelade/Marsac (9) | 1–0 | Varetz AC (9) |
| 90. | AS Villebois Haute Boême (9) | 2–4 | SS Sainte-Féréole (8) |
| 91. | FC Pays de Mareuil (8) | 2–3 | Olympique Larche Lafeuillade (9) |
| 92. | La Thibérienne (8) | 2–2 (4–3 p) | US Saint-Clementoise (9) |
| 93. | Amicale Saint-Hilaire Venersal (10) | 0–5 | Limens JSA (8) |
| 94. | Athlético Vernois (10) | 0–2 | Tulle Football Corrèze (7) |
| 95. | US Annesse-et-Beaulieu (10) | 1–1 (4–5 p) | AS Beynat (8) |
| 96. | Montesquieu FC (8) | 0–1 | Association Saint-Laurent Billère (9) |
| 97. | FC Pays Aurossais (8) | 0–2 | FC Lons (8) |
| 98. | AL Poey-de-Lescar (7) | 3–1 | FC Doazit (7) |
| 99. | FC Hagetmautien (8) | 1–0 | FA Morlaàs Est Béarn (7) |
| 100. | AS Villandraut-Préchac (11) | 0–3 | Papillons de Pontacq (10) |
| 101. | SC Saint-Pierre-du-Mont (7) | 4–1 | FC La Ribère (8) |
| 102. | USV Gelosienne (8) | 0–3 | SC Cadaujac (8) |
| 103. | AS Mourenx-Bourg (9) | 2–3 | Stade Saint-Médardais (7) |
| 104. | AS Tarnos (8) | 2–6 | SA Mérignac (6) |
| 105. | JS Laluque-Rion (9) | 1–4 | SAG Cestas (6) |
| 106. | Marensin FC (10) | 1–7 | FC Bassin d'Arcachon (6) |
| 107. | FC Gradignan (10) | 0–7 | JA Dax (7) |
| 108. | Coqs Rouges Bordeaux (7) | 0–4 | FC Talence (7) |
| 109. | US Lezay (10) | 1–7 | ES Saintes (7) |
| 110. | AG Vendays-Montalivet (11) | 0–2 | Royan Vaux AFC (6) |
| 111. | SC Bédenac Laruscade (12) | 1–4 | FC Arsac-Pian Médoc (8) |
| 112. | AS Cozes (7) | 3–3 (5–6 p) | FC Estuaire Haute Gironde (6) |
| 113. | AS Taillan (8) | 2–5 | US Saujon (9) |
| 114. | RC Laurence (10) | 1–3 | FC Côteaux Libournais (8) |
| 115. | UFC Saint-Colomb-de-Lauzun (9) | 0–8 | FC des Portes de l'Entre-Deux-Mers (6) |
| 116. | Confluent Football 47 (7) | 1–1 (4–5 p) | RC Bordeaux Métropole (8) |
| 117. | AS Côteaux Dordogne (10) | 1–3 | FC Grand Saint-Emilionnais (7) |
| 118. | CS Portugais Villenave-d'Ornon (9) | 0–5 | US Mussidan-Saint Medard (6) |
| 119. | FC Pont-du-Casse-Foulayronnes (9) | 0–0 (2–4 p) | FC Loubesien (9) |
| 120. | USJ Saint-Augustin Club Pyrénées Aquitaine (10) | 4–4 (3–4 p) | FC Vallée du Lot (7) |
| 121. | FC Faux (9) | 2–1 | RC Chambéry (10) |
| 122. | US Bazeillaise (11) | 0–4 | Jeunesse Villenave (6) |
| 123. | US La Catte (7) | 5–0 | Sporting Chantecler Bordeaux Nord le Lac (8) |
| 124. | FC Cubnezais (11) | 2–0 | APIS en Aquitaine (12) |
| 125. | CA Saint-Aubin-le-Cloud (9) | 0–6 | Ozon FC (9) |
| 126. | FC des 2 Vallées (9) | 0–3 | Vigenal FC Limoges (8) |
| 127. | SC Sardent (9) | 0–3 | USE Couzeix-Chaptelat (7) |
| 128. | AS Gouzon (7) | 2–2 (4–3 p) | JA Isle (6) |
| 129. | SC Astaffortais (11) | 0–3 | FC Roquefort Saint-Justin (9) |
| 130. | Pardies Olympique (8) | 1–1 (4–3 p) | Stade Ygossais (7) |
| 131. | Avenir Mourenxois (10) | 2–4 | US Marsan (9) |
| 132. | Ardanavy FC (11) | 0–6 | Croisés Saint-André Bayonne (7) |
| 133. | Peyrehorade SF (10) | 1–1 (3–4 p) | Hiriburuko Ainhara (6) |
| 134. | FC Belin-Béliet (8) | 3–1 | ES Audenge (7) |
| 135. | AGJA Caudéran (10) | 2–5 | ES Fronsadaise (9) |
| 136. | FC Saint-Martin-de-Seignanx (8) | 1–5 | CS Lantonnais (8) |
| 137. | SC Mouthiers (9) | 2–0 | FC Saint André-de-Cubzac (7) |
| 138. | ES Bruges (10) | 2–1 | Alliance Foot 3B (8) |
| 139. | CO La Couronne (8) | 2–2 (14–13 p) | US Lormont (6) |
| 140. | Union Pauillac Saint-Laurent (9) | 0–3 | US Bouscataise (7) |
| 141. | 'US Coutras (11) | 6–0 | Stade Pessacais UC (10) |
| 142. | US Siant-Denis-de-Pile (10) | 1–1 (4–5 p) | AS Gensac-Montcaret (8) |
| 143. | US Lamothe-Mongauzy (10) | 1–2 | CA Béglais (7) |
| 144. | FC Marmande 47 (6) | – | FC Côteaux Bordelais (8) |
| 145. | CMO Bassens (9) | 0–1 | FC Mascaret (6) |
| 146. | Bouliacaise FC (11) | 1–5 | SU Agen (8) |
| 147. | AS Pugnac (10) | 1–6 | Union Saint-Bruno (7) |
| 148. | Cazaux Olympique (9) | 0–3 | Elan Boucalais (7) |
| 149. | Carresse Salies FC (10) | 0–4 | Seignosse-Capbreton-Soustons FC (7) |
| 150. | Aunis AFC (9) | 6–1 | UAS Verdille (9) |
| 151. | Fontafie FC (11) | 1–2 | Espoirs La Geneytouse (9) |
| 152. | US Chasseneuil (10) | 3–5 | ES Marchoise (7) |
| 153. | CS Boussac (8) | 1–7 | ES Beaubreuil (7) |
| 154. | Violette Aturine (8) | 2–2 (4–5 p) | US Portugais Pau (7) |
| 155. | VS Caudrot (9) | 1–1 (3–0 p) | SC Arthez Lacq Audejos (8) |
| 156. | FCA Moron (8) | 4–1 | AS Saint-Yrieix (9) |
* ↑ Match abandoned after 80 minutes, with the scoreline 1–4, due to fighting and a pitch invasion which required the police to be called. ACS La Rochelle penalised. Jarnac SF qualify.
* 1 2 3 Tie won by means of forfeit.
* 1 2 Tie reversed from original draw.
* ↑ Match abandoned after 75 minutes, with the scoreline 5–0, after FC Côteaux Bordelais were reduced to 7 players (they had started the game with only 8 players due to COVID-19 cases). FC Côteaux Bordelais penalised, FC Marmande 47 qualify.

### Third round

These matches were played on 19 and 20 September 2020.
Third round results: Nouvelle Aquitaine :
| Tie no | Home team (tier) | Score | Away team (tier) |
| 1. | Saint-Médard SC (10) | 1–0 | SU Agen (8) |
| 2. | CA Béglais (7) | 0–4 | FCE Mérignac Arlac (6) |
| 3. | FC Smarves Iteuil (9) | 1–6 | RC Parthenay Viennay (7) |
| 4. | Union Saint-Bruno (7) | 3–1 | SA Mérignac (6) |
| 5. | SC Mouthiers (9) | 0–5 | US Lège Cap Ferret (5) |
| 6. | CS Saint-Michel-sur-Charente (9) | 2–6 | CA Sainte-Hélène (7) |
| 7. | US Saujon (9) | 0–2 | Stade Bordelais (5) |
| 8. | JS Sireuil (7) | 1–1 (5–6 p) | FC Arsac-Pian Médoc (8) |
| 9. | Canton Aunis FC (10) | 0–6 | AS Soyaux (8) |
| 10. | DR Boucholeurs-Châtelaillon-Yves (10) | 1–4 | Stade Vouillé (8) |
| 11. | ES La Rochelle (6) | 4–1 | UA Niort Saint-Florent (7) |
| 12. | CS Naintré (7) | 0–0 (4–5 p) | FC Nueillaubiers (6) |
| 13. | FC Périgny (7) | 2–1 | Jarnac SF (7) |
| 14. | US Anais (11) | 1–4 | Capaunis ASPTT FC (8) |
| 15. | ES Celles-Verrines (8) | 0–2 | SC Saint-Jean-d'Angély (6) |
| 16. | Oléron FC (8) | 0–1 | GSF Portugais Angoulême (9) |
| 17. | La Ligugéenne Football (7) | 3–1 | AS Mignaloux-Beauvoir (7) |
| 18. | US Envigne (9) | 0–6 | CA Neuville (5) |
| 19. | ES Ardin (9) | 3–0 | Ozon FC (9) |
| 20. | Aunis AFC (9) | 3–2 | Stade Ruffec (7) |
| 21. | FC Martignas-Illac (8) | 0–1 | FC Estuaire Haute Gironde (6) |
| 22. | US Bessines-Morterolles (8) | 1–3 | ES Guérétoise (6) |
| 23. | FC Périgord Centre (8) | 1–2 | FC Libourne (5) |
| 24. | FC Lescar (6) | 2–2 (6–5 p) | SC Saint-Pierre-du-Mont (7) |
| 25. | Arin Luzien (6) | 2–2 (4–2 p) | Seignosse-Capbreton-Soustons FC (7) |
| 26. | VS Caudrot (9) | 1–2 | Elan Boucalais (7) |
| 27. | Hiriburuko Ainhara (6) | 1–4 | FC des Graves (7) |
| 28. | Croisés Saint-André Bayonne (7) | 5–2 | Patronage Bazadais (8) |
| 29. | St Paul Sport (6) | 1–3 | Aviron Bayonnais FC (5) |
| 30. | Association Saint-Laurent Billère (9) | 3–2 | FC Roquefort Saint-Justin (9) |
| 31. | Jeunesse Villenave (6) | 5–1 | FC Vallée du Lot (7) |
| 32. | CO Coulouniex-Chamiers (9) | 1–2 | FC Mascaret (6) |
| 33. | ES Marchoise (7) | 2–3 | CA Rilhac-Rancon (7) |
| 34. | Avenir Bellac-Berneuil-Saint-Junien-les-Combes (8) | 0–7 | US Chauvigny (5) |
| 35. | UES Montmorillon (6) | 2–1 | Amicale Franco-Portugais Limoges (7) |
| 36. | AS Aixoise (7) | 1–0 | ES Nonards (8) |
| 37. | Limoges Football (9) | 2–0 | Auvézère Mayne FC (9) |
| 38. | Tulle Football Corrèze (7) | 5–0 | Vigenal FC Limoges (8) |
| 39. | AS Châteauneuf-Neuvic (8) | 1–1 (3–4 p) | La Thibérienne (8) |
| 40. | JS Lafarge Limoges (7) | 1–1 (5–4 p) | AS Beynat (8) |
| 41. | FC Roullet-Saint-Estèphe (8) | 1–3 | US Bouscataise (7) |
| 42. | ES Blanquefort (6) | 2–3 | ES Saintes (7) |
| 43. | FC Talence (7) | 3–0 | FC Sévigné Jonzac-Saint-Germain (8) |
| 44. | FC Seudre Ocean (10) | 2–2 (2–4 p) | FCA Moron (8) |
| 45. | JS Semussac (10) | 0–1 | RC Bordeaux Métropole (8) |
| 46. | ES Bruges (10) | 2–1 | CO La Couronne (8) |
| 47. | FC Fleuré (9) | 0–3 | USE Couzeix-Chaptelat (7) |
| 48. | FC Usson-Isle (9) | 4–3 | US Nantiat (9) |
| 49. | ES Beaubreuil (7) | 0–1 | AS Gouzon (7) |
| 50. | AS Ambazac (9) | 1–4 | CA Saint-Savin-Saint-Germain (7) |
| 51. | FC Cubnezais (11) | 1–3 | Royan Vaux AFC (6) |
| 52. | EFC DB2S (8) | 0–3 | OL Saint-Liguaire Niort (6) |
| 53. | Inter Bocage FC (9) | 1–3 | ES Buxerolles (6) |
| 54. | AS Saint-Léger Montbrillais (11) | 0–5 | SA Moncoutant (7) |
| 55. | Boivre SC (10) | 0–8 | Thouars Foot 79 (6) |
| 56. | ES Trois Cités Poitiers (9) | 4–2 | CO Cerizay (8) |
| 57. | Avenir 79 FC (9) | 0–1 | SO Châtellerault (5) |
| 58. | US Jaunay-Clan (10) | 1–0 | ES Aubinrorthais (8) |
| 59. | ES Beaumont-Saint-Cyr (7) | 0–2 | FC Bressuire (5) |
| 60. | CS Beauvoir-sur-Niort (10) | 0–1 | La Rochelle Villeneuve FC (7) |
| 61. | Breuil-Magné FC (11) | 0–3 | UA Cognac (5) |
| 62. | US Saint-Varent Pierregeay (8) | 0–6 | Stade Poitevin FC (5) |
| 63. | Olympique Larche Lafeuillade (9) | 0–3 | CS Feytiat (6) |
| 64. | AS Panazol (7) | 3–0 | FC Sarlat-Marcillac (8) |
| 65. | CS Lantonnais (8) | 3–1 | Élan Béarnaise Orthez (6) |
| 66. | FC Lons (8) | 0–3 | FC des Portes de l'Entre-Deux-Mers (6) |
| 67. | Pardies Olympique (8) | 0–4 | SAG Cestas (6) |
| 68. | US Portugais Pau (7) | 2–3 | AS Facture-Biganos Boïens (8) |
| 69. | AS Mazères-Uzos-Rontignan (8) | 5–2 | FC Tartas Saint-Yaguen (5) |
| 70. | FC Hagetmautien (8) | 1–2 | FC Marmande 47 (6) |
| 71. | Papillons de Pontacq (10) | 1–7 | JA Dax (7) |
| 72. | Stade Saint-Médardais (7) | 0–2 | Genêts Anglet (5) |
| 73. | US Marsan (9) | 0–1 | AL Poey-de-Lescar (7) |
| 74. | FC Côteaux Libournais (8) | 2–2 (4–5 p) | US Mussidan-Saint Medard (6) |
| 75. | AS Saint-Louis Val de l'Aurence (10) | 2–3 | SS Sainte-Féréole (8) |
| 76. | ASPO Brive (8) | 0–0 (1–3 p) | Espoirs La Geneytouse (9) |
| 77. | AS Limoges Roussillon (8) | 0–2 | AS Saint-Pantaleon (6) |
| 78. | ES Fronsadaise (9) | 1–3 | FC Faux (9) |
| 79. | Limens JSA (8) | 3–1 | FC Loubesien (9) |
| 80. | SC Cadaujac (8) | 1–1 (3–5 p) | ES Boulazac (6) |
| 81. | US Coutras (11) | 2–0 | US Chancelade/Marsac (9) |
| 82. | AS Gensac-Montcaret (8) | 7–0 | US La Catte (7) |
| 83. | SA Sanilhacois (9) | 1–1 (4–3 p) | FC Grand Saint-Emilionnais (7) |
| 84. | FC Belin-Béliet (8) | 1–1 (5–4 p) | FC Bassin d'Arcachon (6) |
* ↑ Tie won by means of forfeit.

### Fourth round

These matches were played on 3, 4 and 6 October, with a number postponed to 7, 10 and 11 October 2020.
Fourth round results: Nouvelle Aquitaine :
| Tie no | Home team (tier) | Score | Away team (tier) |
| 1. | SS Sainte-Féréole (8) | 1–3 | Limoges Football (9) |
| 2. | FC Talence (7) | 0–4 | US Lège Cap Ferret (5) |
| 3. | FC Usson-Isle (9) | 2–2 (9–10 p) | OL Saint-Liguaire Niort (6) |
| 4. | US Chauvigny (5) | 1–4 | Angoulême-Soyaux Charente (4) |
| 5. | Jeunesse Villenave (6) | 1–0 | Croisés Saint-André Bayonne (7) |
| 6. | AS Gouzon (7) | 1–1 (4–5 p) | JS Lafarge Limoges (7) |
| 7. | US Bouscataise (7) | 0–1 | Stade Bordelais (5) |
| 8. | JA Dax (7) | 0–3 | FC Lescar (6) |
| 9. | La Ligugéenne Football (7) | 1–1 (2–4 p) | UES Montmorillon (6) |
| 10. | UA Cognac (5) | 6–1 | FC Mascaret (6) |
| 11. | Royan Vaux AFC (6) | 2–2 (6–5 p) | US Mussidan-Saint Medard (6) |
| 12. | FC Marmande 47 (6) | 0–1 | Stade Montois (4) |
| 13. | AS Facture-Biganos Boïens (8) | 3–2 | SAG Cestas (6) |
| 14. | FC des Graves (7) | 5–0 | AS Mazères-Uzos-Rontignan (8) |
| 15. | Genêts Anglet (5) | 3–0 | Arin Luzien (6) |
| 16. | FC Arsac-Pian Médoc (8) | 1–2 | ES Saintes (7) |
| 17. | FCA Moron (8) | 0–1 | FC des Portes de l'Entre-Deux-Mers (6) |
| 18. | Union Saint-Bruno (7) | 0–2 | CA Sainte-Hélène (7) |
| 19. | FC Périgny (7) | 0–3 | FC Bressuire (5) |
| 20. | CA Saint-Savin-Saint-Germain (7) | 2–6 | SO Châtellerault (5) |
| 21. | ES Ardin (9) | 1–12 | CA Neuville (5) |
| 22. | Aunis AFC (9) | 1–4 | RC Parthenay Viennay (7) |
| 23. | Capaunis ASPTT FC (8) | 0–2 | Stade Poitevin FC (5) |
| 24. | ES Guérétoise (6) | 1–1 (5–6 p) | Trélissac-Antonne Périgord FC (4) |
| 25. | USE Couzeix-Chaptelat (7) | 0–1 | ES Boulazac (6) |
| 26. | CA Rilhac-Rancon (7) | 2–1 | La Thibérienne (8) |
| 27. | AS Aixoise (7) | 2–0 | Tulle Football Corrèze (7) |
| 28. | Saint-Médard SC (10) | 1–0 | US Coutras (11) |
| 29. | FC Faux (9) | 0–4 | FC Libourne (5) |
| 30. | FC Estuaire Haute Gironde (6) | 2–0 | AS Gensac-Montcaret (8) |
| 31. | ES Bruges (10) | 0–1 | Limens JSA (8) |
| 32. | Elan Boucalais (7) | 0–3 | Aviron Bayonnais FC (5) |
| 33. | AL Poey-de-Lescar (7) | 2–2 (5–6 p) | FC Belin-Béliet (8) |
| 34. | CS Lantonnais (8) | 0–0 (2–3 p) | FCE Mérignac Arlac (6) |
| 35. | SA Sanilhacois (9) | 0–9 | Bergerac Périgord FC (4) |
| 36. | AS Soyaux (8) | 0–2 | AS Panazol (7) |
| 37. | AS Saint-Pantaleon (6) | 0–3 | CS Feytiat (6) |
| 38. | Espoirs La Geneytouse (9) | 3–0 | GSF Portugais Angoulême (9) |
| 39. | SA Moncoutant (7) | 2–5 | ES La Rochelle (6) |
| 40. | US Jaunay-Clan (10) | 0–3 | SC Saint-Jean-d'Angély (6) |
| 41. | FC Nueillaubiers (6) | 1–4 | ES Buxerolles (6) |
| 42. | La Rochelle Villeneuve FC (7) | 1–0 | Thouars Foot 79 (6) |
| 43. | Stade Vouillé (8) | 5–1 | ES Trois Cités Poitiers (9) |
| 44. | RC Bordeaux Métropole (8) | 1–1 (7–8 p) | Association Saint-Laurent Billère (9) |
* 1 2 Tie reversed from original draw.
* ↑ Match abandoned at half-time, with the scoreline 0–0, due to floodlight failure. Replayed on 11 October 2020.

### Fifth round

These matches were played on 16, 17 and 18 October.
Fifth round results: Nouvelle Aquitaine :
| Tie no | Home team (tier) | Score | Away team (tier) |
| 1. | Angoulême-Soyaux Charente (4) | 2–3 | Trélissac-Antonne Périgord FC (4) |
| 2. | ES Saintes (7) | 0–3 | CA Neuville (5) |
| 3. | Limoges Football (9) | 0–2 | AS Aixoise (7) |
| 4. | Stade Montois (4) | 1–2 | US Lège Cap Ferret (5) |
| 5. | RC Parthenay Viennay (7) | 1–1 (2–4 p) | Stade Poitevin FC (5) |
| 6. | SC Saint-Jean-d'Angély (6) | 2–1 | La Rochelle Villeneuve FC (7) |
| 7. | JS Lafarge Limoges (7) | 1–1 (2–4 p) | ES La Rochelle (6) |
| 8. | Stade Vouillé (8) | 0–0 (2–3 p) | ES Boulazac (6) |
| 9. | Bergerac Périgord FC (4) | 1–1 (8–9 p) | FC Libourne (5) |
| 10. | ES Buxerolles (6) | 1–1 (5–4 p) | UES Montmorillon (6) |
| 11. | CA Sainte-Hélène (7) | 3–1 | FC Lescar (6) |
| 12. | FC Bressuire (5) | 1–1 (4–2 p) | SO Châtellerault (5) |
| 13. | FC des Portes de l'Entre-Deux-Mers (6) | 1–1 (3–4 p) | FC des Graves (7) |
| 14. | Aviron Bayonnais FC (5) | 5–2 | UA Cognac (5) |
| 15. | AS Facture-Biganos Boïens (8) | 0–1 | Genêts Anglet (5) |
| 16. | Saint-Médard SC (10) | 1–5 | FC Estuaire Haute Gironde (6) |
| 17. | CS Feytiat (6) | 4–2 | CA Rilhac-Rancon (7) |
| 18. | OL Saint-Liguaire Niort (6) | 3–2 | Royan Vaux AFC (6) |
| 19. | Espoirs La Geneytouse (9) | 1–6 | AS Panazol (7) |
| 20. | FC Belin-Béliet (8) | 0–2 | Association Saint-Laurent Billère (9) |
| 21. | Limens JSA (8) | 1–1 (4–2 p) | Jeunesse Villenave (6) |
| 22. | FCE Mérignac Arlac (6) | 1–1 (4–3 p) | Stade Bordelais (5) |
* ↑ Tie reversed from original draw.

### Sixth round

These matches were played on 30 and 31 January 2021.
Sixth round results: Nouvelle Aquitaine :
| Tie no | Home team (tier) | Score | Away team (tier) |
| 1. | FC Libourne (5) | 7–1 | SC Saint-Jean-d'Angély (6) |
| 2. | US Lège Cap Ferret (5) | 3–1 | FC Bressuire (5) |
| 3. | Association Saint-Laurent Billère (9) | 1–1 (3–1 p) | FC Estuaire Haute Gironde (6) |
| 4. | ES La Rochelle (6) | 1–3 | Aviron Bayonnais FC (5) |
| 5. | FC des Graves (7) | 0–0 (2–3 p) | FCE Mérignac Arlac (6) |
| 6. | AS Aixoise (7) | 0–1 | ES Boulazac (6) |
| 7. | Genêts Anglet (5) | 4–0 | CS Feytiat (6) |
| 8. | Limens JSA (8) | 0–5 | Stade Poitevin FC (5) |
| 9. | ES Buxerolles (6) | 1–4 | Trélissac-Antonne Périgord FC (4) |
| 10. | OL Saint-Liguaire Niort (6) | 5–0 | CA Sainte-Hélène (7) |
| 11. | AS Panazol (7) | 1–1 (8–7 p) | CA Neuville (5) |
* ↑ ES Boulazac penalised for fielding a suspended player. AS Aixoise qualify.