OpenLLM-France/wikimedia huggingface dataset:
# Foralumab

Foralumab (TZLS-401), being researched by Tiziana Life Sciences) is a fully human monoclonal antibody that binds to CD3 epsilon of the T cell receptor-CD3 complex. It is currently being studied in a randomized, double-blind placebo-controlled, multicenter dose-ranging study in a nasal formulation in patients with non-active secondary progressive multiple sclerosis (SPMS).

## Clinical research
### Nasal administration
#### Phase 1

Nasal foralumab was studied at the Brigham and Women's Hospital, at the Ann Romney Center. Twenty-seven (9 per group) healthy volunteers received either nasal foralumab (10ug, 50ug, or 250ug daily for 5 days) or they received nasal placebo. Nasal foralumab induced CD8+ Regulatory T cells and reduced CD4+ Suppressor T Cells. Foralumab induced LAP, TIGIT, and KLRG1 immune checkpoint molecules. The treatment was well tolerated by all subjects. The researchers concluded that the Immune effects of nasal foralumab were optimal at the 50ug dose.

#### Phase 2 - Non-active secondary progressive - Multiple sclerosis

Nasal foralumab is currently being studied in the United States in a randomized, double-blind placebo-controlled, multicenter dose-ranging study in a nasal formulation in patients with non-active secondary progressive multiple sclerosis (SPMS). The two primary outcome measures are 1) To determine the safety and tolerability of 50 μg/dose and 100 μg/dose of foralumab nasal compared to placebo and 2) To investigate the effect of foralumab relative to placebo on the change from baseline [18F]PBR06-positron emission tomography (PET) scans for microglial activation, after 12 weeks (3) months of study treatment.

##### Phase 2 - Non-active secondary progressive - Alzheimer's disease

Dr. Howard Weiner announced that nasal foralumab has been cleared by the FDA to be studied in a 6 month phase 2 trial to assess safety, cognition and reduction in microglia PET imaging.

##### Phase 2 - COVID-19

Nasal foralumab was studied in 39 patients with mild to moderate COVID-19. They were randomized into 1) Control {standard of care plus a placebo}, 2) 100 μg/dose of nasal foralumab and 3) 100 μg/dose of nasal foralumab plus dexamethasone. Both nasal foralumab alone and nasal foralumab combined with dexamethasone demonstrated more rapid clearance of lung infiltrates as measured by chest CT compared to the control group.

### Intravenous administration
#### Phase 1 - Crohn's disease

Intravenous foralumab was studied in 39 patients with confirmed active Crohn's disease of at least 6 months duration. The patients were given intravenous infusion daily for 5 days. This limited study did not show efficacy.
# Foramen cecum

Foramen cecum or foramen caecum (from the Latin caecus meaning blind) can refer to:
* Foramen cecum (frontal bone)
* Foramen cecum (tongue)
* Foramen cecum (dental)
# Peter Collins (Victorian politician)

Peter Charles Collins (born 7 October 1941) is an Australian politician. He was a Liberal Party member of the Victorian Legislative Assembly from 1976 to 1982, representing the electorate of Noble Park. He served as secretary to Cabinet from 1981 to 1982.
Collins was born in Bowness-on-Windermere in England, and he attended Tiffin Boys Grammar School in Kingston. He worked as a dry cleaning salesman, labourer, and in a plastics factory prior to migrating to Australia, and was involved in the first wave of the Ban the Bomb marches. He migrated to Australia in 1963, and worked as an encyclopedia salesman and then as a used car salesman from 1965 to 1972. He opened his own car sales business, Peter Collins Motors, in 1972, operating it until his election to parliament. He was a City of Springvale councillor from 1973 to 1979, became chairman of the Westernport Regional Council for Social Development in 1975, and became chairman of the Springvale and Noble Park sewerage authority in 1976.
Collins was elected to the Legislative Assembly at the 1976 state election, winning the new seat of Noble Park. A somewhat outspoken MP, he was a staunch opponent of massage parlors and had a strong interest in consumer affairs issues. He crossed the floor to vote with the National Party and Labor opposition in 1978 over a lack of parliamentary time set aside for discussing social welfare legislation. He was re-elected at the 1979 election. Collins had been floated as a potential minister during his second term, and when Lindsay Thompson ousted Rupert Hamer as Liberal leader and Premier in 1981, Thompson promoted Collins to cabinet secretary. In 1981, he travelled to Italy to locate any victims of the 1980 Irpinia earthquake who may have had family in Australia.
Collins faced a difficult race at the 1982 state election. He only held Noble Park by a 1% margin going into the election, and Labor had recruited Cop Shop actor Terry Norris (who left the successful TV series to enter politics) as their candidate for the seat. Norris soundly defeated Collins as the Cain Labor government came to power, and Collins did not run for office again. He worked as a consultant after leaving politics.
# Forlandsundet

Forlandsundet is an 88 km long sound separating Prins Karls Forland and Spitsbergen. Its northern limits are Fuglehuken to the west and Kvadehuken to the east. Its southern limits are Salpynten to the west and Daudmannsodden to the east.
# Forlandsøyane

Forlandsøyane are three small islands off the southwestern coast of Prins Karls Forland, at the western side of Spitsbergen, Svalbard. The islands are Nordøya, Midtøya and Sørøya. Of these, Midtøya is the largest island. The islands were included in the Forlandsøyane Bird Sanctuary in 1973.
# Gymnastics at the 2019 European Games – Men's parallel bars

The men's artistic gymnastics parallel bars competition at the 2019 European Games was held at the Minsk-Arena on 30 June 2019.

## Qualification

The top six gymnasts with one per country advanced to the final.
| Rank | Gymnast | D Score | E Score | Total | Qual. |
| 1 | David Belyavskiy (RUS) | 6.600 | 8.600 | 15.200 | Q |
| 2 | Vladislav Polyashov (RUS) | 6.500 | 8.633 | 15.133 | |
| 3 | Ferhat Arıcan (TUR) | 6.300 | 8.733 | 15.033 | Q |
| 4 | Brinn Bevan (GBR) | 6.200 | 8.666 | 14.866 | Q |
| 4 | Ahmet Önder (TUR) | 6.200 | 8.666 | 14.866 | |
| 6 | Oleg Verniaiev (UKR) | 6.300 | 8.433 | 14.733 | Q |
| 7 | Marios Georgiou (CYP) | 6.000 | 8.700 | 14.700 | Q |
| 8 | Robert Tvorogal (LTU) | 5.600 | 8.966 | 14.566 | Q |
| 9 | Andrey Likhovitskiy (BLR) | 5.500 | 9.000 | 14.500 | R1 |
| 10 | Nicolò Mozzato (ITA) | 5.500 | 8.600 | 14.100 | R2 |
| 11 | Néstor Abad (ESP) | 5.600 | 8.466 | 14.066 | R3 |

## Final

| Rank | Gymnast | D Score | E Score | Total |
| | Oleg Verniaiev (UKR) | 6.700 | 8.633 | 15.333 |
| | Marios Georgiou (CYP) | 6.000 | 8.900 | 14.900 |
| | Ferhat Arıcan (TUR) | 6.300 | 8.533 | 14.833 |
| 4 | David Belyavskiy (RUS) | 6.600 | 8.133 | 14.733 |
| 5 | Robert Tvorogal (LTU) | 5.600 | 8.600 | 14.200 |
| 6 | Brinn Bevan (GBR) | 6.200 | 7.500 | 13.700 |
# Peter Medak

Péter Medák (born 23 December 1937) is a Hungarian-British film and television director.

## Early life

Born in Budapest, Hungary, he was the son of Elisabeth (née Diamounstein) and Gyula Medak, a textile manufacturer. His family was Jewish. In 1956, he fled his native country for the United Kingdom due to the Hungarian Uprising. There he embarked on a career in the film industry, starting as a trainee and gradually rising to the position of film director.

## Career

Medak was signed to direct television films for MCA Universal Pictures in 1963. In 1967, he signed with Paramount Pictures to make feature films. His first such film was Negatives (1968).
Some of his most notable other works are The Ruling Class (1972), The Changeling (1980), The Krays (1990) and Let Him Have It (1991).
Medak has also directed a number of TV episodes and films, including The Feast of All Saints (a mini-series), Homicide: Life on the Street, The Wire and Carnivàle.

## Personal life

His marriage to his first wife, Katherine LaKermance, with whom he had two children, ended when she died in London in 1972. He had two further children with his second wife, British actress Carolyn Seymour, from whom he was later divorced. Medak's third wife was opera singer Julia Migenes; the marriage lasted from 1988 to 2003.

## Partial filmography

* Negatives (1968)
* A Day in the Death of Joe Egg (1972)
* The Ruling Class (1972)
* The Third Girl From the Left (1973)
* Ghost in the Noonday Sun (1974)
* The Odd Job (1978)
* The Changeling (1980)
* The Babysitter (1980)
* Zorro, The Gay Blade (1981)
* Cry for the Strangers (1982)
* Hart to Hart (1982)
* Faerie Tale Theatre (1984)
** Episode 3.03 "Pinocchio"
** Episode 3.05 "Snow White and the Seven Dwarves"
** Episode 4.02 "The Snow Queen"
** Episode 4.07 "The Emperor's New Clothes"
** Episode 6.03 "The Dancing Princesses"
* The Twilight Zone (1985)
** Episode 1.09 "Dead Woman's Shoes"
* The Men's Club (1986)
* The Metamorphosis, a Study: Nabokov on Kafka (1989)
* The Krays (1990)
* Let Him Have It (1991)
* Romeo Is Bleeding (1993)
* Pontiac Moon (1994)
* The Hunchback (1997)
* Species II (1998)
* David Copperfield (2000)
* The Feast of All Saints (2001) (TV mini-series)
* Masters of Horror (2007)
** Episode "The Washingtonians"
* The Wire (2002)
** Episode 1.03 "The Buys"
* Carnivàle (2003)
** Episode 1.04 "Black Blizzard"
* House (2004)
** Episodes 1.6 "The Socratic Method"
* Sex and Lies in Sin City (2008)
* Breaking Bad (2009)
** Episode 2.06 "Peekaboo"
* Hannibal (2013)
** Episode 1.04 "Œuf"
** Episode 2.03 "Hassun"
* Dating Game Killer (2017)
* The Ghost of Peter Sellers (2018)
# Foreign Missions Society

Foreign Missions Society or Société des Missions-Étrangères may refer to:
Catholic
* Société des Missions Étrangères de Paris (Paris Foreign Missions Society) (MEP), founded in Paris, France in 1660
* Pontifical Institute for Foreign Missions (PIME), independently founded in Milan in 1850 and Rome in 1874, and merged in 1926.
* Saint Joseph's Missionary Society of Mill Hill (MHM), founded in London in 1866.
* Catholic Foreign Mission Society of America (MM), founded in Hawthorne, New York in 1912
* Société des Missions-Étrangères du Québec (Quebec Foreign Missions Society) (PME), founded in Quebec, Canada in 1921
* Saint Patrick's Society for the Foreign Missions (SPS), founded in 1932, headquartered in Ireland
Protestant
# Gymnelia hyaloxantha

Gymnelia hyaloxantha is a moth of the subfamily Arctiinae. It was described by Paul Dognin in 1914. It is found in Colombia.
# Peter Colston (ornithologist)

Peter R. Colston (born 1935) is an English ornithologist.
Colston was Senior Curator at the Natural History Museum until his retirement in 1995. He joined the staff of the museum in 1961, and made collecting trips to Andalucia, Australia and Africa. He became an expert on African birds, publishing description of four new species, including Appert's greenbul. Between 1989 and 1995 he made private trips to China, with Per Alström and Urban Olsson, where they discovered three previously undescribed Phylloscopus warblers.

## Works

* A Field Guide to the Rare Birds of Britain & Europe (with Ian Lewington and Per Alström)
* The Waders of Britain and Europe (with Philip Burton)
* BIRDS of MOUNT NIMBA West Africa LIBERIA (1986) (with Kai Curry-Lindahl)
# Peter Combe's Christmas Album

Peter Combe's Christmas Album is the seventh studio and first Christmas music album by Australian children's musician Peter Combe. It was released in November 1990 and peaked at number 49 on the ARIA Charts, becoming Combe's highest charting album. The album was certified gold in December 1990.

## Track listing

* "Happy Christmas to You"
* "Christmas Eve"
* "Tell Me the Story"
* "Star Shines Bright"
* "Baby Lying in a Manger"
* "Chock a Block (The Inn Keeper's Song)"
* "Rejoice Rejoice"
* "Hang Up Your Stocking"
* "Christmas Is Coming"
* "To You Merry Christmas"
* "Love & Joy"
* "Caesar's Decree Song"
* "Ping"
* "O Little One"
* "Fear Not for I"
* "Christmas Child"
* "Christmas Is Coming"
* All songs composed, arranged and produced by Peter Combe.

## Charts
### Weekly charts

| Chart (1990/91) | Peak position |
| Australian Albums (ARIA) | 49 |

### Year end charts

| Chart (1990) | Rank |
| Australian Albums Chart | 89 |

## Certifications

| Region | Certification | Certified units/sales |
| Australia (ARIA) | Gold | 35,000$^^$ |
| $^^$ Shipments figures based on certification alone. |||

## Release history

| Region | Date | Format | Edition(s) | Label | Catalogue |
| Australia | November 1990 | CD LP | Standard | ABC Records | 846597-1/ 846597-2 |
| Australia | 1999 | CD | Re-release | Rascal Records | RASC06-2 |
# George Stacey (footballer)

George William Stacey (April 1881 – 1972) was an English footballer who played at left back for several English football clubs, including Sheffield Wednesday, Barnsley and Manchester United.
Born in Thorpe Hesley, Rotherham, Stacey began his career with Thorpe Hesley F.C. before signing for Sheffield Wednesday in May 1902. He then joined Barnsley in August 1905, via a short spell with Thornhill United. In April 1907, he was sold to Manchester United for a fee of £200.
Stacey made his Manchester United debut on 12 October 1907, playing at left back in a 6–1 away win over Newcastle United. That season, he made 18 league appearances and scored one goal as United won the First Division title by nine points over Aston Villa - the first major trophy in Manchester United's history. The following year, Stacey played more regularly at right back, playing in 38 matches on the way to the 1909 FA Cup title. In 1910–11, United won the First Division again, albeit only by one point, with Stacey missing only two matches.
As a result of his consistency with Manchester United, Stacey went for a trial with the England national team in 1912. However, he never made an appearance for the team.
Stacey remained with Manchester United until the outbreak of the First World War forced the temporary cancellation of competitive football in England. During the war, Stacey made guest appearances for his hometown club, Rotherham County. He retired from football at the end of the 1918–19 War League season in May 1919.
He died in 1972 at the age of 91, and by this time he was one of Manchester United's last surviving players from their early successes.

## Honours
### Manchester United

* First Division (2): 1907–08, 1910–11
* FA Cup (1): 1908–09
# Peringamala (disambiguation)

Peringamala may refer to:
* Peringammala, a village in Thiruvananthapuram district in the state of north side of Kerala, India. It is 3 km from Venganoor
* Peringamala, a village in Thiruvananthapuram district in the state of Kerala, India. It is the second largest panchayath in Kerala.
# Hesperocyparis sargentii

Hesperocyparis sargentii is a species of conifer in the family Cupressaceae known by the common name Sargent's cypress. It is endemic to California, where it is known from Mendocino County southwards to Santa Barbara County. This taxon is limited to the Coast Range mountains. It grows in forests with other conifers, as well as chaparral and other local mountain habitat, usually in pure stands on serpentine soils. It generally grows 10 to 15 meters (33–50 feet) tall, but it is known to exceed 22 meters (73 feet). On Carson Ridge in Marin County, as well as Hood Mountain in Sonoma County, the species comprises a pygmy forest of trees which do not attain heights greater than 240–360 cm (8–12 feet) due to high mineral concentrations in the serpentine soil.
One notable population occurs in the Cedar Mountain Ridge area of Eastern Alameda County. According to Carl Wolf, who extensively studied the New World Cypress in the 1930s and 1940s, seed from the Cedar Mountain stand of Cupressus sargentii produced the most vigorous seedlings.
Like many of the New World Cupressaceae, Sargent cypress usually reproduces with the aid of wildfire, which cause an opening of the cones and exposure of bare mineral soil for seedling germination, though occasionally seeds will fall and germinate without fire, though such seems to be the exception rather than the rule. It is often the case that many trees in a particular stand will all be the same age, so that a sort of stratification occurs of different colonies all of the same age. Sargent cypress can begin producing cones as early as five or six years of age.

## Taxonomy

Hesperocyparis sargentii was scientifically described by the botanist Willis Linn Jepson in 1909 and given the name Cupressus sargentii. He found the type specimen in the Mayacamas Mountains in northern California. Jepson also identified a variety of the species, var. duttonii, in 1923, but this has not become widely accepted. For almost 100 year the status of the species was not disturbed until in 2006 the first of several proposals to move it to, Callitropsis alongside Callitropsis nootkatensis. Further research lead to two proposals to move it to a new genus for new world species of cypress, Neocupressus and Hesperocyparis. As of 2024 Hesperocyparis sargentii is considered to be the correct classification by Plants of the World Online, World Flora Online, and the USDA Natural Resources Conservation Service PLANTS database.
# Gregory Rose

Gregory or Greg Rose may refer to:
* Gregory G. Rose (born 1955), Australian-born American cryptographer
* Gregory Rose (musician) (born 1948), conductor, composer, arranger and music director
* Perfect (musician) (Greg Rose, born 1980), Jamaican reggae singer
# Winter's Turning

Professional ratings :
| Review scores ||
| Source | Rating |
| Allmusic | |
Winter's Turning is a folk album released in 1986 by Robin Williamson. The album was recorded in Los Angeles.
The album dwelled into the winter holidays and British Isle lore. Williamson does this through instrumental folk and folk ballads. Williamson utilizes the acoustic instruments, including mandolin, hammered dulcimer, and guitar, to the fullest. There is an equal balance of the instrumentals along with vocal performances.

## Track listing

* Drive The Cold Winter Away/Cold and Raw
* Avant De S'En Aller
* Past Time with Good Company/Somerset Wassail
* Greensleeves Morris/Green Groweth the Holly/Eagle's Whistle
* Past 1 O'clock/Great Tom's Cast
* Sheep Under The Snow/Welsh Morris
* Praetorius' Courante/Drive The Cold Winter Away
* Blow Blow Thou Winter Wynd/Vivaldi's Winter Largo/Trip to the Boar/Manage The Miser
* Carolan's Quarrel With The Landlady/Christmas Eve
* Hunting the Wren
* Corelli's Sonato/36 Allegro/Scottish Country Dance
* Polka du Tapis
# Paotai Town

Paotai (Chinese: 炮台镇; pinyin: Pàotái Zhèn) is an unincorporated town (非建制镇) located in Shawan County, Xinjiang Uyghur Autonomous Region, China, it is known for the seat of 121st Regiment headquarters of the 8th Division, Xinjiang Production and Construction Corps. The town is 213 km away from Urumqi in the east, 78 km from Shihezi in the southeast, 110 km from Karamay in the northwest, and 120 km from Kuitun in the southwest. The county-level road of Guxin Line (县道古新线) and the Keyu Expressway (克榆高速公路, Karamay - Yushugou) cross the territory, and connected with contact line, its traffic is very convenient.
The territory of the town is also the area of reclaimed land for the 121st Regiment. It has an area of 704.74 square kilometers with a population of 38,320 (as of 2010 census). The name of Paotai (炮台) was the homophonic Chinese word of "bortai" (博克泰) from the Mongolian language, meaning land with deers (有鹿的地方). The town was named for the first time in 1982 census.

## Infrastructure

With six vertical and six horizontal streets, street layout of Paotai is gridded. From east to west, they are Donghuan Road (东环路), Xiangyang Road (向阳路), Guangming Road (光明路), Guangming South Road (光明南路), Guangming West Road (光明西路), and West Ring Road (西环路), From south to north, Jian'an Road (建安路), Renmin Road (人民路), Limin Road (利民路), Yucai Road (育才路), and North Ring Road (北环路). There are 21 commercial outlets, such as shopping malls, Pharmacy shops, bookstore, a bank, cable TV for residents. Coverage rate of FM radio stations is 100%. There is also Paotai Plaza (炮台广场), East Park (东公园), farmers' market, nursing home, library, a middle school, a primary school, a kindergarten, and a hospital.
# Gmina Szastarka

Gmina Szastarka is a rural gmina (administrative district) in Kraśnik County, Lublin Voivodeship, in eastern Poland. Its seat is the village of Szastarka, which lies approximately 12 kilometres (7 mi) south-east of Kraśnik and 48 km (30 mi) south of the regional capital Lublin.
The gmina covers an area of 73.53 square kilometres (28.4 sq mi), and as of 2006 its total population is 6,236 (5,957 in 2013).

## Villages

Gmina Szastarka contains the villages and settlements of Blinów Drugi, Blinów Pierwszy, Brzozówka, Brzozówka-Kolonia, Cieślanki, Huta Józefów, Majdan-Obleszcze, Polichna, Rzeczyca-Kolonia, Stare Moczydła, Szastarka, Wojciechów and Wojciechów-Kolonia.

## Neighbouring gminas

Gmina Szastarka is bordered by the gminas of Batorz, Kraśnik, Modliborzyce, Potok Wielki, Trzydnik Duży and Zakrzówek.
# 1949 in Pakistan

Events from the year 1949 in Pakistan.

## Incumbents
### Monarch

* King George VI (consort – Queen Elizabeth)

### Federal government

* Governor-General: Khawaja Nazimuddin
* Prime Minister: Liaquat Ali Khan
* Chief Justice: Abdul Rashid (starting 27 June)

### Governors

* Governor of Northwest Frontier: Ambrose Dundas Flux Dundas (until 19 July); Sahibzada Mohammad Khurshid (starting 19 July)
* Governor of West Punjab: Francis Mudie (until 2 August); Abdur Rab Nishtar (starting 2 August)
* Governor of Sindh: Shaikh Din Muhammad (until 19 November); Mian Aminuddin (starting 19 November)

## Events
### January

* 1 January – The UN brokered a cease-fire in Kashmir. It granted Kashmir the right to vote on whether to join Pakistan or India.

### March

* March – Pakistan and India sign the Karachi Agreement
* 7 March – Prime Minister Liaquat Ali Khan presented Objectives Resolution in the assembly.
* 12 March – Objectives Resolution is adopted by Constituent Assembly of Pakistan.

## Births

* 6 March – Shaukat Aziz, former prime minister
* 15 September – Taskeen Manerwal, poet and writer (d. 2022)
* 20 November – Tarek Fatah, journalist (d. 2023 in Canada)
* 25 December – Nawaz Sharif, former prime minister

## Deaths

* 19 June – Syed Zafarul Hasan, Muslim philosopher (b. 1885)
# 1951 Tongan general election

General elections were held in Tonga in 1951

## Electoral system

The Legislative Assembly had seven directly elected members; three representing Tongatapu and nearby islands, two representing Haʻapai and two representing Vavaʻu and nearby islands. A further seven members were elected by the nobility based on the same constituencies, seven ministers (including the governors of Haʻapai and Vavaʻu) and a Speaker chosen by the monarch, Sālote Tupou III.

## Results

Elected members included the commoners Molitoni Finau and Sekonaia Tu'akoi and the noble Semisi Fonua from Tongatapu.