# 2021 LTP Charleston Pro Tennis – Singles

Mayar Sherif was the defending champion but lost to Claire Liu in the second round.
Liu went on to win the title, defeating Madison Brengle in the final, 6–2, 7–6$^{(8–6)}$.

## Seeds

* Madison Brengle (final)
* Caty McNally (first round)
* Mayar Sherif (second round)
* Kristie Ahn (first round)
* Irina Bara (second round)
* Renata Zarazúa (quarterfinals)
* Olga Govortsova (quarterfinals)
* Wang Xinyu (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 1 | Madison Brengle | 7$^8$ | 6 | | | | | |
| | Magdalena Fręch | 6$^6$ | 3 | | | | | |
| | Magdalena Fręch | 6$^6$ | 3 | | 1 | Madison Brengle | 2 | 6$^6$ |
| | | | | | SE | Claire Liu | 6 | 7$^8$ |
| SE | Claire Liu | 4 | 6 | 6 | SE | Claire Liu | 6 | 7$^8$ |
| | Harriet Dart | 6 | 3 | 3 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | M Brengle | 6 | 6 | | | | | | | | | | | | | | |
| | W Osuigwe | 1 | 0 | | 1 | M Brengle | 7 | 6 | | | | | | | | | |
| | F Di Lorenzo | 1 | 2 | | | V Cepede Royg | 5 | 2 | | | | | | | | | |
| | V Cepede Royg | 6 | 6 | | | | | | | 1 | M Brengle | 7 | 7$^7$ | | | | |
| | S Sanders | 6 | 6 | | | | | | | WC | K Volynets | 5 | 6$^3$ | | | | |
| | G Talabă | 0 | 1 | | | S Sanders | 2 | 0 | | | | | | | | | |
| WC | K Volynets | 2 | 6 | 6 | WC | K Volynets | 6 | 6 | | | | | | | | | |
| 8 | Xin Wang | 6 | 3 | 2 | | | | | | | | | | 1 | M Brengle | 7$^8$ | 6 |
| 4 | K Ahn | 4 | 3 | | | | | | | | | | | | M Fręch | 6$^6$ | 3 |
| | M Fręch | 6 | 6 | | | M Fręch | 4 | 6 | 6 | | | | | | | | |
| WC | K Shaffer | 3 | 1 | | Q | V Duval | 6 | 4 | 1 | | | | | | | | |
| Q | V Duval | 6 | 6 | | | | | | | | M Fręch | 6 | 6 | | | | |
| Q | E Hozumi | 4 | 6 | 1 | | | | | | 6 | R Zarazúa | 4 | 1 | | | | |
| | G Min | 6 | 1 | 6 | | G Min | 2 | 1 | | | | | | | | | |
| | H Baptiste | 4 | 1 | | 6 | R Zarazúa | 6 | 6 | | | | | | | | | |
| 6 | R Zarazúa | 6 | 6 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5 | I Bara | 4 | 6 | 6 | | | | | | | | | | | | | | | |
| | A Kiick | 6 | 3 | 0 | 5 | I Bara | 6 | 6$^4$ | 3 | | | | | | | | | | |
| Q | A Anshba | 7 | 3 | 0 | Q | J Loeb | 4 | 7$^7$ | 6 | | | | | | | | | | |
| Q | J Loeb | 5 | 6 | 6 | | | | | | Q | J Loeb | 2 | 4 | | | | | | |
| SE | C Liu | 6 | 6 | | | | | | | SE | C Liu | 6 | 6 | | | | | | |
| WC | A Parks | 4 | 4 | | SE | C Liu | 6 | 6 | | | | | | | | | | | |
| Q | U Radwańska | 4 | 3 | | 3 | M Sherif | 3 | 0 | | | | | | | | | | | |
| 3 | M Sherif | 6 | 6 | | | | | | | | | | | | SE | C Liu | 4 | 6 | 6 |
| 7 | O Govortsova | 6 | 7 | | | | | | | | | | | | | H Dart | 6 | 3 | 3 |
| Q | A Krunić | 3 | 5 | | 7 | O Govortsova | 7 | 0 | 6 | | | | | | | | | | |
| | C Dolehide | 1 | 6 | 4 | Q | A Sutjiadi | 5 | 6 | 4 | | | | | | | | | | |
| Q | A Sutjiadi | 6 | 2 | 6 | | | | | | 7 | O Govortsova | 7$^7$ | 3 | 4 | | | | | |
| Q | A Hartono | 1 | 6 | 4 | | | | | | | H Dart | 6$^5$ | 6 | 6 | | | | | |
| | Ar Rodionova | 6 | 2 | 6 | | Ar Rodionova | 6$^3$ | 6 | 1 | | | | | | | | | | |
| | H Dart | 6$^5$ | 6 | 6 | | H Dart | 7$^7$ | 4 | 6 | | | | | | | | | | |
| 2/WC | C McNally | 7$^7$ | 4 | 3 | | | | | | | | | | | | | | | |