OpenLLM-France/wikimedia huggingface dataset:
# Janus kinase 3 deficiency

JAK3 (Janus kinase 3) deficiency is a dysfunction in cytokine receptor signalling and their production of cytokines.
JAK3 is a tyrosine protein kinase, an enzyme that is encoded by the JAK3 gene. It is a kinase that is activated only by cytokines whose receptors contain the common gamma chain subunit (IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21). JAK3 is involved in initiating signalling for the cytokine receptors because they itself lack enzymatic activity. Once activated, the JAK kinase phosphorylates specific tyrosine residues on the cytokine receptor subunits which then activate STAT transcription factors. JAK3 helps to regulate differentiation and maturation of B cells, T cells and NK cells.
Mutations in the JAK3 gene can cause dysfunction of the kinase leading to autosomal severe combined immunodeficiency (SCID) disease or on the contrary, the activation of mutated JAK3 can lead to development of leukemia. The JAK3 tyrosine kinase is mutated in 10% to 16% of T-cell acute lymphoblastic leukemia (T-ALL) cases.
Patients with JAK3-deficiency lack the necessary immune cells, meaning that they do not have T cells and NK cells but have normal level but poorly functioning B cells. The necessary immune cells have resistance and ability to fight off certain bacteria, viruses, and fungi. The patients are then prone to repeated and persistent infections that can be very serious or life-threatening.
Affected infants typically develop chronic diarrhea, a fungal infection in the mouth called oral thrush (candidiasis), pneumonia, and skin rashes. Constant illness also causes slower development of the affected individuals. Without treatment, people with JAK3-deficient SCID usually live only into early childhood.

## Diagnosis

In suspection of a genetic mutation after physical examination, checking personal and family medical history and laboratory tests (measuring levels of certain substances or biochemical test of the blood and urine) can be used genetic testing as certain diagnosis. Genetic testing identifies changes in chromosomes, genes, or proteins. However, some conditions do not have a specific genetic test; either the genetic cause of the condition is unknown or a test has not yet been developed. In these cases, a combination of the approaches listed above may be used to make a diagnosis.

## Treatment

The treatment for JAK3 deficiency is allogeneic hematopoietic stem cell transplantation, which has been demonstrated to be life-saving for affected patients.
Another option is gene therapy that has the potential to become an alternative treatment for JAK3 deficiency. Because of the clinical and biochemical similarities between JAK3 deficiency and X-linked severe combined immunodeficiency, genetic correction and engraftment of autologous hematopoietic stem cells can presume restoring of immunity in JAK3-deficient patients.
# Becraft Formation

The Becraft Formation is a geologic formation of marine sedimentary rock found in New York State. The Becraft is a part of the lower Devonian Helderberg Group and conformably overlies the New Scotland Formation and is overlain by the Alsen Formation throughout the lower Hudson Valley of New York State. The formation is Gedinnian in age. Outcrops of the formation are found from the New York-New Jersey border to the Helderbergs of Albany County, New York and as far west as Schoharie County, New York. The thickness of the formation varies from around 3 meters in Canajoharie to 8 meters thick in Albany and swells to 27 meters near Kingston. The Becraft Formation is named for Becraft Mountain in western Columbia County, New York where it prominently crops out.

## Geology
### Description

The Becraft Formation is a coarse limestone with occasional thin interbedded shale layers. Individual limestone beds within the formation range from 5 to 15 centimeters in thickness, while the shale horizons are up to 3 centimeters thick. Chert nodules are found near the top of the formation. The limestone which constitutes the bulk of the formation is pinkish grey in color and contains abundant invertebrate fossils including brachiopods and crinoids. The Becraft is a grainstone in Dunham classification. Recently the Helderberg Group, of which the Becraft Formation is a member, has been investigated as a possible geologic seal for subsurface carbon dioxide sequestration efforts.

### Deposition

The Becraft Formation was likely deposited in a shallow, high-energy marine environment similar to the depositional environment of the Coeymans Formation which underlies the Becraft within the Helderberg Group. After the mountain building events of the Taconic Orogeny around 440 million years ago, the eastern edge of North America became a passive margin. During this period in the Early Devonian, much of the Appalachian Basin was flooded with seawater producing a shallow, tropical marine environment. The Becraft Formation was deposited as part of a carbonate platform which developed within this basin prior to the onset of the Acadian orogeny in the Middle Devonian.
# Gallio, Veneto

Gallio (Cimbrian: Ghèl) is a town in the province of Vicenza, Veneto, Italy. It is on SP76. As of 2007 Gallio had an estimated population of 2,454.
The town is home to mountain slopes popular with skiers, and a 70-meter ski jump, which has been used in international ski jumping competitions.

## Sources

* (Google Maps)
* ↑ "Superficie di Comuni Province e Regioni italiane al 9 ottobre 2011". Italian National Institute of Statistics. Retrieved 16 March 2019.
* ↑ All demographics and other statistics from the Italian statistical institute (Istat)
* ↑ "The World Gazetteer". Archived from the original on 2007-10-01. Retrieved 2007-02-21.
* ↑ Fodor's Travel Publications, Italy on the Loose (1995), p. 73.
* This article on a location in Veneto is a stub. You can help Wikipedia by expanding it.
* v
* t
* e
# Richard Friar

Richard "Ric" Friar is an English-Australian big wave surfer, artist, peace activist, film-maker and horticulturist. He is known as a pioneer of commercial cannabis (hemp) cultivation in Australia.

## Big wave surfing

Friar is considered a pioneer of 1960s big wave surfing. In 1966, he was among the first to surf the Cribbar off Towan Head in the United Kingdom, along with Peter Russell, John McIlroy and American Jack Lydgate, during that year's Great September Swell. In 2013, Friar contacted locals in Newquay with plans to reunite the group of 1966 Cribbar surfers for the 2016 unveiling of a monument and a "celebration of British surfing" event. He has also announced his and his partner, Wendy Harper's, plans to establish the "International Surfing Pilgrim's Trail" and a "global sustainability project" called 1GiantWave.

## Horticulture

In the early 1990s, Friar was humorously dubbed the "King of Poo" by the Sydney Morning Herald's quirky Column 8 for his disposal of manure for the Agricultural Society at the Sydney Royal Easter Show. He continued to pioneer the use of worms, mulch and manure in horticulture and established a business selling related products.
In 2009, Friar received permission from the New South Wales Department of Primary Industries for a pilot program to study the potential commercialisation of hemp. Friar cultivated 500 cannabis plants and suggested potential applications in the "textile and construction industries". The pilot would also allow consideration of applications including automotive fibreglass, paper and biofuel. Friar said Government fears about psychoactive cannabis had put a stop to what had once been among the world's largest crops.

## Film making and art

Having semi-retired, Friar and partner Wendy Harper have produced a number of short films about their commercial endeavours and general interests. In 2007, they produced an hour-long documentary about the anti-war movement in Australia and parallels between it and the Australian Aboriginal indigenous rights movement. Called Think About It!, the documentary starred indigenous actor David Gulpilil and included commentary from former Prime Minister, Malcolm Fraser, former Greens leader, Bob Brown, and Terry Hicks, father of Guantanamo Bay detainee David Hicks. In 2009, Friar produced a short film detailing the social aspects of railway history in Western New South Wales.
In 2011, Friar and Harper collaborated with two-time Wynne Prize winner Ian Bettinson to create a series of semi-abstract artworks and poetry. Over three weeks, the artists jointly created 30 works of art that were subsequently featured at the live exhibition version of Grand Designs Australia. The paintings were displayed with corresponding poetic works written by Harper.
Friar is known for using wood ash and other unusual artistic mediums as well as bark, leaves and grass in place of paint brushes. Also in 2011, Friar controversially used the ashes from his son's cremation to create a series of artworks as a tribute. He now produces similar artworks for others.
# Francis Moorehouse

Francis C. "Skip" Moorehouse (May 1, 1923 - March 17, 1982) was an American labor relations specialist who worked for General Electric and served as Town Manager of Saugus, Massachusetts.

## Early life

Moorehouse was born in Pascoag, Rhode Island. He graduated from Saugus High School in 1941 and went on to attend Lowell Institute and Mississippi State College.
Moorehouse served in the United States Army during World War II. For 13 years, he was a member of the Massachusetts National Guard, where he retired as a captain.

## General Electric

Moorehouse worked for the General Electric plant in Lynn, Massachusetts, for 34 years. From 1953 to 1982 he was the manager of union relations, representing GE in union negotiations.

## Saugus Town Manager

In 1970, Moorehouse took a sabbatical from General Electric to serve as Town Manager of Saugus. He was the first Saugus resident to ever serve as full-time town manager. During his tenure he dealt with youth crime, attempted to have a $190 million oil refinery built in town, and succeeded in having Wheelabrator Technologies build their incineration plant, which would become the first commercially successful incineration plant in the United States, in Saugus. He is best remembered, however, for his proposal to bring sewers to Saugus.
In 1973, Moorehouse's sabbatical ended and he chose to return to General Electric rather than remain as town manager.

## Death

Moorehouse died on March 17, 1982, after a brief illness.
# Rönne (river)

56°14′10″N 12°55′09″E﻿ / ﻿56.23613°N 12.91905°E﻿ / 56.23613; 12.91905
The Rönne (Swedish: Rönne å) is a river in Scania, Sweden with a length of 83 kilometers. The Rönne flows from Ringsjön and opens into Skälderviken in Ängelholm.
# Harmonyville, Pennsylvania

Harmonyville is a populated place situated in Warwick Township in Chester County, Pennsylvania, United States. It has an estimated elevation of 492 feet (150 m) above sea level.
# Fomitopsis palustris

Fomitopsis palustris is a species of polypore fungus in the family Fomitopsidaceae. It causes brown rot, a disease of wood that results from the enzymatic breakdown of the wood component cellulose, but not lignin. Several enzymes involved in the wood-decay process have been biochemically characterized. The whole genome sequence of F. palustris was reported in 2017.

## Wood decay enzymes

Fomitopsis palustris is known to possess three different cellulase enzymes.
An endoglucanase, named EG-II, has been purified and characterized from this species in 2008; it is believed to assist in the wood rot process by loosening the polysaccharide network in cell walls by disentangling hemicelluloses associated with cellulose.
# Piotr Łossowski

Piotr Łossowski (born 25 February 1925) is a Polish historian and professor. Lecturer at Collegium Civitas. Member of the Historical Committee of Polish Academy of Sciences. He specializes in the areas of foreign politics and diplomacy and history of the Second Polish Republic, military history of Poland in the years 1918–1920, history of the Baltic states and their relations with Poland. He gained major recognition for his works on the state of Polish diplomacy in the time of the Second Republic.
Editor in chief of Studia z Dziejów Rosji i Europy Środkowej-Wschodniej (Studies the History of Russia and East-Central Europe) journal.

## Selected publications

* Agresja hitlerowska na Polskę (1964)
* Stosunki polsko-litewskie 1918–1920 (1966)
* Żołnierze minionych lat (1969)
* Kraje bałtyckie na drodze od demokracji parliamentarnej do dyktatury (1972)
* Między wojną a pokojem (1976)
* Litwa a sprawy polskie 1939–1949 (1982)
* Po tej i po tamtej stronie Niemna: Stosunki polsko-litewskie 1883–1939 (1985)
* Zerwane pęta: Usunięcie okupantów z ziem polskich w listopadzie 1918 (1986)
* Polska w Europie i świecie (1992)
* Stosunki polsko-estońskie (1992)
* Historia dyplomacji polskiej, t.4 (red.) (1995)
* Konflikt polsko-litewski 1918–1920 (1996)
* Stosunki polsko-litewskie 1921–1939 (1997)
* Jak Feniks z popiołów. Oswobodzenie ziem polskich spod okupacji (1998)
* Litwa / Historia państw świata XX wieku (2001)
* Dyplomacja polska 1918–1939 (2001)
# Plastic in art

Within the 20th century, there came the use of plastics in art. In the latter half of the century, plastic technology advanced so that it was feasible for artists to start using plastic and acrylics as an artwork medium.

## Using found plastic

Art made of commodity materials sometimes uses found objects made of plastic. Plastic containers are useful in papier-mâché for building frames.
Environmental artists are using salvaged beach plastic to create art as a means of bringing awareness of plastic pollution in Earth's oceans. Examples include: Judith Selby Lang and Richard Lang, members of Women Eco Artists Dialog, and the photography of Chris Jordan.

## Use of liquid acrylics

Liquid acrylics can be used to create two- and three-dimensional plastic images and objects. Artist, Tyler Turkle, pours multiple thin layers of pigmented liquid acrylic to form sheets of plastic that result in paintings and sculptures. After adequate drying time between applications, these solid plastic sheets can be readily peeled off most surfaces and re-adhered to others.

## Gallery

* Saytour Torchons Nîmes
* "MasterCard/Visa (If it wasn’t for plastic money I wouldn’t have any money at all)", poured acrylic, Tyler Turkle, 2006
* Milton Becerra Ale'ya Durban Segnini Gallery Miami 2009.
* Bois de Belle Rivière Québec 2010
* Sarabande Musée des Tissus Lyon 2007-2008
# Lone Willow Station

Lone Willow Station was a former settlement in Merced County, California, located near present-day Los Banos.

## Background

Lone Willow Station was a changing or swing station along the First Division route of the Butterfield Overland Mail, from 1858 to 1861. Lone Willow Station was located on the west bank of Mud Slough, 18 miles east of the St. Louis Ranch Station and 13 miles northwest of Temple's Ranch Station. This station consisted of a house for the hostler and a large barn for the relay horses and storage of their barley and hay.
# Galliobatidae

Galliobatidae is a family of millipedes belonging to the order Julida.
Genera:
# Hodaghatta

Hodaghatta is a village situated in Mandya Taluk, Mandya district, Karnataka, India. The 2011 India Census records a population of 1,152 for Hodaghatta. It has pincode 571450. The village of Echagere is one kilometre (0.6 mile) to the south-east.
# Francis Moore (Medal of Honor)

Francis Moore (born 1858, date of death unknown) was a United States Navy sailor and a recipient of the United States military's highest decoration, the Medal of Honor.

## Biography

Born in 1858 in New York County, New York, Moore joined the Navy from that state. By January 23, 1882, he was serving as a boatswain's mate on the training ship USS Portsmouth. On that day, while Portsmouth was at the Washington Navy Yard, Moore jumped overboard in an attempt to rescue carpenter and caulker, Thomas Duncan, who had fallen overboard, from drowning. For this action, he was awarded the Medal of Honor three years later, on October 18, 1884.
Moore's official Medal of Honor citation reads:
   For jumping overboard from the U.S. Training Ship Portsmouth, at the Washington Navy Yard, 23 January 1882, and endeavoring to rescue Thomas Duncan, carpenter and calker, who had fallen overboard.
# Joseph Parsons Jr.

Joseph Parsons Jr. (1647–1729) was an early settler and prominent colonial leader in Northampton, Massachusetts.
Parsons Jr. was born in Springfield, Massachusetts on November 1, 1647. His father, Cornet Joseph Parsons Sr., immigrated to America from England around 1635, and was one of the witnesses to the deed that transferred ownership of Springfield from the Native Americans to the English settlers. He later became one of the original settlers of Northampton, Massachusetts. Parson Jr.'s mother, Mary (Bliss) Parsons was accused of witchcraft several decades before the far more notorious Salem Witch Trials, although she was ultimately acquitted.
Parsons Jr. lived most of his life in Northampton. On March 17, 1669, he married Elizabeth Strong, the daughter of John Strong, the lead elder of the church and prominent resident of the town. Parsons Jr. was involved in several business enterprises in and around Northampton, including grist mills, sawmills, and iron. He later became active in politics; in 1696, he was commissioned as one of the four judges on the Hampshire County Court of Common Pleas, which at the time included all of Western Massachusetts. He served in this capacity until 1719. Parsons Jr. also served as a representative in the Massachusetts General Court; he represented Springfield in 1706 and 1708, and Northampton from 1711-1715, 1717, 1721, and 1724. In addition, he held several other minor offices; in 1700, he was appointed as the first town moderator in Northampton history, and he also served as justice of the peace for a number of years.
Throughout most of Parson Jr.'s life in Northampton, Solomon Stoddard was the pastor of the church. However, by 1725 Stoddard was 82 years old and unable to fulfill all of his pastoral duties alone. So, the town voted seven members onto a committee to find a suitable candidate to assist, and upon Stoddard's death, replace him as pastor. Joseph Parsons Jr. was one of the members of this pastoral search committee, which ultimately chose Jonathan Edwards, whose tenure as pastor would lead to the Great Awakening.
Joseph Parsons Jr. died in Northampton in November, 1729.
# Blue Cheer (album)

Blue Cheer is the fourth album by American rock band Blue Cheer. It was recorded at Wally Heider Studios in San Francisco and released in December 1969 by Philips Records. Gary Lee Yoder contributed songwriting for the opening and closing tracks and would later join the group as guitarist on their next album The Original Human Being.

## Release and reception

Professional ratings :
| Review scores ||
| Source | Rating |
| AllMusic | |
| Robert Christgau | B |
According to Lillian Roxon's Rock Encyclopedia, the album was released in December 1969. Reviewing for The Village Voice the following June, Robert Christgau gave the album a "B" grade and wrote: "There ought to be hundreds of groups like this one—hard, competent, slightly commercial—but there probably aren't more than 20. This is not especially original, but it's good, and I'll bet they're a stone happy gas live." AllMusic's Mark Deming later gave it three-and-a-half out of five stars and appraised it in comparison to the band's harder previous records, calling it "a fun album that generates an impressive groove ... a more laid-back and relaxed effort, but it still rocks with a strong and steady roll."

## Track listing
### Side one

* "Fool" (Gary R. Grelecki, Gary Lee Yoder) – 3:26
* "You're Gonna Need Someone" (Norman Mayell, Bruce Stephens) – 3:31
* "Hello LA, Bye Bye Birmingham" (Delaney Bramlett, Mac Davis) – 3:29
* "Saturday Freedom" (Stephens) – 5:47
* "Ain't That the Way (Love's Supposed to Be)" (Ralph Burns Kellogg, Dickie Peterson) – 3:11

### Side two

* "Rock and Roll Queens" (Kellogg, Peterson) – 2:44
* "Better When We Try" (Kellogg) – 2:48
* "Natural Man" (Kellogg, Peterson) – 3:36
* "Lovin' You's Easy" (Stephens) – 3:50
* "The Same Old Story" (Grelecki, Yoder) – 3:53
The 2007 Japanese mini-LP sleeve reissue of Blue Cheer contains the mono non-LP single "All Night Long" (Kellogg) b/w "Fortunes" (Peterson) along with the single versions of "Fool" and "Ain't That the Way" as bonus tracks.

## Personnel
### Blue Cheer

* Bruce Stephens – guitar, backing and lead (2, 4, 7, 9) vocals
* Dickie Peterson – bass, lead vocals (1, 3, 5, 6, 8, 10)
* Ralph Burns Kellogg – keyboards
* Norman Mayell – drums

### Production

* Michael Sunday – producer
* Eric Albronda – assistant producer, backing vocals
* John Craig – cover design
* Russ Gary – engineering
* Richard Germinaro – liner note art
* Baron Wolman – photography
# 1CMS

FM 91.1 CMS (callsign 1CMS) is a multilingual community radio station broadcasting to Canberra, in languages other than English, from studios in the suburb of Holder. CMS is a member of the National Ethnic and Multicultural Broadcasters Council (NEMBC) and the Community Broadcasting Association of Australia (CBAA).
The policy of CMS is to encourage all languages to broadcast for at least an hour each week, providing time on an equitable basis. Programming priorities include youth, women and emerging communities.

## History

The EBC (Ethnic Broadcasters Council) as it was then called, started broadcasting by purchasing airtime on community station 2XX. Up to 25 language groups were broadcasting for half an hour each per week during the 1980s. Discontent in the early 1990s saw the EBC and 2XX sever ties with each other. EBC were off the air until August 1992 when they were able to apply for their own test broadcast licence. EBC were back on air on Tuesdays and Fridays using the facilities of ArtSound FM.
In 1999 the EBC received a full-time test licence to broadcast on 103.5 FM. Soon after the on air identity was changed to Canberra Multicultural Service and the frequency moved to the present 91.1 FM. Then an application for a full broadcasting licence was applied for. This was granted on 15 June 2001.

## Current

FM 91.1 CMS now has programming in around 30 languages. The station broadcasts live from the Canberra Multicultural Festival each year. Internet streaming was introduced in 2008.

## Programming

As of 2008, the station broadcasts in the following languages:
* Bosnian
* Cantonese
* Chilean Spanish
* Croatian
* Cypriot Greek
* Dutch
* Persian
* Belgian Dutch (Flemish)
* French
* German
* Greek
* Hindi
* Indonesian
* Italian
* Lao
* Macedonian
* Mandarin
* Motu/Pigin
* Polish
* Samoan
* Serbian
* Sinhalese
* Slovenian
* Spanish
* Swiss German
* Tamil
* Telugu
* Thai
* Tongan
* Urdu
* Vietnamese
Satellite programming from Deutsche Welle, Radio France International and the National Indigenous Radio Service is also carried.
# Fomitiporia mediterranea

Fomitiporia mediterranea is a fungus species in the genus Fomitiporia associated with esca of grapevine.
# Palazzo Tantucci

The Palazzo Tantucci is a Renaissance style (more specifically Mannerist) urban palace localized on Via dei Montanini, on the Piazza Salimbeni, in the Terzo di Camollia, in the city of Siena, region of Tuscany, Italy. To the palace's right is the Gothic facade of the Palazzo Salimbeni, and across the Piazza with Sallustio Bandini's statue is the Classic Renaissance facade of the Palazzo Spannocchi. All three palaces are owned now by the Monte dei Paschi di Siena, the oldest bank in the world, which arose in the Salimbeni palace. 43°19′17″N 11°19′50″E﻿ / ﻿43.321256°N 11.33054°E﻿ / 43.321256; 11.33054

## History

Construction of the palace in 1548 was commissioned by Mariano Tantucci from the artist Bartolomeo Neroni. The interiors underwent a series of reconstructions, including one by Giuseppe Partini in the 19th century. Since 1868, it has housed offices of the Banca Monte dei Paschi di Siena, and it was linked to the adjacent palaces in the 1970s by Pierluigi Spadolini.