# Signaling peptide receptor

Signaling peptide receptor is a type of receptor which binds one or more signaling peptides or signaling proteins.
An example is the tropomyosin receptor kinase B (TrkB), which is bound and activated by the neurotrophic protein brain-derived neurotrophic factor (BDNF). Another example is the μ-opioid receptor (MOR), which is bound and activated by the opioid peptide hormone β-endorphin.

## Adiponectin receptor
### AdipoR$_1$

* Agonists
** Peptide
*** Adiponectin
*** ADP-355
*** ADP-399
** Non-peptide
*** AdipoRon
*** (–)-Arctigenin
*** Arctiin
*** Gramine
*** Matairesinol
* Antagonists
** Peptide
*** ADP-400

### AdipoR$_2$

* Agonists
** Peptide
*** Adiponectin
*** ADP-355
*** ADP-399
** Non-peptide
*** AdipoRon
*** Deoxyschizandrin
*** Parthenolide
*** Syringing
*** Taxifoliol
* Antagonists
** Peptide
*** ADP-400

## Bradykinin receptor

* Agonists
** Bradykinin
** Kallidin
* Antagonists
** FR-173657
** Icatibant
** LF22-0542

## Calcitonin gene-related peptide receptor

* Agonists
** Amylin
** CGRP
** Pramlintide
* Antagonists
** Atogepant
** BI 44370 TA
** CGRP (8-37)
** MK-3207
** Olcegepant
** Rimegepant
** SB-268262
** Telcagepant
** Ubrogepant
* Antibodies
** Eptinezumab
** Erenumab
** Fremanezumab
** Galcanezumab

## Cholecystokinin receptor
### CCK$_A$

* Agonists
** Cholecystokinin
* Antagonists
** Amiglumide
** Asperlicin
** Devazepide
** Dexloxiglumide
** Lintitript
** Lorglumide
** Loxiglumide
** Pranazepide
** Proglumide
** Tarazepide
** Tomoglumide

### CCK$_B$

* Agonists
** Cholecystokinin
** CCK-4
** Gastrin
** Pentagastrin (CCK-5)
* Antagonists
** Ceclazepide
** CI-988 (PD-134308)
** Itriglumide
** L-365,360
** Netazepide
** Proglumide
** Spiroglumide

### Unsorted

* Antagonists
** Nastorazepide

## Corticotropin-releasing hormone receptor
### CRF$_1$

* Agonists
** Cortagine
** Corticorelin
** Corticotropin-releasing hormone
** Sauvagine
** Stressin I
** Urocortin
* Antagonists
** Antalarmin
** Astressin-B
** CP-154,526
** Emicerfont
** Hypericin
** LWH-234
** NBI-27914
** NBI-74788
** Pexacerfont
** R-121919
** TS-041
** Verucerfont

### CRF$_2$

* Agonists
** Corticorelin
** Corticotropin-releasing hormone
** Sauvagine
** Urocortin
* Antagonists
** Astressin-B

## Endothelin receptor

* Agonists
** Endothelin 1
** Endothelin 2
** Endothelin 3
** IRL-1620
** Sarafotoxin
* Antagonists
** A-192621
** Ambrisentan
** Aprocitentan
** Atrasentan
** Avosentan
** Bosentan
** BQ-123
** BQ-788
** Clazosentan
** Darusentan
** Edonentan
** Enrasentan
** Fandosentan
** Feloprentan
** Macitentan
** Nebentan
** Sitaxentan
** Sparsentan
** Tezosentan
** Zibotentan

## Galanin receptor
### GAL$_1$

* Agonists
** Galanin
** Galanin (1-15)
** Galanin-like peptide
** Galmic
** Galnon
** NAX 810-2
* Antagonists
** C7
** Dithiepine-1,1,4,4-tetroxide
** Galantide (M15)
** M32
** M35
** M40
** SCH-202596

### GAL$_2$

* Agonists
** Galanin
** Galanin (1-15)
** Galanin (2-11)
** Galanin-like peptide
** Galmic
** Galnon
** J18
** NAX 810-2
* Antagonists
** C7
** Galantide (M15)
** M32
** M35
** M40
** M871

### GAL$_3$

* Agonists
** Galanin
** Galanin (1-15)
** Galmic
** Galnon
* Antagonists
** C7
** Galantide (M15)
** GalR3ant
** HT-2157
** M32
** M35
** M40
** SNAP-37889
** SNAP-398299

## Glucagon-like peptide receptor
### GLP-1

* Agonists
** Albiglutide
** Beinaglutide
** Dulaglutide
** Efpeglenatide
** Exenatide
** GLP-1
** Langlenatide
** Liraglutide
** Lixisenatide
** Oxyntomodulin
** Pegapamodutide
** Semaglutide
** Taspoglutide

### GLP-2

* Agonists
** Apraglutide
** Elsiglutide
** Glepaglutide
** GLP-2
** Teduglutide

### Others

* Propeptides
** Preproglucagon
** Proglucagon

## Glucagon receptor

* Agonists
** Dasiglucagon
** Glucagon
** Oxyntomodulin
* Antagonists
** Adomeglivant
** L-168,049
** LGD-6972
* Propeptides
** Preproglucagon
** Proglucagon

## Insulin receptor

* Agonists
** Chaetochromin (4548-G05)
** Insulin-like growth factor 1
** Insulin-like growth factor 2
** Insulin
** Insulin aspart
** Insulin degludec
** Insulin detemir
** Insulin glargine
** Insulin glulisine
** Insulin lispro
** Mecasermin
** Mecasermin rinfabate
* Antagonists
** BMS-754807
** S661
** S961
* Kinase inhibitors
** Linsitinib
* Antibodies
** Xentuzumab (against IGF-1 and IGF-2)

## KiSS1-derived peptide receptor

* Agonists
** Kisspeptin (kisspeptin-54, metastin)
** Kisspeptin-10
** KISS1-305
** MVT-602 (RVT-602, TAK-448)
** TAK-683
* Antagonists
** Kisspeptin-234

## Leptin receptor

* Agonists
** Leptin
** Metreleptin

## Melanin-concentrating hormone receptor
### MCH$_1$

* Agonists
** Melanin-concentrating hormone
* Antagonists
** ATC-0065
** ATC-0175
** GW-803430
** NGD-4715
** SNAP-7941
** SNAP-94847

### MCH$_2$

* Agonists
** Melanin-concentrating hormone

## Neuropeptide FF receptor

* Agonists
** Neuropeptide AF
** Neuropeptide FF
** Neuropeptide SF (RFRP-1)
** Neuropeptide VF (RFRP-3)
* Antagonists
** BIBP-3226
** RF9

## Neuropeptide S receptor

* Agonists
** Neuropeptide S
* Antagonists
** ML-154
** SHA-68

## Neuropeptide Y receptor
### Y$_1$

* Agonists
** Neuropeptide Y
** Peptide YY
* Antagonists
** BIBO-3304
** BIBP-3226
** BVD-10
** GR-231118
** PD-160170

### Y$_2$

* Agonists
** 2-Thiouridine 5'-triphosphate
** Neuropeptide Y
** Neuropeptide Y (13-36)
** Peptide YY
** Peptide YY (3-36)
* Antagonists
** BIIE-0246
** JNJ-5207787
** SF-11

### Y$_4$

* Agonists
** GR-231118
** Neuropeptide Y
** Pancreatic polypeptide
** Peptide YY
* Antagonists
** UR-AK49

### Y$_5$

* Agonists
** BWX-46
** Neuropeptide Y
** Peptide YY
* Antagonists
** CGP-71683
** FMS-586
** L-152,804
** Lu AA-33810
** MK-0557
** NTNCB
** Velneperit (S-2367)

## Neurotensin receptor
### NTS$_1$

* Agonists
** Neurotensin
** Neuromedin N
* Antagonists
** Meclinertant
** SR-142948

### NTS$_2$

* Agonists
** Neurotensin
* Antagonists
** Levocabastine
*** SR-142948

## Parathyroid hormone receptor

* Agonists
** Abaloparatide
** Parathyroid hormone
** Parathyroid hormone-related protein (PTHrP)
** Semparatide
** Teriparatide

## Relaxin receptor

* Agonists
** Insulin-like factor 3
** Relaxin (1, 2, 3)
** Serelaxin

## Thyrotropin-releasing hormone receptor

* Agonists
** Azetirelin
** JTP-2942
** Montirelin
** Orotirelin
** Posatirelin
** Protirelin
** Rovatirelin
** RX-77368 (thymoliberin)
** Taltirelin
** TRH (TRF)

## Thyrotropin receptor

* Agonists
** Thyrotropin alfa
** TSH (thyrotropin)

## Vasoactive intestinal peptide receptor and Pituitary adenylate cyclase-activating peptide
### VIPR$_1$

* Agonists
** Peptide
*** Bay 55-9837
*** LBT-3393
*** PACAP
*** VIP

### VIPR$_2$

* Agonists
** Peptide
*** LBT-3627
*** PACAP
*** VIP

### PAC$_1$

* Agonists
** PACAP
** PACAP (1-27)
** PACAP (1-38)
* Antagonists
** PACAP (6-38)

### Unsorted

* PHI
* PHM
* PHV

## Others

* Endogenous
** Adrenomedullin
** Apelin
** Asprosin
** Bombesin
** Calcitonin
** Carnosine
** CART
** CLIP
** DSIP
** Enteroglucagon
** Formyl peptide
** GALP
** GIP
** GRP
** Integrin ligands
*** collagens
*** fibrinogen
*** fibronectin
*** laminins
*** ICAM-1
*** ICAM-2
*** osteopontin
*** VCAM-1
*** vitronectin
** Kininogens
** Motilin
** Natriuretic peptides
*** ANP
*** BNP
*** CNP
*** urodilatin
** Nesfatin-1
** Neuromedin B
** Neuromedin N
** Neuromedin S
** Neuromedin U
** Obestatin
** Osteocalcin
** Resistin
** Secretin
** Thymopoietin
** Thymosins
** Thymulin
** Urotensin-II
** VGF
* Exogenous
** Lifitegrast (LFA-1 antagonist)