# 2021 Kuchyně Gorenje Prague Open – Singles

Jana Čepelová was the defending champion but chose not to participate.
Magdalena Fręch won the title, defeating Tereza Smitková in the final, 6–2, 6–1.

## Seeds

* Magdalena Fręch (champion)
* Katarzyna Kawa (second round)
* Panna Udvardy (first round)
* Leonie Küng (first round)
* Lucia Bronzetti (second round)
* Rebecca Šramková (quarterfinals)
* Lucrezia Stefanini (first round)
* Diane Parry (semifinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 1 | Magdalena Fręch | 6 | 6 | | | | |
| 8 | Diane Parry | 3 | 3 | | | | |
| 8 | Diane Parry | 3 | 3 | 1 | Magdalena Fręch | 6 | 6 |
| | | | | Q | Tereza Smitková | 2 | 1 |
| | Daniela Vismane | 4 | 3 | Q | Tereza Smitková | 2 | 1 |
| Q | Tereza Smitková | 6 | 6 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | M Fręch | 7 | 6 | | | | | | | | | | | | | | |
| | J Malečková | 5 | 1 | | 1 | M Fręch | 7$^7$ | 6 | | | | | | | | | |
| | A Ignatik | 6 | 6 | | | A Ignatik | 6$^3$ | 3 | | | | | | | | | |
| Q | V Strakhova | 2 | 1 | | | | | | | 1 | M Fręch | 7$^7$ | 6 | | | | |
| WC | L Nosková | 7 | 6 | | | | | | | WC | L Nosková | 6$^6$ | 2 | | | | |
| WC | D Viďmanová | 5 | 1 | | WC | L Nosková | 6$^5$ | 6 | 7 | | | | | | | | |
| | G Cé | 6$^4$ | 7$^7$ | 1 | 5 | L Bronzetti | 7$^7$ | 4 | 5 | | | | | | | | |
| 5 | L Bronzetti | 7$^7$ | 6$^2$ | 6 | | | | | | | | | | 1 | M Fręch | 6 | 6 |
| 3 | P Udvardy | 3 | 1 | | | | | | | | | | | 8 | D Parry | 3 | 3 |
| Q | L Glushko | 6 | 6 | | Q | L Glushko | 3 | 6 | 7$^8$ | | | | | | | | |
| | R Hogenkamp | 6 | 0 | 2 | | A Hartono | 6 | 2 | 6$^6$ | | | | | | | | |
| | A Hartono | 4 | 6 | 6 | | | | | | Q | L Glushko | 1 | 3 | | | | |
| | N Stevanović | 6$^5$ | 7$^{10}$ | 6 | | | | | | 8 | D Parry | 6 | 6 | | | | |
| WC | M Kilnarová | 7$^7$ | 6$^8$ | 2 | | N Stevanović | 3 | 1 | | | | | | | | | |
| | M Kolodziejová | 7$^7$ | 3 | 4 | 8 | D Parry | 6 | 6 | | | | | | | | | |
| 8 | D Parry | 6$^5$ | 6 | 6 | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | R Šramková | 7 | 6 | | | | | | | | | | | | | | |
| Q | A Gabric | 5 | 1 | | 6 | R Šramková | 6 | 6 | | | | | | | | | |
| Q | M Kawamura | 7 | 3 | 6 | Q | M Kawamura | 1 | 2 | | | | | | | | | |
| Q | A Bozovic | 5 | 6 | 4 | | | | | | 6 | R Šramková | 2 | 5 | | | | |
| | Z Zlochová | 0 | 3 | | | | | | | | D Vismane | 6 | 7 | | | | |
| Q | T Cvetkovič | 6 | 6 | | Q | T Cvetkovič | 3 | 0 | | | | | | | | | |
| | D Vismane | 6 | 6 | | | D Vismane | 6 | 6 | | | | | | | | | |
| 4 | L Küng | 3 | 4 | | | | | | | | | | | | D Vismane | 4 | 3 |
| 7 | L Stefanini | 2 | 6$^2$ | | | | | | | | | | | Q | T Smitková | 6 | 6 |
| | S-j Jang | 6 | 7$^7$ | | | S-j Jang | 6 | 6$^1$ | 1 | | | | | | | | |
| WC | S Bejlek | 6$^4$ | 6 | 6 | WC | S Bejlek | 2 | 7$^7$ | 6 | | | | | | | | |
| | M Di Giuseppe | 7$^7$ | 3 | 3 | | | | | | WC | S Bejlek | 3 | 2 | | | | |
| Q | T Smitková | 6 | 3 | 6 | | | | | | Q | T Smitková | 6 | 6 | | | | |
| Q | A Ramé | 2 | 6 | 3 | Q | T Smitková | 6 | 6$^4$ | 7$^7$ | | | | | | | | |
| | S Lamens | 1 | 2 | | 2 | K Kawa | 2 | 7$^7$ | 6$^4$ | | | | | | | | |
| 2 | K Kawa | 6 | 6 | | | | | | | | | | | | | | |