# 2016 Trofeo Città di Brescia – Singles

Igor Sijsling was the defending champion but chose not to defend his title.
Luca Vanni won the title after defeating Laurynas Grigelis 6–7$^{(5–7)}$, 6–4, 7–6$^{(10–8)}$ in the final.

## Seeds

* Lukáš Lacko (semifinals)
* Lukáš Rosol (withdrew)
* Marco Chiudinelli (second round)
* Evgeny Donskoy (first round)
* Leonardo Mayer (second round)
* Enrique López-Pérez (first round)
* Alexander Kudryavtsev (second round)
* Marko Tepavac (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| 1 | Lukáš Lacko | 6$^4$ | 4 | | | | | |
| | Luca Vanni | 7$^7$ | 6 | | | | | |
| | Luca Vanni | 7$^7$ | 6 | | Luca Vanni | 6$^5$ | 6 | 7$^{10}$ |
| | | | | LL | Laurynas Grigelis | 7$^7$ | 4 | 6$^8$ |
| | Salvatore Caruso | 4 | 4 | LL | Laurynas Grigelis | 7$^7$ | 4 | 6$^8$ |
| LL | Laurynas Grigelis | 6 | 6 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | L Lacko | 6 | 6 | | | | | | | | | | | | | | | |
| Q | Lukas Rüpke | 2 | 2 | | 1 | L Lacko | 6$^4$ | 7$^7$ | 6 | | | | | | | | | |
| WC | M Berrettini | 6 | 7$^7$ | | WC | M Berrettini | 7$^7$ | 6$^2$ | 4 | | | | | | | | | |
| | L Sonego | 4 | 6$^5$ | | | | | | | 1 | L Lacko | 6 | 6 | | | | | |
| WC | A Vavassori | 3 | 4 | | | | | | | | F Dancevic | 4 | 3 | | | | | |
| | F Dancevic | 6 | 6 | | | F Dancevic | 6 | 3 | 7$^{11}$ | | | | | | | | | |
| SE | K Krawietz | 6 | 6 | | SE | K Krawietz | 3 | 6 | 6$^9$ | | | | | | | | | |
| 6 | E López-Pérez | 4 | 4 | | | | | | | | | | | | 1 | L Lacko | 6$^4$ | 4 |
| 4 | E Donskoy | 4 | 6 | 3 | | | | | | | | | | | | L Vanni | 7$^7$ | 6 |
| PR | B Kavčič | 6 | 4 | 6 | PR | B Kavčič | 3 | 6 | 6$^4$ | | | | | | | | | |
| WC | S Travaglia | 5 | 3 | | | L Vanni | 6 | 4 | 7$^7$ | | | | | | | | | |
| | L Vanni | 7 | 6 | | | | | | | | L Vanni | 5 | 7$^9$ | 7$^7$ | | | | |
| | S Tsitsipas | 2 | 1 | | | | | | | WC | T Robredo | 7 | 6$^7$ | 6$^5$ | | | | |
| WC | T Robredo | 6 | 6 | | WC | T Robredo | 7 | 7 | | | | | | | | | | |
| | A Šetkić | 4 | 6$^7$ | | 7 | A Kudryavtsev | 5 | 5 | | | | | | | | | | |
| 7 | A Kudryavtsev | 6 | 7$^9$ | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | M Tepavac | 5 | 3 | | | | | | | | | | | | | | |
| | R Ramanathan | 7 | 6 | | | R Ramanathan | 4 | 5 | | | | | | | | | |
| | S Caruso | 6 | 4 | 6 | | S Caruso | 6 | 7 | | | | | | | | | |
| | M Zekić | 2 | 6 | 3 | | | | | | | S Caruso | 6 | 6 | | | | |
| Q | Petr Michnev | 4 | 1 | | | | | | | | Z Kolář | 4 | 2 | | | | |
| | Z Kolář | 6 | 6 | | | Z Kolář | 6 | 6 | | | | | | | | | |
| | L Giustino | 3 | 5 | | 3 | M Chiudinelli | 4 | 4 | | | | | | | | | |
| 3 | M Chiudinelli | 6 | 7 | | | | | | | | | | | | S Caruso | 4 | 4 |
| 5 | L Mayer | 6 | 6 | | | | | | | | | | | LL | L Grigelis | 6 | 6 |
| | F Škugor | 3 | 4 | | 5 | L Mayer | 6 | 6$^3$ | 5 | | | | | | | | |
| LL | L Grigelis | 3 | 6 | 7$^7$ | LL | L Grigelis | 3 | 7$^7$ | 7 | | | | | | | | |
| | A Arnaboldi | 6 | 3 | 6$^2$ | | | | | | LL | L Grigelis | 0 | | | | | |
| LL | G Mager | 6$^2$ | 6$^3$ | | | | | | | Q | E Gerasimov | 1$^r$ | | | | | |
| Q | Marek Jaloviec | 7$^7$ | 7$^7$ | | Q | M Jaloviec | 6$^6$ | 5 | | | | | | | | | |
| | A Santillan | 3 | 6$^4$ | | Q | E Gerasimov | 7$^8$ | 7 | | | | | | | | | |
| Q | E Gerasimov | 6 | 7$^7$ | | | | | | | | | | | | | | |