# Timeline of antibiotics

This is the timeline of modern antimicrobial (anti-infective) therapy. The years show when a given drug was released onto the pharmaceutical market. This is not a timeline of the development of the antibiotics themselves.
* 1911 – Arsphenamine, also Salvarsan
* 1912 – Neosalvarsan
* 1935 – Prontosil (an oral precursor to sulfanilamide), the first sulfonamide
* 1936 – Sulfanilamide
* 1938 – Sulfapyridine (M&B 693)
* 1939 – sulfacetamide
* 1940 – sulfamethizole
* 1942 – benzylpenicillin, the first penicillin
* 1942 – gramicidin S, the first peptide antibiotic
* 1942 – sulfadimidine
* 1943 – sulfamerazine
* 1944 – streptomycin, the first aminoglycoside
* 1947 – sulfadiazine
* 1948 – chlortetracycline, the first tetracycline
* 1949 – chloramphenicol, the first amphenicol
* 1949 – neomycin
* 1950 – oxytetracycline
* 1950 – penicillin G procaine
* 1952 – erythromycin, the first macrolide
* 1954 – benzathine penicillin
* 1955 – spiramycin
* 1955 – tetracycline
* 1955 – thiamphenicol
* 1955 – vancomycin, the first glycopeptide
* 1956 – phenoxymethylpenicillin
* 1958 – colistin, the first polymyxin
* 1958 – demeclocycline
* 1959 – virginiamycin
* 1960 – methicillin
* 1960 – metronidazole, the first nitroimidazole
* 1961 – ampicillin
* 1961 – spectinomycin
* 1961 – sulfamethoxazole
* 1961 – trimethoprim, the first dihydrofolate reductase inhibitor
* 1962 – oxacillin
* 1962 – cloxacillin
* 1962 – fusidic acid
* 1963 – fusafungine
* 1963 – lymecycline
* 1964 – gentamicin
* 1964 – cefalotin, the first cephalosporin
* 1966 – doxycycline
* 1967 – carbenicillin
* 1967 – rifampicin
* 1967 – nalidixic acid, the first quinolone
* 1968 – clindamycin, the second lincosamide
* 1970 – cefalexin
* 1971 – cefazolin
* 1971 – pivampicillin
* 1971 – tinidazole
* 1972 – amoxicillin
* 1972 – cefradine
* 1972 – minocycline
* 1972 – pristinamycin
* 1973 – fosfomycin
* 1974 – talampicillin
* 1975 – tobramycin
* 1975 – bacampicillin
* 1975 – ticarcillin
* 1976 – amikacin
* 1977 – azlocillin
* 1977 – cefadroxil
* 1977 – cefamandole
* 1977 – cefoxitin
* 1977 – cefuroxime
* 1977 – mezlocillin
* 1977 – pivmecillinam
* 1979 – cefaclor
* 1980 – cefmetazole
* 1980 – cefotaxime
* 1980 – piperacillin
* 1981 – co-amoxiclav (amoxicillin/clavulanic acid)
* 1981 – cefoperazone
* 1981 – cefotiam
* 1981 – cefsulodin
* 1981 – latamoxef
* 1981 – netilmicin
* 1982 – ceftriaxone
* 1982 – micronomicin
* 1983 – cefmenoxime
* 1983 – ceftazidime
* 1983 – ceftizoxime
* 1983 – norfloxacin
* 1984 – cefonicid
* 1984 – cefotetan
* 1984 – temocillin
* 1985 – cefpiramide
* 1985 – imipenem/cilastatin, the first carbapenem
* 1985 – ofloxacin
* 1986 – mupirocin
* 1986 – aztreonam
* 1986 – cefoperazone/sulbactam
* 1986 – co-ticarclav (ticarcillin/clavulanic acid)
* 1987 – ampicillin/sulbactam
* 1987 – cefixime
* 1987 – roxithromycin
* 1987 – sultamicillin
* 1987 – ciprofloxacin, the first 2nd-gen fluoroquinolone
* 1987 – rifaximin, the first ansamycin
* 1988 – azithromycin
* 1988 – flomoxef
* 1988 – isepamycin
* 1988 – midecamycin
* 1988 – rifapentine
* 1988 – teicoplanin
* 1989 – cefpodoxime
* 1989 – enrofloxacin
* 1989 – lomefloxacin
* 1989 – moxifloxacin
* 1990 – arbekacin
* 1990 – cefodizime
* 1990 – clarithromycin
* 1991 – cefdinir
* 1992 – cefetamet
* 1992 – cefpirome
* 1992 – cefprozil
* 1992 – ceftibuten
* 1992 – fleroxacin
* 1992 – loracarbef
* 1992 – piperacillin/tazobactam
* 1992 – rufloxacin
* 1993 – brodimoprim
* 1993 – dirithromycin
* 1993 – levofloxacin
* 1993 – nadifloxacin
* 1993 – panipenem/betamipron
* 1993 – sparfloxacin
* 1994 – cefepime
* 1996 – meropenem
* 1999 – quinupristin/dalfopristin
* 2000 – linezolid, the first oxazolidinone
* 2001 – telithromycin, the first ketolide
* 2003 – daptomycin
* 2005 – tigecycline, the first glycylcycline
* 2005 – doripenem
* 2009 – telavancin, the first lipoglycopeptide
* 2010 – ceftaroline
* 2011 – fidaxomicin
* 2012 – bedaquiline
* 2013 – telavancin
* 2014 – tedizolid
* 2014 – dalbavancin
* 2014 – ceftolozane/tazobactam
* 2015 – ceftazidime/avibactam
* 2017 – meropenem/vaborbactam
* 2019 – imipenem/cilastatin/relebactam
* 2019 – cefiderocol