OpenLLM-France/wikimedia huggingface dataset:
# Canadine

(S)-Canadine, also known as (S)-tetrahydroberberine and xanthopuccine, is a benzylisoquinoline alkaloid (BIA), of the protoberberine structural subgroup, and is present in many plants from the family Papaveraceae, such as Corydalis yanhusuo and C. turtschaninovii.

## Biosynthesis

Metabolically, (S)-canadine is derived from (S)-reticuline, a pivotal intermediate in the biosynthesis of numerous BIA structural subgroups, through three enzymatic steps: 1) Berberine bridge enzyme to (S)-scoulerine; 2) (S)-scoulerine 9-O-methyltransferase to (S)-tetrahydrocolumbamine; and 3) (S)-canadine synthase/CYP719A21 to (S)-canadine.
(S)-Canadine is the immediate metabolic precursor of berberine, which is obtained through the action of the enzyme (S)-tetrahydroprotoberberine oxidase. It is also an intermediate in the complex biosynthesis of noscapine, which is likewise a benzylisoquinoline alkaloid, but of the phthalideisoquinoline structural subgroup.
(S)-Canadine, berberine, palmatine, and hydrastine are the major alkaloids present in goldenseal.

## Effects

A number of in vitro effects of (S)-canadine have been reported. It stimulates myogenesis and inhibits muscle protein degradation. (S)-Canadine blocks K(ATP) channels in dopamine neurons. (S)-Canadine has displayed antioxidant activity: though it lacked any demonstrable cytotoxic effect in three unique cell cultures, it was observed to possess antioxidant activity against free radical-induced oxidative injury. (S)-Canadine can block voltage-dependent calcium channels, but at a level significantly lower than that of verapamil.
# Thomas Watt (politician)
## Early life and education

Sir Thomas Watt KCMG (1857–1947) was a South African politician and cabinet minister.
# Producer

Producer(s), The Producer(s), or co-producer(s) may refer to:

## Occupations

* Producer (agriculture), a farm operator
* Producer, a stakeholder of economic production
* Film producer, supervises the making of films
** Executive producer, contributes to a film's budget and usually does not work on set
* Impresario, a producer or manager in the theatre and music industries
* Line producer, manager during daily operations of a film or TV series
* News producer, person who compiles all items of a news programme into a cohesive show
* Online producer, person who oversees the making of content for websites
* Radio producer, person who oversees the making of a radio show
* Record producer, person who manages sound recording
* Television producer, person who oversees all aspects of video production on a television program
* Theatrical producer, person who oversees the staging of theatre productions
* Video game producer, person in charge of overseeing development of a video game

## Film and television

* "The Producer", an episode of Gilligan's Island
* The Producers (1967 film), black comedy by Mel Brooks
* The Producers (2005 film), American musical comedy film based on 1967 film of the same name
* The Producers (TV series), 2015 South Korean television series
* "The Producers" (Smash), the 28th episode of the American television series Smash

## Music and performance

* The Producers (American band), a new wave and power pop band from Atlanta, Georgia
* The Producers (musical), a stage musical adapted by Mel Brooks and Thomas Meehan from the 1967 film
* The Producers (Trebol Clan album), a collaborative album by Trebol Clan, Dr. Joe & Mr. Frank
* The Trevor Horn Band (previously The Producers), an English supergroup

## Other uses

* Producer (biology) or autotroph, an organism that synthesizes energy-rich organic compounds
* The Producers, a pub in Grenfell Street, Adelaide, South Australia
# Vicente dela Serna

Vicente Low de la Serna (September 13, 1951 – September 1, 2018) was a Filipino lawyer, politician, and legislator. He was Cebu's 6th district's representative to the 8th Congress of the Philippines (1987–1992) and the governor of the province of Cebu, Philippines from 1992 until 1995.

## Early life

The son of Manuel H.P. de la Serna and Filipino-American Leonora A. Low, Vicente de la Serna was born in Butuan, Agusan del Norte on September 13, 1951. He and his wife Maria Dolores A. Bernad of Ozamiz, Misamis Occidental had three daughters and a son.
He got a bachelor's degree at Velez College and a law degree from University of San Carlos. On May 8, 1980, he was admitted to the bar and became a lawyer.

## Career

He was known as an anti-Marcos activist in Cebu in the 1980s and later appointed in charge of the Office of the Mayor of Mandaue City when Corazon Aquino became president after the 1986 EDSA revolution. In 1987, he ran for a legislative seat and won as member of the 8th Congress of the Republic representing Cebu's 6th district. He was chosen as the chairman of the House Committee on Civil, Political, and Human Rights. During his term in Congress, he advocated for social legislation and human rights. He appropriated his Countrywide Development Fund for Mandaue City Hospital, Mandaue Comprehensive High School, Mandaue Sports Complex, and Lapu-lapu City Sports Center.
In 1992, he was elected as governor of Cebu province succeeding Emilio Osmeña and served until 1995. It was during his term that the building of the Sugbo Cultural Center within the University of the Philippines Cebu Campus was started. Additionally, he was credited for the Provincial Board Ordinance 93-1 that identified properties owned by the provincial government but were occupied by about 5,000 informal settlers of Cebu City. Negotiations for a land swap deal between the provincial and city governments that would allow the residents to own the lot by paying a monthly amortization commenced and lasted for over two decades. By August 2018, the deal was finalized.
When he ran to be reelected as governor for a second term, he was defeated and succeeded by Pablo P. Garcia. During the administration of Joseph Estrada, Vicente de la Serna was appointed deputy executive secretary.

## Later years

In September 2017, he was diagnosed with lung cancer and underwent chemotherapy. He died succumbing to the disease in Sto. Niño Village in Barangay Banilad, Cebu City, at the age of 66 past midnight of September 1, 2018. Cebu Daily News editorial hailed him as man of the masses, and the Philippine News Agency noted his popularity among the common folks for "championing the causes of the poor and the marginalized."
# ASAD Purwakarta F.C.

Asli Sepakbola Anak Desa Purwakarta Football Club (simply known as ASAD Purwakarta; formerly known as ASAD 313 Jaya Perkasa) is a Indonesian football club based in Purwakarta Regency, West Java. They are currently competes in Liga 4 West Java Series 1.

## History

ASAD 313 Jaya Perkasa football school was founded in 2013 and is managed by Alwi Ahmad. In its development, this club has produced several famous Indonesian footballers, such as the top scorer of the 2023 SEA Games, Fajar Fathur Rahman and several other football players. Since its inception, this club has been under the auspices of the Purwakarta Regency Education Office and is facilitated by a dormitory located in the SKB Purwakarta area.

## Sponsors

* ENEF Apparel
* Polres Purwakarta
* APDESI Kabupaten Purwakarta
* APINDO
* Indomaret
* Sate Maranggi Haji Yetty

## Honours

* Liga 3 West Java Series 2
** (1):
# Park Avenue Tunnel

Park Avenue Tunnel may refer to:
* Park Avenue main line, railroad line with a tunnel section carrying Metro-North Railroad
** Park Avenue Tunnel (railroad), a railroad tunnel under Park Avenue in New York City
* Park Avenue Tunnel (roadway), a roadway tunnel under Park Avenue South in Murray Hill, in New York City
* Part of the IRT Lexington Avenue Line under Park Avenue, sometimes called the Park Avenue Tunnel
# Bohorodchany settlement hromada

Bohorodchany settlement hromada (Ukrainian: Богородчанська селищна громада) is a hromada in Ukraine, in Ivano-Frankivsk Raion of Ivano-Frankivsk Oblast. The administrative center is the rural settlement of Bohorodchany.

## Settlements

The hromada consists of 1 rural settlement (Bohorodchany) and 16 villages:
* Hlybivka
* Hlyboke
* Horokholyna
* Horokholyn Lis
* Hrabovets
* Dibrova
* Zhuraky
* Zaberezhzhia
* Ivanykivka
* Kopachivka
* Lastivtsi
* Pidhiria
* Pokhivka
* Sadzhava
* Starunia
* Khmelivka
# Jose Maria College

Jose Maria College Foundation, Inc. (JMCFI), or simply Jose Maria College (JMC), is a tertiary educational institution in Davao City, Philippines.

## Background

Jose Maria College was founded by pastor Apollo Quiboloy of the Kingdom of Jesus Christ church, naming the institution after his parents, José Quiboloy and María Carreon. The campus which broke ground in 2000 and opened two years later as the "Jose Maria Academy" is situated near Francisco Bangoy International Airport. It adopted its current name in 2003.

## Administration and admission

While its founder is affiliated with the Kingdom of Jesus Christ (KOJC), JMC is non-sectarian in administration and is open to admission to any students regardless of religious background. It offers both basic (kindergarten to senior high school) to tertiary education.
At the 2024 Senate hearings which tackled the alleged abuses of the KOJC and Quiboloy, the JMC were alleged to be promising KJC members scholarship in exchange for being full-time workers for KJC. The administration was also accused of withholding transcript of records from its ex-KJC students who left church.

## Sports

The Jose Maria College's varsity team are known as the JMC Kings. The JMC maintains a men's basketball team. They also have a women's volleyball team named the Lady Royals which has played in the 2023 National Invitationals of the Shakey's Super League.

## Presidents

* Apollo Quiboloy (2002–2021)
* Felix Chavez (2021–present)
# Playing with Fire (Robinson novel)

Playing with Fire is the 14th novel by Yorkshire-born, Canadian detective fiction writer Peter Robinson in the Inspector Banks series. It was published in 2004, and nominated for that year's Hammett Prize.

## Reception

Gary Curtis of the The Hamilton Spectator called it a "red-hot scorcher, a BritCrime epic with Peter Banks at his best." Oline H. Cogdill of the South Florida Sun Sentinel called the novel "crime fiction at its best" and opined that it "shows why Robinson's novel continue to be a pleasure." Al Hutchison of The Tampa Tribune opined that while the novel "may not quite match up to" In a Dry Season, the tenth novel in the series, as a "literary achievement", there is "no question Robinson is on a winning streak."
# Jaybrien Romano

Jaybrien Romano (born 13 December 2004) is a Dutch footballer who plays for Den Bosch and the Aruba national team.

## Club career

As a youth, Romano played for the academy of FC Twente. By 2019, he had joined the under-16 side of Sparta Rotterdam. In September of that year, he scored in a 1–5 league defeat to the under-16 side of AZ Alkmaar. Romano joined the academy of Stoke City in 2022. He went on to make one appearance for the club in the Under-18 Premier League, coming on as a substitute in a 2–1 victory over Newcastle United on 1 October.
Romano had joined the academy of National League club Aldershot Town by December 2023.

## International career

Romano represented Aruba in the 2022 CONCACAF U-20 Championship. He served as captain of the side for the tournament. He made his senior international debut on 11 September 2023 in a 2023–24 CONCACAF Nations League C match against the Cayman Islands. On the next matchday, he assisted on a goal by Rovien Ostiana against the U.S. Virgin Islands. Because of Romano's play, he was referred to as "Aruba's ace" by local media. The eventual 3–1 victory kept Aruba undefeated at the top of its group.

### International career statistics

    As of match played 16 November 2023.
Aruba national team :
| 2023 | 3 | 0 |
| Total | 3 | 0 |
# Charu Sharma

Charu Sharma is an Indian commentator, compere and quizmaster. He is the director of the Pro Kabaddi League.
He was the CEO of the Royal Challengers Bangalore cricket team for the 2008 Indian Premier League but was forced to leave due to the team's poor performance in the inaugural season. Even though the Royal Challengers officials said that Sharma resigned by himself, he contradicted them by saying that he was sacked by United Breweries Limited on behalf of Vijay Mallya, the team's owner.
Sharma was the stand-in auctioneer at the 2022 Indian Premier League auction, after Hugh Edmeades, the original auctioneer collapsed due to postural hypotension. Sharma conducted the auction after lunch on the first day, and continued till the last session on the next day, when Edmeades returned.

## Career

Charu Sharma is well known for his television presentations (especially on cricket) along with Mandira Bedi. He is also known as a quizmaster in television programmes and other event. He regularly hosts award shows, corporate events and contributes to teamwork and leadership seminar.
When The Economic Times talked to him about his Royal Challengers Bangalore dismissal he said: "I think I worked very hard for it, probably the hardest ever. Few matches were lost earlier and so heads were lost too. I like to believe that I was in the line of the steam of a pressure cooker that was waiting to release."

### Pro Kabaddi

The Pro Kabaddi League is a professional kabaddi league founded in 2014. It is an initiative of Mashal Sports, a company which was co-founded by Anand Mahindra and Sharma, who is also a director of Mashal Sports. Star India acquired a 74% stake in Mashal Sports, and now has control over the entire league as a majority owner of Mashal Sports. Mashal Sports has acquired the rights to organize the league for a period of 10 years from International Kabaddi Federation (IKF) with an option to renew it further.

### Coca-Cola Bahrain Premier League 2018

Charu Sharma was among the invitees to promote cricket in Bahrain and held the finals of Coca-Cola Bahrain Premier League Quiz 2018.
He is also a member of the Bangalore Political Action Committee (B.PAC).

### FUH Cast by Fakeeh University Hospital Dubai

FUHCast were thrilled to have the famous cricket commentator, Mr. Charu Sharma, as a special guest. Mr. Charu dives into the world of sports injuries, player health, and other medical-related topics. This episode at Fakeeh University Hospital Dubai packed with valuable insights for athletes, sports enthusiasts, and anyone interested in the intersection of sports and health.

## Personal life

Sharma is married to Anuja Sharma (née Mahindra). His wife is the sister of Indian industrialist Anand Mahindra.
His father was the educationist Mr N.C. Sharma, a former vice-principal of Mayo College, Ajmer.
# Jump in the Fire

"Jump in the Fire" is a song by American heavy metal band Metallica. It was released as the second and final single from their debut album, Kill 'Em All. The single was accompanied by fake live performances of "Phantom Lord" and "Seek & Destroy" which were alternate studio recordings with sounds of a crowd overdubbed in.
"Jump in the Fire" is one of Metallica's earliest recorded songs, having been included on Ron McGovney's '82 Garage demo, an unreleased recording. The original lyrics and content, which dealt with sex, were written by Dave Mustaine in his former band Panic at the age of 16. The original version that Mustaine introduced to Hetfield and Ulrich upon joining Metallica was raw. The three worked together on refining the song and the outcome is what is heard on the demo. However, much like the events surrounding "The Four Horsemen", new lyrics were written by James Hetfield upon Mustaine's departure from Metallica. The new lyrics revolve around people being damned to Hell and therefore "jumping in the fire." Lars Ulrich claims that they had written the song to sound like "Run to the Hills" by Iron Maiden, which was popular at the time. However, Mustaine has since denied this claim. Current live performances since 2004 are in D standard tuning, as opposed to the E standard tuning of earlier live performances.

## Commemoration

The single sleeve artwork depicts a red-skinned demonic creature basking in flames. This artwork copies the Demon off the cover of Graham Masterton's 1978 novel, The Devils of D-Day (Sphere, 1979 edition), painted by Les Edwards. In 2009, a collectible action figure of this character was released by MediCom Toy Inc. With an original retail price of $99.99, the approximately 12-inch (30.48 cm) tall figure is limited to 1,000 pieces and sold as an online exclusive.

## Personnel

Credits are adapted from Kill 'Em All liner notes.
* James Hetfield - vocals, rhythm guitar
* Kirk Hammett - lead guitar
* Cliff Burton - bass
* Lars Ulrich - drums

## Charts

| Chart (1990) | Peak position |
| New Zealand (Recorded Music NZ) | 30 |
# Wonderboys: The Secret Treasure of Naples

Wonderboys: The Secret Treasure of Naples (Italian: Uonderbois) is a 2024 Italian television series produced for Disney+. It was directed by Giorgio Romano and Andrea de Sica.

## Overview

Wonderboys: The Secret Treasure of Naples follows the adventures of five inseparable 12-year-old friends, known as the Wonderboys, who embark on a quest to find a legendary treasure hidden in the underground of Naples. Their journey begins when their homes are threatened with eviction by the Old Hag, who plans to sell their apartments in exchange for a Maradona figurine. The figurine is stolen by their idol, Tonino Wonderboy, who becomes the new Munaciello of Naples. The Wonderboys must navigate the city's underground, facing various challenges and dangers, as they search for the mysterious treasure.
The series blends elements of drama, adventure, and family themes, capturing the essence of friendship and bravery as the Wonderboys work together to save their homes and uncover the secrets of Naples.

## Production

The filming of Wonderboys: The Secret Treasure of Naples took place in Naples between December 2022 and March 2023.

## Release
### Streaming

All episodes of the series were released on Disney+ on 6 December 2024.

### Soundtrack

The soundtrack of the series was released on December 18, 2024 by Walt Disney Records, Andrea Farri composed the original music.
# International School Ho Chi Minh City - American Academy

The International School Ho Chi Minh City - American Academy (ISHCMC - American Academy) is an international school for middle and high school children aged 11 to 18 years old in Ho Chi Minh City, Vietnam. ISHCMC - American Academy is one of three schools in Vietnam under the school's group Cognita, along with the International School Ho Chi Minh City and International School Saigon Pearl.

## American Curriculum

ISHCMC - American Academy delivers a full American curriculum under the American Education Reaches Out (AERO) framework, which is aligned closely with U.S. national standards across math, science, English, and social studies. All students from Grades 6 to 12 take the U.S. Measures of Academic Progress (MAP) standardized assessments in English, Reading, and Math twice a year.

### English Language

ISHCMC - American Academy teaches in the English curriculum and has an English as an Additional Language (EAL) Program for students whose English is not their first language. The EAL program is based on the WIDA framework and assessments, which progresses students through 6 stages of the language acquisition process until they reach a proficiency level equivalent to that of a native speaker.

## University Preparation
### Syracuse University Project Advance

ISHCMC - American Academy is the only school in Vietnam to offer early university credit through the Syracuse University Project Advance (SUPA). Through this partnership, ISHCMC - American Academy students can take university-level courses that use the same syllabi, materials, textbooks, assignments and assessments as those offered at Syracuse University. Successful completion of SUPA courses and examinations earns ISHCMC - American Academy students early university credit while still in high school, saving both time and money in their tertiary education. SUPA students at ISHCMC - American Academy also graduate with two transcripts: an American high school diploma and a SUPA transcript.

### University Counseling Program

ISHCMC - American Academy offers a University Counseling Program where a professional counselor regularly meets with students to assist in achieving their university goals. The counselor coordinates university tours, helps with university selection and applications, and provides information on financial aid. In their final year, 12th grade students participate in a week-long University Boot Camp focused on university applications. The program is supported by an on-site University Counseling Suite, equipped with resources and tools for the admissions process.

### Advanced Placement Program

ISHCMC – American Academy students can take university-level courses through the Advanced Placement (AP) Program. More than 90% of the four-year colleges and universities in the U.S. have an AP policy that grants credit, placement, or both for qualifying AP Exam scores to incoming students.
# Lord Thomas Cecil

Lord Thomas Cecil (1797–1873) was a British peer and member of Parliament for Stamford from 1818 to 1832.
Cecil was the youngest of the three sons of Henry Cecil, 1st Marquess of Exeter, by his second wife Sarah. He was educated at Eton and St John's College, Cambridge, graduating in 1815.
He married, on 8 August 1838, Lady Sophia Lennox, daughter of Charles Lennox, 4th Duke of Richmond, but they had no children. He died on 29 November 1873.
# Neapolitan wafer

Neapolitan wafers (also called gaufrettes in some countries, though this term can refer to other foods) are wafer and chocolate-cream sandwich biscuits, first made by the Austrian company Manner in 1898.
Using hazelnuts imported from the area of Naples, Italy, to make the hazelnut-flavoured chocolate cream filling, they have five wafers and four layers of cream in their 49 millimetres (1.9 in) × 17 millimetres (0.67 in) × 17 millimetres (0.67 in) biscuit size. The basic recipe has remained unchanged into the 21st century.
Manner still sells the biscuits in blocks of ten. Many other companies have copied the idea, most often coating the bar in chocolate.
They were mass-produced in the USSR and the Eastern Bloc for their cheap production cost, long shelf-life and simple production method. Up to this day they are a popular treat in Russia and post-soviet countries, especially popular among seniors.