# 2021 FINA World Swimming Championships (25 m) – Mixed 4 × 50 metre freestyle relay

The Mixed 4 × 50 metre freestyle relay competition of the 2021 FINA World Swimming Championships (25 m) was held on 17 December 2021.

## Records

Prior to the competition, the existing world and championship records were as follows.
| World record | United States (USA) | 1:27.89 | Hangzhou, China | 12 December 2018 |
| Competition record | United States (USA) | 1:27.89 | Hangzhou, China | 12 December 2018 |

## Results
### Heats

The heats were started at 10:58.
| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| 1 | 4 | 4 | Russian Swimming Federation | Andrey Minakov (21.04) Daniil Markov (21.30) Arina Surkova (23.50) Rozaliya Nasretdinova (24.00) | 1:29.84 | Q |
| 2 | 4 | 5 | Italy | Marco Orsi (21.70) Leonardo Deplano (20.91) Silvia Di Pietro (23.78) Costanza Cocconcelli (24.05) | 1:30.44 | Q |
| 3 | 2 | 4 | Netherlands | Jesse Puts (21.49) Kenzo Simons (21.20) Kira Toussaint (23.89) Ranomi Kromowidjojo (23.92) | 1:30.50 | Q |
| 4 | 3 | 5 | United States | Zach Apple (21.76) Hunter Tapp (21.73) Kate Douglass (23.59) Torri Huske (24.23) | 1:31.31 | Q |
| 5 | 1 | 4 | Hong Kong | Ng Cheuk Yin (22.26) Ian Ho (21.01) Siobhán Haughey (23.69) Tam Hoi Lam (24.37) | 1:31.33 | Q, NR |
| 6 | 3 | 4 | France | Maxime Grousset (21.48) Thomas Piron (21.69) Béryl Gastaldello (24.03) Analia Pigrée (24.30) | 1:31.50 | Q |
| 7 | 3 | 2 | Canada | Joshua Liendo (21.00) Yuri Kisil (21.22) Rebecca Smith (25.01) Katerine Savard (24.40) | 1:31.63 | Q |
| 8 | 4 | 1 | Switzerland | Thomas Hallock (22.14) Roman Mityukov (21.94) Nina Kost (24.67) Alexandra Touretski (24.38) | 1:33.13 | Q, NR |
| 9 | 2 | 5 | Turkey | Emre Sakçı (21.47) Baturalp Ünlü (21.73) Ekaterina Avramova (25.06) Selen Özbilen (25.89) | 1:34.15 | |
| 10 | 4 | 3 | Slovakia | Matej Duša (21.75) Ádám Halás (22.32) Lillian Slušná (25.58) Tamara Potocká (25.14) | 1:34.79 | NR |
| 11 | 4 | 9 | Luxembourg | Julien Henx (22.45) Max Mannes (22.43) Julie Meynen (25.15) Monique Olivier (25.57) | 1:35.60 | NR |
| 12 | 3 | 1 | Bahamas | Lamar Taylor (22.10) Izaak Bastian (22.27) Lillian Higgs (26.03) Joanna Evans (26.03) | 1:36.43 | |
| 13 | 1 | 6 | Thailand | Supha Sangaworawong (22.91) Tonnam Kanteemool (22.91) Kornkarnjana Sapianchai (25.98) Jenjira Srisaard (24.78) | 1:36.58 | NR |
| 14 | 2 | 7 | Jamaica | Sidrell Williams (23.39) Alia Atkinson (25.04) Keanan Dols (23.61) Zaneta Alvaranga (25.78) | 1:37.82 | |
| 15 | 3 | 6 | Dominican Republic | Josué Domínguez (22.92) Krystal Lara (25.85) Elizabeth Jiménez (26.89) Denzel González (22.96) | 1:38.62 | |
| 16 | 3 | 8 | Aruba | Elisabeth Timmer (25.77) Bransly Dirksz (24.98) Chloe Farro (26.47) Mikel Schreuders (21.64) | 1:38.86 | |
| 17 | 2 | 6 | Andorra | Tomàs Lomero (23.10) Patrick Pelegrina (23.27) Mònica Ramírez (26.72) Nàdia Tudó (26.81) | 1:39.90 | NR |
| 18 | 3 | 9 | Antigua and Barbuda | Stefano Mitchell (22.69 NR) Jadon Wuilliez (22.15) Samantha Roberts (26.77) Bianca Mitchell (28.30) | 1:39.91 | |
| 19 | 3 | 3 | Armenia | Artur Barseghyan (22.32) Vladimir Mamikonyan (23.17) Varsenik Manucharyan (27.13) Ani Poghosyan (27.38) | 1:40.00 | |
| 20 | 2 | 9 | Cayman Islands | Richard Allison (23.75) Liam Henry (24.16) Lauren Hew (26.24) Alison Jackson (25.93) | 1:40.08 | |
| 21 | 1 | 7 | Senegal | Steven Aimable (23.02) Adama Niane (22.89) Jeanne Boutbien (27.49) Oumy Diop (26.80) | 1:40.20 | |
| 22 | 2 | 3 | Albania | Kledi Kadiu (23.20) Nikol Merizaj (25.68) Katie Rock (28.10) Dalvi Elezi (23.72) | 1:40.70 | |
| 23 | 4 | 7 | Uganda | Tendo Mukalazi (23.78) Jesse Ssengonzi (23.44) Avice Meya (28.50) Kirabo Namutebi (25.82) | 1:41.54 | |
| 24 | 2 | 0 | Saint Lucia | Jayhan Odlum-Smith (23.10) Naima Hazell (27.29) Terrel Monplaisir (24.45) Mikaili Charlemagne (26.77) | 1:41.61 | |
| 25 | 1 | 3 | Faroe Islands | Bartal Erlingsson Eidesgaard (23.86) Johan Nónskarð Dam (25.14) Elisabeth Erlendsdóttir (26.62) Alisa Bech Vestergård (27.03) | 1:42.65 | |
| 26 | 3 | 0 | Mongolia | Batbayaryn Enkhtamir (24.36) Batmönkhiin Jürmed (24.83) Batbayaryn Enkhkhüslen (26.58) Khuyagbaataryn Enkhzul (27.16) | 1:42.93 | |
| 27 | 1 | 1 | Seychelles | Mathieu Bachmann (23.85) Aaliyah Palestrini (27.50) Khema Elizabeth (28.34) Simon Bachmann (23.83) | 1:43.52 | |
| 28 | 2 | 1 | Mauritius | Gregory Anodin (23.57) Jonathan Chung Yee (25.81) Kimberley Kok (27.42) Tessa Ip Hen Cheung (26.95) | 1:43.75 | |
| 29 | 1 | 0 | Angola | Salvador Gordo (24.45) Lia Lima (28.99) Catarina Sousa (27.06) Henrique Mascarenhas (23.43) | 1:43.93 | |
| 30 | 1 | 9 | Malawi | Filipe Gomes (23.67) Muhammad Moosa (28.42) Jessica Makwenda (28.94) Ammara Pinto (28.21) | 1:49.24 | |
| 31 | 4 | 2 | Northern Mariana Islands | Jinnosuke Suzuki (25.06) Juhn Tenorio (23.81) Asaka Litulumar (30.08) Shoko Litulumar (31.14) | 1:50.09 | |
| 32 | 1 | 8 | Guam | Mineri Gomez (29.90) Mark Imazu (25.97) Keana Santos (29.58) Israel Poppe (24.66) | 1:50.11 | |
| 33 | 2 | 2 | Maldives | Mohamed Aan Hussain (25.07) Aishath Sausan (29.80) Hamna Ahmed (30.28) Ali Imaan (25.61) | 1:50.76 | |
| | 1 | 2 | Turks and Caicos Islands | | DNS | |
| | 1 | 5 | Peru | | DNS | |
| | 2 | 8 | Bosnia and Herzegovina | | DNS | |
| | 3 | 7 | Nigeria | | DNS | |
| | 4 | 0 | Singapore | | DNS | |
| | 4 | 6 | Tanzania | | DNS | |
| | 4 | 8 | Cape Verde | | DNS | |

### Final

The final was held at 19:49.
| Rank | Lane | Nation | Swimmers | Time | Notes |
| | 1 | Canada | Joshua Liendo (20.94) Yuri Kisil (20.99) Kayla Sanchez (23.51) Maggie Mac Neil (23.11) | 1:28.55 | NR |
| | 3 | Netherlands | Jesse Puts (21.33) Thom de Boer (20.35) Ranomi Kromowidjojo (22.97) Kira Toussaint (23.96) | 1:28.61 | |
| | 4 | Russian Swimming Federation | Vladimir Morozov (21.17) Andrey Minakov (20.95) Maria Kameneva (23.17) Arina Surkova (23.68) | 1:28.97 | |
| 4 | 6 | United States | Ryan Held (20.86) Zach Apple (21.31) Kate Douglass (23.70) Abbey Weitzeil (23.17) | 1:29.04 | |
| 5 | 5 | Italy | Lorenzo Zazzeri (21.13) Alessandro Miressi (21.18) Silvia Di Pietro (23.53) Costanza Cocconcelli (24.18) | 1:30.02 | |
| 6 | 7 | France | Maxime Grousset (21.17) Thomas Piron (21.43) Marie Wattel (23.88) Béryl Gastaldello (23.58) | 1:30.06 | |
| 7 | 2 | Hong Kong | Ng Cheuk Yin (22.29) Ian Ho (20.61) Siobhán Haughey (23.42) Tam Hoi Lam (24.11) | 1:30.43 | NR |
| 8 | 8 | Switzerland | Roman Mityukov (22.13) Thomas Hallock (21.37) Maria Ugolkova (24.13) Alexandra Touretski (24.33) | 1:31.96 | NR |