# 2022 Internationaux de Tennis de Blois – Singles

Pedro Sousa was the defending champion but chose not to defend his title.
Alexandre Müller won the title after defeating Nikola Milojević 7–6$^{(7–3)}$, 6–1 in the final.

## Seeds

* Zdeněk Kolář (first round)
* Corentin Moutet (first round)
* Camilo Ugo Carabelli (second round)
* Pedro Cachin (first round)
* Vít Kopřiva (semifinals)
* Dennis Novak (second round)
* Nikola Milojević (final)
* Nino Serdarušić (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 7 | Nikola Milojević | 7$^7$ | 6 | | | | |
| 5 | Vít Kopřiva | 6$^1$ | 2 | | | | |
| 5 | Vít Kopřiva | 6$^1$ | 2 | 7 | Nikola Milojević | 6$^3$ | 1 |
| | | | | | Alexandre Müller | 7$^7$ | 6 |
| | Alexandre Müller | 7$^7$ | 6 | | Alexandre Müller | 7$^7$ | 6 |
| Q | Luca Van Assche | 6$^4$ | 3 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | Z Kolař | 2 | 4 | | | | | | | | | | | | | | | |
| Q | E Karlovskiy | 6 | 6 | | Q | E Karlovskiy | 2 | 7$^7$ | 6 | | | | | | | | | |
| | M Arnaldi | 6 | 6 | | | M Arnaldi | 6 | 6$^4$ | 4 | | | | | | | | | |
| | E Couacaud | 4 | 2 | | | | | | | Q | E Karlovskiy | 1 | 6 | 2 | | | | |
| | T Skatov | 6 | 7$^7$ | | | | | | | 7 | N Milojević | 6 | 4 | 6 | | | | |
| | F Díaz Acosta | 4 | 6$^2$ | | | T Skatov | 6 | 4 | 4 | | | | | | | | | |
| | G Barrère | 1 | 0 | | 7 | N Milojević | 4 | 6 | 6 | | | | | | | | | |
| 7 | N Milojević | 6 | 6 | | | | | | | | | | | | 7 | N Milojević | 7$^7$ | 6 |
| 4 | P Cachin | 4 | 2 | | | | | | | | | | | | 5 | V Kopřiva | 6$^1$ | 2 |
| | M Marterer | 6 | 6 | | | M Marterer | 6 | 7$^7$ | | | | | | | | | | |
| Q | A Rybakov | 6 | 7 | | Q | A Rybakov | 3 | 6$^4$ | | | | | | | | | | |
| | Z Piros | 3 | 5 | | | | | | | | M Marterer | 5 | 3 | | | | | |
| WC | A Fils | 2 | 6 | 2 | | | | | | 5 | V Kopřiva | 7 | 6 | | | | | |
| | Em Nava | 6 | 3 | 6 | | Em Nava | 1 | 4 | | | | | | | | | | |
| | L Giustino | 6 | 4 | 6$^5$ | 5 | V Kopřiva | 6 | 6 | | | | | | | | | | |
| 5 | V Kopřiva | 2 | 6 | 7$^7$ | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | D Novak | 6 | 7$^7$ | | | | | | | | | | | | | | |
| WC | T Atmane | 4 | 6$^4$ | | 6 | D Novak | 2 | 4 | | | | | | | | | |
| Q | S Mochizuki | 6 | 4 | 2 | Alt | GA Olivieri | 6 | 6 | | | | | | | | | |
| Alt | GA Olivieri | 3 | 6 | 6 | | | | | | Alt | GA Olivieri | 1 | 1 | | | | |
| | A Collarini | 7$^7$ | 6$^7$ | 4 | | | | | | | A Müller | 6 | 6 | | | | |
| | A Müller | 6$^4$ | 7$^9$ | 6 | | A Müller | 6$^5$ | 6 | 6 | | | | | | | | |
| Q | G Décamps | 2 | 3 | | 3 | C Ugo Carabelli | 7$^7$ | 4 | 1 | | | | | | | | |
| 3 | C Ugo Carabelli | 6 | 6 | | | | | | | | | | | | A Müller | 7$^7$ | 6 |
| 8 | N Serdarušić | 6 | 7$^7$ | | | | | | | | | | | Q | L Van Assche | 6$^4$ | 3 |
| Alt | G Lama | 3 | 6$^4$ | | 8 | N Serdarušić | 3 | 2 | | | | | | | | | |
| | C-M Stebe | 2 | 3 | | Q | N Sánchez Izquierdo | 6 | 6 | | | | | | | | | |
| Q | N Sánchez Izquierdo | 6 | 6 | | | | | | | Q | N Sánchez Izquierdo | 4 | 6$^4$ | | | | |
| | A Shevchenko | 6$^5$ | 2 | | | | | | | Q | L Van Assche | 6 | 7$^7$ | | | | |
| Q | L Van Assche | 7$^7$ | 6 | | Q | L Van Assche | 2 | 6 | 6 | | | | | | | | |
| | E Furness | 6 | 0 | 6 | | E Furness | 6 | 4 | 3 | | | | | | | | |
| 2/WC | C Moutet | 4 | 6 | 1 | | | | | | | | | | | | | |