# 2022 U.S. Open Cup

The 2022 Lamar Hunt U.S. Open Cup was the 107th edition of the U.S. Open Cup, a knockout cup competition in American soccer. After the 2020 and 2021 competitions were suspended and ultimately canceled due to the COVID-19 pandemic, the United States Soccer Federation announced that the 2022 edition would run from March to mid-September of that year. The 2022 field features 103 clubs, 71 of them fully professional—both modern-era records.
On December 22, 2021, U.S. Soccer announced the final format for the 2022 tournament, with two major changes from prior editions. First, all eligible Division II and Division III professional teams entered the second round. Second, Major League Soccer had their teams entry staggered: Seventeen MLS teams entered the Third Round, and the remaining eight teams (the four playing in the 2022 CONCACAF Champions League, and the next highest two teams in both the Eastern and Western Conferences) entered the Round of 32.
For the first time since 2017, multiple leagues from the same division competed in the Open Cup. USL League One, of Division III, competed alongside teams from MLS Next Pro and the National Independent Soccer Association (NISA). NISA was set to make its Open Cup debut in 2020, before that tournament was canceled; MLS Next Pro was established in 2021, and while primarily a developmental league for MLS teams, its independent clubs are eligible for the Open Cup.
Atlanta United FC was the defending champion, when Atlanta won the 2019 tournament, but was eliminated in the Round of 32 by Nashville SC.
Orlando City SC won their first Open Cup title, defeating Sacramento Republic FC 3–0 in the final.

## Schedule

Schedule for 2022 Lamar Hunt U.S. Open Cup :
| Round | Draw date | Match day | Entrants | Teams entered to date |
| First round | February 2, 2022 | March 22–23, 2022 | 11 teams from local qualification 2021 National Amateur Cup Champion 10 NPSL teams 10 USL2 teams | 32 |
| Second round | February 11, 2022 | April 5–7, 2022 | 16 winners from First Round 23 USL Championship teams 2 MLS Next Pro teams 10 NISA teams 11 USL League One teams | 78 |
| Third round | April 8, 2022 | April 19–20, 2022 | 31 winners from Second Round 17 MLS teams | 95 |
| Round of 32 | April 21, 2022 | May 10–11, 2022 | 24 winners from Third Round 8 MLS teams | 103 |
| Round of 16 | May 12, 2022 | May 24–25, 2022 | 16 winners from Round of 32 | 103 |
| Quarterfinals | May 12, 2022 | June 21–22, 2022 | 8 winners from Round of 16 | 103 |
| Semifinals | June 23, 2022 | July 27, 2022 | 4 winners from Quarterfinals | 103 |
| Final | June 23, 2022 | September 7, 2022 | 2 winners from Semifinals | 103 |

## Teams

Pro teams that are majority-owned or controlled by higher division professional clubs are barred from entering the competition. For this edition of the tournament, there are 21 such teams: Atlanta United 2 (USLC), LA Galaxy II (USLC), Loudoun United FC (USLC), New York Red Bulls II (USLC), and 17 out of 19 MLS Next Pro teams. The two MLS Next Pro teams entering are Rochester New York FC (independent club) and St. Louis City SC 2 (the club's senior team does not debut until the 2023 season).

### Table

| Enter in First Round | Enter in First Round | Enter in Second Round | Enter in Second Round | Enter in Third Round | Enter in Round of 32 |
| Open Division | Open Division | Division III | Division II | Division I | Division I |
| USCS/USASA/USSSA/ANFEEU 12 teams | NPSL/USL2 20 teams | MLS Next Pro/NISA/USL1 23 teams | USL Championship 23 teams | MLS 25 teams | MLS 25 teams |
| National Amateur Cup Lansdowne Yonkers FC (EPSL) Local Qualifiers Azteca FC (Colo SL) Brockton FC United (BSSL) City Soccer FC (NSL) Contra Costa FC (NPSL) D'Feeters Kicks Soccer Club (RL) Escondido FC (UPSL) Lynchburg FC (UPSL) Northern Virginia FC (EPSL) Orlando FC Wolves (NSL) Oyster Bay United FC (UPSL) San Fernando Valley FC (UPSL) | NPSL Cleveland SC Denton Diablos FC Georgia Revolution FC Hartford City FC Las Vegas Legends Miami United FC Minneapolis City SC FC Motown $ Southern States Soccer Club Tulsa Athletic USL2 Chicago FC United Des Moines Menace North Carolina Fusion U23 Ocean City Nor'easters Park City Red Wolves SC Portland Timbers U23s South Carolina United The Villages SC West Chester United SC Western Mass Pioneers | MLS Next Pro Rochester New York FC St. Louis City SC 2 NISA Albion San Diego Bay Cities FC California United Strikers FC Chattanooga FC Flower City Union Los Angeles Force Maryland Bobcats FC Michigan Stars FC AC Syracuse Pulse Valley United FC USL1 Central Valley Fuego FC Charlotte Independence Chattanooga Red Wolves SC Forward Madison FC Greenville Triumph SC North Carolina FC Northern Colorado Hailstorm FC Richmond Kickers South Georgia Tormenta FC FC Tucson Union Omaha $ | Birmingham Legion FC Charleston Battery Colorado Springs Switchbacks FC Detroit City FC El Paso Locomotive FC Hartford Athletic Indy Eleven Las Vegas Lights FC Louisville City FC Memphis 901 FC Miami FC Monterey Bay FC New Mexico United Oakland Roots SC Orange County SC Phoenix Rising FC Pittsburgh Riverhounds SC Rio Grande Valley FC Sacramento Republic FC $$ San Antonio FC San Diego Loyal SC Tampa Bay Rowdies FC Tulsa | Atlanta United FC Austin FC Charlotte FC Chicago Fire FC FC Cincinnati Columbus Crew D.C. United FC Dallas Houston Dynamo FC Inter Miami CF Los Angeles FC LA Galaxy Minnesota United FC New York Red Bulls Orlando City SC $$$ Real Salt Lake San Jose Earthquakes | Colorado Rapids Nashville SC New England Revolution New York City FC Philadelphia Union Portland Timbers Seattle Sounders FC Sporting Kansas City |
* Bold denotes team is still active in the tournament.
* $: Winner of $25,000 bonus for advancing the furthest in the competition from their respective divisions.
* $$: Winner of $100,000 for being the runner-up in the competition.
* $$$: Winner of $300,000 for winning the competition.

### Map

* MLS
* USLC
* Division 3 (MLS Next Pro/NISA/USL1)
* Open Division (NPSL/USL2)
* Local Qualifiers & National Amateur Cup Champion
* Multiple Teams
Metro areas with multiple teams: Atlanta: Atlanta United FC (MLS), Georgia Revolution FC (NPSL) Boston: New England Revolution (MLS), Brockton FC United (Local) Charlotte: Charlotte FC (MLS), Charlotte Independence (USL1) Chattanooga: Chattanooga FC (NISA), Chattanooga Red Wolves SC (USL1) Chicago: Chicago Fire FC (MLS), Chicago FC United (USL2) Dallas: FC Dallas (MLS), Denton Diablos FC (NPSL), D'Feeters Kicks Soccer Club (Local) Denver: Colorado Rapids (MLS), Azteca FC (Local) Detroit: Detroit City FC (USLC), Michigan Stars FC (NISA) Hartford: Hartford Athletic (USLC), Hartford City FC (NPSL) Las Vegas: Las Vegas Lights FC (USLC), Las Vegas Legends (NPSL) Los Angeles: Los Angeles FC (MLS), LA Galaxy (MLS), Orange County SC (USLC), California United Strikers FC (NISA), Los Angeles Force (NISA), San Fernando Valley FC (Local) Miami: Inter Miami CF (MLS), Miami FC (USLC), Miami United FC (NPSL) Minneapolis/St. Paul: Minnesota United FC (MLS), Minneapolis City SC (NPSL) New York City: New York City FC (MLS), New York Red Bulls (MLS), FC Motown (NPSL), Lansdowne Yonkers FC (Local), Oyster Bay United FC (Local) Orlando: Orlando City SC (MLS), Orlando FC Wolves (Local) Philadelphia: Philadelphia Union (MLS), West Chester United SC (USL2) Phoenix: Phoenix Rising FC (USLC), Valley United FC (NISA) Rochester: Rochester New York FC (MLS Next Pro), Flower City Union (NISA) San Diego: San Diego Loyal SC (USLC), Albion San Diego (NISA) San Francisco Bay Area: San Jose Earthquakes (MLS), Oakland Roots SC (USLC), Bay Cities FC (NISA), Contra Costa FC (Local) Tulsa: FC Tulsa (USLC), Tulsa Athletic (NPSL)

### Number of teams by state

A total of 35 states and the District of Columbia are represented by clubs in the U.S. Open Cup this year.
| | States | Number | Teams |
| 1 | California | 16 | Albion San Diego, Bay Cities FC, California United Strikers FC, Central Valley Fuego FC, Contra Costa FC, Escondido FC, LA Galaxy, Los Angeles FC, Los Angeles Force, Monterey Bay FC, Oakland Roots SC, Orange County SC, Sacramento Republic FC, San Diego Loyal SC, San Fernando Valley FC, San Jose Earthquakes |
| 2 | Florida | 8 | City Soccer FC, Inter Miami CF, Miami FC, Miami United FC, Orlando City SC, Orlando FC Wolves, Tampa Bay Rowdies, The Villages SC |
| 2 | Texas | 8 | Austin FC, FC Dallas, Denton Diablos FC, D'Feeters Kicks SC, El Paso Locomotive FC, Houston Dynamo, Rio Grande Valley FC, San Antonio FC |
| 4 | New York | 6 | AC Syracuse Pulse, Flower City Union, Lansdowne Yonkers FC, New York City FC, Oyster Bay FC United, Rochester New York FC |
| 5 | Colorado | 4 | Azteca FC, Colorado Rapids, Colorado Springs Switchbacks FC, Northern Colorado Hailstorm FC |
| 5 | North Carolina | 4 | Charlotte FC, Charlotte Independence, North Carolina FC, North Carolina Fusion U23 |
| 5 | Tennessee | 4 | Chattanooga FC, Chattanooga Red Wolves SC, Memphis 901 FC, Nashville SC |
| 8 | Arizona | 3 | Phoenix Rising FC, FC Tucson, Valley United FC |
| 8 | Georgia | 3 | Atlanta United FC, Georgia Revolution FC, South Georgia Tormenta FC |
| 8 | Massachusetts | 3 | Brockton FC United, New England Revolution, Western Mass Pioneers |
| 8 | New Jersey | 3 | FC Motown, New York Red Bulls, Ocean City Nor'easters |
| 8 | Ohio | 3 | FC Cincinnati, Cleveland SC, Columbus Crew |
| 8 | Pennsylvania | 3 | Philadelphia Union, Pittsburgh Riverhounds SC, West Chester United SC |
| 8 | South Carolina | 3 | Charleston Battery, Greenville Triumph SC, SC United Bantams |
| 8 | Virginia | 3 | Lynchburg FC, Northern Virginia FC, Richmond Kickers |
| 16 | Connecticut | 2 | Hartford Athletic, Hartford City FC |
| 16 | Illinois | 2 | Chicago FC United, Chicago Fire FC |
| 16 | Michigan | 2 | Detroit City FC, Michigan Stars FC |
| 16 | Minnesota | 2 | Minnesota United FC, Minneapolis City SC |
| 16 | Oklahoma | 2 | FC Tulsa, Tulsa Athletic |
| 16 | Oregon | 2 | Portland Timbers, Portland Timbers U23s |
| 16 | Nevada | 2 | Las Vegas Lights FC, Las Vegas Legends |
| 16 | Utah | 2 | Park City Red Wolves SC, Real Salt Lake |
| 24 | Alabama | 1 | Birmingham Legion FC |
| 24 | District of Columbia | 1 | D.C. United |
| 24 | Indiana | 1 | Indy Eleven |
| 24 | Iowa | 1 | Des Moines Menace |
| 24 | Kansas | 1 | Sporting Kansas City |
| 24 | Kentucky | 1 | Louisville City FC |
| 24 | Maryland | 1 | Maryland Bobcats FC |
| 24 | Mississippi | 1 | Southern States Soccer Club |
| 24 | Missouri | 1 | St. Louis City SC 2 |
| 24 | Nebraska | 1 | Union Omaha |
| 24 | New Mexico | 1 | New Mexico United |
| 24 | Washington | 1 | Seattle Sounders FC |
| 24 | Wisconsin | 1 | Forward Madison FC |
States without a team in the Open Cup: Alaska, Arkansas, Delaware, Hawaii, Idaho, Louisiana, Maine, Montana, New Hampshire, North Dakota, Rhode Island, South Dakota, Vermont, West Virginia, and Wyoming.

### Open Cup debuts

31 teams played in their first Open Cup tournament in 2022.
* MLS: Austin FC, Charlotte FC, Inter Miami CF
* USLC: Monterey Bay FC, Oakland Roots SC, Rio Grande Valley FC Toros, San Diego Loyal SC
* MLS Next Pro: St. Louis City SC 2
* NISA: Albion San Diego, AC Syracuse Pulse, Bay Cities FC, California United Strikers FC, Flower City Union, Los Angeles Force, Maryland Bobcats FC, Michigan Stars FC, Valley United FC
* USL1: Central Valley Fuego FC, Northern Colorado Hailstorm FC, Union Omaha
* NPSL: Cleveland SC, Denton Diablos FC, Southern States Soccer Club, Las Vegas Legends
* USL2: Minneapolis City SC, Park City Red Wolves SC
* UPSL: Escondido FC, Lynchburg FC, Oyster Bay United FC, San Fernando Valley FC
* Other Open Division: Brockton FC United, D'Feeters Kicks SC
Due to their league's scheduling, Northern Colorado Hailstorm FC's 1-0 victory in the Second Round was the first time in the U.S. Open Cup's modern era that a club recorded their first-ever competitive match, goal, and victory in the Open Cup.

## Format
### Draws

* No team who was playing their first Open Cup match was paired with another team also playing their first Open Cup match. An exception was made if there were no other teams that were geographically close in order to prevent excess travel.
* Random pairings were done in cases where three or more teams were from the same general area.
* In cases where a geographical fit didn't exist, a random selection occurred.
* Pairings between clubs and their parent clubs, clubs with shared ownership, or other clubs using the same technical resources was avoided in geographic selections and random pairings until the final. For 2022, these pairings included: Los Angeles FC (MLS) and Las Vegas Lights (USLC), Portland Timbers (MLS) and Portland Timbers U23 (USL2), Chattanooga Red Wolves SC (USL1) and Park City Red Wolves SC (USL2).

### Matches

* Single-game-knockout format with two 45-minute halves and stoppage time.
* Tied matches are sent to two 15-minute extra time halves with stoppage time.
* Matches tied after extra time will be settled with a penalty shootout.
* Home teams are determined by a random selection among teams that apply to host. Teams that meet minimum tournament standards will be given priority over others in their pairing.
* Five substitutions during regulation time over three substitution windows and halftime.
* One extra substitution added during extra time. This substitution can be made at the end of regulation, over an additional substitution window, or at extra time halftime.
* Up to two extra substitutions over two extra substitution windows will be available in the case of a concussion. If a team uses this concussion substitution, the opposing team gains an additional substitution and substitution window.

## First and Second rounds

In the First round, teams (local, National Amateur Cup, NPSL, & USL2) were paired in a geographical manner, pitting teams closer together against each other. Once the First round pairings were made those pairings were matched with a Division II (USLC) or a Division III (MLS Next Pro, NISA, or USL1) team in a geographical manner for the Second round. Division II & III teams that remained unmatched were matched together, again geographically, avoiding any same-division matching (e.g., no II vs II or III vs III).
The complete draw for the First round, including match dates and times, was announced on February 2, 2022. Draws for the Second round were announced on February 11; match dates and times were announced on February 28.

### Bracket

| First round March 22–23 | First round March 22–23 | First round March 22–23 | Second round April 5–7 | Second round April 5–7 | Second round April 5–7 |
| NPSL | FC Motown | 1 | NISA | AC Syracuse Pulse | 0 |
| USL2 | West Chester United SC | 0 | NPSL | FC Motown | 1* |
| | | | NISA | Albion San Diego | 1 |
| | | | USLC | San Diego Loyal SC | 2 |
| NPSL | Hartford City FC | 0 | USLC | Hartford Athletic | 3 |
| LQ | Oyster Bay United FC | 3 | LQ | Oyster Bay United FC | 1 |
| | | | NISA | Bay Cities FC | 2 |
| | | | USLC | Monterey Bay FC | 1 |
| USL2 | South Carolina United | 0 | USL1 | Charlotte Independence | 2 |
| USL2 | North Carolina Fusion U23 | 1 | USL2 | North Carolina Fusion U23 | 4 |
| | | | USLC | Charleston Battery | 0 |
| | | | USL1 | South Georgia Tormenta FC | 1 |
| USL2 | The Villages SC | 6 | USLC | Tampa Bay Rowdies | 6 |
| LQ | Orlando FC Wolves | 0 | USL2 | The Villages SC | 0 |
| | | | NISA | Chattanooga FC | 3 |
| | | | USLC | Memphis 901 FC | 1 |
| NPSL | Denton Diablos FC | 2 | USLC | San Antonio FC | 3 |
| LQ | D'Feeters Kicks Soccer Club | 3 | LQ | D'Feeters Kicks Soccer Club | 1 |
| | | | USLC | Colorado Springs Switchbacks FC | 0 |
| | | | USL1 | Northern Colorado Hailstorm FC | 1* |
| NPSL | Southern States Soccer Club | 3 | USLC | Birmingham Legion FC | 2 |
| NPSL | Georgia Revolution FC | 1 | NPSL | Southern States Soccer Club | 1 |
| | | | USLC | Detroit City FC | 3 |
| | | | NISA | Michigan Stars FC | 0 |
| LQ | San Fernando Valley FC | 6 | NISA | California United Strikers FC | 5 |
| LQ | Escondido FC | 2 | LQ | San Fernando Valley FC | 0 |
| | | | USLC | El Paso Locomotive FC | 1 |
| | | | USL1 | Central Valley Fuego FC | 4 |
| LQ | Lynchburg FC | 1 | USL1 | Richmond Kickers | 1 |
| LQ | Northern Virginia FC | 3 | LQ | Northern Virginia FC | 0 |
| | | | USL1 | FC Tucson | 3 |
| | | | USLC | Las Vegas Lights FC | 2 |
| USL2 | Ocean City Nor'easters | 1 (3) | MLSNP | Rochester New York FC | 1 |
| NAC | Lansdowne Yonkers FC | 1 (4) | NAC | Lansdowne Yonkers FC | 0 |
| | | | USL1 | Greenville Triumph SC | 2 |
| | | | USLC | Oakland Roots SC | 0 |
| NPSL | Cleveland SC | 2* | USL1 | Forward Madison FC | 3 |
| USL2 | Chicago FC United | 1 | NPSL | Cleveland SC | 0 |
| | | | USLC | Louisville City FC | 1 |
| | | | USL1 | Chattanooga Red Wolves SC | 0 |
| NPSL | Miami United FC | 3 | USLC | Miami FC | 3 |
| LQ | City Soccer FC | 1 | NPSL | Miami United FC | 0 |
| | | | USL1 | North Carolina FC | 1 |
| | | | USLC | Rio Grande Valley FC | 2 |
| USL2 | Western Mass Pioneers | 2 | NISA | Flower City Union | 1* |
| LQ | Brockton FC United | 0 | USL2 | Western Mass Pioneers | 0 |
| | | | USLC | Orange County SC | 5 |
| | | | NISA | Los Angeles Force | 2 |
| USL2 | Des Moines Menace | 3 | USL1 | Union Omaha | 2 |
| NPSL | Minneapolis City SC | 2 | USL2 | Des Moines Menace | 1 |
| | | | USLC | Phoenix Rising FC | 1* |
| | | | NISA | Valley United FC | 0 |
| NPSL | Tulsa Athletic | 3 | USLC | FC Tulsa | 2 |
| LQ | Azteca FC | 0 | NPSL | Tulsa Athletic | 1 |
| | | | USLC | Pittsburgh Riverhounds SC | 2 |
| | | | NISA | Maryland Bobcats FC | 0 |
| USL2 | Portland Timbers U23s | 2 | USLC | Sacramento Republic FC | 6 |
| LQ | Contra Costa FC | 1 | USL2 | Portland Timbers U23s | 0 |
| | | | MLSNP | St. Louis City SC 2 | 2 |
| | | | USLC | Indy Eleven | 0 |
| NPSL | Las Vegas Legends | 3 | USLC | New Mexico United | 5 |
| USL2 | Park City Red Wolves SC | 2 | NPSL | Las Vegas Legends | 0 |
Host team listed first Bold = winner * = after extra time, ( ) = penalty shootout score

### First round

All times local to game site.

### Second round

All times local to game site.

## Third round

The winners of the second round and the new entrants to the tournament were grouped geographically into groups of four (12 groups) or six (eight groups), depending on the distribution of teams after the second round. Division I (MLS) teams entering the tournament were spread among the groups as evenly as possible (groups of four: five groups with two and seven groups with one MLS team; groups of six: one group with three and seven groups with two MLS teams). All MLS teams faced a lower-division team. Random selection for each group determined the pairs. Instances where geographical fit didn't exist when creating groups was resolved by random selection.
Teams for Third round draw :
| Previous round winners | New entrants (MLS) |
| FC Motown (NPSL) North Carolina Fusion U23 (USL2) Rochester New York FC (MLSNP) St. Louis City SC 2 (MLSNP) Bay Cities FC (NISA) California United Strikers FC (NISA) Chattanooga FC (NISA) Flower City Union (NISA) Central Valley Fuego FC (USL1) Forward Madison FC (USL1) Greenville Triumph SC (USL1) Northern Colorado Hailstorm FC (USL1) Richmond Kickers (USL1) South Georgia Tormenta FC (USL1) FC Tucson (USL1) Union Omaha (USL1) Birmingham Legion FC (USLC) Detroit City FC (USLC) Hartford Athletic (USLC) Louisville City FC (USLC) Miami FC (USLC) New Mexico United (USLC) Orange County SC (USLC) Phoenix Rising FC (USLC) Pittsburgh Riverhounds SC (USLC) Rio Grande Valley FC (USLC) Sacramento Republic FC (USLC) San Antonio FC (USLC) San Diego Loyal SC (USLC) Tampa Bay Rowdies (USLC) FC Tulsa (USLC) | Atlanta United FC Austin FC Charlotte FC Chicago Fire FC FC Cincinnati Columbus Crew D.C. United FC Dallas Houston Dynamo FC Inter Miami CF Los Angeles FC LA Galaxy Minnesota United FC New York Red Bulls Orlando City SC Real Salt Lake San Jose Earthquakes |
Draw Groups :
| North | Northeast | Southern California | Texas | Central | Florida | Mountain | Northern California | Piedmont | Southeast |
| Chicago Fire FC (MLS) Minnesota United FC (MLS) Louisville City FC (USLC) St. Louis City SC 2 (MLSNP) Forward Madison FC (USL1) Union Omaha (USL1) | D.C. United (MLS) New York Red Bulls (MLS) Hartford Athletic (USLC) Rochester New York FC (MLSNP) Flower City Union (NISA) FC Motown (NPSL) | Los Angeles FC (MLS) LA Galaxy (MLS) Orange County SC (USLC) San Diego Loyal SC (USLC) FC Tucson (USL1) California United Strikers FC (NISA) | Austin FC (MLS) FC Dallas (MLS) Houston Dynamo FC (MLS) Rio Grande Valley FC (USLC) San Antonio FC (USLC) FC Tulsa (USLC) | FC Cincinnati (MLS) Columbus Crew (MLS) Detroit City FC (USLC) Pittsburgh Riverhounds SC (USLC) | Inter Miami CF (MLS) Orlando City SC (MLS) Miami FC (USLC) Tampa Bay Rowdies (USLC) | Real Salt Lake (MLS) New Mexico United (USLC) Phoenix Rising FC (USLC) Northern Colorado Hailstorm FC (USL1) | San Jose Earthquakes (MLS) Sacramento Republic FC (USLC) Bay Cities FC (NISA) Central Valley Fuego FC (USL1) | Charlotte FC (MLS) Greenville Triumph SC (USL1) Richmond Kickers (USL1) North Carolina Fusion U23 (USL2) | Atlanta United FC (MLS) Birmingham Legion FC (USLC) Chattanooga FC (NISA) South Georgia Tormenta FC (USL1) |
All times local to game site.

## Round of 32

The winners of the Third Round and the new entrants to the tournament were grouped geographically into groups of four (eight groups). Each group had one of the MLS teams entering this round. Random selection for each group determined the pairs. Instances where geographical fit didn't exist when creating groups was resolved by random selection. The draw for the Round of 32 took place on April 21.
Teams for Round of 32 Draw :
| Previous Round winners | New Entrants (MLS) |
| Rochester New York FC (MLSNP) California United Strikers FC (NISA) Northern Colorado Hailstorm FC (USL1) Richmond Kickers (USL1) South Georgia Tormenta FC (USL1) Union Omaha (USL1) Detroit City FC (USLC) Louisville City FC (USLC) Phoenix Rising FC (USLC) Sacramento Republic FC (USLC) San Antonio FC (USLC) Atlanta United FC (MLS) Charlotte FC (MLS) FC Cincinnati (MLS) D.C. United (MLS) FC Dallas (MLS) Houston Dynamo FC (MLS) Inter Miami CF (MLS) LA Galaxy (MLS) Los Angeles FC (MLS) Minnesota United FC (MLS) New York Red Bulls (MLS) Orlando City SC (MLS) San Jose Earthquakes (MLS) | Colorado Rapids Nashville SC New England Revolution New York City FC Philadelphia Union Portland Timbers Seattle Sounders FC Sporting Kansas City |
Draw Groups :
| East Central | North Central | Northern Atlantic | Northern Pacific | South | South Central | Southern Atlantic | Southern Pacific |
| FC Cincinnati (MLS) New England Revolution (MLS) Detroit City FC (USLC) Louisville City FC (USLC) | Colorado Rapids (MLS) Minnesota United FC (MLS) Northern Colorado Hailstorm FC (USL1) Union Omaha (USL1) | D.C. United (MLS) New York City FC (MLS) New York Red Bulls (MLS) Rochester New York FC (MLSNP) | Seattle Sounders FC (MLS) San Jose Earthquakes (MLS) Phoenix Rising FC (USLC) Sacramento Republic FC (USLC) | Atlanta United FC (MLS) Charlotte FC (MLS) Nashville SC (MLS) Richmond Kickers (USL1) | FC Dallas (MLS) Houston Dynamo FC (MLS) Sporting Kansas City (MLS) San Antonio FC (USLC) | Inter Miami CF (MLS) Orlando City SC (MLS) Philadelphia Union (MLS) South Georgia Tormenta FC (USL1) | LA Galaxy (MLS) Los Angeles FC (MLS) Portland Timbers (MLS) California United Strikers FC (NISA) |
All times local to game site.

## Round of 16 and Quarterfinals

The winners of the Round of 32 were grouped geographically into groups of four (four groups). Random selection for each group determined the pairs. The Round of 16/Quarterfinal draw took place on May 12 at 8:30 PM EDT on Futbol Americas on ESPN+.
Draw Groups :
| Central | Northeast | Southeast | West |
| Houston Dynamo FC (MLS) Minnesota United FC (MLS) Sporting Kansas City (MLS) Union Omaha (USL1) | Charlotte FC (MLS) New England Revolution (MLS) New York City FC (MLS) New York Red Bulls (MLS) | Inter Miami CF (MLS) Nashville SC (MLS) Orlando City SC (MLS) Louisville City FC (USLC) | LA Galaxy (MLS) Los Angeles FC (MLS) San Jose Earthquakes (MLS) Sacramento Republic FC (USLC) |
| Round of 16 May 24–25 | Round of 16 May 24–25 | Round of 16 May 24–25 | Quarterfinals June 21–22, 29 | Quarterfinals June 21–22, 29 | Quarterfinals June 21–22, 29 |
| MLS | Sporting Kansas City | 2 | | | |
| MLS | Houston Dynamo FC | 1 | | | |
| MLS | Houston Dynamo FC | 1 | MLS | Sporting Kansas City | 6 |
| Central | Central | Central | MLS | Sporting Kansas City | 6 |
| Central | Central | Central | USL1 | Union Omaha | 0 |
| MLS | Minnesota United FC | 1 | USL1 | Union Omaha | 0 |
| USL1 | Union Omaha | 2 | | | |
| MLS | New York Red Bulls | 3 | | | |
| MLS | Charlotte FC | 1 | | | |
| MLS | Charlotte FC | 1 | MLS | New York Red Bulls | 3 |
| Northeast | Northeast | Northeast | MLS | New York Red Bulls | 3 |
| Northeast | Northeast | Northeast | MLS | New York City FC | 0 |
| MLS | New York City FC | 1* | MLS | New York City FC | 0 |
| MLS | New England Revolution | 0 | | | |
| MLS | Orlando City SC | 1 (4) | | | |
| MLS | Inter Miami CF | 1 (2) | | | |
| MLS | Inter Miami CF | 1 (2) | MLS | Orlando City SC | 1 (6) |
| Southeast | Southeast | Southeast | MLS | Orlando City SC | 1 (6) |
| Southeast | Southeast | Southeast | MLS | Nashville SC | 1 (5) |
| USLC | Louisville City FC | 1 | MLS | Nashville SC | 1 (5) |
| MLS | Nashville SC | 2 | | | |
| MLS | LA Galaxy | 3 | | | |
| MLS | Los Angeles FC | 1 | | | |
| MLS | Los Angeles FC | 1 | MLS | LA Galaxy | 1 |
| West | West | West | MLS | LA Galaxy | 1 |
| West | West | West | USLC | Sacramento Republic FC | 2 |
| USLC | Sacramento Republic FC | 2 | USLC | Sacramento Republic FC | 2 |
| MLS | San Jose Earthquakes | 0 | | | |
Bold = winner * = after extra time, ( ) = penalty shoot-out score

### Round of 16

All times local to game site.

### Quarterfinals

All times local to game site.

## Semifinals and Final

The Quarterfinal winners were matched geographically to determine the pairings for the semifinal round. The draw to determine the home teams for the semifinals and the final was held on June 23.
| Semifinals July 27 | Semifinals July 27 | Semifinals July 27 | Final September 7 | Final September 7 | Final September 7 |
| MLS | Orlando City SC | 5 | | | |
| MLS | New York Red Bulls | 1 | | | |
| MLS | New York Red Bulls | 1 | MLS | Orlando City SC | 3 |
| | | | USLC | Sacramento Republic FC | 0 |
| USLC | Sacramento Republic FC | 0 (5) | USLC | Sacramento Republic FC | 0 |
| MLS | Sporting Kansas City | 0 (4) | | | |

### Semifinals

All times local to game site.

### Final
## Top goal scorers

| Rank | Player | Team | Goals | By round | By round | By round | By round | By round | By round | By round | By round |
| Rank | Player | Team | Goals | 1R | 2R | 3R | R32 | R16 | QF | SF | F |
| 1 | Rodrigo López | Sacramento Republic FC | 4 | | 1 | 1 | | 1 | 1 | | |
| 1 | Lucky Mkosana | Tampa Bay Rowdies | 4 | | 3 | 1 | | | | | |
| 1 | Facundo Torres | Orlando City SC | 4 | | | | | 1 | | 1 | 2 |
| 4 | Cristian Arango | Los Angeles FC | 3 | | | 2 | 1 | | | | |
| 4 | Álvaro Barreal | FC Cincinnati | 3 | | | 2 | 1 | | | | |
| 4 | Tomas Bosuel | San Fernando Valley FC | 3 | 3 | | | | | | | |
| 4 | Luis Felipe | Sacramento Republic FC | 3 | | | | 1 | 1 | 1 | | |
| 4 | Carles Gil | New England Revolution | 3 | | | | 3 | | | | |
| 4 | Dejan Joveljić | LA Galaxy | 3 | | | | 2 | 1 | | | |
| 4 | Lewis Morgan | New York Red Bulls | 3 | | | 1 | | | 1 | 1 | |
| 4 | Hany Mukhtar | Nashville SC | 3 | | | | 1 | 1 | 1 | | |
| 4 | Maxi Rodriguez | Detroit City FC | 3 | | | 2 | 1 | | | | |
| 13 | David Achaerandio Martín | Escondido FC | 2 | 2 | | | | | | | |
| 13 | César Araújo | Orlando City SC | 2 | | | | | | | 2 | |
| 13 | Luiz Araújo | Atlanta United FC | 2 | | | 1 | 1 | | | | |
| 13 | Villyan Bijev | Central Valley Fuego FC | 2 | | 2 | | | | | | |
| 13 | Adam Buksa | New England Revolution | 2 | | | | 2 | | | | |
| 13 | Kévin Cabral | LA Galaxy | 2 | | | 1 | | 1 | | | |
| 13 | Evan Conway | San Diego Loyal SC | 2 | | 2 | | | | | | |
| 13 | Cade Cowell | San Jose Earthquakes | 2 | | | 1 | 1 | | | | |
| 13 | Rafael Czichos | Chicago Fire FC | 2 | | | 2 | | | | | |
| 13 | Dom Dwyer | Atlanta United FC | 2 | | | 2 | | | | | |
| 13 | Lucas Espíndola | Miami United FC | 2 | 2 | | | | | | | |
| 13 | McKinze Gaines | Charlotte FC | 2 | | | | 2 | | | | |
| 13 | Wilson Harris | Louisville City FC | 2 | | 1 | | 1 | | | | |
| 13 | Felipe Hernández | Sporting Kansas City | 2 | | | | | | 2 | | |
| 13 | Adrien Hunou | Minnesota United FC | 2 | | | 1 | | 1 | | | |
| 13 | Franco Jara | FC Dallas | 2 | | | 1 | 1 | | | | |
| 13 | Ola Kamara | D.C. United | 2 | | | 2 | | | | | |
| 13 | Jake Keegan | Greenville Triumph SC | 2 | | 1 | 1 | | | | | |
| 13 | Jerome Kiesewetter | New Mexico United | 2 | | 2 | | | | | | |
| 13 | Duke Lacroix | Sacramento Republic FC | 2 | | 2 | | | | | | |
| 13 | Ariel Lassiter | Inter Miami CF | 2 | | | | 2 | | | | |
| 13 | Matt Lewis | Detroit City FC | 2 | | 2 | | | | | | |
| 13 | Tony López | California United Strikers FC | 2 | | 2 | | | | | | |
| 13 | Luquinhas | New York Red Bulls | 2 | | | | 1 | | 1 | | |
| 13 | Sebastian Mendez | D'Feeters Kicks Soccer Club | 2 | 1 | 1 | | | | | | |
| 13 | Noe Meza | Union Omaha | 2 | | | 1 | 1 | | | | |
| 13 | Benji Michel | Orlando City SC | 2 | | | | | | | 1 | 1 |
| 13 | Danny Musovski | Los Angeles FC | 2 | | | 2 | | | | | |
| 13 | Daniel Ríos | Charlotte FC | 2 | | | | 1 | 1 | | | |
| 13 | Johnny Russell | Sporting Kansas City | 2 | | | | | 2 | | | |
| 13 | Henrik Sakshaug | San Antonio FC | 2 | | 2 | | | | | | |
| 13 | Dániel Sallói | Sporting Kansas City | 2 | | | | | | 2 | | |
| 13 | Alessandro Salvadego | Des Moines Menace | 2 | 2 | | | | | | | |
| 13 | Khiry Shelton | Sporting Kansas City | 2 | | | | 1 | | 1 | | |
| 13 | Tom Shepherd | Southern States SC | 2 | 2 | | | | | | | |
| 13 | Jack Skahan | San Jose Earthquakes | 2 | | | 1 | 1 | | | | |
| 13 | Toby Sims | Pittsburgh Riverhounds SC | 2 | | 2 | | | | | | |
| 13 | Rafael Vacas Barba | The Villages SC | 2 | 2 | | | | | | | |

## Broadcasting

First Round matches were split between ESPN+ and U.S. Soccer's YouTube channel; all matches from the second round to the final were broadcast on ESPN+. This is the final year of a four-year agreement between ESPN and U.S. Soccer to broadcast the tournament. Warner Bros. Discovery Sports will have the rights starting in 2023, as part of an 8-year agreement with U.S. Soccer.