# List of indigenous languages of South America

This article lists the indigenous languages of South America. Extinct languages are marked by dagger signs (†).

## Demographics by country

Demographics of Indigenous languages of South America by country as of 2012, as reported by Crevels (2012):
| Language | Alternate names | Family | Branch | Population | Speaker number | Degree of endangerment | Country | Other countries |
| Mapudungun | Mapuche | Araucanian | | 113,680 | 8,413 | seriously endangered | Argentina | Chile |
| Aymara | | Aymaran | | 4,104 | ? | endangered | Argentina | Chile, Bolivia, Peru |
| Gününa Yajich | Gününa Küne, Pampa | Chonan | | 1,585 | – | extinct (1960–1970) | Argentina | |
| Selkʼnam | Ona | Chonan | | 696 | – | extinct (1970s) | Argentina | Chile † |
| Tehuelche | Aonekʼenk, Pʼe꞉nkʼenk | Chonan | | 10,590 | 3 | moribund | Argentina | |
| Teushen | Tehuesh | Chonan | | – | – | extinct (early 1900s) | Argentina | |
| Mocoví | Moqoyt Laʼqa꞉tqa | Guaicuruan | | 15,837 | 2,780 | endangered | Argentina | |
| Pilagá | PitelaGa Laqtak | Guaicuruan | | 4,465 | 3,494 | potentially endangered | Argentina | |
| Toba | Namqom | Guaicuruan | | 69,452 | 30,410 | endangered | Argentina | Paraguay |
| Vilela | | Lule-Vilelan | | 50 | 2 | moribund | Argentina | |
| Chorote | Yofuáha, Yowúwa | Matacoan | | 2,613 | 1,692 | endangered | Argentina | Paraguay |
| Nivaclé | Nivaklé, Chulupí, Ashluslay | Matacoan | | 553 | 224 | seriously endangered | Argentina | Paraguay |
| Wichí | Mataco, ʼWeenhayek in Bolivia | Matacoan | | 40,036 | 28,631 | potentially endangered | Argentina | Bolivia |
| Santiagueño Quechua | | Quechuan | | – | 60,000 – 80,000 | endangered | Argentina | |
| Ava Guaraní | Guaraní in Bolivia, Guaraní Occidental in Paraguay | Tupían | Tupí-Guaranían | 21,807 | 5,139 | endangered | Argentina | Bolivia |
| Guaraní Correntino | Guaraní Goyano | Tupían | Tupí-Guaranían | – | 100,000 – 1,000,000 | potentially endangered | Argentina | |
| Mbyá | | Tupían | Tupí-Guaranían | 8,223 | 3,908 | endangered | Argentina | Paraguay, Brazil |
| Tapieté | Ñandevá in Paraguay | Tupían | Tupí-Guaranían | 524 | 178 | seriously endangered | Argentina | Bolivia, Paraguay |
| Kunza | Atacameño, Likan Antai, Ulipe, Lipe | Isolate | | 3,044 | – | extinct | Argentina | Chile † |
| Yahgan | Yámana | Isolate | | – | – | extinct (late 1900s) | Argentina | Chile |
| Quechua | | Quechuan | | 2,125,000 | 1,540,833 | potentially endangered | Bolivia | Peru, Ecuador, Colombia, Chile, Argentina |
| Aymara | | Aymaran | | 1,470,000 | 1,008,825 | potentially endangered | Bolivia | Peru, Chile, Argentina |
| Chipaya | | Uru-Chipayan | | 2,134 | 1,800 | endangered | Bolivia | |
| Uchumataqu | Uru | Uru-Chipayan | | 230 | – | extinct (2004) | Bolivia | |
| Chholo | | Uru-Chipayan | | ? | 1? | extinct | Bolivia | |
| Puquina | | Puquinan | | – | – | extinct | Bolivia | Peru † |
| Kallawaya | | Mixed | | – | ? | seriously endangered | Bolivia | |
| Machineri | | Arawakan | | 30 | 13 | seriously endangered | Bolivia | Brazil |
| Baure | | Arawakan | | 886 | 67 | seriously endangered | Bolivia | |
| Moxo (Mojeño), Trinitario | | Arawakan | | 30,000 | 3,140 | endangered | Bolivia | |
| Moxo (Mojeño), Ignaciano | | Arawakan | | 2,000 | 1,080 | seriously endangered | Bolivia | |
| Paunaca | | Arawakan | | ? | 5 | moribund | Bolivia | |
| Moré | Itene | Chapacuran | | 64 | 44 | seriously endangered | Bolivia | |
| Chácobo | | Pano-Tacanan | Tacanan | 516 | 380 | endangered | Bolivia | |
| Pacahuara | | Pano-Tacanan | Tacanan | 46 | 6 | moribund | Bolivia | |
| Yaminahua | | Pano-Tacanan | Tacanan | 93 | 51 | seriously endangered | Bolivia | Peru, Brazil |
| Ese Ejja | | Pano-Tacanan | Tacanan | 732 | 518 | endangered | Bolivia | Peru |
| Araona | | Pano-Tacanan | Tacanan | 158 | 111 | seriously endangered | Bolivia | |
| Cavineña | | Pano-Tacanan | Tacanan | 1,683 | 601 | endangered | Bolivia | |
| Tacana | | Pano-Tacanan | Tacanan | 7,345 | 1,153 / 50–500 | seriously endangered | Bolivia | |
| Maropa | Reyesano | Pano-Tacanan | Tacanan | 4,919 | 53 / 12 | moribund | Bolivia | |
| Yuki | | Tupían | Tupí-Guaranían | 208 | 140 | seriously endangered | Bolivia | |
| Sirionó | | Tupían | Tupí-Guaranían | 268 | 187 | endangered | Bolivia | |
| Guarayo | | Tupían | Tupí-Guaranían | 11,953 | 8,433 | potentially endangered | Bolivia | |
| Guaraní | Chiriguano | Tupían | Tupí-Guaranían | 125,159 | 43,633 | potentially endangered | Bolivia | Argentina |
| Tapieté | | Tupían | Tupí-Guaranían | 41 | 29 | seriously endangered | Bolivia | Argentina, Paraguay |
| ʼWeenhayek | Mataco, Wichí in Argentina | Matacoan | | 1,797 | 1,929 | endangered | Bolivia | Argentina |
| Ayoreo | | Zamucoan | | 1,398 | 1,398 | endangered | Bolivia | Paraguay |
| Canichana | | Isolate | | 404 | 4 / 0? | extinct | Bolivia | |
| Movima | | Isolate | | 12,230 | 1,173 | seriously endangered | Bolivia | |
| Cayubaba | | Isolate | | 664 | 23 / <3 | moribund | Bolivia | |
| Itonama | | Isolate | | 2,791 | 389 / < 2 | moribund | Bolivia | |
| Mosetén | | Mosetenan | | 1,588 | 948 | endangered | Bolivia | |
| Tsimaneʼ | Chimane | Mosetenan | | 8,615 | 6,351 | potentially endangered | Bolivia | |
| Leko | | Isolate | | 4,186 | 132 / 20 | moribund | Bolivia | |
| Yurakaré | | Isolate | | 2,829 | 1,809 | endangered | Bolivia | |
| Besïro | Chiquitano | Macro-Gê | Chiquitano | 195,624 | 4,615 | seriously endangered | Bolivia | Brazil |
| Banawá Yafí | Banawá | Arawan | | 100 (2006) | 100 | seriously endangered | Brazil | |
| Deni | | Arawan | | 875 (2006) | 875 | endangered | Brazil | |
| Jamamadí | Yamamadí, Kanamantí | Arawan | | 884 (2006) | 800 | endangered | Brazil | |
| Jarawara | Jarauara | Arawan | | 180 (2006) | 180 | endangered | Brazil | |
| Kulina | Culina, Madihá, Madiha, Madija | Arawan | | 3,500 (2006) | 3,000 | endangered | Brazil | Peru |
| Paumari | Palmari | Arawan | | 892 (2006) | 290 (2000) | seriously endangered | Brazil | |
| Zuruahã | Sorowaha, Suruwaha | Arawan | | 136 (2007) | 136 | seriously endangered | Brazil | |
| Apurinã | Popingaré, Kangitê, Kaxiriri, Cacharary | Arawakan | | 3,256 (2006) | 2,000 | endangered | Brazil | |
| Asháninka | Kampa, Axíninka | Arawakan | | 869 (2004) | 813 | endangered | Brazil | Peru |
| Baniwa | Baniwa do Içana, Baniva, Baniua, Walimanai, Wakuenai | Arawakan | | 5,811 (2005) | 5,811 | potentially endangered | Brazil | Colombia, Venezuela |
| Baré | | Arawakan | | 10,275 (2005) | 2 | moribund | Brazil | Venezuela |
| Enawê-Nawê | Salumã | Arawakan | | 445 (2006) | 445 | endangered | Brazil | |
| Kaixana | Caixana | Arawakan | | 505 (2006) | 1 | moribund | Brazil | |
| Kinikinau | Guaná | Arawakan | | 250 (2005) | 11 (2007) | moribund | Brazil | |
| Kuripako | Curripaco, Curipaco, Coripaco | Arawakan | | 1,332 (2005) | 1,332 | endangered | Brazil | Colombia, Venezuela |
| Machineri | Manchineri, Yine | Arawakan | | 937 (2004) | 937 | endangered | Brazil | Bolivia |
| Mehinako | Mehinaku, Meinaku | Arawakan | | 227 (2006) | 200 | seriously endangered | Brazil | |
| Palikur | Palikuʼene, Aukwayene, Aukuyene | Arawakan | | 1,330 (2006) | 1,300 | endangered | Brazil | French Guiana |
| Parecí | Paresí, Arití, Halití | Arawakan | | 2,005 (2008) | 1,000 | endangered | Brazil | |
| Tariana | Tariano | Arawakan | | 1,914 (2002) | 100 | seriously endangered | Brazil | Colombia |
| Terêna | Terena, Tereno | Arawakan | | 19,961 | 19,000 | potentially endangered | Brazil | |
| Wapixana | Wapishana, Wapisiana, Uapixana, Vapidiana | Arawakan | | 7,000 (2008) | 4,000? | endangered | Brazil | Guyana |
| Warekena | Werekena, Uarequena | Arawakan | | 806 (206) | 20 | seriously endangered | Brazil | Venezuela |
| Waurá | Waujá, Uará | Arawakan | | 321 (2008) | 321 | endangered | Brazil | |
| Yawalapití | Iaualapití | Arawakan | | 222 (2006) | 10? | moribund | Brazil | |
| Bakairí | Bacairí, Kurâ | Cariban | | 950 (1999) | 950 | endangered | Brazil | |
| Galibí | Galibí do Oiapoque, Kariʼna, Kaliña | Cariban | | 66 | only elders | seriously endangered | Brazil | Venezuela, French Guiana, Suriname, Guyana |
| Hixkaryana | Hyxkaryana | Cariban | | 631 (2006) | 600 | endangered | Brazil | |
| Ikpeng | Txicão, Txikão | Cariban | | 342 (2006) | 342 | endangered | Brazil | |
| Ingarikó | Akawayo, Kapon | Cariban | | 1,170 (2007) | 1,170 | endangered | Brazil | Guyana, Venezuela |
| Kalapalo | Calapalu | Cariban | | 506 (2006) | 506 | endangered | Brazil | |
| Katxuyana-Xikuyana | Kaxuyana-Xikuyana, Kaxuyana, Caxuiana | Cariban | | 230 (2006) | 150 | seriously endangered | Brazil | |
| Kuikuro | Cuicuro | Cariban | | 509 (2006) | 600 | endangered | Brazil | |
| Makuxí | Macuxi, Macushi, Pemon | Cariban | | 23,433 (2006) | 15,000 | potentially endangered | Brazil | Venezuela |
| Matipú | | Cariban | | 103 (2006) | 10 | moribund | Brazil | |
| Nahukwá | Nahukuá, Nafuquá | Cariban | | 124 (2006) | 124 | seriously endangered | Brazil | |
| Naruvoto | | Cariban | | 78 (2003) | ? | seriously endangered | Brazil | |
| Patamona | Kapon, Akawayo | Cariban | | 87 (2006) | ? | seriously endangered | Brazil | Guyana, Venezuela |
| Taurepang | Taulipang, Pemon, Arekuna | Cariban | | 582 (2002) | 500 | seriously endangered | Brazil | Guyana, Venezuela |
| Tiriyó | Trio, Tarëno, Tirió, Tirio, Tarona, Yawi, Pianokoto | Cariban | | 1,156 (2006) | 1,156 | endangered | Brazil | Suriname |
| Waimirí-Atroarí | Kinã, Kinja | Cariban | | 1,120 (2005) | 1,120 | endangered | Brazil | |
| Waiwai | Wai Wai, TunayanaWaiwai, Katuena | Cariban | | 2,914 (2005) | 2,914 | potentially endangered | Brazil | Guyana |
| Wayana | Waiana, Uaiana, Aparaí | Cariban | | 288 (2006) | 288 | endangered | Brazil | Suriname, French Guiana |
| Yekuana | Yeʼkuana, Yekwana, Yecuana, Makiritare, Maquiritare, Maiongong, Soʼto | Cariban | | 430 (2000) | 430 | endangered | Brazil | Venezuela |
| Kuyubim | Kujubí, Cojubím, Kaw Ta Yo | Chapacuran | | 55 (2006) | 2 (2001) | moribund | Brazil | |
| Miguelenho | Uomo | Chapacuran | | 50 | 1 | moribund | Brazil | |
| Moré | | Chapacuran | | 30 (2002) | 12 (2002) | seriously endangered | Brazil | Bolivia |
| Oro Win | Oro Towati | Chapacuran | | 56 (2006) | 5 | moribund | Brazil | |
| Torá | | Chapacuran | | 312 (2006) | – | extinct | Brazil | |
| Wariʼ | Pakaa Nova, Pacaás Novos | Chapacuran | | 2,721 (2006) | 2,721 | potentially endangered | Brazil | |
| Kadiweu | Kadiweo, Caduveo, Cadiuéu, Ejiwajigi, Mbaya-Guaicuru | Guaicuruan | | 1,629 (2006) | 1,600 | endangered | Brazil | |
| Kanamarí | Canamarí, Tüküná, Tâkâna | Harakmbut-Katukinan | | 1,654 (2006) | most? | endangered | Brazil | |
| Katawixí | Catawixi, Catauixi, Catawishi | Harakmbut-Katukinan | | 10? (1986) | 10? | seriously endangered | Brazil | |
| Katukina do Biá | Pedá Djapá, Tüküná | Harakmbut-Katukinan | | 450 (2007) | 1 (1976) | possibly extinct | Brazil | |
| Tsohom Djapá | Tucano | Harakmbut-Katukinan | | 100 (1985) | 30? | seriously endangered | Brazil | |
| Bororo | Eastern Bororo, Boe, Boe Wadáru | Macro-Gê | Bororo | 1,390(2006) | 1,390 | endangered | Brazil | |
| Umutina | Omotina, Barbados | Macro-Gê | Bororo | 445 (2009) | – | extinct | Brazil | |
| Chiquitano | Linguará, Anenho | Macro-Gê | Chiquitano | 737 (2006) | 50 | seriously endangered | Brazil | Bolivia |
| Guató | | Macro-Gê | Guató | 370 (2006) | 5 | moribund | Brazil | |
| Apinajé | Apinayé, Apinaié, Timbira Ocidentais | Macro-Gê | Gêan | 1,525 (2006) | 1,500 | endangered | Brazil | |
| Canela | Kanela, Kanela Ramkokamekrá, Kanela Apanyekra | Macro-Gê | Gêan | 2,502 (2006) | 2,502 | endangered | Brazil | |
| Gavião Perkatêjê | Gavião, Parkatêjê, Gavião do Pará, Gavião do Mãe Maria | Macro-Gê | Gêan | 476 (2006) | 476 | endangered | Brazil | |
| Gavião Pukobiê | Pykopjê, Gavião do Maranhão, Timbira | Macro-Gê | Gêan | 494 (2006) | 494 | endangered | Brazil | |
| Kaingang | Caingangue, Kanhgág | Macro-Gê | Gêan | 28,000 (2006) | 18,500 | potentially endangered | Brazil | |
| Krahô | Craô, Kraô, Mehim, Timbira | Macro-Gê | Gêan | 2,184 (2006) | 2,184 | endangered | Brazil | |
| Kren-Yê | | Macro-Gê | Gêan | 30 (1999) | 1 (1981) | extinct | Brazil | |
| Krikatí | Krinkatí, Krikatí-Timbira, Timbira | Macro-Gê | Gêan | 682 (2005) | 682 | endangered | Brazil | |
| Mebêngokrê | Kayapó, Xikrin, Put Karot | Macro-Gê | Gêan | 7,266 (2006) | 7,266 | potentially endangered | Brazil | |
| Panará | Krenhakarore, Krenakore, Krenakarore, Kreen-Akarore, Índios Gigantes | Macro-Gê | Gêan | 374 (2008) | 374 | endangered | Brazil | |
| Kisêdjê | Suyá, Suiá, Mëkisêdjê | Macro-Gê | Gêan | 351 (2006) | 351 | endangered | Brazil | |
| Tapayuna | Suyá Orientais, Novos Suyá, Beiço-de-Pau | Macro-Gê | Gêan | 58 (1995) | 58? | seriously endangered | Brazil | |
| Xakriabá | Xacriabá, Xikriabá | Macro-Gê | Gêan | 7,665 (2006) | 0? | possibly extinct | Brazil | |
| Xavante | Aʼuwe, Awen | Macro-Gê | Gêan | 13,303 (2007) | 13,303 | potentially endangered | Brazil | |
| Xerente | Akwê, Akwen, Acuen | Macro-Gê | Gêan | 2,569 (2006) | 2,569 | potentially endangered | Brazil | |
| Xokleng | Shokleng, Xokrén, Laklanô, Bugres, Botocudos, Aweikoma, Kaingang de Santa Catarina, Aweikoma-Kaingang | Macro-Gê | Gêan | 887 (2004) | 100 | seriously endangered | Brazil | |
| Arikapú | Aricapú | Macro-Gê | Jabutí | 30 (2006) | 1 | moribund | Brazil | |
| Djeoromitxí | Jeoromitxí, Jabutí | Macro-Gê | Jabutí | 165 (2006) | 30 (2008) | seriously endangered | Brazil | |
| Yatê | Iatê, Fulniô, Carnijó | Macro-Gê | Yatê | 2,930 (1999) | 1,000 | endangered | Brazil | |
| Javaé | Karajá | Macro-Gê | Karajá | 1,208 (2006) | 800? | endangered | Brazil | |
| Karajá | Carajá, Iny | Macro-Gê | Karajá | 2,532 (2006) | 2,250 | endangered | Brazil | |
| Xambioá | Karajá do Norte, Ixybiowa, Iraru Mahãdu | Macro-Gê | Karajá | 269 (2006) | 10 | moribund | Brazil | |
| Krenak | Crenaque, Crenac, Krenac, Nakrehé, Krenak-Nakrehé, Borun; Botocudos; Aimorés | Macro-Gê | Krenakan | 204 (2006) | 10 | moribund | Brazil | |
| Maxakalí | Maxacalí, Monacó, Kumanuxú, Tikmuún | Macro-Gê | Maxakalí | 1,271 (2006) | 1,271 | endangered | Brazil | |
| Pataxó | Pataxó do Norte, Pataxó do Sur, Hã Hã Hãe | Macro-Gê | Maxakalí | 2,219 (2005) | – | extinct (late 1900s) | Brazil | |
| Ofayé | Ofaié, Opayé, Ofayé-Xavante | Macro-Gê | Ofayé | 61 (2006) | 12 | seriously endangered | Brazil | |
| Rikbaktsá | Erikbaktsá, Erigpaktsá, Orelhas de Pau, Canoeiros | Macro-Gê | Rikbaktsá | 1,117 (2006) | 900 | endangered | Brazil | |
| Mura | | Muran | | 9,299 (2006) | – | extinct | Brazil | |
| Pirahã | Mura-Pirahã | Muran | | 389 (2006) | 389 | endangered | Brazil | |
| Dâw | Kamã | Nadahup | | 120 | 120 | seriously endangered | Brazil | |
| Hup | Hupdá, Hupdé, Hupdá Makú | Nadahup | | 1,500 | 1,500 | endangered | Brazil | Colombia |
| Kuyabi | Kuyawi | Nadahup | | 20 | 20 | seriously endangered | Brazil | |
| Nadëb | Nadöbö, Anodöb, Makunadöbö, Guariba, Guariba Tapuyo, Kabori, Xiriwai | Nadahup | | 350 | 350 | endangered | Brazil | |
| Yuhup | | Nadahup | | 617 | 617 | endangered | Brazil | Colombia |
| Latundê | Northern Nambikwara (Nambikwara do Norte) | Nambikwaran | | 19 | 19 | seriously endangered | Brazil | |
| Lakondê | Northern Nambikwara (Nambikwara do Norte) | Nambikwaran | | 7 | 1 | seriously endangered | Brazil | |
| Mamaindê | Northern Nambikwara (Nambikwara do Norte) | Nambikwaran | | 250 | 250 | endangered | Brazil | |
| Negarotê | Northern Nambikwara (Nambikwara do Norte) | Nambikwaran | | 80 | 80 | seriously endangered | Brazil | |
| Tawandê | Northern Nambikwara (Nambikwara do Norte) | Nambikwaran | | few | 1 | moribund | Brazil | |
| Southern Nambikwara | Nambikwara do Sul | Nambikwaran | | 721 | 721 | seriously endangered | Brazil | |
| Sabanê | | Nambikwaran | | 140 | 3 | moribund | Brazil | |
| Arara Shawãdawa | Arara do Acre, Shawanauá | Panotacanan | Panoan | 332 (2004) | 9 (2000) | moribund | Brazil | |
| Katukina-Kanamari | Katukina [Tüküná, Pi:Dyapa], Kanamarí [Tüküna Kanamarí, Canamari], Tsohom-Dyapa [Tsunhum-Djapá, Tyonhwak Dyapa], Katukina do Acre, Katukina Pano | Panotacanan | Panoan | 2,239 (2008) | 2,239 | potentially endangered | Brazil | |
| Kaxararí | Caxarari, Kaxariri | Panotacanan | Panoan | 322 (2009) | 300? | seriously endangered | Brazil | |
| Kaxinawá | Caxinauá, Cashinahuá, Cashinahua, Hantxa Kuin, Huni Kuin | Panotacanan | Panoan | 4,500 (2004) | 4,500 | potentially endangered | Brazil | Peru |
| Korubo | | Panotacanan | Panoan | 26 (2007) | 26 | seriously endangered | Brazil | |
| Kulina do Acre | Kulina Pano, Culina | Panotacanan | Panoan | 125 (2006) | only elders | seriously endangered | Brazil | |
| Marubo | | Panotacanan | Panoan | 1,252 (2006) | 1,252 | endangered | Brazil | |
| Matís | | Panotacanan | Panoan | 322 (2008) | 322 | endangered | Brazil | |
| Matsés | | Panotacanan | Panoan | 1,592 (2006) | 1,500 | endangered | Brazil | Peru |
| Maya | Quixito | Panotacanan | Panoan | 400 | 400 | endangered | Brazil | Peru? |
| Nukini | Nuquini, Nukuíni | Panotacanan | Panoan | 600 (2003) | – | extinct | Brazil | |
| Poyanawa | Poianáua | Panotacanan | Panoan | 403 (1999) | 2 | moribund | Brazil | |
| Shanenawá | Katukina, Shanenawá | Panotacanan | Panoan | 361 (2006) | 300 | endangered | Brazil | |
| Yaminawa | Jaminawa, Iauminawa | Panotacanan | Panoan | 855 (2006) | 600 | endangered | Brazil | Bolivia, Peru |
| Yawanawá | Yauanauá, Iauanauá | Panotacanan | Panoan | 519 (2006) | 519 | endangered | Brazil | |
| Arapaso | Arapaço | Tucanoan | | 569 | 0? | possibly extinct | Brazil | |
| Bará | Waimajã, Waípinõmakã | Tucanoan | | 21 (2005) | 21 | seriously endangered | Brazil | Colombia |
| Barasana | Barasano, Pãnerã, Hanera, Panenoá | Tucanoan | | 34 (2005) | 34 | seriously endangered | Brazil | Colombia |
| Desano | Desana, Dessano, Wira, Umúkomasá | Tucanoan | | 2,204 (2005) | 700 | endangered | Brazil | Colombia |
| Karapanã | Carapanã, Muteamasa, Ukopinõpõna | Tucanoan | | 63 (2005) | 63 | seriously endangered | Brazil | Colombia |
| Kotiria | Wanano, Wanana, Guanano, Uanano | Tucanoan | | 735 (2005) | 650 | endangered | Brazil | Colombia |
| Kubeo | Cubeo, Cobewa, Kubéwa, Pamíwa | Tucanoan | | 381 (2005) | 150–200 | seriously endangered | Brazil | Colombia |
| Makuna | Macuna, Yeba-Masã | Tucanoan | | 32 (2005) | 32 | seriously endangered | Brazil | Colombia |
| Mirity-Tapuya | Miriti-Tapuia, Buia-Tapuya | Tucanoan | | 75 (2005) | 0? | possibly extinct | Brazil | |
| Piratapuya | Piratapuia, PiraTapuia, Piratapuyo, Waíkana | Tucanoan | | 1,433 (2005) | 700 | seriously endangered | Brazil | Colombia |
| Siriano | Siria-Masã | Tucanoan | | 71 (2005) | 71? | seriously endangered | Brazil | Colombia |
| Tukano | Tucano, Yeʼpãmasa, Dasea | Tucanoan | | 6,241 (2005) | 7,000 | potentially endangered | Brazil | Colombia |
| Tuyuka | Tuyuca, Tuiuca, Dokapuara, Utapinõmakãphõná | Tucanoan | | 825 (2005) | 800? | endangered | Brazil | Colombia |
| Yurutí | Jurití | Tucanoan | | ? | 0? | possibly extinct | Brazil | Colombia |
| Karitiana | | Tupían | Arikem | 320 (2005) | 320 | endangered | Brazil | |
| Awetí | Aueti | Tupían | Awetí | 160 (2008) | 160 | seriously endangered | Brazil | |
| Aruá | | Tupían | Monde | 36 | 12 | seriously endangered | Brazil | |
| Cinta Larga | | Tupían | Monde | 645 | 645 | endangered | Brazil | |
| Gavião | Gavião de Rondônia, Ikõlej, Ikõleey, Ikõro | Tupían | Monde | 523 (2004) | 523 | endangered | Brazil | |
| Zoró | Pageyn | Tupían | Monde | 599 (2008) | 599 | endangered | Brazil | |
| Paiter | Suruí-Paiter, Suruí de Rondônia | Tupían | Monde | 1,007 (2006) | 1,007 | endangered | Brazil | |
| Salamãi | Sanamãika, Mondé | Tupían | Monde | ? | 2 | moribund | Brazil | |
| Kuruaya | Kuruaia, Curuaia | Tupían | Mundurukú | 129 (2006) | 3 | moribund | Brazil | |
| Mundurukú | Mundurucú | Tupían | Mundurukú | 10,065 (2002) | 8,000 | endangered | Brazil | |
| Puruborá | | Tupían | Puruborá | 62 (2006) | 2 | moribund | Brazil | |
| Karo | Arara, Arara Karo, Arara de Rondônia, Arara Tupi, Ntogapíd, Itoga-púk, Ramarama, Uruku, Urumi, Ytangá | Tupían | Ramaraman | 208 (2006) | 200 | seriously endangered | Brazil | |
| Sateré-Mawé | Sataré-Maué, Sateré, Mawé | Tupían | Sateré-Mawé | 9,156 (2008) | 6,219 | endangered | Brazil | |
| Ajurú | Wayurú, Wayoró | Tupían | Tuparían | 94 (2006) | 8 | seriously endangered | Brazil | |
| Akuntsú | Akuntʼsu, Akunsu | Tupían | Tuparían | 5 (2009) | 5 | moribund | Brazil | |
| Makurap | Macurap | Tupían | Tuparían | 381 (2006) | 50 | seriously endangered | Brazil | |
| Sakurabiat | Mekens, Mekém, Sakirabiat | Tupían | Tuparían | 84 (2006) | 22 (2008) | seriously endangered | Brazil | |
| Tuparí | | Tupían | Tuparían | 433 (2006) | 150 (2005) | seriously endangered | Brazil | |
| Amanayé | Amanaié, Ararandeuara | Tupían | Tupí-Guaranían | 192 (2001) | 0? | possibly extinct | Brazil | |
| Anambé | | Tupían | Tupí-Guaranían | 132 (2000) | 6 (2000) | moribund | Brazil | |
| Apiaká | Apiacá | Tupían | Tupí-Guaranían | 1,000 (2009) | 1 (2008) | moribund | Brazil | |
| Araweté | Araueté | Tupían | Tupí-Guaranían | 339 (2006) | 339 | endangered | Brazil | |
| Akwawa | varieties: Asuriní do Tocantins, Parakanã, Suruí do Tocantins | Tupían | Tupí-Guaranían | 1,548 | 1,548 | endangered | Brazil | |
| Asuriní do Tocantins | | Tupían | Tupí-Guaranían | 384 (2006) | 384 | endangered | Brazil | |
| Parakanã | Apiterewa | Tupían | Tupí-Guaranían | 900 (2004) | 900 | endangered | Brazil | |
| Suruí do Tocantins | | Tupían | Tupí-Guaranían | 264 (2006) | 264 | endangered | Brazil | |
| Asuriní do Xingu | Awaeté | Tupían | Tupí-Guaranían | 125 (2006) | 125 | seriously endangered | Brazil | |
| Avá-Canoeiro | Canoeiro, Carijó, Índios Negros, Cara Preta | Tupían | Tupí-Guaranían | 16 | 16? | seriously endangered | Brazil | |
| Diahoi | Jiahui, Jahói, Djahui, Diahkoi, Diarroi | Tupían | Tupí-Guaranían | 88 | 1 | moribund | Brazil | |
| Guajá | Awá, Avá | Tupían | Tupí-Guaranían | 283 (2005) | 283 | endangered | Brazil | |
| Guajajara | Tenetehára, Zeʼegete | Tupían | Tupí-Guaranían | 19,471(2006) | 14,000 | potentially endangered | Brazil | |
| Juma | Yuma | Tupían | Tupí-Guaranían | 5 | 5 | moribund | Brazil | |
| Kaʼapor | Urubu-Kaapor, Kaaporté | Tupían | Tupí-Guaranían | 991 (2006) | 991 | endangered | Brazil | |
| Kayabí | Kaiabí, Caiabí | Tupían | Tupí-Guaranían | 1,619 (2006) | 1,000 | endangered | Brazil | |
| Kaiowa | Kaiova, Paï-Tavyterã | Tupían | Tupí-Guaranían | 20,000 (2003) | most? | endangered | Brazil | Paraguay |
| Kamaiurá | Camaiurá | Tupían | Tupí-Guaranían | 492 (2006) | 400 (2008) | endangered | Brazil | |
| Karipuna dialect [pt] (part of the Kagwahiva languages) | | Tupían | Tupí-Guaranían | 14 (2004) | 10 | moribund | Brazil | |
| Kokama | Kocama, Cocama | Tupían | Tupí-Guaranían | 9,000(2003) | 5 (1993) | moribund | Brazil | Peru, Colombia |
| Mbyá | | Tupían | Tupí-Guaranían | 6,000 (2003) | 6,000 | potentially endangered | Brazil | Argentina, Paraguay |
| Ñandeva | Ava-Guaraní or Chiripá in Paraguay | Tupían | Tupí-Guaranían | 13,000 (2008) | 13,000 | potentially endangered | Brazil | Paraguay |
| Nheengatu | Yeral, Língua Geral, Língua Geral Amazônica | Tupían | Tupí-Guaranían | | 3,000 (1977) | endangered | Brazil | Venezuela |
| Omagua | Kambeba, Kambewa, Cambeba | Tupían | Tupí-Guaranían | 347 | few? | moribund | Brazil | Peru |
| Parintintin | Kagwahiwa | Tupían | Tupí-Guaranían | 284 (2006) | 10 | moribund | Brazil | |
| Tapirapé | Tapiʼirape | Tupían | Tupí-Guaranían | 564 (2006) | 564 | endangered | Brazil | |
| Tembé | Timbé, Tenetehára, Turiwara | Tupían | Tupí-Guaranían | 1,425 (2006) | 60 | seriously endangered | Brazil | |
| Tenharim | Kagwahiwa | Tupían | Tupí-Guaranían | 699 (2006) | 350 | seriously endangered | Brazil | |
| Tupinamba | Coastal Tupi | Tupían | Tupí-Guaranían | 2,590 (2006) | – | extinct | Brazil | |
| Uru-Eu-Wau-Wau | Amondawa, Jupaú, Kawahíb | Tupían | Tupí-Guaranían | 183 (2006) | 183 | seriously endangered | Brazil | |
| Wajãpi | Wayãpy, Waiãpi, Guaiapi, Wayampi, Oyampi | Tupían | Tupí-Guaranían | 905 (2008) | 905 | endangered | Brazil | French Guiana |
| Xetá | Hetá | Tupían | Tupí-Guaranían | 86 (2006) | 8 | moribund | Brazil | |
| Zoʼé | Poturu, Joʼé | Tupían | Tupí-Guaranían | 177 (2003) | 177 | seriously endangered | Brazil | |
| Xipaya | Xipaia, Shipaya | Tupían | Tupí-Guaranían | 595 (2002) | 2 (2003) | moribund | Brazil | |
| Yudjá | Yuruna, Juruna, Jurûna | Tupían | Yuruna | 362 (2006) | 300? | seriously endangered | Brazil | |
| Witoto | Huitoto, Uitoto | Witotoan | Witotoan proper | 42 | ? | possibly extinct (in Brazil) | Brazil | Peru, Colombia |
| Miranha | Mirãnha, Miraña | Witotoan | Boran | 836 (2006) | – | extinct | Brazil | Colombia |
| Sánuma | Sanïma, Sánïma, Sánema | Yanomaman | | 462 (2006) | 462 | endangered | Brazil | Venezuela |
| Yanam | Ninam, Xirianá | Yanomaman | | 466 (2006) | 466 | seriously endangered | Brazil | Venezuela |
| Yanomam | Yanomae | Yanomaman | | 4,000 (2006) | 4,000 | potentially endangered | Brazil | Venezuela |
| Yanomami | Yanomamï, Yanomamõ, Yanomama, Yanoama | Yanomaman | | 6,000 (2006) | 6,000 | potentially endangered | Brazil | Venezuela |
| Chamacoco | Ishir | Zamucoan | | 1,572 (2002) | 1,572 | endangered | Brazil | Paraguay |
| Aikanã | Aikaná, Masaká, Kasupá, Huarí, Mondé, Tubarão | Isolate | | 200 | 150 | seriously endangered | Brazil | |
| Atikum | Aticum, Wamoé | Isolate | | 5,852 (1999) | – | extinct (1960s) | Brazil | |
| Iranxe | Irantxe, Manoki | Isolate | | 276 (2006) | 10 | seriously endangered | Brazil | |
| Myky | Menky, Munku | Isolate | | 80 (2000) | 80? | seriously endangered | Brazil | |
| Kanoê | Canoé, Kapixaná | Isolate | | 95 (2002) | 3 | moribund | Brazil | |
| Kwazá | Koaiá, Coaiá, Quaia | Isolate | | 40 (2008) | 25 | seriously endangered | Brazil | |
| Ticuna | Tikuna, Tukuna, Magüa | Isolate | | 35,000 (2008) | 35,000 | potentially endangered | Brazil | Colombia, Peru |
| Trumai | | Isolate | | 147 (2006) | 51 (2007) | seriously endangered | Brazil | |
| Tuxá | | Isolate | | 3,927 | 2 (1961) | extinct (1960s) | Brazil | |
| Arara do Aripuanã | Arara do Beiradão, Arara do Rio Branco | Unclassified | | 209 (2005) | – | extinct | Brazil | |
| Isolados do Massaco | | Unclassified | | 100? | 100? | seriously endangered | Brazil | |
| Isolados do Tanarú | | Unclassified | | 1 | 1 | moribund | Brazil | |
| Kambiwá | Cambiuá | Unclassified | | 2,820 | 2 (1961) | extinct | Brazil | |
| Kantaruré | | Unclassified | | 493 (2006) | – | extinct | Brazil | |
| Kapinawá | Capinauá | Unclassified | | 3,294 | – | extinct | Brazil | |
| Kariri | Cariri, Kipea, Kiriri, Dzubukuá; Tumbalalá | Unclassified | | ? 1,469 (2006) | – | extinct | Brazil | |
| Kiriri | Katembri, Kariri, Kariri de Mirandela | Unclassified | | 1,612 | 1 (1960s) | extinct | Brazil | |
| Máku | Macu, Mako | Unclassified | | ? | – | extinct (2000–2002) | Brazil | |
| Pankararu | Pancararu, Pankararé | Unclassified | | 6,515 | – | extinct | Brazil | |
| Potiguara | Potyguara | Unclassified | | 11,424 | – | extinct | Brazil | |
| Tapeba | Tapebano, Perna-de-Pau | Unclassified | | 5,741 (2006) | – | extinct | Brazil | |
| Tingui-Botó | | Unclassified | | 302 | – | extinct | Brazil | |
| Tremembé | | Unclassified | | 2,049 (2006) | – | extinct | Brazil | |
| Truká | | Unclassified | | 4,169 (2006) | – | extinct | Brazil | |
| Wassú | | Unclassified | | 1,560 (2003) | – | extinct | Brazil | |
| Xokó | Chocó | Unclassified | | 364 (2006) | – | extinct | Brazil | |
| Kariri-Xocó | | Unclassified | | 1,763 (2000) | – | extinct | Brazil | |
| Xukuru-Kariri | | Unclassified | | 2,652 (2006) | – | extinct | Brazil | |
| Xukuru | | Unclassified | | 9,064 (2006) | – | extinct (early 1960s) | Brazil | |
| Huilliche | Chesungun | Araucanian | | 2,000 (1982) | few elders | moribund | Chile | |
| Mapudungun | Mapuche | Araucanian | | 604,349 | 250,000 | endangered | Chile | Argentina |
| Aymara | | Aymaran | | 48,501 | 24,000 | endangered | Chile | Bolivia, Peru, Argentina |
| Selkʼnam | Ona | Chonan | | – | – | extinct | Chile | Argentina † |
| Quechua | | Quechuan | | 6,175 | 1,000 ? | endangered | Chile | Argentina, Bolivia, Peru, Ecuador, Colombia |
| Kunza | Atacameño, Likan Antai, Ulipe, Lipe | Isolate | | 21,015 | – | extinct (1960) | Chile | Argentina †, Bolivia † |
| Yahgan | Yámana, Háusi Kútə | Isolate | | 1685 / 70 | 1 | moribund | Chile | Argentina † |
| Kawésqar | Qawasqar, Alacaluf | Isolate | | 2622 / 101 | 20 | moribund | Chile | |
| Achagua | | Arawakan | | 283 (2001) | 283 | seriously endangered | Colombia | Venezuela † |
| Baniva | Baniva del Guainía | Arawakan | | ? | few? | seriously endangered | Colombia | Venezuela, Brazil |
| Cabiyarí | Kabiyari, Kawiyarí, Kawiri, Cauyari, Cabuyari | Arawakan | | 311 (2001) | 311 | seriously endangered | Colombia | |
| Curripaco | Curripaco-Baniva, Kurripako, Baniva del Isana | Arawakan | | 7,827 (2001) | 7,000? | potentially endangered | Colombia | Venezuela, Brazil |
| Wayuunaiki | Guajiro, Goajiro | Arawakan | | 149,827 (2001) | 149,827 | potentially endangered | Colombia | Venezuela |
| Piapoco | Piapoko, Tsáçe | Arawakan | | 4,926 (2001) | 4,926 | potentially endangered | Colombia | Venezuela |
| Tariana | Tariano | Arawakan | | 445 (2001) | 0? | possibly extinct | Colombia | Brazil |
| Yucuna-Matapí | Yukuna | Arawakan | | 770 (221) | 770 | endangered | Colombia | Brazil? |
| Awa Pit | Awapit, Awá, Awa-Cuaiquer, Cuaiquer, Kwaiker | Barbacoan | | 15,364 (2001) | < 15,364 | endangered | Colombia | Ecuador |
| Guambiano | Coconuco, Guanaca | Barbacoan | | 23,462 (2001) | 23,462 | endangered | Colombia | |
| Totoró | | Barbacoan | | 4,130 (2001) | 4 | moribund | Colombia | |
| Carijona | Karijona, Tsahá | Cariban | | 307 (2001) | < 10 | moribund | Colombia | |
| Opón-Carare | | Cariban | | ? | – | extinct | Colombia | |
| Yuko | Yukpa, Yucpa, Japrería | Cariban | | 3,651 (2001) | 3,651 | potentially endangered | Colombia | Venezuela |
| Arhuaco | Ika, Ijka, Bíntukua | Chibchan | | 14,799 (2001) | 14,799 | potentially endangered | Colombia | |
| Barí | Motilón | Chibchan | | 3,617 (2001) | 3,617 | potentially endangered | Colombia | Venezuela |
| Chimila | Ette Taara | Chibchan | | 900 (2001) | 900 | endangered | Colombia | |
| Cuna | Kuna, Tule | Chibchan | | 1,231 (2001) | 1,231 | endangered | Colombia | PA |
| Damana | Sanka, Malayo, Arsario, Wiwa | Chibchan | | 1,922 (2001) | 1,922 | endangered | Colombia | |
| Kogui | Kawgian, Kággaba, Kogi | Chibchan | | 9,911 (2001) | 9,911 | potentially endangered | Colombia | |
| Uwa-Tunebo | Uw Kuwa, Uʼwa | Chibchan | | 7,231 (2001) | 7,231 | potentially endangered | Colombia | Venezuela † |
| Emberá | Pede Epenã, Epérã Pedée, Pede, Chamí, Catío, Katío, Sambú | Chocoan | | 88,747 (2001) | 88,747? | potentially endangered | Colombia | Ecuador, PA |
| Waunana | Waunán, Waunméu, Waumeo, Chocó, Noanama | Chocoan | | 8,177 | 8,177 | potentially endangered | Colombia | PA |
| Zenú | | Chocoan | | 34,566 | – | extinct | Colombia | |
| Cuiba | Cuiva, Kuiva | Guahiboan | | 2,445 (2001) | 2,445 | endangered | Colombia | Venezuela |
| Sikuani | Hiwi, Jive, Guahibo, Vichadeño, Amorúa, Tigrero | Guahiboan | | 23,006 (2001) | 23,006 | potentially endangered | Colombia | Venezuela |
| Guayabero | Mitua, Jiw | Guahiboan | | 1,118 (2001) | 1,118 | endangered | Colombia | |
| Hitnu | Jitnu, Macaguane-Hitnu | Guahiboan | | 441 (2001) | 441? | endangered | Colombia | |
| Pepojivi | Playero, Guahibo Playero | Guahiboan | | < 200 (1982) | < 200 | seriously endangered | Colombia | Venezuela |
| Hup | Hupda, Hupdë | Nadahup | | 235 | 235 | seriously endangered | Colombia | Brazil |
| Kakua | Cakua | Nadahup | | 220 | 220 | seriously endangered | Colombia | |
| Nukak | | Nadahup | | 390 | 390 | endangered | Colombia | |
| Yuhup | Yuhuo Makú | Nadahup | | 200 | 200 | seriously endangered | Colombia | Brazil |
| Yagua | Yawa | Peba-Yaguan | | 297 (2001) | 297 | endangered | Colombia | Peru |
| Inga | Ingano | Quechuan | | 19,079 (2001) | 8,000 | endangered | Colombia | |
| Piaroa | | Sáliba-Piaroan | | 773 (2001) | 773 | endangered | Colombia | Venezuela |
| Sáliba | Sáliva | Sáliba-Piaroan | | 1,929 (2001) | < 1,929 | endangered | Colombia | Venezuela |
| Bará | Waimaja, Waimasa, Waymasa, Waimaha, Barasano del Norte | Tucanoan | | 109 (2001) | 109 | seriously endangered | Colombia | Brazil |
| Barasana | Barasano, Barasano del Sur, Pãnerã, Banera Yae | Tucanoan | | 1,890 (1997) | 1,890 | endangered | Colombia | Brazil |
| Carapana | Karapana | Tucanoan | | 464 (2001) | 464 | endangered | Colombia | Brazil |
| Cubeo | Kubeo | Tucanoan | | 6,647 (2001) | 6,647 | potentially endangered | Colombia | Brazil |
| Desano | | Tucanoan | | 2,457 (2001) | 2,457 | endangered | Colombia | Brazil |
| Koreguaje | Coreguaje, Koʼreuaju | Tucanoan | | 2,212 (2001) | 2,212 | endangered | Colombia | |
| Macaguaje | Makaguaje | Tucanoan | | 50 (2001) | 0? | possibly extinct | Colombia | |
| Macuna | Makuna | Tucanoan | | 1,009 (2001) | 1,009 | endangered | Colombia | Brazil |
| Piratapuyo | Piratapuya | Tucanoan | | 630 (2001) | 630 | endangered | Colombia | Brazil |
| Pisamira | Pápiwa | Tucanoan | | 61 (2001) | 25 | seriously endangered | Colombia | Brazil |
| Siona | SionaSecoya | Tucanoan | | 734 (2001) | 500 (2003) | endangered | Colombia | Ecuador, Peru |
| Siriano | | Tucanoan | | 749 (2001) | 749 | endangered | Colombia | Brazil |
| Taiwano | Taibano, Eduria | Tucanoan | | 22 (2001) | 22 | moribund | Colombia | |
| Tanimuca-Letuama | Opaina, Ufaina, Retuarã | Tucanoan | | 1,952 (2001) | < 1,952 | endangered | Colombia | |
| Tatuyo | | Tucanoan | | 331 (2001) | 331 | endangered | Colombia | |
| Tucano | | Tucanoan | | 6,996 (2001) | 6,996 | potentially endangered | Colombia | Brazil |
| Tuyuca | | Tucanoan | | 642 (2001) | 642 | endangered | Colombia | Brazil |
| Wanano | Guanano, Kotiria | Tucanoan | | 1,395 (2001) | 1,395 | endangered | Colombia | Brazil |
| Yauna | | Tucanoan | | 103 (2001) | 103? | seriously endangered | Colombia | |
| Yurutí | | Tucanoan | | 687 (2001) | 687 | endangered | Colombia | Brazil |
| Cocama | Kokama, Cocama, Cocamilla | Tupían | Tupí-Guaranían | 792 (2001) | few semi-speakers | moribund | Colombia | Peru, Brazil |
| Nonuya | | Witotoan | Witotoan proper | 228 (2001) | 2 | moribund | Colombia | |
| Ocaina | | Witotoan | Witotoan proper | 137 | 137 | seriously endangered | Colombia | Peru |
| Witoto | Witoto, Witoto Murui, Witoto Mïnïca, Witoto Muinane | Witotoan | Witotoan proper | 7,343 | 7,343 | potentially endangered | Colombia | Peru, Brazil †? |
| Bora | | Witotoan | Boran | 701 (2001) | <500 | seriously endangered | Colombia | Peru |
| Miraña | | Witotoan | Boran | 715 (2001) | <100 | seriously endangered | Colombia | Brazil |
| Muinane | Bora Muinane | Witotoan | Boran | 547 | 50–100? | seriously endangered | Colombia | |
| Aʼingae | Cofán, Kofán | Isolate | | 1,143 (2000) | 379 (2008) | endangered | Colombia | Ecuador |
| Andoke | Andoque | Isolate | | 597 (2001) | 597 | endangered | Colombia | |
| Kamsá | Camsá, Kamëntsa | Isolate | | 4,773 (2001) | 4,773 | potentially endangered | Colombia | |
| Nasa Yuwe | Paéz | Isolate | | 138,501 (2001) | 60,000 | endangered | Colombia | |
| Ticuna | Tikuna | Isolate | | 7,102 (2001) | 7,102 | potentially endangered | Colombia | Peru, Brazil |
| Tinigua | | Isolate | | 1? | 1 (2008) | moribund | Colombia | |
| Carabayo | Yuri | Unclassified | | 217 (2001) | 217 | seriously endangered | Colombia | |
| Wãnsöhöt | Puinave | Unclassified | | 6,604 (2001) | 6,604 | potentially endangered | Colombia | Venezuela |
| Awapit | | Barbacoan | | 3,283 | 2,100 | endangered | Ecuador | Colombia |
| Chaʼpalaa | Chaʼpalaachi, Chachi, Cayapa | Barbacoan | | 5,465 | 5,871 | endangered | Ecuador | |
| Tsafiqui | Tsafiki, Tsáchila, Tsachela, Colorado | Barbacoan | | 1,484 | 1,872 | endangered | Ecuador | |
| Epera Pedede | Êpera, Epena Pedee, Siapedie, Emberá, Emberá del Sur, Emberá Chami | Chocoan | | 65 | 52 | seriously endangered | Ecuador | Colombia |
| Achuar-Shiwiara | Achiar Chicham | Jivaroan | | 2,404 | 2,943 | endangered | Ecuador | Peru |
| Shiwiar Chicham | | Jivaroan | | 612 | 579 | endangered | Ecuador | |
| Shuar | Chicham | Jivaroan | | 52,697 | 42,261 | potentially endangered | Ecuador | |
| Quichua | Cañar, Azuay, Cotopaxo, Tungurahua, Chimborazo, Imbabura, Loza, Napo, Pastaza, and Salasaca dialects | Quechuan | | 408,395 | 451,783 | potentially endangered | Ecuador | Argentina, Chile, Bolivia, Peru, Colombia |
| Secoya | Siona-Secoya, Pai Coca | Tucanoan | | 240 | 85 | seriously endangered | Ecuador | Colombia, Peru |
| Pai Coca | Siona, Kokakañú | Tucanoan | | 304 | 260 | seriously endangered | Ecuador | |
| Teteté | | Tucanoan | | ? | 2 (1969) | possibly extinct | Ecuador | |
| Záparo | Kayapi | Zaparoan | | 346 | 176 | seriously endangered | Ecuador | |
| Aʼingae | Cofán | Isolate | | 1,044 | 638 | endangered | Ecuador | Colombia |
| Huao | Wao, Waorani, Waotededo, Wao Tiriro, Auca, Sabela | Isolate | | 1,534 | 1,616 | endangered | Ecuador | |
| Lokono | Arawak | Arawakan | | 15,500 (2000) | 1,500 | seriously endangered | Guyana | Suriname, French Guiana, Venezuela |
| Wapishana | | Arawakan | | 6,900 (2000) | < 6,900 | endangered | Guyana | Brazil |
| Mawayana | | Arawakan | | ? | few rememberers | extinct | Guyana | Suriname, Brazil † |
| Akawayo | Kapon | Cariban | | 5,000 (2000) | < 5,000 | endangered | Guyana | Venezuela, Brazil |
| Arekuna | Pemon | Cariban | | 400–500 | 400–500 | endangered | Guyana | Venezuela, Brazil |
| Kariʼna | Carib | Cariban | | 3,000 (2000) | few hundred | seriously endangered | Guyana | French Guiana, Suriname, Venezuela, Brazil |
| Makushi | Pemon | Cariban | | 7,750 (2000) | < 7,750 | endangered | Guyana | Venezuela, Brazil |
| Patamona | Kapon | Cariban | | 5,000 (2000) | < 5,000 | endangered | Guyana | Venezuela, Brazil |
| Waiwai | | Cariban | | 240 | 240 | seriously endangered | Guyana | Brazil |
| Warao | | Isolate | | 5,000 (2000) | few | seriously endangered | Guyana | Venezuela, Brazil |
| Taruma | Saluma, Saloema, Charuma | Unclassified | | ? | few | moribund | Guyana | Suriname †, Brazil † |
| Lokono | Arawak | Arawakan | | 2,000 | 500-700 | endangered | Suriname | French Guiana, Guyana, Venezuela |
| Mawayana | | Arawakan | | 60-80 | < 5 | moribund | Suriname | |
| Akuriyo | | Cariban | | 40-50 | 3 | moribund | Suriname | |
| Kariʼna | Carib | Cariban | | 3,000 | 1,200 | seriously endangered | Suriname | Guyana, French Guiana, Venezuela, Brazil |
| Sikïiyana | | Cariban | | 60-70 | < 12 | moribund | Suriname | |
| Trio | | Cariban | | 1,300 | 1,300 | endangered | Suriname | Brazil |
| Tunayana | Katuena | Cariban | | 80-90 | 10 | moribund | Suriname | |
| Wayana | | Cariban | | 450 | 450 | endangered | Suriname | French Guiana, Brazil |
| Arawak | Lokono | Arawakan | | 1,500 | 375 | seriously endangered | French Guiana | Suriname, Guyana, Venezuela |
| Palikur | | Arawakan | | 1,500 | < 1500 | endangered | French Guiana | Brazil |
| Aparaí | | Cariban | | ? | few | seriously endangered | French Guiana | Brazil |
| Galibi | Kariʼna, Kaliʼna | Cariban | | 4,000 | 2,400 | endangered | French Guiana | Suriname, Guyana, Venezuela, Brazil |
| Wayana | | Cariban | | 1,000 | 1,000 | endangered | French Guiana | Suriname, Brazil |
| Emérillon | Teko | Tupían | Tupí-Guaranían | 400 | 400 | endangered | French Guiana | |
| Wayãpi | Wajãpi, Wayampi | Tupían | Tupí-Guaranían | 750 | 750 | endangered | French Guiana | Brazil |
| Angaité | | Enlhet-Enenlhet | | 3,730 | 1,030 | endangered | Paraguay | |
| Enlhet | Enlhet Norte, Enslet, Enthlit, Enlhet-Lengua, Lengua | Enlhet-Enenlhet | | 7,316 | 6,439 | endangered | Paraguay | |
| Enxet | Enxet Sur | Enlhet-Enenlhet | | 5,930 | 3,842 | endangered | Paraguay | |
| Guaná | Kashika | Enlhet-Enenlhet | | 258 | 29 | seriously endangered | Paraguay | |
| Sanapaná | Saʼapan, Kasnapan | Enlhet-Enenlhet | | 2,327 | 984 | endangered | Paraguay | |
| Toba-Enenlhet | including Toba-Maskoy | Enlhet-Enenlhet | | 1,509 | 1,253 | endangered | Paraguay | |
| Toba-Maskoy | | Enlhet-Enenlhet | | 764 | 12 | moribund | Paraguay | |
| Toba-Qom | Qom-Lik, Emok-Lik, Takshika, Toba in Argentina | Guaicuruan | | 1,499 | 1,183 | endangered | Paraguay | Argentina |
| Maká | Maca | Matacoan | | 1,307 | 1,042 | endangered | Paraguay | |
| Manjuy | Manjui, Chorote in Argentina; three varieties: Iyoʼwuhwa, Iyojwaʼja [Yohwaha], and Montaraz [Wikinawos, Manjuy] | Matacoan | | 452 | 365 | endangered | Paraguay | Argentina |
| Nivaclé | Nivaklé, Chulupí, Ashluslay | Matacoan | | 12,169 | 10,109 | endangered | Paraguay | Argentina |
| Aché | Axé, Aché-Guayaki, Guayakí | Tupían | Tupí-Guaranían | 1,242 | 911 | endangered | Paraguay | |
| Ava-Guaraní | Chiripá, Ava-Chiripá, Chiripá-Guaraní, Avakatu-ete, Ñandeva in Brazil | Tupían | Tupí-Guaranían | 13,872 | 6,308 | endangered | Paraguay | Brazil |
| Guaraní-Ñandeva | Ñandeva, Tapieté | Tupían | Tupí-Guaranían | 2,021 | 1,550 | endangered | Paraguay | Argentina, Bolivia |
| Guaraní Occidental | Ava-Guaraní in Argentina, Guaraní (Chiriguano) in Bolivia | Tupían | Tupí-Guaranían | 2,359 | 574 | seriously endangered | Paraguay | Argentina, Bolivia |
| Mbyá | | Tupían | Tupí-Guaranían | 14,624 | 10,016 | endangered | Paraguay | Argentina, Brazil |
| Pãi-Tavyterã | Kaiova, Kaiowa, Avá | Tupían | Tupí-Guaranían | 13,391 | 6,364 | endangered | Paraguay | Brazil |
| Ayoreo | Moro, Pyta Jovai | Zamucoan | | 2,100 | 1,756 | endangered | Paraguay | Bolivia |
| Chamacoco | Ishir, Yshyrö; 2 varieties: Ybytoso, Ybytoso | Zamucoan | | | | | Paraguay | |
| Ybytoso | | Zamucoan | | 1,553 | 1,174 | endangered | Paraguay | Brazil |
| Tamárâho | | Zamucoan | | 106 | 85 | endangered | Paraguay | Brazil |
| Madija | Madiha, Kulina, Kurina | Arawan | | 300 | 300 | endangered | Peru | Brazil |
| Asháninca | Asháninka | Arawakan | | 88,703 (2007) | 88,703 | potentially endangered | Peru | |
| Ashéninca | Ashéninka, Axininca, Ashéninca Pajonal | Arawakan | | 20,000 | 20,000 | potentially endangered | Peru | |
| Campa Caquinte | Poyenisati | Arawakan | | 500 | 500 | endangered | Peru | |
| Chamicuro | Chamekolo | Arawakan | | 126 (1993) | 8 (2008) | moribund | Peru | |
| Iñapari | | Arawakan | | 68 (1993) | 4 (1998) | moribund | Peru | |
| Machiguenga | Matsiguenga, Matsigenka, Niagantsi | Arawakan | | 8,679 (1993) | 5,000 | endangered | Peru | |
| Nanti | Cugapacori, Kugapakori | Arawakan | | 450 | 450 | endangered | Peru | |
| Nomatsiguenga | Inato, Inaʼo, Inthome, Intsome | Arawakan | | 5,531 (1993) | 5,531 | potentially endangered | Peru | |
| Resígaro | | Arawakan | | 14 (1993) | 2 | moribund | Peru | |
| Yanesha | Amuesha | Arawakan | | 10,000 | 8,000 | potentially endangered | Peru | |
| Yine | Piro, Apurinã, Yinerï Tokanï | Arawakan | | 2,553 (1993) | 2,553 | potentially endangered | Peru | |
| Aymara | | Aymaran | | 434,372 (2007) | < 434,372 | potentially endangered | Peru | |
| Cauqui | | Aymaran | | ? | 9 (2005) | moribund | Peru | |
| Jaqaru | or Cauqui | Aymaran | | 3,000? | 725? | endangered | Peru | |
| Shawi | Chayahuita | Cahuapanan | | 21,424 (2007) | 14,000 | endangered | Peru | |
| Shiwilu | Jebero, Xebero | Cahuapanan | | 642 (1993) | < 30 | seriously endangered | Peru | |
| Harakmbut | Harakmbut Hate, Harakmbut Ate, Amarakaeri | Harakmbut-Katukinan | | 1,206 (1993) | 1,206 | endangered | Peru | |
| Cholón | or Seeptsá | Hibitocholonan | | ? | 2 (1986) | possibly extinct | Peru | |
| Achuar-Shiwiar | Shiwiar-Maina | Jivaroan | | 2,500 (2008) | 2,500 | endangered | Peru | Ecuador |
| Awajún | Aguajún, Ahuajún, Aguaruna | Jivaroan | | 55,366 (2007) | 55,366 | potentially endangered | Peru | |
| Huambisa | | Jivaroan | | 8,000 | 8,000 | potentially endangered | Peru | |
| Amahuaca | Ameuhaque, Amaguaco | Pano-Tacanan | Panoan | 247 (1993) | 100? | seriously endangered | Peru | Brazil |
| Capanahua | Capabaquebo, Kapanawa, Capacho | Pano-Tacanan | Panoan | 275 (2006) | 100? | seriously endangered | Peru | |
| Cashibo-Cacataibo | Uni | Pano-Tacanan | Panoan | 2,191 (1993) | 2,191 | endangered | Peru | |
| Cashinahua | Caxinahua, Kaxinawa, Hantxa Kuin, | Pano-Tacanan | Panoan | 957 (1993) | 957 | endangered | Peru | Brazil |
| Matsés | Matsés-Mayoruna, Mayoruna | Pano-Tacanan | Panoan | 2,500 | 2,500 | endangered | Peru | Brazil |
| Nahua | Yura, Yora, Yurahahua | Pano-Tacanan | Panoan | 450 | 450 | endangered | Peru | Bolivia |
| Sharanahua | Marinahua, Mastanahua, Parquenahua | Pano-Tacanan | Panoan | 438 | <438 | endangered | Peru | Brazil |
| Shipibo-Konibo | Shipibo-Conibo, Shipibo | Pano-Tacanan | Panoan | 22,517 (2007) | 22,517 | endangered | Peru | |
| Wariapano | Huariapano, Panobo | Pano-Tacanan | Panoan | ? | – | probably extinct (1991) | Peru | |
| Yaminahua | | Pano-Tacanan | Panoan | 400 | 400 | endangered | Peru | Bolivia, Brazil |
| Ese Ejja | Huarayo, Guarayo, Chama | Pano-Tacanan | Tacanan | 782 (1993) | 782 | endangered | Peru | Bolivia |
| Yagua | Yawa, Iahua | Peba-Yaguan | | 5,000 | 4,000 | endangered | Peru | Colombia |
| Quechua | | Quechuan | | 3,262,137 (2007) | < 3,262,137 | potentially endangered | Peru | Ecuador, Bolivia, Chile, Argentina |
| Orejón | Maihuna, Coto, Payagua, Tutapi | Tucanoan | | 300 | 100 | seriously endangered | Peru | |
| Secoya | Siona-Secoya | Tucanoan | | 329 (1993) | 329 | endangered | Peru | Ecuador |
| Cocama-Cocamilla | Xibitoana, Huallaga, Pampadeque | Tupían | Tupí-Guaranían | 10,705 | 1,000 | seriously endangered | Peru | Colombia, Brazil |
| Omagua | | Tupían | Tupí-Guaranían | 630 (1976) | 2 (2010) | moribund | Peru | Brazil |
| Huitoto | Witoto | Witotoan | Witotoan proper | 3,000 | 1,000 | endangered | Peru | Colombia, Brazil †? |
| Ocaina | | Witotoan | Witotoan proper | 150 | 50 | seriously endangered | Peru | Colombia |
| Bora | | Witotoan | Boran | 3,000 | 2,000 | endangered | Peru | Colombia, Brazil |
| Andoa-Shimigae | | Zaparoan | | ? | 2 (2008) | moribund | Peru | Ecuador |
| Arabela | Chiripuno | Zaparoan | | 500 | 50 (2001) | seriously endangered | Peru | |
| Cahuarano | Cahuarana | Zaparoan | | ? | 5 (1975) | extinct | Peru | |
| Iquito | Amacacore, Quiturran, Puca-Uma | Zaparoan | | 500 | 25–50 | seriously endangered | Peru | |
| Candoshi | Candoshi-Shapra | Isolate | | 1,586 (1993) | 1,586 | endangered | Peru | |
| Munichi | Muniche | Isolate | | ? | 8 (2008) | moribund | Peru | |
| Ticuna | | Isolate | | 8,000 | 8,000 | potentially endangered | Peru | Brazil, Colombia |
| Urarina | Kacha Ere, Shimacu, Itucale, Cimarrón | Isolate | | 2,000 (2003) | 2,000 | potentially endangered | Peru | |
| Vacacocha | Aushiri | Isolate | | ? | 2? (2008) | moribund | Peru | |
| Aguano | | Unclassified (Arawakan)? | | | 40 families (1959) | extinct | Peru | |
| Culle | Culli | Unclassified | | – | – | extinct (1950s) | Peru | |
| Mashco | Mashco-Piro | Unclassified | | 200–600 | 200–600 | endangered | Peru | Brazil |
| Taushiro | Pinche | Unclassified | | 20 | 1 (2008) | moribund | Peru | |
| Achagua | | Arawakan | | – | – | extinct | Venezuela | Colombia |
| Añu | Paraujano | Arawakan | | 11,205 (2001) | 20 | seriously endangered | Venezuela | |
| Baniva | Baníwa, Banibo, Baniva-Yavitero, Baniva del Guainía | Arawakan | | 2,408 (2001) | 608 | endangered | Venezuela | Colombia, Brazil |
| Baré | | Arawakan | | 2,815 (2001) | 239 / few | moribund | Venezuela | Brazil |
| Kurripako | Curripaco, Wakuénai, Baniva-Kurripako, Baniwa del Isana | Arawakan | | 4,925 (2001) | 3,743 | potentially endangered | Venezuela | Colombia, Brazil |
| Lokono | Arhwak, Aruaco | Arawakan | | 428 (2001) | 130 | seriously endangered | Venezuela | French Guiana, Suriname, Guyana |
| Mandahuaca | Mandawaka | Arawakan | | ? | – | possibly extinct | Venezuela | Brazil |
| Piapoko | Piapoco, Tsáçe | Arawakan | | 1,939 (2001) | 1,745 | potentially endangered | Venezuela | Colombia |
| Warekena | Guarequena | Arawakan | | 513 (2001) | 160 | seriously endangered | Venezuela | Brazil |
| Wayuunaiki | Guajiro, Wayuu | Arawakan | | 293,777 (2001) | 293,777 | potentially endangered | Venezuela | Colombia |
| Yavitero | Baniva-Yavitero, Banibo | Arawakan | | ? | 1 (2000) | possibly extinct | Venezuela | |
| Akawayo | Kapon | Cariban | | 245 (2001) | 180 | endangered | Venezuela | Guyana, Brazil |
| Chaima | | Cariban | | 4,084 (2001) | 63 | seriously endangered | Venezuela | |
| Eʼñepa | Panare, Mapoyo | Cariban | | 4,269 (2001) | 4,184 | potentially endangered | Venezuela | |
| Kariña | Kariñá, Kariʼna, Galibi | Cariban | | 16,686 (2001) | < 5,000 | endangered | Venezuela | French Guiana, Suriname, Guyana |
| Kumanagoto | | Cariban | | 553 (2001) | 49 | seriously endangered | Venezuela | |
| Makushi | Macushi, Makuxi | Cariban | | 83 (2001) | not known | endangered | Venezuela | Guyana, Brazil |
| Mapoyo | Mapoio, Wánai | Cariban | | 365 (2001) | 12 | moribund | Venezuela | |
| Patamona | Kapón | Cariban | | 200 | 200? | endangered | Venezuela | Guyana, Brazil |
| Pemon | Arekuna, Taurepan(g), Kamarakoto | Cariban | | 27,157 (2001) | 23,083 | potentially endangered | Venezuela | Guyana, Brazil |
| Pémono | | Cariban | | ? | 1 | possibly extinct | Venezuela | |
| Piritugoto | | Cariban | | 236 (2001) | 50 | seriously endangered | Venezuela | |
| Yawarana | Yavarana, Yabarana | Cariban | | 292 (2001) | 151 | seriously endangered | Venezuela | |
| Yeꞌkuana | Yeʼkwana, Deʼkwana, Maquiritare, Maiongong | Cariban | | 6,523 (2001) | 6,200 | endangered | Venezuela | Brazil |
| Yukpa | Yucpa, Japrería | Cariban | | 7,522 (2001) | < 7,522 | potentially endangered | Venezuela | Colombia |
| Barí | Motilón | Chibchan | | 1,520 (1992) | 1,520 | endangered | Venezuela | Colombia |
| Tunebo | Uwa-Tunebo | Chibchan | | ? | ? | possibly extinct | Venezuela | Colombia |
| Kuiva | Cuiva, Cuiba | Guahiboan | | 454 (2001) | 440 | endangered | Venezuela | Colombia |
| Hiwi | Jivi, Guahibo, Sikuani | Guahiboan | | 14,750 (2001) | 12,000 | potentially endangered | Venezuela | Colombia |
| Pepojivi | Playero, Guahibo Playero | Guahiboan | | 200 | 200 | seriously endangered | Venezuela | Colombia |
| Mako | Wirú, Wirö | Sáliba-Piaroan | | 1,130 (2001) | most | endangered | Venezuela | |
| Piaroa | Wothüha, Wotjüja, Wuʼtjuja | Sáliba-Piaroan | | 14,494 (2001) | 13,000 | endangered | Venezuela | Colombia |
| Sáliba | Sáliva | Sáliba-Piaroan | | 265 (2001) | 36 | seriously endangered | Venezuela | Colombia |
| Yeral | Geral, Nheengatu, Ñengatú | Tupían | Tupí-Guaranían | 1,294 (2001) | 650 | endangered | Venezuela | Brazil |
| Ninam | Yanam | Yanomaman | | ? | ? | seriously endangered | Venezuela | Brazil |
| Sanïma | Sanema, Sanuma | Yanomaman | | 3,035 (2001) | 3,035 | potentially endangered | Venezuela | Brazil |
| Yanomae | Yanomam, Yanomamë, Yanomama | Yanomaman | | ? | ? | potentially endangered | Venezuela | Brazil |
| Yanomamï | Yanoamï, Yanoamae | Yanomaman | | 12,234 (2001) | 12,234 | potentially endangered | Venezuela | Brazil |
| Hodï | Hoti, Jodi, Ho | Isolate | | 767 (2001) | 767 | endangered | Venezuela | |
| Pumé | Yaruro | Isolate | | 8,222 | 7,400 | endangered | Venezuela | |
| Sapé | Kariana, Kaliana, Caliana | Isolate | | 20 (2008) | few elders | moribund | Venezuela | |
| Uruak | Arutani, Awake | Isolate | | 29 (2001) | 29 | seriously endangered | Venezuela | Brazil? |
| Warao | | Isolate | | 36,028 (2001) | 32,400 | potentially endangered | Venezuela | Guyana |
| Puinave | Wãnsöhöt | Unclassified | | 1,307 (2001) | 550 | endangered | Venezuela | Colombia |

## Languages by classification
### Jolkesky (2016)

Jolkesky (2016) lists 43 language families and 66 language isolates (and/or unclassified languages) in South America – a total of 109 independent families and isolates.$^{:783–806}$

#### Andoke-Urekena

* Andoke
* Urekena

#### Arawa

* Suruwaha
* Madi-Deni-Paumari
** Deni-Kulina: Deni; Kulina
** Madi-Arawa
*** Arawa †
*** Madi: Banawa; Jamamadi; Jarawara
** Paumari

#### Barbakoa

* Barbakoa, Southern
** Karanki †
** Kayapa
** Kijo †
** Tsafiki
* Barbakoa, Northern
** Kokonuko
*** Kokonuko †
*** Guambiano-Totoro: Guambiano; Totoro
** Pasto
*** Awa Pit
*** Barbakoa †
*** Pasto †
*** Sindagua †

#### Bora-Muinane

* Bora; Miraña
* Muinane

#### Chacha-Cholon-Hibito

* Chacha †
* Cholon
* Hibito †

#### Chapakura-Wañam

* Napeka
* Rokorona
* Chapakura-Kitemoka
** Chapakura †
** Kitemoka
* More-Tora
** More-Kuyubi
*** Kuyubi-Kumana: Kumana; Kuyubi
*** More
** Tora
** Kabixi
* Urupa-Wañam-Wari
** Urupa
*** Urupa
*** Yaru
** Wañam-Wari
*** Wañam
*** Wari-Win: Oro Eo; Oro Wari; Oro Win

#### Charrua

* Chana
* Guenoa †
* Minuan †

#### Chibcha

* Pech
* Votic
** Maleku
** Rama
** Wetar
* Isthmus
** Boruka-Talamanca
*** Boruka
*** Talamanca
**** Teribe
**** Bribri-Kabekar
***** Bribri
***** Kabekar
** Doraske-Changena
*** Changena †
*** Doraske
** Guaymi
*** Buglere
*** Ngäbe
** Kuna
*** Kuna Paya-Pukuro
*** Kuna San Blas
* Magdalena
** Barí
** Chimila
** Nutabe †
** Tunebo
** Muiska
*** Guane †
*** Muiska †
** Sierra de Santa Marta
*** Kaggaba
*** Wiwa-Ika
**** Ika
**** Kankuamo †
**** Wiwa
*** Tairona †

#### Choko

* Waunana
* Embera
** Embera, Southern: Embera Baudo; Embera Chami; Epena
** Embera, Northern: Embera Katio; Embera Darien

#### Chon

* Chon, Southern
** Haush †
** Selkʼnam
* Chon, Northern
** Tewelche
** Teushen †

#### Duho

* Tikuna-Yuri
** Karabayo
** Tikuna
** Yuri †
* Saliba-Hodi
** Hodi
** Saliba-Betoi
*** Betoi †
*** Saliba-Piaroa
**** Saliba
**** Piaroa-Mako
***** Ature †
***** Mako
***** Piaroa

#### Guahibo

* Guahibo, Nuclear
** Kuiba
** Sikuani
** Playero
* Guayabero
* Hitnü

#### Harakmbet-Katukina

* Amarakaeri; Arasaeri; Sapiteri; Wachipaeri
* Katukina-Katawixi
** Katawixi
** Kanamari; Katukina

#### Jaqi

* Aymara
* Jaqaru
** Jaqaru
** Kawki

#### Jirajara †

* Ayoman †
* Gayon †
* Jirajara †

#### Jivaro

* Aguaruna
* Palta †
* Jivaro, Nuclear
** Achuar-Shiwiar
** Wambisa
** Shuar

#### Karib

* Karib, Western †
** Karare †
** Opon †
* Karib, Central
** Apalai
** Hianakoto
*** Guake †
*** Hianakoto-Umawa †
*** Karihona
** Kariña
** Palmella †
** Tarano
*** Akurio
*** Tiriyo
** Wayana
* Karib, Southern
** Kuikuro
*** Kalapalo
*** Kuikuro
*** Matipu
*** Nahukwa
** Pekodi
*** Arara-Ikpeng
**** Arara
**** Ikpeng
*** Bakairi
** Pimenteira †
* Karib, Northern
** Parukoto
*** Kashuyana
*** Parukoto, Nuclear
**** Hishkaryana
**** Sikiana
**** Waiwai
** Purukoto
*** Kapong: Akawayo; Patamona
*** Makushi
*** Pemon: Arekuna; Ingariko; Kamarakoto; Taurepang
*** Purukoto
** Venezuela
*** De'kwana-Wayumara
**** De'kwana
**** Wayumara
*** Eñepa
*** Kumana
**** Chayma
**** Kumanagoto †
*** Mapoyo-Yabarana
**** Mapoyo
**** Pemono
**** Yabarana
*** Tamanaku †
*** Yao †
**** Tiverikoto †
**** Yao †
** Yawaperi-Paravilhana
*** Sapara-Paravilhana
**** Paravilhana
**** Sapara
*** Yawaperi
**** Bonari †
**** Waimiri-Atroari
** Yukpa-Japreria
*** Japreria
*** Yukpa

#### Kawapana

* Shawi
* Shiwilu

#### Kechua

* Kechua I
** Kechua Pacaraos
** Kechua I, Central
*** Wallaga
**** Kechua Ambo-Pasco
**** Kechua Cajatambo
**** Kechua Wallaga
**** Kechua Wamalies
**** Kechua Junin
**** Kechua Tusi Pasco
*** Wankay
**** Kechua Waylla Wanka
**** Kechua Jauja-Wanka
*** Waylay
**** Kechua Conchucos, Southern
**** Kechua Conchucos, Northern
**** Kechua Corongo
**** Kechua Waylas
**** Kechua Siwas
*** Yauyos
**** Kechua Yauyos
* Kechua II
** Kechua Chincha †
** Kechua Cusco, Classical †
** Kechua IIa
*** Kechua Cajamarca-Lambayeque
**** Kechua Cajamarca
**** Kechua Lambayeque
*** Kechua Laraos-Lincha
**** Kechua Laraos
**** Kechua Lincha
** Kechua IIb
*** Kechua Chachapoyas
*** Kechua San Martin
*** Kichua, Equatorial
**** Inga
**** Kichua Chimborazo
**** Kichua Imbabura
**** Kichua Kañar-Loja
**** Kichua Napo
**** Kichua Pastaza
**** Kichua Pichincha
**** Kichua Salasaca
**** Kichua Tena
** Kechua IIc
*** Kechua Ayacucho
*** Kechua Cusco-Boliviano
**** Kechua Apolo
**** Kechua Arequipa
**** Kechua Boliviano
**** Kechua Cusco, Modern
**** Kechua Puno
*** Kechua Santiagueño

#### Lengua-Maskoy

* Lengua: Enlhet; Enxet
* Maskoy
** Maskoy, Southern: Angaite; Sanapana
** Maskoy, Northern: Kaskiha; Maskoy

#### Macro-Arawak

* Kandoshi / Shapra
* Muniche
* Pukina †
* Arawak
** Yanesha
** Arawak, Western
*** Aguachile †
*** Chamikuro
*** Mamoré-Paraguai
**** Mamoré-Guaporé
***** Mojo-Paunaka
****** Mojo: Ignaciano; Trinitario
****** Paunaka
***** Baure-Paikoneka
****** Baure: Baure; Joaquiniano; Muxojeone †
****** Paikoneka †
**** Terena: Chane †; Guana †; Kinikinau; Terena
*** Negro-Putumayo
**** Jumana-Pase: Jumana †; Pase †
**** Kaishana †
**** Nawiki
***** Kabiyari
***** Karu-Tariana
****** Karu: Baniwa; Kuripako
****** Tariana
***** Mepuri †
***** Piapoko-Achagua: Achagua; Piapoko
***** Wainambu †
***** Warekena-Mandawaka: Warekena; Mandawaka †
***** Yukuna-Wainuma: Mariate †; Wainuma †; Yukuna
**** Resigaro
**** Wirina †
*** Orinoco
**** Yavitero-Baniva: Baniva; Yavitero †
**** Maipure †
*** Pre-Andine
**** Ashaninka-Nomatsigenga: Ashaninka
***** Ashaninka-Kakinte: Ashaninka
****** Ashaninka-Asheninka
******* Ashaninka
******* Asheninka: Asheninka Pajonal; Asheninka Perene; Asheninka Pichis; Asheninka Ucayali; Ashininka
****** Kakinte
***** Machiguenga-Nanti: Machiguenga; Nanti
***** Nomatsigenga
*** Purus
**** Apurinã
**** Iñapari
**** Piro-Manchineri: Kanamare †; Kuniba †; Manchineri; Mashko Piro; Yine
** Arawak, Eastern
*** Lower Amazon
**** Atlantic: Marawan †; Palikur
**** Guaporé-Tapajós
***** Saraveka †
***** Tapajós: Enawene-Nawe; Paresi
**** Xingu
***** Kustenau †
***** Waura-Mehinako: Mehinaku; Waura
***** Yawalapiti
**** Waraiku †
*** Solimões-Caribbean: Marawan †; Palikur
**** Marawa †
**** Caribbean
***** Kaketio †
***** Wayuu-Añun
****** Añun
****** Wayuu
***** Lokono-Iñeri
****** Iñeri: Garifuna; Kalhiphona †
****** Lokono
***** Shebayo †
***** Taino †
**** Negro-Branco
***** Arua †
***** Mainatari †
***** Negro
****** Bare-Guinao: Bare; Guinao †
****** Bawana-Kariai-Manao: Bawana †; Kariai †; Manao †
****** Yabaana †
***** Branco
****** Mawayana
****** Wapishana-Parawana: Aroaki †; Atorada; Parawana †; Wapishana

#### Macro-Mataguayo-Guaykuru

* Payagua †
* Guachi †
* Guaykuru
** Kadiweu
** Qom-Abipon
*** Abipon †
*** Qom
**** Qom, Southern: Mokovi
**** Qom, Northern: Pilaga; Toba
* Mataguayo
** Mataguayo, Western
*** Chorote: Chorote Iyojwa'ja; Chorote Iyo'wujwa
*** Wichi: Wichi Guisnay; Wichi Nokten; Wichi Vejoz
** Mataguayo, Eastern
*** Maka
*** Nivakle

#### Macro-Jê

* Borum
* Ofaye
* Rikbaktsa
* Yate
* Bororo
** Bororo
** Otuke †
** Umutina †
* Maxakali
** Malali †
** Maxakali-Pataxo
*** Maxakali
*** Pataxo †
* Kamakã †
** Masakara †
** Kamakã-Menien †
*** Kamakã †
*** Menien †
* Kariri †
** Dzubukua †
** Kipea †
** Xoko †
* Macro-Jê, Nuclear
** Besiro
** Jeoromitxi-Arikapu: Arikapu; Jeoromitxi
** Karaja: Javae; Karaja; Xambioa
** Jê
*** Jê, Central
**** Akroa †
**** Xakriaba †
**** Xavante
**** Xerente
**** Jeiko †
*** Jê, Southern
**** Ingain: Ingain †; Kimda †
**** Kaingang-Xokleng
***** Kaingang: Kaingang; Kaingang Paulista
***** Xokleng
*** Jê, Northern
**** Apinaje
**** Kayapo: Mẽbengokre; Xikrin
**** Panara
**** Suya-Tapayuna: Suya; Tapayuna
**** Timbira: Apãniekra; Kraho; Krẽje †; Krĩkati; Parkateje; Pykobje; Ramkokamekra

#### Mapudungun

* Mapudungun, Nuclear
** Mapudungun
** Pewenche
** Rankelche
* Mapudungun, Southern: Williche
* Mapudungun, Northern
** Pikunche †
** Chango †

#### Moseten-Tsimane

* Moseten
* Tsimane

#### Mura-Matanawi

* Matanawi †
* Mura-Pirahã
** Mura: Bohura †; Mura †
** Pirahã

#### Nambikwara

* Sabane
* Nambikwara, Northern
** Guaporé: Mamainde; Negarote; Tawende
** Roosevelt: Lakonde; Latunde; Tawande
* Nambikwara, Southern
** Alantesu: Alantesu; Hahãintesu; Waikisu; Wasusu
** Halotesu: Halotesu; Kithãulhu; Wakalitesu; Sawentesu
** Manduka: Hukuntesu; Niyahlosu; Siwaisu
** Sarare

#### Otomako-Taparita †

* Otomako †
* Taparita †

#### Pano-Takana

* Takana
** Ese Ejja
** Kavineña-Takana
*** Kavineña
*** Takana
**** Araona
**** Maropa
**** Takana
* Pano
** Pano, Northern
*** Kulina (Pano)
*** Korubo
*** Matis
*** Matses
*** Pisabo
** Pano, Nuclear
*** Kasharari
*** Pano, Western
**** Kashibo-Kakataibo: Kashibo; Kakataibo
**** Nokaman †
*** Pano, Central
**** Purus
***** Amawaka
***** Kashinawa
***** Yaminawa-Iskonawa-Marinawa: Iskonawa; Marinawa; Yaminawa; Yawanawa
**** Jurua
***** Kanamari (Pano)
***** Katukina (Pano)
***** Marubo
**** Nukini-Remo
***** Nukini
***** Remo
***** Poyanawa
**** Atsawaka †
***** Arazaeri †
***** Atsawaka †
***** Yamiaka †
**** Chakobo
***** Chakobo
***** Karipuna (Pano)
***** Pakawara
**** Shipibo-Kapanawa
***** Kapanawa
***** Shipibo-Wariapano: Sensi †; Wariapano; Shipibo

#### Peba-Yagua

* Peba †
** Peba †
** Yameo †
* Yagua

#### Puinave-Nadahup

* Nadahup
** Nadëb: Nadëb do Rio Negro; Nadëb do Roçado
** Hup-Dâw
*** Dâw
*** Hup
**** Hupda
**** Yuhup
* Puinave-Kak
** Puinave
** Kak
*** Kakwa
*** Nukak

#### Puri †

* Coroado †
* Puri †

#### Tallan †

* Katakaos †
* Kolan †

#### Timote-Kuika

* Kuika †
* Mukuchi †
* Timote †

#### Tinigua-Pamigua

* Pamigua †
* Tinigua

#### Tukano

* Tukano, Western
** Kueretu †
** Tukano, Western, Nuclear
*** Mai Huna
*** Koreguaje-Pioje
**** Koreguaje-Tama
***** Koreguaje
***** Tama †
**** Pioje
***** Makaguaje †
***** Sekoya
***** Siona
***** Tetete †
* Tukano, Eastern
** Tanimuka-Retuarã-Yahuna: Tanimuka; Retuarã; Yahuna
** Tukano, Eastern, West
*** Kubeo-Desano
**** Kubeo
**** Desano-Yupua
***** Desano-Siriano: Desano; Siriano
***** Yupua †
*** Makuna-Barasano-Eduria: Makuna; Barasano; Eduria
** Tukano, Eastern, East
*** Tukano-Tatuyo
**** Tukano
**** Tatuyo-Bara-Waimaha
***** Tatuyo
***** Bara-Waimaha: Bara; Waimaha
*** Tuyuka-Wanano
**** Wanano-Piratapuyu
***** Wanano
***** Piratapuyo
**** Tuyuka-Karapanã
***** Karapanã-Pisamira: Karapanã; Pisamira
***** Tuyuka-Yuruti: Tuyuka; Yuruti

#### Tupi

* Arikem
** Arikem †
** Karitiana
* Monde
** Paiter
** Monde, Nuclear
*** Monde
*** Cinta-Larga-Zoro
**** Arua
**** Cinta-Larga
**** Gavião-Zoro: Gavião; Zoro
* Ramarama-Purubora
** Purubora
** Ramarama: Karo; Urumi
* Tupari
** Makurap
** Tupari, Nuclear
*** Sakurabiat-Akuntsu
**** Akuntsu
**** Sakurabiat
*** Kepkiriwat †
*** Tupari
*** Wayoro
* Tupi, Nuclear
** Juruna
*** Juruna
*** Manitsawa †
*** Shipaya
** Munduruku
*** Kuruaya
*** Munduruku
** Mawe-Aweti-Tupi-Guarani
*** Satere-Mawe
*** Aweti-Tupi-Guarani
**** Aweti
**** Tupi-Guarani
***** Kamayura
***** Kaapor-Ava
****** Ava-Canoeiro
****** Kaapor: Anambe †; Aura; Guaja; Takuñape †; Urubu-Kaapor
***** Akwawa-Arawete
****** Akwawa-Tapirape
******* Akwawa: Asurini do Tocantins; Parakanã; Surui (Tupi-Guarani)
******* Tapirape
****** Arawete-Asurini
******* Arawete: Amanaye †; Anambe; Ararandewara †; Arawete
******* Asurini do Xingu
***** Tupi-Guarani, Nuclear
****** Tenetehara: Guajajara; Tembe; Turiwara †
****** Kawahib-Kayabi
******* Apiaka
******* Juma
******* Kayabi
******* Kawahib: Amondawa; Karipuna (Tupi); Parintintin; Piripkura; Tukumanfed †; Uruewauwau; Wirafed
****** Tupi-Guarani, Diasporic
******* Guarani-Guarayu-Siriono
******** Guarayu: Guarayu; Pauserna
******** Siriono: Siriono; Jora †; Yuki
******** Guarani
********* Ache
********* Guarani: Guarani, Classical †; Chiriguano; Chiripa
********* Central: Guarani Paraguaio
********* Western: Guarani Boliviano; Tapiete
********* Eastern: Kayowa; Mbya; Ñandeva; Pai Tavytera; Sheta
******* Tupinamba-Kokama
******** Kokama-Omagua: Kokama; Kokamilla; Omagua
******** Tupi: Tupi †; Tupi Austral †
******** Tupinamba: Nhengatu; Tupinamba †
******** Wayampi: Emerillon; Wayampi; Zo'e

#### Uru-Chipaya

* Chipaya
* Murato
* Uru / Uchumataqu

#### Warpe †

* Allentiak †
* Millkayak †

#### Witoto-Okaina

* Okaina: Okaina
* Witoto
** Witoto Nüpode
** Minika-Murui
*** Witoto-Minika
*** Witoto-Murui
** Nonuya

#### Yanomami

* Sanuma
* Yanam
* Yanomami, Central
** Yanomami-Yanomamï: Yanomam; Yanomamï
** Yaroame

#### Zamuko

* Ayoreo: Ayoreo; Zamuko †
* Chamakoko
** Tomaraho
** Ïbïtoso

#### Zaparo

* Zaparo, Western
** Arabela
** Zaparo
* Zaparo, Eastern
** Kawarano
** Ikito

#### Isolates

* Aikanã
* Andaki †
* Arara do Rio Branco
* Arutani
* Atakame †
* Atikum †
* Aushiri †
* Chono †
* Guamo †
* Guato
* Gününa Këna
* Iranche/Myky
* Itonama
* Kakan †
* Kamsa
* Kañari †
* Kanichana
* Kanoe
* Kawesqar
* Kayuvava
* Kerandi †
* Kimbaya †
* Kingnam †
* Kofan
* Komechingon †
* Koraveka †
* Kueva †
* Kulle †
* Kunza †
* Kuruminaka †
* Kwaza
* Leko
* Lule †
* Máku †
* Malibu †
* Mochika †
* Mokana †
* Morike †
* Movima
* Muzo-Kolima †
* Omurano
* Oti †
* Paez
* Panche †
* Pijao †
* Puruha †
* Sanaviron †
* Sape
* Sechura †
* Tarairiu †
* Taruma
* Taushiro
* Tekiraka
* Trumai
* Tuxa †
* Umbra
* Urarina
* Vilela
* Waorani
* Warao
* Xukuru †
* Yagan
* Yaruro
* Yurakare
* Yurumangui †
* Zenu †

### Campbell (2012)

Lyle Campbell (2012) proposed the following list of 53 uncontroversial indigenous language families and 55 isolates of South America – a total of 108 independent families and isolates.

#### Aikaná (Aikanã, Huarí, Warí, Masaká, Tubarão, Kasupá, Mundé, Corumbiara)

* (dialect: Masaká (Massaca, Massaka, Masáca))

#### Arawakan (Arahuacan, Maipurean, Maipuran)

* Northern Arawakan (Upper Amazon, Maritime, and Eastern branches)
** Upper Amazon branch
*** Western Nawiki sub-branch
**** Wainumá group
***** Wainumá † (Waima, Wainumi, Waiwana, Waipa, Yanuma)
***** Mariaté †
***** Anauyá †
**** Piapoco group
***** Achagua (Ajagua, Xagua)
***** Piapoco
***** Amarizana †
**** Cabiyarí (Caviyarí, Kaviyarí, Cabiuarí, Cauyarí, Cuyare)
**** Warekena group
***** Guarequena (Warekena, Guarenquena, Arequena)
***** Mandahuaca (Mandawaka, Mandauaca, Maldavaca, Ihini, Arihini, Maldavaca, Cunipusana, Yavita, Mitua)
**** Río Negro group †
***** Jumana †
***** Pasé †
***** Kawishana † (Cawishana, Kaiwishana, Kayuwishana)
**** Yucuna (Jukuna) (dialects or languages)
***** Yucuna (Chucuna, Matapí) (Jukuna)
***** Garú † (Guarú)
*** Eastern Nawiki sub-branch
**** Tariana (Tariano, Tarîna, Taliáseri)
**** Karu (dialects or languages)
**** Ipeka-Kurripako (dialects or language)
**** Karútana-Baniwa (Baniva) dialect group
**** Katapolítani-Moriwene-Mapanai (dialects or language)
**** Resígaro
*** Central Upper Amazon sub-branch
**** Baré group
***** Marawá †
***** Baré (Bare, Ihini, Barawana, Barauna, Barauana, Arihini, Maldavaca, Cunipusana, Yavita, Mitua), Guinao † (Guinaú) (Aikhenvald (1999a: 71) mentions Guinau with Bare.)
**** Yavitero group
***** Yavitero † (Yavitano)
***** Baniva †
***** Maipure † (Aikhenvald (1999a: 71) gives Yavitero and Baniwa of Yavita as alternative names for a single language.)
**** Manao group
***** Manao †
***** Kariaí †
*** Arawakan Upper-Amazon branch languages of uncertain grouping
**** Waraikú †
**** Yabaána † (Jabaana, Yabarana)
**** Wiriná †
**** Xiriâna † (Shiriana)
** Maritime branch (Caribbean)
*** Aruán † (Aruá, Aroã)
*** Mawayana (Mahuayana, Mapidian)
*** Wapixana (Wapishana, Wapixiána, Wapisiana, Uapixana, Vapidiana) (dialects or languages) (dialects: Amariba, Atorai)
*** Ta-Maipurean sub-branch
**** Taíno †
**** Guajiro group
***** Guajiro (Goahiro, Goajiro, Guajira, Wayuunaiki, Wayuu)
***** Paraujano (Añún) (dialects: Alile, Toa)
***** Arawak (Locono, Lokono, Aruak, Arowak)
***** Iñeri (Igneri, Island Carib) (dialects or languages)
***** Kalhíphona † (Island Carib)
***** Garífuna (Black Carib)
** Eastern branch
*** Palikur (Palikour, Palicur, Palijur) (dialects or languages)
*** Marawán-Karipurá †
* Southern division
** Western branch
*** Amuesha (Amuese, Amoesha, Amueixa, Amoishe, Amagues, Amage, Omage, Amajo, Lorenzo, Amuetamo, Amaje, Yanesha)
*** Chamicuro (Chamicura, Chamicolo)
** Central branch
*** Paresí group
**** Paresí (Parecís, Paretí, Haliti)
**** Saraveca † (Sarave)
*** Waurá group
**** Waurá-Meinaku (Uara, Aura, Mahinacu)
**** Yawalapití (Jaulapiti, Yaulapiti)
**** Custenau † (Kustenau)
** Southern Outlier branch
*** Terena (Tereno, Terêna, Etelena, Guaná, Chané, Kinikinao) (dialects: Kinikanao, Etelena (Terena), Guaná)
*** Mojo group
**** Mojo (Morocosi, Mojeño, Moxeño, Moxo) (dialects or languages)
**** Ignaciano
**** Trinitario (dialects: Loreto (Loretano), Javierano)
**** Bauré (Chiquimiti, Joaquiniano may be a dialect of Bauré)
**** Paunaca (Pauna-Paicone (Paiconeca))
*** Piro group
**** Piro (dialects: Chontaquiro, Maniteneri, Maxineri)
**** Iñapari (Inamarí) (dialects: Inapari/Inamarí, Cuchitineri (Kushitineri), Cuniba)
**** Kanamaré † (Canamaré)
**** Apuriná (Apurinã, Ipuriná, Kangite (Cangaiti), Popengare)
** Campa branch (Campa dialects or languages)
*** Ashéninka (Ashéninga)
*** Asháninka (Asháninga)
*** Caquinte (Kakinte)
*** Pajonal Ashéninka (Pajonal Campa)
*** Machiguenga (Matsiguenga, Matsigenka) (dialects: Caquinte (Poyenisate), Nomatsiguenga (Atiri), Machiguenga)
*** Nomatsigenga
*** Nanti
* Other Arawakan languages too scantily known to determine to which branch of the family they belong:
** Cumeral (Ethnologue)
** Shebaya † (Shebayo, Shebaye) (David Payne 1991: 366–367)
** Lapachu (Apolista, Aguachile)
** Morique † (Morike)
** Ponares (Ethnologue)
** Omejes (Ethnologue)
** Salumã (Rodrigues 1986: 72)
** Tomedes (Tamudes)

#### Arawan (Arauán, Arahuan, Arawa)

* Paumarí (Purupurú, Pamarí, Palmarí, Curucuru) (dialects: Kurukuru, Uaiai, Paumarí (Pammari))
* Madi (Jarawara (Jarauára, Jaruára), Jamamadi, Banawá (Banivá, Baniwá-Jafí, Kitiya, Banavá, Banauá, Jafí))
* Zuruahá (Suruahá, Sorowahá)
* Dení-Kulina
** Dení (dialect: Inauini)
** Culina (Kulína; Madihá, Madija, Corina)
* Arawá † (Arua, Arauan)

#### Atacameño † (Cunza, Kunza, Atacama, Lipe Lican Antai)

* (local varieties: Apatama, Casabindo, Churumata, Cochinoca)

#### Aymaran (Jaqi, Aru)

* Southern Aymara
* Central Aymara (Tupe branch) (dialects: Jaqaru and Cauqui (Kawki))

#### Barbacoan

* Northern group
** Awan (Awa)
*** Awa Pit (Cuaiquer, Coaiquer, Kwaiker, Awa)
*** Pasto-Muellama
**** Muellama † (Muellamués)
**** Pasto †
** Coconucan (Guambiano-Totoró)
*** Guambiano (Mogües, Moguez, Moguex, Wam, Misak, Guambiano-Moguez, Namdrik)
** Totoró (Totoro, Polindara)
** Coconuco † (Kokonuko, Cauca, Wanaka)
* Southern group
** Chaʼpalaachi (Cayapa, Chachi, Nigua)
** Tsafiki (Colorado, Colima, Campaz, Tsáchela, Tsachila, Tsafiqui)

#### Extinct

    Barbacoa; Cara (Kara, Caranqui, Karanki, Imbaya); Pasto (Muellamués (Muellama)), Sindagua (Malla), and Coconuco

#### Betoi † (Betoy, Jirarra, Jirarru)

* (dialects: Airico, Betoi, Ele, Jirara, Lolaca, Situfa)

#### Boran (Bora-Muinane)

* Bora (Boro, Meamuyna; Miriña/Miranha)
* Muinane (Muinane Bora, Muinani, Muename)

#### Bororoan

* Eastern Bororo (Bororo proper, Boe)
* Western Bororo
* Umutina † (Umotina, Barbado)
* Otuque † (Otuké, Otuqui, Louxiru) (dialects: Coraveca (Corave, Curave, Ecorabe), Curuminaca, Curumina, Curucaneca, Curucane, Tapii)

#### Cahuapanan (Jebero, Kawapanan, Kahuapanan; earlier called Maina, Mainan)

* Cahuapana † (Cuncho, Chuncho, Concho, Chonzo)
* Chayahuita (Chawi, Chayabita, Chayhuita, Balsopuertino, Paranapura, Cahuapa; Chayawita, Tshaahui, Tsaawí, Chayabita, Shayabit, Balsapuertino; Paranapura)
* Jebero (Xebero, Chebero, Xihuila, Shiwilu)

#### Cañar-Puruhá †

* Cañar † (Cañari)
* Puruhá † (Puruguay)

#### Candoshi (Candoxi, Maina, Kandoshi, Shapra, Murato, Roamaina)

* (dialects: Shapra (Chapara), Kandoshi)

#### Cariban

* Venezuelan branch (Gildea 2003)
** Pemóng-Panare macro-group
*** Pemóng group (Kapóng, (Akawaio, Patamuna, Ingarikó), Makushi, Pemón (Taurepang, Kamarakóto, Arekuna))
*** Panare
** Mapoyo-Tamanaku macro-group
*** Mapoyo/Yawarana (Mapoyo, Wanai, Yawarana, Pémono)
*** Tamanaku †
** Pekodian branch
*** Bakairí
*** Arara group: Arara (Parirí), Ikpéng (Txikão)
* Subgroups not yet classified in possible larger subgroups in the family:
** Kumaná † (Chaima †, Cumanagota †)
** Makiritare (De'kwana, Ye'kwana, Maiongong)
** Nahukwa group: Kuikúru, Kalapalo
** Parukotoan group
*** Katxúyana (Kaxuiâna, Shikuyana, Warikyana)
*** Waiwai subgroup: Waiwai (Wabui, Tunayana), Hixkaryana
** Taranoan group
*** Tiriyo subgroup: Akuriyo, Tiriyo, Trio
*** Karihona (Carijona)
** Yukpa group: Yukpa, Japréria
* Languages not yet classified within possible subgroups:
** Apalaí
** Kari'nja (Carib, Kalinya, Cariña, Galibi)
** Waimirí Atroarí
** Wayana

#### Chapacuran (Chapakuran, Txapakuran)

* Itene group (Central Chapacuran)
** Wanham (Wañam, Wanyam, Huanyam)
** Kumaná (Torá, Toraz, Cumana, Cautario) (Abitana-Kumaná)
** Kabixí (Cabishi, Cabichí, Habishi, Parecís, Pawumwa)
** Itene (Iteneo, Iténez, Moré)
* Wari group (Southern Chapacuran)
** Quitemo † (Quitemoca) (Kitemo-Nape)
** Chapacura † (Huachi, Wachi, Tapacura, Chapakura)
** Urupá-Jarú (Txapakura; Yaru, Jaru, Ituarupa)
** Orowari (Pakaás-novos, Pacasnovas, Pacaha-novo, Uariwayo, Uomo, Jaru, Oro Wari)
** Oro Win

#### Charrúan †

* Charrúa †
* Güenoa † (Minuane)
* Chaná †

#### Chibchan

* Paya (Pech)
* Core Chibchan
** Votic
*** Rama (Melchora, Voto, Boto, Arama, Arrama)
*** Guatuso (Malecu)
** Isthmic
*** Western Isthmic
**** Viceitic
***** Cabécar (Chirripó, Tucurrique, Estrella)
***** Bribri (Viceíta)
**** Teribe (Térraba, Tiribí, Tirub)
**** Boruca † (Brunca)
*** Doracic
**** Dorasque † (Chumulu, Gualaca)
**** Chánguena † (Chánguina, Chánguene)
*** Eastern Isthmic
**** Guaymíic
***** Movere (Move, Guaymí, Penonomeño, Ngawbere/Ngäbere) (dialects: Inland Bocas del Toro, Coastal Bocas del Toro, Chiriquí)
***** Bocotá (Murire, Muoi, Guaymí Sabanero, Movere Sabanero)
**** Cuna (Cueva, Paya-Pocuro, Kuna)
** Magdalenic
*** Southern Magdalenic
**** Chibcha
***** Muisca † (Mosca, Chibcha)
***** Duit †
**** Tunebo (Uwa, Uw Cuwa; Tame, Sínsiga, Tegría, Pedraza) (dialects: Cobaría, Tegría, Agua Blanca, Barro Negro)
**** Barí (Motilón, Dobocubí, Cunaguasaya)
*** Northern Magdalenic
**** Arhuacic
***** Cogui (Cágaba, Kogi, Kogui, Coghui, Kagaba)
***** Eastern-Southern Arhuacic
***** Eastern Arhuacic
***** Damana (Guamaca, Sanká, Sanhá, Arsario, Malayo, Marocasero, Wiwa)
***** Kankuama (Atanques)
***** Ica (Bíntucua, Ika, Arhuaco, Bintuk)
***** Chimila (Chamila, Caca Weranos, San Jorge, Shimizya)
* Unclassified
** Huetar †
** Antioqueño † (two varieties: Nutabe and Catío (not to be confused with the Emberá (Chocoan) variety called Catío).

#### Chipaya-Uru (Uru-Chipaya, Uruquilla)

* Chipaya (erroneously earlier also called "Puquina")
* Uru (Uru of Iru-Itu, Uchumataqu, Iru-Wit'u, Uro)
* Chholo † (Murato)

#### Chiquitano (Besïro, Chiquito, Tarapecosi)

* (dialects: Besïro (Lomerío), Concepción, San Javier (Javierano), San Miguel, Santiago, Churapa, Sansimoniano, Tao)

#### Chocoan

* Waunana (Noanamá, Huaunana, Woun Meu, Waun Meo, Waumeo, Wounmeu, Wounaan, Noanama, Noenama, Nonama, Chocama, Chanco)
* Emberá dialect continuum (Catío, Chamí, Napipí River, Saija, Sambú)
** Southern Emberá
** Northern Emberá (Emperã, Eberã Bed'ea, Eperã Pedea, Atrato, Darién, Dariena, Panama Embera, Eberã, Cholo (Choco))

#### Cholonan † (Hibito-Cholon)

* Cholón † (Seeptsá, Tinganeses, Cholona)
* Híbito † (Hibito, Xibito, Xibita, Jibito, Chibito, Zibito, Ibito, Xibitoana)

#### Chonan (Tehuelchean, Chon family)

* Chonan proper
** Island Chonan
*** Selkʼnam † (Selknam, Shelknam, Ona, Aona)
*** Haush † (Manekenken)
** Continental Chonan
*** Tehuelche (Aoniken, Aonek'enk, Inaquen, Patagón)
*** Teushen † (Tehues, Patagón)
*** Patagón Costero †
* Gününa-Küne † (Gennaken, Northern Tehuelche, Puelche, Pampa, Gününa Yajich)

#### Guaicuruan (Waikuruan, Waykuruan)

* Kadiwéu (Caduveo, Mbayá, Ediu-Adig)
* Southern Guaicuruan
** Pilagá (Pilaca)
** Toba (Qom, Namqom)
** Mocoví (Mocobí)
** Abipón †

#### Guajiboan (Guahiboan)

* Guajibo (Guahibo, Guaybo, Sikuani, Sicuani, Guajibo, Goahibo, Guaigua, Guayba, Wahibo, Goahiva, Hiwi) (dialects: Guahibo (Sikuani), Amorua (Rio Tomo Guahibo), Tigrero)
* Cuiva (Cuiba, Cuiba-Wámonae) (dialects: Chiricoa, Masiware (Masiguare), Chiripo (Wupiwi, Siripu), Yarahuuraxi-Capanapara, Mayayero, Mochuelo-Casanare-Cuiba, Tampiwi (Mariposas), Amaruwa (Amorua), Mella, Ptamo, Sicuane (Sicuari))
* Churuya †
* Guayabero (Cunimía, Jiw, Mítus, Mítua)

#### Harákmbut-Katukinan

* Harákmbut (Harakmbet, Hate, Tuyoneri, "Mashco")
** (several dialects in two clusters: (1: Huachipaeri, Toyoeri (Tuyoneri, Tuyuneri); 2: Amaracaeri (Amarakaeri), Sapiteri, Arasaeri)
* Katukinan (Catuquinan)
** Katukina (Catuquina, Katukina do Jutaí) (dialect: Cutiadapa (Kutia-Dyapa))
** Dyapá (Southern Katukinan, Tshom-Djapá (Txunhuã-Djapá), Canamarí, Kanamarí) (perhaps the same as Tucundiapa (Tucano Dyapa, Hondiapa/Hon-Dyapá))
** Katawixí (Catawixi, Catauixi, Catawishi, Catauichi)

#### Huarpean † (Warpean)

* Huarpe † (Allentiac)
* Millcayac †

#### Irantxe (Iranxe, Iranche, Iranshe, Mynky, Münkü, Menki, Manoki, Myky)

* (dialects: Münkü (Mynky, Menku, Menkü, Myy), Irántxe))

#### Jabutían (Yabutían)

* Jabutí (Yabutí, Jabotí, Djeoromitxí, Kipiu, Quipiu)
* Arikapú (Maxubí, Aricapú)

#### Jêan (Gêan, Jê family)

* Northeastern Jê (Northern Jê)
** Timbíra (Canela (Kanela)), Krenjé, Krahó, Pykobyê)
** Kreen-Akarore (Ipewí, Kren-Akarore, Creen-Acarore, Panará)
** Apinajé (Apinayé)
** Kayapó (Cayapó, Kokairmoro) (dialects: Xikrin (Xukru, Diore), Kararaó, Kayapó-Kradaú)
** Suyá (dialects: Beiço de Pau (Tapayuna), Yaruma (Jarumá, Waiku))
* Central Jê (Akwe branch)
** Xavánte (Shavante, Chavante, A'uwe, A'we, Uptabi, Akuên, Akwen, Crisca, Pusciti, Tapacua)
** Akroá † (Akroá-Mirim, Acroá, Koroá, Coroá)
** Xerénte (Sherenté, Xerenti)
** Xakriabá † (Chicriaba, Chakriaba, Shacriaba, Chikriaba)
* Southern Jê
** Kaingang (Coroado, Coroados, Caingang, Bugre) (dialects: Paraná Kaingang, Central Kaingang, Southwest Kaingang, Southeast Kaingang)
** Xokléng (Shocleng, Aweikoma, Bugre, Botocudos)
** Ingáin † (Tains, Tain)
** Wayaná † (Guayaná, Guayana, Gualachí, Guanhanan)

#### Jirajaran †

* Jirajara †
* Ayomán † (Ayamán)
* Gayón † (Coyón)

#### Jivaroan

* Shuar (Jívaro, Maina, Jíbaro)
* Aguaruna (Aguajun, Ahuajun)
* Achuar (Achual, Achuar-Shiwiar)
* Huambisa

#### Kamakanan †

* Kamakán † (Camacán)
** Kamakán † (Kamakã, Camacán, Ezeshio)
** Mongoyó † (Mangaló, Monshoko)
** Kotoxó † (Kutaxó, Catashó, Cotoxó, Catathóy)
* Menién † (Manyã)
* Masakará † (Masacará)

#### Karajá (Caraja, Xambioá, Chamboa, Ynã, Karayá)

* Karajá-Xambioá † (Chamboa, Ynã)
* Javaé (Javaje, Javae)

#### Karirían † (Karirí family)

* Kipeá † (Karirí, Kirirí)
* Dzubukuá † (Kiriri, Dzubucua)
* Sabuyá † (Sapoyá)
* Kamurú † (Camurú, Pedra Branca)

#### Krenakan (Botocudoan, Aimoré language complex)

* Krenak (Botocudo, Aimoré, Nakrehé, Nakpié, Naknyanúk, Etwet, Minyãyirún, Yiporók, Pojitxá, Potén, Krekmún, Bakuén, Aranã, Batachoa, Crenaque)
* Guêren † (Guerén, Gren, Borun, Borúm)

#### Lule-Vilelan †

* Lule †
* Vilela †

#### Makúan (Makú family, Makú-Puinavean, Puinavean, Vaupés-Japura, Nadahup family, Guaviaré-Japurá family)

* Eastern Makúan
** Nadëb branch
*** Roçando Nadëb
*** Rio Negro Nadëb
** Dâw-Hupda-Yuhup
*** Dâw (Kamã, Kamã Makú, Kamarada, Makú-Kamarada)
*** Hupda-Yuhup
**** Hup (Hupda, Hupdë, Hupdá Makú, Macú de Tucano, Ubdé) (dialects: Hupdë, Tuhup, Nëhup)
**** Yuhup (Makú-Yahup, Yëhup, Yahup, Yahup Makú, "Maku")
* Western Makúan
** Kakua group
*** Kakua (Cacua, Bará, Macu de Cubeo, Macu de Guanano, Macu de Desano, Báda, Kákwa) (dialects: Vaupés Cacua, Macú-Paraná Cacua)
*** Nukak
** Puinave (Wonsüht, Wãnsöhöt)

#### Matacoan (Mataco-Mataguayan, Mataguayan)

* Chorote (Chorotí, Manjuy) (dialects: Iyo'wujwa, Yohwaha, Manjuy)
* Nivaclé (Niwaklé, Chulupí, Ashlushlay)
* Maká (Macá, Enimaca, Enimaga)
* Wichí (Mataco, Mataguayo, Weenhayek) (dialects: Nocten, Güisnay (Pilcomayo Wichí), Vejos (Vejoz, Aiyo, Hueshuo))

#### Maxakalían

* Maxakalí (Mashakali, Maxacari)
* Kapoxó † (Capoxo, Caposho)
* Monoxó † (Monoshó, Monachobm, Menacho)
* Makoní † (Maconí)
* Malalí †
* Pataxó † (Pataxó-Hanhanhain, Patasho)

#### Mosetenan (Mosetén-Chimane)

* Chimane (Chiman, Tsimane, Chumano, Nawazi-Moñtji)
* Mosetén (Rache, Muchan, Tucupi, Aparono)

#### Muran

* Mura †
* Pirahã (Pirahá)
* Bohurá † (Buxwaray)
* Yahahí †

#### Nambikwaran (Nambicuaran, Nambiquaran, Nambikuaran)

* Mamaindê (Northern Nambiquara, Mamande, Nakarothe) (dialects: Mamaindé, Negarotê, Tawanxte, Taxmainite, Taxwensite, Yalapmunxte (Lacondê, Latundê)
* Southern Nambikuaran
** Nambiquara (Nambikwara) (dialects: Manduka, Khithaulhu, Halotesu, Saxwentesu, Wakalitesu, Serra Azul, Hahaintesu, Wasusu, Alatesu, Waikisu, Galera)
** Kithãulhú (Southern Nambiquara) (dialect complex: Kabishi, Nambiquara, etc.)
** Sararé
* Sabané (Sabanés)

#### Otomacoan †

* Otomaco †
* Taparita †

#### Paezan

* Paez (Nasa Yuwe, Paisa)
* Paniquitá
* (?) Panzaleo † (Latacunga, Quito)

#### Pano-Takanan

* Panoan
** Mayoruna branch
*** Mayo group
**** Matses
**** Korubo (Chankuëshbo as co-dialect)
**** Dëmushbo
**** Kulina
*** Matis
** Mainline branch
*** Kasharari
** Core Mainline branch
*** Kashibo (Kakataibo as co-dialect)
*** Nawa group
**** Chakobo; (Pakawara as co-dialect)
**** Marubo subgroup
***** Marubo
***** Katukina
**** Poyanawa subgroup
***** Poyanawa
***** Iskonawa
***** Nukini
**** Shipibo (with Konibo and Kapanawa as co-dialects)
**** Headwaters subgroup
***** Kashinawa
***** Amawaka
***** Yaminawa (dialects: Sharanawa, Yawanawa, Shanenawa (Katukina de Feijó), Shawanawa (Arara), Mastanawa, Marinawa)
* Takanan
** Takana group
*** Tacana (Tupamasa)
*** Reyesano (San Borjano, Maropa)
*** Araona (Carina, Cavina)
*** Cavineña
** Chama group
*** Ese'ejja (Ese'eha, Ese Ejja, Ese Exa, Tiatinagua, Chama, Tambopata-Guarayo, Huarayo, Guacanawa, Chuncho, "Chama")
*** Toromona † (Toromono)

#### Purían † (Puri-Coroado)

* Purí † (Coroado)
* Koropó † (Coropa)

#### Qawasqaran (Alacalufan)

* Qawasqar (Northern Alacaluf, Alacaluf, Kaweskar, Kawésqar, Kawaskar, Aksánas) (dialects: Kawésqar, Tawókser)
* Alacaluf (Central Alacaluf, Hekaine)
* Southern Alacaluf (Halakwalup, Pecheré)

#### Quechuan

* Central Quechua (Huaihuash (Waywash)/Quechua I)
** Pacaraos Quechua
** Central Quechua
*** "Waylay" (Huailay, North)
**** Huaylas Quechua (Ancash Quechua)
**** Conchucos Quechua
** Ap-am-ah
*** Alto Pativilca
*** Alto Marañón
*** Alto Huallaga (Huánuco)
** "Wankay" (Huancay, South)
*** Yaru Quechua (Tarma, Junín)
*** Jauja-Huanca Quechua (Jauja, Huaycha Huanca, Huaylla Huanca (Huancayo))
*** Huangascar-Topará Quechua
* Peripheral Quechua (Huampuy/Quechua II)
** "Yungay" (Quechua IIA)
*** Central
**** Laraos
**** Lincha
**** Apurí
**** Chocos
**** Madeán
*** Northern
**** Cañaris-Incahuasi Quechua
**** Cajamarca Quechua
** "Chinchay" (Quechua IIB-C)
*** Northern
**** Chachapoyas Quechua (Amazonas Quechua)
**** San Martín Quechua
**** Loreto Quechua
**** Ecuador Quechua
*** Southern
**** Southern Peruvian Quechua
**** Ayacucho Quechua
**** Cuzco Quechua
**** Puno Quechua
**** Northern Bolivian Quechua
**** Southern Bolivian Quechua
**** Santiago del Estero Quichua ("Cusco")
**** Catamarca-La Rioja Quichua †

#### Sáliban (Sálivan, Sáliba-Piaroan)

* Sáliva (Sáliba)
* Piaroa (Piaroa-Maco, Wothüha, Guagua, Quaqua)
* Mako

#### Sechura-Catacaoan † (Sec)

* Sechura †
* Tallán † (Atalán)
** (varieties: Colán and Catacaos)

#### Tikuna-Yurí

* Tikuna (Ticuna, Tukuna, Tucuna)
* Yurí (Jurí, Yuri, Xurúpixuna)

#### Timotean † (Timote-Cuica)

* Timote-Cuica † (Miguri, Cuica)
* Mucuchí-Maripú † (Mocochí; Mirripú)

#### Tiniguan †

* Tinigua (Timigua)
* Pamigua (Pamiwa) †

#### Tukanoan (Tucanoan)

* Western Tukanoan
** Coreguaje (Koreguaje, Caquetá, Correguaje, Ko'reuaju, Chaocha Pai)
** Siona-Secoya
*** Macaguaje † (Makawahe, Piojé)
*** Secoya (Piohé, Siona-Secoya)
*** Siona
** Teteté † (Eteteguaje) (possibly a dialect of Siona)
** Orejón (Maijuna, Coto, Koto, Payoguaje, Payaguá, Payagua, Mai Ja, Oregon, Orechon, Tutapi) (dialect: Nebaji)
** Retuarã (Letuama, Tanimuca-Retuarã)
** Yahuna (Jaúna, Yauna)
** Tama †
* Eastern Tukanoan
** Cubeo (Kubeo, Pamié, Cuveo, Cubeu, Kobeua, Kobewa, Kubwa, Kobéwa, Hehenawa, Pamiwa)
** Miriti † (Miriti-Tapuyo, Neenoá)
** Macuna (Makuna, Buhagana, Baigana, Wuhána, Jepa-Matsi, Yepá-Mahsá, Yehpá Majsá, Yepá Maxsã, Yebamasã, Paneroa, Wahana, Makuna-Erulia)
** Yupuá-Duriña † (Yupua, Sokó, Uri, Duriña)
** Kueretú † (Cueretú, Coretú, Curetú)
** Desano-Siriano
** Bará-Tuyuka (Barasano, Tuyuca)
** Carapano (Karapaná, Karapano, Carapana-Tapuya, Tatuyo, Mochda, Moxdoa, Mextã)
** Tucano (Tukano, Dasea, Daxsea) (dialects: Yohoraa (Curaua), Wasona (Uasona))
** Wanano-Piratapuyo (Guanano, Wanâna, Uanana, Anana, Kótedia, Kótirya, Kotiria; Wanana, Waikena, Waikina, Uiquina, Waikino, Pira-Tapuya, Uaikena, Uaicana, Waikhara, Waina, Uaiana, Uainana, Urubu-Tapuya)
** Arapaso † (Arapaço, Arapasso, Koneá)

#### Tupían

* Western Tupían
** Arikém subfamily
*** Arikém (Ariquême)
*** Kabixiána
*** Karitiána (Caritiana)
** Mondéan subfamily
*** Paitér (Suruí, Suruí do Jiparaná, Suruí de Rondônia, Surui Paiter)
*** Cinta-larga
*** Gavião (Digüt, Ikõrõ, Gavião do Jiparaná)
*** Zoró
*** Mondé (Sanamaikã (Sanamaicá), Salamãi)
*** Aruá (Aruaxi, Aruashí)
** Puruborá (Boruborá, Puruba, Aurã, Pumbora, Puroborá, Burubora, Kuyubi, Cujubi, Migueleno, Miguelenho)
** Ramaráman subfamily
*** Káro (Arara, Urukú)
*** Ramaráma (Itogapúk, Ntogapíd)
*** Urumí
** Tuparían subfamily
*** Tuparí
*** Kepkiriwát (Quepiquiriuate, Kepikiriwat, Kepkeriwát)
*** Makuráp (Macurap, Macurape)
*** Mekéns (Mekém, Sakurabiat, Sakyrabiat)
*** Akuntsú (Akunsú)
*** Waratégaya (Amiapé)
*** Wayoró (Ayurú, Wayru, Wayurú, Ayurú, Ajurú, Uaiora, Wajaru)
*** Mekens
* Eastern Tupían
** Awetí (Auetö, Awetö, Aueto, Aueti, Auiti, Arauite, Arauine)
** Jurúnan subfamily
*** Jurúna (Yuruna, Yudjá, Djudjá, Jaruna)
*** Manitsawá (Maritsauá, Manitzula) (dialect: Arupai (Urupaya))
*** Xipáya (Shipaya, Shipaja, Xipaia)
*** Mawé (Maué, Sataré, Sateré, Sateré-Mawé)
** Mundurukún subfamily
*** Kuruáya (Caravare, Curuaia, Kuruaia)
*** Mundurukú (Mundurucu, Monjoroku, Weidyenye, Paiquize, Pari, Caras-Pretas)
** Tupí-Guaranían subfamily
*** Guaranían branch
**** Guaraní Antigo (Guaraní, old Guaraní)
**** Paraguayan Guaraní (Guaraní, Guarani paraguaio, Avañee)
**** Kaiwá (Kayowá, Kaiowá, Caiová, Caiguá, Pãi, Pãi-Tavyterã)
**** Nhandéva (Ñandeva, Chiripá)
**** Xetá (Shetá, Aré, Notobotocudo)
**** Chiriguano group (Ava, Simba, Chané, Izoceño (Isosó, Izozó), Tapiete)
**** Argentina, Bolívia, Paraguay (Dietrich 2007)
**** Guayakí (Guayaquí, Aché, Axe)
*** Guaráyoan branch
**** Guarayo (Guarayú)
**** Sirionó
**** Yúki (Yuqui)
*** Tupi branch of Tupí-Guaranían
**** Língua Geral Amazônica (Língua Geral, Nheengatú, Tapïhïya, Tupi moderno)
**** Língua Geral Paulista (Língua Geral, Tupí)
**** Tupí (Tupi antigo)
**** Tupinambá (Língua brasílica, Tupi antigo)
*** Teneteháran branch
**** Avá (Canoeiro, Avá-Canoeiro)
**** Tapirapé
**** Parakanã (Paracanã, Apiteréwa)
**** Tocantins Asuriní (Assurini, Asuriní do Tocantins, Asuriní do Trocará, Akwáwa)
**** Suruí (Suruí do Tocantins, Aikewara, Mudjetíre)
**** Tembé (Tenetehára)
**** Guajajára (Tenetehára)
**** Turiwára (Turiuara)
*** Xingu branch
**** Araweté
**** Amanajé (Amanage, Amanayé, Amanyé, Manajo, Manaxo, Manaze, Manazo)
**** Ararandewára
**** Aurê (Aurá)
**** Anambé of Cairarí
**** Xingu Asuriní (Assurini, Asuriní do Xingu, Asuriní do Coatinema, Awaeté)
*** Kawahíb branch
**** Amondáwa (Amundáwa)
**** Uruewawáu (Uru-eu-wau-wau, Uru-eu-uau-uau)
**** Karipúna
**** Piripkúra
**** Diahói (Diahui, Jahoi, Jahui, Diarrui)
**** Parintintín (Parintintim, Kagwahív)
**** Tenharín (Tenharim)
**** Tupí-Kawahíb (Tupi do Machado, Paranawát, Pawaté, Wiraféd)
***** Apiaká (Apiacá)
***** Júma (Yuma)
***** Kayabí (Caiabi)
*** Kamayurá (Kamaiurá, Camaiurá)
*** Northern Tupí-Guaranían branch
**** Anambé of Ehrenreich
**** Guajá (Awá, Avá, Awá Guajá, Ayaya, Guaxare, Wazaizara)
**** Ka'apór (Urubú, Urubú-Ka'apór, Kaapor)
**** Takunyapé (Taconhapé)
**** Wayampí (Oyampi, Wajãpi, Waiãpi)
**** Wayampipukú
**** Emérillon (Emerenhão, Emereñon, Emerilon, Melejo, Mereo, Mereyo, Teco)
**** Zo'é (Zoé, Jo'é)

#### Witotoan (Huitotoan)

* Ocaina (dialects: Dukaiya, Ibo'tsa)
* Early Huitoto
** Nipode (Huitoto Muinane, Nïpode, Nüpode Huitoto)
** Minica-Murai
*** Mɨnɨca (Huitoto Meneca)
*** Murui (Huitoto Murui, Murai, Búe)

#### Yaguan (Peban, Peba-Yaguan family)

* Yagua (Yihamwo, Nijyamïï, Nikyejaada, Yahua, Llagua, Yava, Yegua, Mishara)
* Peba † (Nijamvo)
* Yameo † (Llameo, Camuchivo, Masamae, Mazan, Parara)

#### Yanomaman (Yanomamian)

* Ninam (Yanam, Xirianá, Shiriana Casapare, Jawaperi, Crichana, Jawari)
* Sanumá (Sanimá, Sanma, Tsanuma, Guaika, Samatari, Samatali, Xamatari) (dialects: Ninam (Shirishana, Mukajai), Northern Ninam (Shiriana, Uraricaa-Paragua), Caura, Ervato-Ventuari, Auaris; Yanoma, Cobari (Kobali, Cobariwa))
* Yanomam (Waiká (Waicá), Yanomami, Yanomamé, Surara, Xurima, Parahuri, Yanoam)
** (dialects: Yanamam (Patimitheri, Waika), Yanomam (Naomam, Guadema, Wadema, Warema), Yanomay (Toototobi), Nanomam (Karime), Jauari (Joari, Yoari, Aica))
* Yanomamö (Yanomamï, Yamomame, Guaicá, Guaharibo, Guajaribo, Yanomami, Shamatri, Shaathari, Cobari Kobali, Cobariwa)
** (dialects: Eastern Yanomami (Parima), Western Yanomami (Padamo-Orinoco))

#### Zamucoan

* Ayoreo (Ayoré, Moro, Zamuco, Pyeta, Yovai)
** (dialect: Tsiricua, Tsiracua)
* Chamacoco (Ishiro, Jeywo)
** (dialects: Chamacoco Bravo (Tomaraho, Tomaraxa, Tumarahá), Ebitoso (Ebidoso, Ishiro))

#### Zaparoan

* Andoa † (Shimigae)
* Arabela
* Cahuarano †
* Iquito
* Záparo (Kayapi)
* Gae †
* Coronado †
* Oa †