# Jane Green (geneticist)

Professor Jane S. Green PhD, OC ONL, Hon FCCMG, FCAHS (born 1943) is a Canadian medical geneticist.
Jane S. Green is a well known Canadian medical geneticist who has been in the field for over 40 years, she has contributed and published to many papers, books and presentations with her peers and has been given many awards and recognitions because of it. Her research's in hereditary diseases, concentrating on hereditary cancers and eye disorders. Her extensive research has helped in identifying genetic mutations linked to hereditary cancers, ocular disorders, and syndromic conditions such as Bardet-Biedl syndrome and has shaped the future of medical genetics and Her work has helped the development of clinical and genetic screening programs, which allows for the faster identification and better treatment of hereditary diseases. Dr. green travels across NL to share her work with peers, patients, and families because she believes patient and family care is what's most important above all else.

## Career

Dr.Green studied Zoology, obtaining a BSc in 1964, and Drosophila Genetics, obtaining an MSc in 1966, both from the University of British Columbia. She moved to Newfoundland in 1967.
She helped to establish an Ocular Genetics Clinic from 1978 to 1986 and, after a family was referred there with Von Hippel–Lindau disease, began a cancer genetics screening programme.
She became a faculty member at Memorial University of Newfoundland in 1988 and obtained a PhD there in 1995; her dissertation was on the development of clinical and genetic screening programs for hereditary cancer syndromes. She was appointed Professor in the Discipline of Genetics there in 2002, and retired in April 2016.
She is also a Fellow of the Canadian Academy of Health Sciences (FCAHS).
| Year | Positions |
| 1978 -1988 | Research Assistant, Faculty of Medicine (Ocular Genetics) |
| 1991 – 1997 | Assistant Professor, Discipline of Medicine, Faculty of Medicine, Memorial University |
| 1996 – present | Consulting privileges as a Scientist, Non-Medical with the Newfoundland Cancer Treatment and Research Foundation |
| 1996 – present | Staff privileges as Scientist, Non-Medical, Department of Medicine, Eastern Health |
| 1997 – 2000 | Associate Professor with Tenure, Discipline of Medicine, Faculty of Medicine, Memorial University |
| 1988 – 1991 | Lecturer, Discipline of Medicine, Faculty of Medicine, Memorial University |
| 2000 – 2002 | Associate Professor, Discipline of Genetics |
| 2002 – 2016 | Professor, Discipline of Genetics, Faculty of Medicine, Memorial University |
| 2016 – present | Honorary Research Professor, Discipline of Genetics, Faculty of Medicine, Memorial University |

## Education

| Year | place | cerifcation |
| 1960 – 1964 | University of British Columbia | B.Sc. (Zoology) |
| 1964 – 1965 | University of British Columbia | M.Sc. (Genetics) |
| 1980 – 1981 | University of British Columbia and Vancouver General Hospital | (Research Year) |
| 1991 – 1995 | Memorial University | Ph.D. (Medical Genetics) |

## Contributions

Dr.Green as been credited in about 180+ works and some of her most recent ones are publicized in 2024-2025
| Year | Notable Publications |
| 1993 | Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer |
| 1993 | Genetic Mapping of a Locus Predisposing to Human Colorectal Cancer |
| 1960 | Report on the algorithmic language ALGOL 60 |
| 2004 | Comparative Genomics Identifies a Flagellar and Basal Body Proteome that Includes the BBS5 Human Disease Gene |
| 2007 | Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24 |
| 1994 | Replication Errors in Benign and Malignant Tumors from Hereditary Nonpolyposis Colorectal Cancer Patients |
| 1988 | Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma |
| 1989 | The Cardinal Manifestations of Bardet–Biedl Syndrome, a Form of Laurence–Moon–Biedl Syndrome |
| 2008 | The Clinical Phenotype of Lynch Syndrome Due to Germ-Line PMS2 Mutations |
| 1995 | Germline mutations in the von Hippel–Lindau disease tumor suppressor gene: Correlations with phenotype |
| 2007 | Founder and Recurrent CDH1 Mutations in Families With Hereditary Diffuse Gastric Cancer |
| 1997 | Germline Mutations of the MEN1 Gene in Familial Multiple Endocrine Neoplasia Type 1 and Related States |
| 1994 | hMSH2 Mutations in Hereditary Nonpolyposis Colorectal Cancer Kindreds |
| 2016 | Utility of whole-exome sequencing for those near the end of the diagnostic odyssey: time to address gaps in care |
| 1994 | Identification of intragenic mutations in the von Hippel-Lindau disease tumour suppressor gene and correlation with disease phenotype. |
| 2004 | Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome |
| 2005 | Clinical and genetic epidemiology of Bardet–Biedl syndrome in Newfoundland: A 22-year prospective, population-based, cohort study |
| 2000 | Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome |
| 2000 | Mutations in MKKS cause Bardet-Biedl syndrome |
| 1996 | Phenotypic expression in von Hippel-Lindau disease: correlations with germline VHL gene mutations. |

## Awards

List of all awards: Officer, Order of Canada; Member, Order of Newfoundland and Labrador; Fellow, Canadian Academy of Health Sciences; Honorary Member, Canadian College of Medical Geneticists; Founders Award, Canadian College of Medical Geneticists; CIHR Knowledge Translation Award; Community Service Award, NL Division, Canadian National Institute of the Blind.