# 2021 FINA World Swimming Championships (25 m) – Men's 4 × 50 metre medley relay

The Men's 4 × 50 metre medley relay competition of the 2021 FINA World Swimming Championships (25 m) was held on 20 December 2021.

## Records

Prior to the competition, the existing world and championship records were as follows.
| World record | Italy (ITA) | 1:30.14 | Kazan, Russia | 3 November 2021 |
| Competition record | Brazil (BRA) | 1:30.51 | Doha, Qatar | 4 December 2014 |
The following new records were set during this competition:
| Date | Event | Name | Nation | Time | Record |
| 20 December | Final | Kliment Kolesnikov (22.76) Kirill Strelnikov (25.62) Andrey Minakov (21.76) Vladimir Morozov (20.37) | Russian Swimming Federation | 1:30.51 | =CR |
| 20 December | Final | Shaine Casas (23.11) Nic Fink (25.13) Tom Shields (21.75) Ryan Held (20.52) | United States | 1:30.51 | =CR |

## Results
### Heats

The heats were started at 09:30.
| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| 1 | 1 | 4 | Russian Swimming Federation | Pavel Samusenko (23.38) Andrei Nikolaev (26.16) Oleg Kostin (22.08) Aleksandr Shchegolev (20.90) | 1:32.52 | Q |
| 2 | 1 | 6 | Egypt | Mohamed Samy (23.69) Youssef El-Kamash (26.40) Youssef Ramadan (22.37) Abdelrahman Sameh (20.73) | 1:33.19 | Q, AF |
| 3 | 2 | 7 | Brazil | Guilherme Guido (23.27) Caio Pumputis (26.33) Vinicius Lanza (22.51) Gabriel Santos (21.10) | 1:33.21 | Q |
| 4 | 1 | 8 | United States | Shaine Casas (23.34) Will Licon (26.11) Trenton Julian (22.57) Zach Apple (21.27) | 1:33.29 | Q |
| 5 | 2 | 4 | Italy | Lorenzo Mora (23.65) Nicolò Martinenghi (26.00) Michele Lamberti (22.84) Thomas Ceccon (21.11) | 1:33.60 | Q |
| 6 | 1 | 5 | Norway | Markus Lie (23.72) André Grindheim (27.30) Tomoe Hvas (22.49) Nicholas Lia (20.82) | 1:34.33 | Q |
| 7 | 1 | 3 | Poland | Kacper Stokowski (23.48) Marcin Cieślak (27.08) Jakub Majerski (22.63) Paweł Juraszek (21.35) | 1:34.54 | Q |
| 8 | 2 | 6 | Lithuania | Danas Rapšys (24.46) Andrius Šidlauskas (26.63) Deividas Margevičius (22.96) Simonas Bilis (21.15) | 1:35.20 | Q |
| 9 | 2 | 3 | France | Mewen Tomac (23.79) Antoine Viquerat (26.16) Thomas Piron (23.09) Yohann Ndoye Brouard (22.40) | 1:35.44 | |
| 10 | 2 | 5 | Turkey | Doruk Tekin (23.87) Berkay Ömer Öğretir (26.41) Rasim Oğulcan Gör (23.29) Baturalp Ünlü (22.05) | 1:35.62 | |
| 11 | 1 | 1 | Hong Kong | Lau Shiu Yue (24.41) Ng Yan Kin (27.62) Ng Cheuk Yin (23.32) Ian Ho (21.01) | 1:36.36 | NR |
| 12 | 1 | 7 | South Korea | Won Young-jun (24.04) Moon Jae-kwon (26.48) Moon Seung-woo (24.25) Lee Ho-joon (22.74) | 1:37.51 | |
| 13 | 1 | 2 | Vietnam | Trần Hưng Nguyên (25.00) Phạm Thanh Bảo (27.53) Hồ Nguyễn Duy Khoa (24.96) Nguyễn Hữu Kim Sơn (25.66) | 1:43.15 | |
| 14 | 2 | 2 | Kuwait | Faisal Al-Tannak (27.59) Ali Al-Zamil (29.45) Mashari Al-Samhan (25.51) Sauod Al-Shamroukh (24.23) | 1:46.78 | |
| | 2 | 8 | China | Wang Gukailai Qin Haiyang Sun Jiajun Wang Changhao | DSQ | |
| | 2 | 1 | Slovakia | | DNS | |

### Final

The final was held at 18:00.
| Rank | Lane | Nation | Swimmers | Time | Notes |
| | 4 | Russian Swimming Federation | Kliment Kolesnikov (22.76) Kirill Strelnikov (25.62) Andrey Minakov (21.76) Vladimir Morozov (20.37) | 1:30.51 | =CR |
| | 6 | United States | Shaine Casas (23.11) Nic Fink (25.13) Tom Shields (21.75) Ryan Held (20.52) | 1:30.51 | =CR, =AM |
| | 2 | Italy | Lorenzo Mora (23.24) Nicolò Martinenghi (25.30) Matteo Rivolta (21.95) Lorenzo Zazzeri (20.29) | 1:30.78 | |
| 4 | 3 | Brazil | Gabriel Fantoni (22.84) João Gomes Júnior (25.52) Vinicius Lanza (22.45) Gabriel Santos (21.10) | 1:31.91 | |
| 5 | 5 | Egypt | Mohamed Samy (23.68) Youssef El-Kamash (26.32) Youssef Ramadan (22.12) Abdelrahman Sameh (20.44) | 1:32.56 | AF |
| 6 | 1 | Poland | Kacper Stokowski (23.20) Marcin Cieślak (26.79) Jakub Majerski (22.45) Paweł Juraszek (20.69) | 1:33.13 | |
| 7 | 7 | Norway | Markus Lie (23.73) André Grindheim (27.08) Tomoe Hvas (22.41) Nicholas Lia (20.91) | 1:34.13 | |
| 8 | 8 | Lithuania | Danas Rapšys (24.40) Andrius Šidlauskas (26.58) Deividas Margevičius (22.77) Simonas Bilis (21.07) | 1:34.82 | |