# 2010 FINA World Swimming Championships (25 m) – Women's 4 × 100 metre medley relay

The Women's 4×100 Medley Relay at the 10th FINA World Swimming Championships (25m) was swum on 17 December 2010 in Dubai, United Arab Emirates. 21 nations swam in the preliminary heats, with the top-8 advancing to swim again in the final.

## Records

Prior to the competition, the existing world and championship records were as follows.
| | Name | Nation | Time | Location | Date |
| World record | Margaret Hoelzer (57.47) Jessica Hardy (1:03.58) Dana Vollmer (54.37) Amanda Weir (52.55) | United States | 3:47.97 | Manchester | 18 December 2009 |
| Championship record | Margaret Hoelzer (58.79) Jessica Hardy (1:03.98) Rachel Komisarz (55.93) Kara Denby (52.66) | United States | 3:51.36 | Manchester | 11 April 2008 |
The following records were established during the competition:
| Date | Round | Name | Nation | Time | WR | CR |
| 17 December 2010 | Heats | Gao Chang (56.41) Zhao Jin (1:04.72) Guo Fan (57.44) Li Zhesi (52.12) | China | 3:50.69 | | CR |
| 17 December 2010 | Final | Zhao Jing (56.52) Zhao Jin (1:04.20) Liu Zige (55.80) Tang Yi (51.77) | China | 3:48.29 | | CR |

## Results
### Heats

| Rank | Heat | Lane | Nation | Name | Time | Notes |
| 1 | 1 | 2 | China | Gao Chang (56.41) Zhao Jin (1:04.72) Guo Fan (57.44) Li Zhesi (52.12) | 3:50.69 | Q, CR |
| 2 | 2 | 4 | Australia | Rachel Goh (58.36) Sarah Katsoulis (1:05.50) Felicity Galvez (56.22) Emma McKeon (52.65) | 3:52.73 | Q |
| 3 | 3 | 4 | United States | Missy Franklin (58.38) Jessica Hardy (1:05.30) Christine Magnuson (56.44) Amanda Weir (53.54) | 3:53.66 | Q |
| 4 | 1 | 4 | Sweden | Michelle Coleman (59.58) Jennie Johansson (1:04.46) Petra Granlund (57.20) Claire Hedenskog (53.56) | 3:54.80 | Q |
| 5 | 2 | 3 | Canada | Sinead Russell (58.75) Martha McCabe (1:06.10) Katerine Savard (58.82) Geneviève Saumur (53.15) | 3:56.82 | Q |
| 6 | 3 | 3 | Russia | Kseniya Moskvina (58.86) Daria Deyeva (1:05.67) Svetlana Fedulova (59.28) Margarita Nesterova (53.30) | 3:57.11 | Q |
| 7 | 3 | 7 | Italy | Elena Gemo (59.04) Chiara Boggiatto (1:07.63) Caterina Giacchetti (59.03) Chiara Luccetti (53.57) | 3:59.27 | Q |
| 8 | 2 | 5 | Brazil | Fabíola Molina (58.48) Tatiane Sakemi (1:08.46) Daniele de Jesus (59.54) Tatiana Lemos (53.44) | 3:59.92 | Q |
| 9 | 3 | 6 | South Africa | Chanelle van Wyk (59.26) Katheryn Anne Meaklim (1:08.73) Mandy Loots (58.76) Leone Vorster (54.00) | 4:00.75 | |
| 10 | 3 | 1 | Norway | Katharina Stiberg (1:01.32) Sara Nordenstam (1:08.31) Ingvild Snildal (57.79) Cecilie Waage Johannessen (53.73) | 4:01.15 | |
| 11 | 3 | 5 | Japan | Miyuki Takemura (58.84) Rie Kaneto (1:08.41) Hiroko Sugino (58.22) Maiko Fujino (56.97) | 4:02.44 | |
| 12 | 1 | 1 | Turkey | Hazal Sarikaya (1:01.37) Dilara Buse Gunaydin (1:08.96) Iris Rosenberger (59.83) Burcu Dolunay (55.71) | 4:05.87 | |
| 13 | 1 | 6 | Chinese Taipei | Chen Ting (1:01.77) Chen I-Chuan (1:09.90) Cheng Wan-Jung (59.50) Ting Sheng-Yo (58.21) | 4:09.38 | |
| 14 | 2 | 6 | Venezuela | Jeserik Pinto (1:03.33) Daniela Victoria (1:11.10) Elimar Barrios (1:01.97) Ximena Vilar (57.08) | 4:13.48 | |
| 15 | 2 | 1 | Peru | Massie Milagros Carrillo (1:04.47) Patricia Quevedo (1:14.69) Oriele Alejandra Espinoza (1:02.49) Andrea Cedrón (59.98) | 4:21.63 | |
| 16 | 2 | 7 | Malta | Nicola Muscat (1:06.12) Melinda Sue Micallef (1:15.28) Davina Mangion (1:07.88) Talisa Pace (59.39) | 4:28.67 | |
| 17 | 3 | 2 | Macau | Vong Erica Man Wai (1:07.17) Lei On Kei (1:16.38) Ma Cheok Mei (1:05.18) Tan Chi Yan (1:01.50) | 4:30.23 | |
| – | 1 | 3 | Denmark | Pernille Jessing Larsen (1:01.76) Rikke Møller Pedersen Jeanette Ottesen Pernille Blume | DSQ | |
| – | 1 | 5 | Netherlands | | DNS | |
| – | 1 | 7 | Nigeria | | DNS | |
| – | 2 | 2 | Kenya | | DNS | |

### Final

| Rank | Lane | Nation | Name | Time | Notes |
| | 4 | China | Zhao Jing (56.52) Zhao Jin (1:04.20) Liu Zige (55.80) Tang Yi (51.77) | 3:48.29 | CR |
| | 3 | United States | Natalie Coughlin (56.83) Rebecca Soni (1:03.73) Dana Vollmer (55.62) Jessica Hardy (52.18) | 3:48.36 | |
| | 5 | Australia | Rachel Goh (57.39) Leisel Jones (1:03.76) Felicity Galvez (55.56) Marieke Guehrer (52.17) | 3:48.88 | |
| 4 | 7 | Russia | Anastasia Zuyeva (57.81) Yuliya Yefimova (1:04.23) Veronika Popova (57.79) Margarita Nesterova (53.25) | 3:53.08 | |
| 5 | 6 | Sweden | Petra Granlund (59.29) Joline Höstman (1:06.07) Therese Alshammar (55.88) Sarah Sjöström (52.74) | 3:53.98 | |
| 6 | 2 | Canada | Sinead Russell (58.47) Martha McCabe (1:07.00) Audrey Lacroix (58.25) Victoria Poon (52.85) | 3:56.57 | |
| 7 | 1 | Italy | Elena Gemo (58.65) Chiara Boggiatto (1:07.22) Caterina Giacchetti (58.30) Chiara Luccetti (53.41) | 3:57.58 | |
| 8 | 8 | Brazil | Fabíola Molina (58.45) Tatiane Sakemi (1:08.43) Daniele de Jesus (59.39) Tatiana Lemos (53.18) | 3:59.45 | |