OpenLLM-France/wikimedia huggingface dataset:
# Pharmacokinetics simulation

Pharmacokinetics simulation is a simulation method used in determining the safety levels of a drug during its development.

## Purpose

Pharmacokinetics simulation gives an insight to drug efficacy and safety before exposure of individuals to the new drug that might help to improve the design of a clinical trial. Pharmacokinetics simulations help in addition in therapy planning, to stay within the therapeutic range under various physiological and pathophysiological conditions, e.g., chronic kidney disease.

## Simulators

Simcyp Simulator and GastroPlus (from Simulations Plus) are simulators that take account for individual variabilities. PharmaCalc v02 and PharmaCalcCL allow to simulate individual plasma-concentration time curves based on (published) pharmacokinetic parameters such as half-life, volume of distribution etc.
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# Medullary cavity

The medullary cavity (medulla, innermost part) is the central cavity of bone shafts where red bone marrow and/or yellow bone marrow (adipose tissue) is stored; hence, the medullary cavity is also known as the marrow cavity.
Located in the main shaft of a long bone (diaphysis) (consisting mostly of compact bone), the medullary cavity has walls composed of spongy bone (cancellous bone) and is lined with a thin, vascular membrane (endosteum).
This area is involved in the formation of red blood cells and white blood cells, and the calcium supply for bird eggshells. The area has been detected in fossil bones despite the fossilization process.
Intramedullary is a medical term meaning the inside of a bone. Examples include intramedullary rods used to treat bone fractures in orthopedic surgery and intramedullary tumors occurring in some forms of cancer or benign tumors such as an enchondroma.
# Virgil Reading the Aeneid to Augustus and Octavia

Virgil Reading the Aeneid to Augustus and Octavia is a 1788 oil on canvas painting by Angelica Kauffman, now in the Hermitage Museum in St Petersburg, which it entered in 1902. A preparatory study is in the Royal Collection.
It was commissioned by Stanisław August Poniatowski, who kept it in the Lazienki Palace in Warsaw. It depicts a legend in Macrobius that Octavia the Younger fainted whilst Virgil was reading to her and Augustus a passage about her son Marcellus in Book VI of his Aeneid.
# Oscar Jackson (baseball)

Oscar "Oss" Jackson was an American baseball outfielder and first baseman in the late 19th century, who played for predecessor teams to the Negro leagues. He played for several teams from 1887 to 1906, spending the majority of his career with the Cuban Giants. He was the brother of fellow player Andrew Jackson.
# Mayor Vicente Villafañe

Mayor Vicente Villafañe is a settlement in northern Argentina. It is located in Formosa Province.
26°12′16″S 59°04′49″W﻿ / ﻿26.20444°S 59.08028°W﻿ / -26.20444; -59.08028
* This article about a place in Formosa Province, Argentina is a stub. You can help Wikipedia by expanding it.
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# Mücəkbinə

41°32′57″N 46°31′22″E﻿ / ﻿41.54917°N 46.52278°E﻿ / 41.54917; 46.52278
Mücəkbinə (also, Mudzhakhbina) is a village in the Zaqatala Rayon of Azerbaijan. The village forms part of the municipality of Dombabinə.
# Wilkins Strait

Wilkins Strait (78°10′N 112°00′W﻿ / ﻿78.167°N 112.000°W﻿ / 78.167; -112.000﻿ (Wilkins Strait)) is a natural waterway through the central Canadian Arctic Archipelago. It is mostly in the Northwest Territories, although its eastern extremity is in Nunavut. It separates Borden Island (to the north) from Brock Island (to the south-west) and Mackenzie King Island (to the south).
# Our Kind of Traitor

Our Kind of Traitor may refer to:
* Our Kind of Traitor (novel), a 2010 novel by John le Carré
* Our Kind of Traitor (film), a 2016 British spy thriller film, based on the novel
# Unna station

Unna station is the main passenger station in the Westphalian city of Unna in the German state of North Rhine-Westphalia. The other stations in the city that are served by regular passenger services are Unna-Königsborn, Unna West, Massen, Lünern and Hemmerde.

## History

The station was opened in 1855 as part of the Dortmund–Soest railway built by the Bergisch-Märkische Railway Company (BME) and equipped with an impressive station building, which was sold for non-rail purposes in 2005.
In 1866, the BME opened the line from Unna to Hamm to connect with the Cologne-Minden trunk line. Later the line was extended from Unna to Hagen, making Unna station into a railway junction of regional importance.
Between 1899 and 1901 the Prussian state railways opened the Fröndenberg–Kamen railway to connect the three east-west lines in the area. The southern part connected with the line to Menden, which was opened in 1872; this line was extended in 1912 to Neuenrade as the Hönne Valley Railway. The northern part was opened later for freight in 1900 and a year later for passenger traffic. This route is now worked only as far as Unna-Königsborn, as line S 4 of the Rhine-Ruhr S-Bahn.
Between 1909 and 1950, the Unna-Kamen-Werne light railway also connected Unna station and Kamen station.

## Connections

Unna station is served by the Rhein-Münsterland-Express (RE 7, at 60-minute intervals), the Maas-Wupper-Express (RE 13, at 60-minute intervals), the Hönnetalbahn (RB 54, at 60-minute intervals), the Hellweg-Bahn (RB 59, at 30-minute intervals) and Rhine-Ruhr S-Bahn line S 4 (at 30-minute intervals). The station also serves as the central bus junction for the city.
# GNRI Class T2

The Great Northern Railway (Ireland) T2 class was a class of 4-4-2T tank locomotives. The GNR(I) had introduced the T class numbered 185–189 in 1913. They were designed for both suburban services and longer runs such as Dublin to Drogheda and Belfast to Armagh. They proved so successful that a further twenty were commissioned in 1921, 1924 and 1929. Although externally identical in appearance to the T, they were classified as the T2 class having larger tanks and higher boiler pressure, and were used successfully on both fast passenger work and freight.
Roster :
| Manufacturer | Serial No. | Date | GNR(I) No. | 1958 owner | 1958 No. | Withdrawn | Notes |
| Beyer, Peacock & Co. | 6035 | 1921 | 1 | CIÉ | — | 1959 | Fitted for oil-firing 1946–47 |
| Beyer, Peacock & Co. | 6036 | 1921 | 2 | UTA | 2X | 1960 | Fitted for oil-firing 1946–47 |
| Beyer, Peacock & Co. | 6037 | 1921 | 3 | CIÉ | 3N | 1963 | |
| Beyer, Peacock & Co. | 6038 | 1921 | 4 | UTA | 4X | 1960 | |
| Beyer, Peacock & Co. | 6039 | 1921 | 5 | UTA | 5X | 1964 | |
| Nasmyth, Wilson & Co. | 1423 | 1924 | 21 | UTA | — | 1958 | |
| Nasmyth, Wilson & Co. | 1424 | 1924 | 30 | UTA | 30X | 1961 | |
| Nasmyth, Wilson & Co. | 1425 | 1924 | 115 | CIÉ | — | 1959 | Fitted for oil-firing 1946–47 |
| Nasmyth, Wilson & Co. | 1426 | 1924 | 116 | CIÉ | 116N | 1961 | Fitted for oil-firing 1946–47 |
| Nasmyth, Wilson & Co. | 1427 | 1924 | 139 | CIÉ | — | 1959 | |
| Nasmyth, Wilson & Co. | 1435 | 1924 | 142 | UTA | 142X | 1960 | |
| Nasmyth, Wilson & Co. | 1436 | 1924 | 143 | CIÉ | 143N | 1963 | |
| Nasmyth, Wilson & Co. | 1437 | 1924 | 144 | CIÉ | — | 1959 | |
| Nasmyth, Wilson & Co. | 1438 | 1924 | 147 | CIÉ | 67N | 1960 | Renumbered 67 in 1948 |
| Nasmyth, Wilson & Co. | 1439 | 1924 | 148 | UTA | — | 1958 | Renumbered 69 in 1948 |
| Beyer, Peacock & Co. | 6630 | 1929 | 62 | CIÉ | 62N | 1960 | |
| Beyer, Peacock & Co. | 6631 | 1929 | 63 | CIÉ | — | 1959 | |
| Beyer, Peacock & Co. | 6632 | 1929 | 64 | UTA | 64X | 1960 | |
| Beyer, Peacock & Co. | 6633 | 1930 | 65 | CIÉ | 65N | 1960 | |
| Beyer, Peacock & Co. | 6634 | 1930 | 66 | UTA | 66X | 1960 | |

## Model

The T2 is currently available as a 00 gauge etched-brass kit from Studio Scale Models. It includes transfers, brass etches, most nameplates and cast white metal parts.
# Venda (disambiguation)

Venda was a territory in South Africa.
Venda may also refer to:
* Venda people, an ethnic group of South Africa and Zimbabwe
* Venda language, the language they speak
* University of Venda, in South Africa
* Venda Inc, a technology company
* Monte Venda, a mountain in Italy
* La venda, a 2019 song
* Valeri F. Venda, Russian psychologist, engineer, and designer
# USS Prairie (AD-5)

USS Prairie (AD-5), formerly Morgan Liner SS El Sol, was built in 1890 by William Cramp & Sons, Philadelphia. She was purchased by the United States Navy on 6 April 1898 from the Southern Pacific Company, and commissioned two days later at New York, Commander Charles J. Train in command.

## History

Prairie was converted into an auxiliary cruiser and assigned at first to the Northern Patrol Squadron and later to the North Atlantic Fleet. During the Spanish–American War, she served in Cuban waters July and August 1898. On 25 August she stranded in dense fog 3 miles east of the Amagansett, New York Life saving Station. The United States Life Saving Service ferried 216 troops to shore. She was pulled off the next day by the tug Brittania. She returned to Fore River, Massachusetts, on 28 August. She decommissioned on 15 March 1899 at Philadelphia.
Prairie was placed in reserve commission on 23 March 1899 and cruised with the naval militia off the Atlantic coast until she was decommissioned at New York on 18 February 1901. She carried government exhibits to France at the turn of the 20th century for the Paris Exposition. She was recommissioned at Boston on 9 November 1901 as a training ship, and remained with this mission until she was decommissioned at Boston on 14 June 1905.
She was recommissioned 26 September 1906 at Boston as a transport and was attached to the Atlantic Fleet. She protected American interests in Cuba, March to April 1907. Later, she resumed her training duties with the naval militia from May to September 1907, July to August 1908 and July to August 1909.
She transported 750 Marines to Santo Domingo in 1912 during the civil war there. She took part on the U.S. occupation of Veracruz in 1914, firing her 3-inch guns at the Naval Academy and other tactical targets, on 21 April 1914.
Converted to a destroyer tender in late 1917, Prairie served during World War I.
Prairie was decommissioned for the final time on 22 November 1922 at San Diego, California, and was struck from the Navy List. She was sold on 22 June 1923 to Louis Rothenberg, Oakland, California.
# Mücver

Mücver is a Turkish fritter or pancake, made from grated zucchini (courgette). They are typically pan-fried in oil and their batter often includes a mixture of eggs, onion, dill, parsley, flour, and sometimes potatoes and cheese (beyaz peynir or kaşar). They are similar to Jewish latkes and potato pancakes from various cultures.

## History

Though mücver is currently known as a vegetable patty made with zucchini, in the Ottoman cuisine, it used to be known as a cooking technique. Written as mücmer in Ottoman records, it transformed into mücver in modern Turkish.
# Musée des monuments français

Musée des Monuments français may refer to two separate museums in Paris:
* The Musée des Monuments français (1795–1816) created by Alexandre Lenoir
* The Musée national des Monuments Français, first opened in 1882
# Gone Are the Days

Gone Are the Days may refer to:
* Gone Are the Days!, a 1963 film starring Ossie Davis
* "Gone Are the Days", a track from the 2008 album Liverpool 8, written by Ringo Starr
* "Gone Are the Days", a 2021 song by Kygo featuring James Gillespie
* Gone Are the Days (novel), a 2016 semi-autobiographical book by Gaurav Sharma
* Gone Are the Days (2018 film), a 2018 film starring Lance Henriksen
# USS Saco

Three ships in the United States Navy have been named USS Saco for the Saco River and for the Saco, Maine.
* The first USS Saco (1863) was a gunboat launched in 1863, served in the American Civil War and sold in 1883.
* The second USS Saco (YT-31) was a steam tugboat, built in 1912. She was acquired by the Navy in 1918 and served as a yard tug until 1927.
* The third USS Saco (YTB-796) was a yard tug launched into service in 1968 and struck from the Naval Vessel Register in 2005, after serving in Guam.
# Flix Premiere

Flix Premiere is a British media-services provider founded in 2015 by Martin Warner. The company's primary business is its subscription-based streaming OTT service, which offers online streaming of films, including some produced in-house. Two months after its UK opening, it premiered in the United States. The Guardian described the site as a supermarket for indie cinema, noting that it were few familiar titles available on the site, but that those available were the "best of the bunch" from film festivals and not available on other platforms.

## Devices

The service is part of a pool of streaming services including Netflix and Amazon. It is available through its website, Apple TV and mobile applications.
# Oscar Jacobsson

Oscar Jacobsson (Göteborg, 1889 – Solberga, December 25, 1945) was a Swedish comic creator and cartoonist who started his career in 1918 when his first newspaper illustration was published. Jacobsson's first illustrations were published in Naggen.
In 1920, he created the comic strip Adamson for the publication Söndags-Nisse. Adamson himself was a (usually) silent little cigar-smoking man with a big hat and frequent misadventures.
The strip soon became very popular and became published in hundreds of newspapers all over the world. In the United States, it became known as "Silent Sam".
Jacobsson also worked for other publications. His illustrations frequently appeared in magazines and papers like Exlex, Dagens Nyheter and Lutfisken. Near the end of his stellar career, Jacobsson created another comic character: Abu Fakir. This was published in Vi.

## Keeping Adamson Alive

'Adamson' outlived his creator; the Danish artist Viggo Ludvigsen continued the comic strip for nearly two decades after Oscar Jacobsson's death in 1945. And in the U.S. two artists kept Jacobson alive—Henry Thol from 1935 to 1940 and Jeff Hayes from 1941 to 1953.

## The Adamson Award

In 1965, the Swedish Comic Academy founded the "Adamson Awards" in Jacobsson's honor. This "Nobel Prize of comics" is given to one Swedish and one international comic creator every year.
# NGC 7674

NGC 7674 is a spiral galaxy located in the constellation Pegasus. It is located at a distance of about 350 million light years from Earth, which, given its apparent dimensions, means that NGC 7674 is about 125,000 light years across. It was discovered by John Herschel on August 16, 1830.

## Characteristics

The galaxy is seen nearly face-on, at an inclination of 31 degrees. The central bar-shaped structure, measuring 15×5 arcseconds is made up of stars. The galaxy has two spiral arms that become broader as the distance increases. One arm vanishes at the point it overlaps with the nearby galaxy NGC 7674A. The shape of NGC 7674, including the long narrow streamers emanating northeast and northwest of the galaxy can be accounted for by tidal interactions with its companions. There is no dwarf galaxy seen inside the streamers. It is featured in Arp's Atlas of Peculiar Galaxies as number 182, in the category "galaxies with narrow filaments".
NGC 7674 has a powerful active nucleus of the kind known as a type 2 Seyfert that is perhaps fed by gas drawn into the center through the interactions with the companions. In 1975, observations of excess ultraviolet emission led to designation as Markarian 533 in Markarian's catalog. Later, using spectropolarimetry, emission characteristic of a hidden broad-line region (BLR), visible only in the polarized flux spectrum was detected, implying that the nucleus of NGC 7674 is an obscured type 1 Seyfert, hidden by a dust torus. In the center of NGC 7674 lies a supermassive black hole whose mass is estimated to be nearly 3.63×10$^7$ M$_☉$ based on stellar velocity dispersion. When observed in radio waves, NGC 7674 features two radio jets with an S-shape, 0.7 kpc long. The reason for this shape may be a change in the black hole spin axis due to a minor merger, the presence of a binary black hole or due to interactions with the interstellar medium. Two radio sources with characteristics similar to accreting supermassive black holes have been observed in the centre of NGC 7674, at a projected separation of 0.35 parsec.
NGC 7674 falls into the family of luminous infrared galaxies, with its infrared luminosity being 10$^{11.54}$ L$_☉$. The luminous infrared galaxies are characterised by intense star forming activity. The total star formation rate in NGC 7674 is estimated to be 54 M$_☉$ per year, and the star formation rate at the nucleus is 4.3 M$_☉$ per year.
Two supernovae have been observed in NGC 7674, SN 2011ee (type Ic, mag 18.6) and SN 2011hb (type Ia, mag 18.8).

## Nearby galaxies

NGC 7674 is the brightest and largest member of the isolated Hickson 96 compact group of galaxies, consisting of four galaxies. NGC 7674 forms a pair with its smaller companion NGC 7674A, which lies 34 arcseconds to the north. NGC 7675, an elliptical galaxy, lies 2.2 arcminutes to the east.
# Negromantis milloti

Negromantis milloti is a species of praying mantis found in Madagascar.
# Frasne (disambiguation)

Frasne is a commune in the Doubs department in the Franche-Comté region in eastern France. Frasne may also refer to:
* Frasne-les-Meulières, a commune in the Jura department in Franche-Comté in eastern France
* Frasne-le-Château, a commune in the Haute-Saône department in the region of Franche-Comté in eastern France
See also
* Gare de Frasne, a railway station located in Frasne on the Dijon–Vallorbe railway and Frasne–Les Verrières railway
* Frasnes (disambiguation)
# Todee District

Todee District is one of four districts located in Montserrado County, Liberia. There was a former Armed Forces of Liberia base there housing the Tubman Military Academy and Second Infantry Battalion in 1984 and there have been discussions post-2003 of rebuilding the base.
6°35′46″N 10°29′06″W﻿ / ﻿6.596°N 10.485°W﻿ / 6.596; -10.485
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# Märchen der Welt – Puppenspiel der kleinen Bühne

Märchen der Welt – Puppenspiel der kleinen Bühne is a West German television series.
# Musée du 11 Conti

The Musée du 11 Conti (previously: Musée de la Monnaie de Paris) is a museum dedicated to the manufacturing techniques and the know-how of the Monnaie de Paris. It is located in the 6th arrondissement in Paris. The museum houses exhibition rooms and workshops. The museum is interactive, showcasing touchable items, tactile graphics and olfactory devices.
Labeled Museum of France, Monnaie de Paris has the mission of managing and managing reserves, inventory, verification, restoration, scientific studies, collaborations with other institutions.

## History

The museum was created in 1833 by Jean-Baptiste Henry Collin de Sussy, and inaugurated by Louis-Philippe I on November 8, 1833. It was initially curated by Fernand Mazerolle (1868–1941).
A refreshed museography was presented in 1991, designed by Katherine Gruel (Ancient), Jean Belaubre (Medieval), and Bruno Collin (Modern and Contemporary). All three autographed the catalog of the museum's collections.
It closed its doors on July 31, 2010, for renovation over two years.The Musée de la Monnaie de Paris finally reopened on September 30, 2017.

## Displays

Nearly 1,800 objects are presented over 1,200 m$^2$. The new museum exhibits in an interactive and playful scenography highlighting the last factory in Paris. Also on display are key pieces from the collection of the Monnaie de Paris, such as ancient Greek coinage, the gold crown of Philip VI (Capetian coin), a 10 louis d'or coin, a standard meter in platinum, a golden ōban, a collection of Akan weights, treasures of Hué, etc.
# Wiedmann

Wiedmann is a German surname. Notable people with the surname include:
* Frederik Wiedmann (born 1981), German composer
* Siegfried K. Wiedmann (born 1938), German electrical engineer
* Willy Wiedmann (1929–2013), German artist, writer and art dealer
# USS Sacagawea

USS Sacagawea may refer to the following ships of the United States Navy:
* USS Sacagawea (YT-241), was a tugboat, launched in 1942; acceptance by the Navy was canceled in 1942, but she was retained by the Maritime Commission.
* USS Sacagawea (YT-326), was a tugboat, acquired by the Navy and renamed in 1942, and struck in 1945.
* USNS Sacagawea (T-AKE-2) is a Lewis and Clark-class dry cargo ship, launched in 2006 and in active service
# Flixton

Flixton may refer to the following places in England:
* Flixton, Greater Manchester, part of the Metropolitan Borough of Trafford
** Flixton F.C.
** Flixton railway station
** Flixton (ward)
** Flixton Girls' School
** Flixton Junior School
* Flixton, North Yorkshire, a village near Scarborough
* Flixton, Lothingland, a village near Lowestoft, in Suffolk
* Flixton, The Saints, a village south of Bungay, in Suffolk
** RAF Flixton
# Percan

Percan is a surname. Notable people with the surname include:
* Diego Percan (born 2001), Spanish footballer
* Lidija Percan (born 1938), Istrian Croatian singer
* Renato Percan (1936–2013), Istrian Croatian painter
# Miguel Henrique Otero

Miguel Henrique Otero (born 1947) is a Venezuelan journalist, and he is the President and CEO of El Nacional newspaper. He was Vice President of Bloque de Prensa, the main press association in his home country. Otero is recognized as a pioneer in the use of new technologies, in journalism and media companies management. He is also the former President of Grupo de Diarios America, board member of the Inter American Press Association and of the World Association of Newspapers and News Publishers, WAN-IFRA.

## Education

Otero holds a bachelor's degree in mathematics from the Central University of Venezuela. After his postgraduate studies in Business Administration, he traveled to Europe where he studied economics at Churchill College, Cambridge University and Sociology at Sorbonne University. After returning to Venezuela he began an extensive cultural, politics and business activity which continues today.

## Public activity

In 1977 he was appointed as General Secretary of the Caracas Athenaeum the country's leading non-governmental cultural institution centered on the arts. He launched the Caracas Athenaeum Editorial where 600 titles were published. In 1983 he was elected independent deputy at the National Congress representing Anzoátegui's State appointed by Democracia Cristiana. In 1988 he is reelected and in 1993 he repeats once again he repeats but on uninominal basis. In late 2007 Otero founded an opposition movement called Movimiento 2D, which supported the electoral coalition of Venezuelan political parties, Mesa de la Unidad Democrática (MUD) in the 2010 Venezuelan parliamentary election. In April 2015, judge María Eugenia Núñez ordered a prohibition to leave Venezuela to 22 directors of El Nacional, La Patilla and Tal Cual, including Miguel Henrique Otero, they were accused of aggravated defamation to the President of the National Assembly, Diosdado Cabello. As a result of the threats and the legal measures, he left Venezuela and have been forced to run his newspaper from Madrid. The Venezuelan government targeted him for several lawsuits of political nature and has publicly threatened him with imprisonment if he returns to his country. Otero has expressed his support for Juan Guiado, President of the National Assembly of Venezuela, who in January 2019 was declared acting President of Venezuela.

## Awards

On November 23, 2010, he received the award Premio Internacional de Periodismo prize presented by el diario El Mundo, Spain. On 2015, he received the Premio Luca De Tena which is granted by diario ABC from Spain. Miguel Henrique Otero's nomination was proposed by the former Spanish president José María Aznar and the former Colombian president Andrés Pastrana. Otero on July 13, 2017, got the Libertad award given by the Club Liberal from Spain. On February 12, 2020, The World Law Foundation awarded him with a medal for his defense of democracy.