# List of UK R&B Singles Chart number ones of 2006

The UK R&B Chart is a weekly chart that ranks the 40 biggest-selling singles and albums that are classified in the R&B genre in the United Kingdom. The chart is compiled by the Official Charts Company, and is based on both physical and digital sales. This is a list of the UK's biggest R&B hits of 2006.

## Number ones

Key :
| † | Best-selling R&B single of the year |
| Issue date | Single | Artist |
| 1 January | "When I'm Gone | Eminem |
| 8 January | "When I'm Gone | Eminem |
| 15 January | "When I'm Gone | Eminem |
| 22 January | "Nasty Girl" | The Notorious B.I.G. featuring Diddy, Jagged Edge, Nelly, and Avery Storm |
| 29 January | "Nasty Girl" | The Notorious B.I.G. featuring Diddy, Jagged Edge, Nelly, and Avery Storm |
| 5 February | "Run It!" | Chris Brown featuring Juelz Santana |
| 12 February | "Nasty Girl" | The Notorious B.I.G. featuring Diddy, Jagged Edge, Nelly and Avery Storm |
| 19 February | "Nasty Girl" | The Notorious B.I.G. featuring Diddy, Jagged Edge, Nelly and Avery Storm |
| 26 February | "Put Your Records On" | Corinne Bailey Rae |
| 5 March | "Beep" | The Pussycat Dolls featuring Will.I.Am |
| 12 March | "Beep" | The Pussycat Dolls featuring Will.I.Am |
| 19 March | "Pump It" | The Black Eyed Peas |
| 26 March | "So Sick" | Ne-Yo |
| 2 April | "So Sick" | Ne-Yo |
| 9 April | "Crazy" † | Gnarls Barkley |
| 16 April | "Crazy" † | Gnarls Barkley |
| 23 April | "Crazy" † | Gnarls Barkley |
| 30 April | "Crazy" † | Gnarls Barkley |
| 7 May | "Crazy" † | Gnarls Barkley |
| 14 May | "Crazy" † | Gnarls Barkley |
| 21 May | "Crazy" † | Gnarls Barkley |
| 28 May | "Crazy" † | Gnarls Barkley |
| 4 June | "Crazy" † | Gnarls Barkley |
| 11 June | "Crazy" † | Gnarls Barkley |
| 18 June | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| 25 June | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| 2 July | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| 9 July | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| 16 July | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| 23 July | "Unfaithful" | Rihanna |
| 30 July | "Ain't No Other Man" | Christina Aguilera |
| 6 August | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| 13 August | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| 20 August | "Ridin'" | Chamillionaire featuring Krayzie Bone |
| 27 August | "Déjà Vu" | Beyoncé featuring Jay-Z |
| 3 September | "SexyBack" | Justin Timberlake |
| 10 September | "SexyBack" | Justin Timberlake |
| 17 September | "SexyBack" | Justin Timberlake |
| 24 September | "SexyBack" | Justin Timberlake |
| 1 October | "I Don't Need a Man" | The Pussycat Dolls |
| 8 October | "Come to Me" | P. Diddy featuring Nicole Scherzinger |
| 15 October | "Come to Me" | P. Diddy featuring Nicole Scherzinger |
| 22 October | "If You Got the Money" | Jamie T |
| 29 October | "Irreplaceable" | Beyoncé |
| 5 November | "Irreplaceable" | Beyoncé |
| 12 November | "Irreplaceable" | Beyoncé |
| 19 November | "Smack That" | Akon featuring Eminem |
| 26 November | "Smack That" | Akon featuring Eminem |
| 3 December | "Smack That" | Akon featuring Eminem |
| 10 December | "Smack That" | Akon featuring Eminem |
| 17 December | "Tell Me" | P. Diddy featuring Christina Aguilera |
| 24 December | "Smack That" | Akon featuring Eminem |
| 31 December | "Tell Me" | P. Diddy featuring Christina Aguilera |