# Lachnospiraceae

The Lachnospiraceae are a family of obligately anaerobic, variably spore-forming bacteria in the order Eubacteriales that ferment diverse plant polysaccharides to short-chain fatty acids (butyrate, acetate) and alcohols (ethanol). These bacteria are among the most abundant taxa in the rumen and the human gut microbiota. Members of this family may protect against colon cancer in humans by producing butyric acid. Lachnospiraceae have been found to contribute to diabetes in genetically susceptible (ob/ob) germ-free mice.

## Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI)
| 16S rRNA based LTP_10_2024 | 120 marker proteins based GTDB 09-RS220 |
| Lachnospiraceae | Lachnospiraceae Catonella Moore & Moore 1994 "Ca. Caccomorpha" Gilroy et al. 2021 "Lachnoclostridium" Yutin & Galperin 2013 Eubacterium xylanophilum van Gylswyk & van der Toorn 1985 Jutongia Liu et al. 2022 Butyribacter Zou et al. 2021 Clostridium_AI Velocimicrobium Wylensek et al. 2021 Anaerosporobacter Jeong et al. 2007 Mobilisporobacter Mbengue et al. 2016 Anaeromicropila Ueki et al. 2023 Mobilitalea Podosokorskaya et al. 2014 Anaerocolumna Ueki et al. 2016 Coprococcus catus Holdeman & Moore 1974 Frisingicoccus Lagkouvardos et al. 2016 "Ca. Onthocola" Gilroy et al. 2021 "Ca. Scybalocola faecipullorum" Gilroy et al. 2021 Catenibacillus Braune & Blaut 2018 Eubacterium ruminantium Bryant 1959 "Wujia" Liu et al. 2021 Coprococcus Holdeman & Moore 1974 "Ca. Scybalomonas" Gilroy et al. 2021 Anaerobutyricum Shetty et al. 2018 "Ca. Fimousia" Gilroy et al. 2021 Anaerostipes Schwiertz et al. 2002 Bovifimicola Hitch et al. 2025 Parasporobacterium Lomans et al. 2004 Eubacterium_S & G Eshraghiella Fatahi-Bafghi 2024 Falcatimonas Watanabe et al. 2016 Clostridium fimetarium Kotsyurbenko et al. 1997 Bacteroides pectinophilus Jensen & Canale-Parola 1987 Lachnospira Bryant & Small 1956 Anthropogastromicrobium Hitch et al. 2022 Cuneatibacter Lagkouvardos et al. 2016 "Ca. Fimimorpha" Gilroy et al. 2021 "Ca. Pseudolachnospira" Glendinning et al. 2020 Hominifimenecus Afrizal et al. 2023 "Ca. Paralachnospira sangeri" Glendinning et al. 2020 Lientehia Abdugheni et al. 2023 "Ca. Avilachnospira" Gilroy et al. 2021 Oribacterium Carlier et al. 2004 Moryella Carlier, K'ouas & Han 2007 Johnsonella Moore & Moore 1994 Lachnoanaerobaculum Hedberg et al. 2012 Alitiscatomonas Hitch et al. 2022 "Ca. Copromonas" Gilroy et al. 2021 non Dobell 1908 "Ca. Ventrisoma" Gilroy et al. 2021 Clostridium_R Otoolea Afrizal et al. 2023 Lachnoclostridium_A "Ca. Caccovicinus" Gilroy et al. 2021 Enterocloster Haas & Blanchard 2020 Brotaphodocola Afrizal et al. 2023 "Ca. Hungatella pullicola" Gilroy et al. 2021 Hungatella Kaur et al. 2014 Lacrimispora Haas & Blanchard 2020 Acetitomaculum Greening & Leedle 1995 Diplocloster Chaplin et al. 2022 Anaerosacchariphilus Kim et al. 2019 "Ca. Merdenecus" Gilroy et al. 2021 Anaerobium Patil et al. 2015 Lachnotalea Jarzembowska et al. 2016 Hominiventricola Afrizal et al. 2023 Laedolimicola Hitch et al. 2022 "Ca. Merdiplasma" Gilroy et al. 2021 "Ca. Choladousia Gilroy et al. 2021 Marvinbryantia Wolin et al. 2008 Muricoprocola Hitch et al. 2022 Murimonas Klaring et al. 2015 Robinsoniella Cotta et al. 2009 "Ca. Hominisplanchenecus murintestinalis" Afrizal et al. 2022 Hominisplanchenecus Afrizal et al. 2023 "Ca. Limivivens Gilroy et al. 2021 Shuttleworthella Deshmukh & Oren 2024 [Shuttleworthia] "Ca. Weimeria" Scarborough et al. 2020 "Ca. Pullilachnospira gallistercoris" Gilroy et al. 2021 Pararoseburia Abdugheni et al. 2022 Pseudobutyrivibrio van Gylswyk, Hippe & Rainey 1996 Eubacterium oxidoreducens corrig. Krumholz & Bryant 1986 Eubacterium ramulus Moore, Johnson &Holdeman 1976 Brotonthovivens Hitch et al. 2022 "Petralouisia" Afrizal et al. 2022 Eubacterium plexicaudatum Wilkins, Fulghum & Wilkins 1974 Roseburia_C Roseburia zhanii Liu et al. 2022 Roseburia Stanton & Savage 1983 Lachnobacterium Whitford et al. 2001 "Roseburia porci" Wylensek et al. 2020 Agathobacter Rosero et al. 2016 Butyrivibrio Bryant & Small 1956 Suilimivivens Hitch et al. 2021 Acetatifactor Pfeiffer et al. 2013 Kineothrix Haas & Blanchard 2017 Gallintestinimicrobium Hitch et al. 2022 Eisenbergiella Amir et al. 2014 Suipraeoptans corrig. Wylensek et al. 2021 "Aequitasia" Vera-Ponce de Leon et al. 2022 Claveliimonas Hisatomi et al. 2023 Extibacter Lagkouvardos et al. 2017 Dorea Taras et al. 2002 Dorea hominis Liu et al. 2022 "Massilistercora" Tall et al. 2020 "Dorea phocaeensis" Takakura et al. 2019 Merdimonas Seo et al. 2017 Clostridium scindens Morris et al. 1985 Sporofaciens Rasmussen et al. 2021 Dorea_A "Bariatricus" Bessis et al. 2016 Faecalimonas Sakamoto, Iino & Ohkuma 2017 Sellimonas Seo et al. 2016 Hespellia Whitehead et al. 2004 Mediterraneibacter butyricigenes Kim et al. 2019 Ruminococcus_B "Luxibacter" Naud et al. 2021 Muricomes Lagkouvardos et al. 2016 [incl. Faecalicatena] Schaedlerella Soh et al. 2019 Mediterraneibacter Togo et al. 2019 Porcincola Wylensek et al. 2021 Chordicoccus Gaffney et al. 2023 "Ca. Alectryocaccobium" Gilroy et al. 2021 Bilifractor Wylensek et al. 2021 "Ca. Scatomonas" Gilroy et al. 2021 Novisyntrophococcus Chai et al. 2021 Fusicatenibacter Takada et al. 2013 "Ca. Egerieimonas faecigallinarum" Gilroy et al. 2021 "Ca. Egerieimonas" Gilroy et al. 2021 "Ca. Pullilachnospira" Gilroy et al. 2021 Oliverpabstia Wylensek et al. 2021 Ruminococcus_G Lactonifactor Clavel et al. 2007 Blautia Liu et al. 2008 Blautia_A |
Unassinged Genera:
* "Africanella" Alou, Fournier & Raoult 2016 non Vermeij & Houart, 1999
* Anaerolentibacter Yan et al. 2024
* Anaerotaenia Ueki et al. 2016
* Chakrabartyella Pardesi et al. 2023
* "Ca. Colinaster" Gilroy et al. 2022
* "Ca. Darwinimomas" Gilroy et al. 2022
* "Ca. Epulonipiscioides" Ngugi et al. 2017 corrig. Oren et al. 2020
* "Ca. Equihabitans" Gilroy et al. 2022
* Fusibacillus Bai et al. 2024 non Pribram 1929
* "Fusimonas" Kusada et al. 2017
* "Gluceribacter" corrig. Kawata et al. 2021
* "Ca. Hippenecus" Gilroy et al. 2022
* Hoministercoradaptatus Hitch et al. 2022
* Howardella Cook et al. 2007
* "Ca. Lachnocurva" Holm et al. 2020
* "Maccoya" Hitch et al. 2024
* "Ca. Merdinaster" Gilroy et al. 2022
* "Ca. Minthocola" Gilroy et al. 2022
* "Naizhengia" Huang et al. 2024
* "Sakamotonia" Hitch et al. 2024
* "Sanxizhangella" Huang et al. 2024
* Suonthocola Hitch et al. 2022
* Sporobacterium Mechichi et al. 1999
* Syntrophococcus Krumholz & Bryant 1986
* "Weimerbacter" Scarborough et al. 2019
* "Yonghella" Huang et al. 2024