# List of Billboard Mainstream Top 40 number-one songs of 2016

This is a list of songs which reached number one on the Billboard Mainstream Top 40 (or Pop Songs) chart in 2016.
During 2016, a total of 21 singles hit number-one on the charts, making 2016 the year with the most number-one hits on the Mainstream Top 40.

## Chart history

Key :
| † | Indicates best-performing single of 2016 |
| Issue date | Song | Artist(s) |
| January 2 | "Sorry" | Justin Bieber |
| January 9 | "Sorry" | Justin Bieber |
| January 16 | "Sorry" | Justin Bieber |
| January 23 | "Same Old Love" | Selena Gomez |
| January 30 | "Same Old Love" | Selena Gomez |
| February 6 | "Here" | Alessia Cara |
| February 13 | "Love Yourself"† | Justin Bieber |
| February 20 | "Love Yourself"† | Justin Bieber |
| February 27 | "Love Yourself"† | Justin Bieber |
| March 5 | "Love Yourself"† | Justin Bieber |
| March 12 | "Love Yourself"† | Justin Bieber |
| March 19 | "Stressed Out" | Twenty One Pilots |
| March 26 | "My House" | Flo Rida |
| April 2 | "My House" | Flo Rida |
| April 9 | "My House" | Flo Rida |
| April 16 | "Hands to Myself" | Selena Gomez |
| April 23 | "Me, Myself & I" | G-Eazy and Bebe Rexha |
| April 30 | "Me, Myself & I" | G-Eazy and Bebe Rexha |
| May 7 | "Pillowtalk" | Zayn |
| May 14 | "Pillowtalk" | Zayn |
| May 21 | "I Took a Pill in Ibiza" (SeeB Remix) | Mike Posner |
| May 28 | "7 Years" | Lukas Graham |
| June 4 | "Work from Home" | Fifth Harmony featuring Ty Dolla $ign |
| June 11 | "Work from Home" | Fifth Harmony featuring Ty Dolla $ign |
| June 18 | "Can't Stop the Feeling!" | Justin Timberlake |
| June 25 | "Can't Stop the Feeling!" | Justin Timberlake |
| July 2 | "Can't Stop the Feeling!" | Justin Timberlake |
| July 9 | "Don't Let Me Down" | The Chainsmokers featuring Daya |
| July 16 | "Don't Let Me Down" | The Chainsmokers featuring Daya |
| July 23 | "Don't Let Me Down" | The Chainsmokers featuring Daya |
| July 30 | "One Dance" | Drake featuring Wizkid and Kyla |
| August 6 | "Cheap Thrills" | Sia featuring Sean Paul |
| August 13 | "Cheap Thrills" | Sia featuring Sean Paul |
| August 20 | "Cheap Thrills" | Sia featuring Sean Paul |
| August 27 | "Cheap Thrills" | Sia featuring Sean Paul |
| September 3 | "Cheap Thrills" | Sia featuring Sean Paul |
| September 10 | "Ride" | Twenty One Pilots |
| September 17 | "Ride" | Twenty One Pilots |
| September 24 | "Send My Love (To Your New Lover)" | Adele |
| October 1 | "Cold Water" | Major Lazer featuring Justin Bieber and MØ |
| October 8 | "Closer" | The Chainsmokers featuring Halsey |
| October 15 | "Closer" | The Chainsmokers featuring Halsey |
| October 22 | "Closer" | The Chainsmokers featuring Halsey |
| October 29 | "Closer" | The Chainsmokers featuring Halsey |
| November 5 | "Closer" | The Chainsmokers featuring Halsey |
| November 12 | "Closer" | The Chainsmokers featuring Halsey |
| November 19 | "Closer" | The Chainsmokers featuring Halsey |
| November 26 | "Closer" | The Chainsmokers featuring Halsey |
| December 3 | "Closer" | The Chainsmokers featuring Halsey |
| December 10 | "Closer" | The Chainsmokers featuring Halsey |
| December 17 | "Closer" | The Chainsmokers featuring Halsey |
| December 24 | "Side to Side" | Ariana Grande featuring Nicki Minaj |
| December 31 | "Side to Side" | Ariana Grande featuring Nicki Minaj |