OpenLLM-France/wikimedia huggingface dataset:
# Mycophenolic acid acyl-glucuronide esterase

The enzyme mycophenolic acid acyl-glucuronide esterase (EC 3.1.1.93, mycophenolic acid acyl-glucuronide deglucuronidase; AcMPAG deglucuronidase; systematic name mycophenolic acid O-acyl-glucuronide-ester hydrolase), is in humans encoded by the ABHD10 gene, and catalyses the reaction
    mycophenolic acid O-acyl-glucuronide + H$_2$O $\rightleftharpoons$ mycophenolate + D-glucuronate
This liver enzyme deglucuronidates mycophenolic acid O-acyl-glucuronide. Mycophenolic acid acyl-glucuronide (AcMPAG) is an important product in the metabolism of mycophenolic acid, and ABHD10 is the major esterase responsible for the AcMPAG and probenecid acyl glucuronide deglucuronidation in human liver.

## Structure
### Gene

ABHD10 gene is located at chromosome 3q13.2, consisting of 6 exons.

### Protein

Human ABHD10 is a 297 amino acid protein with a molecular mass of 33 kDa, the mature form of which is a 28-kDa protein and has the nucleophile-His-acid catalytic triad. ABHD10 is a mitochondrial protein with a predicted leader sequence and the proteolytic cleavage site is at residues 46–47.

## Function

ABHD10 was identified in 2012, and only two main functions have been reported. First, ABHD10 is involved in the deglucuronidation of AcMPAG in human liver. The activity of this enzyme could attenuate the AcMAPG formation. AcMAPG might be responsible for some adverse effects of mycophenolate mofetil therapy because it promotes the release of TNF-α and IL-6, and it also binds to enzymes that are essential for the control of the energy and redox state of the cells. Thus, the function of ABHD10 could also be regarded as detoxification. Second, ABHD10 counteracts PRAG via deglucuronidation in human liver. As a widely used uricosuric agent, probenecid is mainly metabolized to probenecid acyl glucuronide (PRAG), which is a causal substance of severe allergic or anaphylactoid reaction. The PRAG deglucuronidation catalyzed by ABHD10 could suppress PRAG formation and related adverse reaction.

## Clinical significance

Mycophenolate mofetil is the prodrug of mycophenolic acid (MPA) and widely used for the prevention of acute rejection after solid organ transplantation. MPA could be metabolized to AcMPAG, which is responsible for adverse effects of MMF therapy such as leucopenia or gastrointestinal toxicity. Deglucuronidation of AcMPAG may be a detoxification process and human ABHD10 could be a potential therapeutic drug. ABHD10 may also be used to regulate adverse effects of probenecid, because it catalyze the deglucuronidation of PRAG.

## Interactions

ABHD10 has also been known to interact with:
* PMSF
* ML257
* Probenecid acyl glucuronide (PRAG)
# Massacre of the Innocents (Matteo di Giovanni)

Massacre of the Innocents is a tempera on panel painting by Matteo di Giovanni, produced between 1450 and 1500 possibly in 1468, 1478, or 1488) probably in Siena. It was commissioned by Alfonso II of Naples, then living in Siena as part of the campaign against the Medici. It was probably produced to commemorate the inhabitants of Otranto killed by the Ottomans in 1480 whose relics were moved into the church of Santa Caterina at Formiello at Alfonso's request - the same church also originally housed the painting. It is now in the National Museum of Capodimonte.
# Mărăcineanu

Mărăcineanu is a Romanian-language surname that may refer to:
* Roxana Mărăcineanu, French politician, swimmer, and TV consultant
* Ștefania Mărăcineanu, Romanian physicist
* Valter Mărăcineanu, Romanian soldier
# Pinus pinceana

Pinus pinceana, with the common names weeping pinyon and Pince's pinyon pine, is a species of conifer in the family Pinaceae.

## Distribution

This pine species is endemic to Mexico, in the states of: Durango; northern Coahuila, Nuevo León, and Zacatecas; central San Luis Potosí; and southern Querétaro and Hidalgo.
Its distribution extends over a distance of more than 750 kilometres (470 mi) from north to south.
The majority of its range it is found at altitudes between 1,100–2,600 metres (3,600–8,500 ft) in elevation, within arid areas.

## Description

Pinus pinceana forms a small tree or large shrub. Seeds are edible but produced infrequently.
It is an IUCN Red List Near threatened species, endangered by habitat loss.
# Masbate Provincial Board

The Masbate Provincial Board is the Sangguniang Panlalawigan (provincial legislature) of the Philippine province of Masbate.
The members are elected via plurality-at-large voting: the province is divided into three districts, the first district sending two members, and the second and third districts sending four members each to the provincial board; the number of candidates the electorate votes for and the number of winning candidates depends on the number of members their district sends. The vice governor is the ex officio presiding officer, and only votes to break ties. The vice governor is elected via the plurality voting system province-wide.
The districts used in appropriation of members is coextensive with the legislative districts of Masbate.
Aside from the regular members, the board also includes the provincial federation presidents of the Liga ng mga Barangay (ABC, from its old name "Association of Barangay Captains"), the Sangguniang Kabataan (SK, youth councils) and the Philippine Councilors League (PCL).

## Apportionment

| Elections | Seats per district | Seats per district | Seats per district | Ex officio seats | Total seats |
| Elections | 1st | 2nd | 3rd | Ex officio seats | Total seats |
| 2010–present | 2 | 4 | 4 | 3 | 13 |

## List of members
### Current members

These are the members after the 2019 local elections and 2018 barangay and SK elections:
* Vice Governor: Olga Kho (PDP–Laban)
| District | Board member | Board member | Party | Start of term | End of term |
| 1st | | Diosdado Alim | PDP–Laban | June 30, 2019 | June 30, 2022 |
| 1st | | Emilio Barsaga | NUP | June 30, 2019 | June 30, 2022 |
| 2nd | | Teddy Danao Jr. | Liberal | June 30, 2019 | June 30, 2022 |
| 2nd | | Jamon Espares | PDP–Laban | June 30, 2019 | June 30, 2022 |
| 2nd | | Kristoffer Espinosa | PDP–Laban | June 30, 2019 | June 30, 2022 |
| 2nd | | Allan Cos | PDP–Laban | June 30, 2019 | June 30, 2022 |
| 3rd | | Jason Arevalo | Independent | June 30, 2019 | June 30, 2022 |
| 3rd | | Rudy Alvarez | PDP–Laban | June 30, 2019 | June 30, 2022 |
| 3rd | | George Gonzales Jr. | PDP–Laban | June 30, 2019 | June 30, 2022 |
| 3rd | | Angela Lanete | NPC | June 30, 2019 | June 30, 2022 |
| League | Board member | Board member | Party | Start of term | End of term |
| ABC | | | Nonpartisan | July 30, 2018 | January 1, 2023 |
| PCL | | | | July 1, 2019 | June 30, 2022 |
| SK | | | Nonpartisan | June 8, 2018 | January 1, 2023 |
# Place-d'Armes

Place d'Armes may refer to
* Place d'Armes (Luxembourg), a square in Luxembourg City, Luxembourg
* Place-d'Armes, Paris, France
* Place d'Armes, in Montreal, Canada, an urban square
** Place-d'Armes (Montreal Metro), a transit station
** Le 500 Place D'Armes, a building in Montreal
* Place d'Armes (Quebec City), the central square of the old city
* Place d'Armes, the French name of Jackson Square in New Orleans, Louisiana, U.S.A.
* Place d'Armes, the French name of Plaza de Armas in Old San Juan, Puerto Rico
* Place d'Armes, a novel by Scott Symons
* Place-of-arms, an assembly area for troops within a fortification
# Məlikballı

Məlikballı (also Malikballi and Melikbally) is a village and municipality in the Ujar Rayon of Azerbaijan. It has a population of 1,372.
# Məliklər

Məliklər (also, Meliklyar) is a village and municipality in the Davachi Rayon of Azerbaijan. It has a population of 326.
# Massawepie Lake

Massawepie Lake is located in the town of Piercefield, in southern St. Lawrence County, New York, approximately 12 miles (19 km) southwest of the village of Tupper Lake, New York. The lake is also surrounded by the Massawepie Scout Camps. The name of the lake is of Iroquois origin, meaning "the beaver's lake". The outlet flows west into the South Branch Grass River.

## Fishing

The lake offers shore fishing, and there is a carry-down launch on the east shore on Massawepie Road with permission from the Massawepie Scout Camp. Public use is prohibited from June to August. Fish species present in the lake are lake trout, smallmouth bass, whitefish, walleye, yellow perch, black bullhead, rock bass, and white sucker.

## Geography

One of the most notable geographic features is the Massawepie Mire located immediately to the south of the lake. It is bordered by two long north-south eskers. Hundreds of acres in size, the bog is one of the largest of its kind in the Eastern United States and is almost entirely on the Boy Scout camp's property.

## History

In 1890, the Childwold Park House, commonly known as the Childwold Hotel, open on the shore of Massawepie Lake, just east of the main flagpole of the current camp. In the days before air-conditioning, upperclass residents of New York City would retreat to the Adirondacks to escape the summer heat. Visitors to Childwold Park would take the New York Central Railroad north from Utica and get off at Childwold Station. From there they would take a 7-mile (11 km) trip along the Carriage Road to the hotel. The hotel burned down in 1910.
# Pipunculus campestris

Pipunculus campestris is a species of fly in the family Pipunculidae. It is found in the Palearctic.

## Distribution

Europe.
# John G. Wallenmeier Jr.

John G. Wallenmeier Jr. (October 10, 1862 – October 25, 1917) was an American politician.

## Life

John G. Wallenmeier was born in Buffalo, New York on October 10, 1862, and grew up in the town of Tonawanda. In 1896, he supported William McKinley for President at the Republican New York state convention against the majority led by Thomas C. Platt who supported Levi P. Morton. After McKinley's election, he was appointed Postmaster of Tonawanda.
He married Hattie May Koch on November 14, 1883.
He was an alternate delegate to the 1904 Republican National Convention. He was New York State Treasurer from 1905 to 1906, elected in 1904, but was defeated for re-election in 1906 by Democrat Julius Hauser.
He died at his home in Tonawanda on October 25, 1917.
# John G. Walker

John G. Walker may refer to:
* John George Walker (1821 - 1893), Confederate general in the American Civil War
* John Grimes Walker (1835 - 1907), United States Navy admiral
# PiperWai

PiperWai is an American deodorant brand. It was featured on Shark Tank in December 2015 and received an offer from Barbara Corcoran. The product experienced the "Shark Tank effect" and sold out within five minutes of airing, with more than $1 million in sales over the next month. The company's founders, Sarah Ribner and Jess Edelstein, did not accept Corcoran's offer after a year of negotiations and became self-funded.

## Background

The name "PiperWai" comes from a combination of Edelstein's family dog's name, Piper, and a Guyana tribe called the Wai Wai. The brand is best known for developing all-natural deodorant made from charcoal, which was created in a Philadelphia, Pennsylvania kitchen. Edelstein gave the product to Ribner to test during a trip to South America in November 2013.
Afterward, Edelstein and Ribner received a $2,000 loan from their parents to produce the raw materials and develop a website. PiperWai was co-founded by Ribner and Edelstein in March 2014. In spring 2015, they raised $27,000 through a crowdfunding campaign for a branding redesign. PiperWai has retail distribution in more than 200 independent lifestyle boutiques and has 200,000 customers. PiperWai has received press from many media outlets and regularly frequents as a top choice of HSN with on air personality Noel Elie as their spokesmodel and wellness expert.

## Ingredients

The formula uses activated charcoal powder, which rubs clear and doesn't discolor clothing. According to Edelstein, it can be absorbed hundreds of times its own weight in moisture. It is applied in a pea-sized amount from a jar straight onto the armpit. Other ingredients include cocoa butter, Shea butter, vitamin E, magnesium hydroxide, baking soda, and a proprietary blend of 11 essential oils.
# Mastacembelus tanganicae

Mastacembelus tanganicae is a species of fish in the family Mastacembelidae. It is endemic to Lake Tanganyika where it occurs in shallow areas with a rocky substrate.
# Plaine-d'Argenson

Plaine-d'Argenson (French pronunciation:) is a commune in the department of Deux-Sèvres, western France. The municipality was established on 1 January 2018 by merger of the former communes of Prissé-la-Charrière (the seat), Belleville, Boisserolles and Saint-Étienne-la-Cigogne.
# Placosaris apoalis

Placosaris apoalis is a moth in the family Crambidae. It was described by Eugene G. Munroe and Akira Mutuura in 1970. It is found on Mindanao in the Philippines.
# Placosaris

Placosaris is a genus of snout moths in the subfamily Pyraustinae of the family Crambidae. It is placed in the tribe Pyraustini.
The genus currently comprises 25 species, which are exclusively distributed in the Indomalayan realm and New Guinea. A taxonomic revision from 1970 covers the species distributed in Temperate East Asia.

## Species

Placosaris leucula species group:
* Placosaris callistalis (Hampson, 1896)
* Placosaris cricophora (West, 1931)
* Placosaris egerialis (Snellen, 1899)
* Placosaris galogalis Munroe & Mutuura, 1970
* Placosaris ingestalis (Snellen, 1899)
* Placosaris leucula Meyrick, 1897
* Placosaris triticalis Kenrick 1907
* Placosaris turiusalis (Walker, 1859)
Placosaris intensalis species group:
* Placosaris arjunoalis Munroe & Mutuura, 1970
* Placosaris auranticilialis (Caradja, 1925)
* Placosaris coorumba (Hampson, 1891)
* Placosaris dohertyi Munroe & Mutuura, 1970
* Placosaris intensalis (Swinhoe, 1894)
* Placosaris lindgreni Munroe & Mutuura, 1970
* Placosaris ochreipunctalis (Warren, 1896)
* Placosaris rubellalis (Caradja, 1925)
* Placosaris steelei Munroe & Mutuura, 1970
* Placosaris subfuscalis (Caradja in Caradja & Meyrick, 1933)
* Placosaris swanni Munroe & Mutuura, 1970
* Placosaris taiwanalis (Shibuya, 1928)
* Placosaris ustulalis (Hampson, 1896)
Unplaced in any species group:
* Placosaris apoalis Munroe & Mutuura, 1970
* Placosaris bornealis Munroe & Mutuura, 1970
* Placosaris perakalis Munroe & Mutuura, 1970
* Placosaris udealis Munroe & Mutuura, 1970
# Pitra Neto

António Domingos Pitra Costa Neto (born 12 February 1958) is an Angolan politician, professor and lawyer. Neto joined the Popular Movement for the Liberation of Angola (MPLA) in 1974. He has been a member of the MPLA's central committee since 1998. Since joining the party Neto has been involved in the legal system, both in the civilian and military systems as well as assistant lecturer in law. In 1991 Neto was involved in the negotiations that preceded the Bicesse Accords, which temporarily ended the Angolan civil war. Since 1992, Neto has been the Minister of Public Administration, Employment and Social Security.
Neto was the third candidate on the MPLA's national list in the September 2008 parliamentary election. He won a seat in this election, in which MPLA won an overwhelming majority in the National Assembly.
# Matania (surname)

Matania is a surname. Notable people with the surname include:
* Clelia Matania (1918–1981), Italian actress
* Edoardo Matania (1847–1929), Italian painter and illustrator
* Eviatar Matania (born 1966), Israeli professor and government official
* Fortunino Matania (1881–1963), Italian artist
* Shaul Matania (1937–2017), Israeli footballer
* Ugo Matania (1888–1963), Italian artist and illustrator
# Platypux

Platypux was a French Linux distribution of the Slackware family, developed by Pierre-Aimé and Jacques-Olivier.

## History

Despite Platypux being a Slackware derivative, it was built using the source code provided by the Linux From Scratch project (LFS) that enables the developers to learn the internal workings of a Linux-based system, in order to build a custom Linux distro, so it can naturally fit on its intended audience and purposes.
Platypux V8.0 is only supported by x86 (32bits) platforms, both desktop and laptops, it is available for install from a live-DVD. Its kernel supports PAE in order to enable full access to RAM memory over the 4GiB limit.

## Origin of the name

Platypux has been developed using the source code from the Linux From Scratch project, but also counts on source code for BLFS (Beyond Linux From Scratch) and ALFS (Automated Linux From Scratch) Linux distros. The Linux kernel alongside the several preinstalled packages comprehend the Linux distribution.
Platypux is a pun of platypus and tux, the Linux mascot. A platypus is an exotic animal which despite being a mammal shares oviparity with amphibians an others, making it an exotic Linux distro with parts from "penguins", a GNU and other third party components.

## Preinstalled software packages

Some of the preinstalled packages for Platypux V8.0 are:
* Xfce Window Manager.
* GIMP image editor (with XSane support)
* Inkscape Scalable Vector Graphics editor.
* SRWare Iron web browser.
* Pidgin instant messaging.
* The LibreOffice suite.

## Versions

The release history of Platypux is as follows:
* Version 1.0 released on December 29, 2008. First version, Slackware based.
* V2.0 released on February 20, 2009. Support added for USB flash drive and other removable drives, support for the Wacom tablet and other upgrades.
* V3.0 released on April 19, 2009. Featured Conky and Wifi-radar
* V4.0 released on September 2, 2009. From this version on, WiFi setup is saved on each PC. Java MPlayer 1.0 is introduced.
* V5.0 released on June 13, 2010. System compiled from the LFS and BLFS source code.
* V6.0 released on January 1, 2011. LibreOffice added. Libraries and utilities were updated. Linux 2.6.36 kernel sources are available in the live DVD. Save configuration was improved. WICD is used for network configuration. A package manager was added for building and downloading lzm.
* V7.0 released on May 29, 2011. NFS was corrected, the gFTP client and wireless device firmware was added. Linux kernel 2.6.37.6 added with AUFS and LZMA support. Thunderbird was introduced.
* V8.0 released on November 9, 2011. Several applets added (sound, keyboard, batteries, and others), NVIDIA graphics card support with privative drivers (can be activated thanks to nvidia-xconfig). Added XZM compression for AUFS. XFCE window manager replaces Openbox.
* V9.0 is to be announced, it is under development.
# Massira

Massira may refer to :
* Massira, Marrakech, a sector of Marrakesh made up of several small neighborhoods and housing estates. It is located in the Menara district located to the west of the city.
* Al Massira Airport, Agadir, Morocco international airport
* Jeunesse Massira, a sport club
* Stade El Massira, a multi-use stadium in Safi, Morocco
# Placemat

A placemat or table mat is a covering or pad designating an individual place setting, unlike the larger tablecloth that covers the entire surface. Placemats are made from many different materials, depending on their purpose: to protect, decorate, entertain or advertise. Materials and production methods range from mass-produced and commercial, to local and traditional.

## Uses

Their primary function is to protect the dinner table from water marks, food stains or heat damage. They also serve as decoration, especially placemats made from lace or silk. In restaurants, they can be used to advertise menu items, specials, local businesses or games for children. If the mat is cotton, it can absorb water and other liquids, such as spilt drinks.
# Lachaud

Lachaud is a French surname. Notable people with the surname include:
* Bastien Lachaud (born 1980), French politician representing la France Insoumise
* Joseph Lachaud de Loqueyssie (1848–1896), deputy of Tarn-et-Garonne
* Yvan Lachaud (born 1954), member of the National Assembly of France
# Deebo Bhattacharya discography

Deebo Bhattacharya (1930–1994) was a Pakistani-Bangladeshi music director. The following is a list of films he scored:

## filmography

| Year | Film | Notes |
| 1957 | Maska Polish | |
| 1960 | Yeh Duniya | |
| 1961 | Lakhon Fasanay | |
| 1961 | Hum Ek Hain | |
| 1962 | Banjaran | |
| 1963 | Qatl Ke Baad | |
| 1963 | Shararat | |
| 1963 | Shikwa | |
| 1964 | Beti | |
| 1965 | Aarzoo | |
| 1966 | Badnaam | |
| 1966 | Taqdeer | |
| 1967 | Bahadur | |
| 1967 | Mere Bachche Meri Aankhen | |
| 1968 | Ek Hi Raasta | |
| 1968 | Samundar | |
| 1969 | Pyaar Ki Jeet | |
| 1970 | Baazi | jointly composed with Sohail Rana |
| 1970 | Chand Suraj | |
| 1970 | Honeymoon | |
| 1970 | Jhuk Gaya Aasmaan | |
| 1971 | Baazigar | |
| 1974 | Dilwale | |
| 1974 | Tiger Gang | |
| 1975 | Charitraheen | Winner : Bangladesh National Film Award for Best Music Direction |
| 1978 | Bodhu Biday | composed alongside Alauddin Ali |
| 1982 | Ashar Alo | |
| 1982 | My Love | |
| Unreleased | Jaltay Arman Bujhtay Deep | |
# Jelisaveta Načić

Jelisaveta Načić (31 December 1878 – 6 June 1955) was a notable Serbian architect. She is remembered as a pioneer who inspired women to enter professions which had earlier been reserved for men. Not only the first female graduate in architecture in Belgrade, she was also the first female architect in Serbia.

## Biography

Born in Belgrade, Načić matriculated from school with excellent results in 1896. She went on to study architecture at the University of Belgrade's School of Architecture at a time when it was felt that women should not enter the profession. At the age of 22, she was the first woman to graduate from the Faculty of Engineering. She sought employment at the Ministry of Construction, but was unable to become an official, as there was a requirement for military service to have been completed. She did however succeed in gaining a position as an architect with the Municipality of Belgrade, where she became the city's first chief architect. In 1903, she designed the Little Staircase in Belgrade's Kalemegdan Park. Her most notable work is the well-proportioned school building she completed in 1906, now known as the Kralj Petar I (King Peter I) Elementary School. She also designed churches, including the Moravian-styled Alexander Nevsky Church (1929) in Belgrade and a smaller church in Kosovo. The hospital she designed was destroyed during the Second World War, but many of her residential buildings from apartments to distinctive private homes, some with Art Nouveau or Neo-Renaissance elements, still stand today. The first collective housing building for workers on Balkan was designed by Jelisaveta Načić.
During World War I, she was interned in the Nezsider (today Neusiedl am See, Austria) concentration camp in Hungary, bringing her artistic career to an end. It had lasted no more than 16 years. After the war, Načić moved to Dubrovnik with her Albanian husband, Luka Lukai, whom she had met in the camp. She was awarded a state pension for her life accomplishments. She died in Dubrovnik in 1955.
# Konuklu, Besni

Konuklu is a village in the Besni District, Adıyaman Province, Turkey. Its population is 578 (2021).
The hamlets of Cakalı, Göndürme, İznik, Körosmanlı and Sarıçiçek are attached to the village.
# Chuuk

Chuuk or Truk may refer to:
* Chuuk State, one of the four states of the Federated States of Micronesia
* Chuuk Lagoon, or Chuuk Atoll, a sheltered body of water and island group in the central Pacific
* Chuuk International Airport, an airport located on Weno, in Chuuk State, Micronesia
* Chuukese language, a language of the Austronesian language family
* Chuukese people, an ethnic group in Oceania
* Battle of Truk, a massive United States Navy air and surface attack on Truk Lagoon on 17–18 February 1944