OpenLLM-France/wikimedia huggingface dataset:
# Mutation Frequency Decline

Mutation Frequency Decline (mfd) is the gene which encodes the protein Mfd (also known as Transcription Repair Coupling Factor, TRCF). Mfd functions in transcription-coupled repair to remove a stalled RNA polymerase that has encountered DNA damage and is unable to continue translocating.
The protein is named after the fact that it reduces the chances of suppressor mutations in UV-irradiated cells (or rather, knockout cells show higher rates of such mutations). It does not reduce the chance of every kind of mutation. In fact, it seems to increase the chances of mutation in general, helping to evolve new traits such as antimicrobial resistance.

## Molecular function

Mfd utilizes ATP to translocate along DNA, most likely forcing RNA polymerase forward and ultimately dissociating it from the DNA template. Mfd also contains binding domains which recruit UvrA and trigger the associated nucleotide excision repair pathway and was initially discovered when its mutation led to a decrease in mutation rates after irradiation by UV light. Structural studies of E. coli Mfd by X-ray crystallography have revealed that this molecule is autoinhibited for UvrA-binding in its apo form due to a "clamp" interaction between the N-terminal UvrB-homology module and the C-terminal domain.
In 2002, it was shown that Mfd may also re-initiate transcription at backtracked RNAP by forcing the polymerase forward and out of its backtracked state.

## Cellular consequence
### Evolution of antibiotic resistance

In 2015, Merrikh Lab at University of Washington discovered that Mfd quickens the bacterial mutation process. This work researches ways to slow the rate of bacterial mutations and to block their evolution, in order to fight against antibiotic resistance.
In 2022, a small molecule inhibitor of Mfd was identified by the Merrikh lab. As expected, it slowed down the evolution of antibiotic resistance.

### Tolerance of nitrogen monoxide

Animal immune systems try to kill bacteria in a number of ways, one being the release of nitrogen monoxide (NO). NO damages bacterial DNA, but some species can survive this attack by expressing Mfd.
# The Kitty Wells Show

The Kitty Wells Show is a live album recorded at a concert by Kitty Wells, her son Bobby Wright, her husband Johnny Wright, singer Bill Phillips, and musicians Tommy Jackson, Paul Yandell and Odell Martin. The album was released in 1966 on the Decca label (DL 4831) in the United States and on the Brunswick label (LAT 8674) in the United Kingdom.
Wells sings on four of the album's tracks, including a live version of her signature song, "It Wasn't God Who Made Honky Tonk Angels". One of the songs from the album, "It's All Over (But the Crying)", reached No. 14 on the Billboard country chart in July 1966.
Thom Owens of Allmusic called it "entertaining" and "fun".

## Track listing

Side A
* Tommy Jackson, Introduction: "Sugar in the Gourd" [0:45]
* Kitty Wells, "You Left Your Mark On Me" [2:23]
* Kitty Wells, "It's All Over (But the Crying)" [2:25]
* Paul Yandell, "These Boots Are Made for Walking" [2:20]
* Bill Phillips, "Lonely Street" [2:45]
* Bobby Wright, "Act Naturally" [2:30]
* Johnny Wright, "Don't Give Up the Ship" [2:00]
* Tommy Jackson, Ending: "Sugar in the Gourd" [0:45]
Side B
* Tommy Jackson, Introduction: "Porked Deer" [0:35]
* Kitty Wells, "Love's Enough for Me" [2:25]
* Kitty Wells, "It Wasn't God Who Made Honky Tonk Angels" [2:25]
* Paul Yandell And Odell Martin, "Jamaican Reel" [2:00]
* Bill Phillips, "The Lies Just Can't Be True" [2:13]
* Bobby Wright, "Singing Country Music Loud and Strong" [1:42]
* Johnny Wright, "Can the Circle Be Unbroken" [2:05]
* Tommy Jackson, Ending: "Porked Deer" [0:45]
# KGRE

KGRE may refer to:
* KGRE (AM), a radio station (1450 AM) licensed to serve Greeley, Colorado, United States
* KGRE-FM, a radio station (102.1 FM) licensed to serve Estes Park, Colorado
# Office of Critical Infrastructure Protection and Emergency Preparedness

The Office of Critical Infrastructure Protection and Emergency Preparedness (OCIPEP) is a Canadian government bureau that was created during Anne McLellan's tenure at the Department of Public Safety and Emergency Preparedness (PSEP).
In line with the April 2004 Martin government policy document entitled Securing an Open Society: Canada's National Security Policy, the OCIPEP was removed from the ambit of the Department of National Defence into the PSP.

## History

Canada's civil defence measures evolved over time. As with many other matters in Canada, responsibility is shared between the federal and provincial government. The first post-WWII civil defence co-ordinator was appointed in October 1948 "to supervise the work of federal, provincial and municipal authorities in planning for public air-raid shelters, emergency food and medical supplies, and the evacuation of likely target areas".
In 1959, the Government of Canada, under John Diefenbaker handed authority for civilian defense to the Emergency Measures Organisation (EMO). Large fallout shelters, known as "Diefenbunkers" were built at rural locations outside major cities across Canada at the height of the Cold War during the infancy of the ICBM threat.
The EMO then became Emergency Planning Canada in 1974, then Emergency Preparedness Canada in 1986. In February 2001, the Government replaced Emergency Preparedness with the Office of Critical Infrastructure Protection and Emergency Preparedness (OCIPEP), responsible for civilian emergency planning in both peace and war.
# Christoph Arnold

Christoph Arnold (17 December 1650 – 15 April 1695) was a German farmer and amateur astronomer.

## Life

Born in Sommerfeld near Leipzig, Arnold was a farmer by profession. Interested in astronomy, he spotted the great comet of 1683, eight days before Hevelius did. He also observed the great comet of 1686. In 1686, Kirch went to Leipzig. There, he observed the great comet of 1686, together with Gottfried Kirch. There, Kirch met his second wife, Maria Margarethe Winckelmann (1670–1720), who had actually learned astronomy from Arnold.
Arnold observed the transit of Mercury in front of the sun on 13 October 1690. For this work, he received some money and a tax exemption from the town of Leipzig. He was the author of Göttliche Gnadenzeichen, in einem Sonnenwunder vor Augen gestellt (Leipzig, 1692) which contains an account of the transit of Mercury in 1690. He died at Leipzig.

## Honors

Lunar crater Arnold and asteroid 121016 Christopharnold were named in his honor. The asteroid's official naming citation was published by the Minor Planet Center on 29 October 2012 (M.P.C. 81070).
# Tetrapyrgos

Tetrapyrgos is a genus of fungi in the mushroom family Marasmiaceae. The genus has a widespread distribution and contains 16 species.

## Species

* T. aequatorialis
* T. alba
* T. atrocyanea
* T. austrochilensis
* T. dendrophora
* T. diplocystis
* T. goniospora
* T. nigripes
* T. olivaceonigra
* T. peullensis
* T. reducta
* T. simulans
* T. stipitata
* T. subcinerea
* T. subdendrophora
* T. tropicalis
# Munagekar

The Munagekar Family hails from the village of Munage near Devgad. In the 1820, most of them moved to various parts of Maharashtra due to plague. The Munagekars were very intelligent and often called by many industrialist to solve complex mathematical and engineering problems.
Munagekar is the surname of a number of families in India and abroad. Munagekars generally speak Marathi as their mother tongue. The origin of this surname can be linked to the village Munge in the Sindhudurg district of southern Maharashtra. The Munagekars belong to a number of castes including Saraswat Brahmins, Karhade Brahmins, Sutars and also some scheduled castes.

## Origin

The origin of this surname is primarily linked to the village of Munge. The "kar" at the end is a common feature of Maharashtrian surnames. However, there exist quite a number of Munagekars who have no link whatsoever with this village. A number of people who use this surname and are Karhade Brahmins trace their origins to the surname Padhye. Another group trace their origin to the surname Manjrekar.

## History

The people who adopted this surname originally lived in Goa. It was due to the Portuguese attack on Goa that they had to flee to Munge. It is believed that earlier they were Padyes. Some of them are Brahmins but most are scheduled castes and scheduled tribes. Their deity is Mahalasa of Mardol, Goa. However some of these Munagekars have their roots in the village of Ghodge, which is in Maharashtra.
# Jiro Ando

Jiro Ando (安藤 慈朗, Andō Jirō) is a Japanese manga artist notable as being the artist of the manga Shion no Ō.
He also created the manga version of Bushido Sixteen.
# Boy Scouts van Suriname

Boy Scouts van Suriname is the national Scouting organization of Suriname. Scouting in Suriname officially started in 1924 and became a member of the World Organization of the Scout Movement (WOSM) in 1968. The coeducational association has 2,601 members (as of 2004).

## History

On September 12, 1910, the "Korps Surinamese Boy Scouts" was established in Thalia. In 1915 the name was "Surinaamsche Padvinders Organisatie". There was no more activity, after Scouting was blamed for the drowning of 16-year-old Boy Scout, Herman Sas Römer, on March 13, 1916 in the Dominékreek near Poelepantje. Scouting in Suriname officially restarted on July 29, 1924, when the Surinamese district of the Vereeniging de Nederlandsche Padvinders (NPV) was officially founded in the Thalia theatre in Paramaribo. On this occasion, 107 Boy Scouts, many Cub Scouts and some girls made their Scout Promise.
In 1938, the Dutch Scout movement was split after a decision of the Roman Catholic episcopate into the interreligious NPV and the Katholieke Verkenners (KV). Scouting in Suriname had to follow this despite all protests, so the Katholieke Verkenners Suriname (KVS) were founded out of the Catholic members of the groups. The logo of the KVS was the same as the KV, a Fleur-de-lis for Boy Scouts, on a cross potent for Catholic Scouts.
During World War II, the Surinamese Scouts had to stand alone, since Scouting was banned in the German-occupied Netherlands. So, after the war, the Suriname district of NPV decided to found its own, nearly independent association, the Surinaamse Padvinders Vereniging (SPV), which was incorporated in 1964. SPV and KVS worked close together and received recognition by WOSM in 1968, seven years before the independence of Suriname. After four years of cooperation both association merged and formed the Boy Scouts van Suriname on April 23, 1972. The first Chief Scout was Johan Ferrier.
In 1974, the new association hosted the 5th Caribbean Jamboree.

## Program

The association is divided in three age-groups:
* Cub Scouts (ages 7 to 12)
* Scouts (ages 12 to 18)
* Rover Scouts (ages 18 to 24)
The Scout Motto is Weest Paraat, Be Prepared in Dutch, and Weest Pareet in Sranan Tongo.
# Tapani

Tapani may refer to:
* Tapani (name), a Finnish male given name
* Tapani (surname), a Finnish surname
* Tapani, Iran, a village in Kermanshah Province, Iran
* Tapani Incident, an armed uprising against Japanese rule in Taiwan
# Nicolas Zafra

Nicolas Zafra (21 December 1892 - 7 January 1979) was a Filipino historian and educator. He was professor emeritus of history at the University of the Philippines. He died on January 7, 1979. He was the president of the Philippine Historical Association in 1962 and was a recipient of the Cultural Heritage Award of the Philippines in 1969.

## Early life and education

Zafra was born on December 21, 1892, in San Fernando, La Union. His parents were Pia Alviar and Eugenio Zafra. He had two sisters, Maria Zafra Susara and Mercedes Zafra and two brothers, Balbino Zafra and Dr. Urbano Alviar Zafra (genealogy of Zafra family.) The Zafra family was quite active in local politics. He obtained his elementary and part of his secondary education in San Fernando. He studied at Manila High School, where he graduated in 1912.
In the University of the Philippines, he acquired three degrees: Bachelor of Arts in 1916, Bachelor of Education in 1918, and Master of Arts, major in history, in 1920. From 1939 to 1940, he pursued graduate studies in history at the University of Minnesota.

## Career

Zafra began his career in 1917, as assistant instructor in the department of history of the U.P.
He became full professor and head of the history department in 1948, serving as such for a full ten years. Still head of the history department, he was appointed member of the Social Science Research Center (SSRC) upon its organization under its chairman Dean Tomas Fonacier of the U.P. College of Liberal Arts.
From 1952 to 1953, he was a Fulbright research grantee. In 1955, he was invited by the American Academy of Asian Studies in San Francisco as its visiting professor.
He was a member of the Philippine Historical Association, Philippine National Historical Society, National Research Council of the Philippines, and the International Association Historians of Asia. He was the president of the Philippine Historical Association in 1962.
He also undertook investigations and research into Philippine historical landmarks and personalities, both prominent and obscure, as well as prepared and wrote historical biographies, particularly of the members of the Malolos Congress, and the text of various historical markers. In 1963, the University of the Philippines conferred on him the rare title of professor emeritus of history.
He also received the Cultural Heritage Award, which the Philippine government presented to him in 1969.
Zafra was married to fellow academician Professor Luz Alzona. He had two daughters: Sister Lourdes, a nun, and Felicidad.

## Main works

* Historicity of Rizal’s Retraction (Bookmark, 1961). In this book, he defended the retraction, and called it "a plain, unadorned fact of history, having all the marks and indications of historical certainty and reality."
* A Short History of the Philippines (1966)
* Philippine History Through Selected Sources (1967)
* Oriental History (co-authored with Ganzon).
# Highway 10 (Israel)

Highway 10 is a road in the South District of Israel. It is one of the longest routes in Israel, extending for nearly the entire border of Israel with Egypt from the Gaza Strip in the north to Sayarim junction in the south. Under a military security advisory, its entire 113-mile length is almost permanently off-limits to civilian traffic.

## Features

The route begins in the north with the communities of Hevel Eshkol in the west, nearest to the Sinai Desert. The northern terminus is the intersection with Route 232 near Kerem Shalom. From there, it continues south adjacent to the border with Egypt. It passes by Nitzana and the Nitzana border crossing.
Highway 10 intersects with Route 211, which leads east toward Yeruham and Sde Boker. Farther south, Highway 10 intersects with Route 171, which leads east toward Mizpe Ramon.
The route continues south until Sayarim junction, where it meets Highway 12 in the mountains near Eilat. Highway 12 continues south to Eilat.

## Partial rerouting

A rerouting of part of the highway was approved by Israeli planning authorities in 2012. A 30-kilometer-long section of the highway will be relocated east, further away from Israel's border with Egypt than the original route. Originally, the plan had called for two lanes of traffic in either direction. After appeals from the Society for the Protection of Nature in Israel and other conservationists, who argued that the new highway would profoundly impact the local dune-based environment, the plan was modified to one traffic lane in either direction.

## Junctions (South to North)

| District | Location | km | mi | Name | Destinations |
| Southern | Sayarim Valley | 0.00 | 0.00 | צומת סיירים (Sayarim Junction) | Highway 12 |
| Southern | Mount Harif | 98.49 | 61.20 | צומת הר חריף (Mount Harif Junction) | Route 171 |
| Southern | Nitzana Border Crossing | 152.79 | 94.94 | צומת מבוא חורב (Horev Entrance Junction) | Route 211 |
| Southern | Near Kerem Shalom | 192.51 | 119.62 | צומת ליד כרם שלום (Junction near Kerem Shalom) | Route 232 |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi |||||||
# Tetrapyrgia

Tetrapyrgia is a genus of moths of the family Noctuidae.
# Muricopsis deformis

Muricopsis deformis is a species of sea snail, a marine gastropod mollusk in the family Muricidae, the murex snails or rock snails.

## Distribution

The type locality for its junior synonym, Risomurex mosquitensis is Puerto Vargas, Cahuita National Park, Mosquito Gulf, Costa Rica.
# Peterton, Kansas

Peterton is an unincorporated community in Osage County, Kansas, United States.

## History

A post office was opened in Peterton in 1876, and remained in operation until it was discontinued in 1904.
# Omiodes poliochroa

Omiodes poliochroa is a moth in the family Crambidae. It was described by George Hampson in 1917. It is found in Peru.
# Gorky 5

Professional ratings :
| Review scores ||
| Source | Rating |
| AllMusic | |
| The Guardian | |
Gorky 5 is the fifth album by Welsh band Gorky's Zygotic Mynci, released on 27 August 1998. It was their last album for Mercury Records and features the singles "Let's Get Together (In Our Minds)" and "Sweet Johnny".

## Track listing

All songs written by E. Childs, unless otherwise stated.
* "The Tidal Wave" – 3:04
* "Dyle Fi" – 3:00
* "Let's Get Together (In Our Minds)" – 3:15
* "Tsunami" – 3:42 (Lawrence)
* "Not Yet" – 3:41 (Lawrence)
* "Only the Sea Makes Sense" – 2:45
* "Softly" – 5:59 (Lawrence)
* "Frozen Smile" – 1:24
* "Sweet Johnny" – 4:42
* "Theme from Gorky 5 (Russian Song)" – 4:06
* "Hush the Warmth" – 3:28
* "Catrin" – 3:06

## Personnel

* Euros Childs - vocals, piano, organ, electric piano, synths, timpani (1), bass (5), guitar (6)
* John Lawrence - guitar, vocals, piano (4,5,7), mandolin (3,4), organ (2,4,5), bass (12), pedal steel (4,6), electric piano (6)
* Richard James - bass, guitar (5,6,11,12), organ (9)
* Megan Childs - violin, vocals, viola (2)
* Euros Rowlands - drums, percussion, sub-bass (7)
* Gorwel Owen - vox bass (1), synth (11), harmonium (12)
* Lindsay Higgs - balalaika (10)
* Sonia Slany - violin and string arrangements (3,4)
* Anna Hemery - violin (3,4)
* Jackie Norry - violin (3,4)
* Julie Singleton - violin (3,4)
* Jocelyn Pook - viola (3,4)
* Jackie Woods - viola (3,4)
* Dinah Beamish - cello (3,4)
* Sophie Harris - cello (3,4)
# Tapanhuacanga

Tapanhuacanga is a genus of flowering plants in the family Rubiaceae. It includes 11 species endemic to Brazil.

## Species

11 species are accepted.
* Tapanhuacanga asparagoides (Mart. & Zucc.) P.L.R.Moraes
* Tapanhuacanga bahiensis (J.A.M.Carmo, Sobrado & R.M.Salas) P.L.R.Moraes
* Tapanhuacanga campinorum (K.Krause) P.L.R.Moraes
* Tapanhuacanga cururuensis (J.H.Kirkbr.) P.L.R.Moraes
* Tapanhuacanga goiasensis (J.H.Kirkbr.) P.L.R.Moraes
* Tapanhuacanga intermedia (E.L.Cabral & Bacigalupo) P.L.R.Moraes
* Tapanhuacanga laricoides (Mart. & Zucc.) P.L.R.Moraes
* Tapanhuacanga phyllocephala (K.Schum.) P.L.R.Moraes
* Tapanhuacanga psyllocarpoides (Sucre) P.L.R.Moraes
* Tapanhuacanga scatignae (J.A.M.Carmo, Sobrado & R.M.Salas) P.L.R.Moraes
* Tapanhuacanga schwackei (K.Schum.) P.L.R.Moraes

### Formerly placed here

* Diadorimia densifolia (Zappi & Calió) J.A.M.Carmo, Florentín & R.M.Salas (as Tapanhuacanga densifolia (Zappi & Calió) P.L.R.Moraes)
# Purbeck Valley Folk Festival

The Purbeck Valley Folk Festival is a folk music festival held on the Isle of Purbeck in Dorset, England.
The inaugural event was organized in August 2009 near Kimmeridge Bay as the Purbeck Folk Festival. In 2014, the festival was held during 22–24 August at Wilkswood Farm, Langton Matravers, and had an attendance of 2,400 visitors. In 2015, the festival adopted its current name and moved to Purbeck Valley Farm in Harman's Cross.
It takes place over three days across five stages, and in addition to the music includes workshops, Purbeck Rising, Purbeck Poetry Slam, a children’s area with crafts, storytelling, puppet shows, theatre/games, circus skills and clowns, youth music workshops, a craft area (including crochet, clay, origami, candle, jewellery and tutu making) and a healing area.

## Artists who have appeared at Purbeck Valley Folk Festival

Headlining acts at the festivals since 2015 include:
2015: Richard Thompson, Hot Rize, Justin Currie, Stornaway, Chris Difford, Kathryn Tickell and the Side
2016: Villagers, The Proclaimers, Eliza Carthy and the Wayward Band, Kathryn Roberts and Seth Lakeman
2017: Turin Brakes, Gabby Young, Badly Drawn Boy, Kathryn Williams, This is the Kit, Michele Stodart, Lady Maisery and 3 Daft Monkeys
2018: King Creosote, Richard Thompson Electric Set, Beth Orton, Elephant Sessions
2019: Thea Gilmore, Afro Celt Sound System, Cara Dillon Band, 3 Daft Monkeys, Flook
2021: Thea Gilmore, Afro Celt Sound System, Cara Dillon Band, 3 Daft Monkeys, Flook
2022: Jackie Oates and John Spiers, Glenn Ross and The Caverick Sisters
2023: The Magic Numbers, Newton Faulkner, Sarah Jarosz, Seth Lakeman, Kathryn Williams, Lady Nade

## Purbeck Rising

Purbeck Rising showcases up and coming talent. It is an opportunity for bands, duos or singer songwriters to perform in front of a panel of judges from other local folk festivals including Wimborne, Wessex and Bridport Folk Festivals, after taking part in a selection process.
Previous performers include:
2023: Aayushi, Amica, Arquebus Trio, The Ashen Keys, Laura Loh, Rachel Hill
2022: Rob Clamp, Megan Linford, Den Miller Music, Igloo Hearts, Anna Renae, 14 Wolves
# High Stakes & Dangerous Men

Professional ratings :
| Review scores ||
| Source | Rating |
| AllMusic | |
| Collector's Guide to Heavy Metal | 4/10 |
High Stakes & Dangerous Men is the thirteenth album by British hard rock band UFO, released in February 1992. It is the only UFO studio album to feature guitarist Laurence Archer and drummer Clive Edwards, both former members of Wild Horses.

## Track listing

All songs written by Phil Mogg, Pete Way, and Laurence Archer, except where indicated.

## Personnel
### UFO

* Phil Mogg - vocals
* Laurence Archer - guitar, backing vocals
* Pete Way - bass guitar
* Clive Edwards - drums

### Additional musicians

* Don Airey – keyboards
* Terry Reid, Stevie Lange - backing vocals

### Production

* Kit Woolven - producer, engineer, arrangements with UFO
# New Taipei City Yingge Ceramics Museum

The New Taipei City Yingge Ceramics Museum (traditional Chinese: 新北市立鶯歌陶瓷博物館; simplified Chinese: 新北市立莺歌陶瓷博物馆; pinyin: Xīnběi Shìlì Yīnggē Táocí Bówùguǎn) is a museum presenting ceramics located in Yingge District, New Taipei, Taiwan.

## History

The museum opened on 26 November 2000. In March 2016, the museum signed an agreement with Google to include its collections in the art project of Google Cultural Institute.

## Exhibitions

The museum houses exhibits as well as a ceramics studio. The permanent exhibits present five major themes:
* Traditional Pottery Techniques Hall
* Once they Were: Development of Taiwan Ceramics
* Pottery Town: History of Yingge
* Shuttle Through Time: Prehistoric/Aboriginal/Contemporary Ceramics
* Future Prediction: Industrial and High-tech Ceramics
There is also an experimental pottery area for children to play with clay, and a pottery workshop for artists and experts to share experiences and thoughts.

## Transportation

The museum is accessible within walking distance South West from Yingge Station of Taiwan Railways.
# Chinnaraviryala

Chinnaraviryala is a village in Ranga Reddy district in Telangana, India. It falls under Abdullapurmet mandal.